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Blueprinting and assessment

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https://www.readbyqxmd.com/read/29440198/developing-a-clinical-approach-to-air-pollution-and-cardiovascular-health
#1
REVIEW
Michael B Hadley, Jill Baumgartner, Rajesh Vedanthan
Nearly 3 billion people are exposed to household air pollution emitted from inefficient cooking and heating stoves, and almost the entire global population is exposed to detectable levels of outdoor air pollution from traffic, industry, and other sources. Over 3 million people die annually of ischemic heart disease or stroke attributed to air pollution, more than from traditional cardiac risk factors such as obesity, diabetes mellitus, or smoking. Clinicians have a role to play in reducing the burden of pollution-attributable cardiovascular disease...
February 13, 2018: Circulation
https://www.readbyqxmd.com/read/29437862/structure-and-functions-of-pediatric-aerodigestive-programs-a-consensus-statement
#2
R Paul Boesch, Karthik Balakrishnan, Sari Acra, Dan T Benscoter, Shelagh A Cofer, Joseph M Collaco, John P Dahl, Cori L Daines, Alessandro DeAlarcon, Emily M DeBoer, Robin R Deterding, Joel A Friedlander, Benjamin D Gold, Rayna M Grothe, Catherine K Hart, Mikhail Kazachkov, Maureen A Lefton-Greif, Claire Kane Miller, Paul E Moore, Scott Pentiuk, Stacey Peterson-Carmichael, Joseph Piccione, Jeremy D Prager, Philip E Putnam, Rachel Rosen, Michael J Rutter, Matthew J Ryan, Margaret L Skinner, Cherie Torres-Silva, Christopher T Wootten, Karen B Zur, Robin T Cotton, Robert E Wood
Aerodigestive programs provide coordinated interdisciplinary care to pediatric patients with complex congenital or acquired conditions affecting breathing, swallowing, and growth. Although there has been a proliferation of programs, as well as national meetings, interest groups and early research activity, there is, as of yet, no consensus definition of an aerodigestive patient, standardized structure, and functions of an aerodigestive program or a blueprint for research prioritization. The Delphi method was used by a multidisciplinary and multi-institutional panel of aerodigestive providers to obtain consensus on 4 broad content areas related to aerodigestive care: (1) definition of an aerodigestive patient, (2) essential construct and functions of an aerodigestive program, (3) identification of aerodigestive research priorities, and (4) evaluation and recognition of aerodigestive programs and future directions...
February 7, 2018: Pediatrics
https://www.readbyqxmd.com/read/29379253/templating-in-uncemented-tha-on-accuracy-and-postoperative-leg-length-discrepancy
#3
Nils J Strøm, Olav Reikerås
Purpose: This study examines the accuracy of digital templating in uncemented total hip arthroplasty (THA), i.e., whether the templated components where actually inserted during surgery. The surgical outcome was evaluated on the basis of limb length equality. Methods: We retrospectively examined digital x-rays of 41 patients scheduled for uncemented THA. These were templated using templating software. The template was compared to the surgical choice of implant registered in the patients' journal...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29368434/the-virtual-anemia-trial-an-assessment-of-model-based-in-silico-clinical-trials-of-anemia-treatment-algorithms-in-patients-with-hemodialysis
#4
Doris H Fuertinger, Alice Topping, Franz Kappel, Stephan Thijssen, Peter Kotanko
In silico approaches have been proposed as a novel strategy to increase the repertoire of clinical trial designs. Realistic simulations of clinical trials can provide valuable information regarding safety and limitations of treatment protocols and have been shown to assist in the cost-effective planning of clinical studies. In this report, we present a blueprint for the stepwise integration of internal, external, and ecological validity considerations in virtual clinical trials (VCTs). We exemplify this approach in the context of a model-based in silico clinical trial aimed at anemia treatment in patients undergoing hemodialysis (HD)...
January 25, 2018: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/29345798/clinical-impact-of-pharmacokinetic-interactions-between-the-hcv-protease-inhibitor-simeprevir-and-frequently-used-concomitant-medications
#5
Fiona Marra, Christoph Höner Zu Siederdissen, Saye Khoo, David Back, Michael Schlag, Sivi Ouwerkerk-Mahadevan, Ceyhun Bicer, Isabelle Lonjon-Domanec, Wolfgang Jessner, Maria Beumont-Mauviel, Ronald Kalmeijer, Markus Cornberg
AIMS: Direct-acting antivirals (DAAs) for the treatment of hepatitis C (HCV) can be associated with drug-drug interactions (DDIs) with concomitant medications. The practical clinical implications of such DDIs are poorly understood. We assessed the clinical impact of possible pharmacokinetic (PK) interactions between simeprevir and frequently prescribed concomitant medications. METHODS: This post-hoc analysis pooled data from 9 studies which evaluated simeprevir (SMV)-based interferon-free HCV treatment...
January 18, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29326486/standardization-and-validation-of-objective-structured-practical-examination-in-pharmacology-our-experience-and-lessons-learned
#6
Preethi J Shenoy, Priyanka Kamath, Vinaykumar Sayeli, Sunil Pai
OBJECTIVES: The present study is an attempt to standardize and establish validity and reliability of objective structured practical examination (OSPE) as a tool of assessment in pharmacology. METHODS: The individual stations were standardized by establishing the blueprint of assessment, checklists for individual OSPE stations, and a review and revision of existing OSPE stations through intensive focus group discussions. Face and content validity was established by subject nonexperts and experts, respectively...
July 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/29290247/can-we-do-that-here-establishing-the-scope-of-surgical-practice-at-a-new-safety-net-community-hospital-through-a-transparent-collaborative-review-of-physician-privileges
#7
Sean M O'Neill, Sarah Seresinghe, Arun Sharma, Tara A Russell, L'Orangerie Crawford, Stanley K Frencher
PROBLEM DEFINITION: Stewarding of physician privileges wisely is imperative, but no guidelines exist for how to incorporate system-level factors in privileging decisions. A newly opened, safety-net community hospital tailored the scope of surgical practice through review of physician privileges. Martin Luther King, Jr. Community Hospital is a public-private partnership, safety-net institution in South Los Angeles that opened in July 2015. It has 131 beds, including a 28-bed emergency department, a 20-bed ICU, and 5 operating rooms...
January 2018: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29276327/critical-agentic-and-trans-media-frameworks-and-findings-from-a-foresight-analysis-exercise-on-audiences
#8
Ranjana Das, Brita Ytre-Arne
We write this article presenting frameworks and findings from an international network on audience research, as we stand 75 years from Herta Herzog's classic investigation of radio listeners, published in Lazarsfeld and Stanton's 1944 war edition of Radio Research. The article aims to contribute to and advance a rich strand of self-reflexive stock-taking and sorting of future research priorities within the transforming field of audience analysis, by drawing on the collective efforts of CEDAR - Consortium on Emerging Directions in Audience Research - a 14-country network (2015-2018) funded by the Arts and Humanities Research Council, United Kingdom, which conducted a foresight analysis exercise on developing current trends and future scenarios for audiences and audience research in the year 2030...
December 2017: European Journal of Communication
https://www.readbyqxmd.com/read/29248818/barriers-facilitators-and-potential-strategies-for-increasing-hpv-vaccination-a-statewide-assessment-to-inform-action
#9
Kathleen B Cartmell, Jennifer Young-Pierce, Shannon McGue, Anthony J Alberg, John S Luque, Maria Zubizarreta, Heather M Brandt
OBJECTIVE: The objective was to investigate how state level strategies in South Carolina could maximize HPV vaccine uptake. DESIGN: An environmental scan identified barriers, facilitators, and strategies for improving HPV vaccination in South Carolina. Interviews were conducted with state leaders from relevant organizations such as public health agencies, medical associations, K-12 schools, universities, insurers, and cancer advocacy organizations. A thematic content analysis design was used...
December 7, 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/29238450/american-telemedicine-association-s-principles-for-delivering-telerehabilitation-services
#10
Tammy Richmond, Christopher Peterson, Jana Cason, Mike Billings, Evelyn Abrahante Terrell, Alan Chong W Lee, Michael Towey, Bambang Parmanto, Andi Saptono, Ellen R Cohn, David Brennan
Telehealth is a broad term used to describe the use of electronic or digital information and communications technologies to support clinical healthcare, patient and professional health related education, and public health and health administration. Telerehabilitation refers to the delivery of rehabilitation and habilitation services via information and communication technologies (ICT), also commonly referred to as" telehealth" technologies. Telerehabilitation services can include evaluation, assessment, monitoring, prevention, intervention, supervision, education, consultation, and coaching...
2017: International Journal of Telerehabilitation
https://www.readbyqxmd.com/read/29237952/cancer-related-fatigue-treatment-an-overview
#11
REVIEW
Hemanth Mohandas, Saravana Kumar Jaganathan, Mohan Prasath Mani, Manikandan Ayyar, G V Rohini Thevi
Cancer-related fatigue is a symptom of cancer where most patients or the general practitioners tend to misinterpret due to the insufficient understanding or knowledge of cancer-related fatigue (CRF). This paper will provide a better perspective for the patients and the health professionals on how to manage and handle CRF for both mild and severe fatigue patients. Articles were selected from the searches of PubMed database that had the terms "randomized controlled trials," "cancer," "fatigue," "pharmacologic treatment," and "nonpharmacologic treatment" using both Mesh terms and keywords...
October 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29233448/introducing-problem-based-learning-into-a-canadian-accredited-middle-eastern-educational-setting
#12
Ziad G Nasr, Kyle John Wilby
BACKGROUND AND PURPOSE: Adaption of active learning strategies into new cultures and contexts requires careful consideration to maximize effectiveness and meet intended objectives. The aim of this paper was to describe the adaption and implementation of problem-based learning (PBL) within a pharmacy curriculum in a Middle Eastern context. EDUCATIONAL ACTIVITY AND SETTING: PBL was implemented into the curriculum at Qatar University in 2014 and expanded in subsequent years to include differing courses and contexts...
July 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29173282/using-bioinformatics-to-treat-hospitalized-smokers-successes-and-challenges-of-a-tobacco-treatment-service
#13
Thomas Ylioja, Vivek Reddy, Richard Ambrosino, Esa M Davis, Antoine Douaihy, Kristin Slovenkay, Valerie Kogut, Beth Frenak, Kathy Palombo, Anna Schulze, Gerald Cochran, Hilary A Tindle
BACKGROUND: Hospitals face increasing regulations to provide and document inpatient tobacco treatment, yet few blueprint data exist to implement a tobacco treatment service (TTS). METHODS: A hospitalwide, opt-out TTS with three full-time certified counselors was developed in a large tertiary care hospital to proactively treat smokers according to Chronic Care Model principles and national treatment guidelines. A bioinformatics platform facilitated integration into the electronic health record to meet evolving Centers for Medicare & Medicaid Services meaningful use and Joint Commission standards...
December 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29126204/proteomic-analysis-of-germinal-vesicles-in-the-domestic-cat-model-reveals-candidate-nuclear-proteins-involved-in-oocyte-competence-acquisition
#14
P-C Lee, D E Wildt, P Comizzoli
STUDY QUESTION: Do nuclear proteins in the germinal vesicle (GV) contribute to oocyte competence acquisition during folliculogenesis? SUMMARY ANSWER: Proteomic analysis of GVs identified candidate proteins for oocyte competence acquisition, including a key RNA processing protein - heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1). WHAT IS KNOWN ALREADY: The domestic cat GV, which is physiologically similar to the human GV, gains the intrinsic ability to resume meiosis and support early embryo development during the pre-antral-to-antral follicle transition...
November 8, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29124548/development-of-an-experimental-and-digital-cardiovascular-arterial-model-for-transient-hemodynamic-and-postural-change-studies-a-preliminary-framework-analysis
#15
Rodward L Hewlin, John P Kizito
The ultimate goal of the present work is to aid in the development of tools to assist in the treatment of cardiovascular disease. Gaining an understanding of hemodynamic parameters for medical implants allow clinicians to have some patient-specific proposals for intervention planning. In the present work an experimental and digital computational fluid dynamics (CFD) arterial model consisting of a number of major arteries (aorta, carotid bifurcation, cranial, femoral, jejunal, and subclavian arteries) were fabricated to study: (1) the effects of local hemodynamics (flow parameters) on global hemodynamics (2) the effects of transition from bedrest to upright position (postural change) on hemodynamics, and (3) diffusion of dye (medical drug diffusion simulation) in the arterial system via experimental and numerical techniques...
November 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29101998/will-noninvasive-methods-surpass-invasive-for-assessing-gametes-and-embryos
#16
REVIEW
Tim Sanchez, Emily A Seidler, David K Gardner, Daniel Needleman, Denny Sakkas
The need to identify the most viable embryo following in vitro fertilization (IVF) was established early in the history of human IVF. The stalwart of identifying the best embryos has been morphology. Other techniques have however seen wide acceptance, including the use of preimplantation genetic screening, even though concerns exist over the invasive nature of the technique. Alternatively, noninvasive assessment technologies have tried to determine an embryo's viability through measurements of factors in the media or by imaging of the embryo...
November 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29101426/the-city-blueprint-approach-urban-water-management-and-governance-in-cities-in-the-u-s
#17
Daniel Feingold, Stef Koop, Kees van Leeuwen
In this paper, we assess the challenges of water, waste and climate change in six cities across the U.S.: New York City, Boston, Milwaukee, Phoenix, Portland and Los Angeles. We apply the City Blueprint(®) Approach which consists of three indicator assessments: (1) the Trends and Pressures Framework (TPF), (2) the City Blueprint Framework (CBF) and (3) the water Governance Capacity Framework (GCF). The TPF summarizes the main social, environmental and financial pressures that may impede water management. The CBF provides an integrated overview of the management performances within the urban watercycle...
November 3, 2017: Environmental Management
https://www.readbyqxmd.com/read/29055891/using-an-alumni-survey-to-target-improvements-in-an-emergency-medicine-training-programme
#18
Theodore Gaeta, Gowtham Mahalingam, Matthew Pyle, Aaron Dam, Annette Visconti
INTRODUCTION: The Accreditation Council for Graduate Medical Education (ACGME) is the governing body responsible for accrediting graduate medical training programme in the USA. The Emergency Medicine Milestones (EM-Milestones) were developed by the ACGME and American Board of Emergency Medicine as a guide and monitoring tool for the knowledge, skills, abilities and experiences to be acquired during training. Alumni surveys have been reported as a valuable resource for training programme to identify areas for improvement; however, there are few studies regarding programme improvement in emergency medicine...
October 21, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29025429/updated-clinical-guidelines-experience-major-reporting-limitations
#19
Robin W M Vernooij, Laura Martínez García, Ivan Dario Florez, Laura Hildago Armas, Michiel H F Poorthuis, Melissa Brouwers, Pablo Alonso-Coello
BACKGROUND: The Checklist for the Reporting of Updated Guidelines (CheckUp) was recently developed. However, so far, no systematic assessment of the reporting of updated clinical guidelines (CGs) exists. We aimed to examine (1) the completeness of reporting the updating process in CGs and (2) the inter-observer reliability of CheckUp. METHODS: We conducted a systematic assessment of the reporting of the updating process in a sample of updated CGs using CheckUp. We performed a systematic search to identify updated CGs published in 2015, developed by a professional society, reporting a systematic review of the evidence, and containing at least one recommendation...
October 12, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28961150/the-use-of-differential-item-functioning-dif-analysis-to-distinguish-between-similar-job-roles
#20
Nicole M Risk, James R Fidler
Two primary roles in the clinical laboratory are those of Medical Technologist (MT) and Medical Laboratory Technician (MLT). Job analyses, which form the foundation of test blueprints employed for credentialing practitioners, suggest a reasonable amount of overlap in the tasks performed by MTs and MLTs. However, credentialing assessments must clearly distinguish between the two roles and ensure that they address competencies appropriate to each practice designation. Differential item functioning (DIF) analysis techniques were applied to explore and differentiate the two laboratory practitioner job roles as an aspect of examination development...
2017: Journal of Applied Measurement
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