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https://www.readbyqxmd.com/read/28546440/albuminuria-proteinuria-and-renal-disease-progression-in-children-with-ckd
#1
Dana Y Fuhrman, Michael F Schneider, Katherine M Dell, Tom D Blydt-Hansen, Robert Mak, Jeffrey M Saland, Susan L Furth, Bradley A Warady, Marva M Moxey-Mims, George J Schwartz
BACKGROUND AND OBJECTIVES: The role of albuminuria as an indicator of progression has not been investigated in children with CKD in the absence of diabetes. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Children were enrolled from 49 centers of the CKD in Children study between January of 2005 and March of 2014. Cross-sectional multivariable linear regression (n=647) was used to examine the relationship between urine protein-to-creatinine (UP/C [milligrams per milligram]) and albumin-to-creatinine (ACR [milligrams per gram]) with eGFR (milliliters per minute per 1...
May 25, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28543418/reconciling-patient-safety-and-epistemic-humility-an-ethical-use-of-opioid-treatment-plans
#2
Anita Ho
In this issue of the Hastings Center Report, Joshua Rager and Peter Schwartz suggest using opioid treatment agreements as public health monitoring tools to inform patients about "the requirements entailed by undergoing opioid therapy," rather than as contractual agreements to alter patients' individual behavior or to benefit them directly. Because Rager and Schwartz's argument presents suspected OTA violations as a justification to stop providing opioids yet does not highlight the broader epistemic and systemic context within which clinicians prescribe these medications, their proposal may perpetuate a climate of distrust and stigmatization without correcting systemic factors that may have placed patients and others at risk in the first place...
May 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28543412/opioid-treatment-agreements-repurposed-but-who-monitors-the-monitors
#3
Richard Payne
In this issue of the Hastings Center Report, Joshua Rager and Peter Schwartz reframe the justification for the use of opioid treatment agreements. Instead of documents used to define the roles and responsibilities of doctors and patients to one another in the course of opioid treatment for chronic pain and to describe the risks and benefits of therapy for the individual, OTAs are now proposed for use as "surveillance and monitoring" instruments. As such, they are specifically meant to disclose the risks of opioid therapy and to describe the other processes and tools used to monitor abuse and diversion of medications...
May 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28539235/multi-institutional-evaluation-of-women-at-high-risk-of-developing-breast-cancer
#4
David J Hermel, Marie E Wood, Jennifer Chun, Tiffany Rounds, Melissa Sands, Shira Schwartz, Freya R Schnabel
INTRODUCTION: We performed the present study to better understand the practices and preferences of women with an elevated risk of breast cancer by merging the registries from 2 separate institutions and comparing the clinical characteristics and outcomes. MATERIALS AND METHODS: The data from women enrolled in institutional review board-approved registries from 2003 to 2015 at the New York University Langone Medical Center and University of Vermont Medical Center were evaluated...
April 14, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28530314/-presentation-of-ocular-problems-among-displaced-persons-from-sudan-and-eritrea-at-the-tel-aviv-medical-center
#5
Roy Schwartz, Michaella Goldstein, Anat Loewenstein, Adiel Barak
INTRODUCTION: Illegal immigration from Africa to Israel expanded in recent years, bringing illegal immigrants, mostly from Eritrea and Sudan. No data regarding the ophthalmic conditions of this population was previously published. AIMS: To delineate reasons for ophthalmologic emergency room visits and hospitalizations in the ophthalmology department at a tertiary center in Tel Aviv, Israel. METHODS: In this retrospective study we reviewed the records of patients of Eritrean and Sudanese origin arriving at the ophthalmic emergency room at the Tel Aviv Sourasky Medical Center between June 2012 and August 2012 and hospitalized in the ophthalmology ward between August 2011 and August 2012...
January 2017: Harefuah
https://www.readbyqxmd.com/read/28495651/percentile-categorization-of-qt-interval-as-an-approach-for-identifying-adult-patients-at-risk-for-cardiovascular-death
#6
Reza Mohebi, Ayesha Jehan, Aaron Grober, Victor Froelicher
BACKGROUND: The results from studies of the association of QT prolongation with CVD have been inconsistent. OBJECTIVES: To compare the major correction formulas to percentile values of QT for heart rate ranges as to their ability to remove the relationship of QT to heart rate and to predict cardiovascular death(CVD). METHODS: Participants were 16,531 veterans who had an initial ECG at the Veterans Affairs Medical Center, Palo Alto between March 31, 1987, and December 20, 1999 and were followed for CVD...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28473303/gapmap-enabling-comprehensive-autism-resource-epidemiology
#7
Nikhila Albert, Jena Daniels, Jessey Schwartz, Michael Du, Dennis P Wall
BACKGROUND: For individuals with autism spectrum disorder (ASD), finding resources can be a lengthy and difficult process. The difficulty in obtaining global, fine-grained autism epidemiological data hinders researchers from quickly and efficiently studying large-scale correlations among ASD, environmental factors, and geographical and cultural factors. OBJECTIVE: The objective of this study was to define resource load and resource availability for families affected by autism and subsequently create a platform to enable a more accurate representation of prevalence rates and resource epidemiology...
May 4, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28471976/comparative-effectiveness-of-prostate-cancer-treatments-for-patient-centered-outcomes-a-systematic-review-and-meta-analysis-prisma-compliant
#8
Ravishankar Jayadevappa, Sumedha Chhatre, Yu-Ning Wong, Marsha N Wittink, Ratna Cook, Knashawn H Morales, Neha Vapiwala, Diane K Newman, Thomas Guzzo, Alan J Wein, Stanley B Malkowicz, David I Lee, Jerome S Schwartz, Joseph J Gallo
BACKGROUND: In the context of prostate cancer (PCa) characterized by the multiple alternative treatment strategies, comparative effectiveness analysis is essential for informed decision-making. We analyzed the comparative effectiveness of PCa treatments through systematic review and meta-analysis with a focus on outcomes that matter most to newly diagnosed localized PCa patients. METHODS: We performed a systematic review of literature published in English from 1995 to October 2016...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28455620/trends-in-economic-homogamy-changes-in-assortative-mating-or-the-division-of-labor-in-marriage
#9
Pilar Gonalons-Pons, Christine R Schwartz
The growing economic resemblance of spouses has contributed to rising inequality by increasing the number of couples in which there are two high- or two low-earning partners. The dominant explanation for this trend is increased assortative mating. Previous research has primarily relied on cross-sectional data and thus has been unable to disentangle changes in assortative mating from changes in the division of spouses' paid labor-a potentially key mechanism given the dramatic rise in wives' labor supply. We use data from the Panel Study of Income Dynamics (PSID) to decompose the increase in the correlation between spouses' earnings and its contribution to inequality between 1970 and 2013 into parts due to (a) changes in assortative mating, and (b) changes in the division of paid labor...
April 28, 2017: Demography
https://www.readbyqxmd.com/read/28454604/collaboration-guidelines-between-sleep-physicians-and-dentists-in-the-management-of-obstructive-sleep-apnea-an-american-academy-of-dental-sleep-medicine-and-american-academy-of-sleep-medicine-joint-position-statement
#10
Kannan Ramar, James A Rowley, Stuart F Quan, Kathleen M Bennett, Alan Blanton, Kelly A Carden, Ronald D Chervin, Leslie Dort, Douglas B Kirsch, David A Kristo, Mitchell Levine, Raman K Malhotra, Jennifer L Martin, Eric J Olson, Kevin Postol, Ilene M Rosen, Thomas Schell, David Schwartz, Rose Sheats, Harold Smith, Nathaniel F Watson, Terri E Weaver
The boards of directors of the American Academy of Dental Sleep Medicine (AADSM) and the American Academy of Sleep Medicine (AASM) approved this position statement to provide more detailed clarification regarding the appropriate role of dentists and physicians, respectively, in the treatment and ongoing management of obstructive sleep apnea (OSA) using oral appliance therapy (OAT). In order to promote high quality, patient-centered care for patients who have chosen OAT, and to effectively and collaboratively manage these patients, dentists and sleep physicians should follow the recommendations in the updated clinical practice guideline for the treatment of OSA and snoring with OAT, which was published jointly by the AADSM and AASM in 2015...
April 25, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28452828/telephone-encounters-predict-future-high-financial-expenditures-in-inflammatory-bowel-disease-patients-a-3-year-prospective-observational-study
#11
Benjamin Click, Alyce M Anderson, Claudia Ramos Rivers, Ioannis E Koutroubakis, Jana G Hashash, Michael A Dunn, Marc Schwartz, Jason Swoger, Arthur Barrie, Eva Szigethy, Miguel Regueiro, Robert E Schoen, David G Binion
BACKGROUND: Telephone activity is essential in management of complex chronic diseases including inflammatory bowel disease (IBD). Telephone encounters logged in the electronic medical record have recently been proposed as a surrogate marker of disease activity and impending health care utilization; however, the association between telephone calls and financial expenditures has not been evaluated. STUDY: We performed a 3-year prospective observational study of telephone encounters logged at a tertiary referral IBD center...
April 27, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28451211/acyclic-quaternary-centers-from-asymmetric-conjugate-addition-of-alkylzirconium-reagents-to-linear-trisubstituted-enones
#12
Zhenbo Gao, Stephen P Fletcher
Synthetic methods for the selective formation of all carbon quaternary centres in non-cyclic systems are rare. Here we report highly enantioselective Cu-catalytic asymmetric conjugate addition of alkylzirconium species to twelve different acyclic trisubstituted enones. A variety of sp(3)-hybridized nucleophiles generated by in situ hydrozirconation of alkenes with the Schwartz reagent can be introduced, giving linear products bearing quaternary centres with up to 98% ee. The method is tolerant of several important functional groups and 27 total examples are reported...
January 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28448178/what-is-being-measured-a-comparison-of-two-depressive-symptom-severity-instruments-with-a-depression-diagnosis-in-low-income-high-risk-mothers
#13
Jenny Yang, Maria Martinez, Todd A Schwartz, Linda Beeber
BACKGROUND: Adequate assessment of depressive symptomatology is a necessary step toward decreasing income-related mental health treatment inequity. No studies have focused on comparing instruments used to detect depression in women from low-income backgrounds who are mothers of young children-a period of increased risk for depressive symptoms. METHODS: To address this gap, two commonly used instruments (Center for Epidemiologic Studies Depression Scale [CES-D] and Hamilton Rating Scale for Depression [Hamilton]) were compared with a depression diagnosis (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition [DSM-V]) in a sample (n = 251) of mothers from low-income backgrounds with children ranging from 1 to 54 months old...
April 27, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28446095/schwartz-center-rounds-can-make-staff-effective
#14
(no author information available yet)
A study into the effectiveness of Schwartz Center Rounds on healthcare staff has revealed that the programme can increase empathy for patients and improve teamwork.
April 27, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28434051/evidence-of-a-link-between-fever-and-microscopic-hematuria-in-children
#15
Rama Schwartz, Rotem Distal, Arthur Shapiro, Yehezkel Waisman
Despite the common conception that febrile illnesses are associated with microscopic hematuria in children, a review of the literature failed to disclose supportive evidence. The aim of this study was to evaluate this relationship. Background data were collected for a convenience sample of children aged 4-18 years who presented to the emergency department (ED) of a tertiary pediatric medical center. Vital signs were measured and a midstream urine specimen was collected. Specimens positive for the presence of blood (>5 erythrocytes/μl; Combur 10 Test Strips) were examined microscopically...
April 22, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28430891/development-and-validation-of-diagnostic-criteria-for-ibd-subtypes-with-an-emphasis-on-ibd-unclassified-in-children-a-multicenter-study-from-the-pediatric-ibd-porto-group-of-espghan
#16
Liron Birimberg-Schwartz, David M Zucker, Amichay Akriv, Salvatore Cucchiara, Fiona L Cameron, David C Wilson, Iza Lazowska, Lambri Yianni, Siba Prosad Paul, Claudio Romano, Sanja Kolacek, Stephan Buderus, Anders Pærregaard, Richard K Russell, Johanna C Escher, Dan Turner
Background: The revised Porto criteria identify subtypes of pediatric inflammatory bowel diseases: ulcerative colitis (UC), atypical UC, Inflammatory Bowel Disease Unclassified (IBDU), and Crohn's disease (CD). In continuation of the Porto criteria, we aimed to derive and validate criteria for standardizing the classification of the IBD subtypes. Methods: This was a multicenter retrospective longitudinal study from 23 centers affiliated with the Porto-group of ESPGHAN...
April 18, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28428725/tumor-biopsy-and-patient-enrollment-in-clinical-trials-for-advanced-hepatocellular-carcinoma
#17
Lorenza Rimassa, Maria Reig, Giovanni Abbadessa, Markus Peck-Radosavljevic, William Harris, Vittorina Zagonel, Davide Pastorelli, Elena Rota Caremoli, Camillo Porta, Nevena Damjanov, Hitendra Patel, Bruno Daniele, Maria Lamar, Brian Schwartz, Terri Goldberg, Armando Santoro, Jordi Bruix
Tumor biopsies may help to reliably distinguish hepatocellular carcinoma (HCC) from other tumors, mostly cholangiocarcinoma as well as to identify the patient populations who most benefit from target-driven HCC treatments, in order to improve the success rate of experimental therapies. Clarifying tumor biology may also lead to identify biomarkers with prognostic role and/or enabling to predict response or resistance to therapies. Recently, clinical trials have more efficiently included biomarker endpoints and increasingly collected tumor tissue from enrolled patients...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28399727/sharing-difficult-experiences-helps-everyone-to-cope-with-challenges
#18
(no author information available yet)
A study into the effectiveness of Schwartz Center Rounds on healthcare staff has revealed that the programme could increase empathy for patients and improve teamwork and communication.
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28389059/renal-response-to-a-protein-load-in-healthy-young-adults-as-determined-by-iohexol-infusion-clearance-cimetidine-inhibited-creatinine-clearance-and-cystatin-c-estimated-glomerular-filtration-rate
#19
Kyle E Rodenbach, Dana Y Fuhrman, Paula S Maier, George J Schwartz
OBJECTIVE: Renal reserve (RR) measures the increase in glomerular filtration rate (GFR) in response to a protein load; lack of RR could indicate subclinical kidney disease but such a test is not routinely used in clinical practice. The purpose of this study was to compare a meat versus liquid protein load in a cystatin C-based (Cys-C) RR test using cimetidine-inhibited creatinine clearance (Cr Cl) and iohexol infusion clearance (Io Cl) for validation. The design was cross-sectional analysis and the setting was a Clinical Research Center...
April 4, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28388976/concept-development-of-nursing-presence-application-of-schwartz-barcott-and-kim-s-hybrid-model
#20
Fatemeh Mohammadipour, Foroozan Atashzadeh-Shoorideh, Soroor Parvizy, Meimanat Hosseini
PURPOSE: Although nursing presence is a foundation for professional nursing practice and has known positive outcomes such as patient satisfaction and recovery; it is not well known. The ambiguity surrounding how to define nursing presence has challenged its evaluation and education. Therefore, in an attempt to discover attributes of this underdeveloped concept and studying it in a new context, concept development is essential. The purpose of this study was to clarify the concept of nursing presence through concept development, to produce a tentative definition of this subjective concept in clinical practice...
March 2017: Asian Nursing Research
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