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https://www.readbyqxmd.com/read/28107816/the-time-course-of-erythrocyte-membrane-fatty-acid-concentrations-during-and-after-treatment-of-non-human-primates-with-increasing-doses-of-an-omega-3-rich-phospholipid-preparation-derived-from-krill-oil
#1
Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo, Yong-Fu Xiao
BACKGROUND: A commonly used measure to reflect the intake of the long-chain omega-3 fatty acids EPA and DHA is the omega-3 index, defined as the sum of EPA + DHA as % of total fatty acids in erythrocyte membrane. When the omega-3 index changes it follows that the relative fractions of other fatty acids in the membrane are also changed. In the present study, increasing doses of a preparation of omega-3 rich phospholipids extracted from krill oil were administered orally to non-human primates for 12 weeks and the time course of EPA, DHA and 22 other fatty acids in erythrocytes was determined bi-weekly during treatment and for 8 weeks after cessation of treatment...
January 21, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28105887/light-microscopy-with-a-differential-staining-technique-for-the-characterization-and-discrimination-of-insects-versus-marine-arthropods-in-processed-animal-proteins
#2
Matteo Ottoboni, Marco Tretola, Federica Cheli, Daniela Marchis, Pascal Veys, Vincent Baeten, Luciano Pinotti
The aim of this study was to evaluate the use of light microscopy with a differential staining technique for the discrimination of insect material from marine arthropods - classified as fishmeal. Specifically, three samples of single species insect material, Hermetia illucens (HI), Bombyx mori (BM) and Tenebrio molitor (TM) and two samples of marine arthropods, shrimp material and krill, have been analysed and compared after staining by two reagents to enhance fragment identification. Alizarin Red (AR) and Chlorazol black (CB), which react respectively with calcium salts and chitin, were tested for their potential efficacy in distinguishing between insect and marine materials...
January 20, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28095913/effects-of-a-purified-krill-oil-phospholipid-rich-in-long-chain-omega-3-fatty-acids-on-cardiovascular-disease-risk-factors-in-non-human-primates-with-naturally-occurring-diabetes-type-2-and-dyslipidemia
#3
Petter-Arnt Hals, Xiaoli Wang, Yong-Fu Xiao
BACKGROUND: High serum levels of cholesterol, in particular low-density lipoprotein cholesterol, are considered a significant risk factor for development of cardiovascular disease. Therefore, rigorous treatment regimens with statins and other pharmaceuticals have been used extensively to reduce elevated cholesterol levels. Literature data have not clearly concluded whether long-chain omega-3 fatty acids reduce, increase or leave circulating cholesterol unaffected. In the present study a novel krill-oil derived preparation of omega-3 rich phospholipids, mainly phosphatidylcholine, was administered orally at increasing doses for 12 weeks to dyslipidemic non-human primates, and cholesterols and several other risk factors for cardiovascular disease were measured before, during and after treatment...
January 17, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28078684/characterization-of-protease-and-effects-of-temperature-and-salinity-on-the-biochemical-changes-during-fermentation-of-antarctic-krill
#4
Yan Fan, Lili Tian, Yong Xue, Zhaojie Li, Hu Hou, Changhu Xue
BACKGROUND: Despite their abundance, the Antarctic krill are underutilized for numerous difficulties in commercial processing. Ideally, fermentation technology can be applied to transform them into a popular condiment. Besides the exploration on protease properties, this study aimed to evaluate proteinase activities, pH of the fermentation broth, amino nitrogen, and histamine formed during fermentation at different temperatures and salt treatments. RESULTS: Even though activity of the Antarctic krill protease reached a maximum at 40 °C and pH 7, it was stable at 30 °C and pH 7-9...
January 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28078500/effects-of-different-omega-3-sources-fish-oil-krill-oil-and-green-lipped-mussel-against-cytokine-mediated-canine-cartilage-degradation
#5
Kittisak Buddhachat, Puntita Siengdee, Siriwadee Chomdej, Kumpanart Soontornvipart, Korakot Nganvongpanit
Our purpose was to evaluate the protective effect of three marine omega-3 sources, fish oil (FO), krill oil (KO), and green-lipped mussel (GLM) against cartilage degradation. Canine cartilage explants were stimulated with either 10 ng/mL interleukin-1β (IL-1β) or IL-1β/oncostatin M (10 ng/mL each) and then treated with various concentrations of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA; 3 and 30 μg/mL), FO, KO, or GLM (250, 500, and 1000 μg/mL) for 28 days. Gene expression was then investigated in primary canine chondrocytes...
January 11, 2017: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/28068152/effect-of-exposure-type-and-timing-of-injuries-in-division-i-college-football-a-4-year-single-program-analysis
#6
Michael K Krill, James R Borchers, Joshua T Hoffman, Rachel L Tatarski, Timothy E Hewett
BACKGROUND: Football players compete with a high risk of injury due to the sport. With the recent efforts to improve safety, the National Collegiate Athletic Association (NCAA) established new terminology to clearly define exposure types and reduce the number of high contact exposures. OBJECTIVES: To compare football injury rates (IR) with a focus on game versus practice, time in season of injury, mechanism of injury and utilizing recent exposure types defined by the NCAA (live contact, full-pads and non-contact)...
January 19, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28019085/zinc-rich-oysters-as-well-as-zinc-yeast-and-astaxanthin-enriched-food-improved-sleep-efficiency-and-sleep-onset-in-a-randomized-controlled-trial-of-healthy-individuals
#7
Hitomi Saito, Yoan Cherasse, Rina Suzuki, Makoto Mitarai, Fumitaka Ueda, Yoshihiro Urade
SCOPE: Zinc is an essential mineral that plays an important role in the body. We previously reported that orally feeding zinc-enriched yeast to mice induces non-rapid-eye-movement sleep. In addition, astaxanthin, an antioxidant abundant in seafood such as salmon and krill, is able to chelate minerals and may promote zinc absorption, which in return may also improve sleep. The purpose of our study was to examine the effect of zinc-rich and astaxanthin-containing food on sleep in humans...
December 25, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28005361/lipid-class-specific-quantitative-analysis-of-n-3-polyunsaturated-fatty-acids-in-food-supplements
#8
Laura Kutzner, Annika I Ostermann, Thade Konrad, Dieter Riegel, Stefan Hellhake, Jan Philipp Schuchardt, Nils Helge Schebb
Supplementation products containing n-3 PUFA from marine sources serve a large market. Although the amount of eicosapentaenoic acid and docosahexaenoic acid in the products is provided by the manufacturer, no or little information is available on their lipid pattern. Therefore, we quantitatively analyzed the fatty acid pattern in the lipid fractions triglycerides, phospholipids, ethyl esters, and free fatty acids in supplementation products by means of solid phase extraction and gas chromatography. Twelve products from the European and U...
December 22, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27982753/flexpro-md-a-mixture-of-krill-oil-astaxanthin-and-hyaluronic-acid-suppresses-lipopolysaccharide-induced-inflammatory-cytokine-production-through-inhibition-of-nf-%C3%AE%C2%BAb
#9
Doo Ri Park, Ryeojin Ko, Suk Hyung Kwon, Bokkee Min, Seong Ho Yun, Manh Heun Kim, John Minatelli, Stephen Hill, Soo Young Lee
FlexPro MD(®) (FP-MD), a novel multi-ingredient dietary supplement formulation, has been demonstrated to relieve knee joint pain in humans. However, the mechanisms of action responsible for the activity of FP-MD have not been elucidated. In this study, we show the anti-inflammatory effects of FP-MD in RAW264.7 macrophage cells and mice challenged with lipopolysaccharide (LPS). FP-MD significantly inhibited the mRNA levels of pro-inflammatory cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and IL-1β...
December 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27982752/krill-oil-supplementation-improves-dyslipidemia-and-lowers-body-weight-in-mice-fed-a-high-fat-diet-through-activation-of-amp-activated-protein-kinase
#10
Goowon Yang, Jihyun Lee, Sangsu Lee, Dongyun Kwak, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
Krill oil is a novel, commercially available marine oil rich in long-chain polyunsaturated omega-3 fatty acids, particularly eicosapentaenoic acid and docosahexaenoic acid. Compared with fish oil, the effects of krill oil supplementation on human health and its underlying action mechanisms are currently poorly understood. In the present study, we examined the effect of krill oil supplementation on metabolic parameters of mice fed a high-fat diet (HFD). Krill oil supplementation in mice fed a HFD for 10 weeks resulted in an ∼15% lower body weight gain and a dramatic suppression of hepatic steatosis...
December 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27956865/direct-treatment-of-isada-krill-under-subcritical-water-conditions-to-produce-seasoning-with-shrimp-like-flavour
#11
Intira Koomyart, Hironori Nagamizu, Pramote Khuwijitjaru, Takashi Kobayashi, Hirokazu Shiga, Hidefumi Yoshii, Shuji Adachi
Characterization, sensory evaluation, and astaxanthin stability of isada krill under various subcritical water conditions were investigated to optimize the quality of krill extract and residue for producing food seasoning. Raw krill (82% wet basis moisture content) without additional water was treated in a pressure-resistant vessel for 10 min at a temperature range of 100-240 °C. The yield of water-soluble protein was maximized by treatment at 200 °C and decreased with treatment at higher temperatures. The degradation of large molecules and the concomitant production of small molecules depended on the treatment temperature...
September 2016: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/27916863/lipid-composition-of-oil-extracted-from-wasted-norway-lobster-nephrops-norvegicus-heads-and-comparison-with-oil-extracted-from-antarctic-krill-euphasia-superba
#12
Amaya Albalat, Lauren E Nadler, Nicholas Foo, James R Dick, Andrew J R Watts, Heather Philp, Douglas M Neil, Oscar Monroig
In the UK, the Norway lobster (Nephrops norvegicus) supports its most important shellfish fishery. Nephrops are sold either whole, or as "tails-only" for the scampi trade. In the "tailing" process, the "head" (cephalothorax) is discarded as waste. A smaller crustacean species, the Antarctic krill Euphasia superba, represents an economically valuable industry, as its extractable oil is sold as a human dietary supplement. The aim of this study was to determine the amount and composition of the oil contained in discarded Nephrops heads and to compare its composition to the oil extracted from krill...
December 1, 2016: Marine Drugs
https://www.readbyqxmd.com/read/27898754/genome-wide-association-mapping-of-fusarium-head-blight-resistance-in-wheat-using-genotyping-by-sequencing
#13
Marcio P Arruda, Patrick Brown, Gina Brown-Guedira, Allison M Krill, Carrie Thurber, Keith R Merrill, Bradley J Foresman, Frederic L Kolb
Fusarium head blight (FHB) is one of the most important wheat ( L.) diseases worldwide, and host resistance displays complex genetic control. A genome-wide association study (GWAS) was performed on 273 winter wheat breeding lines from the midwestern and eastern regions of the United States to identify chromosomal regions associated with FHB resistance. Genotyping-by-sequencing (GBS) was used to identify 19,992 single-nucleotide polymorphisms (SNPs) covering all 21 wheat chromosomes. Marker-trait associations were performed with different statistical models, the most appropriate being a compressed mixed linear model (cMLM) controlling for relatedness and population structure...
March 2016: Plant Genome
https://www.readbyqxmd.com/read/27884466/linking-pollutant-exposure-of-humpback-whales-breeding-in-the-indian-ocean-to-their-feeding-habits-and-feeding-areas-off-antarctica
#14
Krishna Das, Govindan Malarvannan, Alin Dirtu, Violaine Dulau, Magali Dumont, Gilles Lepoint, Philippe Mongin, Adrian Covaci
Humpback whales, Megaptera novaeangliae, breeding off la Reunion Island (Indian Ocean) undergo large-scale seasonal migrations between summer feeding grounds near Antarctica and their reproductive winter grounds in the Indian Ocean. The main scope of the current study was to investigate chemical exposure of humpback whales breeding in the Indian Ocean by providing the first published data on this breeding stock concerning persistent organic pollutants (POPs), namely polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), hexachlorocyclohexanes (HCHs), DDT and its metabolites (DDTs), chlordane compounds (CHLs), polybrominated diphenyl ethers (PBDEs), and methoxylated PBDEs (MeO-PBDEs)...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27866569/computed-tomography-in-germany
#15
Roman Pokora, Lucian Krille, Steffen Dreger, Choonsik Lee, Christian Günster, Hajo Zeeb, Maria Blettner
BACKGROUND: In 2001, calculations in models based on atomic bomb survivors indicated that children exposed to ionizing radiation by computed tomography (CT) would be expected to have an increased risk of cancer. This led to the issuance of new recommendations in Germany concerning CT in children. METHODS: We analyzed data from the German pediatric CT cohort study together with data on children from a large general statutory health insurance provider (AOK) in order to characterize the secular trend in the use of CT in Germany...
October 28, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/27862466/role-of-ammonium-in-the-ionization-of-phosphatidylcholines-during-electrospray-mass-spectrometry
#16
Michael D Rush, Richard B van Breemen
RATIONALE: Electrospray mass spectrometry methods for the analysis of phosphatidylcholines (PCs) routinely include ammonium acetate or ammonium formate in the mobile phase. In an effort to justify and optimize the use of these additives, we investigated possible functions of ammonium compounds in the ionization of PCs. METHODS: Because PCs contain a quaternary amine, the role of ammonium in neutralizing the negatively charged phosphate group was investigated by using deuterated ammonium acetate, adjusting the pH, varying the organic solvent composition, and by comparing the additives ammonium acetate, ammonium formate and ammonium bicarbonate...
November 11, 2016: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/27817918/a-randomized-double-masked-placebo-controlled-clinical-trial-of-two-forms-of-omega-3-supplements-for-treating-dry-eye-disease
#17
Laura A Deinema, Algis J Vingrys, Chinn Yi Wong, David C Jackson, Holly R Chinnery, Laura E Downie
PURPOSE: To assess the efficacy of 2 forms of oral long-chain omega-3 (ω-3) essential fatty acid (EFA) supplements, phospholipid (krill oil) and triacylglyceride (fish oil), for treating dry eye disease (DED). DESIGN: Randomized, double-masked, placebo-controlled clinical trial. PARTICIPANTS: This study was conducted at a single site and involved 60 participants with mild to moderate DED who were randomized (1:1:1) to 1 of 3 groups: placebo (olive oil), krill oil, or fish oil supplements...
January 2017: Ophthalmology
https://www.readbyqxmd.com/read/27812046/diversity-and-function-of-the-antarctic-krill-microorganisms-from-euphausia-superba
#18
Xiaoqiu Cui, Guoliang Zhu, Haishan Liu, Guoliang Jiang, Yi Wang, Weiming Zhu
The diversity and ecological function of microorganisms associated with Euphausia superba, still remain unknown. This study identified 75 microbial isolates from E. superba, that is 42 fungi and 33 bacteria including eight actinobacteria. And all the isolates showed NaF tolerance in conformity with the nature of the fluoride krill. The maximum concentration was 10%, 3% and 0.5% NaF for actinobacteria, bacteria and fungi, respectively. The results demonstrated that 82.4% bacteria, 81.3% actinobacteria and 12...
November 4, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27807955/-exposure-to-ionizing-radiation-from-computed-tomography-ct-in-childhood-and-cancer-risk
#19
Emilio Antonio Luca Gianicolo, Roman Pokora, Lucian Krille, Maria Blettner
A recent US cohort study estimated 500 cancer cases attributable to exposure to CT out of 600,000 children aged <15 years who underwent a computed tomography (CT) to head or abdomen. This review synthetizes the evidence on the association between exposure to ionizing radiation through CT and cancer risk. Five cohort studies were identified. Three studies show clear increases in cancer risk among children and adolescents who underwent at least one CT. All studies had methodological limits, among which the lack of an individual level estimate of dose-organ specific absorbed by patient and problems of statistical power...
September 2016: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/27728790/nutrient-cycling-are-antarctic-krill-a-previously-overlooked-source-in-the-marine-iron-cycle
#20
Lavenia Ratnarajah, Andrew R Bowie
Iron limits phytoplankton growth in large areas of the Southern Ocean. A new study shows that Antarctic krill play a crucial role in the recycling of iron in the iron-limited waters.
October 10, 2016: Current Biology: CB
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