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https://www.readbyqxmd.com/read/28732272/screening-of-the-open-scaffolds-collection-from-compounds-australia-identifies-a-new-chemical-entity-with-anthelmintic-activities-against-different-developmental-stages-of-the-barber-s-pole-worm-and-other-parasitic-nematodes
#1
Sarah Preston, Yaqing Jiao, Jonathan B Baell, Jennifer Keiser, Simon Crawford, Anson V Koehler, Tao Wang, Moana M Simpson, Ray M Kaplan, Karla J Cowley, Kaylene J Simpson, Andreas Hofmann, Abdul Jabbar, Robin B Gasser
The discovery and development of novel anthelmintic classes is essential to sustain the control of socioeconomically important parasitic worms of humans and animals. With the aim of offering novel, lead-like scaffolds for drug discovery, Compounds Australia released the 'Open Scaffolds' collection containing 33,999 compounds, with extensive information available on the physicochemical properties of these chemicals. In the present study, we screened 14,464 prioritised compounds from the 'Open Scaffolds' collection against the exsheathed third-stage larvae (xL3s) of Haemonchus contortus using recently developed whole-organism screening assays...
May 28, 2017: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/28731633/australian-consumer-awareness-of-health-benefits-associated-with-vegetable-consumption
#2
Reetica Rekhy, Aila Khan, Jocelyn Eason, Hazel Mactavish-West, Carolyn Lister, Robyn Mcconchie
AIM: The present study investigated the perceived health benefits of specific vegetable consumption to guide the use of nutrition and health claims on vegetable marketing collateral. METHODS: Free elicitation and consumer ranking data were collected through an online survey of 1000 adults from across Australia and analysed for the perceived importance of vegetables in the daily diet, number of serves consumed per day, knowledge about health-related benefits of specific vegetables and perceived health benefits of vegetable consumption...
April 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731625/dietitians-association-of-australia-34th-national-conference-cultivating-fresh-evidence-hobart-tasmania-australia-18-20-may-2017
#3
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731606/feasibility-of-home-based-dietetic-intervention-to-improve-the-nutritional-status-of-older-adults-post-hospital-discharge
#4
Aliza Haslinda Hamirudin, Karen Walton, Karen Charlton, Amanda Carrie, Linda Tapsell, Marianna Milosavljevic, Glen Pang, Jan Potter
AIM: To determine if a model of home-based dietetic care improves dietary intake and weight status in a specific group of older adults post-hospitalisation. METHODS: The Department of Veterans' Affairs clients aged 65 years and over were recruited from hospitals in a regional area of New South Wales, Australia (n = 32 men, n = 36 women). Nutritional status was assessed at home at baseline (within two weeks post-discharge) and three months post-discharge using a diet history, a food frequency checklist and Mini Nutritional Assessment (MNA)...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731605/optimising-the-effectiveness-of-diabetes-education-in-an-east-asian-population
#5
T S T Choi, K Z Walker, C B Lombard, C Palermo
AIM: To explore the collective patterns of learning behaviours and preferences of Chinese people during diabetes education. The study was carried out across three countries and aimed to identify strategies that could be used to tailor diabetes education to Chinese people. METHODS: A case study approach was undertaken in three countries (Australia, China and Singapore) using participant observations and qualitative interviews. Purposive sampling was used to select field sites before a snowball technique was employed to identify relevant interviewees...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731602/accuracy-and-precision-of-estimation-equations-to-predict-net-endogenous-acid-excretion-using-the-australian-food-database
#6
Benjamin H Parmenter, Gary J Slater, Lynda A Frassetto
AIM: The gold standard of measurement for net endogenous acid production (NEAP) is net acid excretion (NAE), a test that is not readily available, and consequently, estimative equations by Remer and Manz and Frassetto et al. are often used. These equations rely on nutrient databases and it is recommended that their validity be assessed using a country's database before their application in research in that country. We sought to delineate the accuracy and precision of these estimation equations using the Australian food database...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731601/telephone-delivered-weight-management-services-in-the-hospital-outpatient-setting-decision-makers-perceptions-of-their-use-in-routine-practice
#7
Megan E Whelan, Ana D Goode, Ingrid J Hickman, Elizabeth G Eakin, Marina M Reeves
AIM: Providing effective weight management services to the growing number of overweight or obese hospital patients necessitates long-term service provision; however, it is arguably not within the acute-care hospital remit to provide such extended services. Referral to community-based programs is required to provide continuing weight management services. The Get Healthy Service is a free six-month, telephone-delivered lifestyle program, now offered in several states of Australia with potential for wide population reach...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731597/reliability-and-relative-validity-of-a-diet-index-score-for-adults-derived-from-a-self-reported-short-food-survey
#8
Gilly A Hendrie, Megan A Rebuli, Rebecca K Golley
AIM: Assess the reliability and relative validity of a diet index score for adults derived using a 38-item online survey. METHODS: The short food survey (SFS) measured 'usual' intake of seven food groups, three food choice indicators and variety; and was completed by 61 adults aged 19-50 years from Adelaide, Australia. A score was applied to assess compliance with the 2013 Australian Dietary Guidelines. Reliability of the survey was measured between two administrations one week apart; and validity by comparing the first administration to the average of three 24-hour dietary recalls...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731288/radiation-therapists-perspectives-on-participating-in-research
#9
Georgia K B Halkett, Melissa Berg, Martin A Ebert, David Cutt, Michael Davis, Desley Hegney, Michael House, Michelle Judson, Rachel Kearvell, Michele Krawiec, Leanne Lester, Sharon Maresse, Peter McLoone, Jan McKay
INTRODUCTION: The objectives of this research were to: (1) determine the extent of Australian radiation therapists (RTs) research participation; (2) evaluate the impact of research involvement on career perceptions (3) explore which research topics require investigation and (4) identify benefits and barriers to research participation. METHODS: This study used mixed methods to collect qualitative and quantitative data using an online survey from a larger workforce study of RTs and radiation oncology medical physicists...
July 21, 2017: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/28731051/neurotropic-melanoma-an-analysis-of-the-clinicopathological-features-management-strategies-and-survival-outcomes-for-671-patients-treated-at-a-tertiary-referral-center
#10
Alexander H R Varey, Chris Goumas, Angela M Hong, Graham J Mann, Gerald B Fogarty, Jonathan R Stretch, Robyn P M Saw, Andrew J Spillane, Kerwin F Shannon, Kenneth J Lee, Michael J Quinn, John F Thompson, Richard A Scolyer
Neurotropic cutaneous melanoma is a rare melanoma subtype that invades nerves and is often associated with desmoplastic melanoma. Limited data suggest that it has a greater propensity to recur locally, but it is unknown whether its behavior differs from that of other melanoma subtypes, including desmoplastic melanoma. We investigated clinicopathological predictors of outcome in a cohort of 671 patients with neurotropic melanoma to develop evidence-based management recommendations. Patients with primary neurotropic melanoma diagnosed from 1985 to 2013 were identified from the Melanoma Institute Australia database, along with a control cohort of 718 non-neurotropic melanoma patients...
July 21, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28730851/agomelatine-for-the-treatment-of-generalized-anxiety-disorder
#11
Massimiliano Buoli, Silvia Grassi, Marta Serati, A Carlo Altamura
Agomelatine is a melatonergic antidepressant, approved for the treatment of Major Depressive Disorder (MDD) in Europe and Australia, but not in the United States. This compound seems to be promising in the short-term and maintenance treatment of Generalized Anxiety Disorder (GAD). Areas covered: This paper presents an evaluation of the available data about the clinical efficacy and tolerability of agomelatine in the treatment of GAD. Expert opinion: First-line GAD treatments are limited by high rates of lack of clinical response...
July 21, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28730615/vulvar-cancer-in-high-income-countries-increasing-burden-of-disease
#12
Yoon-Jung Kang, Megan Smith, Ellen Barlow, Kate Coffey, Neville Hacker, Karen Canfell
The aim of this study was to assess trends in the age-specific incidence of vulvar cancer in 13 high-income countries satisfying a priori conditions regarding the availability of cancer registry data over a 20 year period; these were Canada, USA, 9 European countries, Australia and Japan. Five-yearly incidence and population at risk were obtained from Cancer Incidence in Five Continents for the years 1988-1992 (Volume 7) to 2003-2007 (Volume 10). The 5-yearly average percent change (AvPC) over the 20-year period and standardised rate ratios (SRRs) for 2003-2007 vs...
July 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28729921/an-outbreak-of-foodborne-norovirus-gastroenteritis-linked-to-a-restaurant-in-melbourne-australia-2014
#13
Shaun P Coutts, Kaye Sturge, Karin Lalor, John A Marshall, Leesa D Bruggink, Nela Subasinghe, Marion Easton
INTRODUCTION: In May 2014 an outbreak of norovirus occurred among patrons of a restaurant in Melbourne, Australia. Investigations were conducted to identify the infectious agent, mode of transmission and source of illness, and to implement controls to prevent further transmission. METHODS: A retrospective case-control study was conducted to test the hypothesis that food served at the restaurant between 9 and 15 May 2014 was the vehicle for infection. A structured questionnaire was used to collect demographic, illness and food exposure data from study participants...
April 2017: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/28729920/annual-vaccine-preventable-disease-report-for-new-south-wales-australia-2014
#14
Nathan Saul, Robin Gilmour, Paula Spokes
This report provides an epidemiological description of selected vaccine-preventable diseases in New South Wales (NSW), Australia, for 2014 to inform ongoing disease monitoring and control efforts. A trend of increasing pertussis notifications was observed, beginning midway through 2014 with the highest disease rates in the 5-9 year age group. Measles notifications increased to 67 cases in 2014 from 34 cases in 2013. Measles cases were associated with travel-related importations-predominantly from the Philippines-and secondary transmission increased compared to 2013 involving three main disease clusters...
April 2017: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/28729781/advanced-hysteroscopic-surgery-quality-assurance-in-teaching-hospitals
#15
REVIEW
Mark M S Erian, Glenda R McLaren, Anna-Marie Erian
Advanced hysteroscopic surgery (AHS) is a vitally important technique in the armamentarium for the management of many day-to-day clinical problems, such as menorrhagia, surgical excision of uterine myomata and septa in the management of female infertility, hysteroscopic excision of chronically retained products of conception (placenta accreta), and surgical removal of intramural ectopic pregnancy. In today's climate of accountability, it is necessary that gynecologists take a more active role in assuring the quality of their work...
April 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28729747/do-more-of-those-in-misery-suffer-from-poverty-unemployment-or-mental-illness
#16
Sarah Flèche, Richard Layard
Studies of deprivation usually ignore mental illness. This paper uses household panel data from the USA, Australia, Britain and Germany to broaden the analysis. We ask first how many of those in the lowest levels of life-satisfaction suffer from unemployment, poverty, physical ill health, and mental illness. The largest proportion suffers from mental illness. Multiple regression shows that mental illness is not highly correlated with poverty or unemployment, and that it contributes more to explaining the presence of misery than is explained by either poverty or unemployment...
February 2017: Kyklos: International Review for Social Sciences
https://www.readbyqxmd.com/read/28729733/extreme-coastal-erosion-enhanced-by-anomalous-extratropical-storm-wave-direction
#17
Mitchell D Harley, Ian L Turner, Michael A Kinsela, Jason H Middleton, Peter J Mumford, Kristen D Splinter, Matthew S Phillips, Joshua A Simmons, David J Hanslow, Andrew D Short
Extratropical cyclones (ETCs) are the primary driver of large-scale episodic beach erosion along coastlines in temperate regions. However, key drivers of the magnitude and regional variability in rapid morphological changes caused by ETCs at the coast remain poorly understood. Here we analyze an unprecedented dataset of high-resolution regional-scale morphological response to an ETC that impacted southeast Australia, and evaluate the new observations within the context of an existing long-term coastal monitoring program...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729670/forest-edge-disturbance-increases-rattan-abundance-in-tropical-rain-forest-fragments
#18
Mason J Campbell, Will Edwards, Ainhoa Magrach, Susan G Laurance, Mohammed Alamgir, Gabriel Porolak, William F Laurance
Human-induced forest fragmentation poses one of the largest threats to global diversity yet its impact on rattans (climbing palms) has remained virtually unexplored. Rattan is arguably the world's most valuable non-timber forest product though current levels of harvesting and land-use change place wild populations at risk. To assess rattan response to fragmentation exclusive of harvesting impacts we examined rattan abundance, demography and ecology within the forests of northeastern, Australia. We assessed the community abundance of rattans, and component adult (>3 m) and juvenile (≤3 m) abundance in five intact forests and five fragments (23-58 ha) to determine their response to a range of environmental and ecological parameters...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729312/protocol-a-grounded-theory-of-recovery-perspectives-of-adolescent-users-of-mental-health-services
#19
Lucianne Palmquist, Sue Patterson, Analise O'Donovan, Graham Bradley
INTRODUCTION: Policies internationally endorse the recovery paradigm as the appropriate foundation for youth mental health services. However, given that this paradigm is grounded in the views of adults with severe mental illness, applicability to youth services and relevance to young people is uncertain, particularly as little is known about young people's views. A comprehensive understanding of the experiences and expectations of young people is critical to developing youth mental health services that are acceptable, accessible, effective and relevant...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28729258/complete-genome-sequence-of-a-highly-divergent-dengue-virus-type-2-strain-imported-into-australia-from-sabah-malaysia
#20
Alyssa T Pyke, Bixing Huang, David Warrilow, Peter R Moore, Jamie McMahon, Bruce Harrower
In 2015, a female patient returning to Australia from Sabah, Malaysia, was diagnosed with a suspected sylvatic dengue virus type 2 (DENV-2) infection, becoming the second case of imported highly divergent dengue virus infection recorded in Australia. We describe here the complete genome sequencing of the DENV-2 strain isolated from this patient.
July 20, 2017: Genome Announcements
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