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Rhinitis management

Maureen Egan, Dan Atkins
PURPOSE OF REVIEW: Observations suggesting that aeroallergens trigger eosinophilic esophagitis (EoE) in a subset of patients raise questions about the implications this finding has on the evaluation and management of patients with EoE, including a potential role for allergen immunotherapy. RECENT FINDINGS: The majority of studies evaluating the potential role of aeroallergens as provocateurs of EoE have addressed this issue by assessing the seasonal variation in EoE diagnosis and/or symptom onset or worsening, with mixed results...
June 16, 2018: Current Allergy and Asthma Reports
Paloma Campo, Ibon Eguiluz-Gracia, Gador Bogas, María Salas, Carmen Plaza Serón, Natalia Pérez, C Mayorga, M J Torres, Mohammed Shamji, Carmen Rondon
A significant proportion of rhinitis patients without systemic IgE-sensitization tested by skin prick test and serum allergen-specific IgE (sIgE) display nasal reactivity upon nasal allergen provocation test (NAPT). This disease phenotype has been termed local allergic rhinitis (LAR). LAR is an underdiagnosed entity affecting children and adults from different parts of the world, with moderate-to-severe symptoms, impairment of quality of life and rapid progression to symptom worsening. LAR is a stable phenotype and not merely an initial state of AR...
June 14, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Yichen Xiao, Wenna Xu, Wenru Su
Allergic diseases, such as asthma, rhinitis, dermatitis, conjunctivitis, and anaphylaxis, have recently become a global public health concern. According to previous studies, the NLRP3 inflammasome is a multi-protein complex known to be associated with many inflammatory conditions. In response to allergens or allergen/damage-associated molecular signals, NLRP3 changes its conformation to allow the assembly of the NLRP3 inflammasome complex and activates caspase-1, which is an evolutionarily conserved enzyme that proteolytically cleaves other proteins, such as the precursors of the inflammatory cytokines IL-1β and IL-18...
June 13, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Yongqiang Zhao, X Ma, Y Li, Q Fu
OBJECTIVES: As part of the UN peacekeeping mission in Mali, the People's Republic of China have deployed a level 2 medical treatment facility (CHN L2). The aim of this study was to review the cases managed by the otolaryngology service within this facility. METHODS: The medical records of all patients treated by the otolaryngology service at the CHN L2 from 1 March 2015 to 1 March 2018 were retrospectively assessed. RESULTS: 614/10189 (6%) of all cases seen in the hospital during this period were referred to the otolaryngology service...
June 11, 2018: Journal of the Royal Army Medical Corps
Rongfei Zhu, Jingru Wang, Yuying Wu, Yongshi Yang, Nan Huang, Yaqi Yang, Rui Zhang, Dongxia Ma, Lin Yang, Pascal Demoly
BACKGROUND: Allergic Rhinitis Control Test(ARCT) has been validated in allergic rhinitis(AR) step-up pharmacotherapy management approach. OBJECTIVE: The aim of our study was to evaluate the potential of ARCT in AR step-down pharmacotherapy. METHODS: In an open-labelled randomized controlled study, AR patients controlled with intranasal corticosteroid(INS) plus antihistamine(step 4) were included and randomized into an ARCT or a control group...
June 7, 2018: Journal of Allergy and Clinical Immunology in Practice
Anthony Ca Yii, Tunn-Ren Tay, Xue Ning Choo, Mariko Sy Koh, Augustine Kh Tee, De-Yun Wang
United airways disease (UAD) is the concept that the upper and lower airways, which are anatomically and immunologically related, form a single organ. According to this concept, upper and lower airway diseases are frequently comorbid because they reflect manifestations of a single underlying disease at different sites of the respiratory tract. Allergic asthma-allergic rhinitis is the archetypal UAD, but emerging data indicate that UAD is a heterogeneous condition and consists of multiple phenotypes (observable clinical characteristics) and endotypes (pathobiologic mechanisms)...
June 5, 2018: Allergy
Amy Huang, Christine Cho, Donald Y M Leung, Kanwaljit Brar
Therapeutic regimens for the treatment and long-term management of AD traditionally had a two-fold objective of decreasing skin inflammation and repairing the defective skin barrier. Essential treatments for AD in children should include topical moisturizers for skin hydration and prevention of flares, topical anti-inflammatory medications (e.g. corticosteroids, calcineurin inhibitors, PDE4 inhibitor), allergen/irritant avoidance, and treatment of skin infections. Treatment regimens should be severity-based, and implemented in a stepwise approach tailored to the individual patient...
September 2017: Current Treatment Options in Allergy
Carmen Rondón, Ibon Eguiluz-Gracia, Paloma Campo
PURPOSE OF REVIEW: To examine the recent advances on epidemiological studies, diagnostic approach and clinical management of local allergic rhinitis (LAR) in adults and children. RECENT FINDINGS: Evidence about LAR is growing especially in pediatric and Asian populations. The prevalence of LAR is lower in Asian countries compared with western countries in both children and adults. LAR is considered a chronic condition and an independent rhinitis phenotype that affects up to 26...
May 29, 2018: Current Opinion in Allergy and Clinical Immunology
Suresh Mohan, Jennifer C Fuller, Stephanie Friree Ford, Robin W Lindsay
Importance: Nasal airway obstruction (NAO) is a common complaint in the otolaryngologist's office and can have a negative influence on quality of life (QOL). Existing diagnostic methods have improved, but little consensus exists on optimal tools. Furthermore, although surgical techniques for nasal obstruction continue to be developed, effective outcome measurement is lacking. An update of recent advances in diagnostic and therapeutic management of NAO is warranted. Objective: To review advances in diagnosis and treatment of NAO from the last 5 years...
May 10, 2018: JAMA Facial Plastic Surgery
Z Z Cao, X X Zheng, B H Feng, J J Gao, S Y Huang, X Zhan, B L Li, B B Chen
Objective: To investigate the association between symptom of attention deficit/hyperactivity disorder (ADHD) and allergic rhinitis (AR) in children with AR at different sexes and different ages. Method: A total of 439 AR children aged 6 to 12 years were enrolled in this study. Basic information (age, gender, medical history, family history and comorbidities) of children with AR was collected. Results of prick tests on children skin were recorded. (TNSS) and Chinese version of the SNAP-Ⅳ scale, children under the guidance of independent completion of children's quality of life of children with nasal conjunctivitis scale (PRQLQ)...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y Qiao, T Liu, K J Zhang, Y Feng, Y Liu, K T Li
Objective: To observe the auxiliary curative effect of combined clostridium and bifidobacterium capsules, live (also called Changlekang) in the treatment of allergic rhinitis by comparing IL-10, transforming growth factor-β1(TGF-β1), the quality of life score and symptom score before and after oral Changlekang. Method: Twenty qualified patients in the study group and 20 qualified patients in the control group were enrolled.The study group was given changlekang, desloratadine citrate disodium tablets and mometasone furoate nasal spray for treatment...
September 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
C Q Zheng
No abstract text is available yet for this article.
September 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
X P Wu, R Q Qiu, X F Yang, K Shen, S T Tian
Objective: To investigate the influence on compliance of sublingual immunotherapy (SLIT) in patients with allergic rhinitis by We-Media management. Method: One hundred and eighty patients of allergic rhinitis were randomly divided into We-Media management group (Group A 90 cases) and telephone management group (Group B 90 cases). All of patients were treated with SLIT. In the group A, the doctor-patient WeChat and/or QQ group were formed. The specific duty doctor acted as group leader, made monthly plans, sent SLIT related knowledge more than 3 times a week and assessed patient reported outcomes...
April 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Hesham Tarraf, Omur Aydin, Dilsad Mungan, Mohammad Albader, Bassam Mahboub, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz, Abdelkader El Hasnaoui
BACKGROUND: Asthma is a common chronic respiratory disease leading to morbidity, mortality and impaired quality of life worldwide. Information on asthma prevalence in the Middle East is fragmented and relatively out-dated. The SNAPSHOT program was conducted to obtain updated information. METHODS: SNAPSHOT is a cross-sectional epidemiological program carried out in five Middle Eastern countries (Egypt, Turkey, Kuwait, Saudi Arabia, and the United Arab Emirates, the latter three grouped into a Gulf cluster) to collect data on asthma, allergic rhinitis, benign prostatic hyperplasia and bipolar disorder...
May 11, 2018: BMC Pulmonary Medicine
Alyssa Oland, Genery D Booster, Bruce G Bender
OBJECTIVE: The present article will review current findings regarding the management of stress in allergic disease. DATA SOURCES: The present review article uses articles and books published between 1995 and 2017. Approximately 85% of sources used were published in the last 10 years and 60% were published in the last 5 years. The majority of sources are peer-reviewed articles. STUDY SELECTIONS: Articles that focused on allergic diseases such as allergic rhinitis, food allergies, urticaria, and allergic asthma were included in the present review...
May 8, 2018: Annals of Allergy, Asthma & Immunology
Marcus Shaker, Robert G P Murray, Julianne A Mann
PURPOSE OF REVIEW: The skin barrier is a dynamic innate immune organ. This review summarizes the current understanding of how deficiencies associated with atopic dermatitis invite other atopic disorders of the allergic march. RECENT FINDINGS: Atopic dermatitis is characterized by skin barrier defects (such as mutations in filaggrin), intrinsic proallergic T-helper cell 2 immune dysregulation, and skin microbiome alterations. These factors promote the development of food allergy and asthma...
May 9, 2018: Current Opinion in Pediatrics
Sungjin Park, Pil Kyun Jung, Myungsup Choi, Hongdeok Seok, Hansol Kim, Sung-Soo Oh, Sang-Baek Koh
OBJECTIVES: This study aimed to investigate the association between occupational clusters and allergic rhinitis (AR). METHODS: The study was based on data from the Korean National Health and Nutrition Examination Survey (KNHANES: 2007-2015). This study included 46,965 individuals: 20,491 men and 26,474 women. AR was defined as having been diagnosed by a physician. Occupations were classified according to occupational characteristics and skill levels into white (chief executives, senior officials, legislators, managers, professionals, and technicians), pink (clerks, clerical support workers, services and sales workers), blue (craft and related trades workers, drivers, plant and machine operators, assemblers, elementary occupation workers), and green (skilled agricultural, forestry, and fishery workers) categories...
May 9, 2018: Journal of Occupational Health
Victoria Rojas-Mandujano, Kitzia González-Juárez, Cecilia Hernández-Fernández, Patricia María O'Farrill-Romanillos, Leonel Del Rivero, Diana Andrea Herrera-Sánchez
BACKGROUND: Latex-fruit syndrome (LFS) is characterized by allergy to latex and plants. Papain, chymopapain, caricaine and class I chitinases are papaya's most allergenic proteins. The similarity between latex hevein epitopes and papaya class I chitinases might explain the latex-papaya syndrome (LPS). OBJECTIVE: To describe the clinical characteristics of patients with LPS. METHODS: Cross-sectional, observational, descriptive study where 11 patients diagnosed with latex allergy by skin prick test and clinically diagnosed with papaya-induced anaphylaxis were included...
January 2018: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
David W Hsu, Jeffrey D Suh
Rhinitis and sinusitis are common medical conditions that affect the geriatric population and have a significant impact on their quality of life. Because few studies examine differences in the clinical management between the geriatric and general adult population, therapies should be based on current guidelines. Special considerations should be made when treating these patients in regards to multiple comorbidities and the potential for drug interactions from polypharmacy. Further research on the pathogenesis of sinusitis in the geriatric population may provide specific differences in the clinical management in this population...
April 18, 2018: Otolaryngologic Clinics of North America
R Jankowski, P Gallet, D T Nguyen, C Rumeau
The clinical distinction of chronic respiratory rhinitis appears to confirm the evo-devo theory of the three noses. The authors report two cases of advanced allergic rhinitis, in which chronic inflammation had induced a violaceous colour of the mucosa of the respiratory nose and a whitish polypoid appearance of the free edge of the middle turbinate. Nose and paranasal sinus CT scan revealed, beyond the virtual nasal cavities observed on nasal endoscopy and CT imaging, normal radiolucency or only minor opacities of the ethmoid (i...
April 17, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
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