keyword
https://read.qxmd.com/read/38380456/an-unusual-etiology-of-fluorodeoxyglucose-avid-intrathoracic-lymph-nodes
#21
JOURNAL ARTICLE
Alyssa Bonnier, Santu Saha, Adam Austin, Biplab K Saha
A middle-aged man in his 50s, active smoker, presented to the pulmonary office for lung cancer evaluation. On a low-dose computed tomography for lung cancer screening, he was found to have an 8 mm endobronchial lesion in the right main stem bronchus. A PET-CT revealed no endobronchial lesion, but incidentally, fluorodeoxyglucose (FDG) avidity was present in the right hilar (SUV 13.2) and paratracheal lymph nodes (LNs). He underwent bronchoscopy and EBUS-TBNA of station 7 and 10 R LNs. The fine needle aspiration (FNA) revealed necrotizing epithelioid granuloma...
2024: Prague Medical Report
https://read.qxmd.com/read/38357899/early-experience-of-endobronchial-ultrasound-guided-transbronchial-nodal-cryobiopsy-a-case-series-from-sabah-malaysia
#22
JOURNAL ARTICLE
Hema Yamini Ramarmuty, Nai-Chien Huan, Larry Ellee Nyanti, Teng Shin Khoo, Tamilarasi Renganathan, Ahmad Zaki Manoh, Nusaibah Azman, Kunji Kannan Sivaraman Kannan
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an established minimally invasive method for the diagnosis of benign and malignant conditions. Continuous efforts are underway to improve the material adequacy of EBUS-TBNA, including the introduction of a new technique called EBUS-guided transbronchial nodal cryobiopsy (EBUS-TBNC). This method allows for the retrieval of larger and well-preserved histologic samples from the mediastinum. We present a case series of four patients who underwent combined EBUS-TBNA and EBUS-TBNC procedures in our centre...
2024: Therapeutic Advances in Respiratory Disease
https://read.qxmd.com/read/38355018/quantitative-evaluation-of-endobronchial-ultrasound-elastography-in-the-diagnosis-of-benign-and-malignant-mediastinal-and-hilar-lymph-nodes
#23
JOURNAL ARTICLE
Zhen Wang, Jiayu Bai, Guangyu Jiao, Peng Li
OBJECTIVE: To compare the diagnostic value of different quantitative methods of endobronchial ultrasound elastography in benign and malignant mediastinal and hilar lymph nodes. METHODS: This retrospective study included patients who underwent endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for mediastinal and hilar lymph node enlargement in our hospital between January 2019 and August 2022. We compared different quantitative elastography parameters [red area ratio (RAR, lymph node red area/lymph node area), green area ratio (GAR, lymph node green area/lymph node area), blue area ratio (SAR, lymph node blue area/lymph node area), mixed area ratio (MAR, lymph node green area/lymph node area), blue-green lymph node area/lymph node area), strain rate ratio (SR), strain rate in the target lymph node (LPA), ratio of blue area to total lymph node area outside the center of the target lymph node (PAR), and average grey value (MGV)], in order to find the best quantitative evaluation method...
February 12, 2024: Respiratory Medicine
https://read.qxmd.com/read/38352000/endobronchial-ultrasound-a-novel-screening-test-for-pulmonary-hypertension-prior-to-major-pulmonary-surgery
#24
JOURNAL ARTICLE
Nathaniel Deboever, George A Eapen, Roberto F Casal, Jean-Bernard Durand, Michael A Eisenberg, Hope Feldman, Celestino May, Zohra Ali, David C Rice, Reza J Mehran
OBJECTIVES: Pulmonary hypertension (PH) is an important physiologic variable in the assessment of patients undergoing major thoracic operations but all too often neglected because of the need for right heart catheterization (RHC) due to the inaccuracy of transthoracic echocardiography. Patients with lung cancer often require endobronchial ultrasound (EBUS) as part of the staging of the cancer. We sought to investigate whether EBUS can be used to screen these patients for PH. METHODS: Patients undergoing a major thoracic operation requiring EBUS for staging were included prospectively in the study...
February 2024: JTCVS techniques
https://read.qxmd.com/read/38349229/molecular-analysis-of-endobronchial-ultrasound-needle-aspirates-in-patients-with-non-small-cell-lung-cancer-results-from-the-scope-database
#25
JOURNAL ARTICLE
Erik Vakil, Elaine Dumoulin, Daniel Stollery, Ashley-Mae Gillson, Paul MacEachern, Inderdeep Dhaliwal, Michael Mitchell, Pen Li, Colin Schieman, Nicholas Romatowski, Alex C Chee, Chung Chun Tyan, Marc Fortin, Christopher A Hergott, Alain Tremblay
OBJECTIVE: Molecular subtyping of non-small cell lung cancer (NSCLC) is critical in the diagnostic evaluation of patients with advanced disease. This study aimed to examine whether samples from endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) of intrathoracic lymph nodes and/or lung lesions are adequate for molecular analysis across various institutions. METHODS: We retrospectively reviewed all cases of linear EBUS-TBNA with a final bronchoscopic diagnosis of NSCLC entered in the Stather Canadian Outcomes registry for chest ProcEdures database...
February 13, 2024: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://read.qxmd.com/read/38348643/insufficient-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-specimens-when-and-why-the-analysis-of-criteria-and-reasons-behind-the-insufficient-specimens
#26
JOURNAL ARTICLE
Antti Vuorisalo, Heini Huhtala, Timo Paavonen, Ivana Kholová
BACKGROUND: The classification terminology systems for pulmonary cytology specimens have recently emerged. Inadequate samples, classified as "nondiagnostic," raise challenges in determining the threshold of cell numbers and the risk of malignancy (ROM). METHODS: The study retrospectively reviewed 248 endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) samples: 46 insufficient samples, 60 low cellularity samples, and 142 adequate samples...
February 13, 2024: Diagnostic Cytopathology
https://read.qxmd.com/read/38348554/accuracy-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-for-staging-of-non-small-cell-lung-cancer
#27
JOURNAL ARTICLE
Kimberley Chung, Jacqueline Bentel, Andrew Laycock
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is routinely performed to confirm a lung cancer diagnosis and/or to clinically stage disease. EBUS-TBNA findings may be used to determine whether patients can be offered potentially curative surgery. In this study, we evaluated the reporting in our service of EBUS-TBNA cytology for early-stage (operable) non-small cell lung cancer (NSCLC), focusing on diagnostic accuracy and analyzing cases with discordant cytologic and post-surgical histopathologic conclusions...
February 13, 2024: Diagnostic Cytopathology
https://read.qxmd.com/read/38337753/a-retrospective-analysis-of-2-year-follow-up-of-patients-with-incidental-findings-of-sarcoidosis
#28
JOURNAL ARTICLE
Oluwabukola Thomas-Orogan, Shaney L Barratt, Muhammad Zafran, Apollo Kwok, Anneliese Simons, Eoin P Judge, Matthew Wells, Richard Daly, Charles Sharp, Abiramy Jeyabalan, Martin Plummeridge, Ladli Chandratreya, Lisa G Spencer, Andrew R L Medford, Huzaifa I Adamali
INTRODUCTION: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms. The appropriate follow-up of incidentally diagnosed asymptomatic stage 1 disease has not been well defined. OBJECTIVE: To define the clinical course of incidentally diagnosed asymptomatic stage 1 sarcoidosis and propose an algorithm for the follow-up of these patients...
January 23, 2024: Diagnostics
https://read.qxmd.com/read/38328474/detection-of-tumor-dna-in-bronchoscopic-fluids-in-peripheral-nsclc-a-proof-of-concept-study
#29
JOURNAL ARTICLE
Gwenaëlle Arhant, Samy Lachkar, Pierre-Alain Thiebaut, Florent Marguet, Aude Lamy, Luc Thiberville, Mathieu Salaün, Florian Guisier, Jean-Christophe Sabourin, Nicolas Piton
INTRODUCTION: DNA genotyping from plasma is a useful tool for molecular characterization of NSCLC. Nevertheless, the false-negative rate justifies the development of methods with higher sensitivity, especially in difficult-to-reach peripheral lung tumors. METHODS: We aimed at comparing molecular analysis from the supernatant of guide sheath flush fluid collected during radial-EndoBronchial UltraSound (r-EBUS) bronchoscopy with plasma sampling and tumor biopsies in patients with peripheral NSCLC...
February 2024: JTO clinical and research reports
https://read.qxmd.com/read/38326810/transbronchial-lymph-node-forceps-biopsy-as-a-novel-tool-in-diagnosis-of-mediastinal-lymphadenopathy-a-pilot-study
#30
JOURNAL ARTICLE
Ahmed Al-Halfawy, Sabah Hussein, Wafaa Ashur, Ali El-Hendawi, Sara Hussein
BACKGROUND: Differential diagnosis of mediastinal lymphadenopathy is an issue of debate. Lymph nodes may be enlarged due to a variety of inflammatory, infectious, or malignant reasons. Therefore, obtaining samples from the affected nodes is crucial for the diagnosis. Usually, these patients are subjected to TBNA (EBUS or conventional) or mediastinoscopy if TBNA is not conclusive. This study evaluated the safety and feasibility of this new technique of transbronchial forceps biopsy for the diagnosis of mediastinal lymphadenopathy...
February 7, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38322189/endobronchial-ultrasound-guided-transbronchial-mediastinal-cryobiopsy-a-narrative-review
#31
REVIEW
Hema Yamini Ramarmuty, Masahide Oki
BACKGROUND AND OBJECTIVE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive, safe, and well-established method for diagnosing and staging lung cancer and other conditions associated with mediastinal lymphadenopathy. Efforts have been made to enhance the material adequacy of EBUS-TBNA, including the recent introduction of EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TMC). This advancement facilitates the acquisition of larger and better-preserved tissue samples from the mediastinum...
2024: Mediastinum
https://read.qxmd.com/read/38318116/bacterial-pericardial-effusion-secondary-to-endobronchial-ultrasound-guided-needle-aspiration
#32
Benjamin Salwen, Dan Frechtling, Wadih Chahine, Jaime Palomino
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a widely used procedure in lung cancer diagnosis with few serious complications. We present a rare case of pericardial effusion secondary to EBUS-TBNA. An 80-year-old male with interstitial lung disease, developed a pericardial effusion composed exclusively of oropharyngeal flora following EBUS-TBNA. Bacterial pericardial effusion following EBUS-TBNA has only been reported in the literature seven previous times. The majority of these cases reported a biopsy of the 4R lymph node...
February 2024: Respirology Case Reports
https://read.qxmd.com/read/38317222/using-cryoprobes-of-different-sizes-combined-with-cone-beam-computed-tomography-derived-augmented-fluoroscopy-and-endobronchial-ultrasound-to-diagnose-peripheral-pulmonary-lesions-a-propensity-matched-study
#33
JOURNAL ARTICLE
Ching-Kai Lin, Sheng-Yuan Ruan, Hung-Jen Fan, Hao-Chun Chang, Yen-Ting Lin, Chao-Chi Ho
BACKGROUND: Endobronchial ultrasound (EBUS) and cone-beam computed tomography-derived augmented fluoroscopy (CBCT-AF) are utilized for the diagnosis of peripheral pulmonary lesions (PPLs). Combining them with transbronchial cryobiopsy (TBC) can provide sufficient tissue for genetic analysis. However, cryoprobes of different sizes have varying degrees of flexibility, which can affect their ability to access the target bronchus and potentially impact the accuracy. The aim of this study was to compare the diagnostic efficacy of cryoprobes of varying sizes in CBCT-AF and EBUS for the diagnosis of PPLs...
February 5, 2024: Respiratory Research
https://read.qxmd.com/read/38262192/application-of-rapid-on-site-evaluation-combined-with-flexible-bronchoscopy-in-the-diagnosis-of-lung-lesions
#34
JOURNAL ARTICLE
Shuang Yan, Lei Pan, Jian Chen, Hua Jiang, Li Gong, Faguang Jin
BACKGROUND: Pathology is considered the gold standard for the diagnosis of lung lesions, but the pathological result is relatively lagging and cannot provide real-time guidance for the biopsy procedure. OBJECTIVE: To investigate the potential application of rapid on-site evaluation (ROSE) during flexible bronchoscopy (FB) in the evaluation and diagnosis of lung lesions. PATIENTS AND METHODS: Consecutive patients who underwent FB for the diagnosis of lung lesions between August 2022 and February 2023 were included in this retrospective study...
April 2024: Annals of Diagnostic Pathology
https://read.qxmd.com/read/38256555/enhancing-patient-selection-in-stage-iiia-iiib-nsclc-invasive-lymph-node-restaging-after-neoadjuvant-therapy
#35
JOURNAL ARTICLE
Robert Kwiatkowski, Marcin Zieliński, Jarosław Paluch, Jadwiga Gabor, Andrzej Swinarew
Restaging of mediastinal lymph nodes plays a crucial role in the multimodal treatment of stage IIIA Non-Small-Cell Lung Cancer (NSCLC). This study aimed to assess the impact of restaging using endobronchial ultrasound (EBUS), endoesophageal ultrasound (EUS), and transcervical extended mediastinal lymphadenectomy (TEMLA) after neoadjuvant chemotherapy (CHT) or chemoradiotherapy (CRT) on the 5-year overall survival (OS) of patients with NSCLC diagnosed with clinical stage IIIA-IIIB and metastatic ipsilateral mediastinal nodes (N2) who underwent radical pulmonary resections...
January 12, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38256481/impact-of-cough-severity-on-the-diagnostic-yield-of-endobronchial-ultrasonography-transbronchial-biopsy-with-guide-sheath-a-retrospective-observational-study
#36
JOURNAL ARTICLE
Fumi Kobayashi, Takeshi Saraya, Takatora Akizawa, Taro Abe, Ryo Takagi, Eriko Ieki, Narishige Ishikawa, Nozomi Kurokawa, Jumpei Aso, Hiroki Nunokawa, Yasuo Nakamoto, Manabu Ishida, Mitsuru Sada, Keitaro Nakamoto, Saori Takata, Haruyuki Ishii
Bronchoscopy is an invasive procedure, and patient coughing during examination has been reported to cause patient distress. This study aimed to clarify the relationship between cough severity and diagnostic yield of endobronchial ultrasonography with guide sheath transbronchial biopsy (EBUS-GS-TBB). Data of patients who underwent bronchoscopy at Kyorin University Hospital between April 2019 and March 2022 were retrospectively evaluated. Bronchoscopists assessed the cough severity upon completion of the procedure using a four-point cough scale...
January 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38251856/the-first-report-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-from-an-intraparenchymal-lung-mass-in-a-child-advances-in-pediatric-ebus
#37
JOURNAL ARTICLE
Sheetal Agarwal, Kana Ram Jat, Nitin Dhochak, Saurabh Mittal, Priyanka Naranje, Aruna Nambirajan, Sachidanand Jee Bharti, Ipsita Pati, Yashika Maheshwari, Sushil Kumar Kabra, Karan Madan
No abstract text is available yet for this article.
January 22, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38249930/the-efficacy-and-safety-of-radial-endobronchial-ultrasound-guided-transbronchial-lung-cryobiopsy-in-the-diagnosis-of-lung-disease
#38
JOURNAL ARTICLE
Li Yang, Sheng Bi, Guang Wei, Dongmei Yu, Hai Wang, Jiawei Dong, Hao Wang, Ye Gu
BACKGROUND: Transbronchial lung cryobiopsy (TBLC) is a novel technology in which a cryoprobe is used to obtain large tissue samples from the lungs of patients with interstitial lung diseases (ILDs) and peripheral pulmonary lesions (PPLs). We aimed to determine the efficacy and safety of TBLC in the diagnosis of peripheral lung diseases in the Endoscopy Center of Shanghai Pulmonary Hospital. Further, the application value of radial endobronchial ultrasound (R-EBUS) used to determine the optimal area for cryobiopsy was evaluated in this study...
December 30, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/38249870/transbronchial-cryobiopsy-using-an-ultrathin-cryoprobe-with-a-guide-sheath-for-the-diagnosis-of-pulmonary-mucosa-associated-lymphoid-tissue-lymphoma
#39
JOURNAL ARTICLE
Hitomi Nogawa, Hiroki Suzuki, Hiroki Ota, Yuta Kanno, Sosuke Kume, Yusuke Agatsuma, Norio Katsuno, Sayuri Momosaki, Takafumi Aizawa, Sachie Nawa, Mari Aso, Toshihiko Hino
Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is difficult to diagnose and relatively rare. Tissue sampling through transbronchial biopsy is often inadequate, necessitating surgical lung biopsy. However, a recently developed technique, transbronchial lung cryobiopsy (TBLC), has shown promise for obtaining larger specimens. A 1.1 mm cryoprobe has recently become available, and its usefulness has been increasingly reported. Use of a conventional cryoprobe for TBLC in diagnosing pulmonary MALT lymphoma has been previously reported; however, there are no reports on the use of a 1...
December 30, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/38246887/comparison-of-the-specimen-quality-of-endobronchial-ultrasound-guided-intranodal-forceps-biopsy-using-standard-sized-forceps-versus-mini-forceps-for-lung-cancer-a-prospective-study
#40
JOURNAL ARTICLE
Toshiyuki Nakai, Yuji Matsumoto, Takahiro Ueda, Yuko Kuwae, Sayaka Tanaka, Atsushi Miyamoto, Yoshiya Matsumoto, Kenji Sawa, Kanako Sato, Kazuhiro Yamada, Tetsuya Watanabe, Kazuhisa Asai, Hideaki Furuse, Keigo Uchimura, Tatsuya Imabayashi, Riki Uenishi, Mitsuru Fukui, Hidenori Tanaka, Masahiko Ohsawa, Tomoya Kawaguchi, Takaaki Tsuchida
BACKGROUND AND OBJECTIVE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a diagnostic procedure with adequate performance; however, its ability to provide specimens of sufficient quality and quantity for treatment decision-making in advanced-stage lung cancer may be limited, primarily due to blood contamination. The use of a 0.96-mm miniforceps biopsy (MFB) permits true histological sampling, but the resulting small specimens are unsuitable for the intended applications...
January 21, 2024: Respirology: Official Journal of the Asian Pacific Society of Respirology
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