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https://www.readbyqxmd.com/read/28088527/navigation-in-the-electronic-health-record-a-review-of-the-safety-and-usability-literature
#1
REVIEW
Lisette C Roman, Jessica S Ancker, Stephen B Johnson, Yalini Senathirajah
OBJECTIVE: Inefficient navigation in electronic health records has been shown to increase users' cognitive load, which may increase potential for errors, reduce efficiency, and increase fatigue. However, navigation has received insufficient recognition and attention in the electronic health record (EHR) literature as an independent construct and contributor to overall usability. Our aims in this literature review were to (1) assess the prevalence of navigation-related topics within the EHR usability and safety research literature, (2) categorize types of navigation actions within the EHR, (3) capture relationships between these navigation actions and usability principles, and (4) collect terms and concepts related to EHR navigation...
January 11, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28088500/voice-emotion-perception-and-production-in-cochlear-implant-users
#2
REVIEW
N T Jiam, M Caldwell, M L Deroche, M Chatterjee, C J Limb
Voice emotion is a fundamental component of human social interaction and social development. Unfortunately, cochlear implant users are often forced to interface with highly degraded prosodic cues as a result of device constraints in extraction, processing, and transmission. As such, individuals with cochlear implants frequently demonstrate significant difficulty in recognizing voice emotions in comparison to their normal hearing counterparts. Cochlear implant-mediated perception and production of voice emotion is an important but relatively understudied area of research...
January 11, 2017: Hearing Research
https://www.readbyqxmd.com/read/28088055/marijuana-use-disorder-symptoms-among-recent-onset-marijuana-users
#3
Lisa Dierker, William Mendoza, Renee Goodwin, Arielle Selya, Jennifer Rose
BACKGROUND: With recreational marijuana having recently been legalized in a growing number of U.S. states, as well as the increasing support for its legalization among substantial segments of the American public, an understanding of the development of symptoms associated with marijuana use disorders will assist in guiding both education and policy. METHODS: This study examined the prevalence of marijuana use disorder symptoms among a nationally representative sample of recent onset marijuana users ages 12-21 drawn from the National Survey of Drug Use and Health (N=9697)...
January 6, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28088032/oral-cannabidiol-does-not-produce-a-signal-for-abuse-liability-in-frequent-marijuana-smokers
#4
Shanna Babalonis, Margaret Haney, Robert J Malcolm, Michelle R Lofwall, Victoria R Votaw, Steven Sparenborg, Sharon L Walsh
BACKGROUND: Cannabidiol (CBD) is a naturally occurring constituent of the marijuana plant. In the past few years, there has been great interest in the therapeutic effects of isolated CBD and it is currently being explored for numerous disease conditions (e.g., pain, epilepsy, cancer, various drug dependencies). However, CBD remains a Schedule I drug on the U.S. Controlled Substances Act (CSA). Despite its status, there are no well-controlled data available regarding its abuse liability...
December 14, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28086771/naturalistic-study-of-guideline-implementation-tool-use-via-evaluation-of-website-access-and-physician-survey
#5
Melissa J Armstrong, Gary S Gronseth, Richard Dubinsky, Sonja Potrebic, Rebecca Penfold Murray, Thomas S D Getchius, Carol Rheaume, Anna R Gagliardi
BACKGROUND: Clinical guidelines support decision-making at the point-of-care but the onus is often on individual users such as physicians to implement them. Research shows that the inclusion of implementation tools in or with guidelines (GItools) is associated with guideline use. However, there is little research on which GItools best support implementation by individual physicians. The purpose of this study was to investigate naturalistic access and use of GItools produced by the American Academy of Neurology (AAN) to inform future tool development...
January 13, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28081515/distinguishing-subpopulations-of-marijuana-users-with-latent-profile-analysis
#6
Matthew R Pearson, Adrian J Bravo, Bradley T Conner
BACKGROUND: Although marijuana is the most commonly used illicit drug in the United States, little is known about the effects of typical marijuana use patterns and whether there are distinct subgroups of marijuana users. METHODS: The present study used latent profile analysis to determine the number of distinct subgroups of marijuana users in a large sample of college students (n=2129 past month marijuana users across 11 universities). We also examined how these distinct groups differ on several putative risk/protective factors (e...
November 23, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28081262/efficacy-of-statin-treatment-in-early-stage-chronic-kidney-disease
#7
Eun Yeong Cho, Chana Myoung, Hong-Suk Park, Ae Jin Kim, Han Ro, Jae Hyun Chang, Hyun Hee Lee, Wookyung Chung, Ji Yong Jung
Chronic kidney disease (CKD) represents a major medical challenge and frequently coexists with cardiovascular disease (CVD), which can be treated by statin trerapy. However, whether statin treatment affects renal progression and outcomes in CKD patients remains unclear. We retrospectively reviewed CKD patients at Gachon University Gil Medical Center from 2003-2013. From a total of 14,497 CKD patients, 858 statin users were paired with non-users and analyze with propensity score matching was performed. The outcomes of this study were creatinine doubling, renal death, all-cause mortality, and interactive factors for composite outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/28079818/factors-associated-with-syphilis-incidence-in-the-hiv-infected-in-the-era-of-highly-active-antiretrovirals
#8
Mohaned Shilaih, Alex Marzel, Dominique L Braun, Alexandra U Scherrer, Helen Kovari, Jim Young, Alexandra Calmy, Katharine Darling, Manuel Battegay, Matthias Hoffmann, Enos Bernasconi, Maria C Thurnheer, Huldrych F Günthard, Roger D Kouyos
After several years of steady decline, syphilis is reemerging globally as a public health hazard, especially among people living with human immunodeficiency virus (HIV). Syphilis resurgence is observed mainly in men who have sex with men (MSM), yet other transmission groups are affected too. In this manuscript, we study the factors associated with syphilis incidence in the Swiss HIV cohort study in the era of highly effective antiretrovirals. Using parametric interval censored models with fixed and time-varying covariates, we studied the immunological, behavioral, and treatment-related elements associated with syphilis incidence in 3 transmission groups: MSM, heterosexuals, and intravenous drug users...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28078472/using-the-edinburgh-postnatal-depression-scale-for-women-and-men-some-cautionary-thoughts
#9
Stephen Matthey, Francesca Agostini
The objective of the study was to critically consider some of the possible limitations in the Edinburgh Depression Scale (EDS), given that great emphasis is put on the results of this measure within both clinical and research fields. Using findings and discussion points from other studies, as well as from a critical analysis of issues by the authors based upon their clinical and research experience, possible limitations with the scale in nine areas are discussed. Possible limitations include the following: (1) ambiguous items, (2) exclusion of certain types of distress, (3) scoring difficulties, (4) low positive predictive value, (5) frequent use of incorrect cut-off scores, (6) a vast array of validated cut-off scores, (7) validation against a questionable gold-standard, (8) limited anxiety detection and of depressive symptoms in men, and (9) many screen positive women only have transient distress...
January 11, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28076635/prevalence-of-vitamin-b12-deficiency-in-type-2-diabetic-patients-using-metformin-a-cross-sectional-study
#10
Charbel Pereira Damião, Amannda Oliveira Rodrigues, Maria Fernanda Miguens Castellar Pinheiro, Rubens Antunes da Cruz, Gilberto Peres Cardoso, Giselle Fernandes Taboada, Giovanna Aparecida Balarini Lima
CONTEXT AND OBJECTIVE: The prevalence of vitamin B12 deficiency varies from 5.8% to 30% among patients undergoing long-term treatment with metformin. Because of the paucity of data on Brazilian patients, this study aimed to determine the frequency of B12 deficiency and related factors among Brazilian patients with type 2 diabetes mellitus (T2DM) using metformin. DESIGN AND SETTING: Cross-sectional study at a public university hospital. METHODS: Patients with T2DM and a control group of non-diabetics were included...
November 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28075207/perceived-needs-for-different-components-in-a-rehabilitation-program-among-cancer-survivors-with-chronic-fatigue-compared-to-survivors-without-chronic-fatigue
#11
Gunhild M Gjerset, Jon H Loge, Cecilie E Kiserud, Sophie D Fosså, Sævar B Gudbergsson, Line M Oldervoll, Torbjørn Wisløff, Lene Thorsen
BACKGROUND: Knowledge about the user' needs is important to develop targeted rehabilitation for cancer patients with chronic fatigue (CF). The aims of the study were to examine prevalence of CF in cancer survivors attending an one-week inpatient educational program (IEP) and to identify characteristics of those with CF. Further to examine the perceived needs for different components in a rehabilitation program, need of complex rehabilitation (at least two components) and aspects of health-related quality of life (HRQoL) among survivors with CF versus those without CF...
January 11, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28074173/radiological-clinical-trials-proposal-of-a-problem-finding-questionnaire-to-improve-study-success
#12
Francesca Valdora, Bianca Bignotti, Massimo Calabrese, Nehmat Houssami, Alberto Tagliafico
AIM: To develop a survey to help define the main problems in radiological clinical trials. METHODS: Since 2006, we have managed seven different radiological clinical trials recruiting patients in academic and non-academic centres. We developed a preliminary questionnaire using a four-round Delphi approach to identify problems occurring in radiological clinical trials run at our centre. We investigated the recruitment experience, involvement of all multi-disciplinary team members and main obstacles to completing the projects...
December 26, 2016: World Journal of Methodology
https://www.readbyqxmd.com/read/28074109/improvement-of-quality-of-life-through-glycemic-control-by-liraglutide-a-glp-1-analog-in-insulin-naive-patients-with-type-2-diabetes-mellitus-the-page1-study
#13
Hitoshi Ishii, Tetsuji Niiya, Yasuhiro Ono, Naoyuki Inaba, Hideaki Jinnouchi, Hirotaka Watada
BACKGROUND: In addition to achieving good glycemic control, diabetes care management aims to improve the quality of life (QOL) in patients. Treatment-associated difficulties and side effects frequently cause deterioration in QOL. Liraglutide, a GLP-1 receptor agonist, is a novel injection drug that promotes insulin secretion. It is a user-friendly, once-daily injection with fewer hypoglycemic events. In this study, we aimed to examine the effect of liraglutide therapy on QOL in patients...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28073947/redefining-the-child-pedestrian-safety-paradigm-identifying-high-fatality-concentrations-in-urban-areas
#14
Nicholas N Ferenchak, Wesley E Marshall
OBJECTIVES: Child pedestrians are some of the most vulnerable users of our transportation systems, and they deserve particular attention when we consider traffic safety. The objective of this work is to identify urban locations in which child pedestrians are at particular risk for fatal collisions with vehicles. METHODS: This paper examines 30 years of crash data for six American cities to locate areas with high child pedestrian fatality concentrations. Phase I of the study, which examines Denver, Colorado, USA, reveals higher concentrations of child pedestrian fatalities around parks as compared with other areas that children have been shown to frequent...
January 10, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28073049/iodine-nutritional-status-and-thyroid-effects-of-exposure-to-ethylenebisdithiocarbamates
#15
Emanuela Medda, Ferruccio Santini, Simona De Angelis, Fabrizio Franzellin, Carla Fiumalbi, Andrea Perico, Enzo Gilardi, Maria Teresa Mechi, Alessandro Marsili, Angela Citroni, Adaniele Leandri, Alberto Mantovani, Paolo Vitti, Antonella Olivieri
INTRODUCTION: Italy is still characterized by a mild iodine deficiency and is among the most intensive users of chemical products for agriculture in Europe. The aim of this study was i) to evaluate thyroid effects of exposure to mancozeb, a fungicide widely used in agriculture, in a sample of Italian grapevine workers, and ii) to verify whether the iodine intake may modulate the risk of thyroid disruption due to the mancozeb metabolite ethylenthiourea (ETU). METHODS: One hundred seventy-seven occupationally exposed male workers (29 from Chianti, a mild iodine deficient area, and 148 from Bolzano an iodine sufficient province) and 74 non-occupationally exposed male controls (34 from Chianti and 40 from Bolzano) were enrolled in the study...
January 7, 2017: Environmental Research
https://www.readbyqxmd.com/read/28072524/common-hits-approach-combining-pharmacophore-modeling-and-molecular-dynamics-simulations
#16
Marcus Wieder, Arthur Garon, Ugo Perricone, Stefan Boresch, Thomas Seidel, Anna Maria Almerico, Thierry Langer
We present a new approach that incorporates flexibility based on extensive MD simulations of protein-ligand complexes into structure based pharmacophore modeling and virtual screening. The approach uses the multiple coordinate sets saved during the MD simulations and generates for each frame a pharmacophore model. Pharmacophore models with the same pharmacophore features are pooled. In this way the high number of pharmacophore models that results from the MD simulation is reduced to only a few hundred representative pharmacophore models...
January 10, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28069618/adherence-to-guidelines-for-creatinine-and-potassium-monitoring-and-discontinuation-following-renin-angiotensin-system-blockade-a-uk-general-practice-based-cohort-study
#17
Morten Schmidt, Kathryn E Mansfield, Krishnan Bhaskaran, Dorothea Nitsch, Henrik Toft Sørensen, Liam Smeeth, Laurie A Tomlinson
OBJECTIVES: To examine adherence to serum creatinine and potassium monitoring and discontinuation guidelines following initiation of treatment with ACE inhibitors (ACEI) or angiotensin receptor blockers (ARBs); and whether high-risk patients are monitored. DESIGN: A general practice-based cohort study using electronic health records from the UK Clinical Practice Research Datalink and Hospital Episode Statistics. SETTING: UK primary care, 2004-2014...
January 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28068828/key-differences-in-treatment-seeking-stimulant-users-attending-a-specialised-treatment-service-a-means-of-early-intervention
#18
Shalini Arunogiri, Margret Petrie, Michelle Sharkey, Dan I Lubman
OBJECTIVES: Few people who use stimulants seek clinical treatment. This study sought to describe a cohort of stimulant users who attended a stimulant-specific treatment service, Access Point, in Melbourne, Australia between 2008 and 2014. METHODS: A retrospective audit of the records of adults ( n = 175) who sought treatment for stimulant use at a stimulant-specific outpatient treatment service was conducted. RESULTS: Service users had a median age of 32 (range = 19-54)...
January 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28065773/using-the-electronic-medical-record-to-identify-patients-at-high-risk-for-frequent-ed-visits-and-high-system-costs
#19
David W Frost, Shankar Vembu, Jiayi Wang, Karen Tu, Quaid Morris, Howard B Abrams
BACKGROUND: A small proportion of patients accounts for a very high proportion of healthcare utilization. Accurate pre-emptive identification may facilitate tailored intervention. We sought to determine whether Machine Learning techniques using text from a family practice Electronic Medical Record (EMR) can be used to predict future high Emergency Department (ED) use and total costs by patients who are not yet high ED users or high cost to the healthcare system. METHODS: Text from fields of the Cumulative Patient Profile within an EMR (PS Suite) of 43,111 patients was indexed...
January 5, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28063513/associations-between-yoga-meditation-use-body-satisfaction-and-weight-management-methods-results-of-a-national-cross-sectional-survey-of-8009-australian-women
#20
Romy Lauche, David Sibbritt, Thomas Ostermann, Nicholas R Fuller, Jon Adams, Holger Cramer
OBJECTIVES: To analyze whether yoga or meditation use is associated with body (dis)satisfaction and weight control methods in Australian women. METHODS: Women ages 34 to 39 y from the Australian Longitudinal Study on Women's Health were surveyed regarding body satisfaction, weight control behaviors, and yoga and meditation practice. Associations of body satisfaction and weight control methods with yoga/meditation practice were analyzed using chi-squared tests and multiple logistic regression modelling...
February 2017: Nutrition
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