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Lymphedema

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https://www.readbyqxmd.com/read/28453410/does-lymphedema-severity-affect-quality-of-life-simple-question-challenging-answers
#1
Teresa S Lee, Carol M Morris, Sharon A Czerniec, Andrea J Mangion
PURPOSE: Lymphedema can have a negative impact on the function and quality of life (QOL) of patients, but most studies have examined lymphedema as a binary variable, rather than a multidimensional disease that ranges in severity. This study explored the potential impact of lymphedema severity on function and overall QOL. METHODS AND RESULTS: Of the 54 lymphedema patients recruited, 40 reported their most severe swelling to be in a limb. These participants underwent bioimpedance measurement (L-Dex(®)) and completed either the disabilities of the arm, shoulder, and hand (DASH) questionnaire or the lower extremity functional scale (LEFS)...
April 28, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28453383/applications-of-platelet-rich-plasma-in-lymphedema
#2
Eleftherios Spartalis, Christos Damaskos, Antonios Athanasiou, Dimitrios Schizas, Demetrios Moris, Dimitrios Dimitroulis
No abstract text is available yet for this article.
April 28, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28448706/-prognostic-factors-for-post-surgical-complications-in-bone-infection-and-pseudarthrosis
#3
A Cicero-Álvarez, S R León-Hernández, K Gutiérrez-Enríquez, S Zapata-Rivera
Bone infection and nonunion are the main orthopedic and traumatic complications whose treatment remains a challenge because multiple factors are involved in the rate of failures when you try to correct them. Knowing these factors were the problem that caused the research through a prospective longitudinal study of 83 patients of 43.3 ± 16.1 years old. They were treated for aseptic and septic nonunion, osteomyelitis, osteitis, malunion or infected joint replacement. The cases were classified with or without postoperative complications and outcome related to systemic and local factors taken prognostic model Cierny-Mader as factors affecting immune surveillance, metabolism and local vascularization...
September 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28440875/skin-manifestations-among-gata2-deficient-patients
#4
A Polat, M Dinulescu, S Fraitag, S Nimubona, F Toutain, S Jouneau, E Poullot, C Droitcourt, A Dupuy
GATA2 mutations have been identified in various diseases, such as monoMAC syndrome, Emberger syndrome, familial myelodysplastic syndrome, acute myeloid leukemia, and dendritic cell, monocyte, B and NK cell deficiency. These syndromes present a wide range of clinical features, dominated by severe infections and haematological disorders such as myelodysplastic syndrome. Up to 70% of GATA2-mutated patients have dermatological features, mainly genital or extra-genital warts, panniculitis or erythema nodosum, and lymphedema...
April 25, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28436999/clinical-practice-guidelines-on-the-evidence-based-use-of-integrative-therapies-during-and-after-breast-cancer-treatment
#5
REVIEW
Heather Greenlee, Melissa J DuPont-Reyes, Lynda G Balneaves, Linda E Carlson, Misha R Cohen, Gary Deng, Jillian A Johnson, Matthew Mumber, Dugald Seely, Suzanna M Zick, Lindsay M Boyce, Debu Tripathy
Answer questions and earn CME/CNE Patients with breast cancer commonly use complementary and integrative therapies as supportive care during cancer treatment and to manage treatment-related side effects. However, evidence supporting the use of such therapies in the oncology setting is limited. This report provides updated clinical practice guidelines from the Society for Integrative Oncology on the use of integrative therapies for specific clinical indications during and after breast cancer treatment, including anxiety/stress, depression/mood disorders, fatigue, quality of life/physical functioning, chemotherapy-induced nausea and vomiting, lymphedema, chemotherapy-induced peripheral neuropathy, pain, and sleep disturbance...
April 24, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28434105/far-infrared-ray-for-treating-chronic-lower-extremity-lymphedema-with-dermatolymphangioadenitis-a-postoperative-complication-of-gynecological-tumor-resection
#6
Ke Li, Heng Xu, Ning Fei Liu, Parviz Sadigh, Verity Evans, Yi Xin Zhang
PURPOSE: Lower extremity lymphedema is regarded as a relatively common postoperative complication and is often accompanied with dermatolymphangioadenitis (DLA). This study combines clinical assessment and laboratory investigation to explore therapeutic effects of far-infrared radiation (FIR) therapy for chronic lower extremity lymphedema accompanied with DLA, occurring after gynecological tumor resection. METHODS: Patients who met inclusion and exclusion criteria would be enrolled...
April 22, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28431899/validation-of-the-fact-b-4-ul-questionnaire-and-exploration-of-its-predictive-value-in-women-submitted-to-surgery-for-breast-cancer
#7
Juan Alfonso Andrade Ortega, Ana Pilar Millán Gómez, Marisa Ribeiro González, Pilar Martínez Piró, Juan Jiménez Anula, María Belén Sánchez Andújar
INTRODUCTION AND OBJETIVE: The early detection of upper limb complications is important in women operated on for breast cancer. The "FACT-B+4-UL" questionnaire, a specific variant of the Functional Assessment of Cancer Therapy-Breast (FACT-B) is available among others to measure the upper limb function. PATIENTS AND METHODS: The Spanish version of the upper limb subscale of the FACT-B+4 was validated in a prospective cohort of 201 women operated on for breast cancer (factor analysis, internal consistency, test-retest reliability, construct validity and sensitivity to change were determined)...
April 18, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28420899/three-dimensional-imaging-of-lymphatic-system-in-lymphedema-legs-using-interstitial-computed-tomography-lymphography
#8
Kiyoshi Yamada, Akira Shinaoka, Yoshihiro Kimata
As a new trial, we used interstitial computed tomography-lymphography (CT-LG) in 10 patients with lower extremity lymphedema (n=20 limbs) at stage 0, 1, 2, or 3 under the International Society of Lymphology (ISL) classification. In all cases, CT-LG, lymphoscintigraphy, and indocyanine green fluorescence-lymphography (ICG-LG) were performed. In the examination of the ascending level of depicted lymphatic vessels, we measured the diameters of lymphatic vessels detected with CT-LG and conducted an image analysis of dermal backflow of lymph (DB)...
April 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28411704/lymphoscintigraphic-abnormalities-in-the-contralateral-lower-limbs-of-patients-with-unilateral-lymphedema
#9
Camila Alcoforado de Almeida, Esdras Marques Lins, Simone Cristina Soares Brandão, Álvaro Antônio Bandeira Ferraz, Flavia Cristina Morone Pinto, Silvio Romero de Barros Marques
OBJECTIVE: The contralateral limbs of patients with unilateral lymphedema in the lower limbs (LLs) can exhibit abnormal lymphatic circulation, even in the absence of lymphedema. This idea is based on a number of reports that have studied isolated cases using lymphoscintigraphy. It is likely that these patients previously had some form of lymphopathy, and the lymphedema arose after the action of some external factor. However, there are no studies in the literature that adequately assess the asymptomatic contralateral limbs of these patients or address the prevalence and characteristics of the abnormal lymphatic circulation in these limbs...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28410763/correlation-between-upper-limb-volume-and-arterial-and-venous-blood-flow-velocity-in-lymphedema-secondary-to-breast-cancer-treatment
#10
Monique Silva Rezende, Ana Luiza Marsengo, Amanda Apolinário, Vânia Tie Koga Ferreira, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to correlate upper limb volume and arterial and venous blood flow velocity in breast cancer survivors. METHODS: A cross-sectional study was conducted on 30 women with lymphedema and a mean age of 55.60 years (standard deviation = 8.12). For the assessment of upper limb volume, perimetry was performed with measures at 6 points on the limb, which were mathematically calculated as volume. The blood flow velocity of the axillary and brachial arteries and veins were assessed by Doppler ultrasound with a probe at 4 MHz...
April 12, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28406824/ultrasound-assisted-lymphaticovenular-anastomosis-for-the-treatment-of-peripheral-lymphedema
#11
Giuseppe Visconti, Takumi Yamamoto, Nobuko Hayashi, Akitatsu Hayashi
No abstract text is available yet for this article.
February 16, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28405261/blocking-of-the-lymphatic-vessel-in-lymphedema
#12
Hisako Hara, Makoto Mihara
Objective: In this case report, we present a case wherein we observed a blocking of lymphatic vessels in indocyanine green lymphography and found a shrunken lymphatic vessel intraoperatively. Methods: We performed indocyanine green lymphography and lymphaticovenous anastomosis on a 77-year-old woman. She had previously undergone right mastectomy and axillary lymph node dissection accompanied by radiotherapy and chemotherapy for right breast cancer. She noticed swelling in the right upper limb 22 years after the surgery and consulted our hospital...
2017: Eplasty
https://www.readbyqxmd.com/read/28395985/manual-lymphatic-drainage-in-blood-circulation-of-upper-limb-with-lymphedema-after-breast-cancer-surgery
#13
Raquel Michelini Guerero, Lais Mara Siqueira das Neves, Rinaldo Roberto de Jesus Guirro, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to assess blood flow after manual lymphatic drainage (MLD) in women who had received surgery for breast cancer and had post-axillary lymphadenectomy lymphedema. METHODS: Sixteen volunteers (mean age 64 ± 11.44 years) were divided into 2 groups. Those in group 1 received MLD without upper limb elevation, and those in group 2 received MLD with elevation of 30° of the upper limb. Blood flow velocity of the brachial vein and artery were measured using Doppler ultrasound before, immediately after, and 30 minutes after MLD, with and without 30° of upper limb elevation as defined by a random crossover design and an interval (washout) of 7 days...
April 8, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28391397/changes-in-arm-tissue-composition-with-slowly-progressive-weight-lifting-among-women-with-breast-cancer-related-lymphedema
#14
Xiaochen Zhang, Justin C Brown, Electra D Paskett, Babette S Zemel, Andrea L Cheville, Kathryn H Schmitz
BACKGROUND: Studies in breast cancer-related lymphedema (BRCL) have exclusively examined total arm volume, but not the specific tissue composition that contributes to total volume. We evaluated baseline differences in arm tissue composition [fat mass, lean mass, bone mineral content (BMC), and bone mineral density (BMD)] between the affected and unaffected arms in women with BRCL. We compared changes in arm tissue composition and self-reported lymphedema symptoms after 1 year of weight-lifting versus control...
April 8, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28386788/immediate-effects-of-active-exercise-with-compression-therapy-on-lower-limb-lymphedema
#15
Takuya Fukushima, Tetsuya Tsuji, Yufuko Sano, Chieko Miyata, Michiyo Kamisako, Hiroka Hohri, Chikako Yoshimura, Megumi Asakura, Taro Okitsu, Kaori Muraoka, Meigen Liu
PURPOSE: Active exercise with compression therapy (AECT) is a standard treatment for gynecological cancer-related lower-limb lymphedema (LLL) in clinical situations. However, there is insufficient evidence regarding the immediate effects of the use of AECT on LLL. The purpose of this study was to evaluate the immediate effects of AECT on LLL. METHODS: Participants in this randomized controlled crossover trial comprised 23 women with LLL who completed high-load AECT, low-load AECT, and compression-only therapy (CT)...
April 6, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28382512/microsurgery-guided-by-sequential-preoperative-lymphography-using-68-ga-neb-pet-and-mri-in-patients-with-lower-limb-lymphedema
#16
Xiao Long, Jingjing Zhang, Daming Zhang, Chao Gao, Chongwei Chi, Elan Yang, Huadan Xue, Lixin Lang, Gang Niu, Zhaohui Zhu, Fang Li, Xiaoyuan Chen
OBJECTIVE: The popularity of contemporary microsurgical techniques in treatment of lower-limb lymphedema calls for better visualization of the lymphatic system, both preoperatively and intra-operatively. The aim of this prospective study was to investigate the feasibility of a novel combination of (68)Ga-NEB positron emission tomography (PET) with magnetic resonance lymphography (MRL) in evaluating lymphedema and guiding surgical intervention. METHODS: A total of 11 patients (F 9, M 2, age range 29-69 y) with lower-limb lymphedema classified into stage I to III were recruited...
April 5, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28370792/quality-of-life-in-patients-with-primary-and-secondary-lymphedema-in-the-community
#17
Katharina Herberger, Christine Blome, Kristina Heyer, Franziska Ellis, Karl-Christian Münter, Matthias Augustin
Lymphedema is a complex and burdensome medical problem and requires continuous specific therapy. The aim of this cross-sectional study of community lymphedema care in the metropolitan area of Hamburg, Germany, was to evaluate health-related quality of life (QoL) in lymphedema patients. Generic as well as disease-specific health-related QoL was assessed using EQ-5D and FLQA-LK, respectively. Pain was assessed using a visual analogue scale (VAS). About 301 patients (median age of 60.5 years, 90.8% female) with lymphedema of any origin were included...
April 1, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28370317/the-effect-of-prophylactic-lymphovenous-anastomosis-and-shunts-for-preventing-cancer-related-lymphedema-a-systematic-review-and-meta-analysis
#18
REVIEW
Mads G Jørgensen, Navid M Toyserkani, Jens A Sørensen
BACKGROUND: Lymphedema is one of the most dreaded side effects to any cancer treatment involving lymphadenectomy. Progressed lymphedema is adversely complex and currently there is no widely acknowledged curative treatment. Therefore recent focus has shifted to risk reduction and prevention. It has been hypothesized that bypassing lymphatic vessels to veins prophylactically, could minimize the lymphatic dysfunction seen following lymphadenectomy. METHODS: To investigate this possible future treatment modality, we performed a systematic meta-analysis of studies treating patients with prophylactic lymphovenous analysisstomosis (LVA) for the prevention of secondary lymphedema following lymphadenectomy...
March 28, 2017: Microsurgery
https://www.readbyqxmd.com/read/28367439/mr-lymphangiography-a-practical-guide-to-perform-it-and-a-brief-review-of-the-literature-from-a-technical-point-of-view
#19
Francesco Giuseppe Mazzei, Francesco Gentili, Susanna Guerrini, Nevada Cioffi Squitieri, Duccio Guerrieri, Paolo Gennaro, Michele Scialpi, Luca Volterrani, Maria Antonietta Mazzei
We propose a practical approach for performing high-resolution MR lymphangiography (MRL). We shall discuss and illustrate the technical approach for the visualization of lymphatic vessels in patients suffering from lymphedema, how to distinguish lymphatic vessels from veins, and MRL role in supermicrosurgery treatment planning. A brief review of literature, from a technical point of view, is also reported.
2017: BioMed Research International
https://www.readbyqxmd.com/read/28356336/near-infrared-fluorescence-lymphatic-imaging-of-a-toddler-with-congenital-lymphedema
#20
Matthew R Greives, Melissa B Aldrich, Eva M Sevick-Muraca, John C Rasmussen
Primary lymphedema in the pediatric population remains poorly diagnosed and misunderstood due to a lack of information on the causation and underlying anatomy of the lymphatic system. Consequently, therapeutic protocols for pediatric patients remain sparse and with little evidence to support them. In an effort to better understand the causation of primary pediatric lymphedema and to better inform clinical care, we report the use of near-infrared fluorescence lymphatic imaging on the extremities of an alert, 21-month-old boy who presented with unilateral right arm and hand lymphedema at birth...
March 29, 2017: Pediatrics
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