keyword
https://read.qxmd.com/read/38697299/diabetes-and-risk-of-acute-coronary-syndrome-in-callers-with-chest-discomfort-cross-sectional-study-in-out-of-hours-primary-care
#1
JOURNAL ARTICLE
Michelle Spek, Daphne C A Erkelens, Coralie van Het Goor-van Wezep, Maarten van Smeden, Hester M Den Ruijter, Loes T C M Wouters, Roderick P Venekamp, Frans H Rutten, Dorien L Zwart
AIMS: We investigated the differences in prevalence of acute coronary syndrome (ACS) by presence versus absence of diabetes in males and females with chest discomfort who called out-of-hours primary care (OHS-PC). METHODS: A cross sectional study performed in the Netherlands. Patients who called the OHS-PC in the Utrecht region, the Netherlands between 2014 and 2017 with acute chest discomfort were included. We compared those with diabetes with those without diabetes...
April 30, 2024: Diabetes Research and Clinical Practice
https://read.qxmd.com/read/38544823/exploring-the-role-of-non-synonymous-and-deleterious-variants-identified-in-colorectal-cancer-a-multi-dimensional-computational-scrutiny-of-exomes
#2
JOURNAL ARTICLE
Chandrashekar Karunakaran, Vidya Niranjan, Anagha S Setlur, Dhanya Pradeep, Jitendra Kumar
INTRODUCTION: Colorectal cancers are the world's third most commonly diagnosed type of cancer. Currently, there are several diagnostic and treatment options to combat it. However, a delay in detection of the disease is life-threatening. Additionally, a thorough analysis of the exomes of cancers reveals potential variation data that can be used for early disease prognosis. METHODS: By utilizing a comprehensive computational investigation, the present study aimed to reveal mutations that could potentially predispose to colorectal cancer...
February 23, 2024: Current Genomics
https://read.qxmd.com/read/38470216/impact-of-clonal-hematopoiesis-of-indeterminate-potential-on-hepatocellular-carcinoma-in-individuals-with-steatotic-liver-disease
#3
JOURNAL ARTICLE
Alfredo Marchetti, Serena Pelusi, Alessio Marella, Francesco Malvestiti, Antony Ricchiuti, Luisa Ronzoni, Marta Lionetti, Vittoria Moretti, Elisabetta Bugianesi, Luca Miele, Umberto Vespasiani-Gentilucci, Paola Dongiovanni, Alessandro Federico, Giorgio Soardo, Roberta D'Ambrosio, Misti V McCain, Helen L Reeves, Vincenzo La Mura, Daniele Prati, Niccolò Bolli, Luca Valenti
BACKGROUND AIMS: Metabolic dysfunction associated steatotic liver disease (MASLD) is a global epidemic and is the most rapidly rising cause of hepatocellular carcinoma (HCC). Clonal hematopoiesis of indeterminate potential (CHIP) contributes to neoplastic and cardiometabolic disorders and is considered a harbinger of tissue inflammation. CHIP was recently associated with increased risk of liver disease. The aim of this study was to examine whether CHIP is associated with HCC development in patients with SLD...
March 11, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38381768/understanding-patient-and-family-utilisation-of-community-based-palliative-care-services-out-of-hours-additional-analysis-of-systematic-review-evidence-using-narrative-synthesis
#4
JOURNAL ARTICLE
Joanna Goodrich, Caleb Watson, Inez Gaczkowska, Richard Harding, Catherine Evans, Alice Firth, Fliss E M Murtagh
BACKGROUND: Community-based out-of-hours services are an integral component of end-of-life care. However, there is little understanding of how patients and families utilise these services. This additional analysis of a systematic review aims to understand and identify patterns of out-of-hours service use and produce recommendations for future service design. METHOD: Data on service use was extracted and secondary analysis undertaken, from a systematic review of models of community out-of-hours services...
2024: PloS One
https://read.qxmd.com/read/38328469/managing-high-frequency-of-ambulance-calls-in-hospitals-a-systematic-review
#5
REVIEW
Abdullah Alruwaili, Ahmed Alanazy, Turki M Alanazi, Nowaf Alobaidi, Ahmad Saleh Almamary, Bandar M Faqihi, Fahad H Al Enazi, Rayan Siraj, Yasir Almukhlifi, Ziyad F Al Nufaiei, Maher Alsulami
BACKGROUND: This study addresses the critical issue of high-volume emergency calls in hospitals, focusing on the strain caused by frequent caller patients on ambulance services. The aim was to synthesize various management methods for handling high-frequency hospital calls. METHODS: The systematic review was conducted following the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines and guided by the Cochrane Handbook for systematic reviews...
2024: Risk Management and Healthcare Policy
https://read.qxmd.com/read/38246793/-i-wasn-t-expecting-that-question-responses-to-requests-for-abortion-referral-at-college-student-health-centers
#6
JOURNAL ARTICLE
Priyanka Anand, Licia Bravo, Sarah Gutman, Arden McAllister, Shimrit Keddem, Sarita Sonalkar
BACKGROUND: Women 18-24 years of age have the highest proportion of unintended pregnancies of any age group, and thus represent a significant population in need of abortion services. Prior research indicated that only half of college student health centers provide appropriate abortion referrals. Our objective was to better understand the referral experience and barriers to abortion referral at college student health centers. PROCEDURES: We conducted a "secret caller" study at all 4-year colleges in Pennsylvania between June 2017 and April 2018, using a structured script requesting abortion referral...
January 20, 2024: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://read.qxmd.com/read/38160901/barriers-to-cpr-initiation-and-continuation-during-the-emergency-call-relating-to-out-of-hospital-cardiac-arrest-a-descriptive-cohort-study
#7
JOURNAL ARTICLE
Emogene S Aldridge, Nirukshi Perera, Stephen Ball, Tanya Birnie, Alani Morgan, Austin Whiteside, Janet Bray, Judith Finn
AIM: To describe the barriers to cardiopulmonary resuscitation (CPR) initiation and continuation in emergency calls for out-of-hospital cardiac arrest (OHCA). METHODS: We analysed 295 consecutive emergency calls relating to OHCA over a four-month period (1 January - 30 April 2021). Calls included were paramedic-confirmed, non-traumatic, non-EMS-witnessed OHCA, where the caller was with the patient. Calls were listened to in full and coded in terms of barriers to CPR initiation and continuation, and patient and caller characteristics...
December 29, 2023: Resuscitation
https://read.qxmd.com/read/37886718/hydrofluoric-acid-ingestions-retrospective-evaluations-from-cases-reported-to-the-national-poison-data-system-2007-2017
#8
JOURNAL ARTICLE
Zachary Illg, Joseph Carpenter, Tim P Moran, Emily Kiernan, Brian Patrick Murray
BACKGROUND: Hydrofluoric acid (HF) is associated with systemic toxicity, particularly with high-concentration formulations. However, most existing data describe dermal exposures; there is a paucity of data related to outcomes after ingestions. OBJECTIVE: To determine the morbidity and mortality associated with HF ingestions as reported to the National Poison Data System (NPDS). A secondary objective is to assess for clinical criteria that are associated with serious outcomes after HF ingestion...
October 2023: Journal of the American College of Emergency Physicians open
https://read.qxmd.com/read/37852810/older-adult-frequent-9-1-1-callers-for-emergency-medical-services-in-a-large-metropolitan-city-individual-and-system-level-considerations
#9
JOURNAL ARTICLE
Beatrice Martínez, María P Aranda, Stephen Sanko, Iris Aguilar, William A Vega
BACKGROUND: High utilizers of 9-1-1 place a substantial burden on emergency medical services (EMS). Results of a retrospective review of records data of the City of Los Angeles Fire Department (LAFD) showed a significant increase in older adult high utilizers of 9-1-1. OBJECTIVE: The objective of this study was to explore individual- and system-level factors implicated in EMS use among older adults, and to provide system recommendations to mitigate overuse. METHODS: A phenomenological study was conducted, drawing from LAFD EMS records between 2012 and 2016 to identify and contact high-utilizing patients older than 50 years, their family, agency representatives, and LAFD personnel...
December 2023: Journal of Emergency Medicine
https://read.qxmd.com/read/37835427/reproducible-bioinformatics-analysis-workflows-for-detecting-igh-gene-fusions-in-b-cell-acute-lymphoblastic-leukaemia-patients
#10
JOURNAL ARTICLE
Ashlee J Thomson, Jacqueline A Rehn, Susan L Heatley, Laura N Eadie, Elyse C Page, Caitlin Schutz, Barbara J McClure, Rosemary Sutton, Luciano Dalla-Pozza, Andrew S Moore, Matthew Greenwood, Rishi S Kotecha, Chun Y Fong, Agnes S M Yong, David T Yeung, James Breen, Deborah L White
B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by diverse genomic alterations, the most frequent being gene fusions detected via transcriptomic analysis (mRNA-seq). Due to its hypervariable nature, gene fusions involving the Immunoglobulin Heavy Chain ( IGH ) locus can be difficult to detect with standard gene fusion calling algorithms and significant computational resources and analysis times are required. We aimed to optimize a gene fusion calling workflow to achieve best-case sensitivity for IGH gene fusion detection...
September 26, 2023: Cancers
https://read.qxmd.com/read/37824241/health-related-outcomes-among-veterans-identified-as-being-at-increased-risk-during-a-crisis-line-contact
#11
JOURNAL ARTICLE
Kelly A Stearns-Yoder, Molly E Penzenik, Jeri E Forster, Chelsea M Cogan, MaryGrace Lauver, Lisa A Brenner
Research has focused on developing ways to prevent death by suicide, such as 24-hr crisis lines. The purpose of the study was to examine health-related outcomes among individuals using Veterans Crisis Line services who were evaluated to be at increased risk. Among those with identifying information, records were linked with electronic medical record and death data. 36,133 contacts were coded, and 9,010 Veteran contacts were linked to external data. For 3,331 contacts (37.0%), responders initiated a facility transport plan (FTP; self-transport)...
October 12, 2023: Psychological Services
https://read.qxmd.com/read/37821905/challenges-in-recruiting-frequent-users-of-ambulance-services-for-a-community-paramedic-home-visit-program
#12
JOURNAL ARTICLE
Mikayla Plishka, Ricardo Angeles, Melissa Pirrie, Francine Marzanek, Gina Agarwal
BACKGROUND: The Community Paramedicine at Home (CP@home) program is a health promotion program where community paramedics conduct risk assessments with frequent 9-1-1 callers in their homes, with a goal of reducing the frequency of 9-1-1 calls in this vulnerable population. The effectiveness of the CP@home program was investigated through a community-based RCT conducted in four regions in Ontario, Canada. The purpose of this current recruitment study is to examine the challenges met when recruiting for a community randomized control trial on high frequency 9-1-1 callers...
October 12, 2023: BMC Health Services Research
https://read.qxmd.com/read/37620118/accurate-and-fast-graph-based-pangenome-annotation-and-clustering-with-ggcaller
#13
JOURNAL ARTICLE
Samuel T Horsfield, Gerry Tonkin-Hill, Nicholas J Croucher, John A Lees
Bacterial genomes differ in both gene content and sequence mutations, which underlies extensive phenotypic diversity, including variation in susceptibility to antimicrobials or vaccine-induced immunity. To identify and quantify important variants, all genes within a population must be predicted, functionally annotated and clustered, representing the pangenome. Despite the volume of genome data available, gene prediction and annotation are currently conducted in isolation on individual genomes, which is computationally inefficient and frequently inconsistent across genomes...
August 24, 2023: Genome Research
https://read.qxmd.com/read/37583510/comparison-of-outcomes-of-out-of-hospital-cardiac-arrest-patients-emergency-calls-placed-from-mobile-phones-vs-landline-phones
#14
JOURNAL ARTICLE
Takeshi Nishimura, Masafumi Suga, Takashi Hongo, Tetsuya Yumoto, Atsunori Nakao, Satoshi Ishihara, Hiromichi Naito
BACKGROUND: Until recently, calls to the emergency medical service (EMS) from landline phones, which display the caller's exact location at the dispatch center, had been common. Since the use of mobile phones has become widespread, many emergency calls are now made from mobile phones. Differences in outcomes of out-of-hospital cardiac arrest (OHCA) patients for whom EMS was called from mobile versus landline phones has not yet been fully elucidated. METHODS: We performed a retrospective, population-based analysis in Kobe, Japan to examine whether EMS calls from mobiles improved the prognosis of OHCA patients over EMS calls placed from landlines...
September 2023: Resuscitation plus
https://read.qxmd.com/read/37578195/experiences-and-views-of-people-who-frequently-call-emergency-ambulance-services-a-qualitative-study-of-uk-service-users
#15
JOURNAL ARTICLE
Bridie A Evans, Ashra Khanom, Adrian Edwards, Bethan Edwards, Angela Farr, Theresa Foster, Rachael Fothergill, Penny Gripper, Imogen Gunson, Alison Porter, Nigel Rees, Jason Scott, Helen Snooks, Alan Watkins
INTRODUCTION: People who call emergency ambulances frequently are often vulnerable because of health and social circumstances, have unresolved problems or cannot access appropriate care. They have higher mortality rates. Case management by interdisciplinary teams can help reduce demand for emergency services and is available in some UK regions. We report results of interviews with people who use emergency ambulance services frequently to understand their experiences of calling and receiving treatment...
August 14, 2023: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://read.qxmd.com/read/37516935/establishment-of-the-first-australian-public-and-health-professional-palliative-care-advice-service-exploring-caller-needs-and-gaps-in-care
#16
JOURNAL ARTICLE
David J T Marco, Esther McMillan-Drendel, Jennifer A M Philip, Theresa Williamson, Brian Le
This study explores and describes the state-wide needs of the first 1000 calls to the newly established Victorian Palliative Care Advice Service (PCAS). A retrospective analysis investigated calls from the Victorian general public (n = 618 calls) and healthcare professionals (n = 382 calls) to PCAS between 26 May 2020 and 24 October 2022. Caller demographics, disease type, reason for call, and perceived utility of service were described. Most calls were from members of the public (62%) and related to malignant conditions (41%)...
July 30, 2023: Australian Health Review: a Publication of the Australian Hospital Association
https://read.qxmd.com/read/37325074/prospective-mixed-methods-study-evaluating-the-potential-of-a-voicebot-covbot-to-relieve-german-health-authorities-during-the-covid-19-infodemic
#17
JOURNAL ARTICLE
Vanessa Voelskow, Claudia Meßner, Tobias Kurth, Amelie Busam, Toivo Glatz, Natalie Ebert
BACKGROUND: During the COVID-19 pandemic, telephone hotlines of local health authorities in Germany were overloaded due to information requests by the public. OBJECTIVE: Evaluating the use of a COVID-19-specific voicebot (CovBot) in local health authorities in Germany during the COVID-19 pandemic. This study investigates the performance of the CovBot by assessing a perceptible relief of staff in the hotline service. METHODS: This prospective mixed-methods study enrolled local health authorities in Germany from 01 February 2021 to 11 February 2022 to deploy the CovBot, which was mainly designed to answer frequently asked questions...
2023: Digital Health
https://read.qxmd.com/read/37283777/2021-annual-report-of-the-kansas-poison-control-center-at-the-university-of-kansas-health-system
#18
JOURNAL ARTICLE
Stephen L Thornton, Lisa K Oller, Kathy White, Robert Stockdale, Elizabeth Silver
INTRODUCTION: This is the 2021 Annual Report of the Kansas Poison Control Center (KSPCC) at The University of Kansas Health System. The KSPCC serves the state of Kansas 24-hours a day, 365 days a year with certified specialists in poison information and clinical and medical toxicologists. METHODS: Encounters reported to the KSPCC from January 1, 2021 through December 31, 2021 were analyzed. Data recorded includes caller demographics, exposure substance, nature and route of exposure, interventions, medical outcome, disposition, and location of care...
2023: Kansas Journal of Medicine
https://read.qxmd.com/read/37257505/-health-hotline-1450-potentials-in-urban-areas-of-lower-austria-a-retrospective-analysis
#19
JOURNAL ARTICLE
Christoph Schullern, Elisabeth Nöhammer
BACKGROUND: Societal changes (in expectations), efficiency efforts in the health systems and, in some cases, a high need for individual counselling due to low health literacy are difficult to align. Triage hotlines that refer callers to best points of care (POC) are possible solutions. The aim of this study was to analyze the potentials of the Austrian triage hotline 1450 in order to recognize patterns and suggest improvements. METHODS: Data from 01.01.-31.12.2019 from two urban areas of Lower Austria with their top five system diagnoses and five most frequent best POC per city were retrospectively analysed and compared...
May 31, 2023: Das Gesundheitswesen
https://read.qxmd.com/read/37213782/one-for-all-or-all-for-one-an-integrative-review-of-research-on-frequent-callers
#20
JOURNAL ARTICLE
S Skogevall, E Kaminsky, J Håkansson, I K Holmström
OBJECTIVE: Telephone health services is an increasing and integral part of health care in several countries. Callers who call repeatedly, in the current study "frequent callers" are present in all kinds of healthcare services, often constitute a considerable proportion of the total amount of calls and are complicated to help. The aim was to provide a comprehensive overview of research on frequent callers at a variety of telephone health services. METHODS: An integrative literature review...
December 2022: PEC Innov
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