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https://www.readbyqxmd.com/read/27932432/fungal-mobile-mass-on-echocardiogram-native-mitral-valve-aspergillus-fumigatus-endocarditis
#1
Rymon Rofaiel, Yosra Turkistani, David McCarty, Seyed M Hosseini-Moghaddam
The most common type of infective endocarditis is bacterial endocarditis. However, fungal infections have been seen more frequently, mostly in the immunocompromised population. We report a case of invasive Aspergillus fumigatus native mitral valve endocarditis. The patient received appropriate empiric antifungal treatment with a combination of liposomal amphotericin B and flucytosine, associated with surgical debridement, valve replacement and chordae tendineae repair. Despite receiving the standard treatment of Aspergillus endocarditis, and susceptibility of the microorganism to the antifungal regimen, the patient, unexpectedly, developed early-onset septic emboli...
December 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27932362/predicting-functional-decline-in-older-emergency-patients-the-safe-elderly-emergency-discharge-seed-project
#2
Judy A Lowthian, Lahn D Straney, Caroline A Brand, Anna Barker, P de Villiers Smit, Harvey Newnham, Peter Hunter, Cathie Smith, Peter A Cameron
OBJECTIVE: to profile the trajectory of, and risk factors for, functional decline in older patients in the 30 days following Emergency Department (ED) discharge. METHODS: prospective cohort study of community-dwelling patients aged ≥65 years, discharged home from a metropolitan Melbourne ED, 31 July 2012 to 30 November 2013. The primary outcome was functional decline, comprising either increased dependency in personal activities of daily living (ADL) or in skills required for living independently instrumental ADL (IADL), deterioration in cognitive function, nursing home admission or death...
December 7, 2016: Age and Ageing
https://www.readbyqxmd.com/read/27932338/meaning-of-living-with-severe-chronic-obstructive-lung-disease-a-qualitative-study
#3
Gabriella Marx, Maximilian Nasse, Henrikje Stanze, Sonja Owusu Boakye, Friedemann Nauck, Nils Schneider
OBJECTIVES: To explore what it means for patients to live with chronic obstructive pulmonary disease (COPD) as an incurable and constantly progressing disease. DESIGN: Qualitative longitudinal study using narrative and semistructured interviews. This paper presents findings of the initial interviews. Analysis using grounded theory. SETTING: Lung care clinics and community care in Lower Saxony, Germany. PARTICIPANTS: 17 patients with advanced-stage COPD (Global Initiative for Chronic Obstructive Lung Disease (GOLD) III/IV)...
December 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27931580/changes-in-muscle-strength-and-six-minute-walk-distance-before-and-after-living-donor-liver-transplantation
#4
Y Mizuno, S Ito, K Hattori, M Nagaya, T Inoue, Y Nishida, Y Onishi, H Kamei, N Kurata, Y Hasegawa, Y Ogura
BACKGROUND: Impaired exercise capacity and muscle weakness are important characteristics of liver transplantation recipients. Perioperative rehabilitation has been introduced to promote early mobilization of patients and to prevent postoperative pulmonary complications. However, it is unknown how physical status recovers during the hospital stay after a liver transplant. The purpose of this study was to evaluate the changes in clinical indicators that represent the functional exercise capacity and muscle strength before and after living donor liver transplantation (LDLT)...
December 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27929335/intergenerational-transmission-of-socioeconomic-position-and-ideal-cardiovascular-health-32-year-follow-up-study
#5
Kateryna Savelieva, Laura Pulkki-Råback, Markus Jokela, Laura Diane Kubzansky, Marko Elovainio, Vera Mikkilä, Tuija Tammelin, Markus Juonala, Olli T Raitakari, Liisa Keltikangas-Järvinen
OBJECTIVES: Socioeconomic position (SEP) in childhood predicts cardiovascular health in adulthood but the underlying mechanisms remain unclear. Using a longitudinal study design, we examined the extent to which adult SEP acts as a pathway (mediator) connecting childhood SEP with adult cardiovascular health, and if upward social mobility mitigates the health-effects of early low SEP. METHOD: The sample comprised 697 participants from a prospective Finnish cohort followed during 32 years...
December 8, 2016: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/27928768/-reverse-torque-of-30%C3%A2-ncm-applied-to-dental-implants-as-test-for-osseointegration-a-human-observational-study
#6
Sabrina G Simeone, María Rios, Jeannette Simonpietri
BACKGROUND: On bone implantology, stability of a dental implant is an essential clinical tool during osseointegration evaluation, as it is a reflection of the structural and functional connection between the bone and the implant. METHODS: The sample was comprised by 17 patients with 40 NanoTec™ and Vellox® implants, placed on the lower jaw, under optimum conditions, after a minimum healing period of 3 months, during stage 2 surgery. RESULTS: All 40 implants showed ideal clinical stability after the 30 Ncm reverse torque...
December 2016: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/27928633/rna-processing-body-p-body-dynamics-in-mesophyll-protoplasts-re-initiating-cell-division
#7
Dilbag S Bhullar, Michael B Sheahan, Ray J Rose
The ability of plants to regenerate lies in the capacity of differentiated cells to reprogram and re-enter the cell cycle. Reprogramming of cells requires changes in chromatin organisation and gene expression. However, there has been less focus on changes at the post transcription level. We have investigated P-bodies, sites of post transcriptional gene regulation, in plant cell reprogramming in cultured mesophyll protoplasts; by using a YFP-VARICOSE (YFP-VCSc) translational fusion. We showed an early increase in P-body number and volume, followed by a decline, then a subsequent continued increase in P-body number and volume as cell division was initiated and cell proliferation continued...
December 7, 2016: Protoplasma
https://www.readbyqxmd.com/read/27928042/unexpected-high-vulnerability-of-functions-in-wilderness-areas-evidence-from-coral-reef-fishes
#8
Stéphanie D'agata, Laurent Vigliola, Nicholas A J Graham, Laurent Wantiez, Valeriano Parravicini, Sébastien Villéger, Gerard Mou-Tham, Philippe Frolla, Alan M Friedlander, Michel Kulbicki, David Mouillot
High species richness is thought to support the delivery of multiple ecosystem functions and services under changing environments. Yet, some species might perform unique functional roles while others are redundant. Thus, the benefits of high species richness in maintaining ecosystem functioning are uncertain if functions have little redundancy, potentially leading to high vulnerability of functions. We studied the natural propensity of assemblages to be functionally buffered against loss prior to fishing activities, using functional trait combinations, in coral reef fish assemblages across unfished wilderness areas of the Indo-Pacific: Chagos Archipelago, New Caledonia and French Polynesia...
December 14, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27927519/a-rapid-recovery-pathway-for-adolescent-idiopathic-scoliosis-that-improves-pain-control-and-reduces-time-to-inpatient-recovery-after-posterior-spinal-fusion
#9
Alex L Gornitzky, John M Flynn, Wallis T Muhly, Wudbhav N Sankar
STUDY DESIGN: Retrospective comparative cohort. OBJECTIVES: To determine if a standardized multimodal analgesic and rehabilitation protocol (rapid recovery pathway [RRP]) in adolescent idiopathic scoliosis (AIS) patients undergoing posterior spinal fusion (PSF) could improve pain control, reduce opioid-related complications, and expedite early mobilization. BACKGROUND: Several reports have described postoperative recovery pathways for AIS patients undergoing PSF that shorten length of stay (LOS) without reporting the impact such pathways might have on patients' pain or quality of recovery...
July 2016: Spine Deformity
https://www.readbyqxmd.com/read/27922766/diagnostic-value-of-high-mobility-group-box-1-hmgb1-protein-in-acute-and-perforated-appendicitis
#10
Shabanali Alizadeh, Ali Ghazavi, Ali Ganji, Ghasem Mosayebi
AIM: Acute appendicitis is the most common cause of abdominal surgical emergencies. Early diagnosis of appendicitis can reduce perforation and mortality rate. High-mobility group box 1 (HMGB1) protein has been identified as a pro-inflammatory factor and its elevated serum levels have been noted in different diseases. So, the aim of this study was to determine the serum levels of HMGB1 in patients with acute and perforated appendicitis in compare to normal appendix. MATERIAL AND METHODS: For this purpose, serum samples were obtained from 81 patients with primary criteria-based appendicitis 6 hr before and 72 hr after appendectomy, in which serum levels of HMGB1 were analyzed by enzyme-linked immunosorbent assay...
December 6, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27922064/ancient-tortoise-hunting-in-the-southwest-pacific
#11
Stuart Hawkins, Trevor H Worthy, Stuart Bedford, Matthew Spriggs, Geoffrey Clark, Geoff Irwin, Simon Best, Patrick Kirch
We report the unprecedented Lapita exploitation and subsequent extinction of large megafauna tortoises (?Meiolania damelipi) on tropical islands during the late Holocene over a 281,000 km(2) region of the southwest Pacific spanning from the Vanuatu archipelago to Viti Levu in Fiji. Zooarchaeological analyses have identified seven early archaeological sites with the remains of this distinctive hornless tortoise, unlike the Gondwanan horned meiolaniid radiation to the southwest. These large tortoise radiations in the Pacific may have contributed to the rapid dispersal of early mobile Neolithic hunters throughout southwest Melanesia and on to western Polynesia...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27919768/proximal-femoral-fractures-in-centenarians-a-retrospective-analysis-of-39-patients
#12
A Morice, N Reina, G Gracia, P Bonnevialle, J-M Laffosse, K Wytrykowski, E Cavaignac, N Bonnevialle
BACKGROUND: A corollary of the current population ageing in France is an increase in proximal femoral fractures (PFFs), particularly among centenarians. The outcomes of PFF in centenarians in France are unknown. We therefore conducted a retrospective study of centenarians with PFFs both to assess: 1) assess clinical outcomes according to geriatric and trauma scores, 2) and to determine whether routine surgery is warranted. HYPOTHESIS: Morbidity and mortality in a single-centre cohort of centenarians with surgically treated PFFs are consistent with previous reports...
December 2, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27919767/internal-fixation-of-intra-capsular-proximal-femoral-fractures-in-patients-older-than-80-years-still-relevant-multivariate-analysis-of-a-prospective-multicentre-cohort
#13
Nicolas Reina, Paul Bonnevialle, Brice Rubens Duval, Philippe Adam, François Loubignac, Thierry Favier, Philippe Massin
BACKGROUND: Arthroplasty is now widely used to treat intra-capsular proximal femoral fractures (PFFs) in older patients, even when there is little or no displacement. However, whether arthroplasty is associated with lower mortality and complication rates in non-displaced or mildly displaced PFFs is unknown. The objectives of this prospective study were: 1) to evaluate early mortality rates with the two treatment methods, 2) to identify risk factors for complications, 3) and to identify predictors of functional decline...
December 2, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27919706/extreme-lateral-lumbar-interbody-fusion-surgical-technique-outcomes-and-complications-after-a-minimum-of-one-year-follow-up
#14
I Domínguez, R Luque, M Noriega, J Rey, J Alia, F Marco-Martínez
«Minimally invasive» techniques have been recently been developed in order to achieve good clinical results with a low incidence of complications. The extralateral interbody fusion or direct transpsoas is a minimally invasive anterior arthrodesis. A total of 97 patients with 138 segments received surgery between May 2012 and May 2015. The follow-up was from 12-44 months. The mean age was 68 years (41-86). The most common cause of intervention was the adjacent segment (30%), deformity (22%), and lumbar disc disease (21%)...
December 2, 2016: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/27919275/rayyan-a-web-and-mobile-app-for-systematic-reviews
#15
Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz, Ahmed Elmagarmid
BACKGROUND: Synthesis of multiple randomized controlled trials (RCTs) in a systematic review can summarize the effects of individual outcomes and provide numerical answers about the effectiveness of interventions. Filtering of searches is time consuming, and no single method fulfills the principal requirements of speed with accuracy. Automation of systematic reviews is driven by a necessity to expedite the availability of current best evidence for policy and clinical decision-making. We developed Rayyan ( http://rayyan...
December 5, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27918395/early-mobilization-in-critically-ill-children-ready-for-implementation
#16
Karen Choong
No abstract text is available yet for this article.
December 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27917961/trends-in-health-surveillance-and-joint-service-delivery-for-pastoralists-in-west-and-central-africa
#17
M F Abakar, E Schelling, M Béchir, B N Ngandolo, K Pfister, I O Alfaroukh, H M Hassane, J Zinsstag
In most sub-Saharan African countries, pastoralism represents an important economic resource and contributes significantly to national growth; however, challenges remain, particularly in providing social services to pastoralists (especially health and education) and in avoiding conflict with local sedentary communities and local authorities. All of this takes place while pastoralists try to maintain their mobile lifestyle within a rapidly changing ecosystem. Transdisciplinary approaches, such as 'One Health', which covers both human and animal health, have proven effective in delivering services and reaching mobile pastoralists in remote areas...
November 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/27917688/congenital-thumb-anomalies-and-the-consequences-for-daily-life-patients-long-term-experience-after-corrective-surgery-a-qualitative-study
#18
I K Carlsson, L B Dahlin, H-E Rosberg
PURPOSE: The aim of the study was to explore patients' long-term experience of a congenital hand problem, and the consequences for daily life. METHOD: Fifteen participants with a median age 24 years (17-55 years), born with thumb hypoplasia/aplasia or thumb duplication were interviewed using a semi-structured interview guide. The interviews were subjected to qualitative content analysis. RESULTS: Although the mobility and strength in the thumb/hand(s) varied within the group, hand function was generally described as good...
December 5, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27916598/pic-activation-through-functional-interplay-between-mediator-and-tfiih
#19
Sohail Malik, Henrik Molina, Zhu Xue
The multiprotein Mediator coactivator complex functions in large part by controlling formation and function of the promoter-bound preinitiation complex (PIC), which consists of RNA polymerase II (Pol II) and general transcription factors. However, precisely how Mediator impacts the PIC, especially post-recruitment, has remained unclear. Here, we have studied Mediator effects on basal transcription in an in vitro transcription system reconstituted from purified components. Our results reveal a close functional interplay between Mediator and TFIIH in the early stages of PIC development...
December 1, 2016: Journal of Molecular Biology
https://www.readbyqxmd.com/read/27913814/life-course-socioeconomic-adversities-and-10-year-risk-of-cardiovascular-disease-cross-sectional-analysis-of-the-brazilian-longitudinal-study-of-adult-health
#20
Dayse Rodrigues de Sousa Andrade, Lidyane V Camelo, Rodrigo Citton P Dos Reis, Itamar S Santos, Antonio Luiz Ribeiro, Luana Giatti, Sandhi Maria Barreto
OBJECTIVES: To investigate whether life course exposure to adverse socioeconomic positions (SEP) as well as maintaining a low SEP or decreasing the SEP intra- and intergeneration was associated with an increased 10-year cardiovascular disease (CVD) risk predicted by the Framingham Risk Score. METHODS: This is a cross-sectional analysis of baseline data (2008-2010) of 13,544 active workers from ELSA-Brasil cohort. Maternal education, leg length, social class of first occupation and education were used to evaluate childhood, youth and adulthood SEP...
December 2, 2016: International Journal of Public Health
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