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https://www.readbyqxmd.com/read/29232662/a-multicenter-clinical-evaluation-of-data-logging-in-cochlear-implant-recipients-using-automated-scene-classification-technologies
#1
Eliana Cristofari, Domenico Cuda, Alessandro Martini, Francesca Forli, Diego Zanetti, Diego Di Lisi, Pasquale Marsella, Daniele Marchioni, Vincenzo Vincenti, Claudia Aimoni, Gaetano Paludetti, Maria Grazia Barezzani, Carlo Antonio Leone, Nicola Quaranta, Marco Bianchedi, Livio Presutti, Antonio Della Volpe, Luca Oscar Redaelli de Zinis, Italo Cantore, Giuseppe Nicolò Frau, Eva Orzan, Francesco Galletti, Silvano Vitale, Ferdinando Raso, Maurizio Negri, Franco Trabalzini, Walter Livi, Lucia Oriella Piccioni, Giampietro Ricci, Paolo Malerba
Currently, there are no studies assessing everyday use of cochlear implant (CI) processors by recipients by means of objective tools. The Nucleus 6 sound processor features a data logging system capable of real-time recording of CI use in different acoustic environments and under various categories of loudness levels. In this study, we report data logged for the different scenes and different loudness levels of 1,366 CI patients, as recorded by SCAN. Monitoring device use in cochlear implant recipients of all ages provides important information about the listening conditions encountered in recipients' daily lives that may support counseling and assist in the further management of their device settings...
December 13, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29232325/utility-of-electronic-medical-records-in-community-rheumatology-practice-for-assessing-quality-of-care-indicators-for-gout-a-feasibility-study
#2
Augusto Estrada, Nicole W Tsao, Alyssa Howren, John M Esdaile, Kamran Shojania, Mary A De Vera
OBJECTIVES: With comprehensive capture of information on patient encounters, electronic medical records (EMRs) may have utility for assessing adherence to quality indicators (QIs) in gout. Our objectives were to translate 10 previously established gout QIs into relevant EMR data and evaluate and describe the feasibility of using EMRs to assess gout QIs. METHODS: Using EMRs from 3 community rheumatology practices in Vancouver, British Columbia, Canada, we identified gout patients seen between January 1, 2012, and December 31, 2013...
December 12, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29232312/improvement-of-smoking-abstinence-rates-with-increased-varenicline-dosage-a-propensity-score-matched-analysis
#3
Maher Karam-Hage, George Kypriotakis, Jason D Robinson, Charles E Green, Gurtej Mann, Vance Rabius, Rosario Wippold, Janice A Blalock, Elie Mouhayar, Jean Tayar, Patrick Chaftari, Paul M Cinciripini
PURPOSE/BACKGROUND: It is unclear whether increasing the dose of varenicline beyond the standard dose of 2 mg/d would improve smoking abstinence. METHODS: We examined the effect of 3 mg/d of varenicline on smoking abstinence among smokers who had reduced their smoking by 50% or more in response to 2 mg/d for at least 6 weeks but had not quit smoking. Of 2833 patients treated with varenicline, dosage of a subset of 73 smokers was increased to 3 mg/d after 6 weeks...
December 11, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29232194/persistent-ventricular-bigeminy-during-anesthesia-in-pediatric-patients-a-case-report-of-an-11-year-old-child
#4
Sheetal Dalal, Vikas Chaudhari
An 11-year-old male child with fractures in both bones in his left forearm presented for open reduction and internal fixation. The pre-anesthetic check-up and investigations did not reveal any pre-existing underlying cardio-respiratory disease. The patient had an uneventful peri-operative period during the operation and was comfortable without any anxiety or restlessness. After an uneventful induction and intubation as per routine protocol, the patient received 600 mg of amoxicillin+clavunate intravenously as an antibiotic...
December 12, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/29231860/predicting-the-functional-impact-of-cdh1-missense-mutations-in-hereditary-diffuse-gastric-cancer
#5
REVIEW
Soraia Melo, Joana Figueiredo, Maria Sofia Fernandes, Margarida Gonçalves, Eurico Morais-de-Sá, João Miguel Sanches, Raquel Seruca
The role of E-cadherin in Hereditary Diffuse Gastric Cancer (HDGC) is unequivocal. Germline alterations in its encoding gene (CDH1) are causative of HDGC and occur in about 40% of patients. Importantly, while in most cases CDH1 alterations result in the complete loss of E-cadherin associated with a well-established clinical impact, in about 20% of cases the mutations are of the missense type. The latter are of particular concern in terms of genetic counselling and clinical management, as the effect of the sequence variants in E-cadherin function is not predictable...
December 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29231747/practice-patterns-to-improve-pre-and-post-transplant-medication-adherence-in-heart-transplant-centres-a-secondary-data-analysis-of-the-international-bright-study
#6
Yuliya Senft, Monika Kirsch, Kris Denhaerynck, Fabienne Dobbels, Remon Helmy, Cynthia L Russell, Lut Berben, Sabina De Geest
BACKGROUND: As medication non-adherence is a major risk factor for poor post-transplant outcomes, we explored how adherence is assessed, enhanced and integrated across the transplant continuum. AIM: The aim of this study was to study practice patterns regarding pre- and post-transplant medication adherence assessment and interventions in international heart transplant centres. METHODS: We used data from the Building Research Initiative Group: chronic illness management and adherence in heart transplantation (BRIGHT) study, a cross-sectional study conducted in 36 heart transplant centres in 11 countries...
December 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29230583/mutation-screening-of-chinese-treacher-collins-syndrome-patients-identified-novel-tcof1-mutations
#7
Ying Chen, Luo Guo, Chen-Long Li, Jing Shan, Hai-Song Xu, Jie-Ying Li, Shan Sun, Shao-Juan Hao, Lei Jin, Gang Chai, Tian-Yu Zhang
Treacher Collins syndrome (TCS) (OMIM 154500) is a rare congenital craniofacial disorder with an autosomal dominant manner of inheritance in most cases. To date, three pathogenic genes (TCOF1, POLR1D and POLR1C) have been identified. In this study, we conducted mutational analysis on Chinese TCS patients to reveal a mutational spectrum of known causative genes and show phenotype-genotype data to provide more information for gene counselling and future studies on the pathogenesis of TCS. Twenty-two TCS patients were recruited from two tertiary referral centres, and Sanger sequencing for the coding exons and exon-intron boundaries of TCOF1, POLR1D and POLR1C was performed...
December 11, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/29230341/pancreatic-laceration-in-a-pediatric-patient-an-unexpected-diagnosis
#8
Michelle J Hong, Lauren M Porter, Debra D Esernio-Jenssen, Andrew C Miller, Marna Rayl Greenberg
Pediatric pancreatic injuries are rare. We present an atypical case that occurred in a 4-year-old male. The child presented with a twenty-four-hour history of vomiting that had progressed to right lower quadrant abdominal pain on examination in the emergency department. The initial differential was gastroenteritis versus appendicitis. An abnormality on the ultrasonography and an elevated lipase level eventually led to an MRI showing a complete transection through the posterior margin of the pancreas. The patient was admitted to pediatric surgery and underwent a successful distal pancreatectomy with preservation of the spleen...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29230163/genetic-counselling-pitfall-co-occurrence-of-an-11-8-mb-xp22-duplication-and-an-xp21-2-duplication-disrupting-il1rapl1
#9
Nicolas Chatron, Lucie Thibault, James Lespinasse, Audrey Labalme, Caroline Schluth-Bolard, Marianne Till, Patrick Edery, Renaud Touraine, Vincent des Portes, Gaetan Lesca, Damien Sanlaville
We report a 3-generation family in which 2 Xp copy number variations (CNVs) co-segregate. The proband presented with syndromic intellectual disability. The CNV had been revealed by conventional karyotyping, identifying a large Xp22 duplication causing an Xp functional disomy. Family studies found that this duplication was inherited from the proband's mother and was also present in one of his sisters. This sister had conventional karyotyping performed during pregnancy with a normal result. Postnatally, her child, the proband's nephew, presented with autism spectrum disorders...
November 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/29228940/communicating-wisely-teaching-residents-to-communicate-effectively-with-patients-and-caregivers-about-unnecessary-tests
#10
Geetha Mukerji, Adina Weinerman, Sarah Schwartz, Adelle Atkinson, Lynfa Stroud, Brian M Wong
BACKGROUND: With rising healthcare costs and a focus on quality, there is a growing need to promote resource stewardship in medical education. Physicians need to be able to communicate effectively with patients/caregivers seeking tests and treatments that are unnecessary. This study aimed to evaluate the impact of an interactive workshop on residents' knowledge of resource stewardship and communication skills when counseling patients/caregivers about requests for unnecessary testing. METHODS: Participants were 83 Internal Medicine and Pediatrics residents at the University of Toronto in 2014-15...
December 11, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29227723/interventions-to-address-sexual-problems-in-people-with-cancer-american-society-of-clinical-oncology-clinical-practice-guideline-adaptation-of-cancer-care-ontario-guideline
#11
Jeanne Carter, Christina Lacchetti, Barbara L Andersen, Debra L Barton, Sage Bolte, Shari Damast, Michael A Diefenbach, Katherine DuHamel, Judith Florendo, Patricia A Ganz, Shari Goldfarb, Sigrun Hallmeyer, David M Kushner, Julia H Rowland
Purpose The adaptation of the Cancer Care Ontario (CCO) guideline Interventions to Address Sexual Problems in People With Cancer provides recommendations to manage sexual function adverse effects that occur as a result of cancer diagnosis and/or treatment. Methods ASCO staff reviewed the guideline for developmental rigor and updated the literature search. An ASCO Expert Panel ( Table A1 ) was assembled to review the guideline content and recommendations. Results The ASCO Expert Panel determined that the recommendations from the 2016 CCO guideline are clear, thorough, and based upon the most relevant scientific evidence...
December 11, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29227718/training-chiropractic-students-in-weight-management-counseling-using-standardized-patients
#12
Cheryl Hawk, Michael Ramcharan, Carla LeRiche Kruger
OBJECTIVE: The aim of this study was to describe and assess an activity that trained chiropractic students to counsel patients on weight management through the use of standardized patients. METHODS: This was a descriptive study using mixed methods. Students were trained to apply health behavior theory and the transtheoretical model. Standardized patients were given a case to portray with the students. Students had 15 minutes for the encounter. The encounters were assessed in 2 ways: (1) standardized patients answered a brief questionnaire about the students' performance, and (2) students answered a questionnaire about the utility of the intervention...
December 11, 2017: Journal of Chiropractic Education
https://www.readbyqxmd.com/read/29227577/management-of-pain-in-end-stage-renal-disease-patients-short-review
#13
REVIEW
Rupesh Raina, Vinod Krishnappa, Mona Gupta
Pain management in end stage renal disease (ESRD) patients is a complex and challenging task to accomplish, and effective pain and symptom control improves quality of life. Pain is prevalent in more than 50% of hemodialysis patients and up to 75% of these patients are treated ineffectively due to its poor recognition by providers. A good history for PQRST factors and intensity assessment using visual analog scale are the initial steps in the management of pain followed by involvement of palliative care, patient and family counseling, discussion of treatment options, and correction of reversible causes...
December 11, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29227445/mobile-hearing-testing-applications-and-the-diagnosis-of-sudden-sensorineural-hearing-loss-a-cautionary-tale
#14
Rosh K V Sethi, Iman Ghanad, Vivek Kanumuri, Barbara Herrmann, Elliott D Kozin, Aaron K Remenschneider
OBJECTIVE: Mobile hearing applications (apps) are available for hearing testing, personal sound amplification, as well as hearing aid modulation. Hearing testing apps are gaining popularity, especially in resource-limited settings. The reliability of mobile hearing testing apps, however, is not well characterized. PATIENTS/INTERVENTIONS: A case study of a single patient with a complaint of sudden hearing loss presenting to a tertiary-care hospital. MAIN OUTCOME MEASURE: Comparison of a mobile hearing testing app results with standard audiogram...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29226997/participation-and-interest-in-support-services-among-family-caregivers-of-older-adults-with-cancer
#15
J Nicholas Dionne-Odom, Allison J Applebaum, Katherine Ornstein, Andres Azuero, Paula P Warren, Richard A Taylor, Gabrielle Rocque, Elizabeth Kvale, Wendy Demark-Wahnefried, Maria Pisu, Edward Partridge, Michelle Y Martin, Marie Bakitas
OBJECTIVE: To describe distressed and underprepared family caregiver's use of and interest in formal support services (e.g., professional counseling, education, organizational assistance). METHODS: Cross-sectional mail survey conducted in communities of eight cancer centers in Tennessee, Alabama, and Florida (response rate: 42%). Family caregivers of Medicare beneficiaries with pancreatic, lung, brain, ovarian, head and neck, hematologic, and stage IV cancers reported support service use and completed validated measures of depression, anxiety, burden, preparedness, and health...
December 11, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29226869/the-heritability-of-frontotemporal-lobar-degeneration-validation-of-pedigree-classification-criteria-in-a-northern-italy-cohort
#16
Silvia Fostinelli, Miriam Ciani, Roberta Zanardini, Orazio Zanetti, Giuliano Binetti, Roberta Ghidoni, Luisa Benussi
A large portion of frontotemporal lobar degeneration (FTLD) patients has a family history of disease and the presence of a pathogenic mutation confirms the clinical diagnosis. Recently, standardized criteria to evaluate FTLD pedigree, based on first- and second-degree affected relatives, their age at onset, and clinical phenotype, were proposed and validated in an American cohort. Herein we applied these criteria to 402 Italian FTLD pedigrees and assessed mutation frequencies in GRN, C9orf72, and MAPT genes with the aim of validating these criteria...
December 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29226694/effectiveness-of-motivational-interviewing-for-improving-physical-activity-self-management-for-adults-with-type-2-diabetes-a-review
#17
Patricia Davern Soderlund
Objectives This review examines the effectiveness of motivational interviewing for physical activity self-management for adults diagnosed with diabetes mellitus type 2. Motivational interviewing is a patient centered individually tailored counseling intervention that aims to elicit a patient's own motivation for health behavior change. Review questions include (a) How have motivational interviewing methods been applied to physical activity interventions for adults with diabetes mellitus type 2? (b) What motivational interviewing approaches are associated with successful physical activity outcomes with diabetes mellitus 2? Methods Database searches used PubMed, CINAHL, and PsycINFO for the years 2000 to 2016...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/29226236/self-assessment-of-competence-during-post-graduate-training-in-general-medicine-a-preliminary-study-to-develop-a-portfolio-for-further-education
#18
Bert Huenges, Barbara Woestmann, Susanne Ruff-Dietrich, Herbert Rusche
Awareness of one's own strengths and weaknesses is a key qualification for the specialist physician. We examined how physicians undergoing specialist training in general medicine rate themselves in different areas. For this purpose, 139 participants receiving post-graduate training in general practice offered by the Medical Association of Westfalen-Lippe assessed themselves regarding their subjective confidence in 20 core competencies and 47 situations involving patient counseling in general practice. Their self-assessments were recorded on a five-point Likert scale...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29225794/premature-ovarian-insufficiency-an-update-on-recent-advances-in-understanding-and-management
#19
REVIEW
Saioa Torrealday, Pinar Kodaman, Lubna Pal
Premature ovarian insufficiency is a complex and relatively poorly understood entity with a myriad of etiologies and multisystem sequelae that stem from premature deprivation of ovarian sex hormones. Timely diagnosis with a clear understanding of the various comorbidities that can arise from estrogen deficiency is vital to appropriately counsel and treat these patients. Prompt initiation of hormone therapy is critical to control the unsolicited menopausal symptoms that many women experience and to prevent long-term health complications...
2017: F1000Research
https://www.readbyqxmd.com/read/29225788/whole-exome-sequencing-for-detecting-inborn-errors-of-immunity-overview-and-perspectives
#20
REVIEW
Barbara Bosch, Yuval Itan, Isabelle Meyts
The study of inborn errors of immunity is based on a comprehensive clinical description of the patient's phenotype and the elucidation of the underlying molecular mechanisms and their genetic etiology. Deciphering the pathogenesis is key to genetic counseling and the development of targeted therapy. This review shows the power of whole-exome sequencing in detecting inborn errors of immunity along five central steps taken in whole-exome sequencing analysis. In parallel, we highlight the challenges for the clinical and scientific use of the method and how these hurdles are currently being addressed...
2017: F1000Research
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