keyword
MENU ▼
Read by QxMD icon Read
search

Blueprinting and assessment

keyword
https://www.readbyqxmd.com/read/29886854/underlying-trend-seasonality-prediction-forecasting-and-the-contribution-of-risk-factors-an-analysis-of-globally-reported-cases-of-middle-east-respiratory-syndrome-coronavirus
#1
Omar B Da'ar, Anwar E Ahmed
This study set out to identify and analyse trends and seasonal variations of monthly global reported cases of the Middle East respiratory syndrome coronavirus (MERS-CoV). It also made a prediction based on the reported and extrapolated into the future by forecasting the trend. Finally, the study assessed contributions of various risk factors in the reported cases. The motivation for this study is that MERS-CoV remains among the list of blueprint priority and potential pandemic diseases globally. Yet, there is a paucity of empirical literature examining trends and seasonality as the available evidence is generally descriptive and anecdotal...
June 11, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29847586/mr-cbct-image-guided-system-for-radiotherapy-of-orthotopic-rat-prostate-tumors
#2
Tsuicheng D Chiu, Tatsuya J Arai, James Campbell Iii, Steve B Jiang, Ralph P Mason, Strahinja Stojadinovic
Multi-modality image-guided radiotherapy is the standard of care in contemporary cancer management; however, it is not common in preclinical settings due to both hardware and software limitations. Soft tissue lesions, such as orthotopic prostate tumors, are difficult to identify using cone beam computed tomography (CBCT) imaging alone. In this study, we characterized a research magnetic resonance (MR) scanner for preclinical studies and created a protocol for combined MR-CBCT image-guided small animal radiotherapy...
2018: PloS One
https://www.readbyqxmd.com/read/29800747/pd-l1-immunohistochemistry-comparability-study-in-real-life-clinical-samples-results-of-blueprint-phase-2-project
#3
Ming Sound Tsao, Keith M Kerr, Mark Kockx, Mary-Beth Beasley, Alain C Borczuk, Johan Botling, Lukas Bubendorf, Lucian Chirieac, Gang Chen, Teh-Ying Chou, Jin-Haeng Chung, Sanja Dacic, Sylvie Lantuejoul, Mari Mino-Kenudson, Andre L Moreira, Andrew G Nicholson, Masayuki Noguchi, Giuseppe Pelosi, Claudia Poleri, Prudence A Russell, Jennifer Sauter, Erik Thunnissen, Ignacio Wistuba, Hui Yu, Murry W Wynes, Melania Pintilie, Yasushi Yatabe, Fred R Hirsch
The Blueprint (BP) PD-L1 immunohistochemistry (IHC) comparability project is a pivotal academic/professional society and industrial collaboration to assess the feasibility of harmonizing the clinical use of five independently developed commercial PD-L1 IHC assays. The goals of BP phase 2 (BP2) were to validate the results obtained in BP1, using real world clinical lung cancer samples (n=81) of various histological and sample types, with all five trial-validated PD-L1 assays (22C3, 28-8, SP142, SP263, and 73-10), by an international panel of pathologists...
May 22, 2018: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29793376/longitudinal-assessments-in-continuing-specialty-certification-and-lifelong-learning
#4
David W Price, David B Swanson, Mira B Irons, Richard E Hawkins
Longitudinal assessment (LA) involves the regular, spaced delivery of a limited number of questions on practice relevant content on a computer or mobile internet platform. Depending on the platform, participants may indicate relevance of the content to their practice and confidence in their answer prior to receiving immediate feedback (including critiques) on each question. Individual dashboards may be included to assist participants in tracking progress and identifying areas of strength and weaknesss across a content blueprint...
May 24, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29772837/conventional-pathology-versus-gene-signatures-for-assessing-luminal-a-and-b-type-breast-cancers-results-of-a-prospective-cohort-study
#5
Julia E C van Steenhoven, Anne Kuijer, Paul J van Diest, Joost M van Gorp, Marieke Straver, Sjoerd G Elias, Jelle Wesseling, Emiel Rutgers, Johanna N H Timmer-Bonte, Peter Nieboer, Tineke J Smilde, Alex Imholz, Charlotte F J M Blanken, Sabine Siesling, Thijs van Dalen
In this study, in estrogen receptor positive (ER+) early stage breast cancer patients who were considered candidates for 70-gene signature (70-GS, "MammaPrint") use, we compared molecular subtyping (MS) based on the previously validated 80-gene signature (80-GS, "BluePrint") versus surrogate pathological subtyping (PS). Between 1 January 2013 and 31 December 2015, 595 clinical intermediate risk ER+ early stage breast cancer patients were enrolled. Hormone receptor (HR) and HER2 receptor status were determined by conventional pathology using immunohistochemistry (IHC) and fluorescent in situ hybridization (FISH)...
May 17, 2018: Genes
https://www.readbyqxmd.com/read/29769728/emerging-trends-in-global-freshwater-availability
#6
M Rodell, J S Famiglietti, D N Wiese, J T Reager, H K Beaudoing, F W Landerer, M-H Lo
Freshwater availability is changing worldwide. Here we quantify 34 trends in terrestrial water storage observed by the Gravity Recovery and Climate Experiment (GRACE) satellites during 2002-2016 and categorize their drivers as natural interannual variability, unsustainable groundwater consumption, climate change or combinations thereof. Several of these trends had been lacking thorough investigation and attribution, including massive changes in northwestern China and the Okavango Delta. Others are consistent with climate model predictions...
May 16, 2018: Nature
https://www.readbyqxmd.com/read/29769290/assessment-of-an-organ-specific-de-novo-transcriptome-of-the-nematode-trap-crop-solanum-sisymbriifolium
#7
Alexander Q Wixom, N Carol Casavant, Joseph C Kuhl, Fangming Xiao, Louise-Marie Dandurand, Allan B Caplan
Solanum sisymbriifolium , also known as "Litchi Tomato" or "Sticky Nightshade," is an undomesticated and poorly researched plant related to potato and tomato. Unlike the latter species, S. sisymbriifolium induces eggs of the cyst nematode, Globodera pallida , to hatch and migrate into its roots, but then arrests further nematode maturation. In order to provide researchers with a partial blueprint of its genetic make-up so that the mechanism of this response might be identified, we used single molecule real time (SMRT) sequencing to compile a high quality de novo transcriptome of 41,189 unigenes drawn from individually sequenced bud, root, stem, and leaf RNA populations...
May 16, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29769096/a-methodology-for-generating-a-tailored-implementation-blueprint-an-exemplar-from-a-youth-residential-setting
#8
Cara C Lewis, Kelli Scott, Brigid R Marriott
BACKGROUND: Tailored implementation approaches are touted as more likely to support the integration of evidence-based practices. However, to our knowledge, few methodologies for tailoring implementations exist. This manuscript will apply a model-driven, mixed methods approach to a needs assessment to identify the determinants of practice, and pilot a modified conjoint analysis method to generate an implementation blueprint using a case example of a cognitive behavioral therapy (CBT) implementation in a youth residential center...
May 16, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29759007/contemporary-trends-emerging-in-epigenomics-and-metabolism
#9
Assam El-Osta
Diabetes is the disease of our time. It is a complex disorder. It is increasingly appreciated that genetic factors cannot fully explain susceptibility to diabetic complications. For almost a decade, the epigenetics field has grown tremendously becoming an alternative but integral component of how we interpret gene regulation. Some consider the field an epiphenomenon with an evidence base awaiting critical testing. The advent of experimental tools combined with the development of research methods have brought with the field technological advancements that allow scientists to assess ideas that have not yet been tested critically...
May 15, 2018: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29736079/nonpharmacological-methods-in-managing-patients-with-dementia-in-a-tertiary-care-hospital
#10
Nisha Mani Pandey, Shailendra Mohan Tripathi, Bhupendra Singh, Sarvada Chandra Tiwari
Management of dementia is very crucial. Nonpharmacological methods (NPM) are well appreciated and encouraged to be used as first-line treatment for managing elderly patients with dementia (PwD). The present case reports aimed to share the strategies of NPM for managing PwD. NPM requires a structured blueprint to record, follow-up, and monitor the outcomes. A structured proforma has been developed in the department. After getting all the basic information from the patient, needed assessments are being done by the concerned team member to identify and rate the level of severity of the problem, and specific NPM strategies are being provided...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29720010/an-explanatory-mixed-methods-study-on-the-validity-and-validation-of-students-assessment-results-in-the-undergraduate-surgery-course
#11
Omayma Hamed, Husain Hamza Jabbad, Omar I Saadah, Mahmoud S Al Ahwal, Fatin M Al-Sayes
BACKGROUND/PURPOSE: There is inadequate evidence of reported validity of the results of assessment instruments used to assess clinical competence. This study aimed at combining multiple lines of quantitative and qualitative evidence to support interpretation and use of assessment results. METHOD: This study is a mixed methods explanatory research set in two stages of data collection and analysis (QUAN : qual). Guided by Messick's conceptual model, quantitative evidences as reliability and correlation coefficients of various validity components were calculated using students' scores, grades and success rates of the whole population of students in 2012/2013 and 2013/2014 (n= 383; 326)...
May 2, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29627246/robustness-and-sensitivity-of-a-blueprint-for-on-farm-estimation-of-dairy-cow-energy-balance
#12
Vivi M Thorup, Mizeck G G Chagunda, Amelie Fischer, Martin R Weisbjerg, Nicolas C Friggens
Excessive negative energy balance (EB) has been associated with decreased reproductive performance and increased risk of lameness and metabolic diseases. On-farm, automated EB estimates for individual cows would enable dairy farmers to detect excessive negative EB early and act to minimize its extent and duration by altering feeding. Previously, we have shown that EB can be estimated from frequent measurements of body weight (BW) and body condition score (BCS) changes, referred to as EBbody . In this study, we investigated the robustness and sensitivity of the EBbody method to assess its genericity and on-farm applicability...
April 4, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29610050/upmc-s-blueprint-for-building-a-high-value-health-care-system
#13
Donna Keyser, Jane Kogan, Marion McGowan, Pamela Peele, Diane Holder, William Shrank
National-level demonstration projects and real-world studies continue to inform health care transformation efforts and catalyze implementation of value-based service delivery and payment models, though evidence generation and diffusion of learnings often occurs at a relatively slow pace. Rapid-cycle learning models, however, can help individual organizations to more quickly adapt health care innovations to meet the challenges and demands of a rapidly changing health care landscape. Integrated delivery and financing systems (IDFSs) offer a unique platform for rapid-cycle learning and innovation...
March 30, 2018: Healthcare
https://www.readbyqxmd.com/read/29606896/deconstructing-programmatic-assessment
#14
Tim J Wilkinson, Michael J Tweed
We describe programmatic assessment and the problems it might solve in relation to assessment and learning, identify some models implemented internationally, and then outline what we believe are programmatic assessment's key components and what these components might achieve. We then outline some issues around implementation, which include blueprinting, data collection, decision making, staff support, and evaluation. Rather than adopting an all-or-nothing approach, we suggest that elements of programmatic assessment can be gradually introduced into traditional assessment systems...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29578847/development-of-quality-indicators-to-assess-oral-anticoagulant-management-in-community-pharmacies-for-patients-with-atrial-fibrillation
#15
Mylène Chartrand, Line Guénette, Denis Brouillette, Stéphane Côté, Roger Huot, Jérôme Landry, Josée Martineau, Sylvie Perreault, Brian White-Guay, David Williamson, Élisabeth Martin, Marie-Mireille Gagnon, Lyne Lalonde
BACKGROUND: Few studies have evaluated the quality of oral anticoagulant management by community pharmacists. There is no complete set of quality indicators available for this purpose. OBJECTIVE: To develop a set of specific quality indicators to assess oral anticoagulant management by community pharmacists for patients with atrial fibrillation (AF). METHODS: Quality indicators were developed in 3 phases. In phase 1, potential quality indicators were generated based on clinical guidelines and a literature review...
April 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29562511/clinical-trials-for-disease-modifying-therapies-in-alzheimer-s-disease-a-primer-lessons-learned-and-a-blueprint-for-the-future
#16
Jeffrey Cummings, Aaron Ritter, Kate Zhong
Alzheimer's disease (AD) has no currently approved disease-modifying therapies (DMTs), and treatments to prevent, delay the onset, or slow the progression are urgently needed. A delay of 5 years if available by 2025 would decrease the total number of patients with AD by 50% in 2050. To meet the definition of DMT, an agent must produce an enduring change in the course of AD; clinical trials of DMTs have the goal of demonstrating this effect. AD drug discovery entails target identification followed by high throughput screening and lead optimization of drug-like compounds...
March 16, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29492360/developing-a-knowledge-test-for-a-neonatal-ethics-teaching-program
#17
Gregory P Moore, Emanuela Ferretti, Thierry Daboval
Objective The innovative Neonatal-Perinatal Medicine (NPM) Ethics Teaching Program at the University of Ottawa provides NPM trainees with vital foundational knowledge required to manage ethically contentious clinical scenarios frequently encountered in practice. In this study, our aim was to develop a knowledge test to assess the impact of the NPM Ethics Teaching Program on trainees' knowledge about ethics. Study design Using an iterative four-step process, we developed a test for assessing pre- and post-training knowledge of NPM ethics...
December 20, 2017: Curēus
https://www.readbyqxmd.com/read/29483115/an-antibiotic-stewardship-program-blueprint-for-optimizing-verigene-bc-gn-within-an-institution-a-tale-of-two-cities
#18
Jason M Pogue, Emily L Heil, Paul Lephart, J Kristie Johnson, Ryan P Mynatt, Hossein Salimnia, Kimberly C Claeys
Rapid diagnostic tests (RDTs) have revolutionized the management of Gram-negative bacteremia by allowing antimicrobial stewardship teams the ability to escalate therapy and improve patient outcomes through timely organism identification and detection of certain resistance determinants. However, given the complex nature of Gram-negative resistance, stewardship teams are left without clear direction for how to respond when resistance determinants are absent, as the safety of de-escalation in this setting is unknown...
May 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29467979/programmatic-assessment-in-emergency-medicine-implementation-of-best-practices
#19
Marcia Perry, Andrew Linn, Brendan W Munzer, Laura Hopson, Ambrosya Amlong, Michael Cole, Sally A Santen
Background : Programmatic assessment is the intentional collection of key data from multiple sources for both assessment of learning and assessment for learning . Objective : We developed a system of programmatic assessment (PA) to identify competency progression (summative) and assessment for learning to assist residents in their formative development. Methods : The programmatic assessment was designed iteratively from 2014 through 2016...
February 2018: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/29459193/personal-domains-assessed-in-multiple-mini-interviews-mmis-for-healthcare-student-selection-a-narrative-synthesis-systematic-review
#20
REVIEW
Alison Callwood, Kamalan Jeevaratnam, Grigorios Kotronoulas, Annegret Schneider, Liane Lewis, Vishna Devi Nadarajah
OBJECTIVES: To examine the personal domains multiple mini interviews (MMIs) are being designed to assess, explore how they were determined and contextualise such domains in current and future healthcare student selection processes DESIGN: A systematic review of empirical research reporting on MMI model design was conducted from database inception to November 2017. DATA SOURCES: Twelve electronic bibliographic databases. REVIEW METHODS: Evidence was extracted from original studies, and integrated in a narrative synthesis guided by the PRISMA statement for reporting systematic reviews...
May 2018: Nurse Education Today
keyword
keyword
42891
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"