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Junxue Zhou, Sha Li, Gaozhong Nie, Xiwei Fan, Jinxian Tan, Huayue Li, Xiaoke Pang
With the booming development of evacuation simulation software, developing an extensive database in indoor scenarios for evacuation models is imperative. In this paper, we conduct a qualitative and quantitative analysis of the collected videotapes and aim to provide a complete and unitary database of pedestrians' earthquake emergency response behaviors in indoor scenarios, including human-environment interactions. Using the qualitative analysis method, we extract keyword groups and keywords that code the response modes of pedestrians and construct a general decision flowchart using chronological organization...
2018: PloS One
Charkarra Anderson-Lewis, Gabrielle Darville, Rebeccah Eve Mercado, Savannah Howell, Samantha Di Maggio
BACKGROUND: The proportion of people in the United States who are members of at least two ethnic groups is projected to increase to 10% by the year 2050. This makes addressing health disparities and health inequities in minority populations increasingly more difficult. Minority populations, including those who classify themselves as African American and Hispanic, are using mobile phones to access health information via the internet more frequently than those who classify themselves as white, providing unique opportunities for those in public health and health education to reach these traditionally underserved populations using mobile health (mHealth) interventions...
June 18, 2018: JMIR MHealth and UHealth
Nurudeen Olalekan Oloso, Shamsudeen Fagbo, Musa Garbati, Steve O Olonitola, Emmanuel Jolaoluwa Awosanya, Mabel Kamweli Aworh, Helen Adamu, Ismail Ayoade Odetokun, Folorunso Oludayo Fasina
Antimicrobial resistance (AMR) has emerged as a global health threat, which has elicited a high-level political declaration at the United Nations General Assembly, 2016. In response, member countries agreed to pay greater attention to the surveillance and implementation of antimicrobial stewardship. The Nigeria Centre for Disease Control called for a review of AMR in Nigeria using a “One Health approach”. As anecdotal evidence suggests that food animal health and production rely heavily on antimicrobials, it becomes imperative to understand AMR trends in food animals and the environment...
June 17, 2018: International Journal of Environmental Research and Public Health
Lucia Ruggiero, Fiore Manganelli, Lucio Santoro
PURPOSE OF REVIEW: Muscle pain syndromes are extremely frequent cause of chronic disability, and a muscle biopsy is often performed to achieve a diagnosis when myalgia has a myopatic origin. Instead, the role of muscle biopsy in fibromyalgia is controversial. This review examines the reported studies with the objective to evaluate if some changes exist in the muscle, if these changes produce pain and if muscle biopsy is helpful in diagnostic flowchart of fibromyalgia. RECENT FINDINGS: Recent studies focused on functional side (muscle metabolism and the altered expression of proteins) hypothesize the role of peripheral factors in the maintenance of chronic pain...
June 15, 2018: Current Opinion in Supportive and Palliative Care
Olivia Kimber, Jennifer G Cromley, Katherine L Molnar-Kimber
No abstract text is available yet for this article.
2018: Journal of Microbiology & Biology Education: JMBE
Wagner C S Magalhães, Nathalia M Araujo, Thiago P Leal, Gilderlanio S Araujo, Paula J S Viriato, Fernanda S Kehdy, Gustavo N Costa, Mauricio L Barreto, Bernardo L Horta, Maria Fernanda Lima-Costa, Alexandre C Pereira, Eduardo Tarazona-Santos, Maíra R Rodrigues
EPIGEN-Brazil is one of the largest Latin American initiatives at the interface of human genomics, public health, and computational biology. Here, we present two resources to address two challenges to the global dissemination of precision medicine and the development of the bioinformatics know-how to support it. To address the underrepresentation of non-European individuals in human genome diversity studies, we present the EPIGEN-5M+1KGP imputation panel-the fusion of the public 1000 Genomes Project (1KGP) Phase 3 imputation panel with haplotypes derived from the EPIGEN-5M data set (a product of the genotyping of 4...
June 14, 2018: Genome Research
Erivelton G Nepomuceno, Alípio M Barbosa, Marcos X Silva, Matjaž Perc
We present a theoretical approach to control bovine brucellosis. We have used individual-based modelling, which is a network-type alternative to compartmental models. Our model thus considers heterogeneous populations, and spatial aspects such as migration among herds and control actions described as pulse interventions are also easily implemented. We show that individual-based modelling reproduces the mean field behaviour of an equivalent compartmental model. Details of this process, as well as flowcharts, are provided to facilitate the reproduction of the presented results...
May 2018: Royal Society Open Science
Dan Turner, Frank M Ruemmele, Esther Orlanski-Meyer, Anne M Griffiths, Javier Martin de Carpi, Jiri Bronsky, Gabor Veres, Marina Aloi, Caterina Strisciuglio, Christian P Braegger, Amit Assa, Claudio Romano, Séamus Hussey, Michael Stanton, Mikko Pakarinen, Lissy de Ridder, Konstantinos H Katsanos, Nick Croft, Víctor Manuel Navas-López, David C Wilson, Sally Lawrence, Richard K Russell
BACKGROUND AND AIM: Acute severe colitis (ASC) is one of the few emergencies in paediatric gastroenterology. Tight monitoring and timely medical and surgical interventions may improve outcomes and minimize morbidity and mortality. We aimed to standardize daily treatment of ASC in children through detailed recommendations and practice points which are based on a systematic review of the literature and consensus of experts. METHODS: These guidelines are a joint effort of the European Crohn's and Colitis Organization (ECCO) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN)...
May 30, 2018: Journal of Pediatric Gastroenterology and Nutrition
Andrea Zanirato, Luca Cavagnaro, Marco Basso, Stefano Divano, Lamberto Felli, Matteo Formica
INTRODUCTION: Total knee arthroplasty revision (TKAr) is increasing of relevance in orthopaedic surgeon daily practice and will become more and more relevant in the future. The aim of this study is to summarize indications, complications, clinical and radiological mid-term results of metaphyseal sleeves in management of bone defects in TKAr. METHODS: A systematic review of English literature was performed on Medline. Retrospective or prospective studies with 2 years of follow-up (FU) were included...
May 29, 2018: Archives of Orthopaedic and Trauma Surgery
Kleanthis Simyrdanis, Nikos Papadopoulos, Pantelis Soupios, Stella Kirkou, Panagiotis Tsourlos
This work describes the efficiency and ability of Electrical Resistivity Tomography (ERT) to map and monitor the subsurface contamination caused by the wastes created during the production of olive oil. The spatial distribution and temporal variation of these wastes are investigated through an integrated methodological flowchart composed of numerical modeling tests and field data collected from an active waste disposal site. An Olive Oil Mills' Wastes (OOMW) real site was chosen to monitor the subsurface flow of the wastes that are disposed of in an artificial pond for 1...
May 14, 2018: Science of the Total Environment
Daniele Marrelli, Karol Polom, Alessandro Neri, Franco Roviello
Treatment options to gastric cancer (GC) have been changing in recent years from a standard to a tailored approach. Different individualized procedures can range from endoscopic resection, D2 with open or minimally invasive approach, to neo-adjuvant therapy followed by extended surgery. In more advanced stages, a combined approach with the inclusion of intraperitoneal chemo-hyperthermia (HIPEC) may represent a new advanced option. The inclusion of histological type according to Laurén classification in the flowchart of treatment could increase both accuracy and effectiveness of such tailored approach...
May 23, 2018: Updates in Surgery
Jorge Vásquez-Quiroga, Alvaro Taype-Rondan, Jessica Hanae Zafra-Tanaka, Ericson Arcana-López, Luis Cervera-Caballero, Javier Contreras-Turin, Katherine Guzmán-Cáceres, Juan Llatas-Perez, Luis Marin-Calderón, Alejandro Piscoya, Daniel Vargas-Blácido, Nelly Vásquez-Valverde, Raúl Timaná-Ruiz
OBJECTIVE: To provide evidence-based clinical recommendations for the evaluation and management of patients with upper gastrointestinal bleeding (UGB) in the Peruvian Social Security (EsSalud). MATERIALS AND METHODS: A local guideline development group (local GDG) was established, including specialists in gastroenterology and methodologists. The local GDG formulated 11 clinical questions to be answered by this clinical practice guide (CPG). We searched and selected CPG of UGB published from 2012, which answered the posed questions and obtained a score higher than 60% in domains 1 and 3 of the Appraisal of Guidelines for Research and Evaluation II (AGREE-II) tool...
January 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Sarah K West, Michael ʼShayʼ OʼMara, M Chance Spalding
BACKGROUND: Unplanned hospital readmissions are common across specialties. Descriptive readmission studies commonly query large administrative databases, which some speculate lack clinical granularity. This article provides the framework for a process improvement initiative aimed at identifying clinically meaningful reasons for trauma readmission. Our study hypothesizes an expected difference between the clinically abstracted reasons for readmission and those documented by the data processing staff in the trauma registry, and that those differences will be the starting point to target performance improvement...
April 30, 2018: Journal of Trauma and Acute Care Surgery
Kirk Waibel, Rachel Lee, Christopher Coop, Yun Mendoza, Kevin White
A diagnosis of food allergy adversely impacts one's ability to join or remain in the military. Inadequate knowledge or misconceptions of current military-specific standards regarding food allergy and how these apply to enlistment, induction, and retention in the United States military can potentially lead to inaccurate counseling as each military service has specific regulations which impact the evaluation and decision-making process. Recognizing this knowledge gap, the American Allergy, Asthma, and Immunology (AAAAI) Military Allergy and Immunology Assembly (MAIA) established a Work Group who reviewed and summarized all aspects of military instructions, policies, and regulations regarding IgE mediated food allergy...
May 16, 2018: Journal of Allergy and Clinical Immunology
Mona Mlika, Oumeima Lamzibri, Saoussen Bacha, Soumeya Laabidi, Chokri Haddouchi, Faouzi El Mezni
BACKGROUND: malignant pleural mesothelioma (MPM) is a rare tumor with a challenging diagnosis. Even if, clinical data are mandatory to suspect the diagnosis, the positive diagnosis is based on microscopic features. Morphologic features are still the port of call of the diagnosis but their non specific character and the multiplicity of differential diagnoses made the immunohistochemical markers mandatory for the diagnosis. Many antibodies with a positive diagnostic value including claretinin, mesothelin, WT1 and antibodies with a negative diagnostic value including TTF1, EMA, CD15 are recommended by the scientific societies...
May 14, 2018: Journal of Immunoassay & Immunochemistry
I Sebesta, B Stiburkova, J Krijt
Hereditary xanthinuria (type I) is caused by an inherited deficiency of the xanthine oxidorectase (XDH/XO), and is characterized by very low concentration of uric acid in blood and urine and high concentration of urinary xanthine, leading to urolithiasis. Type II results from a combined deficiency of XDH/XO and aldehyde oxidase. Patients present with hematuria, renal colic, urolithiasis or even acute renal failure. Clinical symptoms are the same for both types. In a third type, clinically distinct, sulfite oxidase activity is missing as well as XDH/XO and aldehyde oxidase...
May 3, 2018: Nucleosides, Nucleotides & Nucleic Acids
Lennart Weltje, Andreas Ufer, Mick Hamer, Peter Sowig, Sandra Demmig, Friedrich Dechet
Some amphibians occur in agricultural landscapes during certain periods of their life cycle and consequently might be exposed to plant protection products (PPPs). While the sensitivity of aquatic life-stages is considered to be covered by the standard assessment for aquatic organisms (especially fish), the situation is less clear for terrestrial amphibian life-stages. In this paper, considerations are presented on how a risk assessment for PPPs and terrestrial life-stages of amphibians could be conducted. It discusses available information concerning the toxicity of PPPs to terrestrial amphibians, and their potential exposure to PPPs in consideration of aspects of amphibian biology...
April 27, 2018: Science of the Total Environment
Li Liu, Ruiyi Wu, Yu Xia, Jiajun Wang, Ying Xiong, Yang Qu, Qilai Long, Li'an Sun, Jianming Guo
BACKGROUND: The aim of our study was to report our experience in the classification and therapeutic management strategies for spontaneous perirenal hemorrhage (SPH). METHODS: From September 2005 to April 2015, 20 patients with SPH were newly diagnosed in our hospital. Their clinical features, image findings, identification of underlying causes, and therapeutic management were retrospectively analyzed, and relevant literature was reviewed. In this study, patients were classified according to the degree of severity of the disease or emergency imaging diagnosis of underlying causes...
June 2018: International Journal of Surgery
Susan H Ebbels, Elspeth McCartney, Vicky Slonims, Julie E Dockrell, Courtenay Frazier Norbury
BACKGROUND: Paediatric speech and language therapist (SLT) roles often involve planning individualized intervention for specific children, working collaboratively with families and education staff, providing advice, training and coaching and raising awareness. A tiered approach to service delivery is currently recommended whereby services become increasingly specialized and individualized for children with greater needs. AIMS: To stimulate discussion regarding delivery of SLT services by examining evidence regarding the effectiveness of (1) intervention for children with language disorders at different tiers and (2) SLT roles within these tiers; and to propose an evidence-based model of SLT service delivery and a flowchart to aid clinical decision-making...
April 25, 2018: International Journal of Language & Communication Disorders
J Intra, C Sarto, N Tiberti, S Besana, C Savarino, P Brambilla
Matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS) is becoming a popular technology in clinical microbiology. It is a fast and highly specific method for the routine identification of micro-organisms. In this study, we evaluated the suitability of dermatophyte identification after only 2 days of colony growth using MALDI-TOF MS. Two protein extraction protocols were also evaluated consisting of either formic acid alone or of ethanol-formic acid-acetonitrile to achieve a complete protein extraction...
April 21, 2018: Letters in Applied Microbiology
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