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https://www.readbyqxmd.com/read/29016927/clinical-use-of-pregabalin-in-general-practice-in-catalonia-spain-a-population-based-cross-sectional-study
#1
Montserrat Viñas-Bastart, Míriam Oms-Arias, Àfrica Pedraza-Gutiérrez, Irene Lizano-Díez, Pilar Modamio, Eduardo L Mariño
Objective: The aim of this study was to determine the pattern of use of pregabalin and the appropriateness of treatment, so that interventions could be designed to improve various clinical approaches to the use of pregabalin to include unlicensed indications. Design: A descriptive, cross-sectional, multicenter study was performed between April 2014 and January 2015. Setting: Fifty-three primary health care centers covering 1,250,000 inhabitants...
July 17, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28991699/microglial-macrophage-markers-chi3l1-scd14-and-scd163-in-csf-and-serum-of-pediatric-inflammatory-and-non-inflammatory-neurological-disorders-a-case-control-study-and-reference-ranges
#2
Michael R Pranzatelli, Elizabeth D Tate, Nathan R McGee
OBJECTIVE: To assess the role of microglia and macrophages in neuroinflammatory disorders in children via biomarkers, and establish control reference ranges. METHODS: In an IRB-approved case-control study of 98 children, the concentrations of CSF/serum CHI3L1, sCD14, and sCD163 were measured by ELISA. Groups were controls (non-inflammatory neurological disorders, NIND, n=37), opsoclonus-myoclonus syndrome (OMS, n=37), and other inflammatory neurological disorders (OIND, n=24)...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28988639/can-we-keep-the-md-program-within-reach-of-oms
#3
EDITORIAL
Mark Engelstad
No abstract text is available yet for this article.
July 27, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28971571/clinicopathological-features-of-neuroblastic-tumors-with-opsoclonus-myoclonus-ataxia-syndrome-follicular-structure-predicts-a-better-neurological-outcome
#4
Hiroko Fukushima, Takeshi Inoue, Yuichi Takama, Naomi Ishii, Takahiro Okuno, Yasutsugu Kobayashi, Akihiro Yoneda, Tetsuro Nakamura, Ichiro Kuki, Junichi Hara
Neuroblastic tumors (NT) with opsoclonus-myoclonus syndrome (OMS) display characteristic histological features, such as lymphocytic infiltration with lymphoid follicles, indicating an underlying immune response. We retrospectively assessed NT patients from 2001 to 2016. Five cases of NT with OMS and 76 cases of NT without OMS were histopathologically reviewed in this study. The grade of lymphocytic infiltration was evaluated. The number of follicles was counted and the presence or absence of lymphoid follicles was recorded for each case...
October 2017: Pathology International
https://www.readbyqxmd.com/read/28969666/why-we-don-t-want-another-synthesis
#5
Arlin Stoltzfus
High-level debates in evolutionary biology often treat the Modern Synthesis as a framework of population genetics, or as an intellectual lineage with a changing distribution of beliefs. Unfortunately, these flexible notions, used to negotiate decades of innovations, are now thoroughly detached from their historical roots in the original Modern Synthesis (OMS), a falsifiable scientific theory. The OMS held that evolution can be adequately understood as a process of smooth adaptive change by shifting the frequencies of small-effect alleles at many loci simultaneously, without the direct involvement of new mutations...
October 2, 2017: Biology Direct
https://www.readbyqxmd.com/read/28959231/demographic-clinical-and-immunologic-features-of-389-children-with-opsoclonus-myoclonus-syndrome-a-cross-sectional-study
#6
Michael R Pranzatelli, Elizabeth D Tate, Nathan R McGee
Pediatric-onset opsoclonus-myoclonus syndrome (OMS) is a devastating neuroinflammatory, often paraneoplastic, disorder. The objective was to characterize demographic, clinical, and immunologic aspects in the largest cohort reported to date. Cross-sectional data were collected on 389 children in an IRB-approved, observational study at the National Pediatric Myoclonus Center. Non-parametric statistical analysis was used. OMS manifested in major racial/ethnic groups, paralleling US population densities. Median onset age was 1...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28957743/monodisperse-manganese-oxide-nanoparticles-synthesis-characterization-and-chemical-reactivity
#7
Tetsuro Soejima, Kazuki Nishizawa, Ryosuke Isoda
Highly monodisperse amorphous manganese oxide (MnOx) nanospheres with diameter of ca. 300nm have been obtained from ammonia aqueous solution of KMnO4 at room temperature. The amorphous MnOx nanospheres successfully converted to monodisperse K-OMS-2 (cryptomelane) and K-OMS-2/Mn2O3 nanoraspberries through calcination process at 600 and 800°C, respectively. Analyzing the structure of such amorphous MnOx has been a challenge because fewer reports are available to examine amorphous structure. Thus, shape, crystallinity, and structure of the amorphous and crystalline MnOx nanostructures were characterized in detail by X-ray diffraction (XRD), thermogravimetry/differential thermal analysis (TG/DTA), scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution TEM (HRTEM), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray Photoelectron Spectroscopy (XPS), and energy dispersive spectroscopy (EDS)...
September 22, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28951760/a-new-technique-using-low-volumes-a-new-technique-to-assess-the-molluscicidal-activity-using-low-volumes
#8
José Augusto Albuquerque Santos, Viviane Paixão Cavalcante, Leonardo da Silva Rangel, João Claudio Vitória Atico Leite, Robson Xavier Faria
Schistosomiasis is a disease endemic in several states of Brazil. The population control of the transmitter mollusks is done with Bayluscide WP 70®, in the control programs. OMS preconize molluscicidal assays using Becker with 500 mL of final volume, restringing the number of natural products and synthetic drugs to be tested in function of high quantity of material necessary. A new technique to assess the toxic effects for Biomphalaria sp. is the purpose of this work, for developing adaptation for this aquatic organism, using a low volume of test solution in 24-well plates...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28944142/theory-and-practice-of-laparoscopic-surgery-against-omohyoid-muscle-syndrome
#9
Zhipeng Sun, Yubing Zhu, Nengwei Zhang
Omohyoid muscle syndrome (OMS) is a rare disease characterized as a protruding lateral neck mass feature during swallowing. Because there is a 5 cm scar after traditionally surgery, we designed a laparoscopic surgery procedure to meet the cosmetic needs of patients. From the year 2006 to 2016, there were 3 patients diagnosed as omohyoid muscle syndrome that underwent laparoscopic surgery. Operative and postoperative follow-up data were summarized. Average surgery time was 35 ± 13 min. Average blood loss was 3 ± 1 mL...
August 2017: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/28940443/aqueous-magnesium-ion-battery-based-on-carbon-coated-fevo4-as-anode-and-mg-oms-1-as-cathode-with-high-energy-density
#10
Hongyu Zhang, Ke Ye, Kai Zhu, Ruibai Cang, Jun Yan, Kui Cheng, Guiling Wang, Dianxue Cao
The porous FeVO4 is prepared by hydrothermal method and further modified by coating carbon to obtain the FeVO4/C with hierarchical pore structure, which are used as anodic electrodes in aqueous rechargeable magnesium ion battery. And the FeVO4/C material can not only improve the electrical conductivity by coating a carbon layer but also increase the specific surface area by hierarchical pore structure, which is more beneficial for magnesium ion insertion/deinsertion. Therefore, the aqueous rechargeable magnesium ion full battery is successfully constructed by FeVO4/C as anode, Mg-OMS-1 as cathode and in 1...
September 21, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28930329/impact-of-scill-catalysts-for-the-s-s-coupling-of-thiols-to-disulfides
#11
Octavian D Pavel, Iunia Podolean, Vasile I Parvulescu, S F Rebecca Taylor, Haresh G Manyar, Kathryn Ralphs, Peter Goodrich, Christopher Hardacre
This study reports the behaviour of SCILL based catalysts in the oxidative S-S coupling of aliphatic and aromatic thiols, namely 1-butanethiol and thiophenol, to dibutyl disulfide and diphenyl disulfide. A range of ionic liquids (1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide) and metal supported catalysts (5% Pt/SiO2; 5% Ru/SiO2; 5% Ru/C; 5% Pt/OMS-2) were used to prepare the SCILL catalysts and all were found to be active for the reaction following the trend 5% Pt-OMS-2 > 5% Pt/SiO2 > 5% Ru/C > 5% Ru/SiO2...
September 20, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28927956/the-correlation-between-periodontal-health-status-and-suspectibility-to-infections-associated-with-craniomaxillofacial-osteosynthesis-plates
#12
Yahya Açil, Marie-Annett Heitzer, Aydin Gülses, Hendrik Naujokat, Rainer Podschun, Jörg Wiltfang, Christian Flörke
AIM: The aim of the present study was to demonstrate the possible relation between periodontal health status and infections associated with osteosynthesis materials (OMs) used in the oral and maxillofacial reconstruction. MATERIAL AND METHODS: The study group consisted of 32 individuals which were subdivided into two groups regarding their PSI scores. After the removal of the osteosynthesis plates, microbial colonization was assessed via microbiological cultivation, fluorescence microscopy and scanning electron microscopy...
August 24, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28920993/cobalt-ii-containing-liquid-metal-salts-for-electrodeposition-of-cobalt-and-electrochemical-nanoparticle-formation
#13
Jeroen Sniekers, Pieter Geysens, João C Malaquías, Tom Vander Hoogerstraete, Luc Van Meervelt, Jan Fransaer, Koen Binnemans
Cobalt(ii)-containing liquid metal salts (LMS) with N-alkylimidazole ligands and bis(trifluoromethanesulfonyl)imide (bistriflimide, Tf2N(-)) or methanesulfonate (mesylate, OMs(-)) anions were synthesized and characterized. The chain length of the alkyl side chain on the imidazole ligand was varied. All compounds were characterized using CHN analysis, DSC and FTIR measurements. Single-crystal X-ray diffraction measurements were performed on six of the compounds for which single crystals of good quality could be obtained...
September 18, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28912384/-fracture-liaison-service-and-osteoporosis-liaison-service
#14
Hiroshi Hagino
Fracture Liaison Service(FLS)was initiated in the late 1990s in Europe then afterwards spread to North America and Australia. The aim of FLS is to prevent secondary fractures after fragility fractures. Because of its usefulness it has become a global success through proof of its high efficacy and cost-effectiveness. The Japan Osteoporosis Society(JOS)initiated Osteoporosis Liaison Service(OLS)in Japan. FLS and OLS have the same aim-to prevent secondary fractures; however, OSL also aims to prevent primary fractures in clinics and the community...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28910508/immobilizing-organic-based-molecular-switches-into-metal-organic-frameworks-a-promising-strategy-for-switching-in-solid-state
#15
REVIEW
Bo Gui, Yi Meng, Yang Xie, Ke Du, Andrew C-H Sue, Cheng Wang
Organic-based molecular switches (OMS) are essential components for the ultimate miniaturization of nanoscale electronics and devices. For practical applications, it is often necessary for OMS to be incorporated into functional solid-state materials. However, the switching characteristics of OMS in solution are usually not transferrable to the solid state, presumably because of spatial confinement or inefficient conversion in densely packed solid phase. A promising way to circumvent this issue is harboring the functional OMS within the robust and porous environment of metal-organic frameworks (MOFs) as their organic components...
September 14, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28905654/opsoclonus-myoclonus-syndrome-following-long-term-use-of-cyclosporine
#16
Hyun Goo Kang, Sung Kwang Park, Su Jeong Wang, Sun-Young Oh, Han Uk Ryu
BACKGROUND: Cyclosporine A (CsA) is a widely used immunosuppressive agent that may provoke unexpected neurologic complications. The mechanism is unclear and variable intervals have been reported between CsA administration and onset of the related side effects. Here, we describe a case of delayed-onset CsA neurotoxicity presenting as opsoclonus-myoclonus syndrome (OMS). CASE DETAILS: A 37-year-old woman with a two-week period of opsoclonus and upper extremity myoclonus was admitted to our hospital...
September 14, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28886356/african-americans-in-oral-and-maxillofacial-surgery-factors-affecting-career-choice-satisfaction-and-practice-patterns
#17
Thalia-Rae Criddle, Newton C Gordon, George Blakey, R Bryan Bell
PURPOSE: There are few data available on the experience of minority surgeons in the field of oral and maxillofacial surgery (OMS). Therefore, the purpose of this study was to 1) explore factors that contribute to African Americans choosing OMS as a career, 2) examine satisfaction among minority oral and maxillofacial surgeons with the residency application and training process, 3) report on practice patterns among minority oral and maxillofacial surgeons, and 4) identify perceived bias for or against minority oral and maxillofacial surgeons in an attempt to aid the efforts of OMS residency organizations to foster diversity...
August 12, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28882889/the-rho-adp-ribosylating-c3-exoenzyme-binds-cells-via-an-arg-gly-asp-motif
#18
Astrid Rohrbeck, Markus Höltje, Andrej Adolf, Elisabeth Oms, Sandra Hagemann, Gudrun Ahnert-Hilger, Ingo Just
The Rho ADP-ribosylating C3 exoenzyme (C3bot) is a bacterial protein toxin devoid of a cell-binding or -translocation domain. Nevertheless, C3 can efficiently enter intact cells, including neurons, but the mechanism of C3 binding and uptake is not yet understood. Previously, we identified the intermediate filament vimentin as an extracellular membranous interaction partner of C3. However, uptake of C3 into cells still occurs (although reduced) in the absence of vimentin, indicating involvement of an additional host cell receptor...
September 7, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28863910/influence-of-cortical-bone-thickness-on-miniscrew-microcrack-formation
#19
Melissa V Nguyen, John Codrington, Lloyd Fletcher, Craig W Dreyer, Wayne J Sampson
INTRODUCTION: The aim of this in-vitro study was to investigate the influence of cortical bone thickness on the amount of surface microdamage produced after insertion of orthodontic miniscrews (OM) in porcine tibia bone. METHODS: Aarhus OMs (Medicon, Tuttlingen, Germany; diameter, 1.5 mm; length, 6 mm) were inserted into 1.0 mm (group A; n = 10), 1.5 mm (group B; n = 10), and 2.0 mm (group C; n = 10) of porcine cortical bone using a torque-limiting hand screwdriver set at 18 Ncm...
September 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28846383/mannobiose-binding-induces-changes-in-hydrogen-bonding-and-protonation-states-of-acidic-residues-in-concanavalin-a-as-revealed-by-neutron-crystallography
#20
Oksana O Gerlits, Leighton Coates, Robert J Woods, Andrey Kovalevsky
Plant lectins are carbohydrate-binding proteins with various biomedical applications. Concanavalin A (Con A) holds promise in treating cancerous tumors. To better understand the Con A carbohydrate binding specificity, we obtained a room-temperature neutron structure of this legume lectin in complex with a disaccharide Manα1-2Man, mannobiose. The neutron structure afforded direct visualization of the hydrogen bonding between the protein and ligand, showing that the ligand is able to alter both protonation states and interactions for residues located close to and distant from the binding site...
September 12, 2017: Biochemistry
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