keyword
MENU ▼
Read by QxMD icon Read
search

Breast ,axillary dissection

keyword
https://www.readbyqxmd.com/read/28636294/-selective-therapeutic-de-escalation-in-early-stage-breast-cancer
#1
Aikaterini Liapi, Apostolos Sarivalasis, Wendy Jeanneret Sozzi, Loïc Lelièvre, Khalil Zaman
The survival of patients with breast cancer has improved considerably thanks to adjuvant radiotherapy and systemic treatments. Due to the potential adverse events associated with these treatments, a de-escalation effort was undertaken concerning surgery and more recently the adjuvant treatments. Conservative breast surgery and the avoidance of axillary dissection were possible for the majority of the patients without detrimental effect on survival. New radiotherapy techniques and the consideration of cancer biology allowed to better protect the peripheral organs and even to avoid treatment in certain low-risk patients...
May 17, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28629690/axillary-lymph-node-sonographic-features-and-breast-tumor-characteristics-as-predictors-of-malignancy-a-nomogram-to-predict-risk
#2
Patricia Akissue de Camargo Teixeira, Luciano F Chala, Carlos Shimizu, José R Filassi, Jonathan Y Maesaka, Nestor de Barros
The purpose of this study was to build a mathematical model to predict the probability of axillary lymph node metastasis based on the ultrasonographic features of axillary lymph nodes and the tumor characteristics. We included 74 patients (75 axillae) with invasive breast cancer who underwent axillary ultrasonography ipsilateral to the tumor and fine-needle aspiration of one selected lymph node. Lymph node pathology results from sentinel lymph node biopsy or surgical dissection were correlated with lymph node ultrasonographic data and with the cytologic findings of fine-needle aspiration...
June 16, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28625445/prospective-double-blind-randomized-placebo-controlled-clinical-trial-of-the-pectoral-nerves-pecs-block-type-ii
#3
Barbara Versyck, Geert-Jan van Geffen, Patrick Van Houwe
STUDY OBJECTIVE: The aim of this clinical trial was to test the hypothesis whether adding the pectoral nerves (Pecs) block type II to the anesthetic procedure reduces opioid consumption during and after breast surgery. DESIGN: A prospective randomized double blind placebo-controlled study. SETTING: A secondary hospital. PATIENTS: 140 breast cancer stage 1-3 patients undergoing mastectomy or tumorectomy with sentinel node or axillary node dissection...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28611541/effectiveness-of-pertuzumab-trastuzumab-and-docetaxel-combination-neoadjuvant-chemotherapy-for-her2-positive-inflammatory-breast-cancer-a-case-report
#4
Yuji Yamashita, Yuko Tanaka, Seishi Kono, Meiko Nishimura, Toru Mukohara, Yukiko Morinaga, Shigeo Hara, Shintaro Takao
BACKGROUND: Inflammatory breast cancer (IBC) is the most aggressive form of primary breast cancer. CASE REPORT: A 40-year-old woman was referred to our hospital for evaluation of an induration in the right breast, suspected to be breast cancer. The tumor was diagnosed as estrogen receptor-negative, progesterone receptor-negative, HER2-positive, T4dN3cM0 stage IIIc IBC with axillary lymph node metastasis. Rather than surgical intervention, we chose a systemic treatment approach with pertuzumab, trastuzumab, and docetaxel (PTD) combination therapy which was shown to be effective for HER2-positive IBC in the NeoSphere trial...
March 2017: Breast Care
https://www.readbyqxmd.com/read/28610896/breast-conserving-therapy-for-breast-cancer-cosmetic-results-and-options-for-delayed-reconstruction
#5
Vera L Negenborn, José H Volders, Nicole M A Krekel, Max H Haloua, Mark-Bram Bouman, Marlon E Buncamper, Frank B Niessen, Hay A H Winters, Caroline B Terwee, Sybren Meijer, M Petrousjka van den Tol
OBJECTIVES: Optimisation of the cosmetic outcome after breast-conserving therapy (BCT) is important. We aimed to determine the cosmetic outcome following BCT and factors influencing this cosmesis and identify the most favourable options for delayed breast reconstruction. MATERIALS AND METHODS: Four reconstructive surgeons evaluated the cosmetic outcome of 109 patients after BCT. Additionally, the surgeons indicated which patients were amenable for delayed reconstruction and the preferred type of reconstruction...
May 18, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28608612/factors-impacting-the-accuracy-of-intra-operative-evaluation-of-sentinel-lymph-nodes-in-breast-cancer
#6
Catherine L Akay, Constance Albarracin, Tiffany Torstenson, Roland Bassett, Elizabeth A Mittendorf, Min Yi, Henry M Kuerer, Gildy V Babiera, Isabelle Bedrosian, Kelly K Hunt, Rosa F Hwang
Sentinel lymph node dissection (SLND) is a standard axillary staging technique in breast cancer and intraoperative sentinel lymph node (SLN) assessment is important for decision-making regarding additional treatment and reconstruction. This study was undertaken to investigate clinicopathologic factors impacting the accuracy of intraoperative SLN evaluation. Records of patients with clinically node-negative, invasive breast cancer who underwent SLND with frozen section intraoperative pathologic evaluation from 2004 to 2007 were reviewed...
June 13, 2017: Breast Journal
https://www.readbyqxmd.com/read/28602055/evaluation-of-the-benefit-of-radiotherapy-in-patients-with-occult-breast-cancer-a-population-based-analysis-of-the-seer-database
#7
Byoung Hyuck Kim, Jeanny Kwon, Kyubo Kim
Purpose: Few studies for occult breast cancer (OBC) have evaluated the effect of radiotherapy (RT) after mastectomy or axillary lymph node dissection (ALND) with/without breast surgery. Therefore, we investigated clinicopathologic factors of OBC with the impact of postoperative RT to determine its prognostic significance using large population-based data. Materials and Methods: We performed a retrospective cohort study using the Surveillance, Epidemiology, and End...
June 1, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28601382/long-term-follow-up-of-node-negative-breast-cancer-patients-evaluated-via-sentinel-node-biopsy-after-neoadjuvant-chemotherapy
#8
Hiroko Nogi, Ken Uchida, Rei Mimoto, Makiko Kamio, Hisashi Shioya, Yasuo Toriumi, Masafumii Suzuki, Eijiro Nagasaki, Tadashi Kobayashi, Hiroshi Takeyama
BACKGROUND: Sentinel node biopsy (SNB) is used to accurately assess axillary lymph node status in patients with node-negative breast cancer. However, its use after neoadjuvant chemotherapy (NAC) is controversial. We retrospectively assessed the usefulness of SNB after NAC by comparing axillary recurrence rates and other parameters in patients with clinically node-negative breast cancer who underwent SNB after NAC or without NAC. PATIENTS AND METHODS: At our hospital, 1179 patients with clinically node-negative breast cancer underwent SNB from April 2007 to December 2013...
May 8, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28594922/the-learning-curve-of-endoscopic-total-mastectomy-in-taiwan-a-multi-center-study
#9
Chin-Sheng Hung, Sheng-Wei Chang, Li-Min Liao, Cheng-Chiao Huang, Shih-Hsin Tu, Shou-Tung Chen, Dar-Ren Chen, Shou-Jen Kuo, Hung-Wen Lai, Ting-Mao Chou, Yao-Lung Kuo
INTRODUCTION: Laparoscopic techniques are commonly used in abdominal and gynecologic surgery, while breast cancer surgery has remained largely unchanged. In Asia, especially in Japan, many surgeons have started to use endoscopic surgery for breast cancer. In Taiwan, endoscopy-assisted breast surgery started in 2010. The benefits of this surgical method include smaller incisions, an axillary anatomic approach, clear vision, no oncologic compromise, and good cosmetic outcomes. This is the first report to discuss the learning curve of endoscopy-assisted breast surgery, including the difficulties experienced...
2017: PloS One
https://www.readbyqxmd.com/read/28593885/prognostic-factors-on-the-positivity-for-metastases-of-the-axillary-lymph-nodes-from-primary-breast-cancer
#10
Borislav Kondov, Goran Kondov, Zoran Spirovski, Zvonko Milenkovikj, Risto Colanceski, Gordana Petrusevska, Meri Pesevska
AIM: The aim of the study was to identify the impact of T stage, the presence of estrogen, progesterone, HER2neu receptors and the values of the Ki67 on the positivity for metastases of the axillary lymph nodes, from primary breast cancer. MATERIAL AND METHODS: 290 surgically treated patients for breast cancer were included in the study. All cases have been analyzed by standard histological analysis including microscopic analysis on standard H&E staining. For determining the molecular receptors - HER2neu, ER, PR, p53 and Ki67, immunostaining by PT LINK immunoperoxidase has been done...
March 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28589065/management-of-the-positive-axilla-in-2017
#11
REVIEW
Tolga Ozmen, Alicia Huff Vinyard, Eli Avisar
The role of surgery in breast cancer treatment and axillary staging is changing. It is not very far from today, when axillary dissection was the standard treatment and staging procedure for all stages of breast cancer. Today, we are on the edge of omitting axillary dissection even in patients with the axillary disease. In this review, we walked through the changes in axillary management throughout the past hundred years.
May 3, 2017: Curēus
https://www.readbyqxmd.com/read/28585745/sentinel-node-biopsy-for-early-breast-cancer-in-queensland-australia-during-2008-2012
#12
Paramita Dasgupta, Philippa H Youl, Christopher Pyke, Joanne F Aitken, Peter D Baade
BACKGROUND: Sentinel node biopsy (SNB) is now the standard of care for women with early-stage breast cancer. Despite lower morbidity than axillary lymph node dissection, widespread variation in SNB rates by non-clinical factors persists. We explored the factors associated with SNB usage and changes in those associations over time for recently diagnosed women. METHODS: We report here on a linked population-based cancer registry and hospital inpatient admission data set for 5577 women aged at least 20 years diagnosed with a first primary invasive early-stage node-negative breast cancer from July 2008 to 2012 in Queensland, Australia, who underwent breast cancer-related surgery within 2 years of diagnosis...
June 6, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28584266/novel-rapid-immunohistochemistry-using-an-alternating-current-electric-field-for-intraoperative-diagnosis-of-sentinel-lymph-nodes-in-breast-cancer
#13
Kaori Terata, Hajime Saito, Hiroshi Nanjo, Yuko Hiroshima, Satoru Ito, Kasumi Narita, Yoichi Akagami, Ryuta Nakamura, Hayato Konno, Aki Ito, Satoru Motoyama, Yoshihiro Minamiya
Axillary lymph node status and pathological diagnosis of sentinel lymph nodes (SLNs) is a prognostic factor that influences management of postoperative therapy. Recent reports indicate that one-step nucleic acid amplification and hematoxylin and eosin (HE)-stained frozen sections are effective for intraoperative diagnosis of SLNs. In the present study, we report a rapid-immunohistochemical staining (R-IHC) method that enables intraoperative detection of SLN metastases within 16 min using an anti-cytokeratin antibody...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28580881/blocking-the-cycle-cyclin-dependent-kinase-4-6-inhibitors-in-metastatic-hormone-receptor-positive-breast-cancer
#14
Seth A Wander, Erica L Mayer, Harold J Burstein
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
June 3, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28577722/minimal-impact-of-postmastectomy-radiation-therapy-on-locoregional-recurrence-for-breast-cancer-patients-with-1-to-3-positive-lymph-nodes-in-the-modern-treatment-era
#15
Minoru Miyashita, Hiroshi Tada, Akihiko Suzuki, Gou Watanabe, Hisashi Hirakawa, Masakazu Amari, Yoichiro Kakugawa, Masaaki Kawai, Akihiko Furuta, Kaoru Sato, Ryuichi Yoshida, Akiko Ebata, Hironobu Sasano, Keiichi Jingu, Noriaki Ohuchi, Takanori Ishida
INTRODUCTION: Given modern treatment strategies, controversy remains regarding whether postmastectomy radiation therapy (PMRT) is necessary for breast cancer patients with 1-3 positive axillary lymph nodes (ALN). Our aim was to assess the significance of PMRT in the modern treatment era for these patients. MATERIAL AND METHODS: We have conducted the retrospective multicenter study and identified 658 patients with 1-3 positive ALN who were treated with mastectomy and ALN dissection between 1999 and 2012...
June 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28576464/prognostic-impact-of-macrometastasis-linear-size-in-sentinel-node-biopsy-for-breast-carcinoma
#16
M P Foschini, R Miglio, C Quinn, B Belgio, P Regitnig, S Bianchi, R Nannini, H Buerger, H Kaya, I Illyés, J Kulka, C A Wells, J De Gaetano, I Lipeniece-Karele, G Cserni
AIM: The aim of the present study was to evaluate the risk of axillary non-sentinel lymph-node metastases (ALN) in breast cancer patients presenting macrometastasis (Mac-m) in the sentinel lymph node (SN). MATERIALS AND METHODS: A retrospective series of 1464 breast cancers from patients who underwent ALN dissection following the diagnosis of Mac-m in the sentinel node (SN) was studied. In all the cases the MAC-m linear size was evaluated and correlated with presence or absence of non-SN ALN metastases...
May 17, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28576178/updates-in-postmastectomy-radiation
#17
REVIEW
Jean L Wright, Arti Parekh
Although the use of postmastectomy radiation therapy (PMRT) is widely accepted in certain clinical situations, areas of controversy persist for some clinical scenarios. In addition, with significant shifts in the management of breast cancer, including omission of axillary nodal dissection in select sentinel node-positive patients and increased use of neoadjuvant chemotherapy, new clinical challenges have arisen regarding the role of PMRT. This article reviews the data to support current recommendations for postmastectomy radiation and explores areas of controversy and the studies that guide clinicians in these scenarios...
July 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/28561684/optimizing-breast-cancer-adjuvant-radiation-and-integration-of-breast-and-reconstructive-surgery
#18
Henry M Kuerer, Peter G Cordeiro, Robert W Mutter
Postmastectomy radiotherapy (PMRT) reduces the risk of locoregional and distant recurrence and improves overall survival in women with lymph node-positive breast cancer. Because of stage migration and improvements in systemic therapy and other aspects of breast cancer care, the absolute benefit of PMRT and regional nodal irradiation may be small in some favorable subsets of patients with very low nodal burden, and newer consensus guidelines do not mandate PMRT in all node-positive cases. The use and need for PMRT may considerably complicate breast reconstruction after mastectomy and therefore mandates multidisciplinary input that takes into account patient choice given potential risk of acute and long-term toxicities, benefits, life expectancy, the biology of the tumor, plans for systemic therapy, and actual tumor burden...
2017: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/28559767/st-gallen-vienna-2017-a-brief-summary-of-the-consensus-discussion-about-escalation-and-de-escalation-of-primary-breast-cancer-treatment
#19
REVIEW
Michael Gnant, Nadia Harbeck, Christoph Thomssen
For the second time, the St. Gallen Consensus Conference on early breast cancer treatment standards took place in Vienna, Austria, where it will remain for the foreseeable future (next date: March 20-23, 2019). With the probably most prominent line-up of global breast cancer experts and more than 3,000 participants from over 100 countries, the 2017 St. Gallen/Vienna conference again was a huge success. A generation change took place with respect to the Conference Co-Chairpersons. Traditionally, the experts from all continents reviewed publications from the past 2 years, and discussed whether new diagnostic or therapeutic means were ready for routine everyday practice...
May 2017: Breast Care
https://www.readbyqxmd.com/read/28549453/survival-and-axillary-recurrence-following-sentinel-node-positive-breast-cancer-without-completion-axillary-lymph-node-dissection-the-randomized-controlled-senomac-trial
#20
Jana de Boniface, Jan Frisell, Yvette Andersson, Leif Bergkvist, Johan Ahlgren, Lisa Rydén, Roger Olofsson Bagge, Malin Sund, Hemming Johansson, Dan Lundstedt
BACKGROUND: The role of axillary lymph node dissection (ALND) has increasingly been called into question among patients with positive sentinel lymph nodes. Two recent trials have failed to show a survival difference in sentinel node-positive breast cancer patients who were randomized either to undergo completion ALND or not. Neither of the trials, however, included breast cancer patients undergoing mastectomy or those with tumors larger than 5 cm, and power was debatable to show a small survival difference...
May 26, 2017: BMC Cancer
keyword
keyword
42851
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"