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Infant <90 days

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https://www.readbyqxmd.com/read/29781955/involvements-of-parents-in-the-care-of-preterm-infants-a-pilot-study-evaluating-a-family-centered-care-intervention-in-a-chinese-neonatal-icu
#1
Rong Zhang, Rui-Wena Huang, Xi-Ronga Gao, Xiao-Minga Peng, Li-Hui Zhu, Ramanathan Rangasamy, Jos M Latour
OBJECTIVES: To evaluate the effectiveness and safety of a family-centered care intervention in a Chinese neonatal ICU. DESIGN: Pilot study using a randomized controlled trial design to inform a main randomized controlled trial study. SETTING: Stand-alone tertiary children's hospital in China with a 60-bed neonatal ICU serving as a regional neonatal ICU center. PATIENTS: Premature infants (n = 61) and their parents (n = 110)...
May 17, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29777276/prophylactic-placement-of-internal-iliac-balloons-in-patients-with-abnormal-placental-implantation-maternal-and-foetal-outcomes
#2
Patrick J Nicholson, Owen O'Connor, John Buckley, Liam D Spence, Richard A Greene, David J Tuite
PURPOSE: To report on outcomes following the use of prophylactic internal iliac artery occlusion balloons in patients with abnormal placental implantation. METHODS: A retrospective analysis was undertaken of patients with abnormal placental implantation who underwent prophylactic iliac balloon placement prior to delivery in a University Maternity Hospital. Various clinical and technical factors were analysed, including technical success of balloon placement, blood loss and number of blood units transfused, duration of surgery, length of stay, hysterectomy rates, complications related to the balloon insertion, foetal pH and infant Apgar scores...
May 18, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29775548/open-versus-laparoscopic-approach-for-morgagni-s-hernia-in-infants-and-children-a-systematic-review-and-meta-analysis
#3
Giuseppe Lauriti, Elke Zani-Ruttenstock, Vincenzo D Catania, Lina Antounians, Pierluigi Lelli Chiesa, Agostino Pierro, Augusto Zani
INTRODUCTION: The laparoscopic repair of Morgagni's hernia (MH) has been reported to be safe and feasible. However, it is still unclear whether laparoscopy is superior to open surgery in repairing MH. MATERIALS AND METHODS: Using a defined search strategy, three investigators independently identified all comparative studies reporting data on open and laparoscopic MH repair in patients <18 years of age. Case reports and opinion articles were excluded. Meta-analysis was conducted according to PRISMA guidelines and using RevMan 5...
May 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29760843/multicenter-study-of-albuterol-use-among-infants-hospitalized-with-bronchiolitis
#4
Anna Condella, Jonathan M Mansbach, Kohei Hasegawa, Peter S Dayan, Ashley F Sullivan, Janice A Espinola, Carlos A Camargo
Introduction: Although bronchiolitis is a common reason for infant hospitalization, significant heterogeneity persists in its management. The American Academy of Pediatrics currently recommends that inhaled albuterol not be used in routine care of children with bronchiolitis. Our objective was to identify factors associated with pre-admission (e.g., emergency department or primary care) use of albuterol among infants hospitalized for bronchiolitis. Methods: We analyzed data from a 17-center observational study of 1,016 infants (age <1 year) hospitalized with bronchiolitis between 2011-2014...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29756159/survival-and-associated-risk-factors-for-mortality-among-infants-with-critical-congenital-heart-disease-in-a-developing-country
#5
Mohd Nizam Mat Bah, Mohd Hanafi Sapian, Mohammad Tamim Jamil, Amelia Alias, Norazah Zahari
Critical congenital heart disease (CCHD) is associated with significant morbidity and mortality. However, data on survival of CCHD and the risk factors associated with its mortality are limited. This study examined CCHD survival and the risk factors for CCHD mortality. Using a retrospective cohort study of infants born with CCHD from 2006 to 2015, survival over 10 years was estimated using Kaplan-Meier analysis, and the risk factors for mortality were analyzed using multivariate Cox proportional hazards regression...
May 14, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29746301/effect-of-point-of-care-early-infant-diagnosis-on-antiretroviral-therapy-initiation-and-retention-of-patients-a-cluster-randomised-trial
#6
Ilesh V Jani, Bindiya Meggi, Osvaldo Loquiha, Ocean Tobaiwa, Chishamiso Mudenyanga, Alcina Zitha, Dadirayi Mutsaka, Nedio Mabunda, Adolfo Vubil, Timothy Bollinger, Lara Vojnov, Trevor F Peter
OBJECTIVE: We measured the effect of point-of-care early infant HIV testing on antiretroviral therapy initiation rates and retention in care among infants in Mozambique. DESIGN: A cluster-randomised trial was conducted in 16 primary health care centres providing either on-site point-of-care (POC arm; n = 8) or referred laboratory (SOC arm; n = 8) infant HIV testing. METHODS: The primary outcomes were the proportion of HIV-positive infants initiating antiretroviral therapy within 60 days of sample collection, and the proportion of HIV-positive infants who initiated antiretroviral therapy that were retained in care at 90 days of follow-up...
May 8, 2018: AIDS
https://www.readbyqxmd.com/read/29739998/infants-dietary-arsenic-exposure-during-transition-to-solid-food
#7
Antonio J Signes-Pastor, Kathryn L Cottingham, Manus Carey, Vicki Sayarath, Thomas Palys, Andrew A Meharg, Carol L Folt, Margaret R Karagas
Early-life exposure to inorganic arsenic (i-As) may cause long-lasting health effects, but as yet, little is known about exposure among weaning infants. We assessed exposure before and during weaning and investigated the association between solid food intake and infants' urinary arsenic species concentrations. Following the recording of a comprehensive 3 day food diary, paired urine samples (pre- and post-weaning) were collected and analyzed for arsenic speciation from 15 infants participating in the New Hampshire Birth Cohort Study...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29694825/birth-outcomes-for-pregnant-women-with-hiv-using-tenofovir-emtricitabine
#8
COMPARATIVE STUDY
Kathryn Rough, George R Seage, Paige L Williams, Sonia Hernandez-Diaz, Yanling Huo, Ellen G Chadwick, Judith S Currier, Risa M Hoffman, Emily Barr, David E Shapiro, Kunjal Patel
BACKGROUND: In a previous trial of antiretroviral therapy (ART) involving pregnant women with human immunodeficiency virus (HIV) infection, those randomly assigned to receive tenofovir, emtricitabine, and ritonavir-boosted lopinavir (TDF-FTC-LPV/r) had infants at greater risk for very premature birth and death within 14 days after delivery than those assigned to receive zidovudine, lamivudine, and ritonavir-boosted lopinavir (ZDV-3TC-LPV/r). METHODS: Using data from two U...
April 26, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29691835/rufinamide-add-on-therapy-for-refractory-epilepsy
#9
REVIEW
Mariangela Panebianco, Hemanshu Prabhakar, Anthony G Marson
BACKGROUND: Epilepsy is a central nervous system disorder (neurological disorder). Epileptic seizures are the result of excessive and abnormal cortical nerve cell electrical activity in the brain. Despite the development of more than 10 new antiepileptic drugs (AEDs) since the early 2000s, approximately a third of people with epilepsy remain resistant to pharmacotherapy, often requiring treatment with a combination of AEDs. In this review, we summarised the current evidence regarding rufinamide, a novel anticonvulsant medication, which, as a triazole derivative, is structurally unrelated to any other currently used anticonvulsant medication, when used as an add-on treatment for refractory epilepsy...
April 25, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29680409/-usefulness-of-early-lung-ultrasound-in-acute-mild-moderate-acute-bronchiolitis-a-pilot-study
#10
Elia Zoido Garrote, Cristina García Aparicio, Constanza Camila Torrez Villarroel, Antonio Pedro Vega García, Manoel Muñiz Fontán, Ignacio Oulego Erroz
OBJECTIVE: To determine the correlation between the findings seen in early lung ultrasound with the clinical severity scales, and its association with the subsequent progression of the mild-moderate acute bronchiolitis (AB). PATIENTS AND METHODS: An observational prospective study conducted on infants with mild-moderate BA, using lung ultrasound in the first 24hours of hospital care. The lung involvement was graded (range 0-50 points) based on an ultrasound score (ScECO) and 2routinely used clinical scales: the modified Wood Downes Ferres (WDFM), and the Hospital Sant Joan de Deu (HSJD)...
April 18, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29678229/the-use-of-serological-tests-in-combination-with-the-intradermal-tuberculin-test-maximizes-the-detection-of-tuberculosis-infected-goats
#11
Javier Bezos, Álvaro Roy, José Antonio Infantes-Lorenzo, Isabel González, Ángel Venteo, Beatriz Romero, Anna Grau, Olga Mínguez, Lucas Domínguez, Lucía de Juan
The diagnosis of tuberculosis (TB) in goats is based mainly on the single and comparative intradermal tuberculin (SIT and CIT) tests and, exceptionally, on the interferon-gamma (IFN-γ) assay, however they are not perfect in terms of sensitivity and specificity. Nevertheless, various serological assays that provide a potential cost-effective approach for the control of TB are also available or under development, and a variety of results have been reported regarding the ability of these tests to detect infected animals, particularly in the early stages of infection...
May 2018: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/29660295/breastfeeding-twins-factors-related-to-weaning
#12
Fernanda Cristina Ferreira Mikami, Rossana Pulcineli Vieira Francisco, Agatha Rodrigues, Wagner Rodrigues Hernandez, Marcelo Zugaib, Maria de Lourdes Brizot
BACKGROUND: Many factors may influence a woman's decision to start and maintain breastfeeding. Research aim: This study aimed to investigate the factors associated with breastfeeding cessation in twin infants during the first 6 months after birth and to describe the main reasons for weaning cited by mothers of twins. METHODS: This is a secondary data analysis of a prospective randomized trial conducted in Brazil. Data were obtained through longitudinal quantitative and qualitative self-reported interviews...
April 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29627993/the-diagnostic-dilemma-of-traumatic-lumbar-puncture-current-standing-of-cerebrospinal-fluid-leukocyte-corrections-and-our-experience-with-cerebrospinal-fluid-biomarkers
#13
Mudasir Nazir, Wasim Ahmad Wani, Khalid Kawoosa, Sheeraz Ahmad Dar, Muzaffar Malik, Naseer Yousuf Mir, Ikhlas Ahmad, Rais Ahmad Bhat, Javeed Iqbal Bhat, Qazi Iqbal Ahmad, Bashir Ahmad Charoo, Syed Wajid Ali
OBJECTIVE: To assess the diagnostic efficiency of cerebrospinal fluid markers of procalcitonin, lactate, and cerebrospinal fluid/serum lactate ratio for detecting bacterial meningitis during traumatic lumbar puncture, and to compare these markers with routinely used uncorrected and corrected leukocyte measurements. METHODS: Infants aged ≤90 days with traumatic lumbar puncture were prospectively studied. The diagnostic characteristics of cerebrospinal fluid assays of uncorrected and corrected leukocyte count, procalcitonin, lactate, and lactate ratio were described and compared...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29620706/furosemide-response-predicts-acute-kidney-injury-after-cardiac-surgery-in-infants-and-neonates
#14
Santiago Borasino, Kevin M Wall, Jack H Crawford, Kristal M Hock, David C Cleveland, Fazlur Rahman, Kimberly D Martin, Jeffrey A Alten
OBJECTIVE: Cardiac surgery-induced acute kidney injury occurs frequently in neonates and infants and is associated with postoperative morbidity/mortality; early identification of cardiac surgery-induced acute kidney injury may be crucial to mitigate postoperative morbidity. We sought to determine if hourly or 6-hour cumulative urine output after furosemide in the first 24 hours after cardiopulmonary bypass could predict development of cardiac surgery-induced acute kidney injury and other deleterious outcomes...
April 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29601801/the-accuracy-of-transcutaneous-bilirubinometer-measurements-to-identify-the-hyperbilirubinemia-in-outpatient-newborn-population
#15
Şerif Ercan, Günay Özgün
OBJECTIVES: To assess the ability of transcutaneous bilirubinometer for prediction total serum bilirubin levels in newborn infants after hospital discharge. METHODS: Newborn infants requiring total serum bilirubin (TSB) level measurement during an outpatient follow-up visit were included into the study. Transcutaneous bilirubin (TcB) measurement was carried out using JH20-1C (Ningbo David, China) transcutaneous jaundice detector and total serum bilirubin was simultaneously determined by direct spectrophotometry...
March 27, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29582144/peritoneal-drainage-in-pneumoperitoneum-in-extremely-low-birth-weight-infants
#16
Ilse Broekaert, Titus Keller, Daisy Schulten, Christoph Hünseler, Angela Kribs, Martin Dübbers
The aim was to determine if peritoneal drainage (PD) is a suitable treatment for pneumoperitoneum in extremely low birth weight (ELBW) infants. A retrospective chart review of 42 ELBW infants with pneumoperitoneum at the University Hospital of Cologne between November 2014 and April 2017 was performed. Forty-two infants with a median birth weight of 645 g (interquartile range (IQR) 550, 806) and a median gestational age of 24.3 weeks (IQR 23.2, 25.6) were treated for pneumoperitoneum. Twenty-six (62%) received PD, and in ten (38%), the drain could be removed without further intervention...
March 26, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29565956/neonatal-sleep-restriction-increases-nociceptive-sensitivity-in-adolescent-mice
#17
Paula Araujo, Cesar A Coelho, Maria G Oliveira, Sergio Tufik, Monica L Andersen
BACKGROUND: Sleep loss in infants may have a negative effect on the functional and structural development of the nociceptive system. We tested the hypothesis that neonatal sleep restriction induces a long-term increase of pain-related behaviors in mice and that this hypersensitivity occurs due to changes in the neuronal activity of nociceptive pathways. OBJECTIVES: We aim to investigate the effects of sleep loss in neonatal mice on pain behaviors of adolescent and adult mice in a sex-dependent manner...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29557610/vitamin-a-content-in-mature-breast-milk-and-its-adequacy-to-the-nutritional-recommendations-for-infants
#18
Natalia Matamoros, Silvana Visentin, Guillermina Ferrari, Mariana Falivene, Victoria Fasano, Horacio F González
OBJECTIVE: To determine vitamin A content in breast milk and evaluate whether it satisfies the recommendations for infants. MATERIAL AND METHODS: Observational, prospective, cross sectional study. Milk samples were obtained between 30 and 90 days postpartum from mothers seen in public hospitals, and analyzed. Vitamin A concentration was determined by chromatography and its adequacy to the recommended dietary intake. The correlation between outcome measures was analyzed using Spearman's correlation coefficient...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29520678/intraoperative-feasibility-of-bulbocavernosus-reflex-monitoring-during-untethering-surgery-in-infants-and-children
#19
Takeaki Shinjo, Hironobu Hayashi, Tsunenori Takatani, Eishu Boku, Hiroyuki Nakase, Masahiko Kawaguchi
Bulbocavernosus reflex (BCR) monitoring is used to assess the integrity of urinary and bowel function. In this study, we evaluated the feasibility of BCR monitoring during untethering surgery in infants and children to predict postoperative urinary and bowel dysfunction. The records of 22 patients ranging from 4 days to 10 years old (mean 2.7 ± 3.3 years) were reviewed. Anesthesia was maintained by propofol or sevoflurane/opioid without neuromuscular blockade. BCR waveforms induced by electrical stimulation (20-40 mA, train-of-four pulses with 500 Hz) to the penis or clitoris were recorded from bilateral external anal sphincters...
March 8, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29516585/utilization-of-drugs-with-pregnancy-exposure-registries-during-pregnancy
#20
Onyekachukwu A Illoh, Sengwee Toh, Susan E Andrade, Christian Hampp, Leyla Sahin, Kate Gelperin, Lockwood Taylor, Steven T Bird
PURPOSE: To describe the utilization of drugs with pregnancy exposure registries by trimester during pregnancy, in comparison with matched nonpregnant episodes and a pre-pregnancy period. METHODS: We identified live-born deliveries from women aged 10 to 54 years and matched the pregnancies 1:1 with nonpregnant episodes from a comparator cohort not delivering live-born infants, using data from 2001 to 2013 in the Sentinel Distributed Database. We evaluated the utilization of 34 drugs with pregnancy exposure registries, comparing utilization during pregnancy to the matched nonpregnant episodes, and to the 90 days before pregnancy...
March 8, 2018: Pharmacoepidemiology and Drug Safety
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