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https://www.readbyqxmd.com/read/29210713/intradermal-proliferative-fasciitis-occurring-with-chondrodermatitis-nodularis-helicis
#1
Ashley Elsensohn, Sasha Getty, Jessica Shiu, Sébastien de Feraudy
Nodular fasciitis is a benign myofibroblastic tumor. Its uncommon variant, proliferative fasciitis (PF), can present in an even less common intradermal form. We report a case of intradermal PF of the ear in a 45-year-old man who presented with recurrent episodes of pain and swelling of the lesion. Histologic examination showed a dermal, nodular proliferation of ganglion-like basophilic fibroblasts with prominent nuclei and nucleoli, admixed with foamy histiocytes and areas of spindle cells arranged in intersecting fascicles in a fibromyxoid background...
November 21, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29196220/new-chalcone-compound-as-a-promising-antileishmanial-drug-for-an-old-neglected-disease-biological-evaluation-using-radiolabeled-biodistribution
#2
Ariane de J Sousa-Batista, Cíntia I M Silva Philipon, Marta de Souza Albernaz, Suyene Rocha Pinto, Bartira Rossi-Bergmann, Ralph Santos-Oliveira
INTRODUCTION: The current treatment of leishmaniasis remains a challenge, especially due to the need for multiple painful injections, the toxicity of the current drugs against the disease, the lack of efficacy and, lately the drug-resistant. OBJECTIVES: To demonstrate the biological behavior of 3-nitro-2-hydroxi-4,6-dimetoxychalcone (CH8) in animal model of cutaneous (CL) and visceral (VL) leishmaniasis Methodology: In order to evaluate itsbiological behavior the CH8 compound has been radiolabeled with 99mTc using the direct reaction...
November 28, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29192304/association-of-hearing-loss-and-otologic-outcomes-with-fibrous-dysplasia
#3
Alison M Boyce, Carmen Brewer, Timothy R DeKlotz, Christopher K Zalewski, Kelly A King, Michael T Collins, H Jeffrey Kim
Importance: Fibrous dysplasia (FD) and McCune-Albright syndrome (MAS) are rare bone and endocrine disorders in which expansile fibro-osseous lesions result in deformity, pain, and functional impairment. The effect of FD on hearing and otologic function has not been established. Objectives: To characterize audiologic and otologic manifestations in a large cohort of individuals with FD/MAS and to investigate potential mechanisms of hearing loss. Design, Setting, and Participants: In this natural history study, individuals with craniofacial FD seen at a clinical research center underwent clinical, biochemical, computed tomographic, audiologic, and otolaryngologic evaluations...
November 30, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29189591/luc-s-abscess-and-temporomandibular-joint-septic-arthritis-two-rare-sequelae-of-acute-otitis-media
#4
Carmelle Tsai, Jennifer Deramo, Xiaofan Shen, Kathleen Vandiver, Vineeta Mittal
A 5-year-old previously healthy child presented with right-sided otalgia, right facial and temporal swelling, and right jaw pain in the setting of 6 days of low-grade fever. The child had no trauma, vomiting, or prior dental treatments. On physical examination, the patient had facial swelling, erythema, and tenderness over the right temporal region along with trismus, as well as pain on palpation of the right temporomandibular joint (TMJ). A computed tomography scan revealed otitis media, Luc's abscess, and TMJ septic arthritis requiring surgical drainage and intravenous antibiotics...
November 20, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29181524/challenging-case-of-parotitis-a-comprehensive-approach
#5
Puja Patel, Shannon Scott, Sean Cunningham
The diagnosis and management of parotitis can be challenging. Patients often present with pain and edema in the neck, jaw, head, and ear due to congestion of the gland. Parotitis is typically caused by an infection within the parotid gland and surrounding lymph nodes, and the infection can spread to nearby cervical fascial planes and cause major complications if not managed successfully. Specific guidelines for the outpatient management of parotitis are limited, and outpatient treatment failures are common, requiring inpatient therapy with multiple broad-spectrum antibiotics...
December 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29181262/exercise-manual-therapy-and-postural-re-education-for-uncontrolled-ear-twitching-and-related-impairments-after-whiplash-injury-a-case-report
#6
Kelsey Flanders, Heather Feldner
Background and Purpose: Whiplash Associated Disorders and the interventions used to remediate them are well documented in physical therapy literature. However, specific interventions for spasms of the neck musculature that also involve constant ear twitching have yet to be addressed. The purpose of this case report is twofold. First, to describe comprehensive physical therapy management and outcomes for a subject with uncontrolled ear twitching and related musculoskeletal impairments, and second, to discuss the physical therapist's approach to evidence-based care when faced with a paucity of literature addressing physical therapy interventions for subjects with uncontrolled ear twitching...
October 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29180123/childhood-versus-adult-onset-anca-associated-vasculitides-a-nested-matched-case-control-study-from-the-french-vasculitis-study-group-registry
#7
REVIEW
Michele Iudici, Christian Pagnoux, Pierre Quartier, Matthias Büchler, Ramiro Cevallos, Pascal Cohen, Claire de Moreuil, Philippe Guilpain, Alain Le Quellec, Jacques Serratrice, Benjamin Terrier, Loïc Guillevin, Luc Mouthon, Xavier Puéchal
OBJECTIVE: To investigate differences between childhood-onset ANCA-associated vasculitides (cAAVs) and matched adult-onset controls (aAAVs). METHODS: cAAV clinical pictures at onset and outcomes were compared to a randomly selected sample of aAAV patients from the French Vasculitis Study Group Registry. Cases and controls were matched for AAV (granulomatosis with polyangiitis [GPA], microscopic polyangiitis [MPA] or eosinophilic granulomatosis with polyangiitis [EGPA]), sex and year of enrollment...
November 24, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29167728/predicting-the-risk-of-hearing-impairment-following-the-cervical-spine-diseases-by-measuring-the-cervical-range-of-movements-a-pilot-study
#8
Behnoosh Vasaghi-Gharamaleki, Zahra Naser
Introduction: Cervical spine abnormalities can affect the ear vessels and or nerves with different mechanisms. Ear dysfunctions following cervical spine injuries can be manifested as hearing loss, vertigo, or tinnitus. Usually, cervical spine injuries can cause pain and Range of Motion (ROM) limitation. The major objective of this study was to determine which cervical ROM limitation was accompanied with higher level of hearing loss. Methods: In this cross-sectional study, 42 volunteers (20 women and 22 men) with cervical spine injury and pain participated after giving their informed consent...
September 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/29152430/a-dosimetric-comparison-of-intensity-modulated-proton-therapy-volumetric-modulated-arc-therapy-and-4%C3%AF-non-coplanar-intensity-modulated-radiation-therapy-for-a-patient-with-parameningeal-rhabdomyosarcoma
#9
Tiffany W Chen, Julian Sison, Becky Lee, Arthur J Olch, Andrew Chang, Annelise Giebeler, Kenneth Wong
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and manifests as two major histological subtypes: embryonal and alveolar. The five-year local failure rate for RMS at parameningeal sites (middle ear, mastoid region, nasal cavity, etc.) is around 17% despite multiple Intergroup Rhabdomyosarcoma Study Group (IRS) trials conducted to determine the optimal radiation treatment regimen. This case report explores the use of intensity-modulated proton therapy (IMPT) for a 10-year-old child who presented with left eye irritation, facial pain, and headaches and was found to have an alveolar parameningeal rhabdomyosarcoma...
September 10, 2017: Curēus
https://www.readbyqxmd.com/read/29152209/case-control-study-hyperbaric-oxygen-treatment-of-mild-traumatic-brain-injury-persistent-post-concussion-syndrome-and-post-traumatic-stress-disorder
#10
Paul G Harch, Susan R Andrews, Edward F Fogarty, Juliette Lucarini, Keith W Van Meter
Mild traumatic brain injury (TBI) persistent post-concussion syndrome (PPCS) and post-traumatic stress disorder (PTSD) are epidemic in United States Iraq and Afghanistan War veterans. Treatment of the combined diagnoses is limited. The aim of this study is to assess safety, feasibility, and effectiveness of hyperbaric oxygen treatments (HBOT) for mild TBI PPCS and PTSD. Thirty military subjects aged 18-65 with PPCS with or without PTSD and from one or more blast-induced mild-moderate traumatic brain injuries that were a minimum of 1 year old and occurred after 9/11/2001 were studied...
July 2017: Medical Gas Research
https://www.readbyqxmd.com/read/29147477/vanishing-vasculitis-a-case-of-acute-necrotic-skin-findings-without-pathologic-features-of-vasculitis-from-adulterated-cocaine
#11
Adnan Asif Parvez Ghias, Patrick Brine
While the usage of illicit drugs in itself carries significant health risks and associated toxicities, drugs that are adulterated to give them volume, alter their psychogenic properties, and make them cheaper to produce are to be considered even more dangerous. Cocaine is one of them, and it is now most commonly being adulterated with levamisole. We report a case of a 37-year-old female with the chief complaint of painful skin lesions and wounds on both of her upper and lower extremities for three weeks duration...
2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29138954/identification-of-compounds-from-palicourea-rigida-leaves-with-topical-anti-inflammatory-potential-using-experimental-models
#12
Rafael P Pinheiro, Muiara A Moraes, Bruna C S Santos, Rodrigo L Fabri, Glauciemar Del-Vechio-Vieira, Célia H Yamamoto, Ana Lúcia S M Araújo, Aílson L A Araújo, Orlando V Sousa
Palicourea rigida Kunth is traditionally used for the treatment of skin diseases, kidney pains and ovarian inflammation. Based on these traditional uses, this study evaluated the topical anti-inflammatory activity of the ethanol extract from P. rigida leaves (EEPR) and identified bioactive compounds. Ear edema was induced in Swiss mice by the topical application of Croton oil, arachidonic acid, phenol and capsaicin. Histopathological analysis and myeloperoxidase and N-acetyl-β-D-glucosaminidase activities were determined...
November 14, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/29131858/the-composition-and-initial-evaluation-of-a-grimace-scale-in-ferrets-after-surgical-implantation-of-a-telemetry-probe
#13
Marsinah L Reijgwart, Nico J Schoemaker, Riccardo Pascuzzo, Matthew C Leach, Melanie Stodel, Loes de Nies, Coenraad F M Hendriksen, Miriam van der Meer, Claudia M Vinke, Yvonne R A van Zeeland
Reliable recognition of pain is difficult in ferrets as many currently available parameters are non-specific, inconsistent and/or impractical. Grimace scales have successfully been applied to assess pain in different animal species and might also be applicable to ferrets. To compose a Ferret Grimace Scale (FGS), we studied the facial musculature of ferrets and compared lateral photographs of 19 ferret faces at six time points before and after intraperitoneal telemetry probe implantation. We identified the Action Units (AUs) orbital tightening, nose bulging, cheek bulging, ear changes and whisker retraction as potential indicators of pain in ferrets...
2017: PloS One
https://www.readbyqxmd.com/read/29112942/acupuncture-for-primary-dysmenorrhea-a-meta-analysis-of-randomized-controlled-trials
#14
Tong Liu, Jia-Ni Yu, Bing-Yan Cao, Yuan-Yuan Peng, Yu-Pei Chen, Li Zhang
Context • Primary dysmenorrhea (PD) is one of the most common complaints among young women. Acupuncture has been widely applied as a therapeutic modality in China and abroad for PD; however, the evidence for its benefits is still not convincing. Objective • The study intended to conduct a systematic review of randomized, controlled trials (RCTs) to evaluate the evidence regarding the use of acupuncture in treating PD. Design • The research team retrieved reports for RCTs published in 7 databases from their inception to March 2016, with no language restrictions: PubMed, Medline, Embase, the Cochrane Central Register of Controlled Trials, the Chinese National Knowledge Infrastructure database, the Chinese Biomedical database, and the Wanfang database...
November 7, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29103774/a-single-arm-open-label-clinical-trial-of-autologous-epidermal-cell-transplantation-for-stable-vitiligo-a-30-month-follow-up
#15
Zahra Orouji, Amir Bajouri, Mahshid Ghasemi, Parvaneh Mohammadi, Nasrin Fallah, Atefeh Shahbazi, Mohammad Rezvani, Fatemeh Vaezirad, Zahra Khalajasadi, Ahad Alizadeh, Ehsan Taghiabadi, Sara Dashtbozorgi, Raheleh Aghdami, Seyedeh Esmat Hosseini, Hossein Bahahrvand, Saeed Shafieyan, Nasser Aghdami
BACKGROUND: Recently, we introduced intralesional injection of autologous epidermal cells as a safe and feasible approach for transplantation in patients with stable vitiligo. This approach resulted in less pain during and after the procedure, no scarring or cobblestone formation at the recipient site, and was more feasible to perform on curved surfaces such as joints, lips, eyelids, ears, and face. OBJECTIVE: In this study, we aimed to investigate the long-term efficacy and safety of this transplantation technique...
October 18, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29098132/mycotic-pseudoaneurysm-associated-with-skull-base-osteomyelitis-treated-with-endovascular-embolization
#16
Ali S Haider, Brandon I Esianor, Mrigank S Shail, Margaret I Engelhardt, Aida Kafai Golahmadi, Ramiz Khan, Umair Khan, Steven Vayalumkal, Richa Thakur, Kennith F Layton
Pseudoaneurysms occur due to malformations in arterial wall uniformity, leading to blood collection between the outer arterial layers and resultant outpouching of the vessel. Unlike true aneurysms, pseudoaneurysms do not involve all layers of the blood vessel. Mycotic pseudoaneurysms can occur after associated vessel adventitia infection, leading to transmural dissection. Here we present a case of a 78-year-old man with a history of chronic otitis externa and osteomyelitis who presented with increasing right ear pain with bloody discharge and associated headache...
August 28, 2017: Curēus
https://www.readbyqxmd.com/read/29077540/toward-reduction-in-antibiotic-use-for-pediatric-otitis-media-predicting-parental-compliance-with-watchful-waiting-advice
#17
Erina L MacGeorge, Rachel A Smith, Emily P Caldes, Nicole M Hackman
"Watchful waiting" (WW) can reduce unnecessary antibiotic use in the treatment of pediatric otitis media (ear infection), but the utility of the strategy is impaired by underutilization and noncompliance. Guided by advice response theory (ART), the current study examines how parental compliance with WW and trust in the prescribing physician is predicted by evaluative and affective responses to the advice. Parents (N = 134) of at least one child aged 5 years or younger completed questionnaires that assessed responses to WW advice they received for their youngest child...
November 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/29071898/-distribution-of-press-sensitive-acupoints-in-patients-with-tinnitus
#18
Mei-Qi Ji, Shan-Shan Tian, Dai Liu, Wei Zhang, Jie-Ping Xie, Ya-Li Zhang, Chun-Hua Li, Yan Gao
OBJECTIVE: To explore the regularity of distribution of press-sensitive acupoints on the body surface in tinnitus patients, so as to provide evidence for selecting suitable acupuncture points in the treatment of tinnitus. METHODS: Sixty-three cases of tinnitus patients (from 25 to 75 years in age) were recruited in the present study. The patient was asked to take a sitting, supine and prone position, successively, and the operator used the thumb to moderately press the subject's head, neck, back, four limbs below the knee- and elbow joints along the three Hand- and three Foot-yang and yin meridians...
December 25, 2016: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29067138/does-ear-acupuncture-have-a-role-for-pain-relief-in-the-emergency-setting-a-systematic-review-and-meta-analysis
#19
REVIEW
Andrew L Jan, Emogene S Aldridge, Ian R Rogers, Eric J Visser, Max K Bulsara, Richard C Niemtzow
Objective: Ear acupuncture might be the form of acupuncture best suited to improving acute pain management in the emergency department (ED). The primary aim of this review was to assess the analgesic efficacy of ear acupuncture in the ED. Secondary outcomes included measures of patient satisfaction, adverse effects, cost, administration techniques, and reduction of medication usage. Methods: Seven databases and Google Scholar were searched up to April 27, 2017, using MeSH descriptors for three overarching themes (ear acupuncture, pain management, and emergency medicine)...
October 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/29060962/-clinical-analysis-of-19-pregnancies-complicated-listeriosis
#20
L H Kuang, Y H Gong, M Su, Y M Jiang
Objective: To analyze the clinical characteristics and perinatal outcomes of listeriosis during pregnancy. Methods: From July 2010 to April 2017, 70 131 women delivered in West China Second University Hospital. Nineteen cases were confirmed as listeriosis. The clinical symptoms, laboratory results, pathogens, placenta pathology and perinatal outcomes were analyzed retrospectively. Results: The median age of the 19 cases was 29.7 (19.0-42.0) years old. The median time before diagnosis was 4.8(0.5-19.0) days...
October 25, 2017: Zhonghua Fu Chan Ke za Zhi
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