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https://www.readbyqxmd.com/read/28220684/living-donor-liver-transplantation-during-the-first-three-months-of-life
#1
Mureo Kasahara, Seisuke Sakamoto, Kengo Sasaki, Hajime Uchida, Toshihiro Kitajima, Takanobu Shigeta, Soichi Narumoto, Yoshihiro Hirata, Akinari Fukuda
BACKGROUND: Living donor liver transplantation is now an established technique for treating children with end-stage liver disease. Few data exist about liver transplantation for exclusively young infants, especially infants of <3 months of age. We report our single-center experience with 12 cases in which living donor liver transplantation (LT) was performed during the first 3 months of life and compare the results with those of older infants who underwent LT. All of the patients were treated at the National Center of Child Health and Development, Tokyo, Japan...
February 21, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28201824/evidence-of-early-pulmonary-hypertension-is-associated-with-increased-mortality-in-very-low-birth-weight-infants
#2
Andrew Berenz, Jeffrey E Vergales, Jonathan R Swanson, Robert A Sinkin
Objective The objective of this study was to describe the inhospital outcomes of a high-risk cohort of very low birth weight infants with evidence of pulmonary hypertension (PHT) within the first 2 weeks after delivery. Design A retrospective cohort study of consecutively admitted neonates with birth weight < 1,500 g admitted to a Level IV neonatal intensive care unit who were evaluated by echocardiogram between 72 hours and 14 days. Results A total of 343 eligible infants were included in the cohort with a median gestational age of 25...
February 15, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28196932/a-clinical-prediction-rule-for-rebound-hyperbilirubinemia-following-inpatient-phototherapy
#3
Pearl W Chang, Michael W Kuzniewicz, Charles E McCulloch, Thomas B Newman
OBJECTIVES: The American Academy of Pediatrics provides little guidance on when to discontinue phototherapy in newborns treated for hyperbilirubinemia. We sought to develop a prediction rule to estimate the probability of rebound hyperbilirubinemia after inpatient phototherapy. METHODS: Subjects for this retrospective cohort study were infants born in 2012 to 2014 at ≥35 weeks' gestation at 16 Kaiser Permanente Northern California hospitals who received inpatient phototherapy before age 14 days...
February 14, 2017: Pediatrics
https://www.readbyqxmd.com/read/28194694/thyroid-status-of-iodine-deficient-newborn-infants-living-in-central-region-of-turkey-a-pilot-study
#4
Osman Bastug, Levent Korkmaz, Hulya Halis, Seyma Memur, Sabriye Korkut, Ahmet Ozdemir, Tamer Gunes, Mehmet Adnan Ozturk, Selim Kurtoglu
BACKGROUND: Iodine deficiency (ID) during the fetal and neonatal periods can lead to neonatal hypothyroidism. This study was conducted to evaluate the effect of ID on the thyroid hormone level of newborns living in Turkey. METHODS: Between 1998 and 2013, 71 newborns with a urinary iodine concentration <100 μg/L were recruited into the study. Data on thyroid volume, free triiodothyronine (fT3), free thyroxine (fT4), thyroid stimulating hormone (TSH), and thyroglobulin (Tg) were collected from all newborns, and on breast milk iodine from their mothers...
February 14, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28176333/selective-versus-routine-use-of-episiotomy-for-vaginal-birth
#5
REVIEW
Hong Jiang, Xu Qian, Guillermo Carroli, Paul Garner
BACKGROUND: Some clinicians believe that routine episiotomy, a surgical cut of the vagina and perineum, will prevent serious tears during childbirth. On the other hand, an episiotomy guarantees perineal trauma and sutures. OBJECTIVES: To assess the effects on mother and baby of a policy of selective episiotomy ('only if needed') compared with a policy of routine episiotomy ('part of routine management') for vaginal births. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register (14 September 2016) and reference lists of retrieved studies...
February 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28164936/the-effects-of-acoustic-white-noise-on-the-rat-central-auditory-system-during-the-fetal-and-critical-neonatal-periods-a-stereological-study
#6
Mohammad Saied Salehi, Mohammad Reza Namavar, Amin Tamadon, Raziyeh Bahmani, Mohammad Reza Jafarzadeh Shirazi, Homayoun Khazali, Leila Dargahi, Sareh Pandamooz, Farzad Mohammad-Rezazadeh, Fatemeh Sadat Rashidi
AIM: To evaluate the effects of long-term, moderate level noise exposure during crucial periods of rat infants on stereological parameters of medial geniculate body (MGB) and auditory cortex. MATERIALS AND METHODS: Twenty-four male offspring of 12 pregnant rats were divided into four groups: fetal-to-critical period group, which were exposed to noise from the last 10 days of fetal life till postnatal day (PND) 29; fetal period group that exposed to noise during the last 10 days of fetal life; critical period group, exposed to noise from PND 15 till PND 29, and control group...
January 2017: Noise & Health
https://www.readbyqxmd.com/read/28122520/postnatal-depression-screening-in-a-paediatric-primary-care-setting-in-italy
#7
Antonio Clavenna, Elena Seletti, Massimo Cartabia, Anna Didoni, Filomena Fortinguerra, Teresa Sciascia, Luca Brivio, Daniela Malnis, Maurizio Bonati
BACKGROUND: Postnatal depression is a non-psychotic depressive disorder that begins within 4 weeks of childbirth and occurs in 13% of mothers and 10% of fathers. A prospective study with the aim to evaluate the prevalence of postnatal depression by screening parents with the Edinburgh Postnatal Depression Scale (EPDS) in the Italian paediatric primary care setting was performed. METHODS: Mothers and fathers of infants born between 1 February and 31 July 2012, living in Italy's Milan-1 local health unit area, represented the target population of this pilot study...
January 25, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28121832/central-venous-to-arterial-co2-difference-after-cardiac-surgery-in-infants-and-neonates
#8
Leslie A Rhodes, W Clinton Erwin, Santiago Borasino, David C Cleveland, Jeffrey A Alten
OBJECTIVES: Venous to arterial CO2 difference correlates with cardiac output in critically ill adults, but its utility in pediatric patients is unclear. We sought to correlate venous to arterial CO2 difference with other cardiac output surrogates (arteriovenous oxygen saturation difference, central venous oxygen saturation, and lactate) and investigate its capacity to predict poor outcomes associated with low cardiac output (low cardiac output syndrome) in infants after cardiac surgery with cardiopulmonary bypass...
January 24, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28119425/outcomes-from-a-hearing-targeted-cytomegalovirus-screening-program
#9
Marissa L Diener, Cathleen D Zick, Stephanie Browning McVicar, Jill Boettger, Albert H Park
BACKGROUND AND OBJECTIVES: Cytomegalovirus (CMV) is the most common congenital infection and nongenetic cause of congenital sensorineural hearing loss in the United States. Utah was the first state to pass legislation mandating CMV screening for newborns who fail newborn hearing screening (NBHS). The study objective was to present outcomes of hearing-targeted CMV screening and determine factors predicting CMV screening. METHODS: We used Utah Department of Health HiTrack and Vital Records databases to examine CMV screening from 509 infants who failed NBHS in the 24 months after implementation of the Utah legislation...
January 24, 2017: Pediatrics
https://www.readbyqxmd.com/read/28118300/early-application-of-the-ponseti-casting-technique-for-clubfoot-correction-in-sick-infants-at-the-neonatal-intensive-care-unit
#10
Ehud Lebel, Eliraz Weinberg, Tamar M Berenstein-Weyel, Ruben Bromiker
The treatment of congenital clubfoot has been changing rapidly since the mid-1990s with the worldwide use of the Ponseti method for serial casting and limited operative interventions. This method was first applied for isolated clubfeet and later on for other types of clubfoot (teratologic, residual, and neurogenic). Premature babies sustaining clubfoot commonly suffer from additional congenital and acquired medical problems. These may postpone clubfoot management until urgent issues are resolved. The current study describes early initiation of treatment of clubfoot in premature babies at the neonatal intensive care unit (NICU) and their outcomes...
March 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28107101/enhancing-human-milk-production-with-domperidone-in-mothers-of-preterm-infants
#11
Elizabeth V Asztalos, Marsha Campbell-Yeo, Orlando P da Silva, Shinya Ito, Alex Kiss, David Knoppert
BACKGROUND: Mothers of preterm infants often are at risk of expressing an inadequate amount of milk for their infants and the use of galactogogues is often considered. Domperidone is a widely used galactogogue with little information available to guide clinicians regarding initiation, timing, and duration of treatment. Research aim: The primary objective of this study was to determine whether administration of domperidone within the first 21 days after delivery would lead to a higher proportion of mothers achieving a 50% increase in the volume of milk at the end of 14 days of treatment compared with mothers receiving placebo...
February 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28089641/current-outcomes-of-one-stage-surgical-correction-for-berry-syndrome
#12
Renjie Hu, Wen Zhang, Xinrong Liu, Wei Dong, Hongbin Zhu, Haibo Zhang
OBJECTIVES: Berry syndrome is a combination of distal aortopulmonary window (APW), aortic origin of the right pulmonary artery (RPA), intact ventricular septum, and interrupted aortic arch. We present here our current experience of primary repair of this syndrome with the goal of optimizing treatment for this rare condition. METHODS: From January 2003 through December 2015, 16 infants with Berry syndrome underwent one-stage repair at Shanghai Children's Medical Center...
December 19, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28063805/effect-of-prenatal-counseling-on-breastfeeding-rates-in-mothers-of%C3%A2-twins
#13
Fernanda Cristina Ferreira Mikami, Maria de Lourdes Brizot, Terezinha Hideco Tase, Elizabeth Saccuman, Rossana Pulcineli Vieira Francisco, Marcelo Zugaib
OBJECTIVE: To investigate the effect of antenatal breastfeeding counseling on the breastfeeding rates for women who give birth to twins. DESIGN: Prospective randomized trial. SETTING: Multiple Pregnancy Unit, Obstetrics Department, University of São Paulo, Brazil. PARTICIPANTS: A total of 171 mothers of twins and their 342 infants. METHODS: The participants were randomized into the prenatal counseling group (PCG) or control group (CG)...
January 5, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28060524/association-between-gestational-weight-gain-and-delayed-onset-of-lactation-the-moderating-effects-of-race-ethnicity
#14
Zelalem T Haile, Bhakti Bhaoo Chavan, Asli Teweldeberhan, Ilana R Chertok
BACKGROUND: In the United States, a high percentage of pregnant women gain weight outside of the current Institute of Medicine's (IOM) gestational weight gain (GWG) recommendations. There is limited research examining the relationship between GWG and onset of lactation. Delayed onset of lactation (DOL) can negatively affect breastfeeding outcomes. METHODS: Secondary data analysis was conducted using data from 2,053 women who participated in the population-based Infant Feeding Practices Study II between 2005 and 2007...
January 6, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28031546/sunlight-exposure-and-vitamin-d-status-in-breastfed-infants
#15
Pinky Meena, Aashima Dabas, Dheeraj Shah, Rajeev Kumar Malhotra, S V Madhu, Piyush Gupta
OBJECTIVE: To correlate the sunlight exposure in first 6 months to vitamin D status at 6 months of age in predominantly breastfed infants; and to quantify the sunlight exposure required to achieve serum 25(OH)D level > 20 ng/mL, by 6 months of age. DESIGN: Prospective cohort. SETTING: Tertiary care hospital predominantly catering to urban poor population in Delhi. PARTICIPANTS: 132 healthy infants, delivered at term, and predominantly breastfed were enrolled at 6-8 weeks of age...
December 5, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27990350/supporting-parents-of-premature-infants-transitioning-from-the-nicu-to-home-a-pilot-randomized-control-trial-of-a-smartphone-application
#16
Craig F Garfield, Young Seok Lee, Hyung Nam Kim, Joshua Rutsohn, Janine Yasmin Kahn, Brian Mustanski, David C Mohr
OBJECTIVE: To determine whether parents of Very Low Birth Weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU) transitioning home with the NICU-2-Home smartphone application have greater parenting self-efficacy, are better prepared for discharge and have shorter length of stay (LOS) than control parents. METHODS: A four-week pilot randomized controlled trial during the transition home with 90 VLBW parents randomized to usual care (n=44) or usual care plus NICU-2-Home (n=46), a smartphone application designed for VLBW parents...
May 2016: Internet Interventions: the Application of Information Technology in Mental and Behavioural Health
https://www.readbyqxmd.com/read/27988146/simplified-antibiotic-regimens-for-treatment-of-clinical-severe-infection-in-the-outpatient-setting-when-referral-is-not-possible-for-young-infants-in-pakistan-simplified-antibiotic-therapy-trial-satt-a-randomised-open-label-equivalence-trial
#17
Fatima Mir, Imran Nisar, Shiyam S Tikmani, Benazir Baloch, Sadia Shakoor, Fyezah Jehan, Imran Ahmed, Simon Cousens, Anita K M Zaidi
BACKGROUND: Parenteral antibiotic therapy for young infants (aged 0-59 days) with suspected sepsis is sometimes not available or feasible in countries with high neonatal mortality. Outpatient treatment could save lives in such settings. We aimed to assess the equivalence of two simplified antibiotic regimens, comprising fewer injections and oral rather than parenteral administration, compared with a reference treatment for young infants with clinical severe infection. METHODS: We undertook the Simplified Antibiotic Therapy Trial (SATT), a three-arm, randomised, open-label, equivalence trial in five communities in Karachi, Pakistan...
February 2017: Lancet Global Health
https://www.readbyqxmd.com/read/27987368/postnatal-systemic-inflammation-and-neuro-ophthalmologic-dysfunctions-in-extremely-low-gestational-age-children
#18
Mari Holm, Dordi Austeng, Raina N Fichorova, Elizabeth N Allred, Karl C Kuban, T Michael O'Shea, Olaf Dammann, Alan Leviton
AIM: Compared to infants born at term, children born very preterm are at increased risk of visual dysfunctions and neonatal systemic inflammation. Here, we explore whether these two propensities are related. METHODS: As part of the ELGAN study, the concentrations of 16 mediators of inflammation were measured in blood obtained on postnatal days 1, 7, 14, 21 and 28 from 1062 children born before the 28th week of gestation. Presence of visual field deficit, strabismus and/or impaired visual fixation was recorded at age two...
March 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/27940667/management-and-outcomes-of-previously-healthy-full-term-febrile-infants-ages-7-to-90-days
#19
Tara L Greenhow, Yun-Yi Hung, Robert H Pantell
BACKGROUND: There is considerable variation in the approach to infants presenting to the emergency department and outpatient clinics with fever without a source. We set out to describe the current clinical practice regarding culture acquisition on febrile young infants and review the outcomes of infants with and without cultures obtained. METHODS: This study analyzed Kaiser Permanente Northern California's electronic medical record to identify all febrile, full term, previously healthy infants born between July 1, 2010, and June 30, 2013, presenting for care between 7 and 90 days of age...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27923247/patterns-of-empiric-antibiotic-administration-for-presumed-early-onset-neonatal-sepsis-in-neonatal-intensive-care-units-in-the-united-states
#20
Emily A Oliver, Patricia B Reagan, Jonathan L Slaughter, Catalin S Buhimschi, Irina A Buhimschi
Objective To evaluate current patterns in empiric antibiotic use for early-onset neonatal sepsis (EONS). Study Design Retrospective population-based cohort study of newborns admitted on postnatal day 0 to 1 and discharged from NICUs participating in the Pediatric Health Information System (PHIS 2006-2013). Analyses included frequency of antibiotic initiation within 3 days of birth, duration of first course, and variation among hospitals. Results Of 158,907 newborns, 118,624 (74.7%) received antibiotics on or before postnatal day 3...
December 6, 2016: American Journal of Perinatology
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