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https://www.readbyqxmd.com/read/29103838/cognitive-and-behavioral-comorbidities-in-rolandic-epilepsy-and-their-relation-with-default-mode-network-s-functional-connectivity-and-organization
#1
Isabell Ofer, Julia Jacobs, Nathalie Jaiser, Burak Akin, Jürgen Hennig, Andreas Schulze-Bonhage, Pierre LeVan
OBJECTIVE: Rolandic epilepsy (RE) is characterized by typical interictal-electroencephalogram (EEG) patterns mainly localized in centrotemporal and parietooccipital areas. An aberrant intrinsic organization of the default mode network (DMN) due to repeated disturbances from spike-generating areas may be able to account for specific cognitive deficits and behavioral problems in RE. The aim of the present study was to investigate cognitive development (CD) and socioemotional development (SED) in patients with RE during active disease in relation to DMN connectivity and network topology...
November 2, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29041835/assessment-of-executive-function-in-adhd-adolescents-contribution-of-performance-tests-and-rating-scales
#2
Virginia Krieger, Juan Antonio Amador-Campos
This study aimed to analyze performance on measures of neuropsychological and behavioral executive functions (EF) in adolescents with attention deficit hyperactivity disorder (ADHD), and to evaluate the utility of performance-based tests for predicting scores on behavioral EF ratings. One hundred eighteen adolescents (75 ADHD and 43 controls) aged 12-16 years performed neuropsychological tests and completed a behavior rating scale of EF. The ADHD group presented significantly lower scores than controls on Full Scale IQ (FSIQ) and all indexes of the WISC-IV, except the verbal comprehension index (VCI)...
October 18, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/29017430/characterizing-neurocognitive-late-effects-in-childhood-leukemia-survivors-using-a-combination-of-neuropsychological-and-cognitive-neuroscience-measures
#3
Ellen Van Der Plas, Lauren Erdman, Brian J Nieman, Rosanna Weksberg, Darci T Butcher, Deborah L O'connor, Susanne Aufreiter, Johann Hitzler, Sharon L Guger, Russell J Schachar, Shinya Ito, Brenda J Spiegler
Knowledge about cognitive late effects in survivors of childhood acute lymphoblastic leukemia (ALL) is largely based on standardized neuropsychological measures and parent reports. To examine whether cognitive neuroscience paradigms provided additional insights into neurocognitive and behavioral late effects in ALL survivors, we assessed cognition and behavior using a selection of cognitive neuroscience tasks and standardized measures probing domains previously demonstrated to be affected by chemotherapy. 130 ALL survivors and 158 control subjects, between 8 and 18 years old at time of testing, completed the n-back (working memory) and stop-signal (response inhibition) tasks...
October 10, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28955142/executive-function-features-in-drug-naive-children-with-oppositional-defiant-disorder
#4
Manfei Xu, Wenqing Jiang, Yasong DU, Yan Li, Juan Fan
BACKGROUND: Oppositional defiant disorder (ODD) that is characterized by markedly defiant, disobedient, and disruptive behavior in younger children has been regarded as disruptive behavior disorder (DBD), together with conduct disorder (CD). However, in contrast to CD, ODD does not include severe aggressive or antisocial behavior. AIM: This study aimed to examine executive function (EF) features of children with oppositional defiant disorder (ODD). METHODS: Cross sectional design was used in this study...
August 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28953856/effects-of-iron-supplementation-of-low-birth-weight-infants-on-cognition-and-behavior-at-7-years-a-randomized-controlled-trial
#5
Staffan K Berglund, Anna Chmielewska, Josefine Lindberg, Björn Westrup, Bruno Hägglöf, Mikael Norman, Magnus Domellöf
BACKGROUND: Low birth weight infants (LBW) are at increased risk of iron deficiency which has been associated with impaired neurodevelopment. We hypothesized that iron supplementation of LBW infants improve cognitive scores and reduce behavioral problems until school age. METHODS: We randomized 285 marginally LBW (2000-2500 g) infants to receive 0, 1, or 2 mg/kg/day of iron supplements from six weeks to six months of age. At 7 years of age, 205 participants were assessed regarding cognition using Wechsler Intelligence Scale for Children (WISC-IV) and behavior using the parental questionnaires Child Behavior Checklist (CBCL) and Five to Fifteen (FTF)...
September 27, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28939939/cognitive-performance-change-of-pediatric-patients-after-conducting-frontal-transcortical-approach-to-treat-lateral-ventricular-tumor
#6
Wanchun Zhu, Jintao He, Xiang Li, Lei Wang, Zheng Lu, Chunde Li, Jian Gong
OBJECTIVE: Applying frontal transcortical approach to treat lateral ventricular tumor is one of the most common neurosurgical manipulations. The frontal transcortical approach generally passes through the middle frontal gyrus in which there is no major function involved in the traditional sense. However, current researches have suggested that the prefrontal cortex (PFC) plays a central role in the whole network of the brain cognitive frame. In addition, cognitive function is crucial in growing and developmental stages and essential for the educational achievement, especially for children...
December 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28933607/a-randomised-controlled-trial-of-a-web-based-multi-modal-therapy-program-to-improve-executive-functioning-in-children-and-adolescents-with-acquired-brain-injury
#7
Adina Piovesana, Stephanie Ross, Owen Lloyd, Koa Whittingham, Jenny Ziviani, Robert S Ware, Lynne McKinlay, Roslyn N Boyd
OBJECTIVE: To examine the efficacy of a multi-modal web-based therapy program, Move it to improve it (Mitii™) delivered at home to improve Executive Functioning (EF) in children with an acquired brain injury (ABI). DESIGN: Randomised Waitlist controlled trial. SETTING: Home environment. PARTICIPANTS: Sixty children with an ABI were matched in pairs by age and intelligence quotient then randomised to either 20-weeks of Mitii™ training or 20 weeks of Care As Usual (waitlist control; n=30; 17 males; mean age=11y, 11m (±2y, 6m); Full Scale IQ=76...
October 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28716743/low-level-exposure-to-manganese-from-drinking-water-and-cognition-in-school-age-children
#8
Maryse F Bouchard, Céline Surette, Pierre Cormier, Delphine Foucher
BACKGROUND: Manganese (Mn) is an element found in the environment and certain geographic areas have elevated concentrations in soil and water du to natural conditions or anthropic activities. A growing body of data suggests that exposure to manganese in drinking water could be neurotoxic. OBJECTIVE: Firstly, we aimed to examine the association between exposure to manganese from drinking water and cognition in children consuming well water. Secondly, we also aimed to examine the relation between cognition and manganese concentrations in children's hair, nail, and saliva...
July 15, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28707956/use-of-the-21-item-test-with-children-and-adolescents-5-to-16-years-of-age
#9
Joseph J Ryan, Jennifer L Blacksmith, David S Kreiner, Laura Glass Umfleet
The goals of the present study were to: (a) collect preliminary normative data on the 21-Item Test in children and adolescents and to determine if cutoffs for biased responding in adults can be generalized to a younger population; (b) determine if Caucasian and Hispanic children perform differently on the test; and (c) ascertain the relationships of age and verbal intelligence with effort test performance. The 21-Item Test was administered to 153 children attending either a public (n = 96) or private (n = 57) school...
July 14, 2017: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/28683424/prenatal-phenolic-compounds-exposure-and-neurobehavioral-development-at-2-and-7years-of-age
#10
Ching-Chun Lin, Chun-Ju Chien, Meng-Shan Tsai, Chia-Jung Hsieh, Wu-Shiun Hsieh, Pau-Chung Chen
BACKGROUND: Phenolic compounds such as bisphenol A (BPA), nonylphenol (NP), and octylphenol (OP) are known as endocrine-disrupting compounds and are commonly used. Their impacts on the neurodevelopment of children are inconclusive. The current study aims to investigate the association between umbilical cord blood levels of BPA, NP, OP and neurodevelopmental outcomes at 2 and 7years of age. METHODS: The study was based on the Taiwan Birth Panel Study, a prospective birth cohort...
December 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28649514/early-hematopoietic-stem-cell-transplantation-in-a-patient-with-severe-mucopolysaccharidosis-ii-a-7%C3%A2-years-follow-up
#11
Anneliese L Barth, Tatiana S P C de Magalhães, Ana Beatriz R Reis, Maria Lucia de Oliveira, Fernanda B Scalco, Nicolette C Cavalcanti, Daniel S E Silva, Danielle A Torres, Alessandra A P Costa, Carmem Bonfim, Roberto Giugliani, Juan C Llerena, Dafne D G Horovitz
Mucopolysaccharidosis type II (MPS II - Hunter syndrome) is an X-linked lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2 sulfatase (I2S), leading to the accumulation of the glycosaminoglycans, affecting multiple organs and systems. Enzyme replacement therapy does not cross the blood brain barrier, limiting results in neurological forms of the disease. Another option of treatment for severe MPS, hematopoietic stem cell transplantation (HSCT) has become the treatment of choice for the severe form of MPS type I, since it can preserve neurocognition when performed early in the course of the disease...
September 2017: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/28603492/magnetoencephalographic-imaging-of-auditory-and-somatosensory-cortical-responses-in-children-with-autism-and-sensory-processing-dysfunction
#12
Carly Demopoulos, Nina Yu, Jennifer Tripp, Nayara Mota, Anne N Brandes-Aitken, Shivani S Desai, Susanna S Hill, Ashley D Antovich, Julia Harris, Susanne Honma, Danielle Mizuiri, Srikantan S Nagarajan, Elysa J Marco
This study compared magnetoencephalographic (MEG) imaging-derived indices of auditory and somatosensory cortical processing in children aged 8-12 years with autism spectrum disorder (ASD; N = 18), those with sensory processing dysfunction (SPD; N = 13) who do not meet ASD criteria, and typically developing control (TDC; N = 19) participants. The magnitude of responses to both auditory and tactile stimulation was comparable across all three groups; however, the M200 latency response from the left auditory cortex was significantly delayed in the ASD group relative to both the TDC and SPD groups, whereas the somatosensory response of the ASD group was only delayed relative to TDC participants...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28591025/neurocognitive-development-in-hiv-positive-children-is-correlated-with-plasma-viral-loads-in-early-childhood
#13
Valentin Weber, Daniel Radeloff, Bianca Reimers, Emilia Salzmann-Manrique, Peter Bader, Dirk Schwabe, Christoph Königs
Because of neurocognitive impairments in perinatally human immunodeficiency virus (HIV)-infected children and adolescents, this study aimed to demonstrate the effect of plasma viral loads and early initiation of sufficient combined antiretroviral therapy (cART) on neurocognitive development.In total, 14 perinatally infected HIV-positive children (median age 8.24 years [range: 6.0-16.74]) receiving lopinavir/ritonavir (LPV/r)-based ART underwent neurocognitive testing using the Wechsler Intelligence Score for Children, 4th Edition (WISC-IV)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28582687/evaluating-relationships-among-clinical-working-memory-assessment-and-inattentive-and-hyperactive-impulsive-behaviors-in-a-community-sample-of-children
#14
Alison M Colbert, Jin Bo
OBJECTIVE: This study examined relationships between inattentive and hyperactive/impulsive behaviors and working memory (WM) functioning, and the utility of WM in categorical diagnosis of ADHD versus considering ADHD symptoms on a continuum. METHOD: The study included 50 male children (6-12 years). Inattentive and hyperactive/impulsive behaviors were measured by the Conners-3P parent report, and WM was assessed by the WISC-IV WM subtests and Working Memory Index (WMI)...
June 2, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28564632/manganese-in-drinking-water-and-cognitive-abilities-and-behavior-at-10-years-of-age-a-prospective-cohort-study
#15
Syed Moshfiqur Rahman, Maria Kippler, Fahmida Tofail, Sven Bölte, Jena Derakhshani Hamadani, Marie Vahter
BACKGROUND: Cross-sectional studies have indicated impaired neurodevelopment with elevated drinking water manganese concentrations (W-Mn), but potential susceptible exposure windows are unknown. OBJECTIVES: We prospectively evaluated the effects of W-Mn, from fetal life to school age, on children's cognitive abilities and behavior. METHODS: We assessed cognitive abilities and behavior in 1,265 ten-year-old children in rural Bangladesh using the Wechsler Intelligence Scale for Children (WISC-IV) and the Strengths and Difficulties Questionnaire (SDQ), respectively...
May 26, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28553119/potential-role-of-pre-and-postnatal-testosterone-levels-in-attention-deficit-hyperactivity-disorder-is-there-a-sex-difference
#16
Liang-Jen Wang, Miao-Chun Chou, Wen-Jiun Chou, Min-Jing Lee, Sheng-Yu Lee, Pao-Yen Lin, Yi-Hsuan Lee, Yi-Hsin Yang, Cheng-Fang Yen
OBJECTIVE: Both prenatal testosterone (T) exposure and postnatal T levels have been associated with developing neural circuitry and behavioral systems. This study examined the potential correlation between pre- and postnatal T levels and behavioral and neurocognitive profiles of children with attention-deficit/hyperactivity disorder (ADHD). METHODS: Two hundred ADHD patients with a mean age of 8.7±2.0 years (158 boys and 42 girls) were recruited. The ratio of the length of the right index finger (2D) to that of the right ring finger (4D) (2D/4D ratio) served as a surrogate of prenatal T exposure, and postnatal T was determined using salivary T concentration...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28422947/factors-affecting-the-cognitive-profile-of-11-year-old-children-born-very-preterm
#17
Anna Nyman, Tapio Korhonen, Petriina Munck, Riitta Parkkola, Liisa Lehtonen, Leena Haataja
BackgroundPreterm birth is a risk for cognitive development. This study assessed the cognitive profile of children born very preterm at the age of 11 years as well as the associated risk factors.MethodsA total of 128 children born very preterm were included. Magnetic resonance imaging was performed at term age. Cognitive development was assessed using the full-scale intelligence quotient (IQ) and four domains of the Wechsler Intelligence Scale for Children, fourth edition (WISC-IV), Finnish translation. The results were compared with test norms...
August 2017: Pediatric Research
https://www.readbyqxmd.com/read/28374453/construct-validity-of-the-wechsler-intelligence-scale-for-children-fourth-uk-edition-with-a-referred-irish-sample-wechsler-and-cattell-horn-carroll-model-comparisons-with-15-subtests
#18
Gary L Canivez, Marley W Watkins, Rebecca Good, Kate James, Trevor James
BACKGROUND: Irish educational psychologists frequently use the Wechsler Intelligence Scale for Children - Fourth UK Edition (WISC-IV(UK) ; Wechsler, 2004, Wechsler Intelligence Scale for Children-Fourth UK Edition, London, UK, Harcourt Assessment) in clinical assessments of children with learning difficulties. Unfortunately, reliability and validity studies of the WISC-IV(UK) standardization sample have not yet been reported. Watkins et al. (2013, International Journal of School and Educational Psychology, 1, 102) found support for a bifactor structure with a large sample (N = 794) of Irish children who were administered the 10 WISC-IV(UK) core subtests in clinical assessments of learning difficulties and dominance of general intelligence...
April 3, 2017: British Journal of Educational Psychology
https://www.readbyqxmd.com/read/28348543/the-predictive-validity-of-four-intelligence-tests-for-school-grades-a-small-sample-longitudinal-study
#19
Jasmin T Gygi, Priska Hagmann-von Arx, Florine Schweizer, Alexander Grob
Intelligence is considered the strongest single predictor of scholastic achievement. However, little is known regarding the predictive validity of well-established intelligence tests for school grades. We analyzed the predictive validity of four widely used intelligence tests in German-speaking countries: The Intelligence and Development Scales (IDS), the Reynolds Intellectual Assessment Scales (RIAS), the Snijders-Oomen Nonverbal Intelligence Test (SON-R 6-40), and the Wechsler Intelligence Scale for Children (WISC-IV), which were individually administered to 103 children (Mage = 9...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28283836/the-faster-internal-clock-in-adhd-is-related-to-lower-processing-speed-wisc-iv-profile-analyses-and-time-estimation-tasks-facilitate-the-distinction-between-real-adhd-and-pseudo-adhd
#20
Marco Walg, Gerhard Hapfelmeier, Daniel El-Wahsch, Helmut Prior
Alterations in temporal processing may represent a primary cause of key symptoms in ADHD. This study is aimed at investigating the nature of time-processing alterations in ADHD and assessing the possible utility of testing time estimation for clinical diagnostics. Retrospective verbal time estimation in the range of several minutes was examined in 50 boys with ADHD and 53 boys with other mental disorders. All participants (age 7-16) attended an outpatient clinic for ADHD diagnostics. The diagnostic assessment included the WISC-IV...
October 2017: European Child & Adolescent Psychiatry
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