Brennen McKenzie, Matthew Peloquin, Ashley Tovar, Jessica L Graves, Ellen Ratcliff, Katya Tucker, Kenny Vo, Karen Greenwood, Celine-Lea Halioua-Haubold, Dina Juarez-Salinas
OBJECTIVE: The goal of this study was to characterize changes induced by a high-fat diet in body composition, insulin levels and sensitivity, blood lipids, and other key biomarkers also associated with the metabolic dysfunction that occurs with natural aging. ANIMALS: 24 male Beagle dogs, 3 to 7 years of age, of mixed castration status. METHODS: Dogs were randomly assigned to continue twice daily feeding of the commercial adult maintenance diet (n = 12, including 2 intact) that they were previously fed or to a high-fat diet (12, including 2 intact) for 17 weeks between December 1, 2021, and April 28, 2022...
April 15, 2024: American Journal of Veterinary Research