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https://www.readbyqxmd.com/read/29228517/cost-effectiveness-of-internet-based-cognitive-behavioral-treatment-for-bulimia-nervosa-results-of-a-randomized-controlled-trial
#1
Hunna J Watson, Nicole McLagan, Stephanie C Zerwas, Ross D Crosby, Michele D Levine, Cristin D Runfola, Christine M Peat, Markus Moessner, Benjamin Zimmer, Sara M Hofmeier, Robert M Hamer, Marsha D Marcus, Cynthia M Bulik, Scott J Crow
OBJECTIVE: To evaluate the cost-effectiveness of Internet-based cognitive-behavioral therapy for bulimia nervosa (CBT-BN) compared to face-to-face delivery of CBT-BN. METHODS: This study is a planned secondary analysis of data from a randomized clinical trial. Participants were 179 adults (98% female, mean age = 28 years) meeting DSM-IV criteria for bulimia nervosa who were randomized to group face-to-face or group Internet-based CBT-BN for 16 sessions during 20 weeks...
December 5, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29228509/c-learning-a-new-classification-framework-to-estimate-optimal-dynamic-treatment-regimes
#2
Baqun Zhang, Min Zhang
A dynamic treatment regime is a sequence of decision rules, each corresponding to a decision point, that determine that next treatment based on each individual's own available characteristics and treatment history up to that point. We show that identifying the optimal dynamic treatment regime can be recast as a sequential optimization problem and propose a direct sequential optimization method to estimate the optimal treatment regimes. In particular, at each decision point, the optimization is equivalent to sequentially minimizing a weighted expected misclassification error...
December 11, 2017: Biometrics
https://www.readbyqxmd.com/read/29228471/mass-spectrometry-for-protein-sialoglycosylation
#3
REVIEW
Qiwei Zhang, Zack Li, Yawei Wang, Qi Zheng, Jianjun Li
Sialic acids are a family of structurally unique and negatively charged nine-carbon sugars, normally found at the terminal positions of glycan chains on glycoproteins and glycolipids. The glycosylation of proteins is a universal post-translational modification in eukaryotic species and regulates essential biological functions, in which the most common sialic acid is N-acetyl-neuraminic acid (2-keto-5-acetamido-3,5-dideoxy-D-glycero-D-galactononulopyranos-1-onic acid) (Neu5NAc). Because of the properties of sialic acids under general mass spectrometry (MS) conditions, such as instability, ionization discrimination, and mixed adducts, the use of MS in the analysis of protein sialoglycosylation is still challenging...
December 11, 2017: Mass Spectrometry Reviews
https://www.readbyqxmd.com/read/29228339/thresholds-for-decision-making-informing-the-cost-effectiveness-and-affordability-of-rotavirus-vaccines-in-malaysia
#4
Tharani Loganathan, Chiu-Wan Ng, Way-Seah Lee, Raymond C W Hutubessy, Stéphane Verguet, Mark Jit
Cost-effectiveness thresholds (CETs) based on the Commission on Macroeconomics and Health (CMH) are extensively used in low- and middle-income countries (LMICs) lacking locally defined CETs. These thresholds were originally intended for global and regional prioritization, and do not reflect local context or affordability at the national level, so their value for informing resource allocation decisions has been questioned. Using these thresholds, rotavirus vaccines are widely regarded as cost-effective interventions in LMICs...
December 8, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29228295/assessment-of-patient-safety-culture-in-private-and-public-hospitals-in-peru
#5
Alejandro Arrieta, Gabriela Suárez, Galed Hakim
Objective: To assess the patient safety culture in Peruvian hospitals from the perspective of healthcare professionals, and to test for differences between the private and public healthcare sectors. Patient safety is defined as the avoidance and prevention of patient injuries or adverse events resulting from the processes of healthcare delivery. Design: A non-random cross-sectional study conducted online. Setting: An online survey was administered from July to August 2016, in Peru...
December 8, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29228293/providing-mental-health-care-for-the-complex-older-veteran-implications-for-social-work-practice
#6
Gayle Clark, Susan Rouse, Heather Spangler, Jennifer Moye
Mental health conditions are underdiagnosed and undertreated in older veterans, as with all older adults. Social workers bring an important perspective to the interdisciplinary team for the care of older veterans with mental health conditions. In this study authors assessed 50 older veterans referred for mental health treatment (mean age = 74.52 years, SD = 6.48) with standardized measures of depression, posttraumatic stress disorder (PTSD), and cognitive impairment. At initial assessment, 24 percent had moderate depression, 30 percent had PTSD, and 62 percent (n = 31) had (mostly mild) cognitive impairment based on cut scores...
December 8, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29228286/cut-and-paste-transposons-in-fungi-with-diverse-lifestyles
#7
Anna Muszewska, Kamil Steczkiewicz, Marta Stepniewska-Dziubinska, Krzysztof Ginalski
Transposons (TEs) shape genomes via recombination and transposition, lead to chromosomal rearrangements, create new gene neighbourhoods and alter gene expression. They play key roles in adaptation either to symbiosis in Amanita genus or to pathogenicity in Pyrenophora tritici-repentis. Despite growing evidence of their importance, the abundance and distribution of mobile elements replicating in a "cut and paste" fashion is barely described so far. In order to improve our knowledge on this old and ubiquitous class of transposable elements, 1,730 fungal genomes were scanned using both de novo and homology-based approaches...
December 8, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29227983/bone-conducted-vestibular-evoked-myogenic-potentials-before-and-after-stapes-surgery
#8
Kazuyuki Akazawa, Shigeto Ohta, Kenzo Tsuzuki, Masafumi Sakagami
OBJECTIVE: To identify whether stapes surgery causes otolith dysfunction using bone-conducted vestibular-evoked myogenic potentials (VEMPs). STUDY DESIGN: Prospective study. SETTING: Hyogo College of Medicine Hospital. PATIENTS: Twenty primary ears (19 otosclerosis, 1 congenital stapes fixation) in 17 patients (2 men, 15 women; mean age 51 yr, range 20-68 yr) who had normal cervical VEMP (cVEMP) and ocular VEMP (oVEMP) results with bone-conducted stimulation were included...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29227947/virtual-water-trade-of-agricultural-products-a-new-perspective-to-explore-the-belt-and-road
#9
Yu Zhang, Jin-He Zhang, Qing Tian, Ze-Hua Liu, Hong-Lei Zhang
The Belt and Road is an initiative of cooperation and development that was proposed by China. Moreover, most of the spanning countries faced water shortages and agriculture consumed a lot of water. Virtual water links water, food and trade and is an effective tool to ease water shortages. Therefore, this paper aims to understand the Belt and Road from the new perspective of virtual water trade of agricultural products. We considered agricultural products trade from 2001 to 2015. On the whole, the results indicated that China was in virtual water trade surplus with the countries along the Belt and Road...
December 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29227889/nursing-and-midwifery-students-stress-and-coping-during-their-undergraduate-education-programmes-an-integrative-review
#10
REVIEW
Bridie McCarthy, Anna Trace, Moira O'Donovan, Caroline Brady-Nevin, Margaret Murphy, Maria O'Shea, Patricia O'Regan
OBJECTIVES: The aim of this review is to examine the literature related to the sources of stress, coping mechanisms and interventions to support undergraduate nursing and midwifery students to cope with stress during their undergraduate education. DESIGN: Integrative literature review. DATA SOURCES: The databases CINAHL, PubMed and PsycINFO were searched for articles published between 2010 and 2016. Search terms in various combinations were used for example; student nurse, student midwife, undergraduate, stress, coping and interventions...
November 28, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29227841/becoming-enwinded-a-new-materialist-take-on-smoking-pleasure
#11
Simone Dennis
What might new materialist perspectives bring to our understanding of smoking pleasure? In this paper, I draw on this thinking to sketch out an alternative, non-unitary smoker who is at the mercy of the whims of the breeze - a yielding I will argue is key to smoking pleasure. With these intentions in mind, rather than thinking of what the biotechnology of cigarettes accomplishes in terms of the chemical delivery of pleasure, or adding to the multiply of social and cultural reasons anthropologists have tendered to account for it, I approach smoking pleasure in and through the medium of the smoky air...
December 8, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29227736/older-patients-recall-of-online-cancer-information-do-ability-and-motivation-matter-more-than-chronological-age
#12
Nadine Bol, Ellen M A Smets, Jacobus A Burgers, Suzy M Samii, Hanneke C J M De Haes, Julia C M Van Weert
This study proposes and tests a model to provide a more comprehensive understanding of the contribution of chronological age versus age-related ability and motivation factors in explaining recall of online cancer information among older patients (n = 197). Results revealed that recall is not a matter of chronological age per se, but rather a matter of ability and motivation. Age-related ability and motivation factors explained 37.9% of the variance in recall. Health literacy, involvement with the webpage, and satisfaction with the emotional support were positively associated with recall...
December 11, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/29227642/x-rays-in-the-cryo-em-era-structural-biology-s-dynamic-future
#13
Susannah Shoemaker, Nozomi Ando
Over the past several years, single-particle cryo-electron microscopy (cryo-EM) has emerged as a leading method for elucidating macromolecular structures at near-atomic resolution, rivaling even the established technique of X-ray crystallography. Cryo-EM is now able to probe proteins as small as hemoglobin (64 kDa), while avoiding the crystallization bottleneck entirely. The remarkable success of cryo-EM has called into question the continuing relevance of X-ray methods, particularly crystallography. To say that the future of structural biology is either cryo-EM or crystallography, however, would be misguided...
December 11, 2017: Biochemistry
https://www.readbyqxmd.com/read/29227581/aging-of-lymphoid-organs-can-photobiomodulation-reverse-age-associated-thymic-involution-via-stimulation-of-extrapineal-melatonin-synthesis-and-bone-marrow-stem-cells
#14
REVIEW
Denis Odinokov, Michael R Hamblin
Thymic atrophy and the subsequent reduction in T cell production are the most noticeable age-related changes affecting lymphoid organs in the immune system. In fact thymic involution has been described as "programmed aging". New therapeutic approaches such as photobiomodulation (PBM) may reduce or reverse these changes. PBM (also known as low-level laser therapy or LLLT) involves the delivery of non-thermal levels of red or near-infrared light that are absorbed by mitochondrial chromophores, in order to prevent tissue death and stimulate healing and regeneration...
December 11, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29227573/post-gwas-in-psychiatric-genetics-a-developmental-perspective-on-the-other-next-steps
#15
REVIEW
Danielle M Dick, Peter B Barr, Seung Bin Cho, Megan E Cooke, Sally I-Chun Kuo, Tenesha J Lewis, Zoe Neale, Jessica E Salvatore, Jeanne Savage, Jinni Su
As psychiatric genetics enters an era where gene identification is finally yielding robust, replicable genetic associations and polygenic risk scores, it is important to consider next steps and delineate how that knowledge will be applied to ultimately ameliorate suffering associated with substance use and psychiatric disorders. Much of the post-GWAS discussion has focused on the potential of genetic information to elucidate the underlying biology and use this information for the development of more effective pharmaceutical treatments...
December 11, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29227432/cpd-and-kt-models-used-and-opportunities-for-synergy
#16
Joan Sargeant, Francine Borduas, Anne Sales, Doug Klein, Brenna Lynn, Heather Stenerson
The two fields of continuing professional development (CPD) and knowledge translation (KT) within the health care sector, and their related research have developed as somewhat parallel paths with limited points of overlap or intersection. This is slowly beginning to change. The purpose of this paper is to describe and compare the dominant conceptual models informing each field with the view of increasing understanding and appreciation of the two fields, how they are similar and where they differ, and the current and potential points of intersection...
October 2017: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/29227420/us-state-public-health-departments-special-pathogen-planning
#17
Jocelyn J Herstein, Paul D Biddinger, Shawn G Gibbs, Aurora B Le, Katelyn C Jelden, Angela L Hewlett, John J Lowe
CONTEXT: US state public health departments played key roles in planning for and responding to confirmed and suspected cases of Ebola virus disease (EVD) during the 2014-2016 outbreak, including designating select hospitals as high-level isolation units (HLIUs) for EVD treatment in conjunction with the Centers for Disease Control and Prevention. OBJECTIVE: To identify existing guidelines and perspectives of state health departments pertaining to the management and transport of patients with EVD and other highly hazardous communicable diseases (HHCDs)...
December 7, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29227360/the-importance-of-specific-workplace-environment-characteristics-for-maximum-health-and-performance-healthcare-workers-perspective
#18
Rana Sagha Zadeh, Mardelle M Shepley, Arthur Hamie Owora, Martha C Dannenbaum, Laurie T Waggener, Susan Sung Eun Chung
OBJECTIVE: To examine the importance of specific workplace environment characteristics for maximum health and performance, assigned by healthcare employees, and how they relate to the nature of their work. METHODS: A cross-sectional mixed-method study was conducted with content analysis and robust regression models to examine the relationship between workplace environment characteristics and perceived importance in promoting health and performance. RESULTS: Our findings suggest that perceptions of key environment characteristics that safeguard health and performance in healthcare workplaces may vary by employee sex, setting, and nature of healthcare work involved...
December 8, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29227338/associations-between-early-family-meal-environment-quality-and-later-well-being-in-school-age-children
#19
Marie-Josée Harbec, Linda S Pagani
OBJECTIVE: Past research suggests a positive link between family meals and child and adolescent health. Although researchers have often relied on how often families eat together, this may not capture the complexity of the experience. Using a birth cohort, this study examines the prospective associations between the environmental quality of the family meal experience at age 6 years and child well-being at age 10. METHODS: Participants are 1492 children of the Quebec Longitudinal Study of Child Development...
December 5, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29227255/-perspective-management-in-the-treatment-of-genital-endometriosis-in-women-with-polymorphism-of-gens-gstt1-and-gstm1
#20
L Malanchuk, V Martynyuk, I Malanchyn, Z Kuchma, L Krasnyanska
The article covers the management of patients with internal genital endometriosis, in which the polymorphism of the glutathione-S-transferase genes has been diagnosed. The aim of our study was to select the optimal conservative method for treatment of internal genital endometriosis in women of reproductive age by developing complex therapy taking into account the polymorphism of the genes of the detoxification system. 102 patients with combined gynecological pathology were examined. All patients were subject to a dynamic clinical and laboratory examination...
November 2017: Georgian Medical News
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