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V I Shevelev, S G Kanorsky
This study was designed to compare effectiveness and safety of warfarin, direct thrombin inhibitor dabigatran, Xa factor inhibitors rivaroxaban and apixaban used to prevent stroke in 280 elderly patients in patients with age-specific non-valvular atrial fibrillation. The treatment of patients aged 65-74 and 75-80 yearsfor 2 years with dab itragan (110 mg b.i.d), apixaban (5 mg b. i. d), and rivaroxaban (20 mg once daily) prevented stroke as effectively as warfarin therapy but less frequently caused severe intracranial hemorrhage...
2015: Klinicheskaia Meditsina
O L Bockeria, A A Akhobekov, V A Shvartz, Z F Kudzoeva
BACKGROUND: The incidence of the postoperative atrialfibrillation (POAF) after open heart surgery is up to 65%. Statin therapy has shown conflicting data in the prevention of the POAF. OBJECTIVE: Our aim was eo evaluate the role of statin therapy in the primary prevention of AF after CABG. METHODS: Group 1 (n = 82) included those patients who received no statin therapy and the Group 2 (n = 124) included those patients who did receive statin therapy for at least three days prior to the operation and for all days in the postoperative period...
2015: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Komsing Methavigul, Warangkna Boonyapisit
OBJECTIVE: To determine the optimal International Normalized Ratio (INR) level in Thai atrialfibrillation (AF) patients who received warfarin. MATERIAL AND METHOD: This retrospective study enrolled 230 AF patients that received warfarin in Siriraj Hospital between January 1, 2005 andDecember 31, 2009 and collected the INR level at the time of the event, the numbers of ischemic stroke, and bleeding events. The incidence density of ischemic stroke or bleeding events was calculated by dividing the number of ischemic stroke or bleeding event in each INR level with the summation of the time that each patient stayed in each INR group...
December 2014: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Ewa Nowalany-Kozielska
Imaging studies play a very important role in the diagnosis of cardiac arrhythmias. They are able to answer many questions relating to the diagnosis and treatment of patients. Not all types of arrhythmias require you to perform imaging studies. Diagnosis require above all: ventricular tachycardia and supraventricular tachycardia, ventricular extrasystoles requiring treatment, atrialfibrillation, individuals who are at genetically diseases leading to severe arrhythmia, patients before ablation procedures and cardioversion, arrhythmias in athletes and people performing specific professions (eg pilots)...
2014: Przegla̧d Lekarski
Changsheng Ma, Xueyuan Guo
No abstract text is available yet for this article.
May 2014: Zhonghua Xin Xue Guan Bing za Zhi
Ewa Majos, Rafał Dąbrowski, Hanna Szwed
Under normal conditions function of the right ventricle (RV) is determined by the heart rhythm, RV filling time, RV systolic synchrony and interdependence between both ventricles. Failure ofthe left ventricle (LV) can lead to RV failure. Impaired function of the RV significantly worsensthe prognosis in patients after myocardial infarction and with LV failure. Permanent atrialfibrillation (AF) is one of the most common arrhythmia in patients with depressed RV function. Frequent coexistence of chronic heart failure (CHF) and AF causes overlapping of the arrhythmiaand RV dysfunction in the setting of CHF...
2013: Cardiology Journal
Andrés Ricardo Pérez Riera, Adail Paixão-Almeida, Raimundo Barbosa-Barros, Frank G Yanowitz, Adrian Baranchuk, Sergio Dubner, Antônio Carlos Palandri Chagas
Congenital or familial short QT syndrome is a genetically heterogeneous cardiac channelopathy without structural heart disease that has a dominant autosomal or sporadic pattern of transmission affecting the electric system of the heart. Patients present clinically with a spectrum of signs and symptoms including irregular palpitations due to episodes of paroxysmal atrialfibrillation, dizziness and fainting (syncope) and/or sudden cardiac death due to polymorphic ventricular tachycardia and ventricular fibrillation...
2013: Cardiology Journal
Pei De-An, Li Li, Xu Zhi-Yun, Huang Jin-Yu, Xu Zheng-Ming, Wang Min, Yao Qiang, Huang Shi-Eng
BACKGROUND: Atrialfibrillation (AF) is associated with the activation of the renin-angiotensin-aldosterone system in the atria. It is not clear whether the expression of a mineralocorticoid receptor (MR), or 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2), conferring aldosterone specificity to the MR, in patients with AF is altered. HYPOTHESIS: Patients with AF may be associated with increased expression of MR and 11betaHSD2 in the atria. METHODS: Atrial tissue samples of 25 patients with rheumatic heart valve disease undergoing a valve replacement operation were examined...
January 2010: Clinical Cardiology
Nithima Chaowalit, Decho Jakrapanichakul, Kamol Udol, Bussakorn Kitrattana
OBJECTIVE: No previous report of dobutamine stress echocardiography in the Thai population has been available. The present study seeks to document the protocol, indications, results and safety of dobutamine stress echocardiography performed at Siriraj Hospital. MATERIAL AND METHOD: The authors studied 421 [mean age 67.7 +/- 11.0 years, 179 (43%) men] consecutive Thai patients undergoing dobutamine stress echocardiography at Siriraj Hospital. The protocol, indications and echocardiographic analysis were described...
November 2007: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Marilyn Hravnak, Leslie A Hoffman, Melissa I Saul, Thomas G Zullo, Gayle R Whitman
BACKGROUND: Studies of resource utilization by patients with new-onset atrialfibrillation after coronary artery bypass grafting have addressed only length of stay and bed charges. OBJECTIVE: To compare resource utilization between patients with new-onset atrial fibrillation and patients without atrialfibrillation after isolated coronary artery bypass grafting. METHODS: Retrospective review of clinical and administrative electronic databases for 720 subjects who underwent isolated coronary artery bypass grafting with cardiopulmonary bypass in 25 months at one medical center The prevalence of atrial fibrillation was determined, and resource utilization in various hospital cost centers was compared between subjects with and without atrialfibrillation...
May 2002: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
Rob Hopfner
AstraZeneca (formerly Astra) is developing ximelagatran, an orally active thrombin inhibitor and prodrug of melagatran, for the potential prevention and treatment of venous thromboembolism (VTE) in hip and knee replacement, for prevention of stroke in atrialfibrillation (AF) and for post acute coronary syndrome. As of December 1999, the compound was undergoing phase III trials for the prevention of VTE [349551]; these were ongoing in December 2001. By December 2000, ximelagatran had entered phase III trials for the prevention of stroke in atrial fibrillation [395212]...
February 2002: Current Opinion in Investigational Drugs
Nikolaos Fragakis, Carl F Shakespeare, Guy Lloyd, Ron Simon, Julian Bostock, Phyllis Holt, Jaswinder S Gill
Patients in atrialfibrillation (AF) who fail external cardioversion are usually regarded as in permanent AF. Internal cardioversion may revert many such patients into sinus rhythm (SR) but the majority relapse rapidly into AF. We investigated whether internal cardioversion followed by biatrial pacing is an effective to restore and subsequently maintain SR in patients with permanent AF. Patients in permanent AF underwent internal cardioversion that was followed by biatrial temporary pacing for 48 hours. Those who remained in SR received a permanent biatrial pacemaker programmed to a rate responsive mode with a lower rate 90 beats/min...
March 2002: Pacing and Clinical Electrophysiology: PACE
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