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https://www.readbyqxmd.com/read/29116303/non-invasive-brain-stimulation-and-computational-models-in-post-stroke-aphasic-patients-single-session-of-transcranial-magnetic-stimulation-and-transcranial-direct-current-stimulation-a-randomized-clinical-trial
#1
Michele Devido Dos Santos, Vitor Breseghello Cavenaghi, Ana Paula Machado Goyano Mac-Kay, Vitor Serafim, Alexandre Venturi, Dennis Quangvinh Truong, Yu Huang, Paulo Sérgio Boggio, Felipe Fregni, Marcel Simis, Marom Bikson, Rubens José Gagliardi
CONTEXT AND OBJECTIVE: Patients undergoing the same neuromodulation protocol may present different responses. Computational models may help in understanding such differences. The aims of this study were, firstly, to compare the performance of aphasic patients in naming tasks before and after one session of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and sham, and analyze the results between these neuromodulation techniques; and secondly, through computational model on the cortex and surrounding tissues, to assess current flow distribution and responses among patients who received tDCS and presented different levels of results from naming tasks...
November 6, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29018896/hypericum-perforatum-extract-modulates-cortical-plasticity-in-humans
#2
Carmen Concerto, Hyunji Boo, Charles Hu, Priam Sandilya, Anita Krish, Eileen Chusid, Diego Coira, Eugenio Aguglia, Fortunato Battaglia
BACKGROUND: Hypericum perforatum (HYP) extract is one of the most commonly used complementary alternative medicines (CAMs) for the treatment of mild-to-moderate depression. Non-invasive brain stimulation protocols can be used to investigate the effect of psychoactive substances on the human brain. In this study, we explored the effect of a single dose of HYP extract (WS 5570) intake on corticospinal excitability and plasticity in humans. METHODS: Twenty-eight healthy subjects were required to intake 900 mg of either HYP extract or placebo...
October 10, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28681660/strategies-for-replacing-non-invasive-brain-stimulation-sessions-recommendations-for-designing-neurostimulation-clinical-trials
#3
Aurore Thibaut, Anthony Terrence O'Brien, Felipe Fregni
Despite the potential impact of missed visits on the outcomes of neuromodulation treatments, it is not clear how this issue has been addressed in clinical trials. Given this gap in the literature, we reviewed articles on non-invasive brain stimulation in participants with depression or chronic pain, and investigated how missed visits were handled. Areas covered: We performed a search on PUBMED/MEDLINE using the keywords: 'tDCS', 'transcranial direct current stimulation', 'transcranial magnetic stimulation', 'depression', and 'pain'...
August 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28663570/brain-stimulation-in-obesity
#4
REVIEW
C H Göbel, V M Tronnier, T F Münte
Obesity is taking up epidemic proportions worldwide with significant impacts on the health of both the affected individual and on society as a whole. Treatment approaches consist of behavioural and pharmacological approaches, however, these are often found to be ineffective. In severe obesity, bariatric surgery is frequently performed. Unfortunately, 40% of patients show substantial weight gain over the long term or display the associated metabolic syndrome, making the development of novel therapies necessary...
June 30, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28610848/modulating-phonemic-fluency-performance-in-healthy-subjects-with-transcranial-magnetic-stimulation-over-the-left-or-right-lateral-frontal-cortex
#5
Daniela Smirni, Patrizia Turriziani, Giuseppa Renata Mangano, Martina Bracco, Massimiliano Oliveri, Lisa Cipolotti
A growing body of evidence have suggested that non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), can improve the performance of aphasic patients in language tasks. For example, application of inhibitory rTMS or tDCs over the right frontal lobe of dysphasic patients resulted in improved naming abilities. Several studies have also reported that in healthy controls (HC) tDCS application over the left prefrontal cortex (PFC) improve performance in naming and semantic fluency tasks...
June 10, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28516033/the-impact-of-large-structural-brain-changes-in-chronic-stroke-patients-on-the-electric-field-caused-by-transcranial-brain-stimulation
#6
Sena Minjoli, Guilherme B Saturnino, Jakob Udby Blicher, Charlotte J Stagg, Hartwig R Siebner, André Antunes, Axel Thielscher
Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (TDCS) are two types of non-invasive transcranial brain stimulation (TBS). They are useful tools for stroke research and may be potential adjunct therapies for functional recovery. However, stroke often causes large cerebral lesions, which are commonly accompanied by a secondary enlargement of the ventricles and atrophy. These structural alterations substantially change the conductivity distribution inside the head, which may have potentially important consequences for both brain stimulation methods...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28487249/combining-tdcs-with-prismatic-adaptation-for-non-invasive-neuromodulation-of-the-motor-cortex
#7
Martina Bracco, Giuseppa Renata Mangano, Patrizia Turriziani, Daniela Smirni, Massimiliano Oliveri
BACKGROUND: Prismatic adaptation (PA) shifts visual field laterally and induces lateralized deviations of spatial attention. Recently, it has been suggested that prismatic goggles are also able to modulate brain excitability, with cognitive after-effects documented even in tasks not necessarily spatial in nature. OBJECTIVE: The aim of the present study was to test whether neuromodulatory effects obtained from tDCS and prismatic goggles could interact and induce homeostatic changes in corticospinal excitability...
May 6, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28373927/non-invasive-brain-stimulation-for-essential-tremor
#8
REVIEW
Ludy C Shih, Alvaro Pascual-Leone
BACKGROUND: There is increasing interest in the use of non-invasive brain stimulation to characterize and potentially treat essential tremor (ET). Studies have used a variety of stimulation coils, paradigms, and target locations to make these observations. We reviewed the literature to compare prior studies and to evaluate the rationale and the methods used in these studies. METHODS: We performed a systematic literature search of the PubMed database using the terms "transcranial," "noninvasive," "brain stimulation," "transcranial magnetic stimulation (TMS)," "transcranial direct current stimulation (tDCS)," "transcranial alternating current stimulation (tACS)," and "essential tremor...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28353151/the-use-of-brain-stimulation-in-dysphagia-management
#9
REVIEW
Andre Simons, Shaheen Hamdy
Dysphagia is common sequela of brain injury with as many as 50% of patients suffering from dysphagia following stroke. Currently, the majority of guidelines for clinical practice in the management of dysphagia focus on the prevention of complications while any natural recovery takes place. Recently, however, non-invasive brain stimulation (NIBS) techniques like transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have started to attract attention and are applied to investigate both the physiology of swallowing and influences on dysphagia...
April 2017: Dysphagia
https://www.readbyqxmd.com/read/27881958/motor-cortex-neurostimulation-technologies-for-chronic-post-stroke-pain-implications-of-tissue-damage-on-stimulation-currents
#10
Anthony T O'Brien, Rivadavio Amorim, R Jarrett Rushmore, Uri Eden, Linda Afifi, Laura Dipietro, Timothy Wagner, Antoni Valero-Cabré
Background: Central post stroke pain (CPSP) is a highly refractory syndrome that can occur after stroke. Primary motor cortex (M1) brain stimulation using epidural brain stimulation (EBS), transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS) have been explored as potential therapies for CPSP. These techniques have demonstrated variable clinical efficacy. It is hypothesized that changes in the stimulating currents that are caused by stroke-induced changes in brain tissue conductivity limit the efficacy of these techniques...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27858095/-new-aspects-of-neurorehabilitation-motor-and-language
#11
REVIEW
J Liepert, C Breitenstein
Advancements in medical care over the last decades have contributed to a continuous decline in immediate post-stroke mortality. The flipside of this development is that patients surviving the initial stroke are forced to live with sometimes extreme functional motor and/or language limitations for the remaining life span. The following overview presents evidence-based neurorehabilitative interventions to promote motor and language recovery in the acute and chronic post-stroke stages. Therapeutic approaches comprise intensive training, neuropharmacological drugs and non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) or direct current stimulation (tDCS)...
December 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27804214/focus-of-attention-changes-intracortical-excitability-in-the-primary-motor-cortex
#12
EDITORIAL
W Marinovic
No abstract text is available yet for this article.
November 2, 2016: Acta Physiologica
https://www.readbyqxmd.com/read/27676869/pediatric-stroke-rehabilitation-a-review-of-techniques-facilitating-motor-recovery
#13
Eleni Papathanasiou, Mathilde Chevignard, Carole Vuillerot, Anne Tiberghien, Ingrid Godard
OBJECTIVE: Paediatric stroke is a relatively rare medical condition, but it often leads to long lasting motor and cognitive impairments. Rehabilitation of motor impairments has been widely studied, with most studies performed in children with cerebral palsy (CP). However, CP covers a variety of medical conditions, including brain lesions due to paediatric stroke occurring early in life, but not stroke occurring later on during childhood. The specificity of rehabilitation after paediatric stroke remains understudied...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27512367/non-invasive-brain-stimulation-to-enhance-post-stroke-recovery
#14
REVIEW
Nathalie Kubis
Brain plasticity after stroke remains poorly understood. Patients may improve spontaneously within the first 3 months and then more slowly in the coming year. The first day, decreased edema and reperfusion of the ischemic penumbra may possibly account for these phenomena, but the improvement during the next weeks suggests plasticity phenomena and cortical reorganization of the brain ischemic areas and of more remote areas. Indeed, the injured ischemic motor cortex has a reduced cortical excitability at the acute phase and a suspension of the topographic representation of affected muscles, whereas the contralateral motor cortex has an increased excitability and an enlarged somatomotor representation; furthermore, contralateral cortex exerts a transcallosal interhemispheric inhibition on the ischemic cortex...
2016: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/27387569/intra-subject-consistency-and-reliability-of-response-following-2%C3%A2-ma-transcranial-direct-current-stimulation
#15
Katherine Dyke, Soyoung Kim, Georgina M Jackson, Stephen R Jackson
BACKGROUND: Transcranial direct current stimulation (tDCS) is a popular non-invasive brain stimulation technique that has been shown to influence cortical excitability. While polarity specific effects have often been reported, this is not always the case, and variability in both the magnitude and direction of the effects have been observed. OBJECTIVE/HYPOTHESIS: We aimed to explore the consistency and reliability of the effects of tDCS by investigating changes in cortical excitability across multiple testing sessions in the same individuals...
November 2016: Brain Stimulation
https://www.readbyqxmd.com/read/27383993/optimizing-rehabilitation-for-phantom-limb-pain-using-mirror-therapy-and-transcranial-direct-current-stimulation-a-randomized-double-blind-clinical-trial-study-protocol
#16
Camila Bonin Pinto, Faddi Ghassan Saleh Velez, Nadia Bolognini, David Crandell, Lotfi B Merabet, Felipe Fregni
BACKGROUND: Despite the multiple available pharmacological and behavioral therapies for the management of chronic phantom limb pain (PLP) in lower limb amputees, treatment for this condition is still a major challenge and the results are mixed. Given that PLP is associated with maladaptive brain plasticity, interventions that promote cortical reorganization such as non-invasive brain stimulation and behavioral methods including transcranial direct current stimulation (tDCS) and mirror therapy (MT), respectively, may prove to be beneficial to control pain in PLP...
July 6, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27065796/non-invasive-brain-stimulation-in-conversion-functional-weakness-and-paralysis-a-systematic-review-and-future-perspectives
#17
REVIEW
Carlos Schönfeldt-Lecuona, Jean-Pascal Lefaucheur, Peter Lepping, Joachim Liepert, Bernhard J Connemann, Alexander Sartorius, Dennis A Nowak, Maximilian Gahr
Conversion (functional) limb weakness or paralysis (FW) can be a debilitating condition, and often causes significant distress or impairment in social, occupational, or other important areas of functioning. Most treatment concepts are multi-disciplinary, containing a behavioral approach combined with a motor learning program. Non-invasive brain stimulation (NIBS) methods, such as electroconvulsive therapy (ECT), and transcranial magnetic stimulation (TMS) have been used in the past few decades to treat FW. In order to identify all published studies that used NIBS methods such as ECT, TMS and transcranial direct current stimulation (tDCS) for treating FW patients a systematic review of the literature was conducted in PubMed and Web of Science...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/26903788/potential-mechanisms-supporting-the-value-of-motor-cortex-stimulation-to-treat-chronic-pain-syndromes
#18
REVIEW
Marcos F DosSantos, Natália Ferreira, Rebecca L Toback, Antônio C Carvalho, Alexandre F DaSilva
Throughout the first years of the twenty-first century, neurotechnologies such as motor cortex stimulation (MCS), transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS) have attracted scientific attention and been considered as potential tools to centrally modulate chronic pain, especially for those conditions more difficult to manage and refractory to all types of available pharmacological therapies. Interestingly, although the role of the motor cortex in pain has not been fully clarified, it is one of the cortical areas most commonly targeted by invasive and non-invasive neuromodulation technologies...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/26493498/efficacy-of-anodal-transcranial-direct-current-stimulation-is-related-to-sensitivity-to-transcranial-magnetic-stimulation
#19
Ludovica Labruna, Asif Jamil, Shane Fresnoza, Giorgi Batsikadze, Min-Fang Kuo, Benjamin Vanderschelden, Richard B Ivry, Michael A Nitsche
BACKGROUND: Transcranial direct current stimulation (tDCS) has become an important non-invasive brain stimulation tool for basic human brain physiology and cognitive neuroscience, with potential applications in cognitive and motor rehabilitation. To date, tDCS studies have employed a fixed stimulation level, without considering the impact of individual anatomy and physiology on the efficacy of the stimulation. This approach contrasts with the standard procedure for transcranial magnetic stimulation (TMS) where stimulation levels are usually tailored on an individual basis...
January 2016: Brain Stimulation
https://www.readbyqxmd.com/read/26409690/non-invasive-brain-stimulation-for-parkinson-s-disease-current-concepts-and-outlook-2015
#20
REVIEW
David H Benninger, Mark Hallett
BACKGROUND AND PURPOSE: In advanced Parkinson's disease (PD), the emergence of symptoms refractory to conventional therapy poses a therapeutic challenge. The success of deep brain stimulation (DBS) and advances in the understanding of the pathophysiology of PD have raised interest in non-invasive brain stimulation as an alternative therapeutic tool. The rationale for its use draws from the concept that reversing abnormalities in brain activity and physiology thought to cause the clinical deficits may restore normal functioning...
2015: NeuroRehabilitation
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