keyword
MENU ▼
Read by QxMD icon Read
search

PET/MR

keyword
https://www.readbyqxmd.com/read/28090451/potential-of-pet-mri-for-imaging-of-non-oncologic-musculoskeletal-disease
#1
REVIEW
Feliks Kogan, Audrey P Fan, Garry E Gold
Early detection of musculoskeletal disease leads to improved therapies and patient outcomes, and would benefit greatly from imaging at the cellular and molecular level. As it becomes clear that assessment of multiple tissues and functional processes are often necessary to study the complex pathogenesis of musculoskeletal disorders, the role of multi-modality molecular imaging becomes increasingly important. New positron emission tomography-magnetic resonance imaging (PET-MRI) systems offer to combine high-resolution MRI with simultaneous molecular information from PET to study the multifaceted processes involved in numerous musculoskeletal disorders...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28075185/cerebellar-heterogeneity-and-its-impact-on-pet-data-quantification-of-5-ht-receptor-radioligands
#2
Melanie Ganz, Ling Feng, Hanne Demant Hansen, Vincent Beliveau, Claus Svarer, Gitte M Knudsen, Douglas N Greve
In the quantification of positron emission tomography (PET) radiotracer binding, a commonly used method is reference tissue modeling (RTM). RTM necessitates a proper reference and a ubiquitous choice for G-protein coupled receptors is the cerebellum. We investigated regional differences in uptake within the grey matter of the cerebellar hemispheres (CH), the cerebellar white matter (CW), and the cerebellar vermis (CV) for five PET radioligands targeting the serotonin system. Furthermore, we evaluated the impact of choosing different reference regions when quantifying neocortical binding...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28074380/usefulness-of-diffusion-weighted-mr-imaging-for-differentiating-between-warthin-s-tumor-and-oncocytoma-of-the-parotid-gland
#3
Hiroki Kato, Keita Fujimoto, Masayuki Matsuo, Keisuke Mizuta, Mitsuhiro Aoki
PURPOSE: To assess the efficacy of diffusion-weighted (DW) MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland. METHODS: Forty-five histopathologically confirmed parotid gland tumors (41 Warthin's tumors and 4 oncocytomas) were examined by MR imaging including DW imaging. (18)F-fluorodeoxyglucose PET/CT was also performed in 9 Warthin's tumors and 3 oncocytomas. We retrospectively reviewed the images and compared the MR signal intensities, apparent diffusion coefficients (ADCs), and maximum standardized uptake values (SUVmax) of the solid components between the two pathologies...
January 10, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28066808/effect-of-mr-imaging-contrast-thresholds-on-prediction-of-neoadjuvant-chemotherapy-response-in-breast-cancer-subtypes-a-subgroup-analysis-of-the-acrin-6657-i-spy-1-trial
#4
Wen Li, Vignesh Arasu, David C Newitt, Ella F Jones, Lisa Wilmes, Jessica Gibbs, John Kornak, Bonnie N Joe, Laura J Esserman, Nola M Hylton
Functional tumor volume (FTV) measurements by dynamic contrast-enhanced magnetic resonance imaging can predict treatment outcomes for women receiving neoadjuvant chemotherapy for breast cancer. Here, we explore whether the contrast thresholds used to define FTV could be adjusted by breast cancer subtype to improve predictive performance. Absolute FTV and percent change in FTV (ΔFTV) at sequential time-points during treatment were calculated and investigated as predictors of pathologic complete response at surgery...
December 2016: Tomography: a Journal for Imaging Research
https://www.readbyqxmd.com/read/28063406/contemporary-imaging-of-incidentally-discovered-adrenal-masses
#5
REVIEW
Daniel J Wale, Ka Kit Wong, Benjamin L Viglianti, Domenico Rubello, Milton D Gross
Adrenal lesions are routinely encountered incidentally in clinical practice. Although most of these lesions are benign, malignancy needs to be excluded. Therefore, the initial clinical workup is to exclude aggressive characteristics suggesting malignancy and to identify characteristics predictive of the most common benign lesion, an adrenal adenoma. Predicting a benign adenoma using a variety of imaging modalities has been widely studied using unenhanced computed tomography (CT), contrast enhanced CT, and magnetic resonance (MR) imaging...
January 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28062597/the-effect-of-susceptibility-artifacts-related-to-metal-implants-on-adjacent-lesion-assessment-in-simultaneous-tof-pet-mr
#6
Hanna Svirydenka, Gaspar Delso, Felipe DE Galiza Barbosa, Martin W Huellner, Helen Davison, Stefano Fanti, Patrick Veit-Haibach, Edwin Ter Voert
OBJECTIVE: Metal implants could affect the attenuation correction (AC) in positron emission tomography (PET)/magnetic resonance (MR) imaging. The purpose of this study is to evaluate the effect of susceptibility artifacts related to metal implants on adjacent metabolically active lesions in clinical simultaneous PET/MR scanning for both time-of-flight (TOF) and non-TOF reconstructed PET images. METHODS: We included 27 patients without implants, but with confirmed 2-deoxy-2-(18)F-fluoro-D-glucose ((18)F-FDG) avid lesions adjacent to common implant locations...
January 6, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28058674/quantitative-myocardial-blood-flow-imaging-with-integrated-time-of-flight-pet-mr
#7
Tanja Kero, Jonny Nordström, Hendrik J Harms, Jens Sörensen, Håkan Ahlström, Mark Lubberink
BACKGROUND: The use of integrated PET-MR offers new opportunities for comprehensive assessment of cardiac morphology and function. However, little is known on the quantitative accuracy of cardiac PET imaging with integrated time-of-flight PET-MR. The aim of the present work was to validate the GE Signa PET-MR scanner for quantitative cardiac PET perfusion imaging. Eleven patients (nine male; mean age 59 years; range 46-74 years) with known or suspected coronary artery disease underwent (15)O-water PET scans at rest and during adenosine-induced hyperaemia on a GE Discovery ST PET-CT and a GE Signa PET-MR scanner...
December 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/28055827/joint-mr-pet-reconstruction-using-a-multi-channel-image-regularizer
#8
Florian Knoll, Martin Holler, Thomas Koesters, Ricardo Otazo, Kristian Bredies, Daniel K Sodickson
While current state of the art MR-PET scanners enable simultaneous MR and PET measurements, the acquired data sets are still usually reconstructed separately. We propose a new multi-modality reconstruction framework using second order Total Generalized Variation (TGV) as a dedicated multi-channel regularization functional that jointly reconstructs images from both modalities. In this way, information about the underlying anatomy is shared during the image reconstruction process while unique differences are preserved...
January 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28050631/head-to-head-comparison-between-18-f-fdopa-pet-ct-and-mr-ct-angiography-in-clinically-recurrent-head-and-neck-paragangliomas
#9
Céline Heimburger, Francis Veillon, David Taïeb, Bernard Goichot, Sophie Riehm, Julie Petit-Thomas, Gerlinde Averous, Marcela Cavalcanti, Fabrice Hubelé, Gerard Chabrier, Izzie Jacques Namer, Anne Charpiot, Alessio Imperiale
PURPOSE: Head and neck paragangliomas (HNPGLs) can relapse after primary treatment. Optimal imaging protocols have not yet been established for posttreatment evaluation. The aim of the present study was to assess the diagnostic value of (18)F-FDOPA PET/CT and MR/CT angiography (MRA/CTA) in HNPGL patients with clinical relapse during their follow-up. METHODS: Sixteen consecutive patients presenting with local pain, tinnitus, dysphagia, hoarse voice, cranial nerve involvement, deafness, or retrotympanic mass appearing during follow-up after the initial treatment of HNPGLs were retrospectively evaluated...
January 3, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28048894/su-f-i-58-image-quality-comparisons-of-different-motion-magnitudes-and-tr-values-in-mr-pet
#10
J Patrick, M Tavallaei, R Thompson, R Stodilka, M Drangova, S Gaede
PURPOSE: The aim of this work is to evaluate the accuracy and sensitivity of a respiratory-triggered MR-PET protocol in detecting four different sized lesions at two different magnitudes of motion, with two different TR values, using a novel PET-MR-CT compatible respiratory motion phantom. METHODS: The eight-compartment torso phantom was setup adjacent to the motion stage, which moved four spherical compartments (28, 22, 17, 10 mm diameter) in two separate (1 and 2 cm) linear motion profiles, simulating a 3...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048792/mo-de-206-01-cellular-metabolism-of-fdg
#11
G Pratx
: In this symposium jointly sponsored by the World Molecular Imaging Society (WMIS) and the AAPM, luminary speakers on imaging metabolism will discuss three impactful topics. The first presentation on Cellular Metabolism of FDG will be given by Guillem Pratx (Stanford). This presentation will detail new work on looking at how the most common molecular imaging agent, fluoro-deoxy-glucose is metabolized at a cellular level. This will be followed by a talk on an improved approach to whole-body PET imaging by Simon Cherry (UC Davis)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048790/su-f-j-112-clinical-feasibility-test-of-an-rf-pulse-based-mri-method-for-the-quantitative-fat-water-segmentation
#12
S Yee, J Wloch, M Pirkola
PURPOSE: Quantitative fat-water segmentation is important not only because of the clinical utility of fat-suppressed MRI images in better detecting lesions of clinical significance (in the midst of bright fat signal) but also because of the possible physical need, in which CT-like images based on the materials' photon attenuation properties may have to be generated from MR images; particularly, as in the case of MR-only radiation oncology environment to obtain radiation dose calculation or as in the case of hybrid PET/MR modality to obtain attenuation correction map for the quantitative PET reconstruction...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048774/su-f-j-215-non-thermal-pulsed-high-intensity-focused-ultrasound-therapy-combined-with-5-aminolevulinic-acid-an-in-vivo-pilot-study
#13
B Wang, W He, D Cvetkovic, L Chen, C Ma
PURPOSE: It has recently been shown that non-thermal pulsed high intensity focused ultrasound (pHIFU) has a cell-killing effect. The purpose of the study is to investigate the sonosensitizing effect of 5-Aminolevulinic Acid (5-ALA) in non-thermal pHIFU cancer therapy. METHODS: FaDu human head and neck squamous cell carcinoma cells were injected subcutaneously in the flanks of nude mice. After one to two weeks, the tumors reached the volume of 112 ± 8 mm3 and were assigned randomly into a non-thermal pHIFU group (n=9) and a non-thermal sonodynamic therapy (pHIFU after 5-ALA administration) group (n=7)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048700/tu-d-bra-00-treatment-planning-system-commissioning-and-qa
#14
Greg Salomons
INTRODUCTION: Treatment planning systems (TPS) are a cornerstone of modern radiation therapy. Errors in their commissioning or use can have a devastating impact on many patients. To support safe and high quality care, medical physicists must conduct efficient and proper commissioning, good clinical integration, and ongoing quality assurance (QA) of the TPS. AAPM Task Group 53 and related publications have served as seminal benchmarks for TPS commissioning and QA over the past two decades...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048511/su-d-207a-02-possible-characterization-of-the-brain-tumor-vascular-environment-by-a-novel-strategy-of-quantitative-analysis-in-dynamic-contrast-enhanced-mr-imaging-a-combination-of-both-patlak-and-logan-analyses
#15
S Yee, P Chinnaiyan, J Wloch, M Pirkola, D Yan
PURPOSE: The majority of quantitative analyses involving dynamic contrast enhanced (DCE) MRI have been performed to obtain kinetic parameters such as Ktrans and ve. Such analyses are generally performed assuming a "reversible" tissue compartment, where the tracer is assumed to be rapidly equilibrated between the plasma and tissue compartments. However, some tumor vascular environments may be more suited for a "non-reversible" tissue compartment, where, as with FDG PET imaging, the tracer is continuously deposited into the tissue compartment (or the return back to the plasma compartment is very slow in the imaging time scale)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048460/su-f-t-477-investigation-of-defgel-dosimetry-using-mri
#16
C Matrosic, A McMillan, J Holmes, B Bednarz, W Culberson
PURPOSE: The DEFGEL dosimeter/phantom allows for the measurement of 3D dose distributions while maintaining tissue equivalence and deformability. Although DEFGEL is traditionally read out with optical CT, the use of MRI would permit the measurement of 3D dose distributions in optically interfering configurations, like while embedded in a phantom. To the knowledge of the authors, this work is the first investigation that uses MRI to measure dose distributions in DEFGEL dosimeters. METHODS: The DEFGEL (6%T) formula was used to create 1 cm thick, 4...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048371/we-g-209-01-digital-radiography
#17
B Schueler
: Digital radiography, CT, PET, and MR are complicated imaging modalities which are composed of many hardware and software components. These components work together in a highly coordinated chain of events with the intent to produce high quality images. Acquisition, processing and reconstruction of data must occur in a precise way for optimum image quality to be achieved. Any error or unexpected event in the entire process can produce unwanted pixel intensities in the final images which may contribute to visible image artifacts...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048135/mo-de-206-02-cellular-metabolism-of-fdg
#18
S Cherry
: In this symposium jointly sponsored by the World Molecular Imaging Society (WMIS) and the AAPM, luminary speakers on imaging metabolism will discuss three impactful topics. The first presentation on Cellular Metabolism of FDG will be given by Guillem Pratx (Stanford). This presentation will detail new work on looking at how the most common molecular imaging agent, fluoro-deoxy-glucose is metabolized at a cellular level. This will be followed by a talk on an improved approach to whole-body PET imaging by Simon Cherry (UC Davis)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048038/tu-d-bra-01-tps-commissioning-and-qa-planning-and-monitoring
#19
G Salomons
INTRODUCTION: Treatment planning systems (TPS) are a cornerstone of modern radiation therapy. Errors in their commissioning or use can have a devastating impact on many patients. To support safe and high quality care, medical physicists must conduct efficient and proper commissioning, good clinical integration, and ongoing quality assurance (QA) of the TPS. AAPM Task Group 53 and related publications have served as seminal benchmarks for TPS commissioning and QA over the past two decades...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047779/we-h-207a-08-characterization-of-a-broad-spectrum-cancer-targeted-mri-contrast-agent
#20
C Brunnquell, R Zhang, A Pinchuk, J Weichert
PURPOSE: To characterize the relaxation properties and tumor targeting capabilities of a novel alkylphosphocholine (APC) analog MR contrast agent, Gd-DO3A-404. METHODS: Relaxivities were measured via T1 and T2 mapping of Gd-DO3A-404 with inversion recovery and spin echo pulse sequences, respectively. Uptake was characterized in flank xenograft models of non-small cell lung cancer (A549) and glioma (U87) and compared with uptake of Dotarem. Mice (N=3 per model per agent) were delivered 2...
June 2016: Medical Physics
keyword
keyword
42739
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"