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https://www.readbyqxmd.com/read/28435979/oxytocin-system-in-neuropsychiatric-disorders-old-concept-new-insights
#1
Afzal Misrani, Sidra Tabassum, Cheng Long
Oxytocin (OXT) is a neuropeptide that plays a pivotal role among species peripherally and centrally. It recently has attracted much attention for its involvement in anxiety-related behavior, stress regulation, social behavior and various neuropsychiatric disorders. OXT is one of the important mediators of emotional and social behaviors such as maternal behavior, fear extinction, social support, happiness, and trust. It is also involved in learning and memory process. The recent progresses in OXT system have put this neuropeptide as an important psychotherapeutic intervention for various psychiatric disorders such as stress, anxiety disorders, social phobia, postpartum depression, bipolar disorder, autism, and schizophrenia...
April 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/28433854/comorbidity-age-of-onset-and-suicidality-in-obsessive-compulsive-disorder-ocd-an-international-collaboration
#2
V Brakoulias, V Starcevic, A Belloch, C Brown, Y A Ferrao, L F Fontenelle, C Lochner, D Marazziti, H Matsunaga, E C Miguel, Ycj Reddy, M C do Rosario, R G Shavitt, A Shyam Sundar, D J Stein, A R Torres, K Viswasam
OBJECTIVES: To collate data from multiple obsessive-compulsive disorder (OCD) treatment centers across seven countries and five continents, and to report findings in relation to OCD comorbidity, age of onset of OCD and comorbid disorders, and suicidality, in a large clinical and ethnically diverse sample, with the aim of investigating cultural variation and the utility of the psychiatric diagnostic classification of obsessive-compulsive and related disorders. METHODS: Researchers in the field of OCD were invited to contribute summary statistics on current and lifetime psychiatric comorbidity, age of onset of OCD and comorbid disorders and suicidality in their patients with OCD...
April 12, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28432866/shared-genetic-influences-among-childhood-shyness-social-competences-and-cortical-responses-to-emotions
#3
Marco Battaglia, Giorgia Michelini, Elettra Pezzica, Anna Ogliari, Corrado Fagnani, Maria-Antonietta Stazi, Eleonora Bertoletti, Simona Scaini
Visual event-related potentials (ERPs) evoked by facial expressions are useful to map socioemotional responses among shy children and to predict transition into social phobia. We investigated the sources of covariation among childhood shyness, social competences, and ERPs to other children's happy, neutral, and angry expressions. Electrophysiological and twin analyses examined the phenotypic and etiological association among an index of childhood shyness, an index of social competences, and ERP responses to facial expressions in 200 twins (mean age=9...
April 19, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28428574/the-oral-health-of-individuals-with-dental-phobia-a-multivariate-analysis-of-the-adult-dental-health-survey-2009
#4
E Heidari, M Andiappan, A Banerjee, J T Newton
Background Adults with dental phobia have been reported to have poorer oral health and oral health-related quality of life. The aim of this study is to explore the social and demographic correlates of oral health and oral health-related quality of life (OH-QoL) of people with dental phobia compared to the non-phobic population in the United Kingdom using the data from Adult Dental Health Survey (ADHS, 2009).Method Secondary analysis of data from the ADHS, 2009. A series of logistic regression analyses was performed with outcome measures of: presence of decayed teeth; presence of missing teeth; pulp exposure ulceration fistula abscess (PUFA) score; periodontal health indices (plaque, bleeding and loss of attachments); and quality of life (oral health impact profile [OHIP14] and oral impacts on daily performance [OIDP])...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28423145/brief-behavioral-therapy-for-pediatric-anxiety-and-depression-in-primary-care-a-randomized-clinical-trial
#5
V Robin Weersing, David A Brent, Michelle S Rozenman, Araceli Gonzalez, Megan Jeffreys, John F Dickerson, Frances L Lynch, Giovanna Porta, Satish Iyengar
Importance: Anxiety and depression affect 30% of youth but are markedly undertreated compared with other mental disorders, especially in Hispanic populations. Objective: To examine whether a pediatrics-based behavioral intervention targeting anxiety and depression improves clinical outcome compared with referral to outpatient community mental health care. Design, Setting, and Participants: This 2-center randomized clinical trial with masked outcome assessment conducted between brief behavioral therapy (BBT) and assisted referral to care (ARC) studied 185 youths (aged 8...
April 19, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28421682/predicting-abstinence-from-methamphetamine-use-after-residential-rehabilitation-findings-from-the-methamphetamine-treatment-evaluation-study
#6
Rebecca McKetin, Astrid Kothe, Amanda L Baker, Nicole K Lee, Joanne Ross, Dan I Lubman
INTRODUCTION AND AIMS: We previously found that residential rehabilitation increased continuous abstinence from methamphetamine use 1 year after treatment. We examine what client and treatment characteristics predict this outcome. DESIGN AND METHODS: Participants (n = 176) were dependent on methamphetamine and entering residential rehabilitation for methamphetamine use. Simultaneous logistic regression was used to identify independent predictors of continuous abstinence from methamphetamine use at 1 year follow-up...
April 18, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28403387/skin-conductance-responses-and-neural-activations-during-fear-conditioning-and-extinction-recall-across-anxiety-disorders
#7
Marie-France Marin, Rachel G Zsido, Huijin Song, Natasha B Lasko, William D S Killgore, Scott L Rauch, Naomi M Simon, Mohammed R Milad
Importance: The fear conditioning and extinction neurocircuitry has been extensively studied in healthy and clinical populations, with a particular focus on posttraumatic stress disorder. Despite significant overlap of symptoms between posttraumatic stress disorder and anxiety disorders, the latter has received less attention. Given that dysregulated fear levels characterize anxiety disorders, examining the neural correlates of fear and extinction learning may shed light on the pathogenesis of underlying anxiety disorders...
April 12, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28396644/parent-child-diagnostic-agreement-on-anxiety-symptoms-with-a-structured-diagnostic-interview-for-mental-disorders-in-children
#8
Lukka Popp, Murielle Neuschwander, Sandra Mannstadt, Tina In-Albon, Silvia Schneider
Objective: In clinical structured diagnostic interviews, diagnoses based on parent and child reports have low to moderate agreement. The aims of the present study are (1) to examine diagnostic agreement on anxiety disorders between parents and children on the levels of current and lifetime diagnostic category and diagnoses focusing in particular on diagnostic criteria and (2) to identify parent- and child-related predictors for diagnostic agreement. Method: The sample consisted of 166 parent-child dyads interviewed with the Structured Diagnostic Interview for Mental Disorders in Children (Kinder-DIPS, Schneider et al...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28394207/the-effects-of-social-anxiety-and-online-privacy-concern-on-individual-differences-in-internet-based-interaction-anxiety-and-communication-preferences
#9
Krystelle Shaughnessy, Jessica N Rocheleau, Somayyeh Kamalou, David A Moscovitch
Social anxiety (SA) and online privacy concerns (OPCs) are conceptually distinct fears, but both may be activated by Internet-based social contexts. Whereas SA is focused on being the object of interpersonal evaluation, OPC is focused on preventing others from gaining unauthorized access to private personal information. No research to date has investigated how SA and OPCs may uniquely or interactively predict individual differences in online interaction anxiety or attitudes and preferences about online communication...
April 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28388948/investigating-the-potential-of-the-anti-epileptic-drug-imepitoin-as-a-treatment-for-co-morbid-anxiety-in-dogs-with-idiopathic-epilepsy
#10
Rowena M A Packer, Luisa De Risio, Holger A Volk
BACKGROUND: Behavioural changes associated with idiopathic epilepsy (IE) have been identified in dogs, with fear and anxiety-related problems seen in both drug-naïve dogs and dogs treated with anti-epileptic drugs (AEDs). Treating anxiety-related behaviour in dogs with IE may be challenging, as seizures are a contraindication for many conventional anxiolytic drugs. In addition, many dogs with IE are already treated with AEDs to reduce their seizure frequency, which may have negative effects if used in polytherapy...
April 7, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28380173/academic-performance-of-students-who-underwent-psychiatric-treatment-at-the-students-mental-health-service-of-a-brazilian-university
#11
Cláudia Ribeiro Franulovic Campos, Maria Lilian Coelho Oliveira, Tânia Maron Vichi Freire de Mello, Clarissa de Rosalmeida Dantas
CONTEXT AND OBJECTIVE: University students are generally at the typical age of onset of mental disorders that may affect their academic performance. We aimed to characterize the university students attended by psychiatrists at the students' mental health service (SAPPE) and to compare their academic performance with that of non-patient students. DESIGN AND SETTING: Cross-sectional study based on review of medical files and survey of academic data at a Brazilian public university...
January 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28371642/the-impact-of-social-threat-cues-on-a-card-sorting-task-with-attentional-shifting-demands
#12
Jan Mohlman, Alyssa DeVito
BACKGROUND AND OBJECTIVES: The current study investigated social anxiety and attentional control using two versions of a task designed to tap intentional shifting of attention and set switching: the standard Wisconsin Card Sorting Test (WCST; Heaton, 1981) and a modified version that included emotionally salient pictorial stimuli, the Emotional Faces Card Sorting Test (EFCST). A Group (lower-, higher-SPS) by Condition (WCST, EFCST) by Sorting Rule (color, form, number) interaction was expected in which the higher-SPS EFCST group would have worse overall performance and make more perseverative errors than the other groups...
March 7, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28369890/impact-of-childhood-trauma-on-course-of-panic-disorder-contribution-of-clinical-and-personality-characteristics
#13
Maud De Venter, Filip Van Den Eede, Thomas Pattyn, Kristien Wouters, Dick J Veltman, Brenda W J H Penninx, Bernard G Sabbe
OBJECTIVE: To investigate the impact of childhood trauma on the clinical course of panic disorder and possible contributing factors. METHOD: Longitudinal data of 539 participants with a current panic disorder were collected from the Netherlands Study of Depression and Anxiety (NESDA). Childhood trauma was assessed with a structured interview and clinical course after 2 years with a DSM-IV-based diagnostic interview and the Life Chart Interview. RESULTS: At baseline, 54...
March 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28364210/being-poorer-than-the-rest-of-the-neighborhood-relative-deprivation-and-problem-behavior-of-youth
#14
Jaap Nieuwenhuis, Maarten van Ham, Rongqin Yu, Susan Branje, Wim Meeus, Pieter Hooimeijer
According to the neighborhood effects hypothesis, there is a negative relation between neighborhood wealth and youth's problem behavior. It is often assumed that there are more problems in deprived neighborhoods, but there are also reports of higher rates of behavioral problems in more affluent neighborhoods. Much of this literature does not take into account relative wealth. Our central question was whether the economic position of adolescents' families, relative to the neighborhood in which they lived, was related to adolescents' internalizing and externalizing problem behavior...
March 31, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28360934/sleep-disturbances-and-mental-strain-in-university-students-results-from-an-online-survey-in-luxembourg-and-germany
#15
Angelika A Schlarb, Merle Claßen, Julia Grünwald, Claus Vögele
OBJECTIVES: This study examined the prevalence of sleep disturbances and mental strain in students from two European countries, Luxembourg and Germany. METHODS: A total of 2831 students took part in an online survey, with 2777 students from Germany and 184 students from Luxembourg. Sleep disturbances were assessed with the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale, and aspects of mental strain using the Patient Health Questionnaire, the Social-Interactive-Anxiety Scale, the self-efficacy questionnaire and the test anxiety questionnaire...
2017: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/28348539/autonomic-reactivity-to-arousing-stimuli-with-social-and-non-social-relevance-in-alexithymia
#16
Eduardo S Martínez-Velázquez, Jacques Honoré, Lucas de Zorzi, Julieta Ramos-Loyo, Henrique Sequeira
Emotional difficulties in alexithymia and their social consequences have been linked to alterations in autonomic nervous system. However, most of previous studies did not take into account the distinction between the affective and the cognitive dimensions of the alexithymia, leading to inconsistent results. Aim: In this study, we compared the effects of both dimensions of alexithymia on the autonomic arousal to emotional and social visual stimulations. Methods: Skin conductance responses (SCRs) to items of the International Affective Pictures System characterized by emotional (unpleasant, neutral, and pleasant), social (with humans) or non-social (without humans) content were recorded in non-alexithymic (NA), affective (AA) and cognitive alexithymic (CA) participants, selected on the basis of the Toronto Alexithymia Scale and the Bermond-Vorst Alexithymia Questionnaire...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28326752/minimal-role-of-comorbid-personality-disorder-on-the-quality-of-life-in-patients-with-anxiety-spectrum-disorders
#17
Dana Kamaradova, Klara Latalova, Jan Prasko, Ales Grambal, Zuzana Sigmundova, Petra Kasalova, Snezana Cakirpaloglu
OBJECTIVES: There is no consensus on the definition of Quality of life (QoL). It is considered to be comprised of both psychological and somatical well-being. A variety of tools has been developed to measure subjective and objective (QoL). A number of factors, including demographical and medical may have an impact on QoL. The aim of our study was to compare the QoL in selected anxiety disorders and evaluate the influence of comorbid personality disorder. METHOD: We evaluated data from 278 patients suffering from social phobia, panic disorder and/or agoraphobia, adjustment disorder, generalized anxiety disorder and obsessive-compulsive disorder...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28300935/specific-and-social-fears-in-children-and-adolescents-separating-normative-fears-from-problem-indicators-and-phobias
#18
Paola P Laporte, Pedro M Pan, Mauricio S Hoffmann, Lauren S Wakschlag, Luis A Rohde, Euripedes C Miguel, Daniel S Pine, Gisele G Manfro, Giovanni A Salum
Objective: To distinguish normative fears from problematic fears and phobias. Methods: We investigated 2,512 children and adolescents from a large community school-based study, the High Risk Study for Psychiatric Disorders. Parent reports of 18 fears and psychiatric diagnosis were investigated. We used two analytical approaches: confirmatory factor analysis (CFA)/item response theory (IRT) and nonparametric receiver operating characteristic (ROC) curve. Results: According to IRT and ROC analyses, social fears are more likely to indicate problems and phobias than specific fears...
March 9, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28299314/high-magnitude-of-social-anxiety-disorder-in-school-adolescents
#19
Kindie Mekuria, Haregwoin Mulat, Habtamu Derajew, Tesfa Mekonen, Wubalem Fekadu, Amsalu Belete, Solomon Yimer, Getasew Legas, Melak Menberu, Asmamaw Getnet, Simegnew Kibret
Introduction. Social phobia is the most prevalent and chronic type of anxiety disorder worldwide and it affects occupational, educational, and social affairs of the individual. Social phobia is also known for its association with depression and substance use disorder. Objective. The aim of this study was to assess the prevalence and associated factors of social phobia among high school students in Ethiopia. Methods. Cross-sectional study was conducted among 386 randomly selected students. Data were collected using pretested and self-administered questionnaire...
2017: Psychiatry Journal
https://www.readbyqxmd.com/read/28284107/clinical-characteristics-and-treatment-outcomes-of-patients-with-major-depressive-disorder-and-comorbid-anxiety-disorders-results-from-a-european-multicenter-study
#20
Markus Dold, Lucie Bartova, Daniel Souery, Julien Mendlewicz, Alessandro Serretti, Stefano Porcelli, Joseph Zohar, Stuart Montgomery, Siegfried Kasper
This naturalistic European multicenter study aimed to elucidate the association between major depressive disorder (MDD) and comorbid anxiety disorders. Demographic and clinical information of 1346 MDD patients were compared between those with and without concurrent anxiety disorders. The association between explanatory variables and the presence of comorbid anxiety disorders was examined using binary logistic regression analyses. 286 (21.2%) of the participants exhibited comorbid anxiety disorders, 10.8% generalized anxiety disorder (GAD), 8...
February 27, 2017: Journal of Psychiatric Research
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