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https://www.readbyqxmd.com/read/28938049/detection-of-mutations-in-gyrb-using-denaturing-high-performance-liquid-chromatography-dhplc-among-salmonella-enterica-serovar-typhi-and-paratyphi-a
#1
Ruchi Gupta, Rajni Gaind, Laishram Chandreshwor Singh, Bianca Paglietti, Monorama Deb, Salvatore Rubino, John Wain, Seemi Farhat Basir
Background: Fluoroquinolone resistance is mediated by mutations in the quinolone-resistance determining region (QRDR) of the topoisomerase genes. Denaturing high performance liquid chromatography (DHPLC) was evaluated for detection of clinically important mutations in gyrB among Salmonella. Methods: Salmonella Typhi and S. Paratyphi A characterised for mutation in QRDR of gyrA, parC and parE were studied for mutation in gyrB by DHPLC and validated by sequencing...
December 1, 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28936625/the-reproducibility-of-4-km-time-trial-tt-performance-following-individualised-sodium-bicarbonate-supplementation-a-randomised-controlled-trial-in-trained-cyclists
#2
Lewis Anthony Gough, Sanjoy Kumar Deb, Andy Sparks, Lars Robert McNaughton
BACKGROUND: Individual time to peak blood bicarbonate (HCO3(-)) has demonstrated good to excellent reproducibility following ingestion of both 0.2 g kg(-1) body mass (BM) and 0.3 g kg(-1) BM sodium bicarbonate (NaHCO3), but the consistency of the time trial (TT) performance response using such an individualised NaHCO3 ingestion strategy remains unknown. This study therefore evaluated the reproducibility of 4-km TT performance following NaHCO3 ingestion individualised to time to peak blood bicarbonate...
September 21, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28934354/synthesis-of-irregular-graphene-oxide-tubes-using-green-chemistry-and-their-potential-use-as-reinforcement-materials-for-biomedical-applications
#3
Ángel Serrano-Aroca, Sanjukta Deb
Micrometer length tubes of graphene oxide (GO) with irregular form were synthesised following facile and green metal complexation reactions. These materials were obtained by crosslinking of GO with calcium, zinc or strontium chlorides at three different temperatures (24, 34 and 55°C) using distilled water as solvent for the compounds and following a remarkably simple and low-cost synthetic method, which employs no hazardous substances and is conducted without consumption of thermal or sonic energy. These irregular continuous GO networks showed a very particular interconnected structure by Field Emission Scanning Electron Microscopy with Energy-Disperse X-Ray Spectroscopy for elemental analysis and High-resolution Transmission Electron Microscopy with Scanning Transmission Electron Microscope Dark Field Imaging, and were analysed by Raman Spectroscopy...
2017: PloS One
https://www.readbyqxmd.com/read/28934265/comparative-effectiveness-of-different-transarterial-embolization-therapies-alone-or-in-combination-with-local-ablative-or-adjuvant-systemic-treatments-for-unresectable-hepatocellular-carcinoma-a-network-meta-analysis-of-randomized-controlled-trials
#4
Konstantinos Katsanos, Panagiotis Kitrou, Stavros Spiliopoulos, Ioannis Maroulis, Theodore Petsas, Dimitris Karnabatidis
BACKGROUND: The optimal transcatheter embolization strategy for patients with unresectable hepatocellular carcinoma (HCC) remains elusive. We conducted a systematic review and network meta-analysis (NMA) of different embolization options for unresectable HCC. METHODS: Medical databases were searched for randomized controlled trials evaluating bland transarterial embolization (TAE), conventional TACE, drug-eluting bead chemoembolization (DEB-TACE), or transarterial radioembolization (TARE), either alone or combined with adjuvant chemotherapy, or local liver ablation, or external radiotherapy for unresectable HCC up to June 2017...
2017: PloS One
https://www.readbyqxmd.com/read/28930706/giving-voice-to-the-voiceless-the-colorado-response-to-unrepresented-patients
#5
Deb Bennett-Woods, Jean Abbott, Jacqueline J Glover
Medical decision making on behalf of unrepresented patients is one of the most challenging ethical issues faced in clinical practice. The legal environment surrounding these patients is equally complex. This article describes the efforts of a small coalition of interested healthcare professionals to address the issue in Colorado. A brief history of the effort is presented, along with discussion of the legal, ethical, practical, and political dimensions that arose in Colorado's effort to address decision making for unrepresented patients through an extension of the existing Colorado Medical Treatment Decision Act (CRS 15-18)...
2017: Journal of Clinical Ethics
https://www.readbyqxmd.com/read/28929158/ru-os-dyads-based-on-a-mixed-bipyridine-terpyridine-bridging-ligand-modulation-of-the-rate-of-energy-transfer-and-ph-induced-luminescence-switching-in-the-infrared-domain
#6
Manoranjan Bar, Dinesh Maity, Sourav Deb, Shyamal Das, Sujoy Baitalik
A series of heterobimetallic complexes of compositions [(bpy/phen)2Ru(dipy-Hbzim-tpy)Os (tpy-PhCH3/H2pbbzim)](4+) (bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline, tpy-PhCH3 = 4'-(4-methylphenyl)-2,2':6',2''-terpyridine and H2pbbzim = 2,6-bis(benzimidazole-2-yl)pyridine)), derived from a heteroditopic bpy-tpy bridging ligand, were synthesized and thoroughly characterized in this work. The heterometallic complexes exhibit two successive one-electron reversible metal-centered oxidations corresponding to Os(II)/Os(III) at lower potential and Ru(II)/Ru(III) at higher potential...
September 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28923293/two-polysomnographic-features-of-rem-sleep-behavior-disorder-clinical-variations-insight-for-parkinson-s-disease
#7
Yun Shen, Yong-Ping Dai, Yi Wang, Jie Li, Kang-Ping Xiong, Cheng-Jie Mao, Jun-Ying Huang, Wei-Feng Luo, Chun-Feng Liu
INTRODUCTION: Loss of REM sleep muscle atonia (RWA) and dream-enactment behavior (DEB) are two associated features of REM sleep behavior disorder (RBD), which is frequently associated with Parkinson's disease (PD). Few studies have examined both DEB and RWA simultaneously in patients with PD. This study aimed to evaluate relationships between RWA, DEB and clinical characteristics of PD. METHODS: We conducted overnight polysomnography in 145 patients with PD. DEB (motor behaviors and/or vocalizations during REM) and increased RWA (IRWA; tonic and phasic chin EMG density ≥ 30% and ≥15%, respectively) were identified...
September 5, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28915126/toxicological-profile-of-organochlorines-aldrin-and-dieldrin-an-indian-perspective
#8
REVIEW
Noopur Sharma, Deepali Garg, Roumi Deb, Ratika Samtani
Several epidemiological studies have suggested various environmental factors as a possible cause for increased incidence of various abnormalities. Of the various environmental contaminants, the most prevalent and the most discussed are the endocrine disrupting chemicals. Contact of such disruptors with humans has become inevitable today. They are cosmopolitan and present from agriculture to industrial sectors, even in day-to-day consumer products. Aldrin and dieldrin belong to one such class of substances which are known to have a toxic effect on various physiological systems of the human body...
September 15, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28911082/borderline-resectable-pancreatic-cancer-an-evolving-concept
#9
N Petrucciani, T Debs, G Nigri, F D'Angelo, J Gugenheim, G Ramacciato
No abstract text is available yet for this article.
September 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28902313/variables-associated-with-disordered-eating-behaviors-among-freshman-students-from-mexico-city
#10
Concepción Díaz de León-Vázquez, José Alberto Rivera-Márquez, Ietza Bojorquez-Chapela, Claudia Unikel-Santoncini
Objective: To estimate the prevalence of disordered eating behaviors (DEB) and identify their associations with demographic and psychological variables among freshman students at a public university in Mexico City. Materials and methods: A sample of 892 subjects participated in the study. Bivariate and multinomial models were performed to determine associations between DEB and covariates. Results: Of those surveyed, 6.8% of the women and 4...
May 2017: Salud Pública de México
https://www.readbyqxmd.com/read/28893223/brca2-carriers-with-male-breast-cancer-show-elevated-tumour-methylation
#11
Siddhartha Deb, Kylie L Gorringe, Jia-Min B Pang, David J Byrne, Elena A Takano, kConFab Investigators, Alexander Dobrovic, Stephen B Fox
BACKGROUND: Male breast cancer (MBC) represents a poorly characterised group of tumours, the management of which is largely based on practices established for female breast cancer. However, recent studies demonstrate biological and molecular differences likely to impact on tumour behaviour and therefore patient outcome. The aim of this study was to investigate methylation of a panel of commonly methylated breast cancer genes in familial MBCs. METHODS: 60 tumours from 3 BRCA1 and 25 BRCA2 male mutation carriers and 32 males from BRCAX families were assessed for promoter methylation by methylation-sensitive high resolution melting in a panel of 10 genes (RASSF1A, TWIST1, APC, WIF1, MAL, RARβ, CDH1, RUNX3, FOXC1 and GSTP1)...
September 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28893003/spectrum-of-mri-appearance-of-mayer-rokitansky-kuster-hauser-mrkh-syndrome-in-primary-amenorrhea-patients
#12
Deb Kumar Boruah, Shantiranjan Sanyal, Bidyut Bikash Gogoi, Kangkana Mahanta, Arjun Prakash, Antony Augustine, Sashidhar Achar, Hiranya Baishya
INTRODUCTION: Mayer-Rokitansky-Kuster-Hauser (MRKH) synd-rome is a malformation in female genital tract due to interrupted embryonic development of para-mesonephric ducts leading to uterine and proximal vagina aplasia or hypoplasia. AIM: To analyse the MRI findings in females suspected of MRKH syndrome in a primary amenorrhea workup. MATERIALS AND METHODS: A cross-sectional study comprising of 11 patients of MRKH syndrome presented in a tertiary care centre from March 2016 to February 2017 evaluated in 1...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28890056/giant-chest-wall-arteriovenous-malformation-a-case-report-and-literature-review
#13
Cullen McCarthy, Subrato Deb, Suhair Maqusi, Joshua Gierman
INTRODUCTION: We present an interesting case of a 55 year-old male with a large left chest mass after significant cutaneous bleeding. CT angiogram of the chest revealed arteriovenous malformation with blood supply from subbranches of the left subclavian artery, left internal mammary artery and left external carotid artery. Measuring 5.0x14.0x10.8cm, the mass extended superior to the clavicle and inferior to the third rib with medial and lateral borders at the level of the clavicular head and coracoid, respectively...
September 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887915/hepatoprotective-naphthalene-diglucoside-from-neanotis-wightiana-aerial-parts
#14
Niranjan Das, Atanas G Atanasov, Prashanta Kumar Deb, Andrei Mocan, Seyed Mohammad Nabavi, Ranjib Ghosh, Biswanath Dinda
BACKGROUND: Neanotis wightiana (Wall. ex Wight & Arn) W.H. Lewis has been used in traditional medicine in India for the treatment of liver disorders. In fact, this plant is frequently used by the local people of Tripura for the treatment of liver disorder problems. In previous study on this plant we have isolated a hepatoprotective saponin, neanoside A. PURPOSE: Evaluation of in vivo hepatoprotective effects of isolated compounds from N. wightiana aerial parts on serum hepatic-biomarkers in CCl4- induced hepatotoxicity in rats to validate the traditional use of the plant...
September 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28880807/-my-heart-is-in-his-hands-the-lived-spiritual-experiences-of-congolese-refugee-women-survivors-of-sexual-violence
#15
Melissa A Smigelsky, Alison R Gill, Deb Foshager, Jamie D Aten, Hannah Im
The Democratic Republic of Congo (DRC) has experienced widespread violence, including sexual violence. Sexual violence toward women includes rape, genital mutilation, and sexual slavery. Many Congolese have sought to escape such conditions as refugees in the USA. In the present study, we examined lived spiritual experiences of nine Congolese refugee women survivors of sexual violence. Overall, this study provides new insights into participants' experiences of spirituality in the aftermath of sexual trauma and in living as a refugees...
October 2017: Journal of Prevention & Intervention in the Community
https://www.readbyqxmd.com/read/28878607/genetic-testing-in-a-cohort-of-complex-esophageal-atresia
#16
Eliane Beauregard-Lacroix, Jessica Tardif, Emmanuelle Lemyre, Zoha Kibar, Christophe Faure, Philippe M Campeau
The objective of the present study is to describe a cohort of complex esophageal atresia and the yield of genetic tests performed for such patients. We selected 45 patients with complex esophageal atresia (EA), namely those having at least one associated anomaly. We reviewed their medical records to assess clinical features, other diagnoses, and genetic investigations. Most of the patients had a diagnosis of VACTERL association (56%) with no genetic variant identified. Interestingly, 5 patients in the cohort (11%) had a right pulmonary hypoplasia or agenesis...
August 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/28878374/above-threshold-scattering-about-a-feshbach-resonance-for-ultracold-atoms-in-an-optical-collider
#17
Milena S J Horvath, Ryan Thomas, Eite Tiesinga, Amita B Deb, Niels Kjærgaard
Ultracold atomic gases have realized numerous paradigms of condensed matter physics, where control over interactions has crucially been afforded by tunable Feshbach resonances. So far, the characterization of these Feshbach resonances has almost exclusively relied on experiments in the threshold regime near zero energy. Here, we use a laser-based collider to probe a narrow magnetic Feshbach resonance of rubidium above threshold. By measuring the overall atomic loss from colliding clouds as a function of magnetic field, we track the energy-dependent resonance position...
September 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/28877140/prescription-opioid-use-and-the-risk-of-disability
#18
Gary M Franklin, Deb Fulton-Kehoe, Judith A Turner, Thomas Wickizer
No abstract text is available yet for this article.
September 1, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28874971/adjacent-disc-stress-following-floating-lumbar-spine-fusion-a-finite-element-study
#19
Gunti Ranga Srinivas, Malhar N Kumar, Anindya Deb
STUDY DESIGN: Experimental study. PURPOSE: The study aimed to develop a finite element (FE) model to determine the stress on the discs adjacent to the fused segment following different types of floating lumbar spinal fusions. OVERVIEW OF LITERATURE: The quantification of the adjacent disc stress following different types of floating lumbar fusions has not been reported. The magnitude of the stress on the discs above and below the floating fusion remains unknown...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28873822/the-hollybank-challenges-at-for-people-with-profound-disabilities
#20
Pam King, Kim Ludi, Deb Mortimer, Stephen Potter
The use of Assistive Technology with people with profound and multiple disabilities is a specialised subfield. Drawing on its authors' experiences and observations at a UK charitable foundation that offers specialised educational, residential and therapeutic facilities, this paper describes the distinct challenges that present themselves when applying AT to address the needs of this often-overlooked sector of the community. It is hoped that this will help raise awareness and contribute to improving the overall quality of AT provision in this area...
2017: Studies in Health Technology and Informatics
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