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Blueprinting and assessment

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https://www.readbyqxmd.com/read/29233448/introducing-problem-based-learning-into-a-canadian-accredited-middle-eastern-educational-setting
#1
Ziad G Nasr, Kyle John Wilby
BACKGROUND AND PURPOSE: Adaption of active learning strategies into new cultures and contexts requires careful consideration to maximize effectiveness and meet intended objectives. The aim of this paper was to describe the adaption and implementation of problem-based learning (PBL) within a pharmacy curriculum in a Middle Eastern context. EDUCATIONAL ACTIVITY AND SETTING: PBL was implemented into the curriculum at Qatar University in 2014 and expanded in subsequent years to include differing courses and contexts...
July 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29173282/using-bioinformatics-to-treat-hospitalized-smokers-successes-and-challenges-of-a-tobacco-treatment-service
#2
Thomas Ylioja, Vivek Reddy, Richard Ambrosino, Esa M Davis, Antoine Douaihy, Kristin Slovenkay, Valerie Kogut, Beth Frenak, Kathy Palombo, Anna Schulze, Gerald Cochran, Hilary A Tindle
BACKGROUND: Hospitals face increasing regulations to provide and document inpatient tobacco treatment, yet few blueprint data exist to implement a tobacco treatment service (TTS). METHODS: A hospitalwide, opt-out TTS with three full-time certified counselors was developed in a large tertiary care hospital to proactively treat smokers according to Chronic Care Model principles and national treatment guidelines. A bioinformatics platform facilitated integration into the electronic health record to meet evolving Centers for Medicare & Medicaid Services meaningful use and Joint Commission standards...
December 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29126204/proteomic-analysis-of-germinal-vesicles-in-the-domestic-cat-model-reveals-candidate-nuclear-proteins-involved-in-oocyte-competence-acquisition
#3
P-C Lee, D E Wildt, P Comizzoli
STUDY QUESTION: Do nuclear proteins in the germinal vesicle (GV) contribute to oocyte competence acquisition during folliculogenesis? SUMMARY ANSWER: Proteomic analysis of GVs identified candidate proteins for oocyte competence acquisition, including a key RNA processing protein - heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1). WHAT IS KNOWN ALREADY: The domestic cat GV, which is physiologically similar to the human GV, gains the intrinsic ability to resume meiosis and support early embryo development during the pre-antral-to-antral follicle transition...
November 8, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29124548/development-of-an-experimental-and-digital-cardiovascular-arterial-model-for-transient-hemodynamic-and-postural-change-studies-a-preliminary-framework-analysis
#4
Rodward L Hewlin, John P Kizito
The ultimate goal of the present work is to aid in the development of tools to assist in the treatment of cardiovascular disease. Gaining an understanding of hemodynamic parameters for medical implants allow clinicians to have some patient-specific proposals for intervention planning. In the present work an experimental and digital computational fluid dynamics (CFD) arterial model consisting of a number of major arteries (aorta, carotid bifurcation, cranial, femoral, jejunal, and subclavian arteries) were fabricated to study: (1) the effects of local hemodynamics (flow parameters) on global hemodynamics (2) the effects of transition from bedrest to upright position (postural change) on hemodynamics, and (3) diffusion of dye (medical drug diffusion simulation) in the arterial system via experimental and numerical techniques...
November 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29101998/will-noninvasive-methods-surpass-invasive-for-assessing-gametes-and-embryos
#5
REVIEW
Tim Sanchez, Emily A Seidler, David K Gardner, Daniel Needleman, Denny Sakkas
The need to identify the most viable embryo following in vitro fertilization (IVF) was established early in the history of human IVF. The stalwart of identifying the best embryos has been morphology. Other techniques have however seen wide acceptance, including the use of preimplantation genetic screening, even though concerns exist over the invasive nature of the technique. Alternatively, noninvasive assessment technologies have tried to determine an embryo's viability through measurements of factors in the media or by imaging of the embryo...
November 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29101426/the-city-blueprint-approach-urban-water-management-and-governance-in-cities-in-the-u-s
#6
Daniel Feingold, Stef Koop, Kees van Leeuwen
In this paper, we assess the challenges of water, waste and climate change in six cities across the U.S.: New York City, Boston, Milwaukee, Phoenix, Portland and Los Angeles. We apply the City Blueprint(®) Approach which consists of three indicator assessments: (1) the Trends and Pressures Framework (TPF), (2) the City Blueprint Framework (CBF) and (3) the water Governance Capacity Framework (GCF). The TPF summarizes the main social, environmental and financial pressures that may impede water management. The CBF provides an integrated overview of the management performances within the urban watercycle...
November 3, 2017: Environmental Management
https://www.readbyqxmd.com/read/29055891/using-an-alumni-survey-to-target-improvements-in-an-emergency-medicine-training-programme
#7
Theodore Gaeta, Gowtham Mahalingam, Matthew Pyle, Aaron Dam, Annette Visconti
INTRODUCTION: The Accreditation Council for Graduate Medical Education (ACGME) is the governing body responsible for accrediting graduate medical training programme in the USA. The Emergency Medicine Milestones (EM-Milestones) were developed by the ACGME and American Board of Emergency Medicine as a guide and monitoring tool for the knowledge, skills, abilities and experiences to be acquired during training. Alumni surveys have been reported as a valuable resource for training programme to identify areas for improvement; however, there are few studies regarding programme improvement in emergency medicine...
October 21, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29025429/updated-clinical-guidelines-experience-major-reporting-limitations
#8
Robin W M Vernooij, Laura Martínez García, Ivan Dario Florez, Laura Hildago Armas, Michiel H F Poorthuis, Melissa Brouwers, Pablo Alonso-Coello
BACKGROUND: The Checklist for the Reporting of Updated Guidelines (CheckUp) was recently developed. However, so far, no systematic assessment of the reporting of updated clinical guidelines (CGs) exists. We aimed to examine (1) the completeness of reporting the updating process in CGs and (2) the inter-observer reliability of CheckUp. METHODS: We conducted a systematic assessment of the reporting of the updating process in a sample of updated CGs using CheckUp. We performed a systematic search to identify updated CGs published in 2015, developed by a professional society, reporting a systematic review of the evidence, and containing at least one recommendation...
October 12, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28961150/the-use-of-differential-item-functioning-dif-analysis-to-distinguish-between-similar-job-roles
#9
Nicole M Risk, James R Fidler
Two primary roles in the clinical laboratory are those of Medical Technologist (MT) and Medical Laboratory Technician (MLT). Job analyses, which form the foundation of test blueprints employed for credentialing practitioners, suggest a reasonable amount of overlap in the tasks performed by MTs and MLTs. However, credentialing assessments must clearly distinguish between the two roles and ensure that they address competencies appropriate to each practice designation. Differential item functioning (DIF) analysis techniques were applied to explore and differentiate the two laboratory practitioner job roles as an aspect of examination development...
2017: Journal of Applied Measurement
https://www.readbyqxmd.com/read/28935377/assessment-of-carbon-footprint-emissions-and-environmental-concerns-of-solid-waste-treatment-and-disposal-techniques-case-study-of-malaysia
#10
Amirhossein Malakahmad, Motasem S Abualqumboz, Shamsul Rahman M Kutty, Taher J Abunama
Malaysian authorities has planned to minimize and stop when applicable unsanitary dumping of waste as it puts human health and the environment at elevated risk. Cost, energy and revenue are mostly adopted to draw the blueprint of upgrading municipal solid waste management system, while the carbon footprint emissions criterion rarely acts asa crucial factor. This study aims to alert Malaysian stakeholders on the uneven danger of carbon footprint emissions of waste technologies. Hence, three scenarios have been proposed and assessed mainly on the carbon footprint emissions using the 2006 IPCC methodology...
September 18, 2017: Waste Management
https://www.readbyqxmd.com/read/28929359/immunohistochemical-versus-molecular-blueprint-and-mammaprint-subtyping-of-breast-carcinoma-outcome-results-from-the-eortc-10041-big-3-04-mindact-trial
#11
G Viale, F A de Snoo, L Slaets, J Bogaerts, L van 't Veer, E J Rutgers, M J Piccart-Gebhart, L Stork-Sloots, A Glas, L Russo, P Dell'Orto, K Tryfonidis, S Litière, F Cardoso
PURPOSE: This study compares immunohistochemical (IHC) versus molecular subtyping (BluePrint and MammaPrint) in the population of patients enrolled in MINDACT and outcome based on molecular subtyping (MS) versus surrogate pathological subtyping (PS) as defined by the 2013 St. Gallen guidelines. METHODS: MS classified patients in the following subtypes: Luminal A, Luminal B, HER-2-, and Basal-type. IHC/FISH for pathological subtyping (ER, PgR, HER-2, and Ki67) was centrally assessed in the European Institute of Oncology (n = 5806)...
September 19, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28864267/developing-the-blueprint-for-a-general-surgery-technical-skills-certification-examination-a-validation-study
#12
Sandra de Montbrun, Marisa Louridas, Peter Szasz, Kenneth A Harris, Teodor P Grantcharov
INTRODUCTION: There is a recognized need to develop high-stakes technical skills assessments for decisions of certification and resident promotion. High-stakes examinations requires a rigorous approach in accruing validity evidence throughout the developmental process. One of the first steps in development is the creation of a blueprint which outlines the potential content of examination. The purpose of this validation study was to develop an examination blueprint for a Canadian General Surgery assessment of technical skill certifying examination...
August 29, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28841874/science-of-health-care-delivery-milestones-for-undergraduate-medical-education
#13
Rachel D Havyer, Suzanne M Norby, Andrea N Leep Hunderfund, Stephanie R Starr, Tara R Lang, Alexandra P Wolanskyj, Darcy A Reed
BACKGROUND: The changing healthcare landscape requires physicians to develop new knowledge and skills such as high-value care, systems improvement, population health, and team-based care, which together may be referred to as the Science of Health Care Delivery (SHCD). To engender public trust and confidence, educators must be able to meaningfully assess physicians' abilities in SHCD. We aimed to develop a novel set of SHCD milestones based on published Accreditation Council for Graduate Medical Education (ACGME) milestones that can be used by medical schools to assess medical students' competence in SHCD...
August 25, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28811044/learning-how-to-teach-one-a-needs-assessment-of-the-state-of-faculty-development-within-the-consortium-of-the-american-college-of-surgeons-accredited-education-institutes
#14
John T Paige, Nehal N Khamis, Jeffrey B Cooper
BACKGROUND: Developing faculty competencies in curriculum development, teaching, and assessment using simulation is critical for the success of the Consortium of the American College of Surgeons Accredited Education Institutes program. The state of and needs for faculty development in the Accredited Education Institute community are unknown currently. The Faculty Development Committee of the Consortium of the Accredited Education Institutes conducted a survey of Accredited Education Institutes to ascertain what types of practices are used currently, with what frequency, and what needs are perceived for further programs and courses to guide the plan of action for the Faculty Development Committee...
November 2017: Surgery
https://www.readbyqxmd.com/read/28800089/fitnet-s-internet-based-cognitive-behavioural-therapy-is-ineffective-and-may-impede-natural-recovery-in-adolescents-with-myalgic-encephalomyelitis-chronic-fatigue-syndrome-a-review
#15
REVIEW
Simin Ghatineh, Mark Vink
The Dutch Fatigue In Teenagers on the interNET (FITNET) study claimed that after 6 months, internet based cognitive behaviour therapy in adolescents with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), led to a 63% recovery rate compared to 8% after usual care, and that this was maintained at long term follow up (LTFU). Our reanalysis shows that their post-hoc definition of recovery included the severely ill, the unblinded trial had no adequate control group and it used lax selection criteria as well as outcomes assessed via questionnaires rather than objective outcomes, further contributing to exaggerated recovery figures...
August 11, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28757337/differentiating-physicochemical-properties-between-ndris-and-snris-clinically-important-for-the-treatment-of-adhd
#16
Panpan Wang, Tingting Fu, Xiaoyu Zhang, Fengyuan Yang, Guoxun Zheng, Weiwei Xue, Yuzong Chen, Xiaojun Yao, Feng Zhu
BACKGROUND: Drugs available for treating attention-deficit hyperactivity disorder (ADHD) are mainly selective norepinephrine (sNRIs) and dual norepinephrine-dopamine (NDRIs) reuptake inhibitors. The major problem of sNRIs lines in their delayed onset of action and partial- or non-responses, which makes NDRIs distinguished in drug efficacy. Understanding of the differential binding modes of these 2 types of drugs to their corresponding targets can give great insights into the discovery of privileged drug-like scaffolds with improved efficacy...
November 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28690856/it-supported-integrated-care-pathways-for-diabetes-a-compilation-and-review-of-good-practices
#17
Hubertus Jm Vrijhoef, Antonio Giulio de Belvis, Matias de la Calle, Maria Stella de Sabata, Bastian Hauck, Sabrina Montante, Annette Moritz, Dario Pelizzola, Markku Saraheimo, Nick A Guldemond
INTRODUCTION: Integrated Care Pathways (ICPs) are a method for the mutual decision-making and organization of care for a well-defined group of patients during a well-defined period. The aim of a care pathway is to enhance the quality of care by improving patient outcomes, promoting patient safety, increasing patient satisfaction, and optimizing the use of resources. To describe this concept, different names are used, e.g. care pathways and integrated care pathways. Modern information technologies (IT) can support ICPs by enabling patient empowerment, better management, and the monitoring of care provided by multidisciplinary teams...
June 2017: International Journal of Care Coordination
https://www.readbyqxmd.com/read/28675542/white-matter-maturation-in-the-neonatal-brain-is-predictive-of-school-age-cognitive-capacities-in-children-born-very-preterm
#18
Kristin Keunen, Manon J Benders, Alexander Leemans, Petronella C Fieret-Van Stam, Lianne H Scholtens, Max A Viergever, René S Kahn, Floris Groenendaal, Linda S de Vries, Martijn P van den Heuvel
AIM: To investigate the association between white matter organization in the neonatal brain and cognitive capacities at early school age in children born very preterm. METHOD: Thirty children born very preterm (gestational age median 27.5wks, interquartile range [IQR] 25.5-29.5; 18 males, 12 females) were included in this retrospective observational cohort study. Diffusion-weighted imaging (DWI) had been performed on a 3T system in the neonatal period (median 41...
September 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28675202/natural-product-analogues-towards-a-blueprint-for-analogue-focused-synthesis
#19
REVIEW
Magnus W P Bebbington
For the first time a general overview of approaches to the synthesis of natural product analogues is presented. This reflects a process of evolution of natural product synthesis which has accelerated in the years since the implementation of diversity-oriented synthesis, which has emerged in parallel with collective synthesis, diverted total synthesis and the preparation of truncated natural products optimised for biological activity. A method involving computational assessment for the validation of core-modified natural product analogues is discussed...
August 14, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28671715/the-critically-endangered-western-chimpanzee-declines-by-80
#20
Hjalmar S Kühl, Tenekwetche Sop, Elizabeth A Williamson, Roger Mundry, David Brugière, Genevieve Campbell, Heather Cohen, Emmanuel Danquah, Laura Ginn, Ilka Herbinger, Sorrel Jones, Jessica Junker, Rebecca Kormos, Celestin Y Kouakou, Paul K N'Goran, Emma Normand, Kathryn Shutt-Phillips, Alexander Tickle, Elleni Vendras, Adam Welsh, Erin G Wessling, Christophe Boesch
African large mammals are under extreme pressure from unsustainable hunting and habitat loss. Certain traits make large mammals particularly vulnerable. These include late age at first reproduction, long inter-birth intervals, and low population density. Great apes are a prime example of such vulnerability, exhibiting all of these traits. Here we assess the rate of population change for the western chimpanzee, Pan troglodytes verus, over a 24-year period. As a proxy for change in abundance, we used transect nest count data from 20 different sites archived in the IUCN SSC A...
September 2017: American Journal of Primatology
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