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https://www.readbyqxmd.com/read/29767222/mortality-in-asthma-chronic-obstructive-pulmonary-disease-overlap-in-the-united-states
#1
Suchit Kumbhare, Charlie Strange
OBJECTIVES: Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is recognized increasingly as a distinct clinical entity and is associated with higher comorbidities compared with patients with asthma and COPD alone. Little is known about the leading causes of death related to ACO in the US general population, however. Our aim was to define the causes of mortality among patients with ACO compared with asthma and COPD in the US population. METHODS: We examined questions using the National Health and Nutrition Examination Survey III database linked to the National Death Index...
May 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29755730/having-concomitant-asthma-phenotypes-is-common-and-independently-relates-to-poor-lung-function-in-nhanes-2007-2012
#2
Rita Amaral, João A Fonseca, Tiago Jacinto, Ana M Pereira, Andrei Malinovschi, Christer Janson, Kjell Alving
Background: Evidence for distinct asthma phenotypes and their overlap is becoming increasingly relevant to identify personalized and targeted therapeutic strategies. In this study, we aimed to describe the overlap of five commonly reported asthma phenotypes in US adults with current asthma and assess its association with asthma outcomes. Methods: Data from the National Health and Nutrition Examination Surveys (NHANES) 2007-2012 were used (n = 30,442). Adults with current asthma were selected...
2018: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29730665/associations-between-dietary-patterns-and-post-bronchodilation-lung-function-in-the-sapaldia-cohort
#3
Nina Steinemann, Leticia Grize, Marco Pons, Thomas Rothe, Daiana Stolz, Alexander Turk, Christian Schindler, Christine Brombach, Nicole Probst-Hensch
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is not restricted to smokers. Dietary habits may contribute to the disease occurrence. Epidemiological studies point to a protective effect of fruit and vegetable intake against COPD. OBJECTIVE: To investigate the associations between dietary patterns and parameters of lung function related to COPD in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). METHODS: Data were included from the second follow-up assessment of the SAPALDIA cohort in 2010-2011 using a food frequency questionnaire...
May 4, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29716592/pollution-and-respiratory-disease-can-diet-or-supplements-help-a-review
#4
REVIEW
T Whyand, J R Hurst, M Beckles, M E Caplin
Pollution is known to cause and exacerbate a number of chronic respiratory diseases. The World Health Organisation has placed air pollution as the world's largest environmental health risk factor. There has been recent publicity about the role for diet and anti-oxidants in mitigating the effects of pollution, and this review assesses the evidence for alterations in diet, including vitamin supplementation in abrogating the effects of pollution on asthma and other chronic respiratory diseases. We found evidence to suggest that carotenoids, vitamin D and vitamin E help protect against pollution damage which can trigger asthma, COPD and lung cancer initiation...
May 2, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29713158/heterogeneity-of-asthma-and-copd-overlap
#5
Min-Hye Kim, Chin Kook Rhee, Kyungjoo Kim, Sang Hyun Kim, Jung Yeon Lee, Yee Hyung Kim, Kwang Ha Yoo, Young-Joo Cho, Ki-Suck Jung, Jin Hwa Lee
Background: Asthma and COPD are heterogeneous diseases. Patients with both disease features (asthma-COPD overlap [ACO]) are common. However, clinical characteristics and socio-economic burden of ACO are still controversial. The aim of this study was to identify the heterogeneity of ACO and to find out the subtypes with clinical impact among ACO subtypes. Methods: In the Korean National Health and Nutrition Examination Survey (KNHANES) conducted between 2007 and 2012, subjects who were ≥40 years and had prebronchodilator FEV1 /FVC <0...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29707563/copd-time-to-improve-its-taxonomy
#6
Bartolomé R Celli, Alvar Agustí
Due to well-conducted epidemiological studies and advances in genetics, molecular biology, translational research, the advent of computed tomography of the lungs and bioinformatics, the diagnosis of chronic obstructive pulmonary disease (COPD) as a single entity caused by susceptibility to cigarette smoke is no longer tenable. Furthermore, the once-accepted concept that COPD results from a rapid and progressive loss of lung function over time is not true for a sizeable proportion of adults with the disease...
January 2018: ERJ Open Research
https://www.readbyqxmd.com/read/29683370/nutritional-supplement-bao-khi-khang-as-an-adjuvant-therapy-in-acute-exacerbations-of-chronic-obstructive-pulmonary-disease
#7
Ba X Hoang, Bo Han, Hoang X Nguyen, Khanh T Dang
To investigate the effectiveness of nutritional supplement Bao Khi Khang as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease (COPD) compared to conventional therapy alone. This was a prospective, randomized, open-label controlled trial in 60 patients presenting with acute exacerbation of COPD. Patients were randomized into two groups, the control and the experimental groups. The control group was treated with the standard therapeutic protocol (Antimicrobial+Corticosteroids+Bronchodilator+Mucolytic drugs)...
April 23, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29629039/relationships-of-serum-iron-parameters-and-hemoglobin-with-forced-expiratory-volume-in-1-second-in-patients-with-chronic-obstructive-pulmonary-disease
#8
Mi-Hye Kim, Yong-Hwan Kim, Duk-Chul Lee
Background: Although chronic obstructive pulmonary disease is a known cause of secondary polycythemia with elevated erythropoietic demands in response to hypoxemia, anemia is relatively common in patients with chronic obstructive pulmonary disease and is related to increased mortality. However, little is currently known about the relationship between various iron parameters and disease severity in chronic obstructive pulmonary disease patients. Methods: Data from the fifth Korean National Health and Nutrition Examination Survey, a population-based epidemiologic survey conducted in 2010-2012, were used...
March 2018: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29627816/effects-of-dietary-antioxidant-vitamins-on-lung-functions-according-to-gender-and-smoking-status-in-korea-a-population-based-cross-sectional-study
#9
Ji Young Hong, Chang Youl Lee, Myung Goo Lee, Young Sam Kim
OBJECTIVE: Cigarette smoke-induced oxidative stress plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Dietary antioxidants are thought to prevent smoke-induced oxidative damage. The aim of this study was to investigate associations between lung function and the consumption of antioxidant vitamins in Korean adults. METHODS: In total, 21 148 participants from the Korean National Health and Nutrition Examination Survey (2007-2014) were divided into four groups based on smoking history and gender...
April 7, 2018: BMJ Open
https://www.readbyqxmd.com/read/29559774/comparison-of-the-fixed-ratio-and-the-z-score-of-fev-1-fvc-in-the-elderly-population-a-long-term-mortality-analysis-from-the-third-national-health-and-nutritional-examination-survey
#10
Dong Kyu Oh, Seunghee Baek, Sei Won Lee, Jae Seung Lee, Sang-Do Lee, Yeon-Mok Oh
Background and objective: Despite the ongoing intense debate on the definition of airflow limitation by spirometry in the elderly population, there have only been few studies comparing the fixed ratio and the Z -score of forced expiratory volume in 1 second (FEV1 )/forced vital capacity (FVC) in terms of long-term mortalities. In this study, we aimed to identify the proper method for accurately defining the airflow limitation in terms of long-term mortality prediction in the elderly population...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29554438/skeletal-muscle-dysfunction-in-chronic-obstructive-pulmonary-disease-copd-what-we-know-and-can-do-for-our-patients
#11
Ariel Jaitovich, Esther Barreiro
Skeletal muscle dysfunction occurs in COPD patients and affects both ventilatory and non-ventilatory muscle groups. It represents a very important comorbidity that associates with poor quality of life and reduced survival, and results from a complex combination of functional, metabolic and anatomical alterations leading to suboptimal muscle work. Muscle atrophy, altered fiber type and metabolism and chest wall remodeling -in the case of the respiratory muscles- are relevant etiologic contributors to this process...
March 19, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29520135/co-existence-of-copd-and-bronchiectasis-a-risk-factor-for-a-high-ratio-of-main-pulmonary-artery-to-aorta-diameter-pa-a-from-computed-tomography-in-copd-patients
#12
Shuang Dou, Chunyan Zheng, Xiuli Ji, Wei Wang, Mengshuang Xie, Liwei Cui, Wei Xiao
Background: Pulmonary vascular disease, especially pulmonary hypertension, is an important complication of COPD. Bronchiectasis is considered not only a comorbidity of COPD, but also a risk factor for vascular diseases. The main pulmonary artery to aorta diameter ratio (PA:A ratio) has been found to be a reliable indicator of pulmonary vascular disease. It is hypothesized that the co-existence of COPD and bronchiectasis may be associated with relative pulmonary artery enlargement (PA:A ratio >1)...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29520134/obstructive-sleep-apnea-copd-the-overlap-syndrome-and-mortality-results-from-the-2005-2008-national-health-and-nutrition-examination-survey
#13
Wei Du, Jun Liu, Jianlong Zhou, Dan Ye, Yan OuYang, Qingnan Deng
Objective: The aim of this study was to investigate the role of obstructive sleep apnea (OSA) on all-cause mortality in patients with COPD. Methods: Data for this cross-sectional study were obtained from the National Health and Nutrition Examination Survey (NHANES) data (year 2005-2008). Eligible subjects were ≥20 years who had no COPD or OSA (n=9,237), had only OSA (n=366), had only COPD (n=695), and had OSA/COPD overlap syndrome (n=90). Univariate and multivariate analyses were used to evaluate factors associated with overall mortality...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29508694/association-of-energy-and-protein-intakes-with-length-of-stay-readmission-and-mortality-in-hospitalised-patients-with-chronic-obstructive-pulmonary-disease
#14
Arora R Ingadottir, Anne M Beck, Christine Baldwin, C Elizabeth Weekes, Olof G Geirsdottir, Alfons Ramel, Thorarinn Gislason, Ingibjorg Gunnarsdottir
Low energy and protein intakes have been associated with an increased risk of malnutrition in outpatients with chronic obstructive pulmonary disease (COPD). We aimed to assess the energy and protein intakes of hospitalised COPD patients according to nutritional risk status and requirements, and the relative contribution from meals, snacks, drinks and oral nutritional supplements (ONS), and to examine whether either energy or protein intake predicts outcomes. Subjects were COPD patients (n 99) admitted to Landspitali University Hospital in 1 year (March 2015-March 2016)...
March 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29494211/disease-management-plus-recommended-care-versus-recommended-care-alone-for-ambulatory-copd-patients
#15
Ofra Kalter-Leibovici, Michal Benderly, Laurence S Freedman, Galit Kaufman, Tchiya Molcho Falkenberg Luft, Havi Murad, Liraz Olmer, Meri Gluch, David Segev, Avi Gilad, Said Elkrinawi, Tali Cukierman-Yaffe, Baruch Chen, Orit Jacobson, Calanit Key, Mordechai Shani, Gershon Fink
RATIONALE: The efficacy of disease management programs in the treatment of patients with chronic obstructive pulmonary disease (COPD) remains uncertain. OBJECTIVE: To study the effect of disease management (DM) added to recommended care (RC) in ambulatory COPD patients. MEASUREMENTS AND MAIN RESULTS: In this trial, 1,202 COPD patients (age >40 years), with moderate to very severe airflow limitation were randomly assigned either to DM plus RC (study intervention) or to RC alone (control intervention)...
March 1, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29413494/malnutrition-and-sarcopenia-assessment-in-patients-with-chronic-obstructive-pulmonary-disease-according-to-international-diagnostic-criteria-and-evaluation-of-raw-bia-variables
#16
Francesca de Blasio, Ada Di Gregorio, Francesco de Blasio, Andrea Bianco, Barbara Bellofiore, Luca Scalfi
BACKGROUND: Various criteria have been used so far for the diagnosis of malnutrition or sarcopenia in patients suffering from chronic obstructive pulmonary disease (COPD). OBJECTIVE: To determine the prevalence of malnutrition and sarcopenia in COPD, as defined by international diagnostic criteria, and determine their relationships with raw BIA variables. METHODS: Two-hundred and sixty-three COPD patients (185 males and 78 females) underwent both clinical examination and respiratory, anthropometric, bioelectrical impedance analysis (BIA raw variables: phase angle and impedance ratio), handgrip strength (HGS), 4 m gait speed and biochemical measurements...
January 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29402358/-effect-of-early-mobilization-on-diaphragmatic-function-in-patients-with-mechanical-ventilation-a-prospective-randomized-controlled-study
#17
Shengqiang Yang, Jinggang Liu, Wenbao Yang, Jiyin Yuan, Suqiu Meng, Maoling Liang, Qibiao Shi
OBJECTIVE: To investigate the effect of early mobilization on diaphragmatic function in patients with mechanical ventilation (MV). METHODS: Sixty chronic obstructive pulmonary disease with acute exacerbation (AECOPD) patients with respiratory failure (RF) and underwent MV admitted to intensive care unit (ICU) of Huxi Affiliated Hospital of Jining Medical College from January 2016 to January 2017 were enrolled. The patients were divided into treatment group (n = 30) and control group (n = 30) by randomly number table method...
February 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29378037/consuming-green-tea-at-least-twice-each-day-is-associated-with-reduced-odds-of-chronic-obstructive-lung-disease-in-middle-aged-and-older-korean-adults
#18
Chang-Mo Oh, In-Hwan Oh, Bong-Keun Choe, Tai-Young Yoon, Joong-Myung Choi, Jihyen Hwang
Background: The frequent consumption of green tea has been shown to have antioxidant and anti-inflammatory effects and to reduce the risk of lung cancer and type 2 diabetes. However, few studies have investigated the relation between green tea consumption and the risk of chronic obstructive lung disease (COPD). Objective: This study aimed to examine the association between green tea intake and COPD with the use of a nationwide representative database. Methods: This study was designed as a cross-sectional survey with the use of data from the Korean National Health and Nutritional Examination Survey collected between 2008 and 2015...
January 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29259964/prevalence-of-osteoporosis-in-korean-patients-with-chronic-obstructive-pulmonary-disease-and-their-health-related-quality-of-life-according-to-the-korea-national-health-and-nutrition-examination-survey-2008-2011
#19
Sang Hee Lee, Hye-Young Kwon
Background: In this study, we evaluated the prevalence of osteoporosis, risk factors associated with osteoporosis, and health-related quality of life (HRQOL) in clinically stable chronic obstructive pulmonary disease (COPD) patients. Methods: A total of 1,081 COPD patients were recruited from the Korea National Health and Nutrition Examination Survey (KNHANES) from July 2008 to May 2011. Bone mineral densities at the lumbar spine, femoral neck, and total proximal femur were measured using dual energy X-ray absorptiometry...
November 2017: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29228436/the-effect-of-ventilator-mask-atomization-inhalation-of-ipratropium-bromide-and-budesonide-suspension-liquid-in-the-treatment-of-copd-in-acute-exacerbation-period-on-circulating-levels-of-inflammation-and-prognosis
#20
D-H Jiang, X Wang, L-S Liu, D-D Ji, N Zhang
OBJECTIVE: We investigated the effects of ventilator mask atomization inhalation of ipratropium bromide and budesonide suspension liquid in the treatment of acute exacerbation COPD (AECOPD) on circulating levels of inflammatory factors and prognosis. PATIENTS AND METHODS: A total of 86 cases of patients on ventilator support were randomly divided into control group and observation group with 43 cases each. The control group was administered routine treatment including basic disease treatment, anti-infection, maintenance of a stable internal environment, nutritional support, oxygen inhalation and so on...
November 2017: European Review for Medical and Pharmacological Sciences
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