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Lymphedema

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https://www.readbyqxmd.com/read/29329133/cutaneous-angiosarcoma-of-the-eyelid-mimicking-morbihan-disease
#1
Donna C Ferguson, Louise A Mawn, Rami N Al-Rohil
BACKGROUND: Cutaneous angiosarcoma presents clinically in numerous ways, and can be mistaken for a different clinical entity, particularly when arising at unusual anatomic locations such as the eyelid. CASE PRESENTATION: A 57-year-old woman presented with a 1-year history of eyelid swelling. Concurrent imaging was also suggestive of an edematous process. Multiple superficial biopsies showed nonspecific dermal inflammation and interstitial edema. A diagnosis of Morbihan disease (chronic and idiopathic lymphedema of the eyelid) was rendered, and the patient was treated with compression and local therapy without clinical improvement...
January 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29325501/venous-hemodynamics-assessed-with-air-plethysmography-in-legs-with-lymphedema
#2
Kotaro Suehiro, Noriyasu Morikage, Koshiro Ueda, Makoto Samura, Yuriko Takeuchi, Takashi Nagase, Takahiro Mizoguchi, Kaori Nakamura, Kimikazu Hamano
This study was conducted to identify specific abnormalities using the results from air plethysmography in legs with lymphedema. A routine air plethysmography exercise protocol was performed in 31 patients with unilateral leg lymphedema, and the results were compared with those of 53 patients with unilateral great saphenous vein reflux and 15 normal subjects. The venous filling index in legs with lymphedema (2.1 ± 1.2 mL/sec) was smaller than in legs with great saphenous vein reflux (6.4 ± 4.1 mL/sec, p < 0...
January 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29324858/mapping-the-geographical-distribution-of-podoconiosis-in-cameroon-using-parasitological-serological-and-clinical-evidence-to-exclude-other-causes-of-lymphedema
#3
Kebede Deribe, Amuam Andrew Beng, Jorge Cano, Abdel Jelil Njouendo, Jerome Fru-Cho, Abong Raphael Awah, Mathias Esum Eyong, Patrick W Chounna Ndongmo, Emanuele Giorgi, David M Pigott, Nick Golding, Rachel L Pullan, Abdisalan M Noor, Fikre Enquselassie, Christopher J L Murray, Simon J Brooker, Simon I Hay, Peter Enyong, Melanie J Newport, Samuel Wanji, Gail Davey
BACKGROUND: Podoconiosis is a non-filarial elephantiasis, which causes massive swelling of the lower legs. It was identified as a neglected tropical disease by WHO in 2011. Understanding of the geographical distribution of the disease is incomplete. As part of a global mapping of podoconiosis, this study was conducted in Cameroon to map the distribution of the disease. This mapping work will help to generate data on the geographical distribution of podoconiosis in Cameroon and contribute to the global atlas of podoconiosis...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29322088/successful-management-of-persistent-lower-extremity-lymphedema-with-suction-assisted-lipectomy
#4
John P Micha, Dung H Nguyen, Bram H Goldstein
Introduction: Lower-extremity lymphedema is a significant complication attributed to gynecologic cancer surgery, potentially effectuating severe edema and discernible pain. Case report: We report on a patient who developed persistent, lower-extremity lymphedema following her treatment for cervix cancer. Despite repeated efforts to manage the lymphedema with conventional measures, the patient's condition had not markedly improved. Thereafter, she underwent a suction-assisted lipectomy that effectively resolved her symptoms...
February 2018: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29310798/mechanotransduction-in-blood-and-lymphatic-vascular-development-and-disease
#5
Sofia Urner, Molly Kelly-Goss, Shayn M Peirce, Eckhard Lammert
The blood and lymphatic vasculatures are hierarchical networks of vessels, which constantly transport fluids and, therefore, are exposed to a variety of mechanical forces. Considering the role of mechanotransduction is key for fully understanding how these vascular systems develop, function, and how vascular pathologies evolve. During embryonic development, for example, initiation of blood flow is essential for early vascular remodeling, and increased interstitial fluid pressure as well as initiation of lymph flow is needed for proper development and maturation of the lymphatic vasculature...
2018: Advances in Pharmacology
https://www.readbyqxmd.com/read/29310388/lymphedema-secondary-to-idiopathic-occlusion-of-the-subclavian-and-innominate-veins-after-renal-transplantation-a-case-report
#6
Yong Min Kim, Chul Moon, Dong Erk Goo, Soo Bin Park, Ji Woong Park
RATIONALE: Among the causes of swelling in the extremities of renal transplantation patients, secondary lymphedema caused by complete idiopathic obstruction of large veins is rare and may be difficult to diagnose and treat. PATIENT CONCERNS: A 64-year-old man presented with severe edema and pain that occurred suddenly in the right arm. DIAGNOSES: The patient was diagnosed as stage-2 secondary lymphedema caused by idiopathic occlusion of the subclavian and innominate veins...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29309323/a-surgical-approach-to-the-harvest-of-the-vascularized-submandibular-and-submental-lymph-node-flap-the-through-the-gland-dissection-technique
#7
Hideaki Nonomura, Bien-Keem Tan, Pearlie W W Tan, Terence Goh
BACKGROUND: Extremity lymphedema is a pathological condition resulting from absence of lymph nodes and disease of lymphatic vessels, often due to oncologic clearance of lymph nodes. In recent years, vascularized lymph node transfer has become a rapidly emerging method of lymphatic reconstruction shown to lead to lymphatic regeneration. In particular, lymphatic flaps based on the submental artery have shown good results with its favorable donor site and available nodes. The lymph nodes here are in close relation to the submandibular gland and require careful dissection around and through the gland for safe harvest...
January 5, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29308967/effects-of-kinesio-taping-on-breast-cancer-related-lymphedema-a-meta-analysis-in-clinical-trials
#8
Karina Tamy Kasawara, Jéssica Monique Rossetti Mapa, Vilma Ferreira, Marco Aurélio Nemitalla Added, Silvia Regina Shiwa, Nelson Carvas, Patricia Andrade Batista
BACKGROUND: Lymphedema is known as a secondary complication of breast cancer treatment, caused by reduction on lymphatic flow and lymph accumulation on interstitial space. The Kinesio Taping (KT) has become an alternative treatment for lymphedema volume reduction. The objective of the study was to evaluate the literature through a systematic review on KT effects on lymphedema related to breast cancer. METHODS: Search strategies were performed by the following keywords: "Kinesio Taping," "Athletic Tape," "Cancer," "Neoplasm," "Lymphedema," and "Mastectomy" with derivations and different combinations...
January 8, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29307792/further-delineation-of-the-sox18-related-hypotrichosis-lymphedema-telangiectasia-syndrome-htls
#9
Irene Valenzuela, Paula Fernández-Alvarez, Alberto Plaja, Gema Ariceta, Anna Sabaté-Rotés, Elena García-Arumí, Teresa Vendrell, Eduardo Tizzano
The transcription factor SOX18 has been shown to play a role in the development of hair, blood and lymphatic vessels. Mutations in SOX18 result in hereditary lymphedema, with the unique clinical association of hypotrichosis and telangiectasia (HLTS). Some patients present with additional disease features which may be explained by the location of SOX18 mutation. We report a patient with hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) confirmed by detection of a novel mutation in the SOX18 gene. Few cases of HTLS have been reported in the literature...
January 4, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29307097/robotic-inguinal-lymph-node-dissection-for-melanoma-a-novel-approach-to-a-complicated-problem
#10
G Alan Hyde, Nathan L Jung, Alvaro A Valle, Syamal D Bhattacharya, Christopher E Keel
BACKGROUND: Indications for superficial inguinal lymph node (ILN) dissection in melanoma include fine needle aspiration or clinically positive ILN and sentinel lymph nodes (SLN). Open inguinal lymphadenectomy may be complicated by poor wound healing, deep vein thrombosis, and lymphedema. Technical considerations and case series of a novel surgical approach, robotic inguinal lymphadenectomy, are presented. METHODS: This is a case series of four robotic ILN dissections for melanoma at a tertiary care facility...
January 6, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29306049/evaluation-of-lymphedema-in-upper-extremities-by-mr-lymphangiography-comparison-with-lymphoscintigraphy
#11
Jae Seok Bae, Roh-Eul Yoo, Seung Hong Choi, Seong Oh Park, Hak Chang, Minseok Suh, Gi Jeong Cheon
PURPOSE: To validate usefulness of magnetic resonance (MR) lymphangiography for evaluation of peripheral lymphedema in upper extremities by comparison with lymphoscintigraphy. MATERIALS AND METHODS: This prospective study had institutional review board approval and written informed consent was obtained from all patients. Initially, protocol of MR lymphangiography for upper extremity was established in seven healthy volunteers with 3.0T fat-saturated three-dimensional gradient-echo MR after gadobutrol injection...
January 3, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29304140/long-term-effects-of-manual-lymphatic-drainage-and-active-exercises-on-physical-morbidities-lymphoscintigraphy-parameters-and-lymphedema-formation-in-patients-operated-due-to-breast-cancer-a-clinical-trial
#12
Mariana Maia Freire de Oliveira, Maria Salete Costa Gurgel, Bárbara Juarez Amorim, Celso Dario Ramos, Sophie Derchain, Natachie Furlan-Santos, César Cabello Dos Santos, Luís Otávio Sarian
PURPOSE: evaluate whether manual lymphatic drainage (MLD) or active exercise (AE) is associated with shoulder range of motion (ROM), wound complication and changes in the lymphatic parameters after breast cancer (BC) surgery and whether these parameters have an association with lymphedema formation in the long run. METHODS: Clinical trial with 106 women undergoing radical BC surgery, in the Women's Integrated Healthcare Center-University of Campinas. Women were matched for staging, age and body mass index and were allocated to performed AE or MLD, 2 weekly sessions during one month after surgery...
2018: PloS One
https://www.readbyqxmd.com/read/29304095/the-effect-of-relaxation-techniques-on-edema-anxiety-and-depression-in-post-mastectomy-lymphedema-patients-undergoing-comprehensive-decongestive-therapy-a-clinical-trial
#13
Bahareh Abbasi, Navid Mirzakhany, Leila Angooti Oshnari, Ashkan Irani, Samaneh Hosseinzadeh, Seyed Mehdi Tabatabaei, Shahpar Haghighat
OBJECTIVES: Lymphedema is sometimes accompanied by high degrees of anxiety and depression. This study aimed to assess the effects of relaxation techniques on the level of edema, anxiety and depression in women undergoing Comprehensive Decongestive Therapy (CDT). DESIGN: This clinical trial compared two treatment methods in 31 women with post-mastectomy lymphedema, including 15 cases who received CDT and 16 who received RCDT (Relaxation plus CDT). The edema volume, anxiety and depression scores were compared at the first and last sessions of the first phase of the treatment and six weeks afterwards...
2018: PloS One
https://www.readbyqxmd.com/read/29303780/clinical-and-cytogenetic-features-of-516-patients-with-suspected-turner-syndrome-a-single-center-experience
#14
Annelise B Carvalho, Sofia H V Lemos-Marini, Gil Guerra-Junior, Andréa T Maciel-Guerra
BACKGROUND: Clinical suspicion of Turner syndrome (TS) may be challenging. Short stature and absent puberty are not mandatory and the dysmorphic picture is widely variable. The aim of the study was to describe a representative sample of patients with suspected TS in a single center and to verify which set of features may help discriminate those with TS. METHODS: This was a retrospective study of patients with suspected TS evaluated between 1989 and 2012 with the same clinical and cytogenetic protocols...
January 5, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29295565/prevalence-of-idiopathic-cyclic-edema-in-women-with-lower-limb-lymphedema
#15
Jose Maria Pereira de Godoy, Henrique Jose Pereira de Godoy, Lívia Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy
Cyclic edema is a clinical condition in women that leads to fluid retention in the orthostatic position. The aim of the present study was to evaluate the prevalence of idiopathic cyclic edema in women with lower limb lymphedema. The prevalence of idiopathic cyclic edema was evaluated in a retrospective study of 100 consecutive female patients submitted to leg lymphedema treatment at the Clínica Godoy. The diagnosis of lymphedema was clinical, based on patient history and a physical examination. Patients with clinical stage II lymphedema were included in the study with those in stages I and III being excluded...
December 25, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29286964/lymphaticovenous-anastomoses-for-lymphedema-complicated-by-severe-lymphorrhea-following-resection-of-soft-tissue-sarcomas-of-the-adductor-compartment-a-report-of-two-cases
#16
Hiroshi Kobayashi, Takuya Iida, Takumi Yamamoto, Masachika Ikegami, Yusuke Shinoda, Sakae Tanaka, Hirotaka Kawano
CASE: Lymphedema and lymphorrhea are major causes of wound complications after the resection of soft-tissue sarcomas in the adductor compartment of the thigh. We report 2 cases of successful treatment of lymphedema and lymphorrhea, which had been refractory to nonoperative treatment, with use of lymphaticovenous anastomosis (LVA) and intraoperative indocyanine green lymphography after the resection of a sarcoma in the adductor compartment. CONCLUSION: These 2 cases highlight that LVA can be a useful and minimally invasive alternative to myocutaneous flaps for the treatment of wound complications caused by lymphedema and lymphorrhea after surgery for soft-tissue sarcomas in the adductor compartment of the thigh...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29273307/sentinel-lymph-node-biopsy-in-endometrial-cancer-feasibility-safety-and-lymphatic-complications
#17
Barbara Geppert, Céline Lönnerfors, Michele Bollino, Jan Persson
OBJECTIVE: To compare the rate of lymphatic complications in women with endometrial cancer undergoing sentinel lymph node biopsy versus a full pelvic and infrarenal paraaortic lymphadenectomy, and to examine the overall feasibility and safety of the former. METHODS: A prospective study of 188 patients with endometrial cancer planned for robotic surgery. Indocyanine green was used to identify the sentinel lymph nodes. In low-risk patients the lymphadenectomy was restricted to removal of sentinel lymph nodes whereas in high-risk patients also a full lymphadenectomy was performed...
December 20, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29248110/quantitative-comparison-between-the-laser-scanner-three-dimensional-method-and-the-circumferential-method-for-evaluation-of-arm-volume-in-patients-with-lymphedema
#18
Nicola Cau, Manuela Galli, Veronica Cimolin, Alida Grossi, Ivan Battarin, Greta Puleo, Augusta Balzarini, Augusto Caraceni
OBJECTIVE: Several methods are used to evaluate arm volumes. The most commonly used methods are water displacement and the circumferential method (CM), but these techniques have some limitation in application in clinical settings and accuracy. Recently, the laser scanner three-dimensional (LS3D) method was successfully proposed as a valid method for volume measurements of the upper limb in healthy individuals. The aim of the study was to compare, in terms of intraobserver and interobserver reliability, the CM and LS3D method to measure the upper limb in a group of women with upper limb lymphedema...
January 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29246739/surgical-site-infection-following-lymph-node-excision-indicates-susceptibility-for-lymphedema-a-retrospective-cohort-study-of-malignant-melanoma-patients
#19
Mads Gustaf Jørgensen, Navid Mohamadpour Toyserkani, Jørn Bo Thomsen, Jens Ahm Sørensen
BACKGROUND AND OBJECTIVES: Cancer-related lymphedema is a common complication following lymph node excision. Prevention of lymphedema is essential, as treatment options are limited. Known risk factors are firmly anchored to the cancer treatment itself; however potentially preventable factors such as seroma and surgical-site infection (SSI) have yet to be asserted. METHODS: All malignant melanoma patients treated with sentinel lymph node biopsy (SNB) and/or complete lymph node dissection (CLND) in the axilla or groin between January 2008 and December 2014 were retrospectively identified...
November 28, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29242747/usefulness-of-preoperative-echography-for-detection-of-lymphatic-vessels-for-lymphaticovenous-anastomosis
#20
Hisako Hara, Makoto Mihara
Case 1: A 63-year-old woman with secondary lower limb lymphedema. As it was difficult to detect the lymphatic vessels in the right thigh in indocyanine green lymphography because of thick fat, we tried echography and observed circular structures beneath the superficial fascia. Intraoperatively, we found a dilated lymphatic vessel just as observed on echography. Case 2: A 45-year-old woman with primary lower limb lymphedema. As she was allergic to iodinated contrast medium, we could not use indocyanine green lymphography preoperatively...
2017: SAGE Open Medical Case Reports
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