Atheroesclerosis

INTRODUCTION: Metabolic syndrome (MS) in children has been associated to subclinical atherosclerosis as estimated by carotid intima-media thickness (CIMT). OBJECTIVES: We aim to ascertain the influence of MS, insulin resistance (IR) and nutritional status on CIMT. Percentiles with an increased risk of CIMT were also explored. METHODS: A cross-sectional study of 447 children attending public schools in Santiago, Chile, was performed during years 2009-2011...

INTRODUCTION: In general, infection and chronic inflammation have been implied as etiologic agents for atheroesclerosis and in particular coronary illness (CI). Several studies have correlated the infection of Helicobacter pylori with CI, especially with virulent strains (lineage Cag A). OBJECTIVE: Demonstrate the immunohistochemical presence of H. Pylori in atheroscletotic plaques obtained from endarterectomy of different vascular regions. MATERIAL AND METHODS: 34 atherosclerotic plaques of different vascular areas were studied, (25 men and 9 women)...

Genetic and environmental factors influence the process of aging. Longevity is extraordinarily constant along species and there are several genes that regulate it. Special consideration deserve apoprotein E alleles, specially allele eee4 that is associated with development of Alzheimer disease, atheroesclerosis and a shorter life. However environmental influences on longevity are of utmost importance. In rats, mice and non human primates, caloric restriction prolongs life and retards the appearance of several conditions associated with aging...