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https://www.readbyqxmd.com/read/28324705/more-pain-more-gain-blocking-the-opioid-system-boosts-adaptive-cognitive-control
#1
Henk van Steenbergen, Daniel H Weissman, Dan J Stein, Susan Malcolm-Smith, Jack van Honk
The ability to adaptively increase cognitive control in response to cognitive challenges is crucial for goal-directed behavior. Recent findings suggest that aversive arousal triggers adaptive increases of control, but the neurochemical mechanisms underlying these effects remain unclear. Given the known contributions of the opioid system to hedonic states, we investigated whether blocking this system increases adaptive control modulations. To do so, we conducted a double-blind, placebo-controlled psychopharmacological study (n=52 females) involving a Stroop-like task...
March 7, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28323838/bupropion-for-the-treatment-of-apathy-in-huntington-s-disease-a-multicenter-randomised-double-blind-placebo-controlled-prospective-crossover-trial
#2
Harald Gelderblom, Torsten Wüstenberg, Tim McLean, Lisanne Mütze, Wilhelm Fischer, Carsten Saft, Rainer Hoffmann, Sigurd Süssmuth, Peter Schlattmann, Erik van Duijn, Bernhard Landwehrmeyer, Josef Priller
OBJECTIVE: To evaluate the efficacy and safety of bupropion in the treatment of apathy in Huntington's disease (HD). METHODS: In this phase 2b multicentre, double-blind, placebo-controlled crossover trial, individuals with HD and clinical signs of apathy according to the Structured Clinical Interview for Apathy-Dementia (SCIA-D), but not depression (n = 40) were randomized to receive either bupropion 150/300mg or placebo daily for 10 weeks. The primary outcome parameter was a significant change of the Apathy Evaluation Scale (AES) score after ten weeks of treatment as judged by an informant (AES-I) living in close proximity with the study participant...
2017: PloS One
https://www.readbyqxmd.com/read/28323682/relationship-of-cognitive-function-to-motor-symptoms-and-mood-disorders-in-patients-with-isolated-dystonia
#3
Jennifer A Foley, R Saman Vinke, Patricia Limousin, Lisa Cipolotti
OBJECTIVE: To investigate the relationship of dystonia symptoms to cognitive function by comparing cognitive performance in patients with focal (cervical) and generalized dystonia subtypes and examining the differential contributions of severity of symptoms and mood disorders to cognition. BACKGROUND: Studies of the nonmotor syndrome in isolated dystonia have reported evidence of cognitive dysfunction, but the cause of this impairment remains unclear. Several studies have suggested that poor cognitive performance reflects the distracting effects of the motor symptoms and/or a mood disorder...
March 2017: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
https://www.readbyqxmd.com/read/28323517/differences-in-adolescent-emotion-regulation-and-impulsivity-a-group-comparison-study-of-school-based-recovery-students
#4
Beth S Russell, Anne Thompson Heller, Morica Hutchison
BACKGROUND: Recovery high schools (RHS) vary in organization and operating philosophy, but are designed to support the unique needs of students struggling with substance use disorders (SUD). Previous research on youth risk taking behaviors suggests emotion regulation is a key predictor of outcomes. Specifically, the ability to respond in adaptive rather than maladaptive ways is often associated with challenges of impulsivity, poor distress tolerance, and adolescent substance use. OBJECTIVES: The current study considers data from RHS students in order to answer research questions concerning impulsivity and emotion regulation of youth working to change their risk trajectories in comparison to group of typically developing youth...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28323332/shedding-light-on-gray-ing-areas-connectivity-and-task-switching-dynamics-in-aging
#5
Pauline L Baniqued, Kathy A Low, Mark A Fletcher, Gabriele Gratton, Monica Fabiani
Control-demanding tasks rely on communication among regions of the frontoparietal network, areas that undergo significant age-related decline. Here, we integrate data from brain anatomy, electrophysiology (ERPs), and optical imaging (event-related optical signals, EROS) to characterize the spatial and temporal dynamics of preparatory control processes in middle to old age. Older adults participated in an experiment that required switching between a position and a meaning task (spatial Stroop), a paradigm that has been shown to primarily recruit prefrontal cortex in opposite hemispheres and is thought to involve the corpus callosum (CC)...
March 21, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28323218/the-postural-control-can-be-optimized-by-the-first-movement-initiation-condition-encountered-when-submitted-to-muscle-fatigue
#6
Florian Monjo, Nicolas Forestier
We investigated whether and how the movement initiation condition (IC) encountered during the early movements performed following focal muscle fatigue affects the postural control of discrete ballistic movements. For this purpose, subjects performed shoulder flexions in a standing posture at maximal velocity under two movement IC, i.e., in self-paced conditions and submitted to a Stroop-like task in which participants had to trigger fast shoulder flexions at the presentation of incongruent colors. Shoulder flexion kinematics, surface muscle activity of focal and postural muscles as well as center-of-pressure kinematics were recorded...
March 18, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28323092/the-effect-of-deep-brain-stimulation-of-the-subthalamic-nucleus-on-executive-functions-impaired-verbal-fluency-and-intact-updating-planning-and-conflict-resolution-in-parkinson-s-disease
#7
Gyula Demeter, István Valálik, Péter Pajkossy, Agnes Szőllősi, Ágnes Lukács, Ferenc Kemény, Mihály Racsmány
Although the improvement of motor symptoms in Parkinson's disease (PD) after Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is well documented, there are open questions regarding its impact on cognitive functions. The aim of the present study was to assess the effect of bilateral DBS of the STN on executive functions in PD patients using a DBS wait-listed PD control group. Ten PD patients with DBS implantation (DBS group) and ten PD wait-listed patients (Clinical control group) participated in the study...
March 18, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28321202/emotionality-of-colors-an-implicit-link-between-red-and-dominance
#8
Stijn V Mentzel, Linda Schücker, Norbert Hagemann, Bernd Strauss
The color red has been shown to alter emotions, physiology, psychology, and behavior. Research has suggested that these alterations could possibly be due to a link between red and perceived dominance. In this study we examined if the color red is implicitly associated to the concept of dominance. In addition, we similarly hypothesized that blue is implicitly linked to rest. A modified Stroop word evaluation task was used in which 30 participants (23.07 ± 4.42 years) were asked to classify words shown in either red, blue, or gray (control condition), as being either dominant- or rest-related...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28318497/belief-bias-reasoning-in-non-clinical-delusion-prone-individuals
#9
T Anandakumar, E Connaughton, M Coltheart, R Langdon
BACKGROUND AND OBJECTIVES: It has been proposed that people with delusions have difficulty inhibiting beliefs (i.e., "doxastic inhibition") so as to reason about them as if they might not be true. We used a continuity approach to test this proposal in non-clinical adults scoring high and low in psychometrically assessed delusion-proneness. High delusion-prone individuals were expected to show greater difficulty than low delusion-prone individuals on "conflict" items of a "belief-bias" reasoning task (i...
March 15, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28315366/amygdala-functional-connectivity-is-associated-with-locus-of-control-in-the-context-of-cognitive-aging
#10
Ping Ren, Mia Anthony, Benjamin P Chapman, Kathi Heffner, Feng Lin
Locus of control (LOC) measures the extent to which individuals perceive control over their lives. Those with a more "internal" LOC feel self-sufficient and able to determine important aspects of their own future, while those with a more "external" LOC feel that their lives are governed by events beyond their control. Reduced internal LOC and increased external LOC have been found in cognitive disorders, but the neural substrates of these control perceptions are yet unknown. In the present study, we explored the relationship between amygdala functional connectivity and LOC in 18 amnestic mild cognitive impairment (MCI) and age-, sex-, and education-matched, 22 cognitively healthy controls (HC)...
March 14, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28298013/does-subjective-improvement-in-adults-with-intracranial-arachnoid-cysts-justify-surgical-treatment
#11
Katrin Rabiei, Per Hellström, Mats Högfeldt-Johansson, Magnus Tisell
OBJECTIVE Subjective improvement of patients who have undergone surgery for intracranial arachnoid cysts has justified surgical treatment. The current study aimed to evaluate the outcome of surgical treatment for arachnoid cysts using standardized interviews and assessments of neuropsychological function and balance. The relationship between arachnoid cyst location, postoperative improvement, and arachnoid cyst volume was also examined. METHODS The authors performed a prospective, population-based study. One hundred nine patients underwent neurological, neuropsychological, and physiotherapeutic examinations...
February 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28291524/more-than-just-channeling-the-role-of-subcortical-mechanisms-in-executive-functions-evidence-from-the-stroop-task
#12
William Saban, Shai Gabay, Eyal Kalanthroff
The literature has long emphasized the role of the cerebral cortex in executive functions. Recently, however, several researchers have suggested that subcortical areas might also be involved in executive functions. The current study explored the possibility that subcortical mechanisms have a functional role in adaptive resolution of Stroop interference. We asked 20 participants to complete a cued task-switching Stroop task with variable cue-target intervals (CTI). Using a stereoscope, we manipulated which eye was shown the relevant dimension and which was shown the irrelevant dimension...
March 10, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28288322/skill-related-physical-fitness-versus-aerobic-fitness-as-a-predictor-of-executive-functioning-in-children-with-intellectual-disabilities-or-borderline-intellectual-functioning
#13
Esther Hartman, Joanne Smith, Suzanne Houwen, Chris Visscher
Children with intellectual disabilities (ID) or borderline intellectual disabilities (BIF) often demonstrate impairments in executive functioning (EF). Studies in typically developing children show that aerobic fitness (AF) is positively related with EF. Skill-related physical fitness (SF) might, however, be a stronger predictor of EF than AF, as cognitive challenges are inherent in application of these skills. In this study, AF and SF were examined simultaneously in relationship with domains of EF in children with ID or BIF...
March 10, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28288178/can-application-and-transfer-of-strategy-be-observed-in-low-visibility-condition
#14
Imen El Karoui, Kalliopi Christoforidis, Lionel Naccache
It has been long assumed that cognitive control processes can only be applied on consciously visible stimuli, but empirical evidence is contradictory. In the present study, we investigated strategic adaptation to conflict both in unmasked and in low-visibility masked trials. Using a paradigm derived from the Stroop task, we studied the application of strategies, but also the transfer of a strategy developed in unmasked trials to masked trials, and the trial-to-trial dynamics of strategic processing. In unmasked trials, we found evidence of strategic adaptation to conflict, both in reaction times and in ERPs (N2 and P300)...
2017: PloS One
https://www.readbyqxmd.com/read/28285574/virtual-reality-exercise-on-a-home-based-phase-iii-cardiac-rehabilitation-program-effect-on-executive-function-quality-of-life-and-depression-anxiety-and-stress-a-randomized-controlled-trial
#15
Ágata Vieira, Cristina Melo, Jorge Machado, Joaquim Gabriel
PURPOSE: To analyse the effect of a six-month home-based phase III cardiac rehabilitation (CR) specific exercise program, performed in a virtual reality (Kinect) or conventional (booklet) environment, on executive function, quality of life and depression, anxiety and stress of subjects with coronary artery disease. METHODS: A randomized controlled trial was conducted with subjects, who had completed phase II, randomly assigned to intervention group 1 (IG1), whose program encompassed the use of Kinect (n = 11); or intervention group 2 (IG2), a paper booklet (n = 11); or a control group (CG), only subjected to the usual care (n = 11)...
March 13, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28285254/the-predictive-role-of-daily-cognitive-stimulation-on-executive-functions-in-bipolar-disorder
#16
Charles Cotrena, Laura Damiani Branco, André Ponsoni, Flávio Milman Shansis, Renata Kochhann, Rochele Paz Fonseca
This study aimed to estimate the predictive role of clinical and demographic variables on the three core executive functions (EF) - working memory (WM), inhibitory control (IC) and cognitive flexibility (CF) - in bipolar disorder (BD). The sample consisted of 38 patients with BD type I, 39 with BD type II, and 106 control participants with no mood disorders. Subjects completed the Hayling Test, Trail Making Test, Digit Span Backwards, Sentence Word Span Test, and Stroop Color-Word Test. Composite scores for WM, IC and CF were calculated, and their correlations with clinical and demographic variables were analyzed...
March 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28285156/the-role-of-cognition-for-different-stages-of-visuomotor-adaptation-in-younger-and-older-adults
#17
Anja Simon, Otmar Bock
A recent model identified three stages of learning, the first drawing on cognitive flexibility, the second on inhibition, and the third on automation. We explored the validity of this model for visuomotor learning and found that adaptation is associated with inhibition early during adaptation and with automaticity later on. An initial association with cognitive flexibility remained inconclusive. This work employs another marker of cognitive flexibility and extends our work to older adults. Twenty young and 20 older adults completed three cognitive tasks (switch task, Stroop task and four-choice-reaction-time-task)...
March 8, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28284828/self-control-predicts-attentional-bias-assessed-by-online-shopping-related-stroop-in-high-online-shopping-addiction-tendency-college-students
#18
Zhaocai Jiang, Xiuxin Zhao, Cancan Li
OBJECTIVE: The aim of this study was to examine the relationships of personality types (i.e., self-control, BAS/BIS) and online shopping addiction (OSA) behavior and to investigate whether high-OSA tendency individuals display attentional biases toward online shopping-related (OS-related) stimuli as well as the links between attentional bias and personality types. METHOD: The study included 98 college students divided into three groups (i.e., high-, medium- and low-OSA) according to their OSA behavior...
February 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28282326/effects-of-mental-fatigue-on-endurance-performance-in-the-heat
#19
Jeroen Van Cutsem, Kevin De Pauw, Luk Buyse, Samuele Marcora, Romain Meeusen, Bart Roelands
PURPOSE: Mental fatigue is a psychobiological state caused by prolonged periods of demanding cognitive activity and has been observed to decrease time-trial (TT) endurance performance by ~3,5% in normal ambient temperatures. Recently it has been suggested that heat may augment the negative effect of mental fatigue on cognitive performance, raising the question whether it may also amplify the effect of mental fatigue on TT-performance. METHODS: In 30 °C and 30% relative humidity, ten endurance-trained male athletes (Age: 22 ± 3 y; Wmax: 332 ± 41 W) completed two experimental conditions: intervention (I; 45-min Stroop task) and control (C; 45-min documentary)...
March 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28280596/increasing-cognitive-load-attenuates-right-arm-swing-in-healthy-human-walking
#20
Tim Killeen, Christopher S Easthope, Linard Filli, Lilla Lőrincz, Miriam Schrafl-Altermatt, Peter Brugger, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger
Human arm swing looks and feels highly automated, yet it is increasingly apparent that higher centres, including the cortex, are involved in many aspects of locomotor control. The addition of a cognitive task increases arm swing asymmetry during walking, but the characteristics and mechanism of this asymmetry are unclear. We hypothesized that this effect is lateralized and a Stroop word-colour naming task-primarily involving left hemisphere structures-would reduce right arm swing only. We recorded gait in 83 healthy subjects aged 18-80 walking normally on a treadmill and while performing a congruent and incongruent Stroop task...
January 2017: Royal Society Open Science
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