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Exercise is medicine

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https://www.readbyqxmd.com/read/29783246/-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B1-%C3%B0%C2%BA-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B1-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0
#1
Nataliia O Rynhach, Vasyl M Mykhalchuk, Anatolii H Krut
OBJECTIVE: Introduction: This publication focuses on role of physical activity in promoting and protecting health and well-being. Physical activity is a significant risk factor for noncommunicable diseases. The public's awareness of the risk factors of non-communicable diseases is an important component of their control. The aim: To estimate the level of knowledge of the working age population regarding the essence of a healthy lifestyle and risk factors for non-communicable diseases (with an emphasis on lack of physical activity and its consequences) according to qualitative and quantitative sociological research...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29774312/breast-cancer-prevention-current-approaches-and-future-directions
#2
REVIEW
Edward R Sauter
The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential approaches that could be used in the future. This review does not discuss early detection strategies for breast cancer, including breast cancer screening. The breast is the most common site among women worldwide of noncutaneous cancer. Many clinical and genetic factors have been found to increase a woman's risk of developing the disease...
April 2018: European journal of breast health
https://www.readbyqxmd.com/read/29773272/juvenile-dermatomyositis-latest-advances
#3
REVIEW
Qiong Wu, Lucy R Wedderburn, Liza J McCann
Registries and biobanks for juvenile dermatomyositis (JDM) have generated statistical power to help understand pathogenesis and determine treatment and long-term outcomes in this rare and heterogeneous disease. Genotype, autoantibodies, muscle histology and early clinical features may predict prognosis and guide personalised treatment. While corticosteroids and disease-modifying anti-rheumatic drugs improve outcomes, there remain children who experience refractory disease. Ongoing research into the aberrant immune response and novel biological targets is necessary...
August 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29771450/effects-of-intense-aerobic-exercise-and-or-antihypertensive-medication-in-individuals-with-metabolic-syndrome
#4
M Ramirez-Jimenez, F Morales-Palomo, J F Ortega, R Mora-Rodriguez
We studied the blood pressure lowering effects of a bout of exercise and/or antihypertensive medicine with the goal of studying if exercise could substitute or enhance pharmacologic hypertension treatment. Twenty-three hypertensive metabolic syndrome patients chronically medicated with angiotensin II receptor 1 blockade antihypertensive medicine underwent 24-hr monitoring in four separated days in a randomized order; a) after taking their habitual dose of antihypertensive medicine (AHM trial), b) substituting their medicine by placebo medicine (PLAC trial), c) placebo medicine with a morning bout of intense aerobic exercise (PLAC+EXER trial) and d) combining the exercise and antihypertensive medicine (AHM+EXER trial)...
May 17, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29769433/medical-imaging-dose-optimization-from-ground-up-expert-opinion-of-an-international-summit
#5
Ehsan Samei, Hannu Jarvinen, Mika Kortesniemi, Georgios Simantirakis, Charles Goh, Anthony Wallace, Eliseo Vano, Adrian Bejan, M M Rehani, J Vassileva
As in any medical intervention, there is either a known or an anticipated benefit to the patient from undergoing a medical imaging procedure. This benefit is generally significant as demonstrated by the manner in which medical imaging has transformed clinical medicine. At the same time, when it comes to imaging that deploys ionizing radiation, there is a potential associated risk from radiation. Radiation risk has been recognized as a key liability in the practice of medical imaging, creating a motivation for radiation dose optimization...
May 17, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29768290/intense-aerobic-exercise-lowers-blood-pressure-in-individuals-with-metabolic-syndrome-taking-antihypertensive-medicine
#6
Miguel Ramirez-Jimenez, Valentin Fernandez-Elias, Felix Morales-Palomo, Juan F Ortega, Ricardo Mora-Rodriguez
OBJECTIVE: There is a growing tendency for physicians to prescribe exercise in accordance with the 'exercise is medicine' global health initiative. However, the exercise-pharmacologic interactions for controlling blood pressure are not well described. Our purpose was to study whether angiotensin II receptor type 1 blocker (ARB) antihypertensive medicine enhances the blood pressure-lowering effects of intense exercise. PARTICIPANTS AND METHODS: Fifteen hypertensive individuals with metabolic syndrome chronically medicated with ARB underwent two exercise trials in a blind randomized order...
May 15, 2018: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29766628/health-professional-student-education-related-to-the-prevention-of-falls-in-older-people-a-survey-of-universities-in-australia-and-new-zealand
#7
Esther Vance, Melanie K Farlie, Bridget Kool, Anne Tiedemann, Anna L Hatton, Catherine Sherrington, Daina L Sturnieks
OBJECTIVE: To determine the amount and nature of health professional education related to fall prevention for older adults in Australian and New Zealand universities. METHODS: Universities offering medicine, nursing and allied health courses were invited to complete an online survey enquiring about fall prevention course-related information: topics; delivery mode; and time dedicated. RESULTS: One hundred and five respondents, 11 disciplines and 43 universities completed the survey...
May 15, 2018: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29764892/intense-exercise-for-survival-among-men-with-metastatic-castrate-resistant-prostate-cancer-interval-gap4-a-multicentre-randomised-controlled-phase-iii-study-protocol
#8
Robert U Newton, Stacey A Kenfield, Nicolas H Hart, June M Chan, Kerry S Courneya, James Catto, Stephen P Finn, Rosemary Greenwood, Daniel C Hughes, Lorelei Mucci, Stephen R Plymate, Stephan F E Praet, Emer M Guinan, Erin L Van Blarigan, Orla Casey, Mark Buzza, Sam Gledhill, Li Zhang, Daniel A Galvão, Charles J Ryan, Fred Saad
INTRODUCTION: Preliminary evidence supports the beneficial role of physical activity on prostate cancer outcomes. This phase III randomised controlled trial (RCT) is designed to determine if supervised high-intensity aerobic and resistance exercise increases overall survival (OS) in patients with metastatic castrate-resistant prostate cancer (mCRPC). METHODS AND ANALYSIS: Participants (n=866) must have histologically documented metastatic prostate cancer with evidence of progressive disease on androgen deprivation therapy (defined as mCRPC)...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29764877/efficacy-of-practising-tai-chi-for-older-people-with-mild-dementia-protocol-for-a-randomised-controlled-study
#9
Jihui Lyu, Wenjie Li, Xiangjiang Rong, Lian Wei, Nayan Huang, Mei Champ, Qian Xiong, Xueli Chen, Mo Li, Fangling Li
INTRODUCTION: Many studies suggest that Tai Chi exercise is a safe and appropriate mind-body exercise for older people and effectively slows down age-related cognitive decline. A set of bespoke Tai Chi exercise named 'Cognition Protecting Tai Chi' (CPT) has been created for older people with cognitive impairments by the research team of geriatricians, neurologists, rehabilitation specialists, experts of sports medicine and experienced practitioners of traditional Chinese medicine. This trial is designed to evaluate its effects on cognitive function, behaviour/moods, risk of falls and activities of daily living of the participants with mild dementia...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29755757/need-to-improve-awareness-and-treatment-compliance-in-high-risk-patients-for-diabetic-complications-in-nepal
#10
Raju P Sapkota, Tirthalal Upadhyaya, Govind Gurung, Mike Parker, Rajiv Raman, Shahina Pardhan
Objective/introduction: It is known that knowledge, awareness, and practice influence diabetic control. We compared factors pertaining to healthy lifestyle (exercising, avoiding smoking), self-help (attending appointments, following treatment regimens), and diabetic awareness in high-risk patients for diabetic complications, specifically, those on insulin versus non-insulin treatment, and also those with a longer diabetic duration (≥5 years) versus a shorter duration. Methods: 200 consecutive patients with type 2 diabetes (52...
2018: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/29755739/abdominal-obesity-and-metabolic-syndrome-exercise-as-medicine
#11
REVIEW
Carole A Paley, Mark I Johnson
Background: Metabolic syndrome is defined as a cluster of at least three out of five clinical risk factors: abdominal (visceral) obesity, hypertension, elevated serum triglycerides, low serum high-density lipoprotein (HDL) and insulin resistance. It is estimated to affect over 20% of the global adult population. Abdominal (visceral) obesity is thought to be the predominant risk factor for metabolic syndrome and as predictions estimate that 50% of adults will be classified as obese by 2030 it is likely that metabolic syndrome will be a significant problem for health services and a drain on health economies...
2018: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29753424/-assessment-of-medical-management-of-heart-failure-at-national-hospital-blaise-compaore
#12
Y Kambiré, L Konaté, I Diallo, G R C Millogo, K J Kologo, J B Tougouma, A K Samadoulougou, P Zabsonré
AIM: The aim of this study was to assess the quality of medical management of heart failure at the National Hospital Blaise Compaoré according to the international guidelines. PATIENTS AND METHODS: A retrospective study was performed including consecutive patients admitted for heart failure documented sonographically from October 2012 to March 2015 in the Medicine and Medical Specialties Department of National Hospital Blaise Compaore with a minimum follow-up of six weeks...
May 9, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29752803/a-pragmatic-application-of-the-re-aim-framework-for-evaluating-the-implementation-of-physical-activity-as-a-standard-of-care-in-health-systems
#13
Mark Stoutenberg, Karla I Galaviz, Felipe Lobelo, Elizabeth Joy, Gregory W Heath, Adrian Hutber, Paul Estabrooks
INTRODUCTION: Exercise is Medicine (EIM) is an initiative that seeks to integrate physical activity assessment, prescription, and patient referral as a standard in patient care. Methods to assess this integration have lagged behind its implementation. PURPOSE AND OBJECTIVES: The purpose of this work is to provide a pragmatic framework to guide health care systems in assessing the implementation and impact of EIM. EVALUATION METHODS: A working group of experts from health care, public health, and implementation science convened to develop an evaluation model based on the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework...
May 10, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29750398/body-composition-fatigue-and-exercise-in-patients-with-prostate-cancer-undergoing-androgen-deprivation-therapy
#14
Robert U Newton, Emily Jeffery, Daniel A Galvão, Carolyn McIntyre, Nigel Spry, David Joseph, Jim Denham, Dennis R Taaffe
OBJECTIVES: To investigate the association between lean mass (LM) and fat mass (FM) with fatigue and vitality before and following exercise in patients with prostate cancer already undergoing androgen deprivation therapy (ADT). SUBJECTS AND METHODS: Cross-sectional associations between lean and fat mass with fatigue and/or vitality measures were examined in 229 patients (43-90 years). Prospective analysis was undertaken in 129 patients who underwent 3-6 months exercise (predominantly resistance + aerobic)...
May 11, 2018: BJU International
https://www.readbyqxmd.com/read/29741196/educating-medical-students-in-counselling-older-adults-about-exercise-the-impact-of-a-physical-activity-module
#15
A D Jadczak, K L Tam, R Visvanathan
BACKGROUND: Exercise courses during medical school contribute to medical students' confidence in promoting physical activity to their patients. However, there is still a lack of uniform physical activity education across medical school curricula to equip medical students with the necessary skills and knowledge to counsel their patients about exercise. OBJECTIVE: To determine the effects of a 1.5-hour physical activity module including a one-hour exercise tutorial combined with a 30-minute practical counselling session on senior medical students' perceptions of the importance of exercise and their perceived competence in advising older people about exercise...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29740341/circulating-mirnas-as-putative-biomarkers-of-exercise-adaptation-in-endurance-horses
#16
Katia Cappelli, Stefano Capomaccio, Andrea Viglino, Maurizio Silvestrelli, Francesca Beccati, Livia Moscati, Elisabetta Chiaradia
Endurance exercise induces metabolic adaptations and has recently been reported associated with the modulation of a particular class of small noncoding RNAs, microRNAs, that act as post-transcriptional regulators of gene expression. Released into body fluids, they termed circulating miRNAs, and they have been recognized as more effective and accurate biomarkers than classical serum markers. This study examined serum profile of miRNAs through massive parallel sequencing in response to prolonged endurance exercise in samples obtained from four competitive Arabian horses before and 2 h after the end of competition...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29739387/variability-and-dimensionality-of-students-and-supervisors-mini-cex-scores-in-undergraduate-medical-clerkships-a-multilevel-factor-analysis
#17
Christoph Berendonk, Anja Rogausch, Armin Gemperli, Wolfgang Himmel
BACKGROUND: The mini clinical evaluation exercise (mini-CEX)-a tool used to assess student-patient encounters-is increasingly being applied as a learning device to foster clinical competencies. Although the importance of eliciting self-assessment for learning is widely acknowledged, little is known about the validity of self-assessed mini-CEX scores. The aims of this study were (1) to explore the variability of medical students' self-assessed mini-CEX scores, and to compare them with the scores obtained from their clinical supervisors, and (2) to ascertain whether learners' self-assessed mini-CEX scores represent a global dimension of clinical competence or discrete clinical skills...
May 8, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29737299/intervention-and-effect-analysis-of-achyranthes-bidentata-blume-combined-with-aerobic-exercise-to-interfere-with-type-2-diabetes
#18
Chi Ma, Chengtao Zhang, Xin Li
With the continuous progress of traditional Chinese medicine extraction technology in recent years, the active components of traditional Chinese medicine have been continuously extracted and analyzed. In this paper, the authors studied the effect of aerobic exercise combined with the extract of the Achyranthes bidentata on the serum indexes of T2DM rats. Through systematic analysis of measurement indexes of Chinese medicine treatment group, we found that all indexes of FPG, INS, NOXs, ROS and SOD all showed a marked improvement, which fully proved the effect of Achyranthes bidentata extract on improving the condition of rats with type 2 diabetes mellitus...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29735466/intervention-and-effect-analysis-of-achyranthes-bidentata-blume-combined-with-aerobic-exercise-to-interfere-with-type-2-diabetes
#19
Chi Ma, Chengtao Zhang, Xin Li
With the continuous progress of traditional Chinese medicine extraction technology in recent years, the active components of traditional Chinese medicine have been continuously extracted and analyzed. In this paper, the authors studied the effect of aerobic exercise combined with the extract of the Achyranthes bidentata on the serum indexes of T2DM rats. Through systematic analysis of measurement indexes of Chinese medicine treatment group, we found that all indexes of FPG, INS, NOXs, ROS and SOD all showed a marked improvement, which fully proved the effect of Achyranthes bidentata extract on improving the condition of rats with type 2 diabetes mellitus...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29735394/dorzagliatin-monotherapy-in-chinese-patients-with-type-2-diabetes-a-dose-ranging-randomised-double-blind-placebo-controlled-phase-2-study
#20
Dalong Zhu, Shenglian Gan, Yu Liu, Jianhua Ma, Xiaolin Dong, Weihong Song, Jiao'e Zeng, Guixia Wang, Wenjuan Zhao, Qiu Zhang, Yukun Li, Hui Fang, Xiaofeng Lv, Yongquan Shi, Haoming Tian, Linong Ji, Xin Gao, Lihui Zhang, Yuqian Bao, Minxiang Lei, Ling Li, Longyi Zeng, Xiaoying Li, Xinghua Hou, Yu Zhao, Tianxin Hu, Xiaoyun Ge, Guiyu Zhao, Yongguo Li, Yi Zhang, Li Chen
BACKGROUND: Glucokinase acts as a glucose sensor in the pancreas and a glucose processor in the liver, and has a central role in glucose homoeostasis. Dorzagliatin is a new, dual-acting, allosteric glucokinase activator that targets both pancreatic and hepatic glucokinases. Dorzagliatin has good pharmacokinetic and pharmacodynamic properties in humans, and provides effective 24-h glycaemic control and improves glucose sensitivity in patients with type 2 diabetes. We aimed to assess the efficacy and safety of dorzagliatin monotherapy at different doses in Chinese patients with type 2 diabetes...
May 4, 2018: Lancet Diabetes & Endocrinology
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