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Wisconsin card sorting test

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https://www.readbyqxmd.com/read/28089694/affective-and-cognitive-correlates-of-ptsd-electrocortical-processing-of-threat-and-perseverative-errors-on-the-wcst-in-combat-related-ptsd
#1
Julia A DiGangi, Autumn Kujawa, Darrin M Aase, Joseph M Babione, Christopher Schroth, David M Levy, Amy E Kennedy, Justin E Greenstein, Eric Proescher, Robert Walters, Holly Passi, Scott A Langenecker, K Luan Phan
PTSD is characterized by both affective and cognitive dysfunction. Affectively, PTSD is associated with both heightened emotional reactivity and disengagement. Cognitively, perseverative thinking is a core feature of the disorder. In order to assess the interactive effects of affective and cognitive correlates of PTSD symptoms, 47 OEF/OIF/OND veterans completed an emotional faces matching task while EEG (i.e., late positive potential; LPP) was recorded, and separately completed the Wisconsin Card Sorting Test (WCST) to assess perseverative errors...
January 12, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28077120/altered-fractional-amplitude-of-low-frequency-fluctuation-associated-with-cognitive-dysfunction-in-first-episode-drug-na%C3%A3-ve-major-depressive-disorder-patients
#2
Manli Huang, Shaojia Lu, Liang Yu, Lingjiang Li, Peng Zhang, Jianbo Hu, Weihua Zhou, Shaohua Hu, Ning Wei, Jinwen Huang, Jian Weng, Yi Xu
BACKGROUND: Previous studies have demonstrated that abnormities of both resting-state brain activity and cognitive dysfunction are frequently observed in patients with major depressive disorder (MDD). However, the underlying relationship between these two aspects is less investigated. In this context, the aim of the present study was to investigate the association between cognitive dysfunction and altered resting-state brain function in first-episode drug-naïve MDD patients. METHODS: Twenty-five drug-naïve MDD patients and twenty-six age-, sex-, and education-matched normal controls were recruited in this study...
January 11, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28065522/perfluoroalkyl-substances-thyroid-hormones-and-neuropsychological-status-in-older-adults
#3
Srishti Shrestha, Michael S Bloom, Recai Yucel, Richard F Seegal, Robert Rej, Robert J McCaffrey, Qian Wu, Kurunthachalam Kannan, Edward F Fitzgerald
Minimal data exist regarding the neurotoxicity of perfluoroalkyl substances (PFASs) in aging populations and the possible mediating effects of thyroid hormones (THs). Hence, the aims of this study were to: (i) assess associations between PFASs and neuropsychological function, and (ii) determine if such associations are mediated by changes in circulating THs in an aging population. We measured perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), total thyroxine (T4) and free thyroxine (fT4) in serum and performed neuropsychological tests in 157 men and women aged 55-74 years and living in upper Hudson River communities...
December 30, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28049367/sensitivity-of-the-wisconsin-card-sorting-test-64-card-version-versus-the-tower-of-london-drexel-version-for-detecting-executive-dysfunction-in-children-with-epilepsy
#4
William S MacAllister, Moshe Maiman, Megan Marsh, Lindsay Whitman, Marsha Vasserman, Robyn J Cohen, Christine M Salinas
Executive function deficits are common in children and adolescents with epilepsy. Though the Wisconsin Card Sorting Task (WCST) is often considered the "gold standard" for executive function assessment, its sensitivity-particularly in the case of the 64-card version (WCST-64)-is insufficiently established in pediatric samples, including children and adolescents with epilepsy. The present investigation assesses the sensitivity of the WCST-64 in children and adolescents with epilepsy in comparison to another measure: the Tower of London - Drexel Version (TOL-DX)...
January 3, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28038438/executive-function-and-genetic-loading-in-nonpsychotic-relatives-of-schizophrenia-patients
#5
Erkan Aydın, Mine Cansu Ülgen, Abdülkadir Tabo, Özlem Devrim Balaban, Sema Yeşilyurt, Hüseyin Yumrukçal
Executive functions meet the "endophenotype candidate" criteria in neuropsychological measures for schizophrenic patients. To determine which area of executive functioning has the greatest value in differentiating the so called "candidate endophenotype" of schizophrenia through comparing the effect sizes of four commonly used executive function tests. A Wisconsin Card Sorting Test, a Stroop Test, a Trail Making Test and a Verbal Fluency Test were used to evaluate executive function in two study groups: healthy relatives of schizophrenia patients from simplex and multiplex families and a healthy control group...
December 21, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28009785/active-workstations-do-not-impair-executive-function-in-young-and-middle-age-adults
#6
Peter J Ehmann, Christopher J Brush, Ryan L Olson, Shivang N Bhatt, Andrea H Banu, Brandon L Alderman
PURPOSE: To examine the effects of self-selected low-intensity walking on an active workstation on executive functions in young and middle-aged adults. METHODS: Using a within-subjects design, 32 young (20.6 ± 2.0 yr) and 26 middle-aged (45.6 ± 11.8 yr) adults performed low-intensity treadmill walking and seated control conditions in randomized order on separate days, while completing an executive function test battery. Executive functions (EFs) were assessed using modified versions of the Stroop (inhibition), Sternberg (working memory), Wisconsin Card Sorting (cognitive flexibility), and Tower of London (global EF) cognitive tasks...
December 22, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28007464/proneness-to-aggression-and-its-inhibition-in-schizophrenia-interconnections-between-personality-traits-cognitive-function-and-emotional-processing
#7
Menahem I Krakowski, Pal Czobor
OBJECTIVE: Research on aggression in schizophrenia has focused on narrowly defined deficits, while ignoring interconnections among these impairments which provide better explanatory power. Our goal was to investigate interrelations among impairments in important domains related to aggression: personality traits, including psychopathy and impulsivity, cognition and processing of emotions. METHOD: 34 healthy controls, 37 high aggression (HAG) and 31 low aggression (LAG) patients with schizophrenia participated...
December 19, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/28005043/-the-changes-in-cognitive-impairment-in-patients-with-epilepsy-during-the-disease-course-on-example-of-executive-functions
#8
A A Zemlyanaya, V V Kalinin, E V Zheleznova, L V Sokolova
AIM: To identify the relationship between executive functions (EF), personality traits and clinical characteristics of disease course. MATERIAL AND METHODS: One hundred and five patients with partial epilepsy, including temporal lobe epilepsy (61%), lobe epilepsy (33%) and other forms (6%), were examined. Mean age of the patients was 30.24±8,67 years. EF were studied using the the Wisconsin Card Sorting Test (WCST) in 25 out of 105 patients of the main group. The patients were followed-up after 5...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28004481/multidimensional-cognitive-impairment-in-unipolar-and-bipolar-depression-and-the-moderator-effect-of-adverse-childhood-experiences
#9
Sara Poletti, Veronica Aggio, Silvia Brioschi, Sara Dallaspezia, Cristina Colombo, Francesco Benedetti
AIM: Studies have demonstrated neuropsychological deficits across a variety of cognitive domains in depression. These deficits are observable both in major depression (MDD) and in bipolar disorder (BD) and are present in each phase of the disorders, including euthymia. Adverse childhood experiences (ACE) have been associated to an increased risk to develop psychiatric disorders and cognitive deficits. The aim of the study was to assess neuropsychological performances in a sample of MDD and BD patients during a depressive episode compared to healthy controls and secondly to investigate if ACE affect the cognitive profile in the three groups...
December 22, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28003570/correlations-between-cognitive-impairments-and-employment-status-in-patients-with-diffuse-axonal-injury
#10
Shin Hirota, Motoki Inaji, Tadashi Nariai, Mutsuya Hara, Masashi Tamaki, Taketoshi Maehara, Hiroki Tomita, Osamu Tone
Patients with diffuse axonal injury (DAI) may initially present with prominent physical impairments, but their cognitive dysfunctions are more persistent and are attributable to later unemployment. In this study, we analyzed how the findings of early and delayed neuropsychological assessments correlated with employment outcome of patients with DAI. A total of 56 patients with DAI without motor or visual dysfunction were included in this study. The neuropsychological battery consisted of the Wechsler Adult Intelligent Scale - Revised (WAIS-R), Wechsler Memory Scale - Revised (WMS-R), Trail Making Test (TMT), Wisconsin Card Sorting Test (WCST), and Word Fluency Test (WFT)...
December 22, 2016: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/27978821/metabolic-syndrome-and-adverse-clinical-outcomes-in-patients-with-bipolar-disorder
#11
Ya-Mei Bai, Cheng-Ta Li, Shih-Jen Tsai, Pei-Chi Tu, Mu-Hong Chen, Tung-Ping Su
BACKGROUND: Metabolic syndrome (MetS) is highly prevalent among patients with bipolar disorder. MetS may cause complications in the brain, but studies investigating MetS-associated clinical psychiatric outcomes remain scant. METHODS: We enrolled clinically stable outpatients with bipolar disorder aged 18-65 years and performed anthropometric and fasting biochemical assessments to investigate MetS prevalence. We then performed clinical assessments by using the Young Mania Rating Scale for manic symptoms, the Montgomery-Åsberg Depression Rating Scale for depressive symptoms, the Positive and Negative Symptom Scale for psychotic symptoms, the Involuntary Movement Scale for tardive dyskinesia, the Barnes Akathisia Rating Scale for akathisia, the Udvalg for Kliniske Undersogelser for general side effects, the Schedule for Assessment of Insight for insight, the Global Assessment of Functioning scale for global functioning, and the Wisconsin Card Sorting Test (WCST) for cognitive executive function...
December 15, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27973723/influence-of-cognitive-function-on-quality-of-life-in-anorexia-nervosa-patients
#12
Sayo Hamatani, Masahito Tomotake, Tomoya Takeda, Naomi Kameoka, Masashi Kawabata, Hiroko Kubo, Yukio Tada, Yukiko Tomioka, Shinya Watanabe, Masatoshi Inoshita, Makoto Kinoshita, Masashi Ohta, Tetsuro Ohmori
AIMS: The purpose of this study was to elucidate determinants of quality of life (QOL) in anorexia nervosa (AN) patients. METHODS: Twenty-one female patients with AN participated in the study. QOL was assessed with the 36-Item Short Form Health Survey (SF-36), and cognitive function was evaluated using the Wisconsin Card Sorting Test Keio version (KWCST), the Rey Complex Figure Test (RCFT) and the Social Cognition Screening Questionnaire. Clinical symptoms were evaluated with the Beck Depression Inventory-II (BDI- II), the State-Trait Anxiety Inventory-Form JYZ (STAI-JYZ) and the Maudsley Obsessive Compulsive Inventory...
December 14, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27936927/evaluating-semantic-metamemory-retrospective-confidence-judgements-on-the-information-subtest
#13
Ricki L Ladowsky-Brooks
The current research explored the potential value of adding a supplementary measure of metamemory to the Information subtest of the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III in Study 1) or Fourth Edition (WAIS-IV in Study 2) in order to assess its relationship to other neuropsychological measures and to brain injury. After completing the Information subtest, neuropsychological examinees were asked to make retrospective confidence judgements (RCJ) by rating their answer certainty in the original order of item administration...
December 12, 2016: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/27911221/the-effect-of-a-third-party-observer-and-trait-anxiety-on-neuropsychological-performance-the-attentional-control-theory-act-perspective
#14
Fatemeh Rezaei, Nasrin Alsadat Hosseini Ramaghani, Rachel L Fazio
OBJECTIVE: Studies have reported that the presence of a third party observer (TPO) during neuropsychological assessments negatively affects the test performance of the examinee. The present study aimed to investigate the effects of a TPO and trait anxiety on neuropsychological performance according to Attentional Control Theory (ACT). METHOD: A sample of college students was recruited (n = 318) and then 80 participants were selected to represent the high and low trait anxiety groups...
December 2, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27905499/the-correlation-between-plasma-brain-derived-neurotrophic-factor-and-cognitive-function-in-bipolar-disorder-is-modulated-by-the-bdnf-val66met-polymorphism
#15
Sheng-Yu Lee, Tzu-Yun Wang, Shiou-Lan Chen, Yun-Hsuan Chang, Po-See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I Hui Lee, Kao Chin Chen, Yen Kuang Yang, Yi-Hsin Yang, Ru-Band Lu, Cheng-Sheng Chen
We explored the effect of the Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) on correlation between changes in plasma BDNF levels with cognitive function and quality of life (QoL) after 12 weeks of treatment in bipolar disorder (BD). Symptom severity and plasma BDNF levels were assessed upon recruitment and during weeks 1, 2, 4, 8 and 12. QoL, the Wisconsin Card Sorting Test (WCST), and the Conners' Continuous Performance Test (CPT) were assessed at baseline and endpoint. The BDNF Val66Met polymorphism was genotyped...
December 1, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27897266/evaluation-of-association-of-common-variants-in-htr1a-and-htr5a-with-schizophrenia-and-executive-function
#16
Fanglin Guan, Huali Lin, Gang Chen, Lu Li, Teng Chen, Xinshe Liu, Jiuqiang Han, Tao Li
The 5-HT1A receptor (HTR1A) and the 5-HT5A receptor (HTR5A) are key 5-HT receptors with distinct inhibitory functions. Studies have been conducted to investigate the association of a few HTR1A polymorphisms with schizophrenia, producing conflicting results, and the relationship between HTR5A and schizophrenia has not yet been well investigated. We aimed to examine the association of HTR1A and HTR5A with schizophrenia and executive function. The study included a discovery stage with 1,115 patients and 2,289 controls and a replication stage with 2,128 patients and 3,865 controls...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27892806/wisconsin-card-sorting-test-embedded-validity-indicators-developed-for-adults-can-be-extended-to-children
#17
Jonathan D Lichtenstein, Laszlo A Erdodi, Jaspreet K Rai, Anya Mazur-Mosiewicz, Lloyd Flaro
Past studies have examined the ability of the Wisconsin Card Sorting Test (WCST) to discriminate valid from invalid performance in adults using both individual embedded validity indicators (EVIs) and multivariate approaches. This study is designed to investigate whether the two most stable of these indicators-failures to maintain set (FMS) and the logistical regression equation S-BLRE-can be extended to pediatric populations. The classification accuracy for FMS and S-BLRE was examined in a mixed clinical sample of 226 children aged 7 to 17 years (64...
November 28, 2016: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/27890303/cognitive-effects-of-creatine-monohydrate-adjunctive-therapy-in-patients-with-bipolar-depression-results-from-a-randomized-double-blind-placebo-controlled-trial
#18
REVIEW
Ricardo Alexandre Toniolo, Francy de Brito Ferreira Fernandes, Michelle Silva, Rodrigo da Silva Dias, Beny Lafer
BACKGROUND: Depressive episodes and cognitive impairment are major causes of morbidity and dysfunction in individuals suffering from bipolar disorder (BD). Novel treatment approaches that target clinical and cognitive aspects of bipolar depression are needed, and research on pathophysiology suggests that mitochondrial modulators such as the nutraceutical creatine monohydrate might have a therapeutic role for this condition. METHODS: Eighteen (N=18) patients with bipolar depression according to DSM-IV criteria who were enrollled in a 6-week, randomized, double-blind, placebo-controlled trial of creatine monohydrate 6g daily as adjunctive therapy were submitted to neuropsychological assessments (Wisconsin Card Sorting Test, Digit Span subtest of the Wechsler Adult Intelligence Scale-Third Edition, Stroop Color-Word Test, Rey-Osterrieth complex figure test, FAS Verbal Fluency Test) at baseline and week 6...
November 20, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27889392/transcranial-magnetic-stimulation-to-dorsolateral-prefrontal-cortex-affects-conflict-induced-behavioural-adaptation-in-a-wisconsin-card-sorting-test-analogue
#19
Erica A Boschin, Rogier B Mars, Mark J Buckley
A substantial body of literature has proposed a role for dorsolateral prefrontal cortex (dlPFC) in supporting behavioural adaptation during conflict tasks. The vast majority of the evidence in support of this interpretation comes from neuroimaging studies. However, in order to unequivocally ascribe such a role to dlPFC, it is important to determine whether or not it is essential for this mechanism, and this can only be achieved by lesioning the area or interfering with its activity. In this study, we investigated the effects of repeated Transcranial Magnetic Stimulation (rTMS) to dlPFC on performance on a conflict version of a Wisconsin Card Sorting Test analogue (used previously in circumscribed lesion studies in monkeys) in neurologically healthy human participants...
January 8, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/27872798/factors-affecting-executive-functions-in-obstructive-sleep-apnea-syndrome-and-volumetric-changes-in-the-prefrontal-cortex
#20
Zahide Yılmaz, Nuray Voyvoda, Eda İnan, Pınar Bekdik Şirinocak, Rabia Terzi
PURPOSE: Obstructive sleep apnea syndrome (OSAS) is associated with cognitive changes and executive functions are among the cognitive domains most affected. However, it is not completely understood which of the factor(s) among hypoxemia, repeated arousal, and sleepiness affect the executive functions. This study aims to evaluate the possible relationship between the executive functions and nocturnal parameters, Epworth Sleepiness Scale (ESS) scores, and prefrontal cortex (PFC) volumes...
2016: SpringerPlus
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