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https://www.readbyqxmd.com/read/28526997/nafld-as-a-sexual-dimorphic-disease-role-of-gender-and-reproductive-status-in-the-development-and-progression-of-nonalcoholic-fatty-liver-disease-and-inherent-cardiovascular-risk
#1
REVIEW
Stefano Ballestri, Fabio Nascimbeni, Enrica Baldelli, Alessandra Marrazzo, Dante Romagnoli, Amedeo Lonardo
Nonalcoholic fatty liver disease (NAFLD) spans steatosis through nonalcoholic steatohepatis, cirrhosis, and hepatocellular carcinoma (HCC) associated with striking systemic features and excess cardiovascular and liver-related mortality. The pathogenesis of NAFLD is complex and multifactorial. Endocrine derangements are closely linked with dysmetabolic traits. For example, in animal and human studies, female sex is protected from dysmetabolism thanks to young individuals' ability to partition fatty acids towards ketone body production rather than very low density lipoprotein (VLDL)-triacylglycerol, and to sex-specific browning of white adipose tissue...
May 19, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28525295/duration-of-reproductive-years-and-the-risk-of-cardiovascular-and-cerebrovascular-events-in-older-women-insights-from-the-national-health-and-nutrition-examination-survey
#2
Hend Mansoor, Islam Y Elgendy, Richard Segal, Abraham Hartzema
BACKGROUND: Studies have shown conflicting information regarding the association between the age at menarche and/or menopause and cardiovascular and cerebrovascular diseases in older women. This study aimed to determine whether a longer duration of reproductive years in older women in the U.S. population was associated with a lower risk of cardiovascular and cerebrovascular diseases. MATERIALS AND METHODS: Women ≥60 years who participated in the National Health and Nutrition Examination Survey from 2007 to 2012 were included...
May 19, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28521890/reproductive-factors-and-incidence-of%C3%A2-heart-failure-hospitalization-in-the%C3%A2-women-s-health%C3%A2-initiative
#3
Philip S Hall, Gregory Nah, Barbara V Howard, Cora E Lewis, Matthew A Allison, Gloria E Sarto, Molly E Waring, Lisette T Jacobson, JoAnn E Manson, Liviu Klein, Nisha I Parikh
BACKGROUND: Reproductive factors reflective of endogenous sex hormone exposure might have an effect on cardiac remodeling and the development of heart failure (HF). OBJECTIVES: This study examined the association between key reproductive factors and the incidence of HF. METHODS: Women from a cohort of the Women's Health Initiative were systematically evaluated for the incidence of HF hospitalization from study enrollment through 2014. Reproductive factors (number of live births, age at first pregnancy, and total reproductive duration [time from menarche to menopause]) were self-reported at study baseline in 1993 to 1998...
May 23, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28520646/relationship-between-pubertal-timing-and-chronic-nonspecific-pain-in-adolescent-girls-the-young-hunt3-study-2006-2008
#4
Barbro Kløven, Gry B Hoftun, Pål R Romundstad, Marite Rygg
The aim of this study was to examine a possible relationship between early puberty and chronic non-specific pain in 13-18 years old girls. All adolescents in Nord-Trøndelag County, Norway, were invited to participate in the Young-HUNT3 study (2006-2008). Of the invited girls 81% answered the questionnaire and of these 3982 were 13-18 years. Menarche and perceived physical maturation were used as exposure measures. Early menarche was defined as <12 years, normal menarche as ≥12 and <14 years, and late menarche as ≥14 years...
May 16, 2017: Pain
https://www.readbyqxmd.com/read/28512241/assessment-of-breast-cancer-risk-factors-reveals-subtype-heterogeneity
#5
Johanna Holm, Louise Eriksson, Alexander Ploner, Mikael Eriksson, Mattias Rantalainen, Jingmei Li, Per Hall, Kamila Czene
Subtype heterogeneity for breast cancer risk factors has been suspected, potentially reflecting etiological differences and implicating risk prediction. However, reports are conflicting regarding presence of heterogeneity for many exposures. To examine subtype heterogeneity across known breast cancer risk factors, we conducted a case-control analysis of 2,632 breast cancers and 15,945 controls in Sweden. Molecular subtype was predicted from pathology-record derived immunohistochemistry markers by a classifier trained on PAM50 subtyping...
May 16, 2017: Cancer Research
https://www.readbyqxmd.com/read/28508614/methods-for-rating-sexual-development-in-girls
#6
Vincenzo De Sanctis, Ihab Zaki Elhakim, Ashraf T Soliman, Heba Elsedfy, Rania Elalaily, Giuseppe Millimaggi
Sexual maturity rating (SMR) is important in population studies and in clinical care. Pubertal staging allows doctors to assess the maturation of adolescents to correlate several pubertal phenomena such as age at menarche, growth spurt and final height, to advise and manage patients appropriately and to have sensitive "sensors" of the effects of environmental exposure on human populations. The commonly used markers of the timing of female puberty are thelarche and menarche. Appearance of the breast bud is the first indicator of puberty onset in 90% of girls...
September 2016: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28507639/comparative-assessment-of-women-s-reproductive-health-in-the-areas-bordering-with-the-aral-sea-region
#7
Yasminur G Turdybekova, Irina L Kopobayeva, Berikbay Zh Kultanov
AIM: We examined 435 women of Aktobe region and 328 women of South Kazakhstan region, living in areas bordering the Aral Sea region during the study and comparative assessment of the impact of climatic and anthropogenic factors of Aral region on the reproductive health of the female population. MATERIAL AND METHODS: The survey based on the comprehensive clinical-functional and laboratory studies accounting the regional and environmental ecological factors. Survey subject was the area of 2 settlements of Aktobe region and 1 settlement of South Kazakhstan region...
April 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28504464/skeletal-maturity-of-the-hand-in-an-east-african-group-from-sudan
#8
Fadil Elamin, Nihal Abdelazeem, Ahmed Elamin, Duaa Saif, Helen M Liversidge
OBJECTIVES: Studies of skeletal maturity from Africa indicate a delay, reflected in a negative relative skeletal age (RSA). This study aims to evaluate the influence of age, socioeconomic status (SES) and nutritional status on skeletal maturation in a large sample of children from North Sudan. MATERIALS: The sample consisted 665 males and 1018 females from 3-25 years from Khartoum. Height, weight, age of menarche and, SES were recorded of patients attending for dental treatment...
May 15, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28501319/association-of-pyrethroids-exposure-with-onset-of-puberty-in-chinese-girls
#9
Xiaoqing Ye, Wuye Pan, Yuehao Zhao, Shilin Zhao, Yimin Zhu, Weiping Liu, Jing Liu
Pyrethroids, a class of ubiquitous insecticides, have been considered as endocrine-disrupting chemicals (EDCs). Female animal studies suggested that early-life pyrethroids exposure might delay puberty onset. However, it remains unclear whether this association applies to human populations. A total of 305 girls at the ages of 9-15 years old were recruited in Hangzhou, China in this study. The concentration of the common metabolite of pyrethroids, 3-phenoxybenzoic acid (3-PBA), was analyzed in urine samples to reflect the exposure level of pyrethroids...
May 10, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28499527/contraception-menarche-to-menopause
#10
REVIEW
Erin E Tracy
Contraception services should be part of routine health care maintenance in reproductive-aged women, especially in light of the fact that approximately 50% of pregnancies in the United States remain unplanned. Barrier methods, especially condoms, may play a role in sexually transmitted disease prevention but are less efficacious for pregnancy avoidance. There are several available hormonal contraceptive options, including the combination hormonal pill, progestin-only pill, combination hormonal patches and rings, injectable progestins, implantable progestins, intrauterine devices (copper or progestin), and permanent sterilization...
June 2017: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/28495176/pubertal-timing-and-cardiometabolic-markers-at-age-16-years
#11
Nina E Berentzen, Alet H Wijga, Lenie van Rossem, Dirkje S Postma, Ulrike Gehring, Henriëtte A Smit
OBJECTIVE: To examine the association between pubertal timing and cardiometabolic markers among adolescents. STUDY DESIGN: We used data from Dutch adolescents participating in a birth cohort study. The study population for the current study consisted of 799 adolescents of whom data were available for at least 1 of the exposure variables (pubertal timing and/or age at menarche) and any of the cardiometabolic markers (waist circumference, cholesterol, blood pressure [BP], glycated hemoglobin) measured at age 16 years...
May 8, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28487778/cl-ii-malocclusion-treatment-using-the-modified-twin-block-appliance-coordinated-with-fixed-orthodontics-in-a-postmenarche-patient
#12
Amin Aminian, Shahriar Sarvareh Azimzadeh, Elina Rahmanian
Functional appliances have been used for treatment of Class II patients for a long time. The main objective of therapy with functional appliances is to induce supplementary lengthening of the mandible by stimulating increased growth at the condylar cartilage. The Twin Block appliance is one of the most commonly used functional appliances. The aim of this paper is to present a case report of mandibular deficiency treatment with Twin Block appliance in a female patient whose sexual maturation (one and a half years after menarche) and cervical vertebral maturation stage indicated the end of the growth peak...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28486542/association-between-menarche-and-iron-deficiency-in-non-anemic-young-women
#13
Deepa L Sekhar, Laura E Murray-Kolb, Allen R Kunselman, Carol S Weisman, Ian M Paul
BACKGROUND: The prevalence of iron deficiency (ID) among non-pregnant, reproductive-age US women significantly exceeds rates among males. In clinical practice ID screening relies on hemoglobin, a late-stage indicator of ID. As a single, low-cost laboratory test to diagnose ID before anemia develops is lacking, the study objective was to improve ID screening by identifying risk factors among non-anemic, iron-deficient reproductive age women. METHODS: Cross-sectional data were from the National Health and Nutrition Examination Survey (NHANES) 2003-2010...
2017: PloS One
https://www.readbyqxmd.com/read/28485514/incidence-puberty-and-fertility-in-45-x-47-xxx-mosaicism-report-of-a-patient-and-a-literature-review
#14
Han Hyuk Lim, Hong Ryang Kil, Sun Hoe Koo
Turner syndrome (TS), characterized by short stature and premature ovarian failure, is caused by chromosomal aberrations with total or partial loss of one of the two X chromosomes. Spontaneous puberty, menarche, and pregnancy occur in some patients depending on the abnormality of the X. Moreover, spontaneous pregnancy is uncommon (<0.5%) for TS with 45,X monosomy. Among TS patients, 45,X/47,XXX karyotype is extremely rare. Previous reports have demonstrated that TS with 45,X/47,XXX is less severe than common TS due to higher occurrence of puberty (83%), menarche (57-67%), and fertility (14%) and lower occurrence of congenital anomalies (<5%)...
May 9, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28482934/longevity-in-north-korea-and-south-korea-prevalence-of-centenarians-in-one-the-poorest-and-one-of-the-richest-nations
#15
Daniel Schwekendiek
Over recent decades, economic living conditions have dramatically improved in South Korea, which now represents one of the most developed nations. At the same time, its twin in the North remains one of the poorest countries on earth. Thus, the Korean peninsula represents a unique historical experiment that allows for study of the effects of environment on human development under a variety of ceteris paribus cultural, genetic and climatic conditions. Previous studies comparing the biosocial performances of the two Koreas have focused on indicators such as weight, height, mid-upper arm circumference and age at menarche...
May 9, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28478835/the-hormonal-sensitivity-hypothesis-a-review-and-new-findings
#16
Carley J Pope, Kirsten Oinonen, Dwight Mazmanian, Suzanne Stone
Previous women's health practitioners and researchers have postulated that some women are particularly sensitive to hormonal changes occurring during reproductive events. We hypothesize that some women are particularly sensitive to hormonal changes occurring across their reproductive lifespan. To evaluate this hypothesis, we reviewed findings from the existing literature and findings from our own lab. Taken together, the evidence we present shows a recurring pattern of hormonal sensitivity at predictable but different times across the lifespan of some women (i...
May 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28469738/herlyn-werner-wunderlich-syndrome-sonographic-and-magnetic-resonance-mr-imaging-findings-of-this-rare-urogenital-anomaly
#17
Sukriye Yilmaz, Adalet Elcin Yildiz, Suat Fitoz
BACKGROUND: Herlyn-Werner-Wunderlich syndrome is a rare congenital urogenital anomaly characterised by uterus didelphys with blind hemivagina and ipsilateral renal agenesis. Children usually have progressive pelvic pain after menarche, palpable mass due to hemihaemato(metro)colpos or pelvic inflammatory disease. The diagnosis usually requires a suspicion of this rare genitourinary syndrome. CASE REPORTS: We present ultrasonography and MR imaging findings of this rare anomaly in two cases...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28456695/paratubal-cyst-size-correlates-with-obesity-and-dysregulation-of-the-wnt-signaling-pathway
#18
Jennifer E Dietrich, Oluyemisi Adeyemi, Julie Hakim, Xiomara Santos, Jennifer L Bercaw-Pratt, Juan C Bournat, Ching H Chen, Carolina J Jorgez
BACKGROUND: Paratubal cysts (PTC) occur in 7-10% of females, regardless of ages. Although common, PTCs often are found incidentally because of the potential for these cysts to be asymptomatic. SPECIFIC AIMS: To determine if PTC number and size correlated with signs of hyperandrogenism and obesity, as well as to investigate the molecular profiles of these PTCs in samples derived from adolescent females. METHODS: A prospective cohort study was performed in a single children's hospital...
April 26, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28447568/age-at-menarche-in-relation-to-prenatal-rainy-season-exposure-and-altitude-of-residence-results-from-a-nationally-representative-survey-in-a-tropical-country-erratum
#19
E C Jansen, O F Herrán, N L Fleischer, A M Mondul, E Villamor
No abstract text is available yet for this article.
June 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28447441/a-cutoff-for-age-at-menarche-predicting-metabolic-syndrome-in-egyptian-overweight-obese-premenopausal-women
#20
Ibrahim Elsehely, Hala Abdel Hafez, Mohammed Ghonem, Ali Fathi, Rasha Elzehery
Previous studies showed that early age at menarche is associated with increased risk of metabolic syndrome. However, the definition of early menarche at these studies was based on background data in the communities at which these studies was carried on. The aim of this work is to determine a cutoff for age at menarche discriminating presence or absence of metabolic syndrome in overweight/obese premenopausal women. This study included 204 overweight/obese women. Metabolic syndrome was defined according to NCEP-ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria...
April 2017: Diabetes & Metabolism Journal
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