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https://www.readbyqxmd.com/read/28294970/krill-oil-in-water-emulsion-protects-against-lipopolysaccharide-induced-proinflammatory-activation-of-macrophages-in-vitro
#1
Gabriel A Bonaterra, David Driscoll, Hans Schwarzbach, Ralf Kinscherf
BACKGROUND: Parenteral nutrition is often a mandatory therapeutic strategy for cases of septicemia. Likewise, therapeutic application of anti-oxidants, anti-inflammatory therapy, and endotoxin lowering, by removal or inactivation, might be beneficial to ameliorate the systemic inflammatory response during the acute phases of critical illness. Concerning anti-inflammatory properties in this setting, omega-3 fatty acids of marine origin have been frequently described. This study investigated the anti-inflammatory and LPS-inactivating properties of krill oil (KO)-in-water emulsion in human macrophages in vitro...
March 15, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28249036/humpback-whale-super-groups-a-novel-low-latitude-feeding-behaviour-of-southern-hemisphere-humpback-whales-megaptera-novaeangliae-in-the-benguela-upwelling-system
#2
Ken P Findlay, S Mduduzi Seakamela, Michael A Meÿer, Stephen P Kirkman, Jaco Barendse, David E Cade, David Hurwitz, Amy S Kennedy, Pieter G H Kotze, Steven A McCue, Meredith Thornton, O Alejandra Vargas-Fonseca, Christopher G Wilke
Southern Hemisphere humpback whales (Megaptera novaeangliae) generally undertake annual migrations from polar summer feeding grounds to winter calving and nursery grounds in subtropical and tropical coastal waters. Evidence for such migrations arises from seasonality of historic whaling catches by latitude, Discovery and natural mark returns, and results of satellite tagging studies. Feeding is generally believed to be limited to the southern polar region, where Antarctic krill (Euphausia superba) has been identified as the primary prey item...
2017: PloS One
https://www.readbyqxmd.com/read/28244496/a-comparison-of-the-rate-of-gastrointestinal-bleeding-in-patients-taking-non-vitamin-k-antagonist-oral-anticoagulants-or-warfarin
#3
David J Cangemi, Timothy Krill, Rick Weideman, Daisha J Cipher, Stuart J Spechler, Linda A Feagins
OBJECTIVES: Early reports suggested that the risk of gastrointestinal bleeding (GIB) was higher for patients on non-vitamin K antagonist oral anticoagulants (NOACs) than for those on warfarin. We compared the incidence of GIB in our patients on NOACs with those on warfarin. METHODS: We used our VA pharmacy database to identify patients taking NOACs (dabigatran, rivaroxaban, and apixaban) or warfarin between January 2011 and June 2015, and used the VistA system to identify those who were hospitalized for GIB...
February 28, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28237569/preparation-and-characterization-of-novel-super-artificial-hair-fiber-based-on-biomass-materials
#4
Lijun Yang, Jing Guo, Sen Zhang, Yumei Gong
A novel super-artificial hair fiber basing on sodium alginate (SA) and Antarctic Krill protein (AKP) was prepared by wet spinning successfully. Such SA/AKP fiber did not only have similar crystalline structure with human hair, but also had super flame resistance and mechanical performance. It should be noted that the whole preparation process was green without any incorporation of non-toxic solution. Moreover, comparing with human hair, the SA/AKP fiber had a lot of unique groove upon the fiber surface, which contributed a lot to excellent hygroscopicity...
February 22, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28237087/e-configuration-structures-of-epa-and-dha-derived-from-euphausia-superba-and-their-significant-inhibitive-effects-on-growth-of-human-cancer-cell-lines-in-vitro
#5
Weilong Zheng, Xudong Wang, Wenjing Cao, Bowen Yang, Ying Mu, Yuesheng Dong, Zhilong Xiu
Many bioactive components such as poly-unsaturated fatty acids (e.g. EPA and DHA), phospholipids and astaxanthin are known in Antarctic krill (Euphausia superba) oil. The krill DHA and EPA are generally considered to be similar to natural ones. However, two chemical compounds which were separated from Antarctic krill oil and identified as EPA and DHA by HRESIMS and NMR acted much more effective inhibitive activities on growth of several cell lines (U937, K562, SMMC-7721, PC-3, MDA-MB-231, HL60 and MCF-7) than those from sturgeon liver and commercial fish oil...
February 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28225825/validation-of-band-counts-in-eyestalks-for-the-determination-of-age-of-antarctic-krill-euphausia-superba
#6
Raouf Kilada, Christian S Reiss, So Kawaguchi, Robert A King, Tsuyoshi Matsuda, Taro Ichii
Using known-age Antarctic krill (Euphausia superba) grown from eggs hatched at two different laboratories, we validate the annual pattern of bands deposited in the eyestalks of krill and determine the absolute age of these animals. Ages two through five years were validated, and these animals ranged from 37.1 to 62.6 mm in total length. The band counts in these individuals were either identical to their absolute ages, or only failed to agree by a few months, which demonstrates the accuracy of this method. Precision and bias were estimated graphically using Chang's index (Coefficient of Variation = 5...
2017: PloS One
https://www.readbyqxmd.com/read/28212295/short-chain-chitin-oligomers-promoters-of-plant-growth
#7
Alexander J Winkler, Jose Alfonso Dominguez-Nuñez, Inmaculada Aranaz, César Poza-Carrión, Katrina Ramonell, Shauna Somerville, Marta Berrocal-Lobo
Chitin is the second most abundant biopolymer in nature after cellulose, and it forms an integral part of insect exoskeletons, crustacean shells, krill and the cell walls of fungal spores, where it is present as a high-molecular-weight molecule. In this study, we showed that a chitin oligosaccharide of lower molecular weight (tetramer) induced genes in Arabidopsis that are principally related to vegetative growth, development and carbon and nitrogen metabolism. Based on plant responses to this chitin tetramer, a low-molecular-weight chitin mix (CHL) enriched to 92% with dimers (2mer), trimers (3mer) and tetramers (4mer) was produced for potential use in biotechnological processes...
February 15, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28193735/comprehensive-genomic-profiling-aids-in-distinguishing-metastatic-recurrence-from-second-primary-cancers
#8
Benjamin A Weinberg, Kyle Gowen, Thomas K Lee, Sai-Hong Ignatius Ou, Robert Bristow, Lauren Krill, M Isabel Almira-Suarez, Siraj M Ali, Vincent A Miller, Stephen V Liu, Samuel J Klempner
BACKGROUND: Metastatic recurrence after treatment for locoregional cancer is a major cause of morbidity and cancer-specific mortality. Distinguishing metastatic recurrence from the development of a second primary cancer has important prognostic and therapeutic value and represents a difficult clinical scenario. Advances beyond histopathological comparison are needed. We sought to interrogate the ability of comprehensive genomic profiling (CGP) to aid in distinguishing between these clinical scenarios...
February 13, 2017: Oncologist
https://www.readbyqxmd.com/read/28187156/krilldb-a-de-novo-transcriptome-database-for-the-antarctic-krill-euphausia-superba
#9
Gabriele Sales, Bruce E Deagle, Enrica Calura, Paolo Martini, Alberto Biscontin, Cristiano De Pittà, So Kawaguchi, Chiara Romualdi, Bettina Meyer, Rodolfo Costa, Simon Jarman
Antarctic krill (Euphausia superba) is a key species in the Southern Ocean with an estimated biomass between 100 and 500 million tonnes. Changes in krill population viability would have catastrophic effect on the Antarctic ecosystem. One looming threat due to elevated levels of anthropogenic atmospheric carbon dioxide (CO2) is ocean acidification (lowering of sea water pH by CO2 dissolving into the oceans). The genetics of Antarctic krill has long been of scientific interest for both for the analysis of population structure and analysis of functional genetics...
2017: PloS One
https://www.readbyqxmd.com/read/28107816/the-time-course-of-erythrocyte-membrane-fatty-acid-concentrations-during-and-after-treatment-of-non-human-primates-with-increasing-doses-of-an-omega-3-rich-phospholipid-preparation-derived-from-krill-oil
#10
Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo, Yong-Fu Xiao
BACKGROUND: A commonly used measure to reflect the intake of the long-chain omega-3 fatty acids EPA and DHA is the omega-3 index, defined as the sum of EPA + DHA as % of total fatty acids in erythrocyte membrane. When the omega-3 index changes it follows that the relative fractions of other fatty acids in the membrane are also changed. In the present study, increasing doses of a preparation of omega-3 rich phospholipids extracted from krill oil were administered orally to non-human primates for 12 weeks and the time course of EPA, DHA and 22 other fatty acids in erythrocytes was determined bi-weekly during treatment and for 8 weeks after cessation of treatment...
January 21, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28105887/light-microscopy-with-a-differential-staining-technique-for-the-characterization-and-discrimination-of-insects-versus-marine-arthropods-in-processed-animal-proteins
#11
Matteo Ottoboni, Marco Tretola, Federica Cheli, Daniela Marchis, Pascal Veys, Vincent Baeten, Luciano Pinotti
The aim of this study was to evaluate the use of light microscopy with a differential staining technique for the discrimination of insect material from marine arthropods - classified as fishmeal. Specifically, three samples of single species insect material, Hermetia illucens (HI), Bombyx mori (BM) and Tenebrio molitor (TM) and two samples of marine arthropods, shrimp material and krill, have been analysed and compared after staining by two reagents to enhance fragment identification. Alizarin Red (AR) and Chlorazol black (CB), which react respectively with calcium salts and chitin, were tested for their potential efficacy in distinguishing between insect and marine materials...
January 20, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28095913/effects-of-a-purified-krill-oil-phospholipid-rich-in-long-chain-omega-3-fatty-acids-on-cardiovascular-disease-risk-factors-in-non-human-primates-with-naturally-occurring-diabetes-type-2-and-dyslipidemia
#12
Petter-Arnt Hals, Xiaoli Wang, Yong-Fu Xiao
BACKGROUND: High serum levels of cholesterol, in particular low-density lipoprotein cholesterol, are considered a significant risk factor for development of cardiovascular disease. Therefore, rigorous treatment regimens with statins and other pharmaceuticals have been used extensively to reduce elevated cholesterol levels. Literature data have not clearly concluded whether long-chain omega-3 fatty acids reduce, increase or leave circulating cholesterol unaffected. In the present study a novel krill-oil derived preparation of omega-3 rich phospholipids, mainly phosphatidylcholine, was administered orally at increasing doses for 12 weeks to dyslipidemic non-human primates, and cholesterols and several other risk factors for cardiovascular disease were measured before, during and after treatment...
January 17, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28078684/characterization-of-protease-and-effects-of-temperature-and-salinity-on-the-biochemical-changes-during-fermentation-of-antarctic-krill
#13
Yan Fan, Lili Tian, Yong Xue, Zhaojie Li, Hu Hou, Changhu Xue
BACKGROUND: Despite their abundance, the Antarctic krill are underutilized for numerous difficulties in commercial processing. Ideally, fermentation technology can be applied to transform them into a popular condiment. Besides the exploration on protease properties, this study aimed to evaluate proteinase activities, pH of the fermentation broth, amino nitrogen, and histamine formed during fermentation at different temperatures and salt treatments. RESULTS: Even though activity of the Antarctic krill protease reached a maximum at 40 °C and pH 7, it was stable at 30 °C and pH 7-9...
January 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28078500/effects-of-different-omega-3-sources-fish-oil-krill-oil-and-green-lipped-mussel-against-cytokine-mediated-canine-cartilage-degradation
#14
Kittisak Buddhachat, Puntita Siengdee, Siriwadee Chomdej, Kumpanart Soontornvipart, Korakot Nganvongpanit
Our purpose was to evaluate the protective effect of three marine omega-3 sources, fish oil (FO), krill oil (KO), and green-lipped mussel (GLM) against cartilage degradation. Canine cartilage explants were stimulated with either 10 ng/mL interleukin-1β (IL-1β) or IL-1β/oncostatin M (10 ng/mL each) and then treated with various concentrations of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA; 3 and 30 μg/mL), FO, KO, or GLM (250, 500, and 1000 μg/mL) for 28 days. Gene expression was then investigated in primary canine chondrocytes...
January 11, 2017: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/28068152/effect-of-exposure-type-and-timing-of-injuries-in-division-i-college-football-a-4-year-single-program-analysis
#15
Michael K Krill, James R Borchers, Joshua T Hoffman, Rachel L Tatarski, Timothy E Hewett
BACKGROUND: Football players compete with a high risk of injury due to the sport. With the recent efforts to improve safety, the National Collegiate Athletic Association (NCAA) established new terminology to clearly define exposure types and reduce the number of high contact exposures. OBJECTIVES: To compare football injury rates (IR) with a focus on game versus practice, time in season of injury, mechanism of injury and utilizing recent exposure types defined by the NCAA (live contact, full-pads and non-contact)...
January 19, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28019085/zinc-rich-oysters-as-well-as-zinc-yeast-and-astaxanthin-enriched-food-improved-sleep-efficiency-and-sleep-onset-in-a-randomized-controlled-trial-of-healthy-individuals
#16
Hitomi Saito, Yoan Cherasse, Rina Suzuki, Makoto Mitarai, Fumitaka Ueda, Yoshihiro Urade
SCOPE: Zinc is an essential mineral that plays an important role in the body. We previously reported that orally feeding zinc-enriched yeast to mice induces non-rapid-eye-movement sleep. In addition, astaxanthin, an antioxidant abundant in seafood such as salmon and krill, is able to chelate minerals and may promote zinc absorption, which in return may also improve sleep. The purpose of our study was to examine the effect of zinc-rich and astaxanthin-containing food on sleep in humans...
December 25, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28005361/lipid-class-specific-quantitative-analysis-of-n-3-polyunsaturated-fatty-acids-in-food-supplements
#17
Laura Kutzner, Annika I Ostermann, Thade Konrad, Dieter Riegel, Stefan Hellhake, Jan Philipp Schuchardt, Nils Helge Schebb
Supplementation products containing n-3 PUFA from marine sources serve a large market. Although the amount of eicosapentaenoic acid and docosahexaenoic acid in the products is provided by the manufacturer, no or little information is available on their lipid pattern. Therefore, we quantitatively analyzed the fatty acid pattern in the lipid fractions triglycerides, phospholipids, ethyl esters, and free fatty acids in supplementation products by means of solid phase extraction and gas chromatography. Twelve products from the European and U...
December 22, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27982753/flexpro-md-a-mixture-of-krill-oil-astaxanthin-and-hyaluronic-acid-suppresses-lipopolysaccharide-induced-inflammatory-cytokine-production-through-inhibition-of-nf-%C3%AE%C2%BAb
#18
Doo Ri Park, Ryeojin Ko, Suk Hyung Kwon, Bokkee Min, Seong Ho Yun, Manh Heun Kim, John Minatelli, Stephen Hill, Soo Young Lee
FlexPro MD(®) (FP-MD), a novel multi-ingredient dietary supplement formulation, has been demonstrated to relieve knee joint pain in humans. However, the mechanisms of action responsible for the activity of FP-MD have not been elucidated. In this study, we show the anti-inflammatory effects of FP-MD in RAW264.7 macrophage cells and mice challenged with lipopolysaccharide (LPS). FP-MD significantly inhibited the mRNA levels of pro-inflammatory cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and IL-1β...
December 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27982752/krill-oil-supplementation-improves-dyslipidemia-and-lowers-body-weight-in-mice-fed-a-high-fat-diet-through-activation-of-amp-activated-protein-kinase
#19
Goowon Yang, Jihyun Lee, Sangsu Lee, Dongyun Kwak, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
Krill oil is a novel, commercially available marine oil rich in long-chain polyunsaturated omega-3 fatty acids, particularly eicosapentaenoic acid and docosahexaenoic acid. Compared with fish oil, the effects of krill oil supplementation on human health and its underlying action mechanisms are currently poorly understood. In the present study, we examined the effect of krill oil supplementation on metabolic parameters of mice fed a high-fat diet (HFD). Krill oil supplementation in mice fed a HFD for 10 weeks resulted in an ∼15% lower body weight gain and a dramatic suppression of hepatic steatosis...
December 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27956865/direct-treatment-of-isada-krill-under-subcritical-water-conditions-to-produce-seasoning-with-shrimp-like-flavour
#20
Intira Koomyart, Hironori Nagamizu, Pramote Khuwijitjaru, Takashi Kobayashi, Hirokazu Shiga, Hidefumi Yoshii, Shuji Adachi
Characterization, sensory evaluation, and astaxanthin stability of isada krill under various subcritical water conditions were investigated to optimize the quality of krill extract and residue for producing food seasoning. Raw krill (82% wet basis moisture content) without additional water was treated in a pressure-resistant vessel for 10 min at a temperature range of 100-240 °C. The yield of water-soluble protein was maximized by treatment at 200 °C and decreased with treatment at higher temperatures. The degradation of large molecules and the concomitant production of small molecules depended on the treatment temperature...
September 2016: Food Technology and Biotechnology
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