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https://www.readbyqxmd.com/read/28447568/age-at-menarche-in-relation-to-prenatal-rainy-season-exposure-and-altitude-of-residence-results-from-a-nationally-representative-survey-in-a-tropical-country-erratum
#1
E C Jansen, O F Herrán, N L Fleischer, A M Mondul, E Villamor
No abstract text is available yet for this article.
April 27, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28447441/a-cutoff-for-age-at-menarche-predicting-metabolic-syndrome-in-egyptian-overweight-obese-premenopausal-women
#2
Ibrahim Elsehely, Hala Abdel Hafez, Mohammed Ghonem, Ali Fathi, Rasha Elzehery
Previous studies showed that early age at menarche is associated with increased risk of metabolic syndrome. However, the definition of early menarche at these studies was based on background data in the communities at which these studies was carried on. The aim of this work is to determine a cutoff for age at menarche discriminating presence or absence of metabolic syndrome in overweight/obese premenopausal women. This study included 204 overweight/obese women. Metabolic syndrome was defined according to NCEP-ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria...
April 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28445268/the-use-of-mifepristone-in-abortion-associated-with-an-increased-risk-of-uterine-leiomyomas
#3
Qi Shen, Li Shu, Hui Luo, Xiaoli Hu, Xueqiong Zhu
To investigate the association between widespread use of mifepristone in abortions and risk of uterine leiomyomas.We conducted a case-control study of 305 patients with uterine leiomyomas between January 2011 and July 2012; 311 women with ordinary vaginitis were selected as controls during the same period. Data were collected by questionnaires (including past history, life history, menstruation history, reproductive history, abortion history, the use of mifepristone, and uterine leiomyomas risk factors) and calculated by univariate and multivariate conditional logistic regression analyses; odds ratios and its 95% confidence interval were calculated to estimate the risk for uterine leiomyomas...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28440542/menstrual-and-reproductive-factors-and-lung-cancer-risk-a-pooled-analysis-from-the-international-lung-cancer-consortium-ilcco
#4
Soumaya Ben Khedher, Monica Neri, Alexandra Papadopoulos, David C Christiani, Nancy Diao, Curtis C Harris, Susan Olivo-Marston, Ann G Schwartz, Michele Cote, Anita Koushik, Jack Siemiatycki, Maria Teresa Landi, Rayjean J Hung, John McLaughlin, Eric J Duell, Angeline S Andrew, Irene Orlow, Bernard J Park, Hermann Brenner, Kai-Uwe Saum, Angela C Pesatori, Isabelle Stücker
Many clinical features of lung cancer are different in women and men. Sex steroid hormones exert effects in non-reproductive organs, such as the lungs. The association between menstrual and childbearing factors and the risk of lung cancer among women is still debated. We performed a pooled analysis of eight studies contributing to the International Lung Cancer Consortium (ILCCO; 4,386 cases and 4,177 controls). Pooled associations between menstrual or reproductive factors and lung cancer were estimated using multivariable unconditional logistic regression...
April 25, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28439312/validation-of-the-multiplier-method-for-leg-length-predictions-on-a-large-european-cohort-and-an-assessment-of-the-effect-of-physiological-age-on-predictions
#5
J J Aird, C L Cheesman, A T Schade, F P Monsell
PURPOSE: The Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort was used to determine the accuracy of the Paley multiplier method for predicting leg length. Using menarche as a proxy, physiological age was then used to increase the accuracy of the multiplier. METHODS: Chronological age was corrected in female patients over the age of eight years with documented date of first menses. Final sub-ischial leg length and predicted final leg length were predicted for all data points...
2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28436984/genomic-analyses-identify-hundreds-of-variants-associated-with-age-at-menarche-and-support-a-role-for-puberty-timing-in-cancer-risk
#6
Felix R Day, Deborah J Thompson, Hannes Helgason, Daniel I Chasman, Hilary Finucane, Patrick Sulem, Katherine S Ruth, Sean Whalen, Abhishek K Sarkar, Eva Albrecht, Elisabeth Altmaier, Marzyeh Amini, Caterina M Barbieri, Thibaud Boutin, Archie Campbell, Ellen Demerath, Ayush Giri, Chunyan He, Jouke J Hottenga, Robert Karlsson, Ivana Kolcic, Po-Ru Loh, Kathryn L Lunetta, Massimo Mangino, Brumat Marco, George McMahon, Sarah E Medland, Ilja M Nolte, Raymond Noordam, Teresa Nutile, Lavinia Paternoster, Natalia Perjakova, Eleonora Porcu, Lynda M Rose, Katharina E Schraut, Ayellet V Segrè, Albert V Smith, Lisette Stolk, Alexander Teumer, Irene L Andrulis, Stefania Bandinelli, Matthias W Beckmann, Javier Benitez, Sven Bergmann, Murielle Bochud, Eric Boerwinkle, Stig E Bojesen, Manjeet K Bolla, Judith S Brand, Hiltrud Brauch, Hermann Brenner, Linda Broer, Thomas Brüning, Julie E Buring, Harry Campbell, Eulalia Catamo, Stephen Chanock, Georgia Chenevix-Trench, Tanguy Corre, Fergus J Couch, Diana L Cousminer, Angela Cox, Laura Crisponi, Kamila Czene, George Davey Smith, Eco J C N de Geus, Renée de Mutsert, Immaculata De Vivo, Joe Dennis, Peter Devilee, Isabel Dos-Santos-Silva, Alison M Dunning, Johan G Eriksson, Peter A Fasching, Lindsay Fernández-Rhodes, Luigi Ferrucci, Dieter Flesch-Janys, Lude Franke, Marike Gabrielson, Ilaria Gandin, Graham G Giles, Harald Grallert, Daniel F Gudbjartsson, Pascal Guénel, Per Hall, Emily Hallberg, Ute Hamann, Tamara B Harris, Catharina A Hartman, Gerardo Heiss, Maartje J Hooning, John L Hopper, Frank Hu, David J Hunter, M Arfan Ikram, Hae Kyung Im, Marjo-Riitta Järvelin, Peter K Joshi, David Karasik, Manolis Kellis, Zoltan Kutalik, Genevieve LaChance, Diether Lambrechts, Claudia Langenberg, Lenore J Launer, Joop S E Laven, Stefania Lenarduzzi, Jingmei Li, Penelope A Lind, Sara Lindstrom, YongMei Liu, Jian'an Luan, Reedik Mägi, Arto Mannermaa, Hamdi Mbarek, Mark I McCarthy, Christa Meisinger, Thomas Meitinger, Cristina Menni, Andres Metspalu, Kyriaki Michailidou, Lili Milani, Roger L Milne, Grant W Montgomery, Anna M Mulligan, Mike A Nalls, Pau Navarro, Heli Nevanlinna, Dale R Nyholt, Albertine J Oldehinkel, Tracy A O'Mara, Sandosh Padmanabhan, Aarno Palotie, Nancy Pedersen, Annette Peters, Julian Peto, Paul D P Pharoah, Anneli Pouta, Paolo Radice, Iffat Rahman, Susan M Ring, Antonietta Robino, Frits R Rosendaal, Igor Rudan, Rico Rueedi, Daniela Ruggiero, Cinzia F Sala, Marjanka K Schmidt, Robert A Scott, Mitul Shah, Rossella Sorice, Melissa C Southey, Ulla Sovio, Meir Stampfer, Maristella Steri, Konstantin Strauch, Toshiko Tanaka, Emmi Tikkanen, Nicholas J Timpson, Michela Traglia, Thérèse Truong, Jonathan P Tyrer, André G Uitterlinden, Digna R Velez Edwards, Veronique Vitart, Uwe Völker, Peter Vollenweider, Qin Wang, Elisabeth Widen, Ko Willems van Dijk, Gonneke Willemsen, Robert Winqvist, Bruce H R Wolffenbuttel, Jing Hua Zhao, Magdalena Zoledziewska, Marek Zygmunt, Behrooz Z Alizadeh, Dorret I Boomsma, Marina Ciullo, Francesco Cucca, Tõnu Esko, Nora Franceschini, Christian Gieger, Vilmundur Gudnason, Caroline Hayward, Peter Kraft, Debbie A Lawlor, Patrik K E Magnusson, Nicholas G Martin, Dennis O Mook-Kanamori, Ellen A Nohr, Ozren Polasek, David Porteous, Alkes L Price, Paul M Ridker, Harold Snieder, Tim D Spector, Doris Stöckl, Daniela Toniolo, Sheila Ulivi, Jenny A Visser, Henry Völzke, Nicholas J Wareham, James F Wilson, Amanda B Spurdle, Unnur Thorsteindottir, Katherine S Pollard, Douglas F Easton, Joyce Y Tung, Jenny Chang-Claude, David Hinds, Anna Murray, Joanne M Murabito, Kari Stefansson, Ken K Ong, John R B Perry
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated with various adult diseases. Using 1000 Genomes Project-imputed genotype data in up to ∼370,000 women, we identify 389 independent signals (P < 5 × 10(-8)) for age at menarche, a milestone in female pubertal development. In Icelandic data, these signals explain ∼7.4% of the population variance in age at menarche, corresponding to ∼25% of the estimated heritability. We implicate ∼250 genes via coding variation or associated expression, demonstrating significant enrichment in neural tissues...
April 24, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28426980/hormonal-and-reproductive-risk-factors-of-papillary-thyroid-cancer-a-population-based-case-control-study-in-france
#7
Emilie Cordina-Duverger, Christophe Leux, Monica Neri, Catherine Tcheandjieu, Anne-Valérie Guizard, Claire Schvartz, Thérèse Truong, Pascal Guénel
The three times higher incidence of thyroid cancer in women compared to men points to a role of female sex hormones in its etiology. However the effects of these factors are poorly understood. We analyzed the association between thyroid cancer and hormonal and reproductive factors among women enrolled in CATHY, a population-based case-control study conducted in France. The study included 430 cases of papillary thyroid cancer and 505 controls frequency-matched on age and area of residence. The odds ratios for thyroid cancer increased with age at menarche (p trend 0...
April 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28418401/weak-associations-between-pubertal-development-and-psychiatric-and-behavioral-problems
#8
E Smith-Woolley, K Rimfeld, R Plomin
Pubertal development has been associated with adverse outcomes throughout adolescence and adulthood. However, much of the previous literature has categorized outcome variables and pubertal timing measures for ease of mean difference or odds ratio interpretation. We use a UK-representative sample of over 5000 individuals drawn from the Twins Early Development Study to extend this literature by adopting an individual differences approach and emphasizing effect sizes. We investigate a variety of psychiatric and behavioral measures collected longitudinally at ages 11, 14 and 16, for multiple raters and for males and females separately...
April 18, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28410519/in-utero-exposure-to-atrazine-analytes-and-early-menarche-in-the-avon-longitudinal-study-of-parents-and-children-cohort
#9
Gonza Namulanda, Ethel Taylor, Mildred Maisonet, Dana Boyd Barr, W Dana Flanders, David Olson, Judith R Qualters, John Vena, Kate Northstone, Luke Naeher
BACKGROUND: Evidence from experimental studies suggests that atrazine and its analytes alter the timing of puberty in laboratory animals. Such associations have not been investigated in humans. OBJECTIVE: To determine the association between in utero exposure to atrazine analytes and earlier menarche attainment in a nested case-control study of the population-based Avon Longitudinal Study of Parents and Children. METHODS: Cases were girls who reported menarche before 11...
April 11, 2017: Environmental Research
https://www.readbyqxmd.com/read/28402984/contribution-of-hormonal-cytology-in-girls-and-adolescents-to-reproductive-health-a-traditional-technique-monitoring-recent-problems
#10
Jaroslava Dušková, Barbara Goldová, Lenka Matiášková, Alena Beková, Jana Skřenková
OBJECTIVE: To study the contribution of hormonal cytology in contemporary disturbances of fertility. DESIGN: Over a 10-year period (2006-2015), 6,688 vaginal fornix cytologies of 2,350 patients were investigated. For a more detailed analysis, a 3-year period from 2013 to 2015 was chosen. Four hundred and fifty-two patients were investigated, many of them several times and for a period longer than the 3 years analyzed. RESULTS: The main disorders examined and treated via a gentle hormonal medication support and life style corrections by a pediatric gynecologist were: pubertas praecox - thelarche praecox and early menarche; dysfunctional juvenile metrorrhagia; central and peripheral endocrine disorders; eating disorders - anorexia mentalis and bulimia; obesity; excessive sport activities; autoimmune disorders, and others...
April 13, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28402199/from-menarche-to-menopause-understanding-multigenerational-reproductive-health-milestones
#11
Kimberly Field-Springer, Deleasa Randall-Griffiths, Carol Reece
Our study aims at understanding multigenerational communication among grandmothers, mothers, and daughters experiencing reproductive health transitions from menarche to menopause. Thirty women, 10 triads of grandmothers, mothers, and daughters, participated in narrative interviews to recount their menarche and menopause experiences. Analysis was read using a multilayered approach to interpret discourse positioned from self, reflexive others, and those stories informed by societal meanings. Four dialectical themes informed by generational discursive shifts in talk included (1) covert versus overt talk, (2) recollection of versus indifference to menarche, (3) bound to versus freedom from menstruation, and (4) controlling versus managing bodily changes...
April 12, 2017: Health Communication
https://www.readbyqxmd.com/read/28395581/a-case-control-study-of-rheumatoid-arthritis-revealed-abdominal-obesity-and-environmental-risk-factor-interactions-in-northern-china
#12
Lingyu Fu, Jianming Zhang, Lei Jin, Yao Zhang, Saisai Cui, Meng Chen
BACKGROUND: The aim of this study was to evaluate new and previously hypothesized environmental risk factors and their interaction with rheumatoid arthritis (RA). METHODS: Four hundred patients recently diagnosed with RA and 400 controls frequency-matched by gender and birth year using Propensity Score Matching (PSM) were selected from northern China. Investigation was performed using self-reported data from interviewer-administered surveys. Associations between exposure variables and risk of RA were evaluated using multifactor non-conditional logistic regression...
April 11, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28395463/-the-combined-effect-of-spermarche-menarche-and-obesity-on-elevated-blood-pressure-among-chinese-students
#13
Y Song, J Ma, B Zhang, P J Hu
Objective: To investigate the association between the combined effect of spermarche/menarche and obesity with elevated blood pressure among Chinese students. Methods: A total of 106 009 primary and secondary school students (55 614 boys and 50 395 girls) were selected from " 2014 National Physical Fitness and Health Surveillance" (including 31 provinces, with the exception of Hong Kong, Macao, and Taiwan) with full record of height, weight, blood pressure, puberty development data of spermarche/menarche. The level of blood pressure, as well as the prevalence of high blood pressure(HBP), were compared between different subgroups (pre-spermarche/menarche and non-obesity group, pre-spermarche/menarche and obesity group, pro-spermarche/menarche and non-obesity group, pro-spermarche/menarche and obesity group), and mulilevel logistic model was used to investigate the relationship between puberty development, obesity and blood pressure...
April 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28394509/adverse-childhood-experiences-and-risk-for-first-episode-major-depression-during-the-menopause-transition
#14
C Neill Epperson, Mary D Sammel, Tracy L Bale, Deborah R Kim, Sarah Conlin, Stephanie Scalice, Katharine Freeman, Ellen W Freeman
OBJECTIVE: Stress exposures may have a differential impact on risk and resilience for depression depending on their timing across development. We sought to determine whether adverse childhood experiences (ACEs) and their onset with respect to puberty contribute to the increased risk observed in first-episode major depressive disorder (MDD) during the menopause transition. METHODS: Participants were from the Penn Ovarian Aging Study cohort, which is composed of women from Philadelphia County, Pennsylvania, who underwent behavioral, cognitive, and endocrine evaluations approximately yearly from 1996 to 2012 and completed the Adverse Childhood Experiences Questionnaire at study end point (n = 243)...
March 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28391726/determinants-of-percent-mammographic-density-in-women-with-premature-ovarian-insufficiency
#15
F R Torelli, M F Brancalion, D A Yela, C L Benetti-Pinto
OBJECTIVE: To evaluate the determinants of breast density in women with premature ovarian insufficiency (POI). METHODS: In a cross-sectional study of 163 women with POI undergoing mammography, percent mammographic density (PMD) was evaluated by digitizing the image. PMD was correlated with age, age at menarche, age at POI, time since POI, body mass index (BMI), gestational history and hormone therapy (HT) use (duration, dose, regimen). RESULTS: POI was diagnosed at a mean age of 32...
April 9, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28391271/metabolic-outcomes-bone-health-and-risk-of-polycystic-ovary-syndrome-in-girls-with-idiopathic-central-precocious-puberty-treated-with-gonadotropin-releasing-hormone-analogues
#16
Maria Felicia Faienza, Giacomina Brunetti, Angelo Acquafredda, Maurizio Delvecchio, Antonella Lonero, Alberto Gaeta, Paola Suavo Bulzis, Domenico Corica, Maria Rosa Velletri, Filippo De Luca, Luciano Cavallo, Malgorzata Wasniewska
BACKGROUND/AIMS: Gonadotropin-releasing hormone analogues (GnRHa) represent the gold standard treatment for central precocious puberty (CPP). We aimed to assess the effects of GnRHa treatment on metabolic outcomes, bone status, and polycystic ovary syndrome (PCOS) prevalence in young girls with idiopathic CPP (ICPP). METHODS: We enrolled 94 ICPP girls who were at least 2 years after menarche and had already attained adult height at the time of the study: 56 previously treated with depot triptorelin (3...
2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28383370/dual-force-vaginoplasty-for-treatment-of-segmental-vaginal-aplasia
#17
Ali M El Saman, Mohamad A Farag, Sherif A Shazly, Mohamed Noor, Mohammed K Ali, Essam R Othman, Mansour Khalifa, Tarek A Farghly, Dina A El Saman
BACKGROUND: Vaginal aplasia occurs in 1 in 5,000-10,000 female live births. In this report, we evaluated a novel dual-force vaginoplasty technique for treatment of 11 patients with segmental vaginal aplasia. TECHNIQUE: The principle of the approach is to thin the atretic part between two counteracting forces. The instrument was inserted laparoscopically into the proximal hematocolpos. Two balloon catheters, one for drainage and one for traction, were threaded over the inserter...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28382320/female-hormonal-exposures-and-neuromyelitis-optica-symptom-onset-in-a-multicenter-study
#18
Riley Bove, Liene Elsone, Enrique Alvarez, Nadja Borisow, Melissa M Cortez, Farrah J Mateen, Maureen A Mealy, Kerry Mutch, Sean Tobyne, Klemens Ruprecht, Guy Buckle, Michael Levy, Dean M Wingerchuk, Friedemann Paul, Anne H Cross, Brian Weinshenker, Anu Jacob, Eric C Klawiter, Tanuja Chitnis
OBJECTIVE: To study the association between hormonal exposures and disease onset in a cohort of women with neuromyelitis optica spectrum disorder (NMOSD). METHODS: Reproductive history and hormone use were assessed using a standardized reproductive survey administered to women with NMOSD (82% aquaporin-4 antibody positive) at 8 clinical centers. Using multivariable regression, we examined the association between reproductive exposures and age at first symptom onset (FS)...
May 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28381475/dairy-intake-in-relation-to-breast-and-pubertal-development-in-chilean-girls
#19
Audrey J Gaskins, Ana Pereira, Daiana Quintiliano, John A Shepherd, Ricardo Uauy, Camila Corvalán, Karin B Michels
Background: Frequent dairy consumption in childhood has been related to higher growth-hormone concentrations that may affect mammary gland and pubertal development.Objective: We evaluated the relation of dairy intake to breast composition at Tanner stage 4 and age at menarche.Design: A total of 515 Chilean girls are included in the Growth and Obesity Cohort Study. The subjects have been followed longitudinally since they were 3-4 y old (from 2006 to the present). Starting in 2013, diet was assessed every 6 mo via a 24-h recall...
April 5, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28379637/change-in-postmenarche-anthropometric-indicators-in-indigenous-and-nonindigenous-adolescents-from-chile
#20
Macarena Lara, Patricia Bustos, Hugo Amigo
OBJECTIVE: To analyze the change in anthropometric indicators between menarche and 36 months after menarche among indigenous and non-indigenous adolescents from the Araucanía Region of Chile. METHOD: This was a concurrent cohort study. Of 8,504 girls interviewed, 114 indigenous adolescents and 123 nonindigenous adolescents who had recently experienced menarche were selected. Body mass index (BMI), BMI by age (BMI z-score), waist circumference (WC) and body fat percentage (BF%) were evaluated at menarche and 6, 12, 18, 24, 30, and 36 months postmenarche...
April 5, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
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