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https://www.readbyqxmd.com/read/28812041/anthropometric-and-skeletal-parameters-predict-2-strand-semitendinosus-tendon-size-in-double-bundle-anterior-cruciate-ligament-reconstruction
#1
Daisuke Chiba, Eiichi Tsuda, Shizuka Sasaki, Xizhe Liu, Yasuyuki Ishibashi
BACKGROUND: Few studies have examined whether skeletal parameters predict hamstring graft size during anterior cruciate ligament reconstruction (ACLR). PURPOSE/HYPOTHESIS: The purpose of this study was to examine whether preoperative anthropometric and radiographic skeletal parameters could predict hamstring graft size during ACLR. We hypothesized that both anthropometric and skeletal parameters can be used to predict graft size in our double-bundle procedure and that the use of skeletal parameters will improve the accuracy of graft size prediction...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28749158/a-wait-list-controlled-study-of-a-trauma-focused-cognitive-behavioral-treatment-for-intermittent-explosive-disorder-in-timor-leste
#2
Kalhari Hewage, Zachary Steel, Mohammed Mohsin, Alvin Kuowei Tay, Jose Carlos De Oliveira, Marcio Da Piedade, Natalino Tam, Derrick Silove
We tested a trauma-focused, cognitive-behavior therapy treatment (TF-CBT-anger) for intermittent explosive disorder (IED) and related dimensions of anger adapted to the local culture in postconflict Timor-Leste. The intention-to-treat sample (n = 78) comprised Timorese nationals (women = 49; men = 29), ages 18 years and older, meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed.) criteria for IED, with equal numbers (n = 39 each) being randomized to the treatment group (TG) and wait-list (WL)...
July 27, 2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28737281/in-situ-evaluation-of-color-stability-and-hardness-decrease-of-resin-based-composites
#3
Juliana Silva Ribeiro, Sonia Luque Peralta, Vinícius Esteves Salgado, Rafael Guerra Lund
OBJECTIVE: To determine the color stability (CS) and hardness' decrease (HD) of two commercial resin-based composites (RBCs), after in situ staining conditions (SC). METHODS: Six disc-shaped specimens (6 × 2 mm) of two RBCs-Filtek Z350 XT (FZX) and IPS Empress Direct (IED)-were randomly distributed into palatal devices. Eight volunteers (aged 20-30 years) participated in this study. The in situ SC consisted of 400 mL consumption (2 × 200 mL/day) of water, orange juice, cola soda, and coffee and 140 mL consumption of red wine, 10 days each...
July 24, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28716473/characteristics-of-mandibular-injuries-caused-by-bullets-and-improvised-explosive-devices-a-comparative-study
#4
S Y H Bede, W K Ismael, D Al-Assaf
The purpose of this study was to investigate the difference in mandibular trauma caused by two mechanisms for the delivery of missile injuries: firearms and improvised explosive devices (IEDs). The data investigated included sex, age, mechanism of injury, and other clinical and radiographic manifestations. Seventy consecutive patients, predominantly male, with a mean age of 28.6±14 years (range 2-60 years) were enrolled: 38 patients (54.3%) sustained mandibular fractures caused by bullet injuries and 32 patients (45...
July 14, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28692859/an-experimental-study-addressing-the-use-of-geoforensic-analysis-for-the-exploitation-of-improvised-explosive-devices-ieds
#5
Beth Wilks, Ruth M Morgan, Neil L Rose
The use of geoforensic analysis in criminal investigations is continuing to develop, with the diversification of analytical techniques, many of which are semi-automated, facilitating prompt analysis of large sample sets at a relatively low cost. Whilst micro-scale geoforensic analysis has been shown to assist criminal investigations including homicide (Concheri et al., 2011 [1]), wildlife crime (Morgan et al., 2006 [2]), illicit drug distribution (Stanley, 1992 [3]), and burglary (Mildenhall, 2006 [4]), its application to the pressing international security threat posed by Improvised Explosive Devices (IEDs) is yet to be considered...
July 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28648620/iron-overload-induces-hypogonadism-in-male-mice-via-extrahypothalamic-mechanisms
#6
Chiara Macchi, Liliana Steffani, Roberto Oleari, Antonella Lettieri, Luca Valenti, Paola Dongiovanni, Antonio Romero-Ruiz, Manuel Tena-Sempere, Anna Cariboni, Paolo Magni, Massimiliano Ruscica
INTRODUCTION: Iron overload leads to multiple organ damage including endocrine organ dysfunctions. Hypogonadism is the most common non-diabetic endocrinopathy in primary and secondary iron overload syndromes. AIM: To explore the molecular determinants of iron overload-induced hypogonadism with specific focus on hypothalamic derangements. A dysmetabolic male murine model fed iron-enriched diet (IED) and cell-based models of gonadotropin-releasing hormone (GnRH) neurons were used...
October 15, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28635556/executive-control-in-schizophrenia-a-preliminary-study-on-the-moderating-role-of-comt-val158met-for-comorbid-alcohol-and-substance-use-disorders
#7
Giuseppe Carrà, Gabriella Nicolini, Cristina Crocamo, Annamaria Lax, Francesca Amidani, Francesco Bartoli, Filippo Castellano, Alessia Chiorazzi, Giulia Gamba, Costanza Papagno, Massimo Clerici
BACKGROUND: A functional polymorphism in the catechol-O-methyltransferase (COMT) gene (Val158Met) appears to influence cognition in people with alcohol/substance use disorders (AUD/SUD) and in those with psychosis. METHODS: To explore the potential moderating effect of these factors, a cross-sectional study was conducted, randomly recruiting subjects with DSM-IV diagnosis of schizophrenia. AUD/SUD was rigorously assessed, as well as COMT Val158Met polymorphism. Executive control functioning was measured using the Intra-Extra Dimensional Set Shift (IED)...
February 14, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28633091/cyclic-alternating-pattern-and-interictal-epileptiform-discharges-during-morning-sleep-after-sleep-deprivation-in-temporal-lobe-epilepsy
#8
Filippo Sean Giorgi, Michelangelo Maestri, Melania Guida, Luca Carnicelli, Lorenzo Caciagli, Raffaele Ferri, Ubaldo Bonuccelli, Enrica Bonanni
PURPOSE: Sleep deprivation (SD) increases the occurrence of interictal epileptiform discharges (IED) compared to basal EEG in temporal lobe epilepsy (TLE). In adults, EEG after SD is usually performed in the morning after SD. We aimed to evaluate whether morning sleep after SD bears additional IED-inducing effects compared with nocturnal physiological sleep, and whether changes in sleep stability (described by the cyclic alternating pattern-CAP) play a significant role. METHODS: Adult patients with TLE underwent in-lab night polysomnography (n-PSG) and, within 7days from n-PSG, they underwent also a morning EEG after night SD (SD-EEG)...
June 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28629642/splenic-vein-reconstruction-is-unnecessary-in-pancreatoduodenectomy-combined-with-resection-of-the-superior-mesenteric-vein-portal-vein-confluence-according-to-short-term-outcomes
#9
Haruyoshi Tanaka, Akimasa Nakao, Kenji Oshima, Kiyotsugu Iede, Yukiko Oshima, Hironobu Kobayashi, Yasunori Kimura
BACKGROUND: Superior mesenteric vein-portal vein confluence resection combined with pancreatoduodenectomy (SMPVrPD) is occasionally required for resection of pancreatic head tumors. It remains unclear whether such situations require splenic vein (SV) reconstruction for decompression of left-sided portal hypertension (LSPH). METHODS: The data from 93 of 104 patients who underwent pancreatoduodenectomy (PD) for pancreatic head malignancies were reviewed. Surgical outcomes in three groups-standard PD (control group), PD combined with vascular resection and SV preservation (SVp group), and SMPVrPD with SV resection (SVr group)-were compared...
June 16, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28621543/estimating-particulate-exposure-from-modern-municipal-waste-incinerators-in-great-britain
#10
Philippa Douglas, Anna Freni-Sterrantino, Maria Leal Sanchez, Danielle C Ashworth, Rebecca E Ghosh, Daniela Fecht, Anna Font, Marta Blangiardo, John Gulliver, Mireille B Toledano, Paul Elliott, Kees de Hoogh, Gary W Fuller, Anna L Hansell
Municipal Waste Incineration (MWI) is regulated through the European Union Directive on Industrial Emissions (IED), but there is ongoing public concern regarding potential hazards to health. Using dispersion modeling, we estimated spatial variability in PM10 concentrations arising from MWIs at postcodes (average 12 households) within 10 km of MWIs in Great Britain (GB) in 2003-2010. We also investigated change points in PM10 emissions in relation to introduction of EU Waste Incineration Directive (EU-WID) (subsequently transposed into IED) and correlations of PM10 with SO2, NOx, heavy metals, polychlorinated dibenzo-p-dioxins/furan (PCDD/F), polycyclic aromatic hydrocarbon (PAH) and polychlorinated biphenyl (PCB) emissions...
June 16, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28605741/electroencephalography-patterns-and-prognosis-in-acute-ischemic-stroke
#11
Fabricio O Lima, João A G Ricardo, Ana C Coan, Diogo C Soriano, Wagner M Avelar, Li L Min
BACKGROUND AND PURPOSE: The prognostic significance of interictal epileptiform discharges (IED) and periodic patterns (PP) after ischemic stroke has not been assessed. We sought to test whether IED and PP, detected on standard Electroencephalography (EEG) performed during the acute phase of ischemic stroke are associated with a worse functional outcome. METHODS: One-hundred-fifty-seven patients 18 years or older with a diagnosis of acute ischemic stroke presenting within 72 h from stroke onset were prospectively enrolled and followed...
June 13, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28586147/epileptic-networks-in-action-synchrony-between-distant-hemodynamic-responses
#12
Hui Ming Khoo, Nicolás von Ellenrieder, Natalja Zazubovits, François Dubeau, Jean Gotman
OBJECTIVE: Structural and functional imaging studies in focal epilepsy often reveal distributed regions of abnormality. These are interpreted as representing the existence of epileptic networks but the presence of actual neuronal interactions between these regions has not been demonstrated. We sought to determine if the distributed hemodynamic responses often seen in fMRI studies of scalp interictal epileptic discharges (IEDs) actually correspond to synchronized neuronal activities when examining the intracerebral EEG (iEEG) at distant nodes of the network...
June 6, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28583491/adaptation-validity-and-reliability-of-the-preschool-language-scale-fifth-edition-pls-5-in-the-turkish-context-the-turkish-preschool-language-scale-5-tpls-5
#13
A Sanem Sahli, Erol Belgin
INTRODUCTION: Speech and language assessment is very important in early diagnosis of children with hearing and speech disorders. Aim of this study is to determine the validity and reliability of Preschool Language Scale (5th edition) test with its Turkish translation and adaptation. METHODS AND MATERIALS: Our study is conducted on 1320 children aged between 0-7 years 11 months. While 1044 of these children have normal hearing, language and speech development, 276 of them have receptive and/or expressive language disorder...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28549276/different-seizure-onset-patterns-in-mesiotemporal-lobe-epilepsy-have-a-distinct-interictal-signature
#14
Birgit Frauscher, Nicolás von Ellenrieder, François Dubeau, Jean Gotman
OBJECTIVE: Experimental research demonstrated that distinct underlying mechanisms go along with different seizure-onset patterns on EEG. These different mechanisms may reflect different tissue abnormalities which, we hypothesize, could also be reflected in morphological differences in the interictal epileptic and background EEG activity. METHODS: We searched our database of intracranial EEG recordings for mesiotemporal lobe epilepsy patients with either predominant low-voltage fast activity (LVF) or periodic spiking (PS)...
July 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28539210/design-and-testing-of-a-controlled-electromagnetic-spinal-cord-impactor-for-use-in-large-animal-models-of-acute-traumatic-spinal-cord-injury
#15
Rory J Petteys, Steven M Spitz, Hasan Syed, R Andrew Rice, Rachel Sarabia-Estrada, C Rory Goodwin, Daniel M Sciubba, Brett A Freedman
BACKGROUND: Spinal cord injury (SCI) causes debilitating neurological dysfunction and has been observed in warfighters injured in IED blasts. Clinical benefit of SCI treatment remains elusive and better large animal models are needed to assess treatment options. Here, we describe a controlled electromagnetic spinal cord impactor for use in large animal models of SCI. METHODS: A custom spinal cord impactor and platform were fabricated for large animals (e.g., pig, sheep, dog, etc...
May 20, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28531810/a-novel-scheme-for-the-validation-of-an-automated-classification-method-for-epileptic-spikes-by-comparison-with-multiple-observers
#16
COMPARATIVE STUDY
Niraj K Sharma, Carlos Pedreira, Maria Centeno, Umair J Chaudhary, Tim Wehner, Lucas G S França, Tinonkorn Yadee, Teresa Murta, Marco Leite, Sjoerd B Vos, Sebastien Ourselin, Beate Diehl, Louis Lemieux
OBJECTIVE: To validate the application of an automated neuronal spike classification algorithm, Wave_clus (WC), on interictal epileptiform discharges (IED) obtained from human intracranial EEG (icEEG) data. METHOD: Five 10-min segments of icEEG recorded in 5 patients were used. WC and three expert EEG reviewers independently classified one hundred IED events into IED classes or non-IEDs. First, we determined whether WC-human agreement variability falls within inter-reviewer agreement variability by calculating the variation of information for each classifier pair and quantifying the overlap between all WC-reviewer and all reviewer-reviewer pairs...
July 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28510905/zoomed-mri-guided-by-combined-eeg-meg-source-analysis-a-multimodal-approach-for-optimizing-presurgical-epilepsy-work-up-and-its-application-in-a-multi-focal-epilepsy-patient-case-study
#17
Ü Aydin, S Rampp, A Wollbrink, H Kugel, J -H Cho, T R Knösche, C Grova, J Wellmer, C H Wolters
In recent years, the use of source analysis based on electroencephalography (EEG) and magnetoencephalography (MEG) has gained considerable attention in presurgical epilepsy diagnosis. However, in many cases the source analysis alone is not used to tailor surgery unless the findings are confirmed by lesions, such as, e.g., cortical malformations in MRI. For many patients, the histology of tissue resected from MRI negative epilepsy shows small lesions, which indicates the need for more sensitive MR sequences...
July 2017: Brain Topography
https://www.readbyqxmd.com/read/28499856/measuring-soldier-performance-during-the-patrol-exertion-multitask-preliminary-validation-of-a-post-concussive-functional-return-to-duty-metric
#18
Matthew Scherer, Margaret M Weightman, Mary Vining Radomski, Laurel Smith, Marsha Finkelstein, Amy Cecchini, Kristin Jensen Heaton, Karen McCulloch
OBJECTIVE: To assess the discriminant validity of the Patrol-Exertion Multitask (PEMT), a novel, multi-domain, functional return-to-duty clinical assessment for Active Duty military personnel. DESIGN: Measurement development study SETTING: Non-clinical indoor testing facility, Fort Bragg NC PARTICIPANTS: 51 healthy control (HC) Service Members and 33 military personnel with persistent post-concussive symptoms receiving rehabilitation (mTBI) INTERVENTION: Not applicable MAIN OUTCOME MEASURES: Known-groups discriminant validity was evaluated by comparing performance on the PEMT in two groups of Active Duty SM, HC and personnel with mTBI residual symptoms...
May 9, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28462941/%C3%AE-adrenoceptor-blockade-in-the-basolateral-amygdala-but-not-the-medial-prefrontal-cortex-rescues-the-immediate-extinction-deficit
#19
Thomas F Giustino, Jocelyn R Seemann, Gillian M Acca, Travis D Goode, Paul J Fitzgerald, Stephen Maren
Early psychological interventions, such as exposure therapy, rely on extinction learning to reduce the development of stress- and trauma-related disorders. However, recent research suggests that extinction often fails to reduce fear when administered soon after trauma. This immediate extinction deficit (IED) may be due to stress-induced dysregulation of neural circuits involved in extinction learning. We have shown that systemic β-adrenoceptor blockade with propranolol rescues the IED, but impairs delayed extinction...
May 2, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28455849/coupling-i-125-permanent-implant-prostate-brachytherapy-monte-carlo-dose-calculations-with-radiobiological-models
#20
Nelson Miksys, Mehan Haidari, Eric Vigneault, Andre-Guy Martin, Luc Beaulieu, Rowan M Thomson
PURPOSE: To investigate the coupling of radiobiological models with patient-specific Monte Carlo (MC) dose calculations for permanent implant prostate brachytherapy (PIPB). To compare radiobiological indices evaluated with different radiobiological models using MC and simulated AAPM TG-43 dose calculations. METHODS: Three-dimensional dose distributions previously computed using MC techniques with two types of patient models, TG43sim (AAPM TG-43 water-based conditions) and MCDmm (realistic tissues and interseed effects), for 613 PIPB patients are coupled with biological dose and tumour control probability (TCP) models...
August 2017: Medical Physics
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