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https://www.readbyqxmd.com/read/28632761/experience-improves-the-performance-of-endobronchial-ultrasound-guided-transbronchial-biopsy-for-peripheral-pulmonary-lesions-a-learning-curve-at-a-medical-centre
#1
Chun-Ta Huang, Sheng-Yuan Ruan, Yi-Ju Tsai, Chao-Chi Ho, Chong-Jen Yu
BACKGROUND: Endobronchial ultrasound(EBUS)-guided transbronchial biopsy(TBB) is the preferred diagnostic tool for peripheral pulmonary lesions(PPLs) and mastering this procedure is an important task in the training of chest physicians. Little has been published about the learning experience of physicians with this technique, particularly at an institutional level. We aimed to establish a learning curve for EBUS-guided TBB for PPLs at a medical center. METHODS: Between 2008 and 2015, consecutive patients with PPLs referred for EBUS-guided TBB at National Taiwan University Hospital were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28631880/ebus-tbna-risks-and-repairs
#2
EDITORIAL
Christina Bellinger, Travis Dotson
No abstract text is available yet for this article.
June 20, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28631863/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-safe-as-it-sounds
#3
REVIEW
Preyas J Vaidya, Mohammed Munavvar, Joerg D Leuppi, Atul C Mehta, Prashant N Chhajed
Real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has earned its place as a standard of care in the evaluation of mediastinal and hilar lymphadenopathy. It is a minimally invasive and a safe procedure with high diagnostic accuracy and efficacy. The increased usage of EBUS-TBNA worldwide has thrown light on its possible complications including death. The complications range from minor to life threatening in few and may occur either early or later in the course after the procedure...
June 20, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28625645/eus-b-fna-vs-conventional-eus-fna-for-left-adrenal-gland-analysis-in-lung-cancer-patients
#4
Laurence M M J Crombag, Artur Szlubowski, Jos A Stigt, Olga Schuurbiers, Daniël A Korevaar, Peter I Bonta, Jouke T Annema
INTRODUCTION: In patients with lung cancer, left adrenal glands (LAG) suspected for distant metastases (M1b) based on imaging require further evaluation for a definitive diagnosis. Tissue acquisition is regularly performed using conventional EUS-FNA. The aim of this study was to investigate the success rate of endoscopic ultrasound guided fine-needle aspiration using the EBUS scope (EUS-B-FNA) for LAG analysis. METHODS: This is a prospective multicenter study in consecutive patients with (suspected) lung cancer and suspected mediastinal and LAG metastases...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28621292/is-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-an-effective-diagnostic-procedure-in-restaging-of-non-small-cell-lung-cancer-patients
#5
Erdoğan Cetinkaya, Ozan Usluer, Aydın Yılmaz, Nuri Tutar, Ertan Çam, Mehmet Akif Özgül, Nilgün Yılmaz Demirci
BACKGROUND AND OBJECTIVES: Selecting the diagnostic procedure for mediastinal restaging after chemotherapy and/or radiotherapy in Stage IIIA-N2 non-small cell lung cancer (NSCLC) patients remains a problem. The aim of the study was to determine the efficacy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the evaluation of mediastinal lymph nodes in the restaging of NSCLC patients. MATERIALS AND METHODS: The present multicentric study retrospectively analyzed the results of Stage IIIA-N2 NSCLC patients who had undergone EBUS for mediastinal restaging after preoperative chemotherapy or radiotherapy or both...
May 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28616904/-the-diagnostic-value-of-endobronchial-ultrasound-guided-needle-aspiration-biopsy-for-lung-or-mediastinal-lymph-node-cancer-and-tuberculosis
#6
Ye Wang, Hui Zhu, Sai Yang, Ke Wang, Pan-Wen Tian, Jing-Yu Shi, Qing-Bing Han, Yong-Xiao Luo, Feng-Min Luo, Wei-Min Li
OBJECTIVES: To determine the value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in diagnosing lung or mediastinal lymph node cancer and tuberculosis. METHODS: Clinical and pathological data of 553 patients who underwent EBUS-TBNA from January 2013 to September 2016 in West China Hospital of Sichuan University were reviewed. The sensitivity, specificity and accuracy of EBUS-TBNA for diagnosing lymph node tumor and tuberculosis of hilar and mediastinal lymph nodes were calculated...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28614224/a-case-report-of-local-treatment-of-inoperable-squamous-cell-lung-carcinoma-with-convex-probe-endobronchial-ultrasound-guided-intratumoral-injection-of-cisplatin-in-a-patient-with-severe-copd
#7
Xiaochen Li, Xiansheng Liu, Xiaoling Rao, Jianping Zhao, Yongjian Xu, Min Xie
RATIONALE: Endobronchial ultrasound as a powerful diagnostic technology can also be used to perform intratumoral chemotherapy for extraluminal tumor. PATIENT CONCERNS: A 69-year-old man with chronic obstructive pulmonary disease (COPD) presented with worsening dyspnea. A pulmonary function test showed severe airway obstruction and that forced expiratory volume in 1 s was 43% of the predicted value after a bronchodilator. DIAGNOSES: A bronchoscopy and histopathological analyses revealed a squamous cell carcinoma mostly located outside of the lumen with central airway obstruction...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28609021/the-critical-role-of-ebus-tbna-cytology-in-the-staging-of-mediastinal-lymph-nodes-in-lung-cancer-patients-a-correlation-study-with-positron-emission-tomography-findings
#8
Mohammed T Lilo, Derek B Allison, Bouchra K Younes, Min Cui, Fred B Askin, Edward Gabrielson, Qing Kay Li
BACKGROUND: The sensitivity and specificity of positron emission tomography (PET) have been significantly improved for the identification of malignancies in recent years; however, it is still necessary to confirm PET findings in a lymph node (LN) by direct tissue sampling. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the most commonly used approach for diagnosing and staging mediastinal LNs, particularly in lung cancer patients with locally advanced disease...
June 13, 2017: Cancer
https://www.readbyqxmd.com/read/28603655/endobronchial-ultrasound-transbronchial-needle-aspiration-for-mediastinal-staging-of-non-small-cell-lung-cancer-variability-of-results-and-perspectives
#9
Elisa Nardecchia, Maria Cattoni, Lorenzo Dominioni
The remarkable value of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) for mediastinal staging of non-small cell lung cancer (NSCLC) is recognized worldwide. Reports from different centers however show considerable variation of EBUS-TBNA performance in terms of diagnostic yield, sensitivity and negative predictive value (NPV). Interpretation of EBUS-TBNA diagnostic efficacy requires clarifying whether the technique is used for purely diagnostic purpose or mediastinal staging, recognizing that different study groups may be inherently heterogeneous and that numerous factors may impact on the procedure outcomes...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603654/ideal-conditions-to-perform-ebus-tbna
#10
Barbara Canneto, Giorgio Ferraroli, Giovanni Falezza, Maurizio Valentino Infante
EBUS-TBNA is gaining widespread acceptance as a minimally invasive procedure for mediastinal staging and re-staging of lung cancer, diagnosis of lung tumors adjacent to large airways and characterization of both malignant and benign lymphadenopathy. The aim of this article is to describe the appropriate setting and practical aspects of the procedure that may help at the start of a new EBUS-TBNA program to improve patient safety, comfort and procedural yield according to operator experience, procedure aim, and institutional needs...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603653/is-bronchodilator-the-correct-treatment-for-copd-subjects-before-ebus
#11
REVIEW
Veronica Leoni, Patrizia Pignatti, Dina Visca, Antonio Spanevello
Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is a reliable and commonly established technique, enabling real-time guidance of transbronchial needle aspiration of mediastinal and hilar structures and parabronchial lung masses. As EBUS-TBNA became more available and adopted by clinicians, questions emerged about the optimal performance of the procedure. Although EBUS is considered safe, there are few complications that could occur during the test, correlated with both the procedure itself and the patient's characteristics...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603652/biopsy-and-re-biopsy-in-lung-cancer-the-oncologist-requests-and-the-role-of-endobronchial-ultrasounds-transbronchial-needle-aspiration
#12
REVIEW
Alessandro Tuzi, Elena Bolzacchini, Matteo B Suter, Alice Giaquinto, Antonio Passaro, Stefania Gobba, Ilaria Vallini, Graziella Pinotti
As the leading cause of death worldwide, lung cancer has proven itself incurable in the advanced stages. For early stages, endobronchial ultrasounds transbronchial needle aspiration (EBUS-TBNA) is now considered the standard to assess mediastinal lymph node, to define the multimodality therapeutic approach. In recent years, EBUS-TBNA has extended its use also in the metastatic and locally recurrent disease. New molecules, with specific mutations that give resistance to current target therapies, have made re-biopsy at disease progression an important assessment, with therapeutic and clinical implication...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603651/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna-from-morphology-to-molecular-testing
#13
REVIEW
Luisella Righi, Francesca Franzi, Francesca Montarolo, Gaia Gatti, Massimo Bongiovanni, Fausto Sessa, Stefano La Rosa
In recent years, endobronchial ultrasound-guided TBNA (EBUS-TBNA) has emerged as an innovative technique for diagnosis and staging of lung cancer and has been successfully introduced into daily clinical practice with several advantages including minimally invasive approach, safe, cost-effective, real time image guidance, broad sampling capability, and rapid on-site evaluation (ROSE). Both cytological and histological approach could be useful to have material for diagnosis, immunohistochemical and molecular analyses which may be very important for targeted therapy with successful rate ranging from 89% to 98%...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603650/in-the-era-of-ultrasound-technology-could-conventional-trans-bronchial-needle-aspiration-still-play-a-role-in-lung-cancer-mediastinal-staging
#14
Alfonso Fiorelli, Carlo Santoriello, Davide Di Natale, Roberto Cascone, Valentina Musella, Rossella Mastromarino, Nicola Serra, Giovanni Vicidomini, Mario Polverino, Mario Santini
BACKGROUND: To evaluate the feasibility of a combined strategy including conventional-trans-bronchial needle aspiration biopsy (C-TBNA) and endobronchial ultrasounds transbronchial needle aspiration (EBUS-TBNA) for sampling mediastinal adenopathies in patients with lung cancer in order to determinate whether in the era of ultrasound technology C-TBNA could still play a role in mediastinal staging. METHODS: It was a retrospective multicenter study including all consecutive patients with lung cancer and radiological mediastinal adenopathies undergoing TBNA for mediastinal staging (January 2014 - July 2016)...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603649/comparison-of-multiple-techniques-for-endobronchial-ultrasound-transbronchial-needle-aspiration-specimen-preparation-in-a-single-institution-experience
#15
Nicola Rotolo, Maria Cattoni, Giorgio Crosta, Elisa Nardecchia, Albino Poli, Francesca Moretti, Valentina Conti, Stefano La Rosa, Lorenzo Dominioni, Andrea Imperatori
BACKGROUND: The optimal method for specimen preparation of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) is still controversial. This study aims to compare several techniques available for EBUS-TBNA specimen acquisition and processing, in order to identify the best performing technique. METHODS: We retrospectively reviewed the data of 199 consecutive patients [male, 73%; median age, 64 years (IQR: 52-74 years)] undergoing EBUS-TBNA at our institution from 2012 through 2014 for diagnosis of hilar-mediastinal lymph node enlargement suspect of neoplastic (n=139) or granulomatous (n=60) disease...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603648/color-doppler-sonography-patterns-in-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-of-mediastinal-lymph-nodes
#16
Mario Nosotti, Alessandro Palleschi, Davide Tosi, Paolo Mendogni, Ilaria Righi, Rosaria Carrinola, Lorenzo Rosso
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is commonly used for the pathological diagnosis in patients with mediastinal lymphadenopathy. Even though the accuracy of EBUS-TBNA is considered high, several authors have tried to outline characteristic ultrasound criteria for malignant mediastinal lymph-node identification to maximize this accuracy. Recently, a color-Doppler patterns classification has been proposed by Nakajima to target suspected mediastinal lymph-nodes...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603647/multicentric-study-of-endobronchial-ultrasound-transbronchial-needle-aspiration-for-lung-cancer-staging-in-italy
#17
Nicola Rotolo, Andrea Imperatori, Mario Nosotti, Luigi Santambrogio, Alessandro Palleschi, Lorenzo Dominioni, Giorgio Crosta, Pierfranco Foccoli, Gianluca Pariscenti, Eliseo Passera, Luigi Bortolotti, Giovanni Falezza, Maurizio Infante, Elisa Daffrè, Maria Cattoni, Lorenzo Rosso
BACKGROUND: Multi-institutional studies of endobronchial-ultrasound transbronchial needle aspiration (EBUS-TBNA) for mediastinal staging in lung cancer are scarce. It is unclear if the high diagnostic performance of EBUS-TBNA reported by experts' guidelines can be generally achieved. METHODS: This is a retrospective study performed in five tertiary referral centers of thoracic surgery in Italy, to assess the EBUS-TBNA diagnostic performance in patients with non-small cell lung cancer (NSCLC)...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603646/ten-year-experience-with-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-single-center-results-in-mediastinal-diagnostic-and-staging
#18
Lorenzo Rosso, Stefano Ferrero, Paolo Mendogni, Eleonora Bonaparte, Rosaria Carrinola, Alessandro Palleschi, Ilaria Righi, Matteo Montoli, Francesco Damarco, Davide Tosi
BACKGROUND: Endobronchial ultrasonography with transbronchial needle aspiration (EBUS-TBNA) is recognized as an accurate and minimal invasive procedure for diagnosis and staging of lung cancer and lymph nodal malignancies. EBUS is recommended as the first choice procedure for mediastinal staging in lung cancer in international guidelines. METHODS: A retrospective evaluation was performed on single center experience with EBUS-TBNA in our thoracic surgery department in a 10-year time frame...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28603645/understanding-local-performance-data-for-ebus-tbna-insights-from-an-unselected-case-series-at-a-high-volume-uk-center
#19
Vandana Jeebun, Richard Neil Harrison
BACKGROUND: We reviewed the diagnostic performance of endobronchial ultrasound transbronchial aspiration (EBUS-TBNA) on an unselected large cohort of patients who underwent the procedure in our institution in the past 3 years and to compare against published standards and existing literature. METHODS: All consecutive patients who underwent EBUS from January 2013 to December 2015 were included in the retrospective analysis, with a minimum of 6 months of clinico-radiological follow up...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28592025/-comparison-of-two-quantitative-methods-of-endobronchial-ultrasound-real-time-elastography-for-evaluating-intrathoracic-lymph-nodes
#20
X W Mao, J Y Yang, X X Zheng, L Wang, L Zhu, Y Li, H K Xiong, J Y Sun
Objective: To compare the clinical value of two quantitative methods in analyzing endobronchial ultrasound real-time elastography (EBUS-RTE) images for evaluating intrathoracic lymph nodes. Methods: From January 2014 to April 2014, EBUS-RTE examination was performed in patients who received EBUS-TBNA examination in Shanghai Chest Hospital. Each intrathoracic lymph node had a selected EBUS-RTE image. Stiff area ratio and mean hue value of region of interest (ROI) in each image were calculated respectively. The final diagnosis of lymph node was based on the pathologic/microbiologic results of EBUS-TBNA, pathologic/microbiologic results of other examinations and clinical following-up...
June 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
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