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https://www.readbyqxmd.com/read/28422526/acupuncture-on-renal-function-in-patients-with-chronic-kidney-disease-a-single-blinded-randomized-preliminary-controlled-study
#1
Jung-Sheng Yu, Chung-Han Ho, Hsien-Yi Wang, Yung-Hsiang Chen, Ching-Liang Hsieh
OBJECTIVE: To evaluate the feasibility effect of acupuncture on renal function in patients with chronic kidney disease (CKD). METHODS: In total, 59 patients with CKD were randomized into acupuncture (AG; n = 30) and sham acupuncture (CG; n = 29) treatment groups. In the AG, acupuncture was applied to bilateral Hegu (LI4), Zusanli (ST36), and Taixi (KI3) to obtain qi, and electroacupuncture (2 Hz) was applied to two acupoint pairs (right Zusanli and Taixi and left Zusanli and Taixi) once per week for 12 weeks...
April 19, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28400811/effect-of-electroacupuncture-on-the-mrna-and-protein-expression-of-rho-a-and-rho-associated-kinase-ii-in-spinal-cord-injury-rats
#2
You-Jiang Min, Li-Li-Qiang Ding, Li-Hong Cheng, Wei-Ping Xiao, Xing-Wei He, Hui Zhang, Zhi-Yun Min, Jia Pei
Electroacupuncture is beneficial for the recovery of spinal cord injury, but the underlying mechanism is unclear. The Rho/Rho-associated kinase (ROCK) signaling pathway regulates the actin cytoskeleton by controlling the adhesive and migratory behaviors of cells that could inhibit neurite regrowth after neural injury and consequently hinder the recovery from spinal cord injury. Therefore, we hypothesized electroacupuncture could affect the Rho/ROCK signaling pathway to promote the recovery of spinal cord injury...
February 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28393479/inhibitory-effects-and-mechanisms-of-electroacupuncture-via-chronically-implanted-electrodes-on-stress-induced-gastric-hypersensitivity-in-rats-with-neonatal-treatment-of-iodoacetamide
#3
Jingzhu Zhou, Shiying Li, Yinping Wang, Robert D Foreman, Jieyun Yin, Shengsheng Zhang, Jiande D Z Chen
BACKGROUND: Stress is considered an independent factor causing and aggravating gastrointestinal symptoms, including visceral pain. The aim of this study was to investigate effects and mechanisms of electroacupuncture (EA) on stress-induced gastric hypersensitivity in rats treated with neonatal iodoacetamide mimicking human functional dyspepsia (FD). METHODS: Neonatal rats were treated with gavage of 0.2 mL of 0.1% iodoacetamide in 2% sucrose daily for six days starting on tenth day after birth...
April 10, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28358020/nmr-based-metabolomics-reveals-alterations-of-electro-acupuncture-stimulations-on-chronic-atrophic-gastritis-rats
#4
Jingjing Xu, Xujuan Zheng, Kian-Kai Cheng, Xiaorong Chang, Guiping Shen, Mi Liu, Yadong Wang, Jiacheng Shen, Yuan Zhang, Qida He, Jiyang Dong, Zongbao Yang
Chronic atrophic gastritis (CAG) is a common gastrointestinal disease which has been considered as precancerous lesions of gastric carcinoma. Previously, electro-acupuncture stimulation has been shown to be effective in ameliorating symptoms of CAG. However the underlying mechanism of this beneficial treatment is yet to be established. In the present study, an integrated histopathological examination along with molecular biological assay, as well as (1)H NMR analysis of multiple biological samples (urine, serum, stomach, cortex and medulla) were employed to systematically assess the pathology of CAG and therapeutic effect of electro-acupuncture stimulation at Sibai (ST 2), Liangmen (ST 21), and Zusanli (ST 36) acupoints located in the stomach meridian using a rat model of CAG...
March 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28352122/long-term-electrical-stimulation-at-ear-and-electro-acupuncture-at-st36-st37-attenuated-cox-2-in-the-ca1-of-hippocampus-in-kainic-acid-induced-epileptic-seizure-rats
#5
En-Tzu Liao, Nou-Ying Tang, Yi-Wen Lin, Ching Liang Hsieh
Seizures produce brain inflammation, which in turn enhances neuronal excitability. Therefore, anti-inflammation has become a therapeutic strategy for antiepileptic treatment. Cycloxygenase-2 (COX-2) plays a critical role in postseizure brain inflammation and neuronal hyperexcitability. Our previous studies have shown that both electrical stimulation (ES) at the ear and electro-acupuncture (EA) at the Zusanli and Shangjuxu acupoints (ST36-ST37) for 6 weeks can reduce mossy fiber sprouting, spike population, and high-frequency hippocampal oscillations in kainic acid (KA)-induced epileptic seizure rats...
March 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28316166/-analgesic-effect-and-related-mechanism-of-peripheral-acupoints-electroacupuncture-on-superficial-partial-thickness-burn-rats
#6
X Sun, Z R Wei, Z Xiao
Objective: To observe the analgesic effect and related mechanism of peripheral acupoints electroacupuncture on superficial partial-thickness burn rats. Methods: Eighty SD rats were divided into sham injury group (SI), pure burn group (PB), electroacupuncture group (E), and sham electroacupuncture group (SE) according to the random number table, with 20 rats in each group. Right posterior leg of rats in group SI were sham injured, while superficial partial-thickness scald (hereinafter referred to as burn) model was reproduced on the right posterior leg of rats in the latter three groups...
March 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28289242/acupuncture-attenuated-vascular-dementia-induced-hippocampal-long-term-potentiation-impairments-via-activation-of-d1-d5-receptors
#7
Yang Ye, Hui Li, Jing-Wen Yang, Xue-Rui Wang, Guang-Xia Shi, Chao-Qun Yan, Si-Ming Ma, Wen Zhu, Qian-Qian Li, Tian-Ran Li, Ling-Yong Xiao, Cun-Zhi Liu
BACKGROUND AND PURPOSE: Emerging evidence suggests that acupuncture could improve cognitive impairment in vascular dementia by enhancing synaptic plasticity in the hippocampus. The purpose of this study is to investigate whether dopamine, a key mediator of synaptic plasticity, is involved in this cognitive improvement. METHODS: Vascular dementia model was established by bilateral common carotid arteries occlusion in male Wistar rats. Three days after the operation, animals received acupuncture treatment for 2 weeks, once daily...
April 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28254097/a-trial-study-of-moxibustion-with-a-warming-needle-on-edema
#8
RANDOMIZED CONTROLLED TRIAL
Wen-Ping Zhang, Yuki Onose, Takahiko Fujikawa
Edema is an accumulation of an excessive amount of watery fluid in cells or intercellular tissues. In order to examine the effects of acupuncture and moxibustion on edema, seven subjects were randomly divided into three groups, that was a Control group, an Acupuncture group (Acp), and an acupuncture and moxibustion group (Acp-Mox). After sitting for 60 minutes keeping their bodies still, the Acp and Acp-Mox subjects were administered acupuncture or acupuncture/moxibustion on the points of Zusanli (ST-36) and Sanyinjiao (SP-6), separately as against the Control group who only lied on the bed after modelization...
January 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28243312/acupuncture-improved-neurological-recovery-after-traumatic-brain-injury-by-activating-bdnf-trkb-pathway
#9
Xiaohong Li, Chong Chen, Xiping Yang, Jingjing Wang, Ming-Liang Zhao, Hongtao Sun, Sai Zhang, Yue Tu
How to promote neural repair following traumatic brain injury (TBI) has long been an intractable problem. Although acupuncture has been demonstrated to facilitate the neurological recovery, the underlying mechanism is elusive. Brain-derived neurotrophic factor (BDNF) exerts substantial protective effects for neurological disorders. In this study, we found that the level of BDNF and tropomyosin receptor kinase B (TrkB) was elevated spontaneously after TBI and reached up to the peak at 12 h. Nevertheless, this enhancement is quickly declined to the normal at 48 h...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28166603/electroacupuncture-attenuates-hyperalgesia-in-rats-withdrawn-from-chronic-alcohol-drinking-via-habenular-mu-opioid-receptors
#10
Jing Li, Caihong Fu, Hongwei Liu, Rao Fu, Wanhong Zuo, Seungwoo Kang, Pei Chen, Danielle Gregor, Rose Paulose, Alex Bekker, Jiang-Hong Ye
BACKGROUND: Hyperalgesia or increased sensitivity to pain is often found in alcoholics during alcohol withdrawal and may contribute to relapse drinking. Alternative therapies such as acupuncture and electroacupuncture (EA), through mechanisms involving opioid receptors, may reduce pain and substance dependence and withdrawal syndromes. The lateral habenula (LHb), an epithalamic structure rich in mu opioid receptors (MORs), is a critical target for both drugs of abuse and pain. We previously observed hyperalgesia in rats withdrawn from chronic ethanol (EtOH) drinking and found that EA at the acupoint Zusanli (ST36) reduced EtOH intake...
March 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28105066/electroacupuncture-for-the-prevention-of-postoperative-gastrointestinal-dysfunction-in-participants-undergoing-vascular-laparotomy-under-general-anesthesia-a-randomized-controlled-trial
#11
Meng-Yue Liu, Cheng-Wei Wang, Zhou-Peng Wu, Ning Li
BACKGROUND: Postoperative gastrointestinal dysfunction (PGD) is a common complication following laparotomy under general anesthesia (GA). Abdominal distension occurs in 8-28% of surgeries within 24 h postoperatively. The present study aimed to analyze the efficacy of electroacupuncture (EA) for the prevention of PGD by applying preoperative EA stimulation of PC6 (Neiguan), ST36 (Zusanli), and ST37 (Shangjuxv) bilaterally twice within 24 h prior to surgery, compared with no acupuncture treatment...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/28069044/effect-of-transcutaneous-electrical-acupoint-stimulation-combined-with-palonosetron-on-chemotherapy-induced-nausea-and-vomiting-a-single-blind-randomized-controlled-trial
#12
Jing Xie, Lei-Hua Chen, Zhou-Yu Ning, Chen-Yue Zhang, Hao Chen, Zhen Chen, Zhi-Qiang Meng, Xiao-Yan Zhu
BACKGROUND: Chemotherapy-induced nausea and vomiting adversely affects the quality of life of patients who receive chemotherapy via intravenous infusion or transcatheter arterial chemoembolization (TACE). This study aimed to investigate the clinical effects of transcutaneous electrical acupoint stimulation (TEAS) on nausea and vomiting after TACE. METHODS: A total of 142 patients who received TACE with cisplatin for primary or metastatic liver cancer were assigned to the active-acupuncture (n = 72) or placebo-acupuncture (n = 70) groups using a covariate-adaptive randomization at a ratio of 1:1...
January 10, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28068994/spatiotemporal-changes-of-optical-signals-in-the-somatosensory-cortex-of-neuropathic-rats-after-electroacupuncture-stimulation
#13
Myeounghoon Cha, Younbyoung Chae, Sun Joon Bai, Bae Hwan Lee
BACKGROUND: Peripheral nerve injury causes physiological changes in primary afferent neurons. Neuropathic pain associated with peripheral nerve injuries may reflect changes in the excitability of the nervous system, including the spinothalamic tract. Current alternative medical research indicates that acupuncture stimulation has analgesic effects in various pain symptoms. However, activation changes in the somatosensory cortex of the brain by acupuncture stimulation remain poorly understood...
January 10, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28049463/coarse-needle-surface-potentiates-analgesic-effect-elicited-by-acupuncture-with-twirling-manipulation-in-rats-with-nociceptive-pain
#14
Sunoh Kwon, Yangseok Lee, Hi-Joon Park, Dae-Hyun Hahm
BACKGROUND: Biomechanical phenomenon called "needle grasp" through the winding of connective tissue has been proposed as an action mechanism of acupuncture manipulation. The aim of the present study is to verify whether the needle grasp force affects the pain-relieving activity of acupuncture in the tail-flick latency (TFL) and the rat paw formalin tests. METHODS: In order to make different roughness on the acupuncture needle surface, the needles with 0.2 mm-diameter were scratched using silicon carbide sandpapers with the grit numbers of 600 (mild coarse) and 200 (extra coarse)...
January 3, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27999821/effects-of-electroacupuncture-on-the-daily-rhythmicity-of-intestinal-movement-and-circadian-rhythmicity-of-colonic-per2-expression-in-rats-with-spinal-cord-injury
#15
Jie Cheng, Xueqiang Wang, Jiabao Guo, Yujie Yang, Wenyi Zhang, Bin Xie, Zhaojin Zhu, Yuemei Lu, Yi Zhu
Background. Spinal cord injury (SCI) leads to bowel dysfunction. Electroacupuncture (EA) may improve bowel function. Objective. To assess EA on daily rhythmicity of intestinal movement and circadian rhythmicity of colonic Per2 expression in rats with SCI. Methods. Rats were randomized to the sham, SCI, and SCI+EA groups. EA was performed at bilateral Zusanli point (ST36) during daytime (11:00-11:30) for 14 days following SCI. Intestinal transit and daily rhythmicity of intestinal movement were assessed. Circadian rhythmicity of colonic Per2 expression was assessed by real-time RT-PCR...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27978835/activation-of-hippocampal-mek1-contributes-to-the-cumulative-antinociceptive-effect-of-electroacupuncture-in-neuropathic-pain-rats
#16
Yong-Hui Gao, Cheng-Wen Li, Jun-Ying Wang, Yu Kan, Lian-Hong Tan, Xiang-Hong Jing, Jun-Ling Liu
BACKGROUND: Electroacupuncture (EA) intervention can relieve a variety of pain; however, optimal EA protocols have not been clearly determined. In addition, although central mitogen-activated protein kinase kinase (MEK) signaling has been shown to be involved in the antinociceptive effect of acupuncture stimulation, its characteristics at different time-points of EA intervention have not been fully elucidated. Therefore, the present study investigated the relationship between the effects of different numbers of EA intervention sessions and the activation of MEK1 in the hippocampus and hypothalamus in a rat model of neuropathic pain...
December 15, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27966183/electro-acupuncture-at-acupoint-st36-ameliorates-inflammation-and-regulates-th1-th2-balance-in-delayed-type-hypersensitivity
#17
Zhigang Wang, Tao Chen, Man Long, Longyun Chen, Lei Wang, Nina Yin, Zebin Chen
Increasing evidence indicates anti-allergic and anti-inflammatory effects of electro-acupuncture (EA) therapy. However, its underlying mechanism on delayed-type hypersensitivity (DTH), a classic allergic inflammatory disease, still remains unclear. In this study, we aimed to explore the immunomodulatory mechanism of EA intervention in a mouse model of ovalbumin (OVA)-induced DTH. Mice were randomly divided into four groups: Control, OVA-DTH, DTH + EA, DTH + Sham. "Zusanli" acupoint (ST36) was used for DTH + EA, whereas a non-acupoint (localized 5 mm below the "Zusanli" acupoint) was selected for DTH + Sham...
April 2017: Inflammation
https://www.readbyqxmd.com/read/27821107/acupuncture-with-different-acupoint-combinations-for-chemotherapy-induced-nausea-and-vomiting-study-protocol-for-a-randomized-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Lili Gao, Bo Chen, Qiwen Zhang, Tianyi Zhao, Bo Li, Tao Sha, Jinxin Zou, Yongming Guo, Xingfang Pan, Yi Guo
BACKGROUND: Acupuncture is beneficial for controlling chemotherapy-induced nausea and vomiting (CINV). However, the effect of different acupoint combinations on controlling CINV remains unknown. This study aims to compare the effects of distal-proximal point association and local distribution point association on controlling CINV. METHODS/DESIGN: The study is a single-center, randomized controlled trial. A total of 240 participants will be randomly divided into four groups...
November 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27800006/the-effect-of-repeated-electroacupuncture-analgesia-on-neurotrophic-and-cytokine-factors-in-neuropathic-pain-rats
#19
Junying Wang, Yonghui Gao, Shuping Chen, Chenlin Duanmu, Jianliang Zhang, Xiumei Feng, Yaxia Yan, Junling Liu, Gerhard Litscher
Chronic pain is a common disability influencing quality of life. Results of previous studies showed that acupuncture has a cumulative analgesic effect, but the relationship with spinal cytokines neurotrophic factors released by astrocytes remains unknown. The present study was designed to observe the effect of electroacupuncture (EA) treatment on spinal cytokines neurotrophic factors in chronic neuropathic pain rats. The chronic neuropathic pain was established by chronic constrictive injury (CCI). EA treatment was applied at Zusanli (ST36) and Yanglingquan (GB34) (both bilateral) once a day, for 30 min...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27753225/photoacoustic-microscopy-of-electronic-acupuncture-ea-effect-in-small-animals
#20
Jinge Yang, Dan Wu, Yong Tang, Huabei Jiang
Acupuncture has been an effective treatment for various pain in China for several thousand years. However, the mechanisms underlying this mysterious ancient healing are still largely unknown. Here we applied photoacoustic microscopy (PAM) to investigate brain hemodynamic changes in response to electronic acupuncture (EA) at ST36 (Zusanli). Due to the high optical absorption of blood at 532 nm, PAM could sensitively probe changes in hemoglobin concentration (HbT, i.e., cerebral blood volume [CBV]) of cortical regions in high resolution...
October 18, 2016: Journal of Biophotonics
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