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https://www.readbyqxmd.com/read/29889958/surgery-at-sea-the-effect-of-simulated-high-sea-states-on-surgical-performance
#1
Eric Pierce, Renato Rapada, Penelope Anne Herder, Anthony J LaPorta, Tuan N Hoang, Mathew Pena, Jeff Blankenship, Jeff Kiser, Sarah Ashley Catlin
BACKGROUND: The US Navy initiated design concepts for a Medical Mission Module Support Container (M3SC), a mobile operating room capable of rapid installation aboard maneuverable ships within proximity of active combat units. The M3SC provides an alternative echelon of care in the current trauma system by decreasing the time between point of injury, arrival, and surgical intervention. The mobile ships used as M3SC platforms, however, are more susceptible to oceanic conditions that can induce detrimental physiologic motion sickness in medical personnel and patients aboard the vessels...
2018: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/29888377/the-future-of-diving-research-in-norway
#2
EDITORIAL
Andreas Møllerløkken
Norway has a long tradition of quality research within the field of baromedicine. With the discovery of oil in the North Sea, it became important to establish scientific research facilities to overcome immediate challenges, but also to work towards long-term goals. For the diving community, an understanding of the pathophysiology of decompression sickness (DCS) has been one of the major forces to maintain focus on the importance of scientific research in this field. In addition to oil, the aquaculture and fish farming industries are increasing in size and are Norway's second biggest export industry today...
June 30, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/29864382/an-outbreak-of-salmonella-muenchen-after-consuming-sea-turtle-northern-territory-australia-2017
#3
Anthony D K Draper, Christian L James, Joy E Pascall, Kathryn J Shield, Jennifer Langrell, Adrian Hogg
An outbreak of Salmonella Muenchen gastroenteritis occurred in a remote coastal Aboriginal community in the Northern Territory (NT) of Australia. There were 22 people sick (attack rate 55%); 7 had laboratory confirmed S. Muenchen infection; 2 required medical evacuation and admission to the intensive care unit (ICU). We conducted a descriptive case series to investigate the outbreak. All cases ate meat from a single green turtle (Chelonia mydas). The animal's pre-death stress, improper butchering, insufficient cooking and the unsatisfactory storage of meat all likely contributed to the outbreak...
December 1, 2017: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/29782186/excessive-erythrocytosis-and-cardiovascular-risk-in-andean-highlanders
#4
Noemí Corante, Cecilia Anza-Ramírez, Rómulo Figueroa-Mujíca, José Luis Macarlupú, Gustavo Vizcardo-Galindo, Grzegorz Bilo, Gianfranco Parati, Jorge L Gamboa, Fabiola León-Velarde, Francisco C Villafuerte
Cardiovascular diseases are the main cause of death worldwide. Life under high-altitude (HA) hypoxic conditions is believed to provide highlanders with a natural protection against cardiovascular and metabolic diseases compared with sea-level inhabitants. However, some HA dwellers become intolerant to chronic hypoxia and develop a progressive incapacitating syndrome known as chronic mountain sickness (CMS), characterized by excessive erythrocytosis (EE; Hb ≥21 g/dL in men, Hb ≥19 g/dL in women). Evidence from HA studies suggests that, in addition to CMS typical signs and symptoms, these highlanders may also suffer from metabolic and cardiovascular disorders...
May 21, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29695441/pulmonary-ventilation-perfusion-mismatch-a-novel-hypothesis-for-how-diving-vertebrates-may-avoid-the-bends
#5
REVIEW
Daniel Garcia Párraga, Michael Moore, Andreas Fahlman
Hydrostatic lung compression in diving marine mammals, with collapsing alveoli blocking gas exchange at depth, has been the main theoretical basis for limiting N2 uptake and avoiding gas emboli (GE) as they ascend. However, studies of beached and bycaught cetaceans and sea turtles imply that air-breathing marine vertebrates may, under unusual circumstances, develop GE that result in decompression sickness (DCS) symptoms. Theoretical modelling of tissue and blood gas dynamics of breath-hold divers suggests that changes in perfusion and blood flow distribution may also play a significant role...
April 25, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29673435/decompression-sickness-in-the-f-a-18c-after-atypical-cabin-pressure-fluctuations
#6
Katherine J Lee, Aliye Z Sanou
BACKGROUND: The spectrum of altitude decompression sickness (DCS) is evolving as more cases of atypical pressure fluctuations occur. This ongoing change makes it a difficult condition to diagnose and even more difficult to identify. Both Flight Surgeons and Undersea Medical Officers (UMOs) must keep DCS on the differential. These two cases describe altitude DCS after unique pressure patterns, with one at a markedly lower than expected altitude for DCS. CASE REPORT: Both cases occurred in the F/A-18C and resulted in DCS requiring hyperbaric chamber treatment...
May 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29670534/divergent-mitochondrial-antioxidant-activities-and-lung-alveolar-architecture-in-the-lungs-of-rats-and-mice-at-high-altitude
#7
Alexandra Jochmans-Lemoine, Susana Revollo, Gabriella Villalpando, Ibana Valverde, Marcelino Gonzales, Sofien Laouafa, Jorge Soliz, Vincent Joseph
Compared with mice, adult rats living at 3,600 m above sea level (SL-La Paz, Bolivia) have high hematocrit, signs of pulmonary hypertension, and low lung volume with reduced alveolar surface area. This phenotype is associated with chronic mountain sickness in humans living at high altitude (HA). We tested the hypothesis that this phenotype is associated with impaired gas exchange and oxidative stress in the lungs. We used rats and mice (3 months old) living at HA (La Paz) and SL (Quebec City, Canada) to measure arterial oxygen saturation under graded levels of hypoxia (by pulse oximetry), the alveolar surface area in lung slices and the activity of pro- (NADPH and xanthine oxidases-NOX and XO) and anti- (superoxide dismutase, and glutathione peroxidase-SOD and GPx) oxidant enzymes in cytosolic and mitochondrial lung protein extracts...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29625625/association-of-egln1-genetic-polymorphisms-with-spo-2-responses-to-acute-hypobaric-hypoxia-in-a-japanese-cohort
#8
Yoshiki Yasukochi, Takayuki Nishimura, Midori Motoi, Shigeki Watanuki
BACKGROUND: Recent studies have explored various genetic and physiological factors related to high-altitude adaptation in highlander populations. However, the effects of single nucleotide polymorphisms (SNPs), influencing such adaptation, on physiological responses to hypobaric hypoxia have not been examined in lowlanders with lowlander ancestry. Thus, we aimed to investigate the association between SNPs around the EGLN1 genomic region, possibly involved in high-altitude adaptation, and physiological changes to hypobaric hypoxia exposure in a cohort of Japanese lowlanders...
April 6, 2018: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/29623044/long-term-intermittent-work-at-high-altitude-right-heart-functional-and-morphological-status-and-associated-cardiometabolic-factors
#9
Julio Brito, Patricia Siques, Rosario López, Raul Romero, Fabiola León-Velarde, Karen Flores, Nicole Lüneburg, Juliane Hannemann, Rainer H Böger
Background: Living at high altitude or with chronic hypoxia implies functional and morphological changes in the right ventricle and pulmonary vasculature with a 10% prevalence of high-altitude pulmonary hypertension (HAPH). The implications of working intermittently (day shifts) at high altitude (hypobaric hypoxia) over the long term are still not well-defined. The aim of this study was to evaluate the right cardiac circuit status along with potentially contributory metabolic variables and distinctive responses after long exposure to the latter condition...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29614518/hypobaric-hypoxia-causes-elevated-thrombin-generation-mediated-by-fviii-that-is-balanced-by-decreased-platelet-activation
#10
Cécile H Kicken, Marisa Ninivaggi, Joke Konings, Martijn Moorlag, Dana Huskens, Jasper A Remijn, Saartje Bloemen, Marcus D Lancé, Bas De Laat
INTRODUCTION:  Epidemiological studies suggest that hypobaric hypoxia at high altitude poses a risk for developing venous thromboembolism. The cause of this observed hypercoagulability remains unclear. Therefore, this study aimed to investigate the effect of hypobaric hypoxia at 3,883 m above sea level on thrombin generation and platelet activation. METHODS:  After complying with medical ethical procedures, 18 participants were recruited, of whom 1 had to leave the study prematurely due to mild acute mountain sickness...
May 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29571231/a-case-control-questionnaire-survey-of-decompression-sickness-risk-in-okinawa-divers
#11
Naoko Suzuki, Kazuyoshi Yagishita, Mitsuhiro Enomoto, Yasushi Kojima, Takuya Oyaizu, Masaharu Shibayama, Kazuo Yamamoto
Background: Decompression sickness (DCS) is a rare condition that is often difficult to diagnose in deep-sea divers. Because of this, prevention and early diagnosis are important. In this case-control study, we examined the risk and preventive factors associated with DCS. Methods: Our original questionnaire survey was conducted among 269 recreational divers in Okinawa. Divers who were diagnosed with DCS by a physician (n = 94) were compared with healthy recreational divers (n = 175)...
January 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29553010/-cleanse-or-die-british-naval-hygiene-in-the-age-of-steam-1840-1900
#12
Elise Juzda Smith
This article focuses on the consolidation of naval hygiene practices during the Victorian era, a period of profound medical change that coincided with the fleet's transition from sail to steam. The ironclads of the mid- to late- nineteenth century offered ample opportunities to improve preventive medicine at sea, and surgeons capitalised on new steam technologies to provide cleaner, dryer, and airier surroundings below decks. Such efforts reflected the sanitarian idealism of naval medicine in this period, inherited from the eighteenth-century pioneers of the discipline...
April 2018: Medical History
https://www.readbyqxmd.com/read/29535634/effect-of-shallow-and-deep-scuba-dives-on-heart-rate-variability
#13
Yeonsik Noh, Hugo F Posada-Quintero, Yan Bai, Joseph White, John P Florian, Peter R Brink, Ki H Chon
Prolonged and high pressure diving may lead to various physiological changes including significant alterations of autonomic nervous system (ANS) activity that may be associated with altered physical performance, decompression sickness, or central nervous system oxygen toxicity. Ideally, researchers could elucidate ANS function before, during, and after dives that are most associated with altered function and adverse outcomes. However, we have a limited understanding of the activities of the ANS especially during deeper prolonged SCUBA diving because there has never been a convenient way to collect physiological data during deep dives...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29387446/acetazolamide-reduces-exercise-capacity-following-a-5-day-ascent-to-4559-m-in-a-randomised-study
#14
Arthur R Bradwell, Kimberley Ashdown, Carla Rue, John Delamere, Owen D Thomas, Samuel J E Lucas, Alex D Wright, Stephen J Harris, Stephen D Myers
Objective: To assess whether acetazolamide (Az), used prophylactically for acute mountain sickness (AMS), alters exercise capacity at high altitude. Methods: Az (500 mg daily) or placebo was administered to 20 healthy adults (aged 36±20 years, range 21-77), who were paired for age, sex, AMS susceptibility and weight, in a double-blind, randomised manner. Participants ascended over 5 days to 4559 m, then exercised to exhaustion on a bicycle ergometer, while recording breath-by-breath gas measurements...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29355592/down-regulation-of-inwardly-rectifying-k-currents-in-astrocytes-derived-from-patients-with-monge-s-disease
#15
Wei Wu, Hang Yao, Helen W Zhao, Juan Wang, Gabriel G Haddad
Chronic mountain sickness (CMS) or Monge's disease is a disease in highlanders. These patients have a variety of neurologic symptoms such as migraine, mental fatigue, confusion, dizziness, loss of appetite, memory loss and neuronal degeneration. The cellular and molecular mechanisms underlying CMS neuropathology is not understood. In the previous study, we demonstrated that neurons derived from CMS patients' fibroblasts have a decreased expression and altered gating properties of voltage-gated sodium channel...
March 15, 2018: Neuroscience
https://www.readbyqxmd.com/read/29340152/impact-of-gas-emboli-and-hyperbaric-treatment-on-respiratory-function-of-loggerhead-sea-turtles-caretta-caretta
#16
Cyril Portugues, Jose Luis Crespo-Picazo, Daniel García-Párraga, Jordi Altimiras, Teresa Lorenzo, Alicia Borque-Espinosa, Andreas Fahlman
Fisheries interactions are the most serious threats for sea turtle populations. Despite the existence of some rescue centres providing post-traumatic care and rehabilitation, adequate treatment is hampered by the lack of understanding of the problems incurred while turtles remain entrapped in fishing gears. Recently it was shown that bycaught loggerhead sea turtles ( Caretta caretta ) could experience formation of gas emboli (GE) and develop decompression sickness (DCS) after trawl and gillnet interaction. This condition could be reversed by hyperbaric O2 treatment (HBOT)...
2018: Conservation Physiology
https://www.readbyqxmd.com/read/29211382/rebel-heart-how-an-elite-team-of-air-force-pararescuemen-saved-a-sick-baby-a-thousand-miles-out-at-sea
#17
Kevin Grange
No abstract text is available yet for this article.
March 2017: JEMS: a Journal of Emergency Medical Services
https://www.readbyqxmd.com/read/29172727/objective-versus-self-reported-sleep-quality-at-high-altitude
#18
Paul J Anderson, Christina M Wood-Wentz, Kent R Bailey, Bruce D Johnson
Anderson, Paul J., Christina M. Wood-Wentz, Kent R. Bailey, and Bruce D. Johnson. Objective versus self-reported sleep quality at high altitude. High Alt Med Biol. 16:000-000, 2017. BACKGROUND: Previous studies have found little relationship between polysomnography and a diagnosis of acute mountain sickness (AMS) using the Lake Louise Symptom Questionnaire (LLSQ). The correlation between sleep question responses on the LLSQ and polysomnography results has not been explored. We compared LLSQ sleep responses and polysomnography data from our previous study of workers rapidly transported to the South Pole...
November 27, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29157337/simulated-high-altitude-helium-oxygen-diving
#19
Lu Shi, Yan-Meng Zhang, Katsuura Tetsuo, Zhong-Yuan Shi, Yi-Qun Fang, Petar J Denoble, Yang-Yang Li
BACKGROUND: Experience with commercial heliox diving at high altitude is limited. The purpose of this study was to evaluate the effects of acute high-altitude exposure on fitness to dive and the safety of decompression after heliox diving while using U.S. Navy heliox decompression tables with Cross correction. METHOD: Four professional male divers were consecutively decompressed in a hypo- and hyperbaric chamber to altitudes of 3000 m (9842.5 ft), 4000 m (13,123...
December 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29051628/deadly-acute-decompression-sickness-in-risso-s-dolphins
#20
A Fernández, E Sierra, J Díaz-Delgado, S Sacchini, Y Sánchez-Paz, C Suárez-Santana, M Arregui, M Arbelo, Y Bernaldo de Quirós
Diving air-breathing vertebrates have long been considered protected against decompression sickness (DCS) through anatomical, physiological, and behavioural adaptations. However, an acute systemic gas and fat embolic syndrome similar to DCS in human divers was described in beaked whales that stranded in temporal and spatial association with military exercises involving high-powered sonar. More recently, DCS has been diagnosed in bycaught sea turtles. Both cases were linked to human activities. Two Risso's dolphin (Grampus griseus) out of 493 necropsied cetaceans stranded in the Canary Islands in a 16-year period (2000-2015), had a severe acute decompression sickness supported by pathological findings and gas analysis...
October 19, 2017: Scientific Reports
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