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https://www.readbyqxmd.com/read/28625190/association-between-early-echocardiography-therapy-for-patent-ductus-arteriosus-and-outcomes-in-very-low-birth-weight-infants
#1
Jan Hau Lee, Rachel G Greenberg, Bin H Quek, Reese H Clark, Matthew M Laughon, P Brian Smith, Christoph P Hornik
BACKGROUND: In very low birth weight infants, persistence of a patent ductus arteriosus results in morbidity and mortality. Therapies to close the ductus are effective, but clinical outcomes may depend on the accuracy of diagnosis and the timing of administration. The objective of the present study was to characterise the association between early echocardiography, therapy for patent ductus arteriosus, and outcomes in very low birth weight infants. METHODS: This retrospective cohort study used electronic health record data on inborn infants of gestational age ⩽28 weeks and birth weight <1500 g who were discharged after day of life 7 from 362 neonatal ICU from 1997 to 2013...
June 19, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28621890/reference-data-for-babybody-plethysmographic-measurements-in-chinese-neonates-and-infants
#2
Gaoli Jiang, Albert Li, Libo Wang, Liling Qian, Yun Cao, Jianfeng Huang, Chengzhou Wan, Xiaobo Zhang
BACKGROUND AND OBJECTIVE: Population-specific pulmonary function reference data are essential to identify the nature and severity of respiratory diseases. However, there is a lack of reference data for Chinese neonates and infants. The objective of this study was to develop reference data for tidal breathing and plethysmographic measurements for Chinese subjects during the first 2 years of life. METHODS: Data of tidal breathing and plethysmography from healthy Chinese neonates (≤28 days) and infants (1-24 months) using the Jaeger MasterScreen BabyBody were collated...
June 16, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28614956/interventions-for-treating-hyperemesis-gravidarum-a-cochrane-systematic-review-and-meta-analysis
#3
Rupsa C Boelig, Samantha J Barton, Gabriele Saccone, Anthony J Kelly, Steven J Edwards, Vincenzo Berghella
INTRODUCTION: While nausea and vomiting in early pregnancy are very common, affecting approximately 80% of pregnancies, hyperemesis gravidarum is a severe form affecting 0.3-1.0% of pregnancies. Although hyperemesis gravidarum is rarely a source of mortality, it is a significant source of morbidity. It is one of the most common indications for hospitalization in pregnancy. Beyond the maternal and fetal consequences of malnutrition, the severity of hyperemesis symptoms causes a major psychosocial burden leading to depression, anxiety, and even pregnancy termination...
June 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28600447/the-epidemiology-management-and-outcomes-of-bacterial-meningitis-in-infants
#4
Lynda Ouchenir, Christian Renaud, Sarah Khan, Ari Bitnun, Andree-Anne Boisvert, Jane McDonald, Jennifer Bowes, Jason Brophy, Michelle Barton, Joseph Ting, Ashley Roberts, Michael Hawkes, Joan L Robinson
OBJECTIVES: The pathogens that cause bacterial meningitis in infants and their antimicrobial susceptibilities may have changed in this era of increasing antimicrobial resistance, use of conjugated vaccines, and maternal antibiotic prophylaxis for group B Streptococcus (GBS). The objective was to determine the optimal empirical antibiotics for bacterial meningitis in early infancy. METHODS: This was a cohort study of infants <90 days of age with bacterial meningitis at 7 pediatric tertiary care hospitals across Canada in 2013 and 2014...
June 9, 2017: Pediatrics
https://www.readbyqxmd.com/read/28598324/a-case-control-study-to-assess-the-effectiveness-of-pertussis-vaccination-during-pregnancy-on-newborns-valencian-community-spain-1-march-2015-to-29-february-2016
#5
Juan Bellido-Blasco, Silvia Guiral-Rodrigo, Ana Míguez-Santiyán, Antonio Salazar-Cifre, Francisco González-Morán
In the Valencian Community (Spain), the programme of maternal pertussis vaccination during pregnancy started in January 2015. The objective of this study was to estimate in this region the vaccine effectiveness (VE) in protecting newborns against laboratory-confirmed pertussis infection. A matched case-control study was undertaken in the period between 1 March 2015 and 29 February 2016. Twenty-two cases and 66 controls (+/- 15 days of age difference) were included in the study. Cases were non-vaccinated infants < 3 months of age at disease onset testing positive for pertussis by real-time PCR...
June 1, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28598249/recall-and-decay-of-consent-information-among-parents-of-infants-participating-in-a-randomized-controlled-clinical-trial-using-an-audio-visual-tool-in-the-gambia
#6
Robert B Mboizi, Muhammed O Afolabi, Michael Okoye, Beate Kampmann, Anna Roca, Olubukola T Idoko
Communicating essential research information to low literacy research participants in Africa is highly challenging, since this population is vulnerable to poor comprehension of consent information. Several supportive materials have been developed to aid participant comprehension in these settings. Within the framework of a pneumococcal vaccine trial in The Gambia, we evaluated the recall and decay of consent information during the trial which used an audio-visual tool called 'Speaking Book', to foster comprehension among parents of participating infants...
June 9, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28594758/timing-of-etonogestrel-releasing-implants-and-growth-of-breastfed-infants-a-randomized-controlled-trial
#7
Lilian Sheila de Melo Pereira Carmo, Giordana Campos Braga, Rui Alberto Ferriani, Silvana Maria Quintana, Carolina Sales Vieira
OBJECTIVE: To evaluate the growth of breastfed infants whose mothers had inserted an etonogestrel-releasing implant in the immediate postpartum period. METHODS: An open, randomized controlled, and parallel trial of postpartum women who were block-randomized to early (up to 48 hours postpartum before discharge) or conventional (at 6 weeks postpartum) insertion of an etonogestrel implant. The primary outcome was average infant weight at 12 months (360 days) and a difference of equal to or greater than 10% between groups was considered clinically significant...
June 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28592607/maternal-dietary-intakes-of-refined-grains-during-pregnancy-and-growth-through-the-first-7-y-of-life-among-children-born-to-women-with-gestational-diabetes
#8
Yeyi Zhu, Sjurdur F Olsen, Pauline Mendola, Thorhallur I Halldorsson, Edwina H Yeung, Charlotta Granström, Anne A Bjerregaard, Jing Wu, Shristi Rawal, Jorge E Chavarro, Frank B Hu, Cuilin Zhang
Background: Refined grains, a major source of dietary carbohydrates, have been related to impaired glucose homeostasis and obesity. Emerging animal data suggest that in utero exposure to dietary refined carbohydrates may predispose offspring to an obese phenotype, indicating a potential role for nutritional programming in the early origins of obesity, but intergenerational human data are lacking.Objective: We prospectively investigated refined-grain intake during pregnancy in association with offspring growth through age 7 y among high-risk children born to women with gestational diabetes mellitus (GDM)...
June 7, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28592081/-comparison-of-transthoracic-or-percutaneous-balloon-pulmonary-valvuloplasty-in-the-therapy-of-pulmonary-valve-stenosis
#9
Y Q Xie, J Yan, Z D Hua, W B Ouyang, K J Pang, Y B Zhang, G J Zhang, S J Li
Objective: To compare the clinical outcome of patients with pulmonary valve stenosis underwent transthoracic and percutaneous balloon pulmonary valvuloplasty. Methods: Clinical data of 806 patients diagnosed as pulmonary valve stenosis underwent transthoracic(171 patients as group A)or percutaneous balloon pulmonary valvuloplasty (635 patients as Group B) in Fuwai Hospital from February 2006 to January 2016 were analyzed retrospectively. There were 72 males in group A (42.1%) and 344 males in group B (54.2%)...
June 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28579233/a-phase-2-randomized-observer-blind-placebo-controlled-dose-ranging-trial-of-aluminum-adjuvanted-respiratory-syncytial-virus-f-particle-vaccine-formulations-in-healthy-women-of-childbearing-age
#10
Allison August, Gregory M Glenn, Eloi Kpamegan, Somia P Hickman, Dewal Jani, Hanxin Lu, D Nigel Thomas, Judy Wen, Pedro A Piedra, Louis F Fries
OBJECTIVE: Respiratory syncytial virus (RSV) causes significant morbidity and mortality in infants. We are developing an RSV fusion (F) protein nanoparticle vaccine for immunization of third trimester pregnant women to passively protect infants through transfer of RSV-specific maternal antibodies. The present trial was performed to assess the immunogenicity and safety of several formulations of RSV F vaccine in 1-dose or 2-dose schedules. METHODS: Placebo, or vaccine with 60μg or 120μg RSV F protein and 0...
June 1, 2017: Vaccine
https://www.readbyqxmd.com/read/28575286/efficacy-of-maternal-influenza-vaccination-against-all-cause-lower-respiratory-tract-infection-hospitalizations-in-young-infants-results-from-a-randomized-controlled-trial
#11
Marta C Nunes, Clare L Cutland, Stephanie Jones, Sarah Downs, Adriana Weinberg, Justin R Ortiz, Kathleen M Neuzil, Eric A F Simões, Keith P Klugman, Shabir A Madhi
Background: Influenza immunization of pregnant women protects their young infants against laboratory-confirmed influenza infection. Influenza infection might predispose to subsequent bacterial infections that cause severe pneumonia. In a secondary analysis of a randomized clinical trial (RCT), we evaluated the effect of maternal vaccination on infant hospitalizations for all-cause acute lower respiratory tract infection (ALRI). Methods: Infants born to women who participated in a double-blind placebo-controlled RCT in 2011 and 2012 on the efficacy of trivalent inactivated influenza vaccine (IIV) during pregnancy were followed during the first 6 months of life...
May 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28574538/empiric-listeria-monocytogenes-antibiotic-coverage-for-febrile-infants-age-0-90-days
#12
REVIEW
John R Stephens, Michael J Steiner
No abstract text is available yet for this article.
June 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28557739/epidemiology-of-cerebrospinal-fluid-cultures-and-time-to-detection-in-term-infants
#13
Rianna Leazer, Natasha Erickson, James Paulson, Ronen Zipkin, Monica Stemmle, Alan R Schroeder, Michael Bendel-Stenzel, Bryan R Fine
BACKGROUND: Although meningitis is rare in previously healthy term infants, lumbar puncture is often performed to evaluate for source of illness. This study was performed to determine the time to detection for positive cerebrospinal fluid (CSF) cultures and to provide an update on the current epidemiology of bacterial meningitis in term infants. METHODS: This study was a multicenter, retrospective review of positive CSF cultures in infants ≤90 days of age. Specimens were drawn in the emergency department or inpatient setting between January 2000 and December 2013...
May 2017: Pediatrics
https://www.readbyqxmd.com/read/28549589/serum-retinol-levels-and-neonatal-outcomes-in-preterm-infants
#14
Hsing-Jin Chen, Chyong-Hsin Hsu, Bor-Luen Chiang
BACKGROUND: Glucocorticoids are frequently administered to preterm infants, both antenatally and postnatally; however, the effect on serum retinol levels has not been determined. The risk of bronchopulmonary dysplasia is increased in premature infants with low retinol concentrations. OBJECTIVES: Our purpose was to determine the effect of glucocorticoid administration on serum retinol levels in preterm infants. METHODS: All infants <1250 g or <29 weeks' gestation admitted to the neonatal intensive care unit within 48 h of birth were eligible for inclusion...
May 23, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28545876/impact-of-periconceptional-folic-acid-supplementation-on-low-birth-weight-and-small-for-gestational-age-infants-in-china-a-large-prospective-cohort-study
#15
Nan Li, Zhiwen Li, Rongwei Ye, Jianmeng Liu, Aiguo Ren
OBJECTIVES: To explore the effects of maternal folic acid supplementation alone during pregnancy on the incidence of low birth weight (LBW) and small-for-gestational-age (SGA) infant status. STUDY DESIGN: Data were derived from a large population-based cohort study performed in China to evaluate the prevention of neural tube defects with folic acid supplementation. The sample comprised 200 589 singleton live births registered in 2 southern Chinese provinces by mothers for whom detailed information on folic acid use was available...
May 22, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28500462/perfusion-index-and-left-ventricular-output-correlation-in-healthy-term-infants
#16
Iuri Corsini, Alessandra Cecchi, Caterina Coviello, Carlo Dani
Perfusion index (PI) is a non-invasive marker of peripheral perfusion which is detected by an oximeter. We aimed to assess the correlation between PI and left ventricular output (LVO) in healthy term infants at the time of the screening for congenital heart disease (CHD). PI was measured at 48 ± 2 h of life in the infant's right hand (PIrh) and in 1 foot (PIf) contemporary to SpO2 for CHD screening. Heart ultrasound was performed immediately after the screening procedure for measuring LVO. Forty-nine healthy term infants were studied...
May 12, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28471089/transcatheter-closure-of-hemodynamic-significant-patent-ductus-arteriosus-in-32-premature-infants-by-amplatzer-ductal-occluder-additional-size-adoiias
#17
Patrice Morville, Ahmad Akhavi
OBJECTIVES: The advent of Amplatzer Duct Occluder II additional Size (ADOIIAS) provided the potential to close hemodynamic significant patent ductus arteriosus (HSPDA) and to analyze the feasibility, safety and efficacy of the device. BACKGROUND: Treatment of a patent ductus arteriosus (PDA) in very premature neonates is still a dilemma for the neonatalogist who has to consider its significance and has to choose among different treatment options. Because surgical ligation and medical therapy both have their drawbacks, interventional catheterization might provide an alternative means of closing HSPDA...
May 4, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28456376/-consultation-liaison-during-the-peripartum-network-care-between-liaison-and-mobile-unit
#18
V Garez, E Devouche, A Bobin-Bègue, M Alecian, P Minjollet, A Vallerent, M Poget, H Oguibenine, C Héroux, F Medjkane, G Apter
OBJECTIVES: The pregnancy periods of peripartum and immediate postpartum represent moments of opportunity to access care. Both prevention and therapeutic management can be offered with a better chance of success during these periods. Our specific Consultation Liaison (CL) team PPUMMA was created in order to respond to the need for early detection of psychopathology and rapid implementation of therapeutic management and preventive measure for mother and child. The importance of urgently intervening "on site" seemed a necessity since duration of hospitalization in maternity wards is very short...
April 26, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28448569/dynamics-and-complexity-of-body-temperature-in-preterm-infants-nursed-in-incubators
#19
Kerstin Jost, Isabelle Pramana, Edgar Delgado-Eckert, Nitin Kumar, Alexandre N Datta, Urs Frey, Sven M Schulzke
BACKGROUND: Poor control of body temperature is associated with mortality and major morbidity in preterm infants. We aimed to quantify its dynamics and complexity to evaluate whether indices from fluctuation analyses of temperature time series obtained within the first five days of life are associated with gestational age (GA) and body size at birth, and presence and severity of typical comorbidities of preterm birth. METHODS: We recorded 3h-time series of body temperature using a skin electrode in incubator-nursed preterm infants...
2017: PloS One
https://www.readbyqxmd.com/read/28425590/role-of-upper-gastrointestinal-contrast-studies-for-suspected-malrotation-in-neonatal-population
#20
Suresh Birajdar, Shripada C Rao, Fiona Bettenay
AIM: Upper gastrointestinal (UGI) contrast study is the preferred radiological investigation to diagnose malrotation of intestine. We aimed to review the role of UGI contrast in neonates (term and preterm) who were clinically suspected to have malrotation. METHODS: The study included a retrospective review of medical charts and radiology reports. RESULTS: A total of 164 newborn infants underwent UGI contrast study to rule out malrotation during the study period (2006-2015)...
April 20, 2017: Journal of Paediatrics and Child Health
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