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https://www.readbyqxmd.com/read/28820985/human-bone-marrow-as-a-tissue-in-post-mortem-identification-and-determination-of-psychoactive-substances-screening-methodology
#1
Renata Wietecha-Posłuszny, Sofia Lendor, Magdalena Garnysz, Marcin Zawadzki, Paweł Kościelniak
The aim of this study was to apply a new instrumental approach to the analysis of human bone marrow for forensic purposes. A new screening method for the detection of more than 30 psychoactive drugs in bone marrow was developed and applied to case samples. The drugs used in this study belonged to the following groups: benzodiazepines (BZDs, n=16), tricyclic antidepressants (TCAs, n=5), selective serotonin reuptake inhibitors (SSRI, n=4), serotonin-norepinephrine reuptake inhibitors (n=1), anticonvulsants (n=1), imidazopyridines (n=1) and piperazines (n=3)...
August 7, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28820153/learning-curve-of-femtosecond-laser-assisted-cataract-surgery-experience-of-surgeons-new-to-femtosecond-laser-platform
#2
Josephine Susai Christy, Manas Nath, Fredrick Mouttapa, Rengaraj Venkatesh
PURPOSE: The purpose of this study is to assess the learning curve in the initial 100 cases of cataract surgery performed using femtosecond laser-assisted cataract surgery (FLACS) by experienced cataract surgeons without prior experience in femtosecond laser platform. METHODS: This study was conducted at tertiary care eye hospital, South India. This was a prospective interventional study. The first 100 consecutive eyes undergoing FLACS were studied to understand docking time, number of docking attempts, problems encountered during docking, and complications attributable to docking...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28817452/cms-mds-3-0-section-m-skin-conditions-in-long-term-care-pressure-ulcers-skin-tears-and-moisture-associated-skin-damage-data-update
#3
Elizabeth A Ayello
GENERAL PURPOSE: The purpose of this learning activity is to provide information about the updates to the Centers for Medicare & Medicaid Services (CMS) MDS 3.0 Section M, Skin Conditions documentation in long-term care. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant should be better able to:1...
September 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28814056/design-of-a-lightweight-tethered-torque-controlled-knee-exoskeleton
#4
Kirby Ann Witte, Andreas M Fatschel, Steven H Collins
Lower-limb exoskeletons show promise for improving gait rehabilitation for those with chronic gait abnormalities due to injury, stroke or other illness. We designed and built a tethered knee exoskeleton with a strong lightweight frame and comfortable, four-point contact with the leg. The device is structurally compliant in select directions, instrumented to measure joint angle and applied torque, and is lightweight (0.76 kg). The exoskeleton is actuated by two off-board motors. Closed loop torque control is achieved using classical proportional feedback control with damping injection in conjunction with iterative learning...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813995/a-novel-human-effort-estimation-method-for-knee-assistive-exoskeletons
#5
Lorenzo Saccares, Anais Brygo, Ioannis Sarakoglou, Nikos G Tsagarakis
In this work we present a novel method to estimate online the torques at the knee joints with the goal to generate reference signals for knee assistive devices. One of the main advantages of the proposed approach is its reduced sensing requirements, which leads to an ergonomic setup with minimal instrumentation, especially above the knee and of the upper body. Indeed, only the measurement of the forces and torques exchanged between the ground and the user's feet, the posture of the shanks, and the model of the user's shank itself are needed for the estimation of the knee torque...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813868/relationship-between-assistive-torque-and-knee-biomechanics-during-exoskeleton-walking-in-individuals-with-crouch-gait
#6
Zachary F Lerner, Diane L Damiano, Thomas C Bulea
Crouch or "flexed knee" gait is a pathological gait pattern affecting many individuals with cerebral palsy. One proposed method to alleviate crouch is to provide robotic assistance to knee extension during walking. The purpose of this study was to evaluate how the magnitude of knee extensor torque affects knee kinematics, kinetics, and muscle activity. Motion capture, ground reaction force and electromyography data were collected while four participants with crouch gait from cerebral palsy walked with assistance from a novel robotic exoskeleton on an instrumented treadmill...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813841/design-and-preliminary-evaluation-of-a-multi-robotic-system-with-pelvic-and-hip-assistance-for-pediatric-gait-rehabilitation
#7
Evelyn J Park, Jiyeon Kang, Hao Su, Paul Stegall, Daniel L Miranda, Wen-Hao Hsu, Mustafa Karabas, Nathan Phipps, Sunil K Agrawal, Eugene C Goldfield, Conor J Walsh
This paper presents a modular, computationally-distributed "multi-robot" cyberphysical system designed to assist children with developmental delays in learning to walk. The system consists of two modules, each assisting a different aspect of gait: a tethered cable pelvic module with up to 6 degrees of freedom (DOF), which can modulate the motion of the pelvis in three dimensions, and a two DOF wearable hip module assisting lower limb motion, specifically hip flexion. Both modules are designed to be lightweight and minimally restrictive to the user, and the modules can operate independently or in cooperation with each other, allowing flexible system configuration to provide highly customized and adaptable assistance...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28803806/the-use-of-computer-assisted-corticotomy-to-enhance-surgical-procedures
#8
Marco Finotti, Antonio Gracco, Mariarosa Del Torre, Laura Siviero, Alberto de Stefani, Giovanni Bruno
In recent years, several surgical techniques have been proposed with the main goal of reducing the length of orthodontic treatment. Some of these techniques use a piezoelectric surgical instrument to perform alveolar bone cuts and promote localized bone turnover. One of the main limitations of these surgical techniques is that corticotomies may damage dental roots since traditional radiographic examinations do not allow the surgeon to precisely determine the length and three-dimensional position of the roots...
August 10, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28802703/identification-and-characterization-of-clostridium-botulinum-group-iii-field-strains-by-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry-maldi-tof-ms
#9
Luca Bano, Ilenia Drigo, Elena Tonon, Simone Pascoletti, Cinzia Puiatti, Fabrizio Anniballi, Bruna Auricchio, Florigio Lista, Cesare Montecucco, Fabrizio Agnoletti
Animal botulism is primarily due to botulinum neurotoxin (BoNT) types C, D or their chimeric variants C/D or D/C, produced by Clostridium botulinum group III, which appears to include the genetically indistinguishable Clostridium haemolyticum and Clostridium novyi. In the present study, we used matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI TOF MS) to identify and characterize 81 BoNT-producing Clostridia isolated in 47 episodes of animal botulism. The instrument's default database, containing no entries for Clostridium botulinum, permitted reliable identification of 26 strains at the genus level...
August 10, 2017: Anaerobe
https://www.readbyqxmd.com/read/28802025/simple-and-rapid-determination-of-zaltoprofen-in-human-plasma-by-manual-shaking-assisted-dispersive-liquid-liquid-microextraction-followed-by-liquid-chromatography-with-ultraviolet-detection
#10
Se Young Han, Kyung Min Jeong, Da Eun Yoo, Yan Jin, Eun Mi Kim, Su Hyun Kim, Seok-Yong Lee, Se-Hyung Kim, Jing Zhao, Jeongmi Lee
A readily applicable method was developed to determine the concentration level of zaltoprofen, a non-steroidal anti-inflammatory drug from the propionic acid family, in human plasma. This method is based on manual shaking-assisted dispersive liquid-liquid microextraction coupled with liquid chromatography with UV detection. Factors affecting the extraction efficiency were screened and optimized by experimental design using fractional factorial and central composite designs, respectively. Optimal conditions were: 220 μL of C2 H4 Cl2 (extraction solvent), 5 mL of 3...
August 12, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28801863/pedicle-screw-fixation-in-thoracolumbar-and-lumbar-spine-assisted-by-lateral-fluoroscopic-imaging-a-study-to-evaluate-the-accuracy-of-screw-placement
#11
S P Mohanty, S N Bhat, M Pai Kanhangad, G S Gosal
BACKGROUND: The purpose of this study was to evaluate the accuracy of pedicle screw placement, its advantages, and limitations in posterior instrumentation of thoracolumbar and lumbar burst fractures assisted only by lateral fluoroscopic imaging. MATERIALS AND METHODS: Pre- and postoperative computerized tomographic (CT) scans of 117 patients with thoracolumbar and lumbar burst fractures, who underwent posterior instrumentation with pedicle screw fixation, were prospectively analyzed...
August 11, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28801836/optimization-of-sample-preparation-and-instrumental-parameters-for-the-rapid-analysis-of-drugs-of-abuse-in-hair-samples-by-maldi-ms-ms-imaging
#12
Bryn Flinders, Emma Beasley, Ricky M Verlaan, Eva Cuypers, Simona Francese, Tom Bassindale, Malcolm R Clench, Ron M A Heeren
Matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) has been employed to rapidly screen longitudinally sectioned drug user hair samples for cocaine and its metabolites using continuous raster imaging. Optimization of the spatial resolution and raster speed were performed on intact cocaine contaminated hair samples. The optimized settings (100 × 150 μm at 0.24 mm/s) were subsequently used to examine longitudinally sectioned drug user hair samples. The MALDI-MS/MS images showed the distribution of the most abundant cocaine product ion at m/z 182...
August 11, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28800437/beyond-the-latch-a-new-approach-to-breastfeeding
#13
Betty Ann Robinson, Gweneth Hartrick Doane
Health professionals supporting breastfeeding play an important role in women successfully achieving their breastfeeding goals. Instrumental knowledge has dominated health professionals' breastfeeding education and practice. Because breastfeeding is a contextual and embodied experience, a relational orientation is required to identify effective strategies to support women. A relational inquiry approach to breastfeeding practice offers a practical way to support women to better achieve their breastfeeding goals within the complexities of their own lives...
August 1, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28797939/informal-assistance-to-urban-families-and-the-risk-of-household-food-insecurity
#14
Christian King
RATIONALE: Food insecurity is a persistent social problem affecting one out of eight households in the United States. While evidence shows that public assistance programs (formal assistance) are effective in reducing food insecurity, there is more limited evidence documenting how informal support, through social capital, affects food insecurity. OBJECTIVE: To examine the role of informal support (through instrumental social support, social cohesion, social control, and social participation) on food insecurity transitions using longitudinal data of a sample of disadvantaged urban mothers from the Fragile Families and Child Wellbeing Study...
August 2, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28796072/one-visualization-simulation-operation-system-for-distal-femoral-fracture
#15
Dan Wang, Ning Li, Ming Luo, Yao-Kun Chen
A computer-aided 3-dimensional (3D) visualization operation simulation system based on computer-aided design (CAD) Unigraphics NX and Mimics software was established to provide orthopedic surgeons with an actual and reliable system in treating of distal femoral fracture.According to the preoperative CT data, 3D reconstruction of the distal femoral fracture could be achieved by the Mimics software. Then, the CAD Unigraphics NX software was used to measure the model function of all the related surgical instruments, including less invasive stabilization system (LISS) and retrograde intramedullary nail fixation...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28795900/translation-and-testing-of-the-italian-version-of-famcare-2-measuring-family-caregivers-satisfaction-with-palliative-care
#16
Daniela D'Angelo, Antonella Cinzia Punziano, Chiara Mastroianni, Annamaria Marzi, Roberto Latina, Valerio Ghezzi, Michela Piredda, Maria Grazia De Marinis
Family satisfaction is an important outcome of palliative care and is a critical measure for health care professionals to address when assessing quality of care. The FAMCARE-2 is a widely used measure of family satisfaction with the health care received by both patient and family in palliative care. In this study, a team of Italian researchers culturally adapted the FAMCARE-2 to the Italian language and psychometrically tested the instrument by measuring satisfaction of 185 family caregivers of patients admitted into two palliative care services...
May 2017: Journal of Family Nursing
https://www.readbyqxmd.com/read/28794585/current-status-of-robotic-single-port-surgery
#17
REVIEW
Ryan J Nelson, Jaya Sai S Chavali, Nitin Yerram, Paurush Babbar, Jihad H Kaouk
Robotic-assisted laparoscopic surgery in urology is an ever progressing field, and boundaries are constantly broken with the aid of new technology. Advancements in instrumentation have given birth to the era of robotic laparoendoscopic single-site technique (R-LESS). R-LESS however, has not gained widespread acceptance due to technical hurdles such as adequate triangulation, robotic arm clashing, decreased access for the bedside assistant, lack of wrist articulation, continued need for an axillary/accessory port, lack of robust retraction, and ergonomic discomfort...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28793761/miniaturized-thermal-assisted-purge-and-trap-technique-coupling-with-surface-enhanced-raman-scattering-for-trace-analysis-of-complex-samples
#18
Zhengyi Chen, Gongke Li, Zhuomin Zhang
It still remains a great challenge for quantification of trace analytes in complex samples by surface-enhanced Raman scattering (SERS) technique due to potential matrix influence or weak SERS responses of analytes. In this work, a miniaturized thermal-assisted purge-and-trap (MTAPT) device was designed and developed to eliminate matrix influence coupled with derivatization method before SERS analysis. The design of MTAPT chamber was optimized based on quantitative calculation of its dead volume by computational fluid dynamics simulation...
August 10, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28793075/-coordination-between-pharmaceutical-services-for-integrated-pharmacotherapy-the-case-of-catalonia
#19
Karen Sarmento Costa, Moisés Goldbaum, Rafel Guayta-Escolies, Pilar Modamio, Eduardo Luis Mariño, José Luis Segú Tolsá
Pharmaceutical policies have been considered strategies to contribute to the guarantee of care coordination and clinical integration. This study sought to describe the pharmaceutical services developed at different levels of care in the health network in Catalonia, as well as to identify and analyze the mechanisms and instruments that act as facilitators and/or barriers to the coordination of pharmacotherapy. This is a descriptive study of 12 cases of hospital pharmacy services, primary care and community pharmacies...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28792829/mental-health-problems-among-nurses-in-paediatric-cardiac-intensive-care
#20
Renata Santos Tito, Patrícia Campos Pavan Baptista, Fabio José da Silva, Vanda Elisa Andres Felli
At present, there are growing rates of psychiatric symptoms among some occupational categories, with emphasis on health professionals who work in hospitals. This study aimed to identify the occurrence of mental health problems (anxiety and depression) among 92 nursing workers in a paediatric cardiac intensive care unit. This is an exploratory, cross-sectional study, with a quantitative approach. The research was conducted in a public university hospital specialising in cardiology, pneumology, and thoracic and cardiac surgery...
August 10, 2017: British Journal of Nursing: BJN
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