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https://www.readbyqxmd.com/read/28792985/pulmonary-foreign-body-granulomatosis-in-a-chronic-user-of-powder-cocaine
#1
Shruti Khurana, Ankit Chhoda, Sandeep Sahay, Priyanka Pathania
We describe the case of a 33-year-old man, a chronic user of powder cocaine, who presented with dyspnea, fever, night sweats, and significant weight loss. Chest HRCT revealed centrilobular nodules, giving an initial impression of miliary tuberculosis. Therefore, he was started on an empirical, four-drug antituberculosis treatment regimen. Four weeks later, despite the tuberculosis treatment, he continued to have the same symptoms. We then performed transbronchial lung biopsy. Histopathological analysis of the biopsy sample revealed birefringent foreign body granuloma...
August 3, 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28782323/disseminated-cryptococcosis-mimicking-miliary-tuberculosis-with-generalized-lymphadenopathy-in-immunocompetent-host
#2
Sompal, Manoj Gupta, Shishir Soni, Rohit Mehtani, Anil Bharani
Cryptococcosis is a rare opportunistic infection in the immunocompromised host.1,2 Diagnosis of disseminated fungal infections is rarely thought of in immunocompetent hosts. In developing countries where tuberculosis is endemic, Cryptococcosis is often misdiagnosed as tuberculosis.3,4 A 14 year old girl, misdiagnosed as miliary tuberculosis with Koch's abdomen on ATT, presented with seizures. After extensive workup, she was found to have disseminated Cryptococcosis, not tuberculosis. This case report shows the similarity in presentation of tuberculosis and Cryptococcosis, and hence Cryptococcosis should always be kept as a differential diagnosis of tuberculosis...
June 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28776524/pulmonary-tuberculosis-in-a-pediatric-reference-hospital-in-bogot%C3%A3-colombia
#3
Luisa Fernanda Imbachí Yunda, Eileen Viviana Fonseca Sepúlveda, Kelly Christina Márquez Herrera, Germán Camacho Moreno
BACKGROUND: In Colombia, epidemiological and clinical information related to pediatric tuberculosis (TB) is scarce. Data are needed to define the impact of the disease and to strengthen measures for detection and treatment. It is proposed to analyze the pediatric population diagnosed with pulmonary TB in a national reference institution. METHODS: Retrospective observational study including pediatric patients with pulmonary and miliary TB, and pulmonary and extrapulmonary involvement, treated between January 1, 2008 and December 31, 2016...
July 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28767710/correction-a-scoring-system-to-effectively-evaluate-central-nervous-system-tuberculosis-in-patients-with-miliary-tuberculosis
#4
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0176651.].
2017: PloS One
https://www.readbyqxmd.com/read/28748775/reduction-in-extrapulmonary-tuberculosis-in-context-of-antiretroviral-therapy-scale-up-in-rural-south-africa
#5
J C Hoogendoorn, L Ranoto, N Muditambi, J Railton, M Maswanganyi, H E Struthers, J A McIntyre, R P H Peters
Scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection has reduced the incidence of pulmonary tuberculosis (PTB) in South Africa. Despite the strong association of HIV infection with extrapulmonary tuberculosis (EPTB), the effect of ART on the epidemiology of EPTB remains undocumented. We conducted a retrospective record review of patients initiated on treatment for EPTB in 2009 (ART coverage <5%) and 2013 (ART coverage 41%) at four public hospitals in rural Mopani District, South Africa...
September 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28743416/asymptomatic-choroidal-tubercle-in-a-patient-with-crohn-s-disease-on-adalimumab-treatment
#6
V M Asensio-Sánchez, L Díaz-Cabanas, A Martín-Prieto, B Haro-Álvarez
INTRODUCTION: Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. CASE REPORT: The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study...
July 22, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28743405/miliary-tuberculosis-during-adalimumab-therapy-in-crohn-s-disease
#7
Eugenia Ameneiros-Lago, José Angel Vázquez Bueno, Juan Antonio Garrido Sanjuan
No abstract text is available yet for this article.
July 22, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28721513/does-pyuria-always-suggest-urinary-tract-infection-with-common-microorganisms-questions
#8
Mehmet Taşdemir, Hüseyin Kaya, Zeynep Atam Taşdemir
Genitourinary system tuberculosis (GUTB) is a chronic granulomatous infection in which tuberculous bacilli affect one or more organs in the genitourinary system. In this report, an unusual presentation of miliary tuberculosis was presented as GUTB. A 15-year-old girl presented with complaints of severe abdominal pain and dysuria. Abdominal examination showed tenderness and defense. Pyuria and microscopic hematuria were observed. Acute abdominal causes could not be excluded through abdominal ultrasound. On abdominal computed tomography, a necrotic lesion was detected in the right kidney...
July 18, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28690859/case-report-of-a-lupus-patient-with-a-severe-flare-and-miliary-tuberculosis-need-for-proper-guidelines-for-management
#9
Masooma Hashmat, Ramsa Suhail Rana, Tafazzul-E-Haque Mahmud, Aflak Rasheed, Ata Ur Rehman, Syed Ali Rukh Pirzada, Muhammad Ammad Asghar, Sadia Asif, Amjad Ali
Systemic lupus erythematosus (SLE) is an autoimmune disease that is frequently treated with high doses of corticosteroids and other immunosuppressive drugs. Thus patients with SLE are at increased risk for infections with several pathogens including Mycobacterium tuberculosis. There are no established guidelines available for treatment of tuberculosis in SLE patients with high disease activity due to lack of relevant studies and management based more on physician expertise. We report a case of a young SLE patient with high disease activity index (SLEDAI19) as evidenced by the presence of a vasculitic rash, non-healing ulcer on forearm and proteinuria of >1 g/d along with miliary tuberculosis...
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28690472/lung-adenocarcinoma-with-miliary-metastases-and-left-femur-pathologic-fracture-an-unusual-case-mimicking-disseminated-tuberculosis
#10
Nasim Khadem, Cristina Costales, Eric A White, Dakshesh B Patel, Anderanik Tomasian, George R Matcuk
No abstract text is available yet for this article.
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28658113/the-changing-epidemiology-of-tuberculosis-in-a-spanish-tertiary-hospital-1995-2013
#11
Andrés González-García, Jesús Fortún, Enrique Elorza Navas, Pilar Martín-Dávila, Marta Tato, Enrique Gómez-Mampaso, Santiago Moreno
Important epidemiological changes and improvement of new diagnostic approaches, mainly molecular tools, might have impacted the management and outcome of tuberculosis (TB) in the last years in industrialized countries. In order to describe the epidemiological trends, and changes in clinical, diagnostic, and therapeutic aspects in patients with TB, an observational study was performed in a tertiary hospital in Western Europe (Madrid, Spain).All adult patients (>16 years) with a diagnosis of TB in the period 1995 to 2013 were included in the study...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28626190/miliary-tuberculosis-in-a-young-woman-with-hemophagocytic-syndrome-a-case-report-and-literature-review
#12
Mina Asaji, Kazunori Tobino, Koujin Murakami, Yuki Goto, Takuto Sueyasu, Saori Nishizawa, Kohei Yoshimine, Miyuki Munechika, Yuki Ko, Yuki Yoshimatsu, Kosuke Tsuruno, Hiromi Ide, Hiroyuki Miyajima, Noriyuki Ebi
We herein report a rare case of miliary tuberculosis-associated hemophagocytic syndrome (HPS) complicated with respiratory failure. A 19-year-old Japanese woman with a fever, general malaise, and chest radiograph abnormalities was referred to our hospital. After admission, she developed respiratory failure with pancytopenia. A histological examination of lung and bone marrow biopsy samples revealed noncaseating granulomas without evidence of acid-fast bacilli or lymphoma. In addition, a bone marrow biopsy showed marked histiocyte hyperplasia with hemophagocytosis, and a bronchoalveolar lavage fluid culture grew Mycobacterium tuberculosis...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28626185/miliary-tuberculosis-that-developed-after-intravesical-bacillus-calmette-guerin-therapy
#13
Kyohei Kaburaki, Keishi Sugino, Muneyuki Sekiya, Yujiro Takai, Kazutoshi Shibuya, Sakae Homma
As a treatment for superficial transitional cell carcinoma, Bacillus Calmette-Guerin (BCG) intravesical instillation can rarely cause unpredictable systemic side effects. We describe a patient admitted due to continuous pyrexia and general fatigue. He was previously treated with intravesical BCG. Laboratory data indicated a hepatic disorder, and chest computed tomography revealed extensive bilateral miliary nodules. Transbronchial lung biopsy specimens showed several small noncaseating granulomas. The diagnosis was unsolved on the basis of acid fast staining, polymerase chain reaction and microbiological cultures, so we considered the possibility of BCG side effect-induced granuloma...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28610889/high-resolution-ct-findings-of-pulmonary-tuberculosis-in-liver-transplant-patients
#14
R Schuhmacher Neto, I L Giacomelli, C Schuller Nin, J da Silva Moreira, A Comaru Pasqualotto, E Marchiori, K Loureiro Irion, B Hochhegger
AIM: To assess the high-resolution computed tomography (HRCT) findings in liver transplant patients diagnosed with pulmonary Mycobacterium tuberculosis infection. MATERIALS AND METHODS: The HRCT findings from 19 patients diagnosed with pulmonary tuberculosis infection after liver transplantation were reviewed. The patients included were 12 men and seven women, age range 23-65 years; mean age 57 years. The diagnosis was established with Mycobacterium tuberculosis detection in bronchoalveolar lavage, sputum, or biopsy...
October 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28603236/-miliary-tuberculosis-the-role-of-necropsy-studies
#15
Vitorino Modesto Dos Santos, Lister Arruda Modesto Dos Santos
This case study of generalized miliary tuberculosis in a Brazilian man without AIDS is reported in order to emphasize the role of histopathological study for diagnosis. We comment on a recent Indian study involving 40 cases of surgical and necropsy specimens in which the diagnosis of tuberculosis was made, as well as a previous Brazilian case report. The authors believe that non-specialists should be better informed about the possibility of miliary tuberculosis, which involves clinical diagnostic challenges...
June 1, 2017: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/28560175/miliary-tuberculosis-with-cerebral-liver-prostate-and-retroesophageal-involvement
#16
Raquel Goncalves, Pedro Lopes, Patrícia Mendes, João Trêpa, João Rua, Rosa Sá, Isabel Ramos, J Saraiva da Cunha
Miliary tuberculosis results from the lymphohematogenous spread of Mycobacterium tuberculosis and it is a rare form of this disease. The most affected places are the lymph nodes, pleura, and osteoarticular system, but any organ can be involved. Currently the disease is still endemic in developing countries by its close association with poor living conditions and malnutrition. Other comorbidities, particularly infection by human immunodeficiency virus (HIV), diabetes mellitus, smoking and alcoholism are of great importance in the epidemiology of this disease...
2017: IDCases
https://www.readbyqxmd.com/read/28541140/chest-ultrasound-findings-in-pulmonary-tuberculosis
#17
Paolo Agostinis, Roberto Copetti, Laura Lapini, Geraldo Badona Monteiro, Augusto N'Deque, Aldo Baritussio
In resource-limited countries, the diagnosis of pulmonary tuberculosis (TB) is based on clinical findings, chest radiography and the demonstration of acid-fast bacilli in sputum. Few data are available on the use of ultrasound (US) to diagnose pulmonary TB. Chest US was performed in patients with lung TB from a rural African setting, to look for signs of the disease and to clarify the role US may have in the diagnosis of pulmonary TB. Sixty adult patients diagnosed with lung TB underwent chest US. All patients had abnormal findings...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28531173/a-scoring-system-to-effectively-evaluate-central-nervous-system-tuberculosis-in-patients-with-military-tuberculosis
#18
Yongjiu Xiao, Shuqing Yu, Qingliang Xue, Shan Lang, Junping Sun, Dan Feng, Jianxin Wang
There is currently no convenient way to effectively evaluate whether a miliary tuberculosis patient is complicated with central nervous system (CNS) tuberculosis. We aimed to find such a way by analyzing the clinical data of these patients. Fifty patients with confirmed miliary tuberculosis and 31 patients with confirmed miliary tuberculosis complicated with CNS tuberculosis from 2010 to 2014 were selected. Their general conditions, clinical features and laboratory tests were analyzed. Factors that were significantly different between them were chosen to performed multivariate and univariate logistic regression analyses, and factors with significant P values were used to establish a scoring system...
2017: PloS One
https://www.readbyqxmd.com/read/28503298/patterns-of-ocular-inflammation-in-patients-with-miliary-tuberculosis
#19
Salil Mehta
BACKGROUND: Ocular morbidity associated with systemic tuberculosis is common. The clinical picture varies from anterior uveitis, intermediate uveitis and posterior uveitis to even panuveitis. There is little data on the correlation between specific systemic presentations and the ocular inflammation. We conducted a retrospective review of the ocular findings in the case records of patients admitted with a diagnosis of miliary tuberculosis. These patients were then referred for a more detailed ophthalmic evaluation...
2017: F1000Research
https://www.readbyqxmd.com/read/28488945/tropical-pulmonary-eosinophilia-masquerading-as-asthma-in-a-5-year-old-girl
#20
Shivani Randev, Pankaj Kumar, Prabhjot Dhillon, Geetanjali Jindal, Vishal Guglani
Tropical pulmonary eosinophilia (TPE) is an exaggerated immunological response to filarial antigens mainly seen in adults in endemic areas and is uncommonly reported in children. The diagnosis is frequently delayed as it mimics asthma clinically, while the chest radiograph might show miliary mottling which is often confused with that in pulmonary tuberculosis. A 5-year-old girl presented with episodes of nocturnal cough, wheeze, low grade fever and breathlessness for the previous 4 months and was being treated for asthma...
May 10, 2017: Paediatrics and International Child Health
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