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https://www.readbyqxmd.com/read/28231689/are-children-with-asthma-in-south-korea-also-associated-with-vitamin-d-deficiency
#1
Yu-Ri Kim, Sung-Chul Seo, Young Yoo, Ji Tae Choung
Recently, epidemiologic studies have shown that the lack of vitamin D levels may be associated with high asthma prevalence, but its effect is still controversial, depending on season, area, and food consumption. We aimed to examine the association of serum vitamin D levels with the prevalence of pediatric asthma in Korea. A total of 80 children (50 asthmatic children and 30 healthy controls) aged 6-14 years were participated in this study. Serum 25-hydroxy vitamin D (vitamin D) levels were measured and compared between the two groups...
February 14, 2017: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28231548/spatiotemporal-exposome-dynamics-of-soil-lead-and-children-s-blood-lead-pre-and-ten-years-post-hurricane-katrina-lead-and-other-metals-on-public-and-private-properties-in-the-city-of-new-orleans-louisiana-u-s-a
#2
Howard W Mielke, Christopher R Gonzales, Eric T Powell, Paul W Mielke
BACKGROUND: Anthropogenic re-distribution of lead (Pb) principally through its use in gasoline additives and lead-based paints have transformed the urban exposome. This unique study tracks urban-scale soil Pb (SPb) and blood Pb (BPb) responses of children living in public and private communities in New Orleans before and ten years after Hurricane Katrina (29 August 2005). OBJECTIVES: To compare and evaluate associations of pre- and ten years post-Katrina SPb and children's BPb on public and private residential census tracts in the core and outer areas of New Orleans, and to examine correlations between SPb and nine other soil metals...
February 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28230800/mutilating-procedures-management-practices-and-housing-conditions-that-may-affect-the-welfare-of-farm-animals-implications-for-welfare-research
#3
Rebecca E Nordquist, Franz Josef van der Staay, Frank J C M van Eerdenburg, Francisca C Velkers, Lisa Fijn, Saskia S Arndt
A number of mutilating procedures, such as dehorning in cattle and goats and beak trimming in laying hens, are common in farm animal husbandry systems in an attempt to prevent or solve problems, such as injuries from horns or feather pecking. These procedures and other practices, such as early maternal separation, overcrowding, and barren housing conditions, raise concerns about animal welfare. Efforts to ensure or improve animal welfare involve adapting the animal to its environment, i.e., by selective breeding (e...
February 21, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28230581/a-handoffs-software-led-to-fewer-errors-of-omission-and-better-provider-satisfaction-a-randomized-control-trial
#4
Markos G Kashiouris, Christos Stefanou, Deepankar Sharma, Cecilia Yshii-Tamashiro, Ryan Vega, Sarah Hartingan, Charles Albrecht, Robert H Brown
BACKGROUND: Computer-assisted communication is shown to prevent critical omissions ("errors") in the handoff process. OBJECTIVE: The aim of the study was to study this effect and related provider satisfaction, using a standardized software. METHODS: Fourteen internal medicine house officers staffed 6 days and 1 cross-covering teams were randomized to either the intervention group or control, employing usual handoff, so that handoff information was exchanged only between same-group subjects (daily, for 28 days)...
February 22, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28229973/female-conspecifics-restore-rhythmic-singing-behaviour-in-arrhythmic-male-zebra-finches
#5
Neelu Anand Jha, Vinod Kumar
The present study investigated whether pairing with a conspecific female would restore rhythmicity in the singing behaviour of arrhythmic male songbirds. We recorded the singing and, as the circadian response indicator, monitored the activity-rest pattern in male zebra finches (Taeniopygia guttata) housed without or with a conspecific female under 12 h light: 12 h darkness (12L:12D) or constant bright light (LL bright). Both unpaired and paired birds exhibited a significant daily rhythm in the singing and activity behaviour, but paired birds, under 12L:12D, showed a ~2 h extension in the evening...
March 2017: Journal of Biosciences
https://www.readbyqxmd.com/read/28229462/harmonization-of-nucleic-acid-testing-for-zika-virus-development-of-the-1-st-world-health-organization-international-standard
#6
Sally A Baylis, Kay-Martin O Hanschmann, Barbara S Schnierle, Jan-Hendrik Trösemeier, Johannes Blümel
BACKGROUND: With the ongoing public health emergency due to Zika virus (ZIKV), nucleic acid testing (NAT) is essential for clinical diagnosis and screening of blood donors. However, NAT for ZIKV has not been standardized, and this study was performed to establish a World Health Organization (WHO) International Standard (IS) for ZIKV RNA; WHO ISs have been used to improve detection and quantification of blood-borne viruses. STUDY DESIGN AND METHODS: The candidate IS (cIS), code number 11468/16, was prepared by heat inactivation and lyophilization of a ZIKV strain isolated from a patient in French Polynesia in 2013...
February 23, 2017: Transfusion
https://www.readbyqxmd.com/read/28229260/dehydroepiandrosterone-sulfate-dhea-s-sex-and-age-in-zoo-housed-western-lowland-gorillas-gorilla-gorilla-gorilla
#7
Ashley N Edes
Among humans, dehydroepiandrosterone-sulfate (DHEA-S) declines with age and is hypothesized to be involved in somatic maintenance and healthy aging. Men have significantly higher DHEA-S than women, contradicting longer lifespans in the latter. Declines of DHEA-S with age also are observed in chimpanzees. In both chimpanzees and bonobos, males and females show no differences in DHEA-S production. Based on human and chimpanzee data, gorillas were predicted to show declining DHEA-S with age. Similar to chimpanzees and bonobos, it also was predicted DHEA-S would not be significantly different between males and females...
February 22, 2017: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/28228560/expression-of-il-22-in-the-skin-causes-th2-biased-immunity-epidermal-barrier-dysfunction-and-pruritus-via-stimulating-epithelial-th2-cytokines-and-the-grp-pathway
#8
Hongfei Lou, Jingning Lu, Eun Byul Choi, Min Hee Oh, Mingeum Jeong, Sara Barmettler, Zhou Zhu, Tao Zheng
Increased expression of Th22 cytokine IL-22 is a characteristic finding in atopic dermatitis (AD). However, the specific role of IL-22 in the pathogenesis of AD in vivo has yet to be elucidated. Consistent with observations in human AD, IL-22 was significantly increased in the AD skin of mice after epicutaneous sensitization to house dust mite allergen. Utilizing a skin-specific inducible transgenic system, we show in the present study that expression of IL-22 in the skin of mice caused an AD-like phenotype characterized by chronic pruritic dermatitis associated with Th2-biased local and systemic immune responses, downregulation of epidermal differentiation complex genes, and enhanced dermatitis upon epicutaneous allergen exposure...
February 22, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28228516/trial-and-error-copying-of-demonstrated-actions-reveals-how-fledglings-learn-to-imitate-their-mothers
#9
Noa Truskanov, Arnon Lotem
Understanding how humans and other animals learn to perform an act from seeing it done has been a major challenge in the study of social learning. To determine whether this ability is based on 'true imitation', many studies have applied the two-action experimental paradigm, examining whether subjects learn to perform the specific action demonstrated to them. Here, we show that the insights gained from animals' success in two-action experiments may be limited, and that a better understanding is achieved by monitoring subjects' entire behavioural repertoire...
February 22, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28228475/parallel-evolution-of-mound-building-and-grass-feeding-in-australian-nasute-termites
#10
Daej A Arab, Anna Namyatova, Theodore A Evans, Stephen L Cameron, David K Yeates, Simon Y W Ho, Nathan Lo
Termite mounds built by representatives of the family Termitidae are among the most spectacular constructions in the animal kingdom, reaching 6-8 m in height and housing millions of individuals. Although functional aspects of these structures are well studied, their evolutionary origins remain poorly understood. Australian representatives of the termitid subfamily Nasutitermitinae display a wide variety of nesting habits, making them an ideal group for investigating the evolution of mound building. Because they feed on a variety of substrates, they also provide an opportunity to illuminate the evolution of termite diets...
February 2017: Biology Letters
https://www.readbyqxmd.com/read/28228196/the-hidden-story-of-innovation-charity-hospital-angola-prison-and-the-challenging-of-surgical-dogma
#11
Patrick Greiffenstein, Paul R Hastings
The late 1960s was a period of significant upheaval of social, cultural, and scientific norms. The generally accepted notion of mandatory laparotomy for all penetrating abdominal injuries was among those norms being called into question across the country and many advocated expectant management of selected patients presenting with this type of injury. Leaders of the surgical community published opinions on either side of the argument. The house staff at Charity Hospital during this period was among the busiest in the nation in treating these injuries, many of them inmates of the Louisiana State Penitentiary who used self-inflicted stab wounds to the abdomen as a means of temporary respite from the inhumane conditions in the prison...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28228176/the-state-of-american-health-care-november-2016-to-november-2020-a-look-forward
#12
Theodore Marmor, Michael K Gusmano
The election of Donald Trump, coupled with the retention of Republican majorities in the US House of Representatives and Senate, raises questions about future of the Patient Protection and Affordable Care Act, the structure and funding of the country's public health insurance programs - Medicare, Medicaid and the Child Health Insurance Program - and the direction of health policy in the United States, more generally. Political scientists are not renowned for their capacity to predict the future and many of those who forecast election results have received criticism in recent weeks for failing to predict the Trump victory...
February 23, 2017: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/28228160/assessment-of-lymphatic-filariasis-prior-to-re-starting-mass-drug-administration-campaigns-in-coastal-kenya
#13
Sammy M Njenga, Henry M Kanyi, Faith M Mutungi, Collins Okoyo, Hadley S Matendechero, Rachel L Pullan, Katherine E Halliday, Simon J Brooker, C Njeri Wamae, Joyce K Onsongo, Kimberly Y Won
BACKGROUND: Lymphatic filariasis (LF) is a debilitating disease associated with extensive disfigurement and is one of a diverse group of diseases referred to as neglected tropical diseases (NTDs) which mainly occur among the poorest populations. In line with global recommendations to eliminate LF, Kenya launched its LF elimination programme in 2002 with the aim to implement annual mass drug administration (MDA) in order to interrupt LF transmission. However, the programme faced financial and administrative challenges over the years such that sustained annual MDA was not possible...
February 22, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28226902/investigation-on-the-hermeticity-of-an-implantable-package-with-32-feedthroughs-for-neural-prosthetic-applications
#14
Lorenzo Bisoni, Matthias Mueller, Paul Cvancara, Caterina Carboni, Roberto Puddu, Luigi Raffo, Massimo Barbaro, Thomas Stieglitz, Lorenzo Bisoni, Matthias Mueller, Paul Cvancara, Caterina Carboni, Roberto Puddu, Luigi Raffo, Massimo Barbaro, Thomas Stieglitz, Roberto Puddu, Luigi Raffo, Lorenzo Bisoni, Matthias Mueller, Paul Cvancara, Caterina Carboni, Massimo Barbaro, Thomas Stieglitz
This paper presents an implantable package aimed at hosting a bidirectional neural interface for neural prosthetic applications. The package has been conceived to minimize the invasivity for the patient, for this reason a cylindrical container with an outer diameter of 7 mm and a length of 21 mm has been designed. The package, realized in alumina (Al2O3), presents 32 hermetic feedthroughs located at the top and bottom base of the cylinder. The hermetic housing has been assembled using a low-temperature soldering method based on a previous platinum/gold (Pt/Au) metallization of the ceramic parts...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226830/on-the-development-of-a-low-cost-emg-switch-for-communication-using-minimal-muscle-contractions
#15
Begona Garcia-Conde, Christopher J James, Begona Garcia-Conde, Christopher J James, Begona Garcia-Conde, Christopher J James
In the final stages of muscle-wasting diseases like Amyotrophic Lateral Sclerosis and in extreme cases of disability the control of muscles is almost completely lost. However, in some cases there can be almost imperceptible residual control of some muscles. This paper presents the results of a study using an affordable, lightweight, portable EMG switch that has been designed in-house for communication in severely disabled or locked-in patients. It is possible to affect communication with the outside world by using these small residual muscle movements; in this case, more specifically muscles around the eyebrow...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226567/an-effective-3-fingered-augmenting-exoskeleton-for-the-human-hand
#16
C J Gearhart, B Varone, M H Stella, B F BuSha, C J Gearhart, B Varone, M H Stella, B F BuSha, M H Stella, B F BuSha, B Varone, C J Gearhart
Every year, thousands of Americans suffer from pathological and traumatic events that result in loss of dexterity and strength of the hand. Although many supportive devices have been designed to restore functional hand movement, most are very complex and expensive. The goal of this project was to design and implement a cost-effective, electrically powered exoskeleton for the human hand that could improve grasping strength. A 3-D printed thermoplastic exoskeleton that allowed independent and enhanced movement of the index, middle and ring fingers was constructed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226013/suicide-attempts-by-exposure-to-toxic-agents-registered-in-a-toxicological-information-and-assistance-center-in-fortaleza-cear%C3%A3-brazil-2013
#17
Ana Paula Soares Gondim, Rachel Rabay Nogueira, João Gabriel Barbosa Lima, Rayra Aguiar Campos Lima, Polianna Lemos Moura Moreira Albuquerque, Maria do Socorro Batista Veras, Maria Augusta Drago Ferreira
Objective: to describe cases of suicide attempts by exposure to toxic agents registered by the Toxicological Information and Assistance Center in Fortaleza, Ceará, Brazil. Methods: this is a descriptive study using secondary data of the cases registered in 2013. Results: 410 cases were registered; 56.2% of the individuals were female and 79.7% were between 12 and 39 years old; most of them (86.4%) lived in urban areas and 67.2%, in Fortaleza; in 94...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28225909/tuberculosis-as-a-marker-of-inequities-in-the-context-of-socio-spatial-transformation
#18
Alexandre San Pedro, Gerusa Gibson, Jefferson Pereira Caldas Dos Santos, Luciano Medeiros de Toledo, Paulo Chagastelles Sabroza, Rosely Magalhães de Oliveira
OBJECTIVE: This study aims to analyze the association between the incidence of tuberculosis and different socioeconomic indicators in a territory of intense transformation of the urban space. METHODS: This is an ecological study, whose analysis units were the neighborhoods of the city of Itaboraí, state of Rio de Janeiro, Brazil. The data have been analyzed by generalized linear models. The response variable was incidence of tuberculosis from 2006 to 2011. The independent variables were the socio-demographic indicators...
February 16, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28225820/analysis-of-spatial-mobility-in-subjects-from-a-dengue-endemic-urban-locality-in-morelos-state-mexico
#19
Jorge Abelardo Falcón-Lezama, René Santos-Luna, Susana Román-Pérez, Ruth Aralí Martínez-Vega, Marco Arieli Herrera-Valdez, Ángel Fernando Kuri-Morales, Ben Adams, Pablo Antonio Kuri-Morales, Malaquías López-Cervantes, José Ramos-Castañeda
INTRODUCTION: Mathematical models and field data suggest that human mobility is an important driver for Dengue virus transmission. Nonetheless little is known on this matter due the lack of instruments for precise mobility quantification and study design difficulties. MATERIALS AND METHODS: We carried out a cohort-nested, case-control study with 126 individuals (42 cases, 42 intradomestic controls and 42 population controls) with the goal of describing human mobility patterns of recently Dengue virus-infected subjects, and comparing them with those of non-infected subjects living in an urban endemic locality...
2017: PloS One
https://www.readbyqxmd.com/read/28225594/mass-spectral-feature-list-optimizer-ms-flo-a-tool-to-minimize-false-positive-peak-reports-in-untargeted-lc-ms-data-processing
#20
Brian C Defelice, Sajjan Singh Mehta, Stephanie Samra, Tomas Cajka, Benjamin Wancewicz, Johannes F Fahrmann, Oliver Fiehn
Untargeted metabolomics by liquid chromatography-mass spectrometry generates data rich chromatograms in form of m/z-retention time features. Managing such datasets is a bottleneck. Many popular data processing tools, including XCMS-online and MZmine2, yield numerous false positive peak detections. Flagging and removing such false peaks manually is a time consuming task and prone to human error. We present a web application, MS Feature List Optimizer (MS-FLO), to improve the quality of feature lists after initial processing to expedite the process of data curation...
February 22, 2017: Analytical Chemistry
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