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https://www.readbyqxmd.com/read/29161747/a-functional-mri-exploration-of-hamstring-activation-during-the-supine-bridge-exercise
#1
Matthew Bourne, Morgan Williams, Tania Pizzari, Anthony Shield
The single leg supine bridge (SLB) is a commonly employed strengthening exercise and is used as a clinical test for hamstring function in sports, however, little is known about the patterns of muscle activation in this task. To explore these activation patterns, nine healthy, recreationally active males underwent functional magnetic resonance imaging (fMRI) of their thighs at rest and immediately after 5 sets of 10 repetitions of the SLB exercise. Exercise-induced increases in the transverse (T2) relaxation time of the biceps femoris long and short heads, semitendinosus and semimembranosus, were determined via signal intensity changes in pre- and post-exercise images and used as an index of muscle activation...
November 21, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29161719/palmitic-acid-curcumin-ester-facilitates-protection-of-neuroblastoma-against-oligomeric-a%C3%AE-40-insult
#2
Zhangyang Qi, Meihao Wu, Yun Fu, Tengfei Huang, Tingting Wang, Yanjie Sun, Zhibo Feng, Changzheng Li
BACKGROUND/AIMS: The generation of reactive oxygen species (ROS) caused by amyloid-β (Aβ) is considered to be one of mechanisms underlying the development of Alzheimer's disease. Curcumin can attenuate Aβ-induced neurotoxicity through ROS scavenging, but the protective effect of intracellular curcumin on neurocyte membranes against extracellular Aβ may be compromised. To address this issue, we synthesized a palmitic acid curcumin ester (P-curcumin) which can be cultivated on the cell membrane and investigated the neuroprotective effect of P-curcumin and its interaction with Aβ...
November 20, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29161676/hydrophilic-and-positively-charged-polyethylenimine-functionalized-mesoporous-magnetic-clusters-for-highly-efficient-removal-of-pb-ii-and-cr-vi-from-wastewater
#3
Min Young Lee, Ji Hwan Lee, Jae Woo Chung, Seung-Yeop Kwak
We develop mesoporous magnetic clusters (MMCs) functionalized with hydrophilic branched polyethylenimine (b-PEI), later called b-MG, and MMCs functionalized with positively charged b-PEI (p-MG). These materials efficiently remove Pb(II) and Cr(VI) from wastewater. Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, thermogravimetric analysis, and nitrogen adsorption-desorption analysis results clearly indicate that hydrophilic b-PEI and positively charged b-PEI are successfully attached to the MMC surfaces...
November 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29161673/reduced-resting-state-thalamostriatal-functional-connectivity-is-associated-with-excessive-daytime-sleepiness-in-persons-with-and-without-depressive-disorders
#4
David T Plante, Rasmus M Birn, Erin C Walsh, Roxanne M Hoks, M Daniela Cornejo, Heather C Abercrombie
BACKGROUND: Excessive daytime sleepiness (EDS) is a common and significant problem encountered in affective illness, however, the biological underpinnings of EDS in persons with psychiatric disorders are not clear. This study evaluated the associations between thalamic connectivity with cortical and subcortical brain regions with EDS in persons with and without depressive disorders (DD). METHODS: Resting-state functional connectivity magnetic resonance imaging scans from 67 unmedicated young to middle-aged women with current DD (n = 30), remitted DD (n = 13), and healthy controls (n = 24) were utilized to examine the associations between thalamic connectivity with cortical/subcortical structures and EDS...
November 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29161499/polymerization-of-well-aligned-organic-nanowires-on-a-ferromagnetic-rare-earth-surface-alloy
#5
Mikel Abadía, Maxim Ilyn, Ignacio Piquero-Zulaica, Pierluigi Gargiani, Celia Rogero, Jose Enrique Ortega, Jens Brede
The high reactivity of magnetic substrate toward molecular overlayers has so far inhibited the realization of more sophisticated on-surface reactions thereby depriving these interfaces of a significant class of chemically tailored organics such as graphene nanoribbons, oligonuclear spin-chains, and metal-organic networks. Here, we present a multi-technique characterization of the polymerization of 4,4″-dibromo-p-terphenyl precursors into ordered poly (p-phenylene) arrays on top of the bi-metallic GdAu$_2$ surface alloy...
November 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/29161498/selective-isolation-of-myosin-subfragment-1-with-a-dna-polyoxovanadate-bioconjugate
#6
Qing Chen, Xue Hu, Dan-Dan Zhang, Xuwei Chen, Jian-Hua Wang
The bioconjugation of a polyoxometalate (POMs), i.e., dodecavanadate (V12O32), to DNA strands produces a functional labeled DNA primer, V12O32-DNA. The grafting of DNA primer onto streptavidin-coated magnetic nanoparticles (SVM) obtains a novel composite, V12O32-DNA@SVM. The high binding-affinity of V12O32 with the ATP binding site in myosin subfragment-1 (S1) facilitates favorable adsorption of myosin, with an efficiency of 99.4% when processing 0.1 mL myosin solution (100 μg/mL) using 0.1 mg composite. Myosin adsorption fits Langmuir model, corresponding to a theoretical adsorption capacity of 613...
November 21, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/29161467/continuous-flow-synthesis-of-supported-magnetic-iron-oxide-nanoparticles-for-efficient-isoeugenol-conversion-to-vanillin
#7
María Dolores Marquez, Pepijn Prinsen, Hangkong Li, Kaimin Shih, Antiono Ángel Romero Reyes, Rafael Luque
This work presents the synthesis of iron oxide nanocatalysts supported on mesoporous Al-SBA-15 using a continuous flow set-up. The magnetic solid nanoparticles were tested as catalysts for the oxidative disruption of isoeugenol using hydrogen peroxide as the oxidant, showing all high activity (63-88 % conversion) and fare selectivity to vanillin (44-68 %). The nanoparticles exhibited good magnetic properties, whensynthesized at continuous flow temperatures not exceeding 190 °C, which is important to enable their efficient separation from reaction mixtures...
November 21, 2017: ChemSusChem
https://www.readbyqxmd.com/read/29161359/recurrent-processing-of-contour-integration-in-the-human-visual-cortex-as-revealed-by-fmri-guided-tms
#8
Ya Li, Yonghui Wang, Sheng Li
Contour integration is a critical step in visual perception because it groups discretely local elements into perceptually global contours. Previous investigations have suggested that striate and extrastriate visual areas are involved in this mid-level processing of visual perception. However, the temporal dynamics of these areas in the human brain during contour integration is less understood. The present study used functional magnetic resonance imaging-guided transcranial magnetic stimulation (TMS) to briefly disrupt 1 of 2 visual areas (V1/V2 and V3B) and examined the causal contributions of these areas to contour detection...
November 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29161358/neural-mechanisms-of-episodic-retrieval-support-divergent-creative-thinking
#9
Kevin P Madore, Preston P Thakral, Roger E Beaty, Donna Rose Addis, Daniel L Schacter
Prior research has indicated that brain regions and networks that support semantic memory, top-down and bottom-up attention, and cognitive control are all involved in divergent creative thinking. Kernels of evidence suggest that neural processes supporting episodic memory-the retrieval of particular elements of prior experiences-may also be involved in divergent thinking, but such processes have typically been characterized as not very relevant for, or even a hindrance to, creative output. In the present study, we combine functional magnetic resonance imaging with an experimental manipulation to test formally, for the first time, episodic memory's involvement in divergent thinking...
November 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29161352/delta-rhythm-orchestrates-the-neural-activity-underlying-the-resting-state-bold-signal-via-phase-amplitude-coupling
#10
Saul Jaime, Hong Gu, Brian F Sadacca, Elliot A Stein, Jose E Cavazos, Yihong Yang, Hanbing Lu
Spontaneous ongoing neuronal activity is a prominent feature of the mammalian brain. Temporal and spatial patterns of such ongoing activity have been exploited to examine large-scale brain network organization and function. However, the neurophysiological basis of this spontaneous brain activity as detected by resting-state functional Magnetic Resonance Imaging (fMRI) remains poorly understood. To this end, multi-site local field potentials (LFP) and blood oxygenation level-dependent (BOLD) fMRI were simultaneously recorded in the rat striatum along with local pharmacological manipulation of striatal activity...
November 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29161281/the-administration-of-hydrogen-sulphide-prior-to-ischemic-reperfusion-has-neuroprotective-effects-in-an-acute-stroke-model
#11
Chul-Woong Woo, Jae-Im Kwon, Kyung-Won Kim, Jeong-Kon Kim, Sang-Beom Jeon, Seung-Chae Jung, Choong-Gon Choi, Sang-Tae Kim, Jinil Kim, Su Jeong Ham, Woo-Hyun Shim, Yu Sub Sung, Hyun Kwon Ha, Yoonseok Choi, Dong-Cheol Woo
Emerging evidence has suggested that hydrogen sulfide (H2S) may alleviate the cellular damage associated with cerebral ischemia/reperfusion (I/R) injury. In this study, we assessed using 1H-magnetic resonance imaging/magnetic resonance spectroscopy (1H-MRI/MRS) and histologic analysis whether H2S administration prior to reperfusion has neuroprotective effects. We also evaluated for differences in the effects of H2S treatment at 2 time points. 1H-MRI/MRS data were obtained at baseline, and at 3, 9, and 24 h after ischemia from 4 groups: sham, control (I/R injury), sodium hydrosulfide (NaHS)-30 and NaHS-1 (NaHS delivery at 30 and 1 min before reperfusion, respectively)...
2017: PloS One
https://www.readbyqxmd.com/read/29161194/intraoperative-ultrasound-in-oral-tongue-cancer-resection-feasibility-study-and-early-outcomes
#12
Osama Tarabichi, Vivek Kanumuri, Amy F Juliano, William C Faquin, Mary E Cunnane, Mark A Varvares
The current standard of care in oral tongue cancer surgery is complete resection with a target of 5-mm microscopic clearance at all margins on final pathologic review. While current methods of resection are often successful at determining the mucosal margins of the lesion, they may be limited when attempting to achieve an adequate deep margin. A number of previous studies suggested that ultrasound is superior to manual palpation and other imaging modalities (computed tomography, magnetic resonance imaging) at demarcating the margins of tongue lesions...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29160952/transit-time-mapping-in-the-mouse-brain-using-time-encoded-pcasl
#13
Lydiane Hirschler, Leon P Munting, Artem Khmelinskii, Wouter M Teeuwisse, Ernst Suidgeest, Jan M Warnking, Louise van der Weerd, Emmanuel L Barbier, Matthias J P van Osch
The cerebral blood flow (CBF) is a potential biomarker for neurological disease. However, the arterial transit time (ATT) of the labeled blood is known to potentially affect CBF quantification. Furthermore, ATT could be an interesting biomarker in itself, as it may reflect underlying macro- and microvascular pathologies. Currently, no optimized magnetic resonance imaging (MRI) sequence exists to measure ATT in mice. Recently, time-encoded labeling schemes have been implemented in rats and humans, enabling ATT mapping with higher signal-to-noise ratio (SNR) and shorter scan time than multi-delay arterial spin labeling (ASL)...
November 21, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/29160950/superconductivity-in-a-cu-ii-based-coordination-polymer-with-perfect-kagom%C3%A3-structure
#14
Xing Huang, Shuai Zhang, Liyao Liu, Lei Yu, Genfu Chen, Wei Xu, Daoben Zhu
Highly crystalline material of Copper (II) benzenehexathiolate coordination polymer (Cu-BHT) has been prepared. Its two dimensional kagomè structure has been confirmed by powder x-ray diffraction (PXRD), high-resolution transmission electron microscope (HRTEM) and high-resolution scanning transmission electron microscope (STEM). The as-prepared sample exhibits bulk superconductivity at ~ 0.25 K which is confirmed by the zero resistivity, AC magnetic susceptibility and specific heat measurements. Another diamagnetic transition at ~ 3K suggests that there is a second superconducting phase which may be associated to the single layer or few-layer of Cu-BHT...
November 21, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29160930/brain-responses-to-social-norms-meta-analyses-of-fmri-studies
#15
Oksana Zinchenko, Marie Arsalidou
Social norms have a critical role in everyday decision-making, as frequent interaction with others regulates our behavior. Neuroimaging studies show that social-based and fairness-related decision-making activates an inconsistent set of areas, which sometimes includes the anterior insula, anterior cingulate cortex, and others lateral prefrontal cortices. Social-based decision-making is complex and variability in findings may be driven by socio-cognitive activities related to social norms. To distinguish among social-cognitive activities related to social norms, we identified 36 eligible articles in the functional magnetic resonance imaging (fMRI) literature, which we separate into two categories (a) social norm representation and (b) norm violations...
November 21, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29160917/visualization-of-calcium-phosphate-cement-in-teeth-by-zero-echo-time-1-h-mri-at-high-field
#16
Weiqiang Dou, Simone Mastrogiacomo, Andor Veltien, Hamdan S Alghamdi, X Frank Walboomers, Arend Heerschap
(1) H magnetic resonance imaging (MRI) by a zero echo time (ZTE) sequence is an excellent method to image teeth. Calcium phosphate cement (CPC) materials are applied in the restoration of tooth lesions, but it has not yet been investigated whether they can be detected by computed tomography (CT) or MRI. The aim of this study was to optimize high-field ZTE imaging to enable the visualization of a new CPC formulation implanted in teeth and to apply this in the assessment of its decomposition in vivo. CPC was implanted in three human and three goat teeth ex vivo and in three goat teeth in vivo...
November 21, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/29160888/iron-iii-complexes-of-2-methyl-6-pyrimidin-2-yl-hydrazonomethyl-phenol-as-spin-crossover-molecular-materials
#17
Juan Yuan, Mei-Jiao Liu, Cai-Ming Liu, Hui-Zhong Kou
Four new mononuclear Fe(iii) complexes 1-4 of 2-methyl-6-(pyrimidin-2-yl-hydrazonomethyl)-phenol (H2L) have been synthesized and characterized by magnetic susceptibility measurements and single-crystal X-ray diffraction analysis. Complexes 1-3 are ionic compounds with the formula [Fe(HL)2]X·nsolvent (X = ClO4(-) (1), BF4(-) (2) and Cl(-) (3)), while complex 4 ([Fe(HL)(L)]) is neutral. The central Fe(iii) ion in complexes 1-4 is coordinated by four nitrogen and two oxygen atoms of two Schiff base ligands HL(-) or L(2-), and the coordination geometries of Fe(III) are all distorted octahedral...
November 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29160872/zinc-ii-cobalt-ii-and-manganese-ii-networks-with-phosphoserine-ligand-synthesis-crystal-structures-and-magnetic-and-proton-conductivity-properties
#18
J Vallejo, I R Salcedo, R M P Colodrero, A Cabeza, A Switlicka, J Cano, M Viciano-Chumillas
A series of zinc(ii), cobalt(ii) and manganese(ii) coordination networks with phosphoserine ligand (H3PSer) are synthesized and characterized. Whereas in compounds 1 and 2 with the general formula [M(HPser)]n [M = Zn (1) and Co (2)], the metal(ii) ion presents a tetrahedral geometry, in [Co(HPSer)(H2O)2]n (3) and [Mn(HPSer)(H2O)]n (4), the metal(ii) ions are in a distorted octahedral geometry. The 3D frameworks are formed by inorganic layers built up from MO4 or MO6 polyhedra and phosphate groups. These layers are linked by the carboxylate groups of the phosphoserine ligand...
November 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29160793/a-gal-m%C3%A2%C2%B5s-device-to-evaluate-cell-migratory-response-to-combined-galvano-chemotactic-fields
#19
Shawn Mishra, Maribel Vazquez
Electric fields have been studied extensively in biomedical engineering (BME) for numerous regenerative therapies. Recent studies have begun to examine the biological effects of electric fields in combination with other environmental cues, such as tissue-engineered extracellular matrices (ECM), chemical gradient profiles, and time-dependent temperature gradients. In the nervous system, cell migration driven by electrical fields, or galvanotaxis, has been most recently studied in transcranial direct stimulation (TCDS), spinal cord repair and tumor treating fields (TTF)...
November 21, 2017: Biosensors
https://www.readbyqxmd.com/read/29160739/neural-correlates-of-effort-dependent-and-effort-independent-cognitive-fatigue-components-in-patients-with-multiple-sclerosis
#20
Stefan Spiteri, Thomas Hassa, Dolores Claros-Salinas, Christian Dettmers, Mircea Ariel Schoenfeld
BACKGROUND: Among patients with multiple sclerosis (MS), fatigue is the most commonly reported symptom. It can be subdivided into an effort-dependent (fatigability) and an effort-independent component (trait-fatigue). OBJECTIVE: The objective was to disentangle activity changes associated with effort-independent "trait-fatigue" from those associated with effort-dependent fatigability in MS patients. METHODS: This study employed behavioral measures and functional magnetic imaging to investigate neural changes in MS patients associated with fatigue...
November 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
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