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https://www.readbyqxmd.com/read/28066671/current-advances-of-endobronchial-ultrasonography-in-the-diagnosis-and-staging-of-lung-cancer
#1
REVIEW
Chao-Chi Ho, Ching-Kai Lin, Ching-Yao Yang, Lih-Yu Chang, Shu-Yung Lin, Chong-Jen Yu
The diagnosis and staging of patients with lung cancer has relied on tissue sampling. Endobronchial ultrasound (EBUS) is a minimally invasive procedure for the rapid and safe acquisition of tissue and can be done easily and repeatedly. EBUS transbronchial needle aspiration (TBNA) is now the standard for diagnosis of mediastinal and hilar lymphadenopathy and should be considered in patients who have a high probability of lymph node metastases without systemic involvement. EBUS also provides guidance for biopsy of peripheral lung lesions...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28066614/the-role-of-bronchoscopy-in-the-diagnosis-of-early-lung-cancer-a-review
#2
REVIEW
Marco Andolfi, Rossella Potenza, Rosanna Capozzi, Valeria Liparulo, Francesco Puma, Kazuhiro Yasufuku
Lung cancer is the leading cause of cancer-related deaths worldwide with an overall 5-year survival rate of 17% after diagnoses. Indeed many patients tend to have a very poor prognosis, due to being diagnosed at an advanced stage. Conversely patients who are diagnosed at an early stage have a 5-year survival >70%, indicating that early detection of lung cancer is crucial to improve survival. Although flexible bronchoscopy is a relatively non-invasive procedure for patients suspected of having lung cancer, only 29% of carcinoma in situ (CIS) and 69% of microinvasive tumors were detectable using white light bronchoscopy (WLB) alone...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28054531/diagnostic-value-of-core-biopsy-histology-and-cytology-sampling-of-mediastinal-lymph-nodes-using-21-gauge-ebus-tbna-needle
#3
Preyas J Vaidya, Avinandan Saha, Arvind H Kate, Kamlesh Pandey, Vinod B Chavhan, Joerg D Leuppi, Prashant N Chhajed
INTRODUCTION: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the initial modality of choice in sampling mediastinal lymphadenopathy. It is possible to obtain both cytological and histological samples using both 21-gauge and 22-gauge EBUS-TBNA needles. The current study was undertaken to compare the diagnostic yield of cytology and histology samples obtained by the same EBUS-TBNA 21-gauge needle. PATIENTS AND METHODS: One hundred sixty-six consecutive patients who underwent EBUS-TBNA with a 21-gauge EBUS-TBNA needle over a period of 3 years were included in this retrospective analysis...
July 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28052172/role-of-transbronchial-needle-aspiration-conventional-and-ebus-guided-in-the-diagnosis-of-histoplasmosis-in-patients-presenting-with-mediastinal-lymphadenopathy
#4
Amik Sodhi, Rodjawan Supakul, George W Williams, Elizabeth A Tolley, Arthur S Headley, Luis C Murillo, Dipen Kadaria
OBJECTIVES: The superior performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis and staging of malignancy has been demonstrated, with some investigators suggesting the same for sarcoidosis. The role of EBUS-TBNA in the diagnosis of histoplasmosis is not clear, however. In this study we estimate the diagnostic yield of conventional TBNA (cTBNA) and EBUS-TBNA for the diagnosis of histoplasmosis in patients with mediastinal lymphadenopathy...
January 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28051017/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-increases-the-yield-of-transbronchial-lung-biopsy-for-the-evaluation-of-peribronchial-lesions
#5
Cheng Chen, Chuan-Yong Mu, Mei-Qin Su, Jing-Yu Mao, Ye-Han Zhu, Jian-An Huang
BACKGROUND: Due to absence of visible endobronchial target, the diagnostic yield of flexible bronchoscopy for peribronchial lesions has been unsatisfactory. Convex probe endobronchial ultrasound (CP-EBUS) has allowed for performing real-time transbronchial needle aspiration (TBNA) of enlarged hilar and mediastinal lymph nodes and therefore could also be used as a means of diagnosing proximal peribronchial lesions. METHODS: We retrospectively analyzed the results related to 72 patients who underwent CP-EBUS for peribronchial lesions without endobronchial involvement and adjacent to three-grade bronchi based on chest computed tomography (CT) scan...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28027732/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-the-nodal-staging-of-stereotactic-ablative-body%C3%A2-radiotherapy-patients
#6
Macarena R Vial, Kashif A Khan, Oisin O'Connell, S Andrew Peng, Daniel R Gomez, Joe Y Chang, David C Rice, Reza Mehran, Carlos J Jimenez, Horiana B Grosu, David E Ost, George A Eapen
BACKGROUND: Patients with non-small cell lung cancer (NSCLC) being evaluated for stereotactic ablative body radiotherapy (SABR) are typically staged noninvasively with positron emission tomography/computed tomography (PET/CT). Incorporating endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) into the staging workup of these patients has not been evaluated. Our primary objective was to compare the performance of PET/CT with EBUS-TBNA for intrathoracic nodal assessment among SABR-eligible patients...
December 24, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28018536/computer-modeling-to-evaluate-the-impact-of-technology-changes-on-resident-procedural-volume
#7
Tyler R Grenda, Tiffany N S Ballard, Andrea T Obi, William Pozehl, F Jacob Seagull, Ryan Chen, Amy M Cohn, Mark S Daskin, Rishindra M Reddy
BACKGROUND : As resident "index" procedures change in volume due to advances in technology or reliance on simulation, it may be difficult to ensure trainees meet case requirements. Training programs are in need of metrics to determine how many residents their institutional volume can support. OBJECTIVE : As a case study of how such metrics can be applied, we evaluated a case distribution simulation model to examine program-level mediastinoscopy and endobronchial ultrasound (EBUS) volumes needed to train thoracic surgery residents...
December 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28007409/sensitivity-of-cytology-specimens-from-bronchial-aspirate-or-washing-during-bronchoscopy-in-the-diagnosis-of-lung-malignancies-an-update
#8
Philippe Girard, Raffaele Caliandro, Agathe Seguin-Givelet, Stéphane Lenoir, Dominique Gossot, Pierre Validire, Jean-Baptiste Stern
BACKGROUND: Routine collection of cytology specimens from bronchial aspirate or washing is thought to increase the sensitivity of bronchoscopy for diagnosing malignant lung lesions. However, the added value of this practice has not been reappraised in a context of changing epidemiology. PATIENTS AND METHODS: In a retrospective monocenter study, all cytology specimens from bronchial aspirate or washing collected between May 2011 and December 2014 and the corresponding patients' files were reviewed...
November 21, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28005836/pulmonologist-performed-per-esophageal-needle-aspiration-of-parenchymal-lung-lesions-using-an-ebus-bronchoscope-diagnostic-utility-and-safety
#9
Daniel P Steinfort, Michael W Farmer, Louis B Irving, Barton R Jennings
BACKGROUND: Transesophageal introduction of the endobronchial ultrasound (EBUS) videobronchoscope allows pulmonologists to perform endoscopic ultrasound fine-needle aspiration (EUS-B-FNA) of mediastinal lesions. Safety, diagnostic accuracy, and feasibility of EUS-B-FNA in evaluation of pulmonary parenchymal lesions are not established. METHODS: All patients undergoing pulmonologist-performed EUS-B-FNA of parenchymal lung lesions at 2 tertiary centers were included in this prospective observational cohort study...
December 21, 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28002683/a-prediction-model-to-help-with-the-assessment-of-adenopathy-in-lung-cancer-hal
#10
Oisin J O'Connell, Francisco A Almeida, Michael J Simoff, Lonny Yarmus, Ray Lazarus, Benjamin Young, Yu Chen, Roy Semaan, Timothy M Saettele, Joseph Cicenia, Harmeet Bedi, Corrine Kliment, Liang Li, Sonali Sethi, Javier Diaz-Mendoza, David Feller-Kopman, Juhee Song, Thomas Gildea, Hans Lee, Horiana B Grosu, Michael Machuzak, Macarena Rodriguez-Vial, George A Eapen, Carlos A Jimenez, Roberto F Casal, David E Ost
RATIONALE: Estimating the probability of finding N2 or N3 (prN2/3) malignant nodal disease on EBUS-TBNA in patients with non-small cell lung cancer (NSCLC) can facilitate the selection of subsequent management strategies. OBJECTIVE: The goal of this study was to develop a clinical prediction model for estimating the prN2/3. METHODS: We used the AQuIRE registry to identify patients with NSCLC with clinical radiographic stage T1-3, N0-3, M0 disease that had EBUS-TBNA for staging...
December 21, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27984385/conventional-transbronchial-needle-aspiration-versus-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-with-or-without-rapid-on-site-evaluation-for-the-diagnosis-of-sarcoidosis-a-randomized-controlled-trial
#11
Karan Madan, Ashesh Dhungana, Anant Mohan, Vijay Hadda, Deepali Jain, Sudheer Arava, Ravindra M Pandey, Gopi C Khilnani, Randeep Guleria
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) as a standalone modality is superior to conventional TBNA (c-TBNA) for the diagnosis of sarcoidosis. However, the overall yield is not different if combined with endobronchial biopsy (EBB) and transbronchial lung biopsy (TBLB). The utility of rapid on-site evaluation (ROSE) in a comparative evaluation of EBUS-TBNA versus c-TBNA for the diagnosis of sarcoidosis has not been previously evaluated. METHODS: Eighty patients with suspected sarcoidosis were randomized 1:1:1:1 into 4 groups: c-TBNA without ROSE (TBNA-NR), c-TBNA with ROSE (TBNA-R), EBUS-TBNA without ROSE (EBUS-NR), and EBUS-TBNA with ROSE (EBUS-R)...
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27984382/diagnostic-yield-and-complications-of-ebus-tbna-performed-under-bronchoscopist-directed-conscious-sedation-single-center-experience-of-1004-subjects
#12
Sahajal Dhooria, Inderpaul S Sehgal, Nalini Gupta, Ashutosh N Aggarwal, Digambar Behera, Ritesh Agarwal
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) can be performed under either conscious sedation or general anesthesia. Herein, we describe the diagnostic yield and complications of EBUS-TBNA performed under bronchoscopist-directed conscious sedation. METHODS: This is a retrospective analysis of data collected in the bronchoscopy suite of this center on EBUS-TBNA or endoscopic ultrasound with a bronchoscope-guided fine needle aspiration (EUS-B-FNA) procedures performed between July 2011 and January 2016...
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27984381/bronchoscopist-guided-sedation-in-ebus-tbna-can-the-pitcher-also-be-a-hitter
#13
Preyas J Vaidya, Prashant N Chhajed
No abstract text is available yet for this article.
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27977603/diagnostic-performance-of-convex-probe-ebus-tbna-in-patients-with-mediastinal-and-coexistent-endobronchial-or-peripheral-lesions
#14
Akash Verma, Kee San Goh, Chee Kiang Phua, Wen Yuan Sim, Kuan Sen Tee, Albert Y H Lim, Dessmon Y H Tai, Soon Keng Goh, Ai Ching Kor, Benjamin Ho, Sennen J W Lew, John Abisheganaden
To compare the performance of convex probe endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) with conventional endobronchial biopsy (EBB) or transbronchial lung biopsy (TBLB) in patients with mediastinal, and coexisting endobronchial or peripheral lesions.Retrospective review of records of patients undergoing diagnostic EBUS-TBNA and conventional bronchoscopy in 2014.A total of 74 patients had mediastinal, and coexisting endobronchial or peripheral lesions. The detection rate of EBUS-TBNA for mediastinal lesion >1 cm in short axis, EBB for visible exophytic type of endobronchial lesion, and TBLB for peripheral lesion with bronchus sign were 71%, 75%, and 86%, respectively...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27965902/tuberculosis-and-migration-a-challenge-for-medical-staff-and-public-health
#15
Ines Griesshammer, David Shiva Srivastava, Christophe von Garnier, Till Silvan Blaser, Aris Exadaktylos, Moritz Steib
A high number of asylum seekers enter Switzerland every year. They often originate from countries with a high TB prevalence. Our patient from Somalia presented with 2 lipoma-like tumors with pain on palpation on his left chest wall but no symptoms including coughing, fever, night-sweats, or loss of weight. CT scan then showed diffuse infiltrations of his lung and multiple abscesses on his left chest wall. Therefore contagious tuberculosis (TB) was suspected and the patient was put in isolation. In the follow-up the diagnosis of open TB was proofed with bronchial secretion and EBUS-guided biopsy that showed acid-fast rods...
2016: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/27942415/lung-cancer-a-rare-indication-for-but-frequent-complication-after-lung-transplantation
#16
REVIEW
Dirk Van Raemdonck, Robin Vos, Jonas Yserbyt, Herbert Decaluwe, Paul De Leyn, Geert M Verleden
Lung transplantation is an effective and safe therapy for carefully selected patients suffering from a variety of end-stage pulmonary diseases. Lung cancer negatively affects prognosis, particularly in patients who are no longer candidates for complete resection. Lung transplantation can be considered for carefully selected and well staged lung cancer patients with proven, lung-limited, multifocal, (minimally invasive) adenocarcinoma in situ (AIS) (previously called bronchioloalveolar cell carcinoma) causing respiratory failure...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27931198/fdg-pet-parameters-predicting-mediastinal-malignancy-in-lung-cancer
#17
M Serra Fortuny, M Gallego, Ll Berna, C Montón, L Vigil, M J Masdeu, A Fernández-Villar, M I Botana, R Cordovilla, R García-Luján, E Cases, E Monsó
BACKGROUND: Staging of mediastinal lymph nodes in non-small cell lung cancer (NSCLC) is mandatory. The maximum Standard Uptake Value (SUVmax) obtained using F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is the best non-invasive technique available for this evaluation, but its performance varies from center to center. The aim of the present study was to identify FDG-PET predictors of mediastinal malignancy that are able to minimize intercenter variability and improve the selection of subsequent staging procedures...
December 8, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27916244/first-evaluation-of-the-new-thin-convex-probe-endobronchial-ultrasound-scope-a-human-ex%C3%A2-vivo-lung-study
#18
Priya Patel, Hironobu Wada, Hsin-Pei Hu, Kentaro Hirohashi, Tatsuya Kato, Hideki Ujiie, Jin Young Ahn, Daiyoon Lee, William Geddie, Kazuhiro Yasufuku
BACKGROUND: Endobronchial ultrasonography (EBUS)-guided transbronchial needle aspiration allows for sampling of mediastinal lymph nodes. The external diameter, rigidity, and angulation of the convex probe EBUS renders limited accessibility. This study compares the accessibility and transbronchial needle aspiration capability of the prototype thin convex probe EBUS against the convex probe EBUS in human ex vivo lungs rejected for transplant. METHODS: The prototype thin convex probe EBUS (BF-Y0055; Olympus, Tokyo, Japan) with a thinner tip (5...
December 1, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27902883/metastatic-carotid-body-paraganglioma-of-lungs-and-lymph-nodes-unsuspected-diagnosis-on-ebus-tbna
#19
Kalpana Kumari, Deepali Jain, Rohit Kumar, Anant Mohan, Rakesh Kumar
Paragangliomas are tumors that originate from the extra-adrenal chromaffin and nonchromaffin cells of neural crest origin. Lymph node metastases are common, while distant metastases to lung, liver, and bone are rare events and usually occur in the presence of a long standing clinically evident primary tumor. Primary diagnosis of paraganglioma at a metastatic site without a known primary is a diagnostic challenge. We report a case of an adult woman with incidentally detected metastasis to bilateral lungs from an occult carotid body paraganglioma, which presented a cytopathological diagnostic dilemma on EBUS-TBNA from paratracheal lymph nodes...
November 30, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27894283/small-lung-lesions-invisible-under-fluoroscopy-are-located-accurately-by-three-dimensional-localization-technique-on-chest-wall-surface-and-performed-bronchoscopy-procedures-to-increase-diagnostic-yields
#20
Chaosheng Deng, Xiaoming Cao, Dawen Wu, Haibo Ding, Ruixiong You, Qunlin Chen, Linying Chen, Xin Zhang, Qiaoxian Zhang, Yongquan Wu
BACKGROUND: Nowadays, small peripheral pulmonary lesions (PPLs) are frequently detected and the prognosis of lung cancer depends on the early diagnosis. Because of the high fee and requiring specialized training, many advanced techniques are not available in many developing countries and rural districts. METHODS: Three sets of opaque soft copper wires visible under the fluoroscopy (Flu) in the Flu-flexible bronchoscopy (FB) group (n = 24), which determined the three planes of the lesion, were respectively placed firmly on the surface of the chest wall with adhesive tape on the chest wall...
November 29, 2016: BMC Pulmonary Medicine
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