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https://www.readbyqxmd.com/read/28238364/design-and-performance-of-subgrade-biogeochemical-reactors
#1
Jeff Gamlin, Doug Downey, Brad Shearer, Paul Favara
Subgrade biogeochemical reactors (SBGRs), also commonly referred to as in situ bioreactors, are a unique technology for treatment of contaminant source areas and groundwater plume hot spots. SBGRs have most commonly been configured for enhanced reductive dechlorination (ERD) applications for chlorinated solvent treatment. However, they have also been designed for other contaminant classes using alternative treatment media. The SBGR technology typically consists of removal of contaminated soil via excavation or large-diameter augers, and backfill of the soil void with gravel and treatment amendments tailored to the target contaminant(s)...
February 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28238114/modifying-the-autism-spectrum-rating-scale-6-18%C3%A2-years-to-a-chinese-context-an-exploratory-factor-analysis
#2
Hao Zhou, Lili Zhang, Xuerong Luo, Lijie Wu, Xiaobing Zou, Kun Xia, Yimin Wang, Xiu Xu, Xiaoling Ge, Yong-Hui Jiang, Eric Fombonne, Weili Yan, Yi Wang
The purpose of this study was to explore the psychometric properties of the Chinese version of the autism spectrum rating scale (ASRS). We recruited 1,625 community-based children and 211 autism spectrum disorder (ASD) cases from 4 sites, and the parents of all participants completed the Chinese version of the ASRS. A robust weighted least squares means and variance adjusted estimator was used for exploratory factor analysis. The 3-factor structure included 59 items suitable for the current sample. The item reliability for the modified Chinese version of the ASRS (MC-ASRS) was excellent...
February 25, 2017: Neuroscience Bulletin
https://www.readbyqxmd.com/read/28237072/effect-of-immobilization-of-metacarpophalangeal-joint-in-thumb-carpometacarpal-osteoarthritis-on-pain-and-function-a-quasi-experimental-trial
#3
Raquel Cantero-Téllez, Jorge Hugo Villafañe, Kristin Valdes, Pedro Berjano
STUDY DESIGN: A quasi-experimental trial. INTRODUCTION: Orthoses are effective to decrease pain and improve function in patients with carpometacarpal osteoarthritis (CMC OA). However, current research does not support one design of an orthosis as more effective and/or more favorable than another. PURPOSE OF THE STUDY: The aim of this study was to compare the effectiveness of 2 different static orthosis on pain and functional abilities on CMC OA...
February 22, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28236986/-inclusion-criteria-and-rating-scales-for-rcts-in-psychiatry-the-future-of-qualitative-studies
#4
D Pringuey, R Pommier, F Pringuey-Criou, S Boyer, C Massoubre, E Fakra, M Adida, R Belzeaux, T Bottai, J-M Azorin
An inventory on the two critical dimensions that structure the Randomized Controlled Trial in Psychiatry, namely the definition of inclusion criteria for eligible patients for testing and the choice of psychometric methods of pathology assessment and its evolution during the experiment, considers the importance of increasingly numerous and precise international recommendations. Taking into account the formal constraints of industrial, questioning the cultural differences of the methodological approach of the tests, meeting the requirements of feasibility and ever increasing security, frequent cumbersome procedure often contrasts with the modest nature of the results...
December 2016: L'Encéphale
https://www.readbyqxmd.com/read/28236266/the-cancer-loneliness-scale-and-cancer-related-negative-social-expectations-scale-development-and-validation
#5
Rebecca N Adams, Catherine E Mosher, Kevin L Rand, Adam T Hirsh, Patrick O Monahan, Rafat Abonour, Kurt Kroenke
PURPOSE: Loneliness is a known risk factor for poor mental and physical health outcomes and quality of life in the general population, and preliminary research suggests that loneliness is linked to poorer health outcomes in cancer patients as well. Various aspects of the cancer experience contribute to patients feeling alone and misunderstood. Furthermore, loneliness theory suggests that negative social expectations, which may specifically relate to the cancer experience, precipitate and sustain loneliness...
February 24, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28235400/implementation-of-cardiovascular-disease-prevention-in-primary-health-care-enhancing-understanding-using-normalisation-process-theory
#6
Nerida Volker, Lauren T Williams, Rachel C Davey, Thomas Cochrane, Tanya Clancy
BACKGROUND: The reorientation of primary health care towards prevention is fundamental to addressing the rising burden of chronic disease. However, in Australia, cardiovascular disease prevention practice in primary health care is not generally consistent with existing guidelines. The Model for Prevention study was a whole-of-system cardiovascular disease prevention intervention, with one component being enhanced lifestyle modification support and addition of a health coaching service in the general practice setting...
February 24, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28231632/reliability-and-validity-of-the-chinese-version-of-the-self-care-ability-scale-for-the-elderly
#7
Han Gao, Ulrika Söderhamn, Christina Cliffordson, Lina Guo, Qiyun Guo, Kun Liu
AIMS AND OBJECTIVES: To translate the Self-care Ability Scale for the Elderly into Simplified Chinese, and to test the Chinese version of the scale regarding its reliability and validity among older people. BACKGROUND: Self-care is an important topic in nursing. When assessing older people's self-care ability, it is essential that a reliable and valid instrument is used. DESIGN: This study employed across-sectional design. METHODS: We translated the English version of the Self-care Ability Scale for the Elderly into Simplified Chinese according to Brislin's translation guidelines, and carried out a questionnaire survey among 610 older people, including both community-dwelling people and hospital patients, in Jinzhou City, People's Republic of China...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231285/the-mother-s-autonomy-in-decision-making-madm-scale-patient-led-development-and-psychometric-testing-of-a-new-instrument-to-evaluate-experience-of-maternity-care
#8
Saraswathi Vedam, Kathrin Stoll, Kelsey Martin, Nicholas Rubashkin, Sarah Partridge, Dana Thordarson, Ganga Jolicoeur
OBJECTIVE: To develop and validate a new instrument that assesses women's autonomy and role in decision making during maternity care. DESIGN: Through a community-based participatory research process, service users designed, content validated, and administered a cross-sectional quantitative survey, including 31 items on the experience of decision-making. SETTING AND PARTICIPANTS: Pregnancy experiences (n = 2514) were reported by 1672 women who saw a single type of primary maternity care provider in British Columbia...
2017: PloS One
https://www.readbyqxmd.com/read/28230410/a-self-report-measure-for-the-icd-11-dimensional-trait-model-proposal-the-personality-inventory-for-icd-11
#9
Joshua R Oltmanns, Thomas A Widiger
Proposed for the 11th edition of the World Health Organization's International Classification of Diseases (ICD-11) is a dimensional trait model for the classification of personality disorder (Tyrer, Reed, & Crawford, 2015). The ICD-11 proposal consists of 5 broad domains: negative affective, detachment, dissocial, disinhibition, and anankastic (Mulder, Horwood, Tyrer, Carter, & Joyce, 2016). Several field trials have examined this proposal, yet none has included a direct measure of the trait model. The purpose of the current study was to develop and provide initial validation for the Personality Inventory for ICD-11 (PiCD), a self-report measure of this proposed 5-domain maladaptive trait model...
February 23, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28230408/psychometric-properties-of-adolescent-time-inventory-time-attitude-ati-ta-scores-in-three-waves-of-longitudinal-data
#10
Frank C Worrell, Michael T McKay, James R Andretta
Within the broad area of time perspective, there are numerous narrower or more specific constructs. One of these, time attitudes, is said to refer to an individual's emotional and evaluative feelings toward the past, the present, and the future. Scores on the Adolescent Time Inventory-Time Attitudes Scale (ATI-TA) have been shown to be psychometrically sound in a range of cross-sectional studies in different cultural contexts. The present study is the first longitudinal (3 waves) examination of these scores...
February 23, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28230154/compiler-aided-systematic-construction-of-large-scale-dna-strand-displacement-circuits-using-unpurified-components
#11
Anupama J Thubagere, Chris Thachuk, Joseph Berleant, Robert F Johnson, Diana A Ardelean, Kevin M Cherry, Lulu Qian
Biochemical circuits made of rationally designed DNA molecules are proofs of concept for embedding control within complex molecular environments. They hold promise for transforming the current technologies in chemistry, biology, medicine and material science by introducing programmable and responsive behaviour to diverse molecular systems. As the transformative power of a technology depends on its accessibility, two main challenges are an automated design process and simple experimental procedures. Here we demonstrate the use of circuit design software, combined with the use of unpurified strands and simplified experimental procedures, for creating a complex DNA strand displacement circuit that consists of 78 distinct species...
February 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28230065/in-vivo-evaluation-of-a-novel-format-of-a-bivalent-her3-targeting-and-albumin-binding-therapeutic-affibody-construct
#12
Tarek Z Bass, Maria Rosestedt, Bogdan Mitran, Fredrik Y Frejd, John Löfblom, Vladimir Tolmachev, Stefan Ståhl, Anna Orlova
Overexpression of human epidermal growth factor receptor 3 (HER3) is involved in resistance to several therapies for malignant tumours. Currently, several anti-HER3 monoclonal antibodies are under clinical development. We introduce an alternative approach to HER3-targeted therapy based on engineered scaffold proteins, i.e. affibody molecules. We designed a small construct (22.5 kDa, denoted 3A3), consisting of two high-affinity anti-HER3 affibody molecules flanking an albumin-binding domain ABD, which was introduced for prolonged residence in circulation...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229144/construction-of-leaf-like-cuo-cu2o-nanocomposites-on-copper-foam-for-high-performance-supercapacitors
#13
Dong He, Guanda Wang, Guolong Liu, Hui Suo, Chun Zhao
Leaf-like CuO-Cu2O nanosheets have been prepared on copper foam by a one-step simple anodization method, which can be used as an advanced binder-free supercapacitor electrode. The performance of the CuO-Cu2O/Cu foam electrode was optimized through controlling and restraining the current density and reaction time. The prepared electrode exhibits a very high specific capacitance (1.954 F cm(-2) at a scan rate of 2 mV s(-1)), excellent durability (120% retention after 5000 cycles), remarkable rate capability (91...
February 23, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28228091/exploring-the-transcriptome-of-non-model-oleaginous-microalga-dunaliella-tertiolecta-through-high-throughput-sequencing-and-high-performance-computing
#14
Lina Yao, Kenneth Wei Min Tan, Tin Wee Tan, Yuan Kun Lee
BACKGROUND: RNA-Seq technology has received a lot of attention in recent years for microalgal global transcriptomic profiling. It is widely used in transcriptome-wide analysis of gene expression., particularly for microalgal strains with potential as biofuel sources. However, insufficient genomic or transcriptomic information of non-model microalgae has limited the understanding of their regulatory mechanisms and hampered genetic manipulation to enhance biofuel production. As such, an optimal microalgal transcriptomic database construction is a subject of urgent investigation...
February 22, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28227867/knife-edge-scanning-microscopy-for-in-silico-study-of-cerebral-blood-flow-from-biological-imaging-data-to-flow-simulations
#15
Michael R Nowak, Alexander Lozovskiy, Dimitri Dobroskok, Yoonsuck Choe, Michael R Nowak, Alexander Lozovskiy, Dimitri Dobroskok, Yoonsuck Choe, Dimitri Dobroskok, Michael R Nowak, Alexander Lozovskiy, Yoonsuck Choe
Knife-edge scanning microscopy provides the capability to image whole-brain cerebral microvasculature of small organisms, such as mice, at sub-micron resolution, providing a feasible foundation for the reconstruction of circulatory pathways from the systemic to cellular scale. In this paper, we illustrate the feasibility of using this data to model cerebral blood flow using numerical simulations. Starting with a small vascular element in microcirculation of interest, we present its segmentation from the imaging-data volume, construction of its triangular surface mesh, assembly of its tetrahedral volumetric mesh from the surface, and then conclude with Stokes flow simulation of plasma through the microvascular vessel...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227594/fall-risk-factors-analysis-based-on-sample-entropy-of-plantar-kinematic-signal-during-stance-phase
#16
Shengyun Liang, Huiyu Jia, Zilong Li, Huiqi Li, Xing Gao, Zuchang Ma, Yingnan Ma, Guoru Zhao, Shengyun Liang, Huiyu Jia, Zilong Li, Huiqi Li, Xing Gao, Zuchang Ma, Yingnan Ma, Guoru Zhao, Shengyun Liang, Huiqi Li, Huiyu Jia, Xing Gao, Zuchang Ma, Guoru Zhao, Yingnan Ma, Zilong Li
Falls are a multi-causal phenomenon with a complex interaction. The aim of our research is to study the effect of multiple variables for potential risk of falls and construct an elderly fall risk assessment model based on demographics data and gait characteristics. A total of 101 subjects, whom belong to Malianwa Street, aged above 50 years old and participated in questionnaire survey. Participants were classified into three groups (high, medium and low risk group) according to the score of elderly fall risk assessment scale...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227106/epileptic-seizure-onset-correlates-with-long-term-eeg-functional-brain-network-properties
#17
Maria Anastasiadou, Avgis Hadjipapas, Manolis Christodoulakis, Eleftherios S Papathanasiou, Savvas S Papacostas, Georgios D Mitsis, Maria Anastasiadou, Avgis Hadjipapas, Manolis Christodoulakis, Eleftherios S Papathanasiou, Savvas S Papacostas, Georgios D Mitsis, Maria Anastasiadou, Avgis Hadjipapas, Manolis Christodoulakis, Savvas S Papacostas, Eleftherios S Papathanasiou, Georgios D Mitsis
We investigated the correlation of epileptic seizure onset times with long term EEG functional brain network properties. To do so, we constructed binary functional brain networks from long-term, multichannel electroencephalographic data recorded from nine patients with epilepsy. The corresponding network properties were quantified using the average network degree. It was found that the network degree (as well as other network properties such as the network efficiency and clustering coefficient) exhibited large fluctuations over time; however, it also exhibited specific periodic temporal structure over different time scales (1...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227099/a-large-scale-detailed-neuronal-model-of-electrical-stimulation-of-the-dentate-gyrus-and-perforant-path-as-a-platform-for-electrode-design-and-optimization
#18
Clayton S Bingham, Kyle Loizos, Gene Yu, Andrew Gilbert, Jean-Marie Bouteiller, Dong Song, Gianluca Lazzi, Theodore W Berger, Clayton S Bingham, Kyle Loizos, Gene Yu, Andrew Gilbert, Jean-Marie Bouteiller, Dong Song, Gianluca Lazzi, Theodore W Berger, Kyle Loizos, Gene Yu, Theodore W Berger, Gianluca Lazzi, Jean-Marie Bouteiller, Clayton S Bingham, Dong Song, Andrew Gilbert
Owing to the dramatic rise in treatment of neurological disorders with electrical micro-stimulation it has become apparent that the major technological limitation in deploying effective devices lies in the process of designing efficient, safe, and outcome specific electrode arrays. The time-consuming and low-fidelity nature of gathering test data using experimental means and the immense control and flexibility of computational models, has prompted us and others to build models of electrical stimulation of neural networks that can be simulated in a computer...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226770/a-multiscale-model-based-analysis-of-the-multi-tissue-interplay-underlying-blood-glucose-regulation-in-type-i-diabetes
#19
Federico Wadehn, Stephan Schaller, Thomas Eissing, Markus Krauss, Lars Kupfer, Federico Wadehn, Stephan Schaller, Thomas Eissing, Markus Krauss, Lars Kupfer, Federico Wadehn, Markus Krauss, Lars Kupfer, Stephan Schaller, Thomas Eissing
A multiscale model for blood glucose regulation in diabetes type I patients is constructed by integrating detailed metabolic network models for fat, liver and muscle cells into a whole body physiologically-based pharmacokinetic/pharmacodynamic (pBPK/PD) model. The blood glucose regulation PBPK/PD model simulates the distribution and metabolization of glucose, insulin and glucagon on an organ and whole body level. The genome-scale metabolic networks in contrast describe intracellular reactions. The developed multiscale model is fitted to insulin, glucagon and glucose measurements of a 48h clinical trial featuring 6 subjects and is subsequently used to simulate (in silico) the influence of geneknockouts and drug-induced enzyme inhibitions on whole body blood glucose levels...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226578/automatic-prostate-segmentation-on-mr-images-with-deep-network-and-graph-model
#20
Ke Yan, Changyang Li, Xiuying Wang, Ang Li, Yuchen Yuan, Dagan Feng, Mohamed Khadra, Jinman Kim, Ke Yan, Changyang Li, Xiuying Wang, Ang Li, Yuchen Yuan, Dagan Feng, Mohamed Khadra, Jinman Kim, Ke Yan, Ang Li, Yuchen Yuan, Xiuying Wang, Jinman Kim, Dagan Feng, Changyang Li, Mohamed Khadra
Automated prostate diagnoses and treatments have gained much attention due to the high mortality rate of prostate cancer. In particular, unsupervised (automatic) prostate segmentation is an active and challenging research. Most conventional works usually utilize handcrafted (low-level) features for prostate segmentation; however they often fail to extract the intrinsic structure of the prostate, especially on images with blurred boundaries. In this paper, we propose a novel automated prostate segmentation model with learned features from deep network...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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