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Wisconsin card sorting test

O Laporta-Hoyos, J Ballester-Plané, P Póo, A Macaya, M Meléndez-Plumed, E Vázquez, I Delgado, L Zubiaurre-Elorza, V L Botellero, A Narberhaus, E Toro-Tamargo, D Segarra, R Pueyo
PURPOSE: Quality of life (QOL) is a key outcome for people with cerebral palsy (CP), and executive functioning is an important predictor of QOL in other health-related conditions. Little is known about this association in CP or about its neural substrate. We aim to analyze the influence of executive functioning (including cognitive flexibility) as well as that of other psychological, motor, communication and socioeconomic variables on QOL and to identify neuroanatomical areas related to QOL in adolescents and adults with CP...
October 20, 2016: Quality of Life Research
Serap Argun Baris, Dilek Tuncel, Cigdem Ozerdem, Huseyin Kutlu, Tugba Onyilmaz, Ilknur Basyigit, Hasim Boyaci, Fusun Yildiz
BACKGROUND: The aim of this study is to evaluate the presence of neurocognitive dysfunctions, depression and anxiety and the effect of positive airway pressure (PAP) therapy on these alterations in Obesity Hypoventilation Syndrome (OHS) patients. METHODS: Ten healthy normal and obese controls, 10 OHS and 10 OSAS patients were included in the study. Short form-36, Beck Depression Scale and State-Trade Anxiety Inventory (STAI 1-2) were performed. Wisconsin Card Sorting Test (WCST), Montreal Cognitive Assessment Scale (MOCA), Enhanced Cued Recall (ECR) and Mini Mental Test (MMT) were used for neurocognitive evaluation...
2016: Multidisciplinary Respiratory Medicine
Conxa Perpiñá, Mara Segura, Sergio Sánchez-Reales
OBJECTIVE: The aim of the present study was to compare decision-making and cognitive flexibility in patients with disordered eating and weight, ranging from anorexia nervosa to obesity, and a healthy group. METHOD: Participants were 113 patients (86 with eating disorders and 27 with obesity), and a group of 39 healthy subjects; all completed the Iowa gambling task, the Wisconsin Card Sorting Test and several clinical self-report measures. RESULTS: Eating disordered and obese patients showed impaired performance on the decision-making task, and the obese group showed the worst performance on the set-shifting task...
October 15, 2016: Eating and Weight Disorders: EWD
Yu-Shu Huang, Christian Guilleminault, Fang-Ming Hwang, Chuan Cheng, Cheng-Hui Lin, Hsueh-Yu Li, Li-Ang Lee
Pediatric obstructive sleep apnea (OSA) is associated with chronic systemic inflammation and with cognitive impairments. This study aimed to investigate the status of proinflammatory cytokines, particularly interleukin 17 (IL-17) and interleukin 23 (IL-23) and cognition in pediatric OSA.Controls and OSA children participated in the study. Exclusion criteria were adenotonsillectomy, heart, neurological and severe psychiatric diseases, craniofacial syndromes, and obesity. Polysomnogram was followed by serum testing for inflammatory markers and neurocognitive tests such as continuous performance task (CPT) and Wisconsin card sorting test, questionnaires, analyses of plasma high-sensitivity C-reactive protein (HS-CRP), tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), interleukin 6 (IL-6), IL-17, and IL-23...
October 2016: Medicine (Baltimore)
Merve Cikili Uytun, Emel Karakaya, Didem Behice Oztop, Serife Gengec, Kazım Gumus, Sevgi Ozmen, Selim Doğanay, Semra Icer, Esra Demirci, Saliha Demirel Ozsoy
It is known that patients with Attention Deficit and Hyperactivity disorder (ADHD) and Conduct disorder (CD) commonly shows greater symptom severity than those with ADHD alone and worse outcomes. This study researches whether Default mode network (DMN) is altered in adolescents with ADHD + CD, relative to ADHD alone and controls or not. Ten medication-naïve boys with ADHD + CD, ten medication-naïve boys with ADHD and 10-age-matched typically developing (TD) controls underwent functional magnetic resonance imaging (fMRI) scans in the resting state and neuropsychological tasks such as the Wisconsin Card Sorting Test (WCST), Stroop Test TBAG Form (STP), Auditory Verbal learning Test (AVLT), Visual Auditory Digit Span B (VADS B) were applied to all the subjects included...
October 13, 2016: Brain Imaging and Behavior
Manli Huang, Yi Huang, Liang Yu, Jianbo Hu, Jinkai Chen, Pingbo Jin, Weijuan Xu, Ning Wei, Shaohua Hu, Hongli Qi, Yi Xu
BACKGROUND: This study aimed to explore differences in links between negative symptoms and neurocognitive deficits in adolescent and adult patients with first-episode schizophrenia. Schizophrenia is a mental disorder often characterized by positive and negative symptoms, reduced emotional expression, excitatory status, and poor cognitive ability. The severity of negative symptoms in patients with schizophrenia was reported to be more related to poor quality of life, weak functional ability, and heavy burden from families than with the severity of positive symptoms...
October 6, 2016: BMC Psychiatry
Rick A Stephan, Omar M Alhassoon, Kenneth E Allen, Scott C Wollman, Matt Hall, William J Thomas, Julia M Gamboa, Chrissy Kimmel, Mark Stern, Celina Sari, Constance J Dalenberg, Scott F Sorg, Igor Grant
BACKGROUND: Promising models for cognitive rehabilitation in alcohol treatment rest on a more nuanced understanding of the associated impairments in the multifaceted domains of executive functioning (EF) and impulsivity. OBJECTIVES: This meta-analysis examined the effects of alcohol on the individual subcomponents of EF and impulsivity in recently detoxified participants, including 1) Inhibition & Self-Regulation, 2) Flexibility & Set Shifting, 3) Planning & Problem Solving, 4) Reasoning & Abstraction, and 5) Verbal Fluency...
August 12, 2016: American Journal of Drug and Alcohol Abuse
C Tessier, K Sweers, A Frajerman, H Bergaoui, F Ferreri, C Delva, N Lapidus, A Lamaziere, J P Roiser, M De Hert, P Nuss
Schizophrenia is a severe mental condition in which several lipid abnormalities-either structural or metabolic-have been described. We tested the hypothesis that an abnormality in membrane lipid composition may contribute to aberrant dopamine signaling, and thereby symptoms and cognitive impairment, in schizophrenia (SCZ) patients. Antipsychotic-medicated and clinically stable SCZ outpatients (n=74) were compared with matched healthy subjects (HC, n=40). A lipidomic analysis was performed in red blood cell (RBC) membranes examining the major phospholipid (PL) classes and their associated fatty acids (FAs)...
October 4, 2016: Translational Psychiatry
Florian Lange, Caroline Seer, Sebastian Loens, Florian Wegner, Christoph Schrader, Dirk Dressler, Reinhard Dengler, Bruno Kopp
Cognitive inflexibility is a hallmark of executive dysfunction in Parkinson's disease (PD). This deficit consistently manifests itself in a PD-related increase in the number of perseverative errors committed on the Wisconsin Card Sorting Test (WCST). However, the neural processes underlying perseverative WCST performance in PD are still largely unknown. The present study is the first to investigate the event-related potential (ERP) correlates of cognitive inflexibility on the WCST in PD patients. Thirty-two PD patients and 35 matched control participants completed a computerized version of the WCST while the electroencephalogram (EEG) was recorded...
September 27, 2016: Neuropsychologia
Siting Chen, Xuyang Zuo, Yuan Li, Tian Jiang, Nan Zhang, Fang Dai, Qiu Zhang
AIM: The aim of this research is to study the ghrelin level, executive function, and their possible association in patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: 370 people were recruited between March 2015 and March 2016 in this study. Among them, 212 subjects were patients with T2DM and 158 subjects were included as control group. Their blood sample was analyzed for the level of ghrelin and other clinical indexes. Cognitive function was measured by Montreal Cognitive Assessment (MoCA) and executive function was evaluated by Wisconsin Card Sorting Test (WCST)...
September 30, 2016: Journal of Diabetes Investigation
Negin Paast, Zohreh Khosravi, Amir Hossein Memari, Monir Shayestehfar, Mohammad Arbabi
BACKGROUND: Cognitive functioning in individuals with Obsessive Compulsive Disorder (OCD) and with Obsessive Compulsive Personality Disorder (OCPD) has not been adequately studied. AIM: Examine the cognitive flexibility and planning ability of individuals with OCD and OCPD. METHODS: Twenty patients with OCD and 25 patients with OCPD who had not taken medication in the previous two weeks were identified in an outpatient psychology clinic in Tehran, and 25 healthy control subjects were identified from the university staff and local community residents...
February 25, 2016: Shanghai Archives of Psychiatry
Luciana Cassimiro, Daniel Fuentes, Ricardo Nitrini, Mônica Sanches Yassuda
OBJECTIVE: This study investigated the pattern of decision-making (DM) on the Iowa Gambling Task (IGT) in a sample of Portuguese speaking healthy older women in Brazil with limited education: illiterate, 1-2 years, and 3-4 years of schooling. METHODS: Around 164 non-demented community-dwelling women participated in the study. Among them 60 were illiterate, 52 had 1-2 years of schooling and 52 had 3-4 years of schooling. Participants completed the instruments: Brief Cognitive Screening Battery (BCSB), Mini-Mental State Examination, Verbal Fluency Test (animal category), Clock Drawing Test, Geriatric Depression Scale, Geriatric Anxiety Inventory, Digit Span Forward and Backward, Raven's Coloured Progressive Matrices, Wisconsin Card Sorting Test, and IGT...
September 27, 2016: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
M M Hurtado, M Triviño, M Arnedo, G Roldán, P Tudela
This research explored the relationship between executive functions (working memory and reasoning subtests of the Wechsler Adult Intelligence Scale, Trail Making and Stroop tests, fluency and planning tasks, and Wisconsin Card Sorting Test) and emotional intelligence measured by the Mayer-Salovey-Caruso Emotional Intelligence Test in patients with schizophrenia or borderline personality disorder compared to a control group. As expected, both clinical groups performed worse than the control group in executive functions and emotional intelligence, although the impairment was greater in the borderline personality disorder group...
September 20, 2016: Psychiatry Research
Yu-Shu Huang, Feng-Yuan Liu, Chin-Yang Lin, Ing-Tsung Hsiao, Christian Guilleminault
The relationship between functional brain images and performances in narcoleptic patients and controls is a new field of investigation. We studied 71 young, type 1 narcoleptic patients and 20 sex- and age-matched control individuals using brain positron emission tomography (PET) images and neurocognitive testing. Clinical investigation was carried out using sleep-wake evaluation questionnaires; a sleep-wake study was conducted with actigraphy, polysomnography, multiple sleep latency test (MSLT), and blood tests (with human leukocyte antigen typing)...
January 19, 2016: Sleep Medicine
Chrysoula Zouraraki, Ioannis Tsaousis, Penny Karamaouna, Leda Karagiannopoulou, Panos Roussos, Panos Bitsios, Stella G Giakoumaki
BACKGROUND: Increased schizotypal traits are observed in a percentage of the general population and in the schizophrenia-spectrum and have been associated with impairments in working memory. In this study we examined the effects of four schizotypal dimensions [Negative (NegS), Paranoid (ParS), Cognitive-Perceptual (CPS), Disorganized (DiS)] on executive working memory (EWM), as mediated by set-shifting, planning and control inhibition. We also examined whether these associations are moderated by family-history of psychosis...
August 21, 2016: Comprehensive Psychiatry
Joukje M Oosterman, Sophie M Heringa, Roy P C Kessels, Geert Jan Biessels, Huiberdina L Koek, Joseph H R Maes, Esther van den Berg
INTRODUCTION: Rule induction tests such as the Wisconsin Card Sorting Test require executive control processes, but also the learning and memorization of simple stimulus-response rules. In this study, we examined the contribution of diminished learning and memorization of simple rules to complex rule induction test performance in patients with amnestic mild cognitive impairment (aMCI) or Alzheimer's dementia (AD). METHOD: Twenty-six aMCI patients, 39 AD patients, and 32 control participants were included...
September 12, 2016: Journal of Clinical and Experimental Neuropsychology
Mohamed Abo-El-Asrar, Nevine G Andrawes, Menan A Rabie, Dina Aly El-Gabry, Abdel-Gawad Khalifa, Mariam El-Sherif, Karim Abdel Aziz
: The objective of this study was to investigate performance on memory, intelligence, and executive functions in children and adolescents with type 1 diabetes mellitus (T1DM) and to investigate the role of glycemic control, hypoglycemic attacks and diabetic ketoacidosis. We compared 50 subjects with T1DM with 30 healthy controls (ages between 7 and 16 years) using Benton Visual Retention Test (BVRT), the Arabic version of the Wechsler Intelligence Scale for Children (WISC), and Wisconsin Card Sorting Test (WCST)...
September 8, 2016: Applied Neuropsychology. Child
Wei Zheng, Ying-Qiang Xiang, Gabor S Ungvari, F K Helen Chiu, Chee H Ng, Ying Wang, Yu-Tao Xiang
BACKGROUND: Acetylcholinesterase (AChE) inhibitors have been shown to be effective in treating cognitive impairment in animal models and in human subjects with major depressive disorder (MDD). Huperzine A (HupA), a Traditional Chinese Medicine derived from a genus of clubmosses known as Huperzineserrata, is a powerful AChE inhibitor that has been used as an adjunctive treatment for MDD, but no meta-analysis on HupA augmentation for MDD has yet been reported. AIM: Conduct a systematic review and meta-analysis of randomized controlled trials (RCTS) about HupA augmentation in the treatment of MDD to evaluate its efficacy and safety...
April 25, 2016: Shanghai Archives of Psychiatry
Meredith J McHugh, Hong Gu, Yihong Yang, Bryon Adinoff, Elliot A Stein
Cocaine addiction is characterized by notoriously high relapse rates following treatment. Recent efforts to address poor treatment outcomes have turned to potential neural markers of relapse risk. Accordingly, the present study examined resting state functional connectivity (rsFC) within and between three large-scale cortical networks: the default mode network (DMN), salience network (SN) and executive control network (ECN). All three have been implicated in relapse-related phenomena including craving, withdrawal and executive control deficits...
September 7, 2016: Addiction Biology
Renata Terra de Oliveira, Lilian Assunção Felippe, Lilian Teresa Bucken Gobbi, Fabio Augusto Barbieri, Gustavo Christofoletti
OBJECTIVE: We have made a 3-arm trial (group vs. individual exercise vs. no treatment) to test the effects of a 6-month exercise program upon the executive functions in participants with Parkinson disease. METHODS: Twenty-four subjects were randomly allocated in 3 groups and undertook individualized exercises (G1, n = 8), group exercises (G2, n = 8), or monitoring (G3, n = 8). Executive functions were evaluated by means of the Wisconsin card sorting test and the Raven colored matrices, both assessed at the beginning of the program and after 6 months...
August 31, 2016: American Journal of Physical Medicine & Rehabilitation
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