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https://www.readbyqxmd.com/read/29681854/evidence-supports-tradition-the-in-vitro-effects-of-roman-chamomile-on-smooth-muscles
#1
Zsolt Sándor, Javad Mottaghipisheh, Katalin Veres, Judit Hohmann, Tímea Bencsik, Attila Horváth, Dezső Kelemen, Róbert Papp, Loránd Barthó, Dezső Csupor
The dried flowers of Chamaemelum nobile (L.) All. have been used in traditional medicine for different conditions related to the spasm of the gastrointestinal system. However, there have been no experimental studies to support the smooth muscle relaxant effect of this plant. The aim of our research was to assess the effects of the hydroethanolic extract of Roman chamomile, its fractions, four of its flavonoids (apigenin, luteolin, hispidulin, and eupafolin), and its essential oil on smooth muscles. The phytochemical compositions of the extract and its fractions were characterized and quantified by HPLC-DAD, the essential oil was characterized by GC and GC-MS...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29615934/chamazulene-attenuates-ros-levels-in-bovine-aortic-endothelial-cells-exposed-to-high-glucose-concentrations-and-hydrogen-peroxide
#2
Giulia Querio, Susanna Antoniotti, Federica Foglietta, Cinzia M Bertea, Roberto Canaparo, Maria P Gallo, Renzo Levi
Endothelial cells surround the lumen of blood vessels and modulate many physiological processes, including vascular tone, blood fluidity, inflammation, immunity and neovascularization. Many pathological conditions, including hyperglycemia, may alter endothelial function through oxidative stress, leading to impaired nitric oxide bioavailability and to the onset of an inflammatory state. As widely shown in the last decade, dietary intervention could represent a good strategy to control endothelial dysfunction and atherosclerosis...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29615674/acute-metabolic-actions-of-the-major-polyphenols-in-chamomile-an-in-vitro-mechanistic-study-on-their-potential-to-attenuate-postprandial-hyperglycaemia
#3
Jose A Villa-Rodriguez, Asimina Kerimi, Laszlo Abranko, Sarka Tumova, Lauren Ford, Richard S Blackburn, Christopher Rayner, Gary Williamson
Transient hyperglycaemia is a risk factor for type 2 diabetes and endothelial dysfunction, especially in subjects with impaired glucose tolerance. Nutritional interventions and strategies for controlling postprandial overshoot of blood sugars are considered key in preventing progress to the disease state. We have identified apigenin-7-O-glucoside, apigenin, and (Z) and (E)-2-hydroxy-4-methoxycinnamic acid glucosides as the active (poly)phenols in Chamomile (Matricaria recutita) able to modulate carbohydrate digestion and absorption in vitro as assessed by inhibition of α-amylase and maltase activities...
April 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29464801/herbal-medicine-for-depression-and-anxiety-a-systematic-review-with-assessment-of-potential-psycho-oncologic-relevance
#4
REVIEW
K Simon Yeung, Marisol Hernandez, Jun J Mao, Ingrid Haviland, Jyothirmai Gubili
Anxiety and depression are prevalent among cancer patients, with significant negative impact. Many patients prefer herbs for symptom relief to conventional medications which have limited efficacy/side effects. We identified single-herb medicines that may warrant further study in cancer patients. Our search included PubMed, Allied and Complementary Medicine, Embase, and Cochrane databases, selecting only single-herb randomized controlled trials between 1996 and 2016 in any population for data extraction, excluding herbs with known potential for interactions with cancer treatments...
May 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29380567/-metabolic-engineering-of-e-%C3%AE-farnesene-synthase-genes-for-aphid-resistant-genetically-modified-plants
#5
Dianyong Jia, Shiqing Gao, Pengfei Duan, Jibao Chen, Fengxia Tian, Xiudao Yu
Aphids are major agricultural pests that cause significant yield losses of crops each year. (E)-β-farnesene (EβF), as the main component of the aphid alarm pheromones, can interrupt aphid feeding and cause other conspecies in the vicinity to become agitated or disperse from their host plant. Furthermore, EβF can function as a kairomone in attracting aphid predators. EβF synthase genes, which encode enzymes that convert farnesyl diphosphate (FPP) to the acyclic sesquiterpene EβF, have been isolated and characterized from peppermint (Mentha × piperita and Mentha asiatica), Yuzu (Citrus junos), Douglas fir (Pseudotsuga menziesii), sweet wormwood (Artemisia annua) and chamomile (Matricaria recutita), respectively...
January 25, 2018: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/29336372/effects-of-matricaria-chamomilla-extract-on-growth-and-maturation-of-isolated-mouse-ovarian-follicles-in-a-three-dimensional-culture-system
#6
Hamed Shoorei, Arash Khaki, Nava Ainehchi, Mohammad Mehdi Hassanzadeh Taheri, Moloud Tahmasebi, Giti Seyedghiasi, Ziba Ghoreishi, Majid Shokoohi, Amir Afshin Khaki, Sayed Haidar Abbas Raza
BACKGROUND: The aim of this study was to design and assess the effects of hydroalcoholic extract of Matricaria chamomilla (MC) on preantral follicle culture of mouse ovaries in a three-dimensional culture system. METHODS: Isolated preantral follicles were randomly divided into three main groups: the control group containing 10% fetal bovine serum without MC extract (G1), the first experimental group supplemented with 25 μg/ml hydroalcoholic extract of chamomile (G2), and the second experimental group supplemented with 50 μg/ml hydroalcoholic extract of chamomile (G3)...
January 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29280987/anti-inflammatory-and-skin-barrier-repair-effects-of-topical-application-of-some-plant-oils
#7
REVIEW
Tzu-Kai Lin, Lily Zhong, Juan Luis Santiago
Plant oils have been utilized for a variety of purposes throughout history, with their integration into foods, cosmetics, and pharmaceutical products. They are now being increasingly recognized for their effects on both skin diseases and the restoration of cutaneous homeostasis. This article briefly reviews the available data on biological influences of topical skin applications of some plant oils (olive oil, olive pomace oil, sunflower seed oil, coconut oil, safflower seed oil, argan oil, soybean oil, peanut oil, sesame oil, avocado oil, borage oil, jojoba oil, oat oil, pomegranate seed oil, almond oil, bitter apricot oil, rose hip oil, German chamomile oil, and shea butter)...
December 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29258478/pregnancy-prescription-medicines-and-the-potential-risk-of-herb-drug-interactions-a-cross-sectional-survey
#8
James S McLay, Naila Izzati, Abdul R Pallivalapila, Ashalatha Shetty, Binita Pande, Craig Rore, Moza Al Hail, Derek Stewart
BACKGROUND: Pregnant women are routinely prescribed medicines while self-medicating with herbal natural products to treat predominantly pregnancy related conditions. The aim of this study was to assess the potential for herb-drug interactions (HDIs) in pregnant women and to explore possible herb-drug interactions and their potential clinical significance. METHODS: A cross-sectional survey of women during early pregnancy or immediately postpartum in North-East Scotland...
December 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29211364/insights-into-novel-anticancer-applications-for-apigenin
#9
REVIEW
Adam Kowalczyk, Agnieszka Bodalska, Marta Miranowicz, Katarzyna Karłowicz-Bodalska
Flavonoids, naturally occuring derivatives of 2-phenyl-benzo-γ-pyrone, are widespread in plants as coloring substances. Apigenin (4',5,7,-trihydroxyflavone (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), molecular formula C₁₅H₁₀O⁵, is a flavonoid present in many fruits and vegetables, primarily in citrus fruits, apples, parsley and celery leaves. It is also found in some medicinal plants, including chamomile flowers, thyme, oregano, peppermint, lemon balm and yarrow, as a 7-O-glycoside with anti-inflammatory and antioxidant activity...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29193940/-matricaria-chamomilla-aqueous-extract-improves-atopic-dermatitis-like-lesions-in-a-murine-model
#10
Raúl Julián Ortiz-Bautista, Laura Lucelly García-González, Marco Antonio Ocádiz-González, Julia Flores-Tochihuitl, Arturo García-Villaseñor, Margarita González-Hernández, Liliana Muñoz-Hernández, María Del Consuelo Ortiz-Figuero, Marisol Ramírez-Anaya, Silvia Reyna-Téllez, Octavio Villanueva-Sánchez
BACKGROUND: Matricaria Chamomilla L. (Mch), popularly known as chamomile, has been used for centuries as an herbolary remedy due to its broad clinical spectrum. The aim of this study was to evaluate the effect of Mch associated to a vehicle with emollient function in induced atopic dermatitis (AD)-like lesions in a murine model. METHODS: AD was induced with dinitrochlorobenzene on 12 male seven-week old BALB/c mice. Animals were divided in three groups (control, GC; control negative, GCN; and experimental, GE)...
September 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29168225/gaba-modulating-phytomedicines-for-anxiety-a-systematic-review-of-preclinical-and-clinical-evidence
#11
REVIEW
Karen Savage, Joseph Firth, Con Stough, Jerome Sarris
Anxiety disorders are chronic and functionally disabling conditions with high psychological stress, characterised by cognitive symptoms of excessive worry and focus difficulties and physiological symptoms such as muscle tension and insomnia. Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter within the central nervous system and is a key target of pharmacotherapies in the treatment of anxiety. Although current pharmaceutical treatments are often efficacious, they may cause undesirable side effects including cognitive decrements and withdrawal symptoms...
January 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29166929/prevalence-of-dietary-supplement-use-and-associated-factors-among-female-college-students-in-saudi-arabia
#12
Hanan Alfawaz, Nasiruddin Khan, Aziza Alfaifi, Fatima M Shahrani, Huda M Al Tameem, Seetah F Al Otaibi, Weaam I Abudigin, Mohammad S Al-Shayaa, Saad A Al-Ghanim, Nasser M Al-Daghri
BACKGROUND: The economic boom in Saudi Arabia indirectly prompted the use of dietary supplements in the last two decades. Our aim is to investigate the prevalence of dietary supplement use and its association with sociodemographic/lifestyle characteristics among Saudi female students. METHODS: In this cross-sectional study, 534 female participants (≥19 years of age) completed a self-administered questionnaire that include sociodemographic and lifestyle characteristics, perceived health status, dietary supplement use, general awareness, attitudes and behavior...
November 22, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29154070/complementary-and-alternative-therapies-in-dentistry-and-characteristics-of-dentists-who-recommend-them
#13
Beatrice Baatsch, Stefan Zimmer, Daniela Rodrigues Recchia, Arndt Büssing
OBJECTIVES: The aims of this study were to analyse whether dentists offer or recommend complementary and alternative medicine (CAM) remedies in their clinical routine, and how effective these are rated by proponents and opponents. A second aim of this study was to give a profile of the dentists endorsing CAM. DESIGN: A prospective, explorative, anonymised cross-sectional survey was spread among practicing dentists in Germany via congresses, dental periodicals and online (n=250, 55% male, 45% female; mean age 49...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29154054/the-effects-of-chamomile-extract-on-sleep-quality-among-elderly-people-a-clinical-trial
#14
Mohsen Adib-Hajbaghery, Seyedeh Nesa Mousavi
BACKGROUND: The prevalence of insomnia increases with age. Chamomile is among the medicinal plants which are used as tranquilizer. Yet, there is inadequate experimental and clinical evidence regarding its hypnotic effects. This study sought to evaluate the effects of chamomile extract on sleep quality among elderly people. DESIGN: A single-blind randomized controlled trial was performed. SETTING: A convenient sample of sixty elderly people who aged sixty or more and lived in Kahrizak day care nursing home, Karaj, Iran, were randomly allocated to a control and a treatment group...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29080520/an-exploratory-study-of-salivary-cortisol-changes-during-chamomile-extract-therapy-of-moderate-to-severe-generalized-anxiety-disorder
#15
John R Keefe, Wensheng Guo, Qing S Li, Jay D Amsterdam, Jun J Mao
OBJECTIVES: Dysfunctions in stress biology are hypothesized to contribute to anxiety disorders, and to be ameliorated during successful treatment, but limited clinical data exist to support this hypothesis. We evaluated whether increases in morning cortisol and the diurnal cortisol slope, markers of stress biology, are associated with clinical response to chamomile therapy among subjects with generalized anxiety disorder (GAD). METHODS: Among 45 subjects with DSM-IV diagnosed GAD in an open-label clinical trial of chamomile, salivary cortisol was assessed for three days each pre- and post-treatment, at 8am, 12pm, 4pm, and 8pm...
January 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29072514/effectiveness-of-matricaria-chamomilla-chamomile-extract-on-pain-control-of-cyclic-mastalgia-a-double-blind-randomised-controlled-trial
#16
N Saghafi, H Rhkhshandeh, N Pourmoghadam, L Pourali, M Ghazanfarpour, A Behrooznia, F Vafisani
Breast pain (mastalgia) often precedes menstrual period, which is of mild to moderate severity. This study was performed to determine the effectiveness of chamomile on pain control of cyclic mastalgia. This double-blind randomised controlled clinical trial was conducted on 60 patients with mastalgia referred to the breast clinic of an academic hospital, Mashhad University of Medical Sciences. The patients were randomly allocated into two groups: chamomile (n = 30) and placebo (n = 30). Primary outcomes were: (1) assessment of the visual analogue scale (VAS) and (2) assessment of the breast pain chart (BPC) 8 weeks after initial intervention...
January 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29026426/effects-of-nanozeolite-starch-thermoplastic-hydrogels-on-wound-healing
#17
Hossein Salehi, Mohammad Mehrasa, Bijan Nasri-Nasrabadi, Mohsen Doostmohammadi, Reihaneh Seyedebrahimi, Navid Davari, Mohammad Rafienia, Mehdi E Hosseinabadi, Maria Agheb, Mansour Siavash
BACKGROUND: Wound healing is a complex biological process. Some injuries lead to chronic nonhealing ulcers, and healing process is a challenge to both the patient and the medical team. We still look forward an appropriate wound dressing. MATERIALS AND METHODS: In this study, starch-based nanocomposite hydrogel scaffolds reinforced by zeolite nanoparticles (nZ) were prepared for wound dressing. In addition, a herbal drug (chamomile extract) was added into the matrix to accelerate healing process...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28930236/antibacterial-and-antifungal-activity-of-essential-oils-against-pathogens-responsible-for-otitis-externa-in-dogs-and-cats
#18
Valentina V Ebani, Simona Nardoni, Fabrizio Bertelloni, Basma Najar, Luisa Pistelli, Francesca Mancianti
Background: Essential oils (EOs) are recommended by some veterinarians to treat otitis externa in pets, but data about their efficacy in scientific literature are very scant. Methods: Nine commercial EOs, from roman chamomile (Anthemis nobilis L.), star anise (Illicium verum), lavender (Lavandula hybrida), litsea (Litsea cubeba (Lour.) Pers.), basil (Ocimum basilicum L.), oregano (Origanum vulgare L. subsp. hirticum), rosemary (Rosmarinus officinalis L.), clary sage (Salvia sclarea L.), and thyme (Thymus vulgaris L...
April 21, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930137/chemical-composition-cytotoxic-apoptotic-and-antioxidant-activities-of-main-commercial-essential-oils-in-palestine-a-comparative-study
#19
Mohammad A Al-Tamimi, Bob Rastall, Ibrahim M Abu-Reidah
Background: Essential oils (EOs) are complex mixtures of several components gifted with a wide array of biological activities. The present research was designed to evaluate whether commercial essential oils could be effective by examining their in vitro antioxidant, cytotoxic, and apoptotic properties of nine commercially available EOs in Palestine, namely, African rue, basil, chamomile, fennel, fenugreek, ginger, spearmint, sage, and thyme, and to assure their effective use. Methods: The cytotoxic activity was determined using HT29-19(A) non-muco secreting and HT29-muco secreting (MS) cell lines...
October 25, 2016: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28919332/correlation-of-radical-scavenging-capacity-and-amoebicidal-activity-of-matricaria-recutita-l-asteraceae
#20
Soumaya Hajaji, Ines Sifaoui, Atteneri López-Arencibia, María Reyes-Batlle, Ignacio A Jiménez, Isabel L Bazzocchi, Basilio Valladares, José E Pinero, Jacob Lorenzo-Morales, Hafidh Akkari
Some Acanthamoeba strains are able to cause Granulomatous Amoebic Encephalitis (GAE) and Acanthamoeba keratitis (AK) worldwide because of their pathogenicity. The treatment of Acanthamoeba infections is complicated due to the existence of a highly resistant cyst stage in their life cycle. Therefore, the elucidation of novel sources of anti-Acanthamoeba agents is an urgent need. In the present study, an evaluation of the antioxidant and anti-Acanthamoeba activity of compounds in flower extracts of Tunisian chamomile (Matricaria recutita L...
December 2017: Experimental Parasitology
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