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Kuo Zhang, Xin-Meng Guo, Ya-Wen Yan, Yang-Yang Liu, Zhi-Fang Xu, Xue Zhao, Jiang Wang, Yi Guo, Kai Li, Sha-Sha Ding
The mechanisms of acupuncture are still unclear. In order to reveal the regulatory effect of manual acupuncture (MA) on the neuroendocrine-immune (NEI) network and identify the key signaling molecules during MA modulating NEI network, we used a rat complete Freund's adjuvant (CFA) model to observe the analgesic and anti-inflammatory effect of MA, and, what is more, we used statistical and complex network methods to analyze the data about the expression of 55 common signaling molecules of NEI network in ST36 (Zusanli) acupoint, and serum and hind foot pad tissue...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Haitao Yu, Xinyu Wu, Lihui Cai, Bin Deng, Jiang Wang
Acupuncture, as an external stimulation, can produce clinical effects via the central nervous system. In order to investigate the modulatory efficacy of acupuncture on brain activity, multichannel EEG signals evoked by acupuncture at "Zusanli" acupoint were recorded from healthy humans in three states: pre-acupuncture, acupuncture, and post-acupuncture. Power spectral density is first used to analyze the EEG power change during acupuncture process. It is found that EEG power significantly increased in the delta and alpha bands under acupuncture and high power level remained in alpha band after acupuncture...
May 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Taishan Tong, Chunqin Pei, Jun Chen, Qing Lv, Fuquan Zhang, Zaohuo Cheng
BACKGROUND Chemotherapy can cause adverse effects such as chemotherapy-related cognitive impairment (CRCI). In this prospective study, the efficacy of traditional Chinese medicine acupuncture therapy in relieving CRCI and its impact on serum brain-derived neurotrophic factor (BDNF) are evaluated. MATERIAL AND METHODS Eighty patients were randomly divided into a treatment group and a control group with 40 patients in each group. The treatment group was treated at the following acupuncture points: Baihui (DU20), Sishencong (EX-HN1), Shenting (DU24), Zusanli (ST36), Taixi (K13), Dazhong (K14), and Juegu (GB39)...
May 8, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Jonathan M Borkum
The success of naturalistic or therapeutic neuroregeneration likely depends on an internal milieu that facilitates the survival, proliferation, migration, and differentiation of stem cells and their assimilation into neural networks. Migraine attacks are an integrated sequence of physiological processes that may protect the brain from oxidative stress by releasing growth factors, suppressing apoptosis, stimulating neurogenesis, encouraging mitochondrial biogenesis, reducing the production of oxidants, and upregulating antioxidant defenses...
April 2018: Neural Regeneration Research
Rui Gao, Shan Gao, Jinteng Feng, Hongying Cui, Yanchao Cui, Junke Fu, Guangjian Zhang
Electroacupuncture (EA) is a therapeutic modality in which the electrical stimulation is integrated with concepts of acupuncture to treat diseases. This study was designed to evaluate the connection between the electro-acupuncture induced increase in Na99m TcO4 uptake in the stomach wall, and the ionic molecule levels in the extracellular fluid in the acupoints. Wistar rats were treated by 2 or 100 Hz EA at Zusanli (ST 36) and Xiajuxu (ST 39) bilaterally for 60 minutes. The accumulation of Na99m TcO4 in the gastric wall and the free ions, including Ca2+ , K+ , Na+ , and Cl- , in the acupoints were measured every 60 minutes...
April 30, 2018: Scientific Reports
Na Yin, Hongwei Yang, Wei Yao, Ying Xia, Guanghong Ding
Nerve and mast cells are densely distributed around acupoints in connective tissue. To explore the internal relations between them in acupuncture effect, we examined dorsal root potential (DRP) response to acupuncture at Zusanli (ST36) under sodium cromoglicate (DSCG, a mast cell stabilizer) intervention in anesthetized Sprague-Dawley (SD) rats. We used single unit nerve recording techniques to collect nerve signals from DRP afferent nerves for a 45-minute period that includes 4 stages, that is, base, drug absorption, acupuncture, and recovery stages...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Jian-Biao Meng, Yan-Na Jiao, Xiu-Juan Xu, Zhi-Zhen Lai, Geng Zhang, Chun-Lian Ji, Ma-Hong Hu
BACKGROUND: A pathological increase in intraabdominal pressure (IAP) and inflammatory responses have negative effects on splanchnic, respiratory, cardiovascular, renal, and neurological function in septic patients with intestinal dysfunction. Electro-acupuncture (EA) has been evidenced to have a bidirectional neuron-endocrine-immune system regulating effect in patients with intestinal dysfunction. The purpose of current study was to evaluate the effects of EA at "Zusanli" (ST36) and "Shangjuxu" (ST37) on inflammatory responses and IAP in septic patients with intestinal dysfunction manifested syndrome of obstruction of the bowels Qi...
April 2018: Medicine (Baltimore)
Lili Zhang, Pengfei Wei, Shaozong Chen
OBJECTIVE: To analyze the present situation and existing problems of acupuncture for primary hypertension (PH) based on clinical research literature in recent 20 years. METHODS: The clinical research literature regarding acupuncture for PH were searched from China National Knowledge Infrastructure (CNKI), VIP data network (VIP) and Wanfang database from 1997 through 2016; a total of 218 papers met the inclusive criteria. Microsoft Excel and Apriori algorithm of SPSS Clementine software were applied to analyze the data...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Xia Chen, Wei Huang, Yiting Jin, Feng Hu, Xiaoling Cheng, Zhehao Hong, Zhongyu Zhou
OBJECTIVE: To analyze the core acupoints and compatibility of electroacupuncture (EA) for simple obesity based on complex network technique, and to explore the usage of EA waveform. METHODS: The clinical research literature regarding EA for simple obesity published from January of 1980 to June of 2016 were searched in PubMed, CNKI, WanFang , VIP, CBM and TCM online database to establish a prescription database of EA for simple obesity. The Matlab2014a software was used to perform the center analysis and cluster analysis, and the analysis of core points and compatibility were conducted...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Rongjuan Cao, Xiaohu Qiu, Xiaokun Xie
OBJECTIVE: To observe the clinical effect difference between special penetration needling and conventional penetration needling for the refractory peripheral facial paralysis. METHODS: A total of 97 patients with intractable facial paralysis were randomized into an observation group (49 cases and 2 dropping) and a control group (48 cases and 4 dropping). In the observation group, special penetration needling at an angle about 45° between the penetration needle and paralysis muscle bundle was used, Yangbai (GB 14) through Touwei (ST 8), Yangbai (GB 14) through Shangxing (GV 23), Sizhukong (TE 23) through Yuyao (EX-HN 4), Qianzhen (Extra) through Yingxiang (LI 20), mutual penetration between Yingxiang (LI 20) and Jiache (ST 6)...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Zhihua Mi, Ju Gao, Xiaoping Chen, Yali Ge, Kaixin Lu
OBJECTIVE: To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) on the quality of recovery during the early period after laparoscopic cholecystectomy and the dosage of anesthetic and analgesic. METHODS: One hundred patients who received laparoscopic cholecystectomy with gradeⅠand Ⅱ of American Society of Anesthesiologists (ASA) criteria were randomly assigned into an observation group and a control group according to random number table, 50 cases in each group...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Guoqing Ma, Ting Ye, Zhongren Sun
OBJECTIVE: To compare the clinical efficacy differences between warming acupuncture and conventional acupuncture for diabetic peripheral neuropathy (DPN) with syndrome of yang deficiency and cold coagulation, obstruction of collaterals and blood stasis. METHODS: A total of 64 patients were randomly divided into a warming acupuncture group and a conventional acupuncture group, 32 cases in each one. Based on basic treatment of blood glucose regulation, warming acupuncture was applied at Pishu (BL 20), Shenshu (BL 23), Guanyuanshu (BL 26), Zusanli (ST 36), Chongyang (ST 42), Quchi (LI 11) and Hegu (LI 4) in the warming acupuncture group, while acupuncture was applied at the identical acupoints in the conventional acupuncture group...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Zhuang Zhang, Yafeng Wang, Junjun Sun, Nijuan Hu, Guiwen Wu, Shangqing Hu, Pei Wang, Minyi Zhao, Liangxiao Ma, Jiang Zhu
OBJECTIVE: The research regarding the central mechanism of acupuncture deqi (arrival of qi ) based on functional magnetic resonance imaging (fMRI) in recent 10 years was analyzed to summarize existing research achievements and experience. METHODS: The literature regarding fMRI-based deqi research published from January of 2007 through December of 2016 in CNKI and PubMed databases was collected. The research content and methods, including research design, inclusion criteria, acupoint selection and deqi evaluation, were analyzed...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Juan Xu, Yu Zuo
OBJECTIVE: To observe the efficacy differences between acupuncture combined with medication and medication alone for infertility patients with polycystic ovary syndrome (PCOS). METHODS: According to random number table, a total of 60 infertility patients with PCOS were randomly assigned into an observation group and a control group, 30 cases in each one. The patients in the control group were treated with diane-35 from the 3rd day into menstruation, and one menstrual cycle was taken as a session of treatment...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Yong Wen, Lei Shi, Jun Li, Weiliang Du, Ye Chen, Xiaolin Lan
OBJECTIVE: To observe the efficacy of acupuncture combined with acupoint catgut embedding sequential therapy and medication for mild and moderate ulcerative colitis. METHODS: One hundred and twenty patients were randomized into an acupuncture and acupoint catgut embedding sequential therapy group (a combination group) and a mesalazine group, 60 cases in each one. Fifty-seven cases in the combination group and 55 cases in the mesalazine group were included into analysis...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Lei Zhou, Hongfang Cai
OBJECTIVE: To observe the effects of acupoint catgut embedding assisting western medication and simple western medication on blood pressure and vascular endothelial function in patients with essential hypertension (EH), and to explore its mechanism. METHODS: A total of 125 cases were randomly assigned into an observation group (62 cases, 2 dropping) and a control group (63 cases, 3 dropping). Oral administration of lotensin (10 mg, once a day) was applied in the control group...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Yi Zhang, Yuzheng Du
OBJECTIVE: Based on the western medication, to evaluate the advantages in the morning blood pressure treated with acupuncture at Fengchi (GB 20) and Neck-Jiaji (EX-B 2) combined with acupuncture technique for activating blood circulation, eliminating wind and regulating the liver and spleen in the patients with essential hypertension. METHODS: A total of 90 patients of essential hypertension of the mild and moderate degrees were randomized into a medication group (30 cases, 3 dropping), No...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Jaung-Geng Lin, Shinn-Zong Lin, Lih-Hwa Lin, Chun-Chang Wu, Wan-Ting Tsai, Horng-Jyh Harn, Li-Hui Su, Wen-Yu Ho, Che-Jui Hsieh, Tsung-Jung Ho
Moxibustion () is a traditional Chinese medicine therapy performed using Artemisia argyii. Zusanli (, ST36) is an acupoint in the stomach meridian, long associated in ancient Chinese medical practices with the extension of life span when moxibustion is applied to it. The aim of this study was to investigate changes in insulin-like growth factor 1 (IGF-1) levels after application of moxibustion to ST36. Four healthy men and women participated in this 28-day trial and were randomly divided into 2 groups. Group A received moxibustion treatment from days 1 to 14, while group B received moxibustion treatment from days 15 to 28...
January 1, 2018: Cell Transplantation
Bok-Nam Seo, Ji-Eun Park, Young-Eun Kim, Kyung-Won Kang, In-Chan Seol, Sun-Mi Choi
Background: Hypertension is a major cause of cardiovascular disease and associated mortality, and postmenopausal women are at a high risk of hypertension. We aim to investigate the hypotensive effect and safety of acupuncture, focusing on postmenopausal women with prehypertension and stage 1 hypertension. In addition, we aim to investigate whether the effect of acupuncture treatment differed, depending on Sasang Constitution and cold-heat pattern. Methods: This study is designed as an intervention cohort study...
March 2018: Integrative Medicine Research
Chun-Lei Zhou, Lan Zhao, Hui-Yan Shi, Jian-Wei Liu, Jiang-Wei Shi, Bo-Hong Kan, Zhen Li, Jian-Chun Yu, Jing-Xian Han
Sanjiao acupuncture and HuangDiSan can promote the proliferation, migration and differentiation of exogenous neural stem cells in senescence-accelerated mouse prone 8 (SAMP8) mice and can improve learning and memory impairment and behavioral function in dementia-model mice. Thus, we sought to determine whether Sanjiao acupuncture and HuangDiSan can elevate the effect of neural stem cell transplantation in Alzheimer's disease model mice. Sanjiao acupuncture was used to stimulate Danzhong (CV17), Zhongwan (CV12), Qihai (CV6), bilateral Xuehai (SP10) and bilateral Zusanli (ST36) 15 days before and after implantation of neural stem cells (5 × 105 ) into the hippocampal dentate gyrus of SAMP8 mice...
March 2018: Neural Regeneration Research
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