keyword
MENU ▼
Read by QxMD icon Read
search

Spinal glioblastoma

keyword
https://www.readbyqxmd.com/read/29104839/thoracic-spinal-cord-glioblastoma-mimicking-epidural-abscess-case-report-and-literature-review
#1
Rudy Marciano, Zubair Ahammad, Victor Awuor
Spinal cord glioblastoma (SG) accounts for 1.5% of all spinal tumors and has a poor prognosis with survival ranging from 2 to 26 months from presentation. A 57-year-old male presented with one week of paraparesis and contrasted magnetic resonance imaging (MRI) findings of an epidural enhancing thoracic mass suspicious for an epidural abscess. Intraoperative and pathologic findings revealed SG. Spinal cord tumors can mimic epidural abscess on MRI. When planning to address extradural spinal pathologies, one should be cognizant of the potential for either isolated or concurrent intradural pathologies...
August 31, 2017: Curēus
https://www.readbyqxmd.com/read/29026670/rare-case-of-conus-medullaris-glioblastoma-multiforme-in-a-teenager
#2
Lakhdar Fayçal, Bougrine Mouna, El Abbadi Najia
BACKGROUND: Primary intramedullary spinal glioblastoma multiforme (GBM) lesions are very rare comprising only 1.5% of all spinal cord tumors. These lesions typically result in rapid neurological deterioration and are associated with a very poor prognosis. CASE DESCRIPTION: A 16-year-old male exhibited a slowly progressive paraparesis with urinary incontinence, ultimately resulting in paraplegia. On magnetic resonance (MR), he was diagnosed with an intramedullary GBM of the spinal cord extending from the T9 level through the conus medullaris...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28973691/high-grade-glioma-is-not-a-feature-of-neurofibromatosis-type-2-in-the-unirradiated-patient
#3
Andrew T King, Scott A Rutherford, Charlotte Hammerbeck-Ward, Simon K Lloyd, Simon M Freeman, Omar N Pathmanaban, Monica Rodriguez-Valero, Owen M Thomas, Roger D Laitt, Stavros Stivaros, Mark Kellett, D Gareth Evans
BACKGROUND: The Manchester criteria for neurofibromatosis type 2 (NF2) include a range of tumors, and gliomas were incorporated in the original description. The gliomas are now widely accepted to be predominantly spinal cord ependymomas. OBJECTIVE: To determine whether these gliomas include any cases of malignant glioma (WHO grade III and IV) through a database review. METHODS: The prospective database consists of 1253 patients with NF2. 1009 are known to be alive at last follow-up...
July 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28890010/lumbosacral-subdural-hematoma-following-glioblastoma-multiforme-resection-possible-radiographic-evidence-for-the-downward-migration-of-intracranial-blood
#4
Gabriella M Paisan, Thomas J Buell, Daniel Raper, Ashok Asthagiri
Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors. We report a case of a 75-year-old male who developed a symptomatic lumbosacral SSDH after undergoing resection of a right temporal glioblastoma multiforme. The patient subsequently recovered and was discharged home. Over the next two weeks he developed progressively worsening symptoms of lower back pain, lower extremity weakness, and urinary retention...
September 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28870453/spinal-cord-tumors-in-children-a-review-of-21-cases-treated-at-the-same-institution
#5
I Merlot, J Francois, J-C Marchal, A Joud, R Guerbouz, P Chastagner, O Klein
INTRODUCTION: Spinal cord tumors in children (SCTC) are rare with a frequent diagnostic delay. Its management is multidisciplinary and challenging due to functional implications. The position of surgery is now better established but the role and timing of chemotherapy (CT) and radiotherapy (RT) still remains under debate. Adverse effects of treatments are important to be taken into account, in the follow-up of these children. The aim of this paper was to present a series of 21 cases of SCTC treated at the same institution, to briefly present clinical features, treatments and outcome, with a special focus on spinal deformities in children with this condition...
September 1, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28840068/a-case-of-symptomatic-spinal-dural-arteriovenous-fistula-after-high-volume-lumbar-puncture
#6
Thomas Noh, Rahul Chandra, Jimmy Kim, Ian Lee
BACKGROUND: Spinal dural arteriovenous fistulas (DAVFs) are rare lesions that lead to venous congestion and ischemic injury resulting in neurologic deterioration. Here we present a patient diagnosed with glioblastoma multiforme (GBM) who became symptomatic from a spinal DAVF after a diagnostic high-volume lumbar puncture (LP). CASE DESCRIPTION: When a 72-year-old female developed partial seizures in her left upper extremity without other focal neurological deficits, she underwent a magnetic resonance imaging (MRI) scan of the brain...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28829151/validation-of-an-immunohistochemistry-assay-for-detection-of-cd155-the-poliovirus-receptor-in-malignant-gliomas
#7
Vidyalakshmi Chandramohan, Jeffrey D Bryant, Hailan Piao, Stephen T Keir, Eric S Lipp, Michaela Lefaivre, Kathryn Perkinson, Darell D Bigner, Matthias Gromeier, Roger E McLendon
CONTEXT: - The oncolytic polio-rhinovirus recombinant (PVSRIPO) has demonstrated promise in currently ongoing phase I/II clinical trials against recurrent glioblastoma and was granted breakthrough therapy designation by the Food and Drug Administration/Center for Biologics Evaluation and Research. A reliable clinical assay to document expression of the poliovirus receptor, CD155, in routinely available patient tumor samples is needed for continued clinical development of PVSRIPO oncolytic immunotherapy in primary brain tumors and beyond...
August 22, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28732416/primary-spinal-cord-glioblastoma-multiforme-a-rare-but-uniformly-fatal-neoplasm
#8
LETTER
G Lakshmi Prasad
No abstract text is available yet for this article.
August 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28634861/retraction-note-to-the-critical-role-of-srpk1-in-emt-of-human-glioblastoma-in-the-spinal-cord
#9
Zhengbu Liao, Jing Wu, Mingjun Wu, Yi Yan, Haiquan Wang, Chongjie Cheng, Wenyuan Tang
No abstract text is available yet for this article.
June 21, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28611074/cervical-spinal-glioblastoma-multiforme-in-the-elderly
#10
Dmitri Shastin, Ryan K Mathew, Azzam Ismail, Gerry Towns
Spinal glioblastoma multiforme (GBM) is uncommon, and its diagnosis may be challenging. This is especially true in the elderly population. Best management strategy remains to be defined. The purpose of this report is to document this rare condition, increase awareness (as a potential differential diagnosis) and propose treatment options in the elderly; a review of the relevant literature is included. A biopsy may be beneficial in given circumstances as cervical spinal GBM carries a better prognosis compared with intramedullary metastasis...
June 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28512411/spinal-intradural-intramedullary-dissemination-in-the-absence-of-intracranial-relapse-of-a-previously-radically-treated-temporal-lobe-glioblastoma-multiforme
#11
Lucas Serrano, Eleftherios Archavlis, Elke Januschek, Pavel Timofeev, Peter Ulrich
Intracranial glioblastoma multiforme (GBM) constitutes the most frequent and unfortunately aggressive primary central nervous system malignancy. Despite the high tendency of these tumors to show local relapse within the brain after primary therapy, dissemination into the spinal axis is an infrequent event. If spinal metastases occur they are leptomeningeal in the vast majority of cases and always in the context of intracranial progressive disease. Spinal intramedullary metastases of intracranial GBM have rarely been described to date...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28469330/profile-of-primary-pediatric-brain-and-spinal-cord-tumors-from-north-india
#12
Nadia Shirazi, Meenu Gupta, Nowneet Kumar Bhat, Braham Prakash Kalra, Ranjit Kumar, Manju Saini
BACKGROUND AND OBJECTIVE: The study was carried out to find the profile of pediatric brain and spinal cord tumors during 2006-2015 in a tertiary referral center of North India. MATERIALS AND METHODS: It was a retrospective medical record-based observational study. All children <18 years of age with confirmed histopathological diagnosis of cancer were included in the study. RESULTS: Central nervous system (CNS) tumors constituted 5.6% of all pediatric solid malignancies in our hospital...
January 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28422860/primary-spinal-glioblastoma-multiforme-a-case-report-and-review-of-the-literature
#13
Chao-Xiong Shen, Jian-Feng Wu, Wei Zhao, Zhao-Wen Cai, Ran-Ze Cai, Chun-Mei Chen
RATIONALE: Primary spinal glioblastoma multiforme (GBM) is a rare clinical entity with an aggressive course and an invariably dismal prognosis. Its clinical characteristics, radiologic and pathologic findings, and treatment protocols have been discussed in a few cases. PATIENT CONCERNS: A 15-year-old female was admitted to the neurology department with a chief complaint of progressive numbness and weakness in her left upper extremity for 3 months and neck pain for 1 month...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28377242/primary-spinal-cord-glioblastoma-multiforme-a-retrospective-study-of-patients-at-a-single-institution
#14
Xing Cheng, Silong Lou, Siqing Huang, Haifeng Chen, Jiagang Liu
BACKGROUND AND OBJECTIVE: Primary spinal cord (PSC) glioblastoma multiforme (GBM) is extremely rare and accounts for only 1.5% of all spinal cord tumors. Therefore, its treatment is still ill defined. To elucidate prognostic factors, we performed a single-institutional retrospective review of the largest series to date of patients with PSC GBM who underwent surgical resection in West China Hospital between 2008 and 2014. A total of 14 patients with PSC GBM were reviewed. METHODS: Demographic, operative, and postoperative factors were recorded...
October 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28353599/glioblastoma-multiforme-in-conus-medullaris-with-intracranial-metastasis-after-postoperative-adjuvant-therapy
#15
Chengrui Yan, Xiangyi Kong, Hua Yin, Yu Wang, Huayu He, Hui Zhang, Jun Gao, Yongning Li, Wenbin Ma
Spinal glioblastoma multiforme is not common among spinal cord tumors. According to our literature review, only 27 cases originating from the conus medullaris were reported. We herein reported a case of a 10-year-old child diagnosed with glioblastoma multiforme. The patient received adjuvant radiotherapy and standard temozolomide chemotherapy after total excision. Intracranial lesions were found 1 month after postoperative adjuvant therapy. We described the clinical characteristics and postoperative therapy of the patient, and reviewed all of the published cases of conus medullaris glioblastoma...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28343918/primary-lung-metastasis-of-glioblastoma-multiforme-with-epidural-spinal-metastasis-case-report
#16
Haydn A Hoffman, Charles H Li, Richard G Everson, Jennifer L Strunck, William H Yong, Daniel C Lu
Extracranial metastasis of glioblastoma multiforme (GBM) is rare, but has recently been reported with increasing frequency. GBM metastases typically present after a biopsy or resection of the primary tumor. An otherwise healthy 54year-old woman presented with recurring pleural effusions originally believed to be from a primary lung malignancy. The patient subsequently experienced a generalized tonic clonic seizure and a right temporal brain mass was discovered. The patient later developed weakness and radiculopathy, and an extramedullary extradural mass spreading from C7 to T6 was discovered...
July 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28242994/-drop-metastases-from-an-operated-case-of-intracranial-anaplastic-ependymoma-identified-on-fluoro-2-deoxyglucose-positron-emission-tomography-computed-tomography
#17
Piyush Chandra, Nilendu Purandare, Sneha Shah, Archi Agrawal, Venkatesh Rangarajan
The seeding of tumor through cerebrospinal fluid (CSF) from primary intracranial tumors is very rare, often goes undetected, and is usually identified only on autopsy. CSF cytology along with magnetic resonance imaging constitutes the standard approach of diagnosing this grave condition. Use of fluoro-2-deoxyglucose positron emission tomography/computed tomography (PET/CT) in indentifying spinal metastases from primary intracranial malignancies is very limited and has been reported in patients with metastatic glioblastoma multiforme and medulloblastomas...
January 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28230061/neurofibromatosis-type-1
#18
REVIEW
David H Gutmann, Rosalie E Ferner, Robert H Listernick, Bruce R Korf, Pamela L Wolters, Kimberly J Johnson
Neurofibromatosis type 1 is a complex autosomal dominant disorder caused by germline mutations in the NF1 tumour suppressor gene. Nearly all individuals with neurofibromatosis type 1 develop pigmentary lesions (café-au-lait macules, skinfold freckling and Lisch nodules) and dermal neurofibromas. Some individuals develop skeletal abnormalities (scoliosis, tibial pseudarthrosis and orbital dysplasia), brain tumours (optic pathway gliomas and glioblastoma), peripheral nerve tumours (spinal neurofibromas, plexiform neurofibromas and malignant peripheral nerve sheath tumours), learning disabilities, attention deficits, and social and behavioural problems, which can negatively affect quality of life...
February 23, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28156189/feline-glioma-a-retrospective-study-and-review-of-the-literature
#19
Daniel R Rissi, Andrew D Miller
Case series summary This study aimed to evaluate the pathologic and diagnostic features of 13 cases of feline glioma diagnosed at two veterinary diagnostic institutions over 16 years. A retrospective search was conducted using the laboratory information system. Selected cases were reviewed, tumors were classified according to the 2007 World Health Organization Classification of Tumours of the Central Nervous System, and tissue sections were submitted to an immunohistochemistry panel for further characterization...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28108463/targeting-glioblastoma-with-car-t-cells
#20
(no author information available yet)
CAR T cells targeting IL13Rα2 proved effective against recurrent multifocal leptomeningeal glioblastoma, according to a case report. Direct delivery of the therapy into the cerebrospinal fluid was well tolerated, completely eliminating the patient's brain and spinal tumors for 7.5 months, during which the patient resumed his normal activities.
January 20, 2017: Cancer Discovery
keyword
keyword
42824
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"