keyword
https://read.qxmd.com/read/38459758/multicenter-evaluation-of-left-ventricular-assist-device-implantation-with-or-without-ecmo-bridge-in-cardiogenic-shock
#21
JOURNAL ARTICLE
James W Schurr, Lara Ambrosi, Jillian Fitzgerald, Christian Bermudez, Michael V Genuardi, Mark Brahier, Tonya Elliot, Kevin McGowan, Akram Zaaqoq, Sonjoy Laskar, Stuart M Pope, Michael M Givertz, Hari Mallidi, Katelyn W Sylvester, Frank C Seifert, Allison J McLarty
BACKGROUND: The efficacy of extracorporeal membrane oxygenation (ECMO) as a bridge to left ventricular assist device (LVAD) remains unclear, and recipients of the more contemporary HeartMate 3 (HM3) LVAD are not well represented in previous studies. We therefore undertook a multicenter, retrospective study of this population. METHODS AND RESULTS: INTERMACS 1 LVAD recipients from five U.S. centers were included. In-hospital and one-year outcomes were recorded. The primary outcome was the overall mortality hazard comparing ECMO versus non-ECMO patients by propensity-weighted survival analysis...
March 8, 2024: Artificial Organs
https://read.qxmd.com/read/38457524/professional-employment-with-left-ventricular-assist-device-support-does-working-with-an-lvad-allow-it-to-work-too
#22
JOURNAL ARTICLE
Sara S Inglis, Andrew N Rosenbaum
No abstract text is available yet for this article.
March 8, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38457484/ventricular-arrhythmias-and-sudden-cardiac-death-in-left-ventricular-assist-device-patients-without-implantable-cardioverter-defibrillators
#23
JOURNAL ARTICLE
Sanket Gokhale, Alexandra Malesz, Luke Masha
Patients with left ventricular assist devices (LVAD) can develop sustained ventricular arrhythmias (VA). The history and presentation of VA in implantable cardioverter defibrillator (ICD)-naive patients with LVAD is not well described in the literature and the risks/benefits of ICD implantation are unknown. This single-center retrospective cohort study included patients >18 years old who did not have an ICD during LVAD implantation from 2010 to 2022. The primary outcome was VA event rate per 100 patient-years...
March 7, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38452886/reversibility-of-precapillary-pulmonary-hypertension-and-outcomes-after-heart-transplantation-bridged-with-left-ventricular-assist-devices-insight-from-the-unos
#24
JOURNAL ARTICLE
Hilmi Alnsasra, Radha Kanneganti Perue, Fouad Khalil, Ohad Regev, Sudhir S Kushwaha, Alexandros Briasoulis, Rabea Asleh
BACKGROUND: In light of the updated lowered threshold for diagnosing pulmonary hypertension (PH), the reversibility of precapillary PH with left ventricular assist device (LVAD) and the associated post heart transplantation (HT) outcomes remain unclear. AIM AND METHODS: Using data from the United Network for Organ Sharing database, we aimed to investigate predictors of persistent precapillary PH in HT recipients bridged with LVAD, and examine the interrelated post-HT survival, using the updated pulmonary vascular resistance (PVR) cutoff of >2 WU for precapillary PH...
March 5, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38451550/withdrawal-of-left-ventricular-assist-device-in-dementia-a-case-report
#25
JOURNAL ARTICLE
Nicholas E Morley, Cristina M Ramirez-Urquiola, Shunichi Nakagawa
Left ventricular assistance devices (LVADs) are one type of life support with the unique quality of allowing recipients to live outside the hospital. This case report explores the decision by a patient and their family to withdraw LVAD therapy in the setting of dementia and consultant team recommendations at odds with one another due to the patient's simultaneous alertness and lack of decisional capacity. It then discusses the guiding principles that led to the withdrawal of LVAD therapy and lessons drawn from the experience by the care team...
March 6, 2024: Journal of Palliative Medicine
https://read.qxmd.com/read/38451441/left-ventricular-assist-devices-yesterday-today-and-tomorrow
#26
REVIEW
Athanasios Tsiouris, Mark S Slaughter, Ashok Kumar Coimbatore Jeyakumar, Adam N Protos
The shortcomings of expense, power requirements, infection, durability, size, and blood trauma of current durable LVADs have been recognized for many years. The LVADs of tomorrow aspire to be fully implantable, durable, mitigate infectious risk, mimic the pulsatile nature of the native cardiac cycle, as well as minimize bleeding and thrombosis. Power draw, battery cycle lifespan and trans-cutaneous energy transmission remain barriers to completely implantable systems. Potential solutions include decreases in pump electrical draw, improving battery lifecycle technology and better trans-cutaneous energy transmission, potentially from Free-range Resonant Electrical Energy Delivery...
March 7, 2024: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://read.qxmd.com/read/38446866/the-longest-living-patient-supported-with-left-ventricular-assist-device-14-years
#27
JOURNAL ARTICLE
Ann Hallberg Kristensen, Peter Svenarud, Lars H Lund, Emil Najjar
Left ventricular assist devices (LVADs) improve survival and reduce symptoms in patients with advanced heart failure; however, the longer-term durability of LVADs remains uncertain especially with older-generation devices. In this case report, we describe the clinical course of a patient who has been successfully treated with the same HeartMate II LVAD for 14 years, the longest published and still ongoing LVAD support with the same originally implanted device.
March 6, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38445327/emergency-medical-services-protocols-for-assessment-and-treatment-of-patients-with-ventricular-assist-devices
#28
JOURNAL ARTICLE
Emily L Larson, JiWon Woo, Gyeongtae Moon, Kathy Liu, Matthew Vergel, Reed Jenkins, Kelly Jiang, Zachary Darby, Asa Margolis, Ahmet Kilic
BACKGROUND: Patients with ventricular assist devices (VADs) represent a growing population presenting to Emergency Medical Services (EMS), but little is known about their prehospital care. This study aimed to characterize current EMS protocols in the United States for patients with VADs. METHODS: States with state-wide EMS protocols were included. Protocols were obtained from the state EMS website. If not available, the office of the state medical director was contacted...
March 6, 2024: Prehospital and Disaster Medicine
https://read.qxmd.com/read/38431240/anticoagulation-in-lvad-recipients-and-thrombembolic-complications-where-do-we-stand-where-are-we-going-to
#29
EDITORIAL
Alexander M Bernhardt, Hermann Reichenspurner
No abstract text is available yet for this article.
February 29, 2024: Journal of Heart and Lung Transplantation
https://read.qxmd.com/read/38425132/evaluation-of-erythrocyte-membrane-oxidation-due-to-their-exposure-to-shear-flow-generated-by-extracorporeal-blood-pump
#30
JOURNAL ARTICLE
Masataka Inoue, Yuki Udono, Yugo Kato, Koji Fukui, Nobuo Watanabe
Several similarities have been found between shear stress-induced erythrocyte damage and physiological aging of erythrocytes in terms of elevated mechanical fragility, increased erythrocyte aggregation, and decreased membrane surface charge. Accordingly, we hypothesized that blood pump circulation, which generates shear stress, would accelerate erythrocyte aging, manifesting as oxidation. Therefore, the purpose of this study was to investigate the effect of blood pump circulation on erythrocyte oxidation. Fresh porcine blood was acquired from a slaughterhouse and anticoagulated with sodium citrate...
February 29, 2024: International Journal of Artificial Organs
https://read.qxmd.com/read/38420779/egfr-trajectory-in-lvad-recipients-with-right-heart-failure-status-quo-or-a-steady-decline
#31
EDITORIAL
Bethany Roehm, Arianne C Agdamag
No abstract text is available yet for this article.
February 29, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38420763/kidney-function-trajectories-and-right-heart-failure-following-lvad-implantation
#32
JOURNAL ARTICLE
Carl P Walther, Andrew B Civitello, Harveen K Lamba, Nandan K Mondal, Sankar D Navaneethan
BACKGROUND: Preoperative kidney dysfunction is a risk factor for right heart failure (RHF) after implantation of a left ventricular assist device (LVAD). However, characteristic kidney function trajectories before and after post-LVAD RHF are uncertain, so we investigated this. METHODS AND RESULTS: We identified individuals who received primary continuous-flow LVAD implantation from July 1, 2014 to December 31, 2017 in the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) data set...
February 29, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38419587/successful-explantation-of-children-from-the-berlin-heart-excor%C3%A2-ventricular-assist-device-a-systematic-review
#33
REVIEW
Matthew F Mikulski, Swati Iyer, Andrew Well, Carlos M Mery, W Richard Owens, Lauren D Glass, Chesney D Castleberry, Charles D Fraser
BACKGROUND: The Berlin Heart EXCOR® (BHE) can bridge children with severe heart failure to transplantation, but some are successfully weaned and spared transplantation. This study seeks to identify characteristics of children amenable to successful explantation with BHE support. METHODS: Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines were used. Five databases were screened for original, English articles measuring BHE support in patients <18 years old based on title and abstract...
February 29, 2024: Artificial Organs
https://read.qxmd.com/read/38418690/effect-of-rvad-cannulation-length-on-right-ventricular-thrombosis-risk-an-in-silico-investigation
#34
JOURNAL ARTICLE
Kar Ying Thum, Sam Liao, Michael Šeman, Mehrdad Khamooshi, Josie Carberry, David McGiffin, Shaun D Gregory
Left ventricular assist devices (LVADs) have been used off-label as long-term support of the right heart due to the lack of a clinically approved durable right VAD (RVAD). Whilst various techniques to reduce RVAD inflow cannula protrusion have been described, the implication of the protrusion length on right heart blood flow and subsequent risk of thrombosis remains poorly understood. This study investigates the influence of RVAD diaphragmatic cannulation length on right ventricular thrombosis risk using a patient-specific right ventricle in silico model validated with particle image velocimetry...
February 28, 2024: Annals of Biomedical Engineering
https://read.qxmd.com/read/38414699/comparing-the-efficacy-and-safety-of-warfarin-monotherapy-vs-warfarin-and-aspirin-for-adult-patients-with-left-ventricular-assist-devices-a-meta-analysis
#35
REVIEW
Revanth Reddy Bandaru, Anurag Rawat, Illahay Jalali, Abraham K Isaak, Alahed A Alrahahleh, Sohaib M Bataineh, Calvin R Wei, Shamsha Hirani
The aim of this meta-analysis was to assess the safety and efficacy of warfarin plus aspirin versus warfarin monotherapy in patients with left ventricular assist devices (LVAD). The present meta-analysis was conducted using the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Two authors systematically searched online databases, including PubMed, EMBASE, the Cochrane Library, and Web of Science from inception to December 31, 2023. Outcomes assessed in this meta-analysis included any thrombotic event, bleeding events, and all-cause mortality...
January 2024: Curēus
https://read.qxmd.com/read/38409872/the-safety-of-sodium-glucose-transporter-2-inhibitors-and-trends-in-clinical-and-hemodynamic-parameters-in-patients-with-left-ventricular-assist-devices
#36
JOURNAL ARTICLE
Alexander Fardman, Afek Kodesh, Allison Joyce Siegel, Amitai Segev, Ehud Regev, Elad Maor, Anat Berkovitch, Rafael Kuperstein, Avi Morgan, Eyal Nahum, Yael Peled, Avishay Grupper
BACKGROUND: The safety and impact of sodium glucose transporter 2 inhibitors (SGLT2-I) in patients with left ventricular assist devices (LVAD) are unknown. METHODS: A retrospective analysis of all consecutive patients who underwent LVAD Heart Mate 3 (HM3) implantation at a single medical center and received SGLT2-I therapy following surgery was conducted. LVAD parameters, medical therapy, laboratory tests, echocardiography, and right heart catheterization (RHC) study results were recorded and compared before and after initiation of SGLT2-I...
February 26, 2024: Artificial Organs
https://read.qxmd.com/read/38409825/longitudinal-cardiac-dimensions-in-patients-undergoing-lvad-implantation
#37
JOURNAL ARTICLE
Florian Meissner, Sophie Szvetics, Michelle Costa Galbas, Maximilian Russe, David Schibilsky, Klaus Kaier, Martin Czerny, Wolfgang Bothe
BACKGROUND: In conventional left ventricular assist devices (LVAD), a separate outflow graft is sutured to the ascending aorta. Novel device designs may include a transventricular outflow cannula crossing the aortic valve (AV). While transversal ventricular dimensions are well investigated in patients with severe heart failure, little is known about the longitudinal dimensions. These dimensions are, however, particularly critical for the design and development of mechanical circulatory support (MCS) devices with transaortic outflow cannula...
February 26, 2024: Artificial Organs
https://read.qxmd.com/read/38402951/right-heart-reserve-function-assessed-with-fluid-loading-predicts-late-right-heart-failure-after-left-ventricular-assist-device-implantation
#38
JOURNAL ARTICLE
Masaki Tsuji, Takahiro Kurihara, Yoshitaka Isotani, Chie Bujo, Junichi Ishida, Eisuke Amiya, Masaru Hatano, Asako Shimada, Hiroko Imai, Mitsutoshi Kimura, Shogo Shimada, Masahiko Ando, Minoru Ono, Issei Komuro
BACKGROUND: A left ventricular assist device (LVAD) is an effective therapeutic option for advanced heart failure. Late right heart failure (LRHF) is a complication after LVAD implantation associated with increasing morbidity and mortality; however, the assessment of right heart function, including right heart reserve function after LVAD implantation, has not been established. We focused on a fluid loading test with right heart catheterization (RHC) to evaluate right heart pre-load reserve function and investigate its impact on LRHF...
February 23, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38400624/absorbable-antibiotic-beads-for-treatment-of-lvad-driveline-infections
#39
Ishaq Wadiwala, Pankaj Garg, Emad Alamouti-Fard, Kevin Landolfo, Basar Sareyyupoglu, Magdy El-Sayed Ahmed, Samuel Jacob, Si Pham
BACKGOUND: Infections of the left ventricular assist device (LVAD) driveline are a dreaded complication that results in high mortality and morbidity. METHOD: We retrospectively reviewed five consecutive patients with severe continuous-flow LVAD (HVAD, Heartmate 2, and Heartmate 3) driveline infection. These infections, which developed on an average of 960.4 ± 843.9 days after LVAD placement, were refractory to systemic antibiotics and local wound care...
February 23, 2024: Artificial Organs
https://read.qxmd.com/read/38400282/ventricular-arrhythmias-in-left-ventricular-assist-device-patients-current-diagnostic-and-therapeutic-considerations
#40
REVIEW
Laura Załucka, Ewa Świerżyńska, Michał Orczykowski, Krzysztof Dutkowski, Jarosław Szymański, Jarosław Kuriata, Rafał Dąbrowski, Piotr Kołsut, Łukasz Szumowski, Maciej Sterliński
Left ventricular assist devices (LVAD) are used in the treatment of advanced left ventricular heart failure. LVAD can serve as a bridge to orthotopic heart transplantation or as a destination therapy in cases where orthotopic heart transplantation is contraindicated. Ventricular arrhythmias are frequently observed in patients with LVAD. This problem is further compounded as a result of diagnostic difficulties arising from presently available electrocardiographic methods. Due to artifacts from LVAD-generated electromagnetic fields, it can be challenging to assess the origin of arrhythmias in standard ECG tracings...
February 8, 2024: Sensors
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