keyword
https://read.qxmd.com/read/38490228/systematic-endoscopic-staging-of-mediastinum-to-guide-radiotherapy-planning-in-patients-with-locally-advanced-non-small-cell-lung-cancer-seismic-an-international-multicentre-single-arm-clinical-trial
#1
JOURNAL ARTICLE
Daniel P Steinfort, Gargi Kothari, Neil Wallace, Nicholas Hardcastle, Kanishka Rangamuwa, Edith M T Dieleman, Percy Lee, Peixuan Li, Julie A Simpson, Shaun Yo, Farzad Bashirdazeh, Phan Nguyen, Barton R Jennings, David Fielding, Laurence Crombag, Louis B Irving, Kazuhiro Yasufuku, Jouke T Annema, David E Ost, Shankar Siva
BACKGROUND: Systematic mediastinal lymph node staging by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) improves accuracy of staging in patients with early-stage non-small-cell lung cancer (NSCLC). However, patients with locally advanced NSCLC commonly undergo only selective lymph node sampling. This study aimed to determine the proportion of patients with locally advanced NSCLC in whom systematic endoscopic mediastinal staging identified PET-occult lymph node metastases, and to describe the consequences of PET-occult disease on radiotherapy planning...
March 11, 2024: Lancet Respiratory Medicine
https://read.qxmd.com/read/38471486/transbronchial-cryobiopsy-using-the-ultrathin-1-1-mm-cryoprobe-with-ultrathin-bronchoscopy-under-radial-endobronchial-ultrasound-guidance-for-diagnosis-of-peripheral-pulmonary-lesions
#2
JOURNAL ARTICLE
Franziska Hasselbring, Felix J F Herth, Mark Kriegsmann, Katharina Kriegsmann, Ralf Eberhardt
INTRODUCTION: Today, the increasing number of incidentally detected peripheral pulmonary lesions (PPL) within and outside lung cancer screening trials is a diagnostic challenge. This fact encourages further improvement of diagnostic procedures to increase the diagnostic yield of transbronchial biopsy, which has been shown to have a low complication rate. The purpose of this study was to evaluate the safety and feasibility of a new ultrathin 1.1 cryoprobe that can be placed through an ultrathin bronchoscope using fluoroscopy and radial EBUS navigation for assessing PPLs...
March 12, 2024: Respiration; International Review of Thoracic Diseases
https://read.qxmd.com/read/38466540/endobronchial-ultrasound-transbronchial-needle-aspiration-effectiveness-and-accuracy-in-non-small-cell-lung-cancer-staging
#3
JOURNAL ARTICLE
Maria Giovanna Mastromarino, Elena Guerrini, Giacomo Rabazzi, Diana Bacchin, Alessandro Picchi, Olivia Fanucchi, Vittorio Aprile, Stylianos Korasidis, Greta Alì, Alessandro Ribechini, Marco Lucchi, Marcello Carlo Ambrogi
INTRODUCTION: Endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) has a cardinal role in the diagnosis and staging of non-small cell lung cancer (NSCLC), providing an accurate nodal staging in a less invasive way than surgical biopsy. The aim of this study was to assess the diagnostic accuracy of EBUS-TBNA in the pre-operative NSCLC mediastinal staging, as well as to evaluate EBUS-TBNA specificity and sensibility in our cohort. METHODS: We retrospectively analyzed data of NSCLC patients who underwent EBUS-TBNA followed by major pulmonary resection between January 2020 and December 2022...
March 11, 2024: Updates in Surgery
https://read.qxmd.com/read/38461020/a-49-year-old-man-with-fever-and-dyspnea-after-endobronchial-ultrasound-guided-transbronchial-fine-needle-aspiration-biopsy
#4
Zenglin Liao, Hao Wang, Jing An, Jiajia Dong, Xiaoyu Long
A 49-year-old man, a farmer, had been experiencing coughing, phlegm, and difficulty breathing for 2 months. He underwent a CT scan at a local hospital that showed a mediastinal mass. Bronchoscopy showed no obstruction in the tracheal lumen, and an endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA) biopsy was performed on the mediastinal mass. The cytologic smear of the mediastinal mass showed a few atypical epithelial cells; the possibility of a tumor could not be ruled out...
March 2024: Chest
https://read.qxmd.com/read/38457094/thoracic-manifestations-of-tularaemia-a-case-series
#5
JOURNAL ARTICLE
M Vacca, B Wilhelms, S Zange, K Avsar, W Gesierich, M Heiß-Neumann
BACKGROUND: Tularaemia is a zoonotic disease caused by Francisella tularensis, a highly virulent bacterium that affects humans and small wild animals. It is transmitted through direct contact with infected animals or indirectly through contaminated soil, water or arthropod bites (e.g. ticks). Primary thoracic manifestations of tularaemia are infrequent and, therefore, a diagnostic challenge for clinicians. METHODS: We report six tularaemia cases with exclusively thoracic involvement diagnosed in a clinic for pulmonary diseases in Bavaria between 10/2020 and 02/2022...
March 8, 2024: Infection
https://read.qxmd.com/read/38454935/a-nomogram-to-predict-benign-malignant-mediastinal-lymph-nodes-based-on-ebus-sonographic-features
#6
JOURNAL ARTICLE
Bingchao Ling, Weishun Xie, Yi Zhong, Taowen Feng, Yueli Huang, Lianying Ge, Aiqun Liu
BACKGROUND: Endobronchial ultrasound (EBUS) sonographic features help identify benign/malignant lymph nodes while conducting transbronchial needle aspiration (TBNA). This study aims to identify risk factors for malignancy based on EBUS sonographic features and to estimate the risk of malignancy in lymph nodes by constructing a nomogram. METHODS: 1082 lymph nodes from 625 patients were randomly enrolled in training ( n  = 760) and validation ( n  = 322) sets...
2024: International Journal of Clinical Practice
https://read.qxmd.com/read/38453440/-role-of-general-anesthesia-and-rapid-on-site-evaluation-%C3%A2-in-the-diagnosis-of-lung-cancer-with-ebus-tbna
#7
JOURNAL ARTICLE
Yuhe Hu, Yuying Li
BACKGROUND: Lung cancer is a common malignant tumor of respiratory system. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a valuable tool for the diagnosis and staging of lung cancer. EBUS-TBNA is predominantly performed under local anesthesia or conscious sedation. However, the diagnostic performance of EBUS-TBNA under general anesthesia and in conjunction with rapid on-site evaluation (ROSE) remains uncertain. This study aims to investigate the value of general anesthesia and ROSE in the diagnosis of lung cancer with EBUS-TBNA...
February 20, 2024: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://read.qxmd.com/read/38445307/using-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-for-the-diagnosis-and-treatment-of-a-mediastinal-mass-with-eccentric-calcifications-a-case-report
#8
JOURNAL ARTICLE
Ruba Ghalayni, Satish Gowda
Mediastinal masses present a diagnostic challenge due to their similar imaging characteristics, making distinguishing between noninfectious and infectious processes or malignancies difficult. A mediastinal abscess can result in severe life-threatening infections if left untreated. Traditional treatment approaches involve surgical debridement and drainage; however, emerging endobronchial techniques, such as endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), offer a less-invasive means of diagnosing and managing abscesses...
2024: Journal of Investigative Medicine High Impact Case Reports
https://read.qxmd.com/read/38442552/optimized-fuzzy-k-nearest-neighbor-approach-for-accurate-lung-cancer-prediction-based-on-radial-endobronchial-ultrasonography
#9
JOURNAL ARTICLE
Jie Xing, Chengye Li, Peiliang Wu, Xueding Cai, Jinsheng Ouyang
Radial endobronchial ultrasonography (R-EBUS) has been a surge in the development of new ultrasonography for the diagnosis of pulmonary diseases beyond the central airway. However, it faces challenges in accurately pinpointing the location of abnormal lesions. Therefore, this study proposes an improved machine learning model aimed at distinguishing between malignant lung disease (MLD) from benign lung disease (BLD) through R-EBUS features. An enhanced manta ray foraging optimization based on elite perturbation search and cyclic mutation strategy (ECMRFO) is introduced at first...
February 17, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38434470/is-high-flow-nasal-oxygenation-a-game-changer-in-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-a-pilot-study
#10
JOURNAL ARTICLE
Parli R Ravi, Shyam P Mantha, Asifa A Mir, Rajini Kausalya, Sami M Bennji
OBJECTIVES: This study aimed to compare the high-flow nasal oxygen (HFNO) and supraglottic airway device (SAD) techniques in oncological patients undergoing endobronchial ultrasound (EBUS) and transbronchial needle aspiration (TBNA) to evaluate the efficacy of HFNO in them. METHODS: This pilot study was conducted at Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, Oman, from May 2022 to March 2023. Patients undergoing EBUS TBNA under moderate sedation were quasi-randomised into the HFNO and SAD groups...
February 2024: Sultan Qaboos University Medical Journal
https://read.qxmd.com/read/38410610/predictors-of-improvement-of-radial-endobronchial-ultrasonography-findings-from-adjacent-to-to-within-in-endobronchial-ultrasonography-using-a-guide-sheath-a-retrospective-cohort-study
#11
JOURNAL ARTICLE
Shigenori Yamamoto, Hiroki Matsui, Haruka Fujioka, Yuya Homma, Norihiko Kubota, Ayumu Otsuki, Hiroyuki Ito, Hironori Sagara, Kei Nakashima
BACKGROUND: In flexible bronchoscopy, endobronchial ultrasonography using a guide sheath (EBUS-GS) has varying diagnostic yield depending on the findings of radial-endobronchial ultrasonography (R-EBUS). The diagnosis rate is lower when the ultrasound probe is "adjacent to", than when it is "within" the lesion. However, these findings are inconsistent, and the imaging status may change from "adjacent to" to "within" as examination progresses. In this study, we analyzed the predictive factors for this change, which remain unexplored till date...
January 30, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38410576/endobronchial-ultrasound-ebus-guided-transbronchial-miniforceps-biopsy-an-urban-center-experience
#12
JOURNAL ARTICLE
Moayad Al Sona, Oshioke Esivue, Sadia Benzaquen
BACKGROUND: The role of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in staging mediastinal and hilar lymph nodes in non-small cell lung cancer (NSCLC) is well established. However, evidence of its diagnostic utility in other pathologies-such as lymphoma-remains inadequate. This retrospective observational study aims to determine the diagnostic yield of EBUS-guided miniforceps biopsy (EBUS-MFB) compared to EBUS-TBNA in both malignant and nonmalignant conditions...
January 30, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38410574/factors-associated-with-increased-diagnostic-yield-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-an-observational-single-center-study
#13
JOURNAL ARTICLE
Beong Ki Kim, Hangseok Choi, Chi Young Kim
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an innovative tool for diagnosing mediastinal diseases. We investigated the factors affecting the diagnostic yield of EBUS-TBNA and evaluated whether the effects of these factors (number of biopsies, core tissue acquisition rate, and diameter and volume of tissue) vary depending on computed tomography (CT) and/or positron emission tomography (PET)/CT results. METHODS: We retrospectively analyzed lung cancer patients who underwent EBUS-TBNA at Korea University Ansan Hospital (January 2019-December 2022)...
January 30, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38410559/inter-and-intra-observer-variability-of-radial-endobronchial-ultrasound-image-interpretation-for-peripheral-pulmonary-lesions
#14
JOURNAL ARTICLE
Nathaniel Moulton, Mohammed Abbasi, Danish Ahmad, Allen Burks, Praveen Chenna, Kevin Haas, Andrea Loiselle, Essam Mekhaiel, Suchitra Pilli, Ali Sadoughi, Brandt Lydon, Tej Patel, Alexander C Chen
BACKGROUND: Radial probe endobronchial ultrasound (R-EBUS) is often utilized in guided bronchoscopy for the diagnosis of peripheral pulmonary lesions. R-EBUS probe positioning has been shown to correlate with diagnostic yield, but overall diagnostic yield with this technology has been inconsistent across the published literature. Currently there is no standardization for R-EBUS image interpretation, which may result in variability in grading concentricity of lesions and subsequently procedure performance...
January 30, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38404993/bronchoscopic-deployment-and-implantation-of-diffusing-alpha-emitters-radiation-therapy-into-the-lung-and-mediastinum-for-treatment-of-lung-cancer-a-pre-clinical-safety-and-feasibility-study
#15
JOURNAL ARTICLE
Ali Sadoughi, Abhishek Sarkar, Carol Novotney, Christine Chan, Gerardo Moreno, Stephanie Oren, Lior Moss, Kobi Aharoni, Saleem Eben Bari, Nir Edery, Nitin Ohri
BACKGROUND: Radiotherapy is a standard treatment modality in cancer therapy, particularly for lung cancer. Diffusing alpha-emitters Radiation Therapy sources (hereafter, "Alpha DaRTs") are fixed with Ra-244 (half-life =3.6 days) that releases alpha-emitting atoms into the tumor tissue to an effective range of a few millimeters. METHODS: The feasibility, usability, and safety of Alpha DaRTs deployment and implantation via bronchoscopy into the lung parenchyma and mediastinum in a big animal model of healthy swine was studied in two phases: (I) inert and (II) active Alpha DaRTs deployment...
January 31, 2024: Translational Lung Cancer Research
https://read.qxmd.com/read/38402862/an-international-survey-of-practices-in-the-investigation-and-endoscopic-treatment-of-peripheral-pulmonary-lesions-amongst-interventional-bronchoscopists
#16
JOURNAL ARTICLE
Thibaud Soumagne, Hervé Dutau, Georgie Eapen, Nicolas Guibert, Christopher Hergott, Fabien Maldonado, Hideo Saka, Marc Fortin
INTRODUCTION: The investigation of peripheral pulmonary lesions (PPLs) can be challenging. Several bronchoscopic modalities have been developed to reach and biopsy PPL but the level of adoption of these techniques by interventional pulmonologists (IPs) is unknown. This international survey was conducted to describe current practices in PPL investigation among IP. METHODS: This survey was sent to all members of the World Association for Bronchology and Interventional Pulmonology, Canadian Thoracic Society Procedures Assembly, AABIP, and the Groupe d'Endoscopie Thoracique et Interventionnel Francophone...
February 23, 2024: Respiration; International Review of Thoracic Diseases
https://read.qxmd.com/read/38398180/evaluation-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna-samples-from-advanced-non-small-cell-lung-cancer-for-whole-genome-whole-exome-and-comprehensive-panel-sequencing
#17
JOURNAL ARTICLE
David Fielding, Vanessa Lakis, Andrew J Dalley, Haarika Chittoory, Felicity Newell, Lambros T Koufariotis, Ann-Marie Patch, Stephen Kazakoff, Farzad Bashirzadeh, Jung Hwa Son, Kimberley Ryan, Daniel Steinfort, Jonathan P Williamson, Michael Bint, Carl Pahoff, Phan Tien Nguyen, Scott Twaddell, David Arnold, Christopher Grainge, Andrew Pattison, David Fairbairn, Shailendra Gune, Jemma Christie, Oliver Holmes, Conrad Leonard, Scott Wood, John V Pearson, Sunil R Lakhani, Nicola Waddell, Peter T Simpson, Katia Nones
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is often the only source of tumor tissue from patients with advanced, inoperable lung cancer. EBUS-TBNA aspirates are used for the diagnosis, staging, and genomic testing to inform therapy options. Here we extracted DNA and RNA from 220 EBUS-TBNA aspirates to evaluate their suitability for whole genome (WGS), whole exome (WES), and comprehensive panel sequencing. For a subset of 40 cases, the same nucleic acid extraction was sequenced using WGS, WES, and the TruSight Oncology 500 assay...
February 15, 2024: Cancers
https://read.qxmd.com/read/38398120/lions-prey-a-new-logistic-scoring-system-for-the-prediction-of-malignant-pulmonary-nodules
#18
JOURNAL ARTICLE
Fabian Doerr, Annika Giese, Katja Höpker, Hruy Menghesha, Georg Schlachtenberger, Konstantinos Grapatsas, Natalie Baldes, Christian J Baldus, Lars Hagmeyer, Hazem Fallouh, Daniel Pinto Dos Santos, Edward M Bender, Alexander Quaas, Matthias Heldwein, Thorsten Wahlers, Hubertus Hautzel, Kaid Darwiche, Christian Taube, Martin Schuler, Khosro Hekmat, Servet Bölükbas
OBJECTIVES: Classifying radiologic pulmonary lesions as malignant is challenging. Scoring systems like the Mayo model lack precision in predicting the probability of malignancy. We developed the logistic scoring system 'LIONS PREY' (Lung lesION Score PREdicts malignancY), which is superior to existing models in its precision in determining the likelihood of malignancy. METHODS: We evaluated all patients that were presented to our multidisciplinary team between January 2013 and December 2020...
February 9, 2024: Cancers
https://read.qxmd.com/read/38398119/improved-accuracy-and-sensitivity-in-diagnosis-and-staging-of-lung-cancer-with-systematic-and-combined-endobronchial-and-endoscopic-ultrasound-ebus-eus-experience-from-a-tertiary-center
#19
JOURNAL ARTICLE
Abdenor Badaoui, Marion De Wergifosse, Benoit Rondelet, Pierre H Deprez, Claudia Stanciu-Pop, Laurent Bairy, Philippe Eucher, Monique Delos, Sebahat Ocak, Cédric Gillain, Fabrice Duplaquet, Lionel Pirard
BACKGROUND: Combined endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound-guided tissue acquisition (EUS-TA) are accurate procedures for the diagnosis and staging of mediastinal lymph nodes (MLNs) in lung cancer. However, the respective contribution of separate and combined procedures in diagnosis and staging has not been fully studied. The aim of this study was to assess their respective performances. METHODS: Patients with suspected malignant MLNs in lung cancer or recurrence identified by PET-CT who underwent combined EBUS-TBNA and EUS-TA were retrospectively reviewed...
February 9, 2024: Cancers
https://read.qxmd.com/read/38380557/factors-affecting-accuracy-of-clinical-staging-in-resectable-non-small-cell-lung-cancer-in-a-real-world-study
#20
JOURNAL ARTICLE
Hye Ran Gwon, A La Woo, Seung Hyun Yong, Youngmok Park, Song Yee Kim, Eun Young Kim, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Seong Yong Park, Sang Hoon Lee
BACKGROUND: The clinical staging of non-small cell lung cancer (NSCLC) is well known to be related to their prognosis. However, there is usually a discrepancy between clinical staging and pathological staging. There are few analyses of clinical staging accuracy in patients with NSCLC. We compared the concordance rate between clinical and pathological staging of NSCLC and evaluated factors affecting the accuracy in real-world data. METHODS: Altogether, 811 patients with primary NSCLC who had undergone curative lung resection surgery in Severance Hospital from January 2019 to December 2020 were retrospectively reviewed...
February 21, 2024: Thoracic Cancer
keyword
keyword
4271
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.