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https://www.readbyqxmd.com/read/28229110/reliability-of-the-chronic-mild-stress-model-of-depression-a-user-survey
#1
Paul Willner
The chronic mild stress (CMS) model of depression is considered by many to be the animal model of depression that has the greatest validity and translational potential, but it has often been criticized for a perceived lack of reliability. The aims of this study were to establish the extent to which the procedure is reproducible, and to identify experimental variables relevant to its reliability. Because failures to replicate frequently remain unpublished, a survey methodology was used. A questionnaire was circulated to 170 labs identified from a PubMed search as having published a CMS study in the years 2010 or 2015 (with no selection in respect of the results reported)...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28228094/sfreemap-a-simulation-free-tool-for-stochastic-mapping
#2
Diego Pasqualin, Marcos Barbeitos, Fabiano Silva
BACKGROUND: Stochastic mapping is frequently used in comparative biology to simulate character evolution, enabling the probabilistic computation of statistics such as number of state transitions along a tree and distribution of states in its internal nodes. Common implementations rely on Continuous-time Markov Chain simulations whose parameters are difficult to adjust and subjected to inherent inaccuracy. Thus, researchers must run a large number of simulations in order to obtain adequate estimates...
February 22, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28227781/measuring-the-intuitive-response-of-users-when-faced-with-different-interactive-paradigms-to-control-a-gastroenterology-cad-system
#3
D Abrantes, P Gomes, D Pereira, M Coimbra, D Abrantes, P Gomes, D Pereira, M Coimbra, D Pereira, D Abrantes, P Gomes, M Coimbra
The gastroenterology specialty could benefit from the introduction of Computer Assisted Decision (CAD) systems, since gastric cancer is a serious concern in which an accurate and early diagnosis usually leads to a good prognosis. Still, the way doctors interact with these systems is very important because it will often determine its embracement or rejection, as any gains in productivity will frequently hinge on how comfortable they are with it. Using other types of interaction paradigms such as voice and motion control, is important in a way that typical inputs such as keyboard and mouse are sometimes not the best choice for certain clinical scenarios...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227654/preliminary-results-for-an-adaptive-pattern-recognition-system-for-novel-users-using-a-powered-lower-limb-prosthesis
#4
John A Spanias, Ann M Simon, Eric J Perreault, Levi J Hargrove, John A Spanias, Ann M Simon, Eric J Perreault, Levi J Hargrove, Eric J Perreault, John A Spanias, Ann M Simon, Levi J Hargrove
Powered prosthetic legs are capable of improving the gait of lower limb amputees. Pattern recognition systems for these devices allow amputees to transition between different locomotion modes in a way that is seamless and transparent to the user. However, the potential of these systems is diminished because they require large amounts of training data that is burdensome to collect. To reduce the effort required to acquire these data, we developed an adaptive pattern recognition system that automatically learns from subject-specific data as the user is ambulating...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226908/s2ni-a-mobile-platform-for-nutrition-monitoring-from-spoken-data
#5
Niloofar Hezarjaribi, Cody A Reynolds, Drew T Miller, Naomi Chaytor, Hassan Ghasemzadeh, Niloofar Hezarjaribi, Cody A Reynolds, Drew T Miller, Naomi Chaytor, Hassan Ghasemzadeh, Hassan Ghasemzadeh, Cody A Reynolds, Naomi Chaytor, Niloofar Hezarjaribi, Drew T Miller
Diet and physical activity are important lifestyle and behavioral factors in self-management and prevention of many chronic diseases. Mobile sensors such as accelerometers have been used in the past to objectively measure physical activity or detect eating time. Diet monitoring, however, still relies on self-recorded data by end users where individuals use mobile devices for recording nutrition intake by either entering text or taking images. Such approaches have shown low adherence in technology adoption and achieve only moderate accuracy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222759/development-and-assessment-of-a-hand-assist-device-gripit
#6
Byungchul Kim, Hyunki In, Dae-Young Lee, Kyu-Jin Cho
BACKGROUND: Although various hand assist devices have been commercialized for people with paralysis, they are somewhat limited in terms of tool fixation and device attachment method. Hand exoskeleton robots allow users to grasp a wider range of tools but are heavy, complicated, and bulky owing to the presence of numerous actuators and controllers. The GRIPIT hand assist device overcomes the limitations of both conventional devices and exoskeleton robots by providing improved tool fixation and device attachment in a lightweight and compact device...
February 21, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28219487/evidence-for-the-risks-and-consequences-of-adolescent-cannabis-exposure
#7
REVIEW
Amir Levine, Kelly Clemenza, Moira Rynn, Jeffrey Lieberman
OBJECTIVE: This review of the scientific literature examines the potential adult sequelae of exposure to cannabis and related synthetic cannabinoids in adolescence. We examine the four neuropsychiatric outcomes that are likely most vulnerable to alteration by early cannabinoid use, as identified within both the clinical and preclinical research: cognition, emotional functioning, risk for psychosis, and addiction. METHOD: A literature search was conducted through PubMed, PsychInfo, and Google Scholar with no publication date restrictions...
March 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28218972/views-of-oral-antibiotics-and-advice-seeking-about-acne-a-qualitative-study-of-online-discussion-forums
#8
M Santer, D Chandler, M Lown, N A Francis, I Muller
BACKGROUND: Acne vulgaris is common and can significantly impair quality of life, yet little is known about patients' understanding of acne and its treatments. Oral antibiotics are widely used for acne, despite concerns about antibiotic resistance. People are increasingly turning to online discussion forums for advice and information on these sites may influence health beliefs and treatment adherence. OBJECTIVE: To explore understandings about the use of oral antibiotics for acne and advice shared amongst messages posted on online forums...
February 20, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28210351/cross-continuum-tool-is-associated-with-reduced-utilization-and-cost-for-frequent-high-need-users
#9
Lauran Hardin, Adam Kilian, Leslie Muller, Kevin Callison, Michael Olgren
INTRODUCTION: High-need, high-cost (HNHC) patients can over-use acute care services, a pattern of behavior associated with many poor outcomes that disproportionately contributes to increased U.S. healthcare cost. Our objective was to reduce healthcare cost and improve outcomes by optimizing the system of care. We targeted HNHC patients and identified root causes of frequent healthcare utilization. We developed a cross-continuum intervention process and a succinct tool called a Complex Care Map (CCM)© that addresses fragmentation in the system and links providers to a comprehensive individualized analysis of the patient story and causes for frequent access to health services...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28208610/non-emergency-medical-transportation-needs-of-middle-aged-and-older-adults-a-rural-urban-comparison-in-delaware-usa
#10
Matthew Lee Smith, Thomas R Prohaska, Kara E MacLeod, Marcia G Ory, Amy R Eisenstein, David R Ragland, Cheryl Irmiter, Samuel D Towne, William A Satariano
Background: Older adults in rural areas have unique transportation barriers to accessing medical care, which include a lack of mass transit options and considerable distances to health-related services. This study contrasts non-emergency medical transportation (NEMT) service utilization patterns and associated costs for Medicaid middle-aged and older adults in rural versus urban areas. Methods: Data were analyzed from 39,194 NEMT users of LogistiCare-brokered services in Delaware residing in rural (68.3%) and urban (30...
February 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28207946/a-systematic-review-of-the-psychometric-properties-of-instruments-for-assessing-the-quality-of-the-physical-environment-in-healthcare
#11
REVIEW
Marie Elf, Susanna Nordin, Helle Wijk, Kevin J McKee
AIM: To identify instruments measuring the quality of the physical healthcare environment, describe their psychometric properties. BACKGROUND: The physical healthcare environment is regarded as a quality factor for healthcare. To facilitate evidence-based design there is a need for valid and usable instruments that can evaluate the design of the healthcare environment. DESIGN: Systematic psychometric review. DATA SOURCES: A systematic literature search in Medline, CINAHL, Psychinfo, Avery index and reference lists of eligible papers (1990-2016)...
February 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28203078/a-survey-of-emedia-delivered-interventions-for-schizophrenia-used-in-randomized-controlled-trials
#12
Farooq Naeem, Tariq Munshi, Shuo Xiang, Megan Yang, Farhad Shokraneh, Yumeen Syed, Muhammad Ayub, Clive E Adams, Saeed Farooq
BACKGROUND: Randomized trials evaluating electronic Media (eMedia) delivery of interventions are increasingly frequent in mental health. Although a number of reviews have reported efficacy of these interventions, none has reviewed the type of eMedia interventions and quality of their description. We therefore decided to conduct a survey of eMedia-delivered interventions for schizophrenia. METHODS: We surveyed all relevant trials reliably identified in the Cochrane Schizophrenia Group's comprehensive register of trials by authors working independently...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28198993/a-debate-can-we-recommend-electronic-cigarettes-to-our-patients-opinion-2
#13
Michał Poznański, Tadeusz Pietras, Adam Antczak
Electronic cigarettes are more and more frequently used to deliver nicotine. They are used both by the users of regular cigarettes and those who to date have not smoked. The literature about potential impact of electronic nicotine delivery systems on health is constantly growing. Particular concern is expressed about toxicity of chemical compounds and elements delivered with the vapour of electronic cigarettes. It turns out that products that have positive image in media, actually are not so beneficial. Furthermore, they not only may cause damage to health but also death...
2017: Adv Respir Med
https://www.readbyqxmd.com/read/28198988/e-smoking-among-students-of-medicine-frequency-pattern-and-motivations
#14
Grzegorz Brożek, Mateusz Jankowski, Jan Zejda, Agnieszka Jarosińska, Agnieszka Idzik, Piotr Bańka
INTRODUCTION: E-smoking has become a public health problem. The objectives of this study were to assess the prevalence of e-cigarette and tobacco cigarette use; to compare the patterns of smoking; to assess the attitudes and motivations for e-cigarette use. MATERIAL AND METHODS: All 1,700 students from Faculty of Medicine (Medical University of Silesia) were invited to questionnaire based cross-sectional study about the frequency and attitudes towards the use of traditional and electronic cigarettes...
2017: Adv Respir Med
https://www.readbyqxmd.com/read/28196995/injection-drug-use-among-children-and-adolescents-in-india-ringing-the-alarm-bells
#15
Anju Dhawan, Raman Deep Pattanayak, Anita Chopra, Vinod Kumar Tikoo, Rajesh Kumar
INTRODUCTION: Injection drug use (IDU) is intricately linked to preventive aspects for human immunodeficiency virus from a public health perspective. No large-scale data are yet available for injectable drug use among children and adolescents in India, apart from few anecdotal reports. AIMS AND METHODS: The present paper reports on the profile and substance use pattern of 509 child IDU users, among a total sample of over 4000 children using substances across 100 sites from 27 states and 2 UTs in India...
October 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28196680/trajectories-of-substance-use-frequency-among-adolescents-seen-in-primary-care-implications-for-screening
#16
Scott E Hadland, Sarah H Copelas, Sion K Harris
OBJECTIVE: To identify trajectories of substance use in a prospective cohort of adolescent primary care patients one year after a clinic visit. STUDY DESIGN: We recruited 12- to 18-year-olds from 9 New England practices between 2005 and 2008 and identified 5 trajectories of substance use. We first distinguished adolescents with no past-year use at a baseline clinic visit and at 12-month follow-up (trajectory A). For adolescents who used substances, we assessed past 90-day use at both timepoints, and identified the remaining 4 trajectories based on frequency of use...
February 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28194082/internet-use-at-workplaces-and-its-effects-on-working-style-in-indian-context-an-exploration
#17
Apoorva Shrivastava, Manoj K Sharma, P Marimuthu
BACKGROUND: Internet use has revolutionized the pattern of working style at the workplace. It led to an increased use for nonprofessional activities at the workplace. It has been shown to affect productivity at the workplace. There is a dearth of literature from the Indian context in this area. AIM: This study was conducted to explore the pattern of Internet use at the workplace and its dysfunctions. SETTING AND DESIGN: The present study was a cross-sectional prospective study...
May 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28188722/prevalence-of-hypokalemia-before-and-after-bowel-preparation-for-colonoscopy-in-high-risk-patients
#18
Ankie Reumkens, Ad A M Masclee, Bjorn Winkens, Cees T van Deursen, Silvia Sanduleanu, C Minke Bakker
BACKGROUND AND AIMS: Bowel preparation for colonoscopy should not cause significant shifts in systemic electrolyte concentrations. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal consequences, prompting us to conduct a study to explore the magnitude of and risk factors for hypokalemia associated with bowel preparation. We paid specific attention to higher risk subgroups, in particular diuretic users, hospitalized patients and patients estimated at to be high risk by the gastroenterologist...
February 7, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28187296/toxicological-investigation-of-forensic-cases-related-to-the-designer-drug-3-4-methylenedioxypyrovalerone-mdpv-detection-quantification-and-studies-on-human-metabolism-by-gc-ms
#19
Marcel Grapp, Christoph Kaufmann, Martin Ebbecke
3,4-methylenedioxypyrovalerone (MDPV) is a synthetic cathinone belonging to the class of α-pyrrolidinophenones that become increasingly popular as a designer psychostimulant. Here, we report a comprehensive collection of MDPV exposure with quantitative serum level confirmation in Germany. During the years 2014-2016, we could proof consumption of MDPV in 23 cases where urine and blood samples were submitted to our laboratory by the police of Lower Saxony. Most of the samples underwent systematic toxicological analysis by gas chromatography-mass spectrometry (GC-MS), where MDPV could be detected in urine and/or serum samples...
February 2, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28183689/game-based-rehabilitation-for-myoelectric-prosthesis-control
#20
Cosima Prahm, Ivan Vujaklija, Fares Kayali, Peter Purgathofer, Oskar C Aszmann
BACKGROUND: A high number of upper extremity myoelectric prosthesis users abandon their devices due to difficulties in prosthesis control and lack of motivation to train in absence of a physiotherapist. Virtual training systems, in the form of video games, provide patients with an entertaining and intuitive method for improved muscle coordination and improved overall control. Complementary to established rehabilitation protocols, it is highly beneficial for this virtual training process to start even before receiving the final prosthesis, and to be continued at home for as long as needed...
February 9, 2017: JMIR Serious Games
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