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https://www.readbyqxmd.com/read/29929187/one-year-results-for-patients-with-unilateral-hearing-loss-and-accompanying-severe-tinnitus-and-hyperacusis-treated-with-a-cochlear-implant
#1
Angel Ramos Macías, Juan Carlos Falcón-González, Manuel Manrique Rodríguez, Constantino Morera Pérez, Luis García-Ibáñez, Carlos Cenjor Español, Chrystelle Coudert-Koall, Matthijs Killian
OBJECTIVE: To show that patients with unilateral hearing loss (UHL), with one ear fulfilling cochlear implant (CI) indication criteria, and an additional severe tinnitus handicap can be treated effectively with a CI. METHOD: A prospective multi-centre study was conducted in five Spanish centres. Sixteen adult patients with UHL and a mean Tinnitus Handicap Inventory (THI) score of at least 58 were implanted. The study design included repeated within-subject measures of quality of life (Health Utility Index Mark 3 [HUI3]), tinnitus (THI, Visual Analogue Scale [VAS] on tinnitus loudness), hearing (Speech, Spatial, and Qualities of Hearing Scale- [SSQ]), and hyperacusis (Test de Hipersensibilidad al Sonido [THS]) up to 12 months after the initial CI fitting...
June 21, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29928638/improvements-in-high-resolution-laryngeal-magnetic-resonance-imaging-for-preoperative-transoral-laser-microsurgery-and-radiotherapy-considerations-in-early-lesions
#2
Thomas Ruytenberg, Berit M Verbist, Jordi Vonk-Van Oosten, Eleftheria Astreinidou, Elisabeth V Sjögren, Andrew G Webb
As the benefits, limitations, and contraindications of transoral laser microsurgery (TLM) in glottic carcinoma treatments become better defined, pretreatment imaging has become more important to assess the case-specific suitability of TLM and to predict functional outcomes both for treatment consideration and patient counseling. Magnetic resonance imaging (MRI) is the preferred modality to image such laryngeal tumors, even though imaging the larynx using MRI can be difficult. The first challenge is that there are no commercial radiofrequency (RF) coils that are specifically designed for imaging the larynx, and performance in terms of coverage and signal-to-noise ratio is compromised using general-purpose RF coils...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29928182/a-novel-mgp-gene-mutation-causing-keutel-syndrome-in-a-brazilian-patient
#3
Eduardo Perrone, Kelin Chen, Marco Ramos, Maria Fernanda Milanezi, Viviane Nakano, Ariane Falconi, Juliana Silva, Jamille Campos, Celia M C Silva, Joao B O Filho, Ana B A Perez
Keutel syndrome is caused by mutations in the matrix gamma-carboxyglutamic acid ( MGP ) gene (OMIM 154870) and is inherited in an autosomal recessive fashion. It is characterized by brachydactyly, pulmonary artery stenosis, a distinctive facial phenotype, and cartilage calcification. To date, only 36 cases have been reported worldwide. We describe clinical and molecular findings of the first Brazilian patient with Keutel syndrome. Keutel syndrome was suspected based on clinical and morphological evaluation, so we sequenced the MGP gene using the TruSight One Sequencing Panel (Illumina)...
May 2018: Molecular Syndromology
https://www.readbyqxmd.com/read/29927817/the-human-papilloma-vaccine-a-time-for-np-leadership
#4
Robin L Hardwicke, Laura J Benjamins, Richard M Grimes
The human papilloma virus (HPV) causes approximately 30,700 annual cancer cases of the cervix, vulva, vagina, penis, oral cavity, and anus. Nurse practitioners can use their unique relationships with patients to advocate for the HPV vaccine. The purpose of this article is to update NPs on current knowledge regarding the HPV vaccine while providing appropriate information necessary for counseling patients and parents.
July 2018: Nurse Practitioner
https://www.readbyqxmd.com/read/29927641/disparities-in-smoking-cessation-assistance-in-us-primary-care-clinics
#5
Steffani R Bailey, John Heintzman, R Lorie Jacob, Jon Puro, Miguel Marino
OBJECTIVES: To examine associations between patient factors and smoking cessation assistance in US safety-net clinics. METHODS: Using electronic health record data from the OCHIN network, we identified adults with at least 1 primary care visit to a study clinic (n = 143 clinics in 12 states) with at least 1 documented "current smoker" status during 2014 to 2016 (n = 136 314; 29.8%). We estimated odds ratios (ORs) of smoking cessation assistance receipt (none [reference], counseling, medication, or both) by patient covariates...
June 21, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29926740/the-role-of-social-media-and-internet-search-engines-in-information-provision-and-dissemination-to-patients-with-kidney-stone-disease-ksd-a-systematic-review-from-eau-young-academic-urologists-yau
#6
Enakshee Jamnadass, Omar Aboumarzouk, Panagiotis Kallidonis, Esteban Emiliani, Thomas Tailly, Stephan Hruby, Francesco Sanguedolce, Gokhan Atis, Mehmet Özsoy, Francesco Greco, Bhaskar K Somani
INTRODUCTION: Kidney stone disease (KSD) affects millions of people worldwide and has an increasing incidence. Social media (SoMe) and search engines are both gaining in usage, whilst also being used by patients to research their conditions and aid in managing them. With this in mind, many authors have expressed the belief that SoMe and search engines can be used by patients and healthcare professionals to improve treatment compliance, and to help counselling and management of conditions such as KSD...
June 21, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29926365/changes-in-ocular-surface-status-after-phacoemulsification-in-patients-with-senile-cataract
#7
Piyush Kohli, Sudesh Kumar Arya, Amit Raj, Uma Handa
AIM: To evaluate the signs and symptoms of dry eye after phacoemulsification; effects on the status of ocular surface using impression cytology; and associated risk factors. METHODS: Prospective study included 50 eyes (50 patients) with no dry eye signs or symptoms, who underwent clear corneal phacoemulsification for senile cataract. Dry eye indices used included Ocular Surface Disease Index scoring, Schirmer I test, tear break up time, tear meniscus height, corneal fluorescein staining, lissamine green staining and goblet cell density (GCD) with the help of impression cytology...
June 20, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29925252/potential-role-of-the-gut-microbiome-in-als-a-systematic-review
#8
Michelle L Wright, Christina Fournier, Madelyn C Houser, Malú Tansey, Jonathan Glass, Vicki Stover Hertzberg
Amyotrophic lateral sclerosis (ALS) etiology and pathophysiology are not well understood. Recent data suggest that dysbiosis of gut microbiota may contribute to ALS etiology and progression. This review aims to explore evidence of associations between gut microbiota and ALS etiology and pathophysiology. Databases were searched for publications relevant to the gut microbiome in ALS. Three publications provided primary evidence of changes in microbiome profiles in ALS. An ALS mouse model revealed damaged tight junction structure and increased permeability in the intestine versus controls along with a shifted microbiome profile, including decreased levels of butyrate-producing bacteria...
January 1, 2018: Biological Research for Nursing
https://www.readbyqxmd.com/read/29924808/genomic-information-and-a-person-s-right-not-to-know-a-closer-look-at-variations-in-hypothetical-informational-preferences-in-a-german-sample
#9
Laura Flatau, Markus Reitt, Gunnar Duttge, Christian Lenk, Barbara Zoll, Wolfgang Poser, Alexandra Weber, Urs Heilbronner, Marcella Rietschel, Jana Strohmaier, Rebekka Kesberg, Jonas Nagel, Thomas G Schulze
In clinical practice and in research, there is an ongoing debate on how to return incidental and secondary findings of genetic tests to patients and research participants. Previous investigations have found that most of the people most of the time are in favor of full disclosure of results. Yet, the option to reject disclosure, based on the so-called right not to know, can be valuable especially for some vulnerable subgroups of recipients. In the present study we investigated variations in informational preferences in the context of genetic testing in a large and diverse German sample...
2018: PloS One
https://www.readbyqxmd.com/read/29924764/complications-after-superficial-parotidectomy-for-pleomorphic-adenoma
#10
P Infante-Cossio, E Gonzalez-Cardero, A Garcia-Perla-Garcia, E Montes-Latorre, J-L Gutierrez-Perez, E Prats-Golczer
BACKGROUND: The significance of complications after superficial parotidectomy remains unclear, since prospective studies are lacking. The aim of this study was to evaluate facial nerve dysfunction and other postoperative complications after superficial parotidectomy for pleomorphic adenoma of the superficial lobe and to identify the associated risk factors. MATERIAL AND METHODS: Prospective and descriptive clinical study on 79 patients undergoing formal superficial parotidectomy with the modified facelift incision, dissection of the facial nerve and reconstruction with the superficial musculoaponeurotic system flap...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29924011/clinical-inertia-in-the-pharmacological-management-of-hypertension-a-systematic-review-and-meta-analysis
#11
Tal Milman, Raed A Joundi, Naif M Alotaibi, Gustavo Saposnik
BACKGROUND: Clinical Inertia is defined as "failure of health care providers to initiate or intensify therapy according to current guidelines". This phenomenon is gaining increasing attention as a major cause of clinicians' failure to adequately manage hypertension, thus leading to an increased incidence of cardiovascular events. We performed a systematic review and meta-analysis of randomized controlled trials to determine whether interventions aimed at reducing clinical inertia in the pharmacological treatment of hypertension improve blood pressure (BP) control...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923533/diabetes-self-care-activities-among-adults-20-years-and-above-residing-in-a-resettlement-colony-in-east-delhi
#12
Anu Mohandas, S K Bhasin, Madhu Upadhyay, S V Madhu
Background: Self-care activities are the cornerstone of diabetes care that ensures patients participation to achieve optimal glycemic control and to prevent complications. Objective: The aim of this study is to find the level of self-care activities among diabetics aged ≥20 years residing in a resettlement colony in East Delhi and its association with sociodemographic factors, disease, and treatment profile. Methods: Using cross-sectional survey, 168 known diabetic patients were selected from Nand Nagri, a resettlement colony in East Delhi...
April 2018: Indian Journal of Public Health
https://www.readbyqxmd.com/read/29923115/finding-a-balance-reconciling-the-needs-of-the-institution-patient-and-genetic-counselor-for-optimal-resource-utilization
#13
Devanshi Patel, Erica L Blouch, Linda H Rodgers-Fouché, Margaret M Emmet, Kristen M Shannon
The current practice of cancer genetic counseling is undergoing widespread change and scrutiny. While there are clinical resources for genetic counselors (GCs) regarding the delivery of cancer genetic services, there is limited literature regarding effective management of a genetic counseling clinical program. We have developed administrative tools to manage a large team of GCs at a single academic medical center over a period of increasing demand for genetics services, with the initial aim of decreasing wait time for urgent genetic counseling visits...
June 19, 2018: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29922900/the-economic-burden-of-disease-of-epithelial-ovarian-cancer-in-spain-the-ovarcost-study
#14
Laura Delgado-Ortega, Almudena González-Domínguez, Josep María Borrás, Juan Oliva-Moreno, Eva González-Haba, Salomón Menjón, Pedro Pérez, David Vicente, Luis Cordero, Margarita Jiménez, Susana Simón, Álvaro Hidalgo-Vega, Carlota Moya-Alarcón
OBJECTIVE: To assess the economic burden of epithelial ovarian cancer (EOC) in incident patients and the burden by disease stage in Spain. METHODS: We developed a Markov model from a social perspective simulating the natural history of EOC and its four stages, with a 10-year time horizon, 3-week cycles, 3% discount rate, and 2016 euros. Healthcare resource utilization and costs were estimated by disease stage. Direct healthcare costs (DHC) included early screening, genetic counselling, medical visits, diagnostic tests, surgery, chemotherapy, hospitalizations, emergency services, and palliative care...
June 19, 2018: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29922098/exploring-the-effectiveness-of-crisis-counseling-and-psychoeducation-in-relation-to-improving-mental-well-being-quality-of-life-and-treatment-compliance-of-breast-cancer-patients-in-qatar
#15
Reem Jawad Al-Sulaiman, Abdulbari Bener, Lisa Doodson, Salha Bujassoum Al Bader, Suhaila Ghuloum, Alain Lemaux, Hekmat Bugrein, Reena Alassam, Aisha Karim
Background: An insufficient number of studies have been carried out in the Middle East to evaluate the role of structured psychotherapeutic interventions in enhancing breast cancer patients' psychological well-being, quality of life and treatment compliance. This study has been designed to address this limitation by exploring the benefit of two structured psychotherapeutic interventions, crisis counseling and psychoeducation, in enhancing breast cancer patients' psychological well-being, quality of life and treatment compliance in Qatar...
2018: International Journal of Women's Health
https://www.readbyqxmd.com/read/29921875/a-faroese-founder-variant-in-tbcd-causes-early-onset-progressive-encephalopathy-with-a-homogenous-clinical-course
#16
Sabine Grønborg, Lotte Risom, Jakob Ek, Karen Bonde Larsen, David Scheie, Yanko Petkov, Vibeke André Larsen, Morten Dunø, Fróði Joensen, Elsebet Østergaard
An intact and dynamic microtubule cytoskeleton is crucial for the development, differentiation, and maintenance of the mammalian cortex. Variants in a host of structural microtubulin-associated proteins have been identified to cause a wide spectrum of malformations of cortical development and alterations of microtubule dynamics have been recognized to cause or contribute to progressive neurodegenerative disorders. TBCD is one of the five tubulin-specific chaperones and is required for reversible assembly of the α-/β-tubulin heterodimer...
June 19, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29921432/no-361-caesarean-delivery-on-maternal-request
#17
Eman Alsayegh, Hayley Bos, Kim Campbell, Jon Barrett
A maternal request for an elective CS in the absence of a maternal or fetal indication may raise risk-benefit considerations and ethical concerns for a health care provider. Appropriate counselling of the patient on the risks and benefits in proceeding with a CDMR without medical indication is essential. Providers should have a clear knowledge of the risks and benefits of providing an elective CS without medical indications compared to the risks and benefits of supporting an attempt at vaginal delivery, so that the patient may reach an informed decision...
July 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29921429/water-related-vaginal-injury-a-case-report-and-review-of-the-literature
#18
Isabelle Gauthier, Aisling A Clancy, Jennifer Lipson, Dante Pascali
BACKGROUND: Vaginal injury can result from entry of water into the vagina under high pressure. Previously reported cases describe water-jet vaginal injuries in women participating in water-related activities, including: water skiing, personal watercraft use, waterslides, water hose and fountains, with and without foreign body in situ. CASE: We describe the case of a severe vaginal laceration and hemorrhage in a 44-year-old female from a high-pressure water-jet generated during a water-ski fall requiring operative repair...
July 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29920910/fertility-managment-in-testicular-cancer-the-need-for-establishing-a-standardised-and-evidenced-based-patient-centric-pathway
#19
REVIEW
Jemma A Moody, Kamran Ahmed, Tet Yap, Suks Minhas, Majid Shabbir
OBJECTIVES: To determine the impact of testicular cancer and its treatments on fertility and to review the current management options for the infertile, testicular cancer patient, both before diagnosis and after treatment, with the aim to provide practical recommendations to update contemporary guidelines and standardise clinical practice. PATIENTS AND METHODS: Searches for relevant articles on Pubmed and Google Scholar between 2000-2017, with additional articles sourced from reference lists of included publications...
June 19, 2018: BJU International
https://www.readbyqxmd.com/read/29920429/changes-in-sexuality-during-ulipristal-acetate-treatment-in-women-with-symptomatic-uterine-fibroids
#20
Benjamin Tuschy, Mirja Gabbert, Christel Weiss, Amadeus Hornemann, Anne Wuhrer, Marc Sütterlin, Sebastian Berlit
OBJECTIVE: To evaluate changes in sexuality in women treated with Ulipristal acetate (UPA) due to symptomatic uterine fibroids. STUDY DESIGN: A total of 102 women with symptomatic uterine fibroids undergoing conservative therapy with UPA were enrolled in this observational study. Sexuality was evaluated before and after a three month UPA treatment using the Female Sexual Functioning Index (FSFI) as well as the Sexual Activity Questionnaire (SAQ). Before treatment was initiated, participants additionally filled in a standardised questionnaire addressing the expected changes in sexuality due to UPA...
June 16, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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