keyword
https://read.qxmd.com/read/38652310/predictors-of-significant-distress-in-cervical-cancer-patients-a-cross-sectional-study
#1
JOURNAL ARTICLE
Friederike Schmitt, Laila Najjari, Tomas Kupec, Elmar Stickeler, Ivo Meinhold-Heerlein, Julia Wittenborn
PURPOSE: This cross-sectional study aims to investigate parameters that predict relevant levels of distress in women in a perioperative setting undergoing treatment for cervical cancer. MATERIALS AND METHODS: Data from 495 patients with cervical cancer that were treated at the university hospital Aachen between 2010 and 2022 were analysed based on their respective National Comprehensive Cancer Network (NCCN) Distress Thermometer score (DT) and Problem List (PL) and their clinical history...
April 23, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38652248/genetic-aortopathies-a-case-based-approach-to-multidisciplinary-program-development
#2
JOURNAL ARTICLE
Christopher P Jordan, Akos Berthold, Jason Bonomo
PURPOSE OF REVIEW: The incorporation of genetic counseling and testing is essential to evaluation and management of thoracic aortic disease in patients under 60 years of age and those with family histories suspicious for heritable thoracic aortic disease and disorders associated with increased risk for acute type-A aortic dissection. RECENT FINDINGS: As many as 20% of individuals with thoracic aortic disease under the age of 60 years have autosomal dominant patterns of inheritance...
April 22, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38651539/length-of-stay-prediction-models-for-oral-cancer-surgery-machine-learning-statistical-and-acs-nsqip
#3
JOURNAL ARTICLE
Amirpouyan Namavarian, Alexander Gabinet-Equihua, Yangqing Deng, Shuja Khalid, Hedyeh Ziai, Konrado Deutsch, Jingyue Huang, Ralph W Gilbert, David P Goldstein, Christopher M K L Yao, Jonathan C Irish, Danny J Enepekides, Kevin M Higgins, Frank Rudzicz, Antoine Eskander, Wei Xu, John R de Almeida
OBJECTIVE: Accurate prediction of hospital length of stay (LOS) following surgical management of oral cavity cancer (OCC) may be associated with improved patient counseling, hospital resource utilization and cost. The objective of this study was to compare the performance of statistical models, a machine learning (ML) model, and The American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) calculator in predicting LOS following surgery for OCC. MATERIALS AND METHODS: A retrospective multicenter database study was performed at two major academic head and neck cancer centers...
April 23, 2024: Laryngoscope
https://read.qxmd.com/read/38651529/pathogenic-gene-variants-identified-in-patients-presenting-with-perthes-or-perthes-like-hip-disorder
#4
JOURNAL ARTICLE
Gabrielle Marchelli, Candelaria Mercado, Corey S Gill, Harry K W Kim
AIMS: Legg-Calve-Perthes disease (LCPD) is a diagnosis of exclusion. Various conditions, such as skeletal dysplasias, can closely mimic LCPD and these must be ruled out to provide appropriate treatment, prognosis, and counseling. Traditionally, genetic testing has not been readily available in pediatric orthopaedic practice. Furthermore, the clinical value of genetic testing patients with LCPD is unclear. With the advance of next-generation sequencing (NGS) technology, genetic testing has become clinically available as a lab test...
April 23, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38651447/screw-diameter-and-use-of-a-washer-affect-symptomatic-implant-removal-rates-in-pediatric-medial-epicondyle-fractures
#5
JOURNAL ARTICLE
Matthew J Siebert, Emily Zhang, Senah E Stephens, Aaron J Wey, Kaleb Eppich, Angela P Presson, Stephanie M Holmes, Christopher A Makarewich
OBJECTIVE: Medial epicondyle fractures are a common pediatric injury. When operative, cannulated partially threaded screws, with or without a washer, are commonly utilized. These implants may need to be removed after full healing if symptomatic. There is mixed evidence regarding the influence of a washer on rates of implant removal, and the influence of screw size has not been studied. We aim to determine the rate of symptomatic deep implant removal for each fixation type and identify factors associated with the need for removal...
April 23, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38651210/comparison-of-the-performance-of-nipt-and-nipt-plus-for-fetal-chromosomal-aneuploidy-and-high-z-score-increases-the-positive-predictive-value
#6
JOURNAL ARTICLE
Siping Liu, Yushuang Xu, Qingxian Chang, Bei Jia, Fenxia Li
OBJECTIVE: To evaluate non-invasive prenatal testing (NIPT) and expanded non-invasive prenatal testing (NIPT-plus) for detecting aneuploidies at different sequencing depths and assess Z-score accuracy in predicting trisomies 21, 18, 13, 45X, and 47XXX. METHODS: Pregnancies with positive NIPT or NIPT-plus results detected at the prenatal diagnosis center of Nanfang Hospital were included in this retrospective study, between January 2017 and December 2022. Invasive prenatal diagnostic results were collected...
April 23, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38650784/breaking-bad-news-during-prenatal-screening-the-role-of-professional-obstetricians-and-midwives-in-greece
#7
Anna Glynou, Dionysios G Galatis, Vassilis Yalelis, Alexandros Sotiriadis, Andreas Pampanos, Angeliki Sarella, Eirini Chasalevri, Maria Koukaki, Panagiotis M Peitsidis, Makarios Eleftheriades
INTRODUCTION: Breaking bad news is one of the most difficult responsibilities in medical practice. Although medical staff in clinical practice often encounter situations that necessitate the announcement of unpleasant news, there is a lack of training regarding their communication with patients and their families. Effective interaction between medical staff and pregnant women constitutes a crucial component of breaking down unpleasant news. This research aimed to investigate the knowledge and attitude of health professionals, particularly obstetricians, and midwives, regarding the announcement of bad news during prenatal screening...
March 2024: Curēus
https://read.qxmd.com/read/38650723/predicting-anxiety-depression-and-insomnia-among-bangladeshi-university-students-using-tree-based-machine-learning-models
#8
JOURNAL ARTICLE
Arman Hossain Chowdhury, Dana Rad, Md Siddikur Rahman
BACKGROUND AND AIMS: Mental health problem is a rising public health concern. People of all ages, specially Bangladeshi university students, are more affected by this burden. Thus, the objective of the study was to use tree-based machine learning (ML) models to identify major risk factors and predict anxiety, depression, and insomnia in university students. METHODS: A social media-based cross-sectional survey was employed for data collection. We used Generalized Anxiety Disorder (GAD-7), Patient Health Questionnaire (PHQ-9) and Insomnia Severity Index (ISI-7) scale for measuring students' anxiety, depression and insomnia problems...
April 2024: Health Science Reports
https://read.qxmd.com/read/38649066/chronic-oral-corticoteroid-use-and-10-year-incidence-of-major-complications-following-total-knee-arthroplasty
#9
JOURNAL ARTICLE
Mark Haft, Sanjay Kubsad, John M Pirtle, Amil R Agarwal, Rachel Ranson, Thomas Fraychineaud, James DeBritz, Savyasachi C Thakkar, Gregory J Golladay
INTRODUCTION: Oral corticosteroids are the primary treatment for several autoimmune conditions. The risk of long-term implant, bone health, and infectious-related complications in patients taking chronic oral corticosteroids before total knee arthroplasty (TKA) is unknown. We compared the 10-year cumulative incidence of revision, periprosthetic joint infection (PJI), fragility fracture (FF), and periprosthetic fracture (PPF) following TKA in patients who had and did not have preoperative chronic oral corticosteroid use...
April 20, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38648897/outcome-of-prelabor-rupture-of-membranes-before-or-at-the-limit-of-viability-systematic-review-and-meta-analysis
#10
REVIEW
Sara Sorrenti, Daniele DI Mascio, Asma Khalil, Francesco D'Antonio, Giuseppe Rizzo, Fabrizio Zullo, Elena D'Alberti, Valentina D'Ambrosio, Ilenia Mappa, Ludovico Muzii, Antonella Giancotti
BACKGROUND: Counselling of pregnancies complicated by pre- and periviable PROM to reach a shared decision-making is challenging and the current, limited evidence hampers the robustness of the information provided. OBJECTIVE: To elucidate the rate of obstetric and neonatal outcomes following expectant management for premature rupture of membranes (PROM) occurred before or at the limit of viability. STUDY DESIGN: Medline, Embase, Cinahl and Web of Science databases were searched electronically up to September 2023...
April 20, 2024: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38648830/audiometry-interpretation-for-hearing-loss-in-adults
#11
JOURNAL ARTICLE
Mandi Sehgal, Alexandra Sellers, Wendy S Biggs
Hearing loss is a prevalent, chronic condition in the United States; it is often gradual and progressive and is underreported by patients and undertreated by physicians. The impaired ability to effectively hear and communicate may result in negative emotional, cognitive, economic, and social consequences for individuals and may pose a safety risk. Questionnaires and smartphone apps are available to help identify and evaluate self-perceived hearing loss. Physicians should assess for objective hearing impairment when the patient or family member raises a concern or if cognitive or mood symptoms are present that could be influenced by hearing loss...
April 2024: American Family Physician
https://read.qxmd.com/read/38648392/natural-history-of-opioid-use-in-naive-and-tolerant-patients-in-revision-total-hip-arthroplasty
#12
JOURNAL ARTICLE
Zachary C Lum, Daniel T O'Connor, Christopher T Holland, Arta Gharib-Parsa, Analucia Barragan-Trejo, Jeannie Y Park, Mauro Giordani, John P Meehan
BACKGROUND: Opioid use after revision total hip arthroplasty (rTHA) has not been well characterized. The purpose of this study was to characterize preoperative, perioperative, and postoperative opioid use during rTHA. METHODS: Patients undergoing revision THA from 2010 to 2018 were screened for opioid use 3 months before revision surgery and tracked 24 months postoperatively. Patients were categorized as naïve or tolerant. Opioid prescriptions and average morphine milligram equivalents (MME) were compared between the two groups...
April 1, 2024: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/38648372/pre-exposure-prophylaxis-and-telemedicine-during-coronavirus-covid-19-a-qualitative-study-of-the-experiences-of-health-care-professionals-in-mexico
#13
JOURNAL ARTICLE
A Cruz-Bañares, A Rojas-Carmona, S Aguilera-Mijares, A Martínez-Dávalos, S Bautista-Arredondo, H Vermandere
Background Telemedicine, which involves utilising technologies for remote health care delivery, proved useful to continue offering certain health services during the coronavirus disease 2019 (COVID-19) lockdown. However, the extent of its effectiveness in delivering pre-exposure prophylaxis services for HIV prevention remains underexplored from the viewpoint of health care providers. Therefore, this study aimed to assess the experiences of health care professionals in Mexico who utilised telemedicine for delivering pre-exposure prophylaxis services during the COVID-19 contingency...
April 2024: Sexual Health
https://read.qxmd.com/read/38648169/nutrition-macronutrients
#14
JOURNAL ARTICLE
Cynthia Cheng, Erin England
Macronutrients are nutrients the body needs in large quantities, such as fats, carbohydrates, fiber, protein, and water. The exact quantity of macronutrients needed for an individual depends on multiple factors such as height, weight, sex, physical activity level, and medical conditions. For adequate intake, the Dietary Guidelines for Americans, 2020-2025 ( DGA ) recommend an overall healthy eating pattern rather than specific macronutrient amounts. A healthy eating pattern includes consumption of minimally processed, nutrient-dense foods and beverages such as vegetables, fruits, grains, dairy, proteins, and oils...
April 2024: FP Essentials
https://read.qxmd.com/read/38648048/a-mimicker-of-differentiated-vulvar-intraepithelial-neoplasia-reactive-atypia-from-noncompliance-with-lichen-sclerosus-therapy
#15
JOURNAL ARTICLE
Advaita S Chaudhari, Jason R McFadden, Jessica Bentz, Rebecca H Evans, Maria A Selim, Aravindhan Sriharan
Differentiated vulvar intraepithelial neoplasia (d-VIN) is an HPV-independent precursor to vulvar squamous cell carcinoma. The histology of d-VIN lesions is difficult to differentiate from that of non-neoplastic epithelial disorders, especially lichen sclerosus (LS). The authors present a case of LS, where relying on histopathology alone could have led to misdiagnosis. The patient was a 17-year-old female patient with clinical features of vulvar dermatitis and LS for 2 years. She was counseled to apply clobetasol 0...
April 23, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38647243/opt-out-syphilis-screening-at-an-urgent-care-center-in-atlanta-evaluation-of-a-pilot-program
#16
JOURNAL ARTICLE
Stephanie Sweitzer, Joseph Sharp, Dylan Baker, Alexis Lynch, Meredith A Stauch, Matthew Wheatley, Meredith Lora, Valeria D Cantos, Judah Gruen
BACKGROUND: HIV and syphilis disproportionately impact communities with low access to primary care, who often utilize urgent care centers (UCC) for sexual healthcare. UCC visits represent an opportunity for identification and treatment of syphilis and linkage to HIV testing and prevention services. We describe a universal, opt-out syphilis screening program pilot at an Atlanta UCC. METHODS: A chart review was performed on patients 18 years and older who were offered opt-out syphilis screening and had a rapid plasma reagin (RPR) test collected from 9/1/21 to 12/31/21...
April 19, 2024: Sexually Transmitted Diseases
https://read.qxmd.com/read/38646388/comparative-efficacy-of-non-invasive-therapies-in-temporomandibular-joint-dysfunction-a-systematic-review
#17
REVIEW
Hesham A Alowaimer, Sultan S Al Shutwi, Mohammed K Alsaegh, Ohood M Alruwaili, Abdullah R Alrashed, Salwa H AlQahtani, Mohammed S Batais
Temporomandibular disorder (TMD) is a multifaceted disorder impacting the temporomandibular joint (TMJ), causing substantial discomfort and functional limitations. This systematic review aims to comprehensively assess the effectiveness of non-invasive treatment modalities for TMJ dysfunction, prioritizing a definitive protocol to ensure patient safety and enhance quality of life. Employing the PRISMA guidelines, we meticulously analyzed 20 studies from a pool of 1,417 articles sourced from databases such as PubMed, Google Scholar, ScienceDirect, and Medline...
March 2024: Curēus
https://read.qxmd.com/read/38646199/dry-socket-prevalence-and-risk-factors-in-third-molar-extractions-a-prospective-observational-study
#18
JOURNAL ARTICLE
Parul Tandon, Sushil Kumar Sahoo, Liza Mohanty, Nupur Jain, Vidya Hittalamani, Swapnali Shinde Kamble, Ramanpal Singh
Background Third molar extraction is a routine oral surgical procedure that is often complicated by the development of a dry socket (alveolar osteitis). This prospective observational study aimed to investigate the prevalence of dry sockets and identify associated risk factors and causes, contributing to a comprehensive understanding of the postoperative outcomes of oral surgery. Methods This study employed a prospective observational design with a 12-month follow-up period. Participants aged 18-40 years scheduled for third molar extraction were included, whereas those with coagulopathies, pregnant or lactating women, patients with vitamin deficiencies, and individuals on medications affecting healing were excluded...
March 2024: Curēus
https://read.qxmd.com/read/38645811/regional-versus-general-anaesthesia-in-percutaneous-nephrolithotomy-a-systematic-review-and-meta-analysis
#19
REVIEW
Mohammed Shahait, Tuan Thanh Nguyen, Nguyen Xuong Duong, Philip Mucksavage, Bhaskar K Somani
INTRODUCTION: Several studies have compared the safety and effectiveness of general and regional anaesthesia in percutaneous nephrolithotomy (PCNL). This study aimed to compare the perioperative and postoperative outcomes of general anaesthesia and regional anaesthesia for patients undergoing PCNL. MATERIAL AND METHODS: For relevant articles, three electronic databases, including PubMed, Scopus, and Web of Science, were searched from their inception until March 2023...
2024: Central European Journal of Urology
https://read.qxmd.com/read/38645305/clinical-prediction-of-gba-carrier-status-in-parkinson-s-disease
#20
JOURNAL ARTICLE
Julia Greenberg, Kelly Astudillo, Steven J Frucht, Adeen Flinker, Giulietta M Riboldi
INTRODUCTION: Given the unique natural history of GBA -related Parkinson's disease ( GBA -PD) and the potential for novel treatments in this population, genetic testing prioritization for the identification of GBA -PD patients is crucial for prognostication, individualizing treatment, and stratification for clinical trials. Assessing the predictive value of certain clinical traits for the GBA -variant carrier status will help target genetic testing in clinical settings where cost and access limit its availability...
2024: Clinical parkinsonism & related disorders
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