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https://www.readbyqxmd.com/read/28528585/why-patients-should-be-involved-in-health-technology-assessment
#1
Janet Wale, Anna Mae Scott, Bjørn Hofmann, Sarah Garner, Eric Low, Lloyd Sansom
OBJECTIVES: Some countries make considerable effort to involve patients and patient groups in their health technology assessment (HTA) processes; others are only just considering or are yet to consider patient involvement in HTA. METHODS: This commentary offers four arguments why patient involvement should be prioritized by those HTA agencies that do not yet involve patients: (1) from a patients' rights perspective, (2) based on patient and community values, (3) centering on evidentiary contributions, and (4) from a methodological perspective...
May 22, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28520990/one-step-further-in-sono-palpation-during-ultrasound-imaging-self-palpation
#2
Levent Özçakar, Ayse Merve Ata, Bayram Kaymak, Scott Evans, Murat Kara
No abstract text is available yet for this article.
May 17, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28518001/propranolol-effects-on-decompression-sickness-in-a-simulated-dissub-rescue-in-swine
#3
Angela S Forbes, David P Regis, Aaron A Hall, Richard T Mahon, William A Cronin
INTRODUCTION: Disabled submarine (DISSUB) survivors may face elevated CO2 levels and inert gas saturation, putting them at risk for CO2 toxicity and decompression sickness (DCS). Propranolol was shown to reduce CO2 production in an experimental DISSUB model in humans but its effects on DCS in a DISSUB rescue scenario are unknown. A 100% oxygen prebreathe (OPB) reduces DCS incidence and severity and is incorporated into some DISSUB rescue protocols. We used a swine model of DISSUB rescue to study the effect of propranolol on DCS incidence and mortality with and without an OPB...
April 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28516067/cognitomics-a-new-approach-for-the-evaluation-of-the-relationship-between-diseases-and-cognition-to-be-designed-based-on-normal-behavioral-tendencies-in-real-life-a-conceptual-framework
#4
EDITORIAL
Ata Pourabbasi, Bagher Larijani
The relationship between medical diseases and cognition has been a point of interest in the last decades. In recent years studies in this field have developed significantly applying various tools such as cognitive tests using psychometric assessments and brain imaging techniques. The main focus of cognitive function in this studies is the process through which this cognition is obtained. It seems a novel methodology is needed while assessing the impact of diseases such as diabetes on cognition based on heavenly religious teachings in which cognition is believed to be the main source of human bliss and not just some measurable quantitative components...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28515095/a-prognostic-index-for-chronic-and-smoldering-type-adult-t-cell-leukemia-lymphoma
#5
Hiroo Katsuya, Mototsugu Shimokawa, Kenji Ishitsuka, Kazuhiro Kawai, Masahiro Amano, Atae Utsunomiya, Ryosuke Hino, Shuichi Hanada, Tatsuro Jo, Kunihiro Tsukasaki, Yukiyoshi Moriuchi, Eisaburo Sueoka, Shinichiro Yoshida, Hitoshi Suzushima, Masaharu Miyahara, Kiyoshi Yamashita, Tetsuya Eto, Junji Suzumiya, Kazuo Tamura
Adult T-cell leukemia-lymphoma (ATL) has been divided into 4 clinical subtypes: acute, lymphoma, chronic, and smoldering. The aim of this study is to develop a novel prognostic index (PI) for chronic and smoldering ATL. We conducted a nationwide retrospective survey on ATL patients, and 248 fully eligible individuals were used in this analysis. In the univariate analysis, gender, performance status, log10[soluble interleukin-2 receptor (sIL-2R)], neutrophils count, and lymphadenopathy showed P values less than ...
May 17, 2017: Blood
https://www.readbyqxmd.com/read/28512707/geochemistry-and-sources-of-fluoride-and-nitrate-contamination-of-groundwater-in-lar-area-south-iran
#6
Mohsen Rezaei, Masume Nikbakht, Ata Shakeri
Groundwater quality in bone-dry and semiarid areas of Iran is decreasing because of contaminants from natural origins and anthropogenic sources. Among many harmful contaminants, nitrate and fluoride ions are more common. This study was carried out with the aim of determining geochemical processes controlling chemistry of groundwater with special reference to nitrate and fluoride enrichment in groundwater in Lar plain aquifer, south of Iran. Groundwater samples were collected from 17 sites and analyzed for main constituents (Na, K, Ca, Mg, Cl, SO4(2-), HCO3(-), F(-), and NO3(-))...
May 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28506409/the-surgical-approach-to-nodule-thyr-3-4-after-the-2-2014-nccn-and-2015-ata-guidelines
#7
Paolo Del Rio, Paola Pisani, Chiara Montana Montana, Simona Cataldo, Michela Marina, Graziano Ceresini
BACKGROUND: The incidence of palpables thyroid nodules in general population is 5% and the prevalence of non -palpable nodules is higher (35-60%) in the endemic goiter area. In the last years the new guidelines and new classification related to thyroid nodule have changed the indication to treat it. MATERIAL AND METHOD: We analyzed the patients treated from January 2013 to June 2016 for Thyr 3 and Thyr 4 thyroid nodule sec. Bethesda system. We have divided in I and II period related to the 2...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28503181/development-of-a-critical-nitrogen-dilution-curve-of-double-cropping-rice-in-south-china
#8
Zhiyuan He, Xiaolei Qiu, Syed Tahir Ata-Ul-Karim, Yanda Li, Xiaojun Liu, Qiang Cao, Yan Zhu, Weixing Cao, Liang Tang
The concept of critical nitrogen (Nc) concentration can be implemented to diagnose in-season plant nitrogen (N) status for optimizing N fertilizer management. The Nc dilution curves have been established for rice (Oryza sativa L.) grown in different climatic regions, yet no attempt has been made to develop the Nc dilution curve for double cropping rice regions. This study was undertaken to develop the Nc dilution curves for double cropping rice in south China for assessment of in-season N status and to establish the relationships N nutrition index (NNI) and relative yield (RY) for in-season prediction of rice grain yield...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28500127/the-efficacy-of-hyperbaric-oxygen-therapy-in-the-treatment-of-central-retinal-artery-occlusion
#9
Andreia Soares, Nuno L Gomes, Luís Mendonça, Carla Ferreira
Central retinal artery occlusion (CRAO) is an ophthalmological emergency. Various treatment modalities have been tried, but none have shown to alter natural history of the disease. Hyperoxia can restore retinal oxygenation, and favourable results were obtained with hyperbaric oxygen therapy (HBOT). We report two patients with sudden visual loss due to CRAO treated with HBOT. Case 1: a 61-year-old female, presented with CRAO in her left eye(OS). She was submitted to eight sessions of HBOT(2.4atmosphere absolute (ATA))...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28499093/the-segond-fracture-is-an-avulsion-of-the-anterolateral-complex
#10
Humza Shaikh, Elmar Herbst, Ata Amir Rahnemai-Azar, Marcio Bottene Villa Albers, Jan-Hendrik Naendrup, Volker Musahl, James J Irrgang, Freddie H Fu
BACKGROUND: The Segond fracture was classically described as an avulsion fracture of the anterolateral capsule of the knee. Recently, some authors have attributed its pathogenesis to the "anterolateral ligament" (ALL). Biomechanical studies that have attempted to reproduce this fracture in vitro have reported conflicting findings. PURPOSE: To determine the anatomic characteristics of the Segond fracture on plain radiographs and magnetic resonance imaging (MRI), to compare this location with the location of the ALL described in prior radiographic and anatomic publications, and to determine the fracture's attachments to the soft tissue anterolateral structures of the knee...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28498960/which-is-worse-comparison-of-art-outcome-between-women-with-primary-or-recurrent-endometriomas
#11
Baris Ata, Sezcan Mumusoglu, Kiper Aslan, Ayse Seyhan, Isil Kasapoglu, Berrin Avci, Bulent Urman, Gurkan Bozdag, Gurkan Uncu
STUDY QUESTİON: Are live birth rates (LBR) different after ART cycles between women with primary or recurrent endometrioma? SUMMARY ANSWER: Women with recurrent endometrioma have similar LBR as compared to patients with primary endometrioma. WHAT IS ALREADY KNOWN: Recurrence rate can be as high as 29% after endometrioma excision. Prior studies on management of endometrioma before ART involve primary endometriomas. There is limited information regarding the prognosis of women with recurrent endometriomas...
May 12, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28495625/nickel-nanoparticle-synthesis-using-camellia-sinensis-as-reducing-and-capping-agent-growth-mechanism-and-photo-catalytic-activity-evaluation
#12
Ismat Bibi, Shagufta Kamal, Adeel Ahmed, Munawar Iqbal, Shazia Nouren, Kashif Jilani, Nosheen Nazar, Muhammad Amir, Ansar Abbas, Sadia Ata, Farzana Majid
Recently, the biogenic synthesis of nanoparticle attracted the attention of scientific community due to its simplicity, ease and eco-friendly nature. In the present study, Camellia Sinensis (C. Sinensis) leaves extract was employed for the synthesis of nickel nanoparticles (NiNPs). The fabricated NiNPs were characterized by Scanning electron microscopy (SEM) and Energy-dispersive X-ray (EDX), magnetic properties and X-ray diffraction techniques. The photocatalytic activity (PCA) was evaluated by degrading crystal violet (CV) dye...
May 8, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28489213/effects-of-heparin-and-hyperbaric-oxygenation-on-necrosis-reduction-in-an-animal-model-for-degloving-injuries
#13
Douglas Neumar Menon, Letícia Teixeira, Natalha Bristot Paurosi, Marcio Eduardo Barros
Objective: to evaluate the efficacy of the treatment with hyperbaric oxygen therapy or with topical and intralesional heparin in an animal model of degloving lesions. Methods: we conducted an experimental study with adult, male Wistar rats submitted to degloving of the left hind limb and divided into four groups according to the treatment: Group 1 (control) - without treatment; Group 2 (Heparin) - intralesional application at the time of surgery and topically, in the postoperative period, with heparin spray 10,000IU/mL; Group 3 (hyperbaric oxygenation) - daily sessions of 30 minutes in a hyperbaric chamber with 100% oxygen and 2 ATA pressure; Group 4 (positive control) - administration of a single dose of 45 mg/kg of intraperitoneal allopurinol...
January 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28483257/protective-role-of-intratympanic-nigella-sativa-oil-against-gentamicin-induced-hearing-loss
#14
Deniz Tuna Edizer, Ozgur Yigit, Zehra Cinar, Mehmet Gul, Eyyup Kara, Birgul Yigitcan, Duygu Hayır, Ahmet Atas
OBJECTIVE: Aminoglycosides, used to combat with life-threatening infections, have a substantial risk of hearing loss. Nigella sativa is an annual herbaceous plant and used for treatment of many diseases for ages. We aimed to investigate the protective role of intratympanic nigella sativa oil against gentamicin induced hearing loss in an animal model. METHODS AND MATERIALS: Twenty eight guinea pigs were randomly divided into four groups: i-control, ii- Intratympanic nigella sativa oil (IT-NSO), iii- Intraperitoneal gentamicin (IP-G) and iv- Intraperitoneal gentamicin and intratympanic nigella sativa oil (IP-G + IT-NSO)...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28477409/alma-ata-to-berlin-diabetes-prevention-and-treatment-to-achieve-healthy-living
#15
S Kalra, T Lauritzen, T Sharmanov, Z Akanov, F Al Awadi, A K Das, C Espinosa López, G Medea, P Oh, Y Samoilova, M Shestakova, P Netto, X Cos, M Farghaly, X Du
The 1978 Declaration of Alma-Ata [1], issued at the International Conference on Primary Health Care*, held at Alma-Ata, Kazakhstan (former Soviet Union), is a landmark in public health. By stating that health is a fundamental human right, the declaration promoted interest and action in the field of public health, specifically primary health care. While it highlighted maternal child health and infectious disease control, it also clearly addressed chronic illness care, the availability of appropriate pharmaceuticals, and the need for preventive, curative and rehabilitative services...
May 6, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28476714/investigation-of-anti-proliferative-and-antioxidative-effects-of-some-bis-%C3%AE-amino-phosphinic-acid-derivatives
#16
Taner Dastan, Sevgi Durna Dastan, Mehmet Atas, Cahit Orek, Pelin Koparir, Akif Evren Parlak, Inanc Baral, Metin Koparir, Ahmet Cetin
Aminophosphinic acids which are organophosphorus compounds widely investigated for potential production of antibacterial, antitumor and antiviral materials. In vitro antioxidant, cytotoxic and antimicrobial activities of synthesized novel compounds of 8 different bis(β-amino alkyl)phosphinic acids (4a-h) were investigated on MCF-7 breast adenocarcinoma cell and human umbilical vein endothelial cell (HUVEC) cultures. Malondialdehyde (MDA) levels were evaluated as an indication of lipid peroxidation in cell cultures for antioxidant capacities...
September 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28474346/development-of-sechem-concept-for-isolation-and-chemical-modification-of-gossypol-directly-from-cienfuegosia-digitata
#17
Mohamed Vall Sidi Boune, Brahim Ould Elemine, Thomas Lepitre, Abderrahmane Ould Hadou, Ahmed Aliyenne, Ahmed Ismaïl Boumediana, Adam Daïch, Mohamed Othman, Ata Martin Lawson
INTRODUCTION: Gossypol is an axially chiral natural polyphenol classically extracted from the Malavaceae family. Nevertheless, its extraction and isolation from a plant can be quite complicated and extremely time-consuming since gossypol is known to be sensitive to degradation under solvents, high temperature and light action. Moreover, its purification over column chromatography is a challenging problem due to its ability to oxidise and the existence of various tautomer forms. OBJECTIVE: To develop an efficient "one-step" strategy for simultaneous extraction and semi-synthesis by short-circuiting critical gossypol isolation and purification steps...
May 5, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28470825/three-in-one-go-thermo-solvent-and-catalytic-stability-by-engineering-the-cofactor-binding-element-of-amine-transaminases
#18
Tim Börner, Sebastian Rämisch, Sebastian Bartsch, Andreas Vogel, Patrick Adlercreutz, Carl Grey
Amine transaminases (ATA) catalyse enantioselectively the direct amination of ketones, but the insufficient stability during catalysis limits their industrial applicability. Recently, we revealed that ATAs suffer from a substrate-induced inactivation mechanism involving dissociation of the enzyme-cofactor intermediate. Here, we report on engineering the cofactor-ring binding element that also shapes the active site entrance. Only two point mutations in this motif improved thermo- and operational stability in both biphasic media and neat organic solvent...
May 3, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28468200/giant-orf-on-the-nose
#19
Nurdoğan Ata, Halil Emre Göğüş, Selçuk Kiliç
Orf is a zoonotic infectious disease caused by parapoxvirus. Orf lesions are typically seen on the hand, but they have rarely been reported on the nose. Herein, the authors report a rare patient of an orf lesion on the nose of a 52-year-old man after the Muslim celebration of the feast of the sacrifice. The lesion spontaneously recovered 8 weeks after the initial appearance and showed no evidence of recurrence after 1 year of follow-up. Orf virus infections may occur more often after the celebration of the feast of the sacrifice in Muslim countries...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28466077/adenine-phosphoribosyltransferase-deficiency-a-rare-cause-of-recurrent-urolithiasis
#20
Ata Jaffer, Adrian Joyce, Philip Koenig, Chandra Shekhar Biyani
Background: Recurrent urolithiasis is troublesome for both patient and clinician, and in most cases, an underlying cause is not found. An important and underdiagnosed cause is adenine phosphoribosyltransferase (APRT) deficiency that gives rise to 2,8-dihydroxyadenine (2,8-DHA) stones. If diagnosed early, patient morbidity as well as the financial cost of treating stone recurrence can be avoided with simple medical therapy. Case Presentation: A 36-year-old white, Caucasian male with recurrent urolithiasis was found to have 2,8-DHA stones...
2017: Journal of Endourology Case Reports
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