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Lymphedema

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https://www.readbyqxmd.com/read/29789187/a-review-of-lymphedema-for-the-hand-and-upper-extremity-surgeon
#1
REVIEW
Assaf A Zeltzer, Alexander Anzarut, Moustapha Hamdi
Secondary lymphedema of the upper limb is frequently seen in Western countries after cancer treatment (most often breast in women). It is a chronic disease that affects quality of life and functioning. In its extreme form, it may be debilitating. A review is given of the pathology, nonsurgical treatment, and surgical treatment with a protocol.
May 19, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29788685/the-lateral-intercostal-artery-perforator-as-an-alternative-donor-vessel-for-free-vascularized-lymph-node-transplantation
#2
Min-Seok Daniel Kwak, Hans-Guenther Machens
Chronic lymphedema is caused by an impairment of the lymphatic system due to primary or secondary causes. Vascularized lymph node transplantation (VLNT) is currently the most promising and frequently used technique besides lymphaticovenous anastomosis. However, the vessel anatomy in the lateral thoracic region is sometimes quite variable. Based on our experiences with vascular anatomical inconstancy in the lateral thoracic region, we planned a lateral intercostal artery perforator flap for VLNT in a female patient with chronic stage II lymphedema of both legs after cervical cancer treatment...
May 2018: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29787421/the-impact-of-saphenous-vein-sparing-during-inguinal-lymphadenectomy-on-postoperative-morbidity-in-women-with-vulval-cancer-an-updated-per-groin-meta-analysis-of-short-term-outcomes
#3
Anastasios Tranoulis, Alexandros Laios, George Theophilou, Konstantinos Bramis, Sean Kehoe
OBJECTIVE: Inguinofemoral lymphadenectomy (IFL) is included in the standard surgical management of early-stage vulval cancer (VC) but is often accompanied by surgical complications. Efforts have been made to limit the postoperative morbidity by adopting more conservative IFL techniques without compromising the surgical outcomes. Saphenous vein (SV) preservation during IFL for VC appears to reduce the incidence of postoperative complications including lymphedema. To ascertain the efficacy of SV preservation, we aimed to revisit the impact of SV preservation on short-term per groin complications by updating on a previous meta-analysis to further guide current clinical practice...
May 22, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29785099/comparison-of-the-effectiveness-of-complex-decongestive-therapy-and-compression-bandaging-as-a-method-of-treatment-of-lymphedema-in-the-elderly
#4
Ewa Zasadzka, Tomasz Trzmiel, Maria Kleczewska, Mariola Pawlaczyk
Background: Lymphedema is a chronic condition which significantly lowers the quality of patient life, particularly among elderly populations, whose mobility and physical function are often reduced. Objectives: The aim of the study was to compare the effectiveness of multi-layer compression bandaging (MCB) and complex decongestive therapy (CDT), and to show that MCB is a cheaper, more accessible and less labor intensive method of treating lymphedema in elderly patients...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29774452/lymphedema-following-cancer-therapy-overview-and-options
#5
Michael Bernas, Saskia R J Thiadens, Betty Smoot, Jane M Armer, Paula Stewart, Jay Granzow
This summit focusing on lymphedema following cancer therapy was held during the 7th International Symposium on Cancer Metastasis through the Lymphovascular System. It was unique for the inclusion of patients with lymphedema joining physicians, therapists, healthcare professionals, and researchers to highlight what is known and more importantly what is unknown about the current state of research and treatment in the United States. The session opened with an introduction to lymphedema and then explored the incidence of multiple cancer-related lymphedemas, imaging tools and techniques useful for the diagnosis of lymphatic system abnormalities, and the new findings concerning the genetics of cancer-related lymphedema...
May 17, 2018: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/29773802/cd4-t-cells-are-activated-in-regional-lymph-nodes-and-migrate-to-skin-to-initiate-lymphedema
#6
Gabriela D García Nores, Catherine L Ly, Daniel A Cuzzone, Raghu P Kataru, Geoffrey E Hespe, Jeremy S Torrisi, Jung Ju Huang, Jason C Gardenier, Ira L Savetsky, Matthew D Nitti, Jessie Z Yu, Sonia Rehal, Babak J Mehrara
T cell-mediated responses have been implicated in the development of fibrosis, impaired lymphangiogenesis, and lymphatic dysfunction in secondary lymphedema. Here we show that CD4+ T cells are necessary for lymphedema pathogenesis by utilizing adoptive transfer techniques in CD4 knockout mice that have undergone tail skin and lymphatic excision or popliteal lymph node dissection. We also demonstrate that T cell activation following lymphatic injury occurs in regional skin-draining lymph nodes after interaction with antigen-presenting cells such as dendritic cells...
May 17, 2018: Nature Communications
https://www.readbyqxmd.com/read/29762243/primary-congenital-lymphedema
#7
Lubomir Mrhac, Kamil Bukovansky, Jana Kafkova, Otakar Kraft
We present the case of a 26-year-old man with congenital primary lymphedema. A lymphedema of the right upper limb appeared at the age of 2 years, followed by edemas of the right lower limb and of the right part of the head and neck. A lymphedema of the left lower limb began 5 years ago, and finally an edema of the external genitalia began 2 years ago. Lymphoscintigraphy of the lower limbs and pelvic/abdominal region (including SPECT/ldCT) revealed interesting abnormalities.
May 14, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29757069/accuracy-of-a-single-measurement-site-for-self-monitoring-of-patients-with-breast-cancer-at-risk-for-lymphedema
#8
Janine T Hidding, Carien H G Beurskens, Marijke T De Vries, Maria W G Nijhuis-van der Sanden, Hanneke W M van Laarhoven, Philip J van der Wees
PURPOSE: Early detection of breast cancer-related lymphedema through simple self-monitoring techniques may lead to early treatment and improved outcomes. METHODS: Prospective study of circumference measurements at four time points before, during, and after adjuvant chemotherapy with docetaxel, doxorubicin, and cyclophosphamide. Volume was calculated using the 10-cm interval circumference measurement method (reference test) and percentage difference between arms, for volume and circumference, was determined...
May 14, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29756392/successful-treatment-of-severe-facial-lymphedema-by-lymphovenous-anastomosis
#9
Yusuke Inatomi, Sei Yoshida, Kenichi Kamizono, Masuo Hanada, Ryuji Yasumatsu, Hideki Kadota
BACKGROUND: Facial edema is a common complication after neck dissection and/or chemoradiotherapy for head and neck cancer. Edema subsides spontaneously in most cases but sometimes persists, in which case surgical intervention is required. We report a case of severe facial edema that showed significant improvement upon lymphovenous anastomosis (LVA). METHODS: A 66-year-old man with oral floor cancer developed progressive facial lymphedema after tumor resection, bilateral neck dissections, chemoradiotherapy, and fibular and rectus abdominis musculocutaneous flap transfer...
May 13, 2018: Head & Neck
https://www.readbyqxmd.com/read/29753301/the-recipient-venule-in-supermicrosurgical-lymphaticovenular-anastomosis-flow-dynamic-classification-and-correlation-with-surgical-outcomes
#10
Giuseppe Visconti, Marzia Salgarello, Akitatsu Hayashi
BACKGROUND:  Venules have been usually neglected in the literature on lymphaticovenular anastomosis (LVA). The aim of this study was to analyze the flow dynamic of recipient venules in LVA and their impact on the surgical outcomes. PATIENTS AND METHODS:  Data from 128 patients affected by extremity lymphedema, who underwent LVA, were collected in two institutions from August 2014 to May 2016. Recipient venules were classified according to their flow dynamic into backflow, slack, and outlet (BSO classification)...
May 12, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29752013/-lymphedema-in-patients-treated-with-sirolimus-15-cases
#11
C Fourgeaud, L Simon, B Benoughidane, S Vignes
BACKGROUND: Sirolimus is a mammalian target of rapamycin (mTOR) inhibitor used after organ transplantation and to treat vascular malformations. Among its adverse effects, limb lymphedema has been described. OBJECTIVE: The aim of this study was to analyze the clinical features, lymphoscintigraphy and lymphedema outcome in patients treated with sirolimus. PATIENTS AND METHODS: Monocentric retrospective study from January 2008 to September 2017 analyzing all consecutive patients having lymphedema occurring with sirolimus...
May 8, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29743947/nursing-intervention-in-women-who-developed-lymphedema-after-undergoing-a-modified-radical-mastectomy-a-pre-experimental-study
#12
Gloria Daniela de la Borbolla Martínez, Martha Elena Huitzache Martínez, Nicolás Padilla Raygoza
The aim of this study was to analyse the effect of a nursing intervention in increasing the therapeutic self-care demand in patients with breast cancer-related lymphedema after a mastectomy. The pre-experiment was carried out on women in the State Cancer Institute in Colima, Mexico. Thirty women who had undergone a mastectomy were included in this study. Each woman received a nursing intervention to increase her knowledge, skills and motivation, which are the components of therapeutic self-care demand. Students' t and P values were calculated for paired means, and the McNemar X2 test was performed for paired categorical variables...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29742039/lymphedema-or-rather-end-of-life-edema
#13
Tomasz Gradalski, Katarzyna Ochalek, Dorota Rybak
No abstract text is available yet for this article.
May 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29740586/supermicrosurgery-history-applications-training-and-the-future
#14
Ido Badash, Daniel J Gould, Ketan M Patel
Supermicrosurgery, a technique of dissection and anastomosis of small vessels ranging from 0.3 to 0.8 mm, has revolutionized the fields of lymphedema treatment and soft tissue reconstruction. The technique offers several distinct benefits to microsurgeons, including the ability to manipulate small vessels that were previously inaccessible, and to minimize donor-site morbidity by dissecting short pedicles in a suprafascial plane. Thus, supermicrosurgery has become increasingly popular in recent years, and its applications have greatly expanded since it was first introduced 20 years ago...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29731936/pretibial-located-stewart-treves-syndrome-uncommon-presentation-in-a-bulgarian-patient
#15
Georgi Tchernev, Irina Yungareva, Hristo Mangarov, Konstantin Stavrov, Ilia Lozev, Ivanka Temelkova, Svetoslav Chernin, Ivan Pidakev, Michael Tronnier
BACKGROUND: The Stewart-Treves syndrome with localisation in the region of the lower extremities is not something unusual as clinical pathology, but the clinical diagnostics is rather difficult, and it can be further complicated maximally because of: the similar locoregional findings in patients with other cutaneous malignancies. CASE REPORT: Presented is a rare form of an epithelioid variant of the Stewart Treves syndrome in a woman, aged 81, localised in the region of the lower leg and significantly advanced only for 2 months...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29730734/robotic-assisted-inguinal-lymphadenectomy-a-systematic-review
#16
REVIEW
Ioannis D Gkegkes, Evelyn Eleni Minis, Christos Iavazzo
BACKGROUND: Lymphadenectomy represents the standard treatment for various types of cancer. The introduction of robotics in lymph node dissection may have an important impact on post-lymphadenectomy complications. METHODS: A systematic literature review was performed. RESULTS: In our review, robotic inguinal lymphadenectomy was performed on 51 patients. Penile squamous cell carcinoma was the most common histological type of the primary neoplasia...
May 5, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29728629/near-infrared-fluorescence-imaging-directly-visualizes-lymphatic-drainage-pathways-and-connections-between-superficial-and-deep-lymphatic-systems-in-the-mouse-hindlimb
#17
Yukari Nakajima, Kimi Asano, Kanae Mukai, Tamae Urai, Mayumi Okuwa, Junko Sugama, Toshio Nakatani
Since lymphedema rarely develops in the mouse hindlimb, the underlying mechanisms remain unclear. We herein investigated the resolution of chronic hindlimb lymphedema in mice using a Near-Infrared Fluorescence (NIRF) imaging system. Nineteen 7-28-week-old BALB/c male and female mice were injected with two dyes for lymphography and dissection. Lymphadenectomy was performed on six male mice to completely obstruct lymph flow in the hindlimb. Edematous changes in both hindlimbs were compared until 60 days after surgery...
May 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29727305/improving-aesthetic-outcomes-after-head-and-neck-reconstruction
#18
Ayham Al Afif, H Kendal Uys, S Mark Taylor
PURPOSE OF REVIEW: Tremendous advancements have been made in head and neck reconstruction following oncologic resection. Despite this, many patients are left with disfiguring postoperative changes. The focus of this review highlights various techniques aimed at improving aesthetic outcomes following head and neck cancer therapy, with a focus on liposuction and fat augmentation. RECENT FINDINGS: Over the past decade, the use of liposuction in treating lymphedema after head and neck cancer therapy has showed promising results...
May 2, 2018: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29723882/cumulative-experience-in-lymphovenous-anastomosis-for-lymphedema-treatment-the-learning-curve-effect-on-the-overall-outcome
#19
Nicolas Pereira, Yeon Hoon Lee, Youngchul Suh, Dong Hoon Choi, Hyun Suk Suh, Jae Yong Jeon, Joon Pio Jp Hong
BACKGROUND:  The lymphovenous anastomosis (LVA) has become one of the treatment options for lymphedema. However, it is regarded as a difficult surgery that many young microsurgeons are reluctant to try. This report investigates the learning curve in regard to symptom improvement. METHOD:  This is a retrospective analysis performed in 33 consecutive lymphedema patients (38 extremities) who underwent only LVAs from August 2010 to February 2016. Surgical outcomes in regard to surgeon's experience were evaluated...
May 3, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29723583/psychometric-development-of-the-upper-limb-lymphoedema-questionnaire-demonstrated-the-patient-reported-outcome-measure-to-be-a-robust-measure-for-breast-cancer-related-lymphoedema
#20
Angela E Williams, Frances Rapport, Ian T Russell, Hayley A Hutchings
OBJECTIVE: To develop and undertake initial validation of a patient-reported outcome measure (PROM) to assess health-related quality of life in patients with breast cancer-related upper limb lymphedema (ULL). STUDY DESIGN AND SETTING: We developed and validated the Upper Limb Lymphedema Quality of Life (ULLQoL) scale in two stages: devising the items and pre-testing with patients and clinicians; longitudinal validation to test its psychometric properties - underlying dimensions, internal consistency, test-retest reliability, construct validity, and responsiveness...
April 30, 2018: Journal of Clinical Epidemiology
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