Yang-Xi Hu, Hong-Min You, Chang-Zhen Ren, Bo-Wen Hu, Lu-Jun Zhang, Yan-Da Zhang, Zhi-Qing He, Ru Ding, Zhi-Fu Guo, Chun Liang
BACKGROUND: The compound Danshen Dripping Pill (CDDP), which is a mixture of extracts from Radix Salviae and Panax notoginseng, is a patented traditional Chinese medicine that is widely used in multiple countries for relieving coronary heart disease (CHD), but its pharmacological mechanism has not been fully elucidated. In this study, we screened the key pharmacological pathways and targets of CDDP that act on CHD using a network pharmacology-based strategy, and the angiogenic activity of CDDP was directly visually investigated in zebrafish embryos in vivo...
April 22, 2022: BMC complementary medicine and therapies