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https://www.readbyqxmd.com/read/29668135/-costs-of-chagas-disease-screening-test-in-blood-donors-in-two-colombian-blood-banks-2015
#1
Nelson José Alvis, Diana Patricia Díaz, Liliana Castillo, Nelson Rafael Alvis, María Isabel Bermúdez, Olga Maritza Berrío, Mauricio Beltrán, Carlos Andrés Castañeda-Orjuela
INTRODUCTION: Transfusion is a mechanism of transmission of Chagas' disease. There are no studies on the costs of the screening test in Colombian blood banks. OBJECTIVE: To estimate the costs of the screening test for Chagas' disease among blood donors in two Colombian blood banks, 2015. MATERIALS AND METHODS: We conducted a micro-costing study from the perspective of the health care provider to estimate the cost of Chagas' disease testing in two blood banks, Banco de Sangre de la Cruz Roja, Seccional Bolívar, and Banco de Sangre del Hospital de Yopal, Casanare, taking into account four cost categories: 1) Administrative costs: public services and insurance costs were calculated based on the blood bank area in square meters; 2) capital costs: building and equipment costs that were annualized using a 3% discount rate and a lifespan of 20 years for building and five for equipment; 3) costs of Chagas' disease test materials and reagents adjusted by blood bank production level, and 4) costs of staff in charge of Chagas' disease test processing...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29667934/brain-computer-interaction-for-online-enhancement-of-visuospatial-attention-performance
#2
Romain Trachel, Thomas Brochier, Maureen Clerc
OBJECTIVE: the goal of this study is to investigate whether BCI that decode the location of covert attention can be leveraged to enhance visuospatial attention performance. Here, the covert attention task is to discriminate the orientation of a low-contrast target embedded in dynamic noise. Visuospatial attention performance is measured by the reaction time and the accuracy of target discrimination. APPROACH: The target location is indicated by a central cue made of randomly moving dots providing either predictive or ambiguous information...
April 18, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29667916/fiscal-impact-of-smoking-cessation-in-thailand-a-government-perspective-cost-benefit-analysis
#3
Mark P Connolly, Nikolaos Kotsopoulos, Pichaya Suthipinijtham, Suthat Rungruanghiranya
We evaluate the broader public economic consequences of investments in smoking cessation that change lifetime productivity, which can influence future government tax revenue and social transfer costs and health care spending. The analysis applies a government perspective framework for assessing the intergenerational relationships between morbidity and mortality and lifetime tax revenue and social transfers received. Applying smoking prevalence in Thailand, a cohort model was developed for smoker and former smokers to estimate impact on lifetime direct taxes and tobacco taxes paid...
April 1, 2018: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/29667878/safety-challenges-and-improvement-strategies-of-ethnic-minority-construction-workers-a-case-study-in-hong-kong
#4
Chunlin Wu, Xiaowei Luo, Tao Wang, Yue Wang, Bibek Sapkota
Due to cultural differences, ethnic minority construction workers are more difficult to manage and more vulnerable to accidents. This study aims to identify the major barriers faced by ethnic minority workers from their own perspectives and determine potential strategies to enhance safety climate of construction projects, thus ultimately improve their safety performance. A survey with modified Nordic safety climate questionnaire was conducted in a certain sub-contractor in Hong Kong. In-depth interviews, status quo description, major challenge investigation and safety knowledge tests were carried as well...
April 18, 2018: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/29667863/leo-kanner-and-autism-a-75-year-perspective
#5
James Harris
In 1943, Leo Kanner published the first systematic description of early infantile autism. He concluded that this was a neurodevelopmental disorder and that 'these children have come into the world with an innate inability to form the usual, biologically provided contact with people'. Moreover, his astute descriptions of parental behavior in his first publications were prescient and underlie later recognition of the importance of genetics. Our understanding has grown over the ensuing years with revisions in diagnostic classification, recognition of the broader autism phenotype in families, appreciation of the importance of developmental models, advances in genetic methodology, better understanding of the relationship to intellectual deficits, recognition of syndromic autism in neurogenetic sydromes, advances in neuroimaging, and advances in animal models, both mutant mouse models and transgenic non human primate models...
April 18, 2018: International Review of Psychiatry
https://www.readbyqxmd.com/read/29667769/targeting-the-phosphatidylinositol-3-kinase-akt-mechanistic-target-of-rapamycin-signaling-pathway-in-b-lineage-acute-lymphoblastic-leukemia-an-update
#6
REVIEW
Carolina Simioni, Alberto M Martelli, Giorgio Zauli, Marco Vitale, James A McCubrey, Silvano Capitani, Luca M Neri
Despite considerable progress in treatment protocols, B-lineage acute lymphoblastic leukemia (B-ALL) displays a poor prognosis in about 15-20% of pediatric cases and about 60% of adult patients. In addition, life-long irreversible late effects from chemo- and radiation therapy, including secondary malignancies, are a growing problem for leukemia survivors. Targeted therapy holds promising perspectives for cancer treatment as it may be more effective and have fewer side effects than conventional therapies. The phosphatidylinositol 3-phosphate kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) signaling pathway is a key regulatory cascade which controls proliferation, survival and drug-resistance of cancer cells, and it is frequently upregulated in the different subtypes of B-ALL, where it plays important roles in the pathophysiology, maintenance and progression of the disease...
April 18, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29667732/anniversary-perspective-from-the-editor-in-chief
#7
EDITORIAL
Leonie Taams
No abstract text is available yet for this article.
May 2018: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/29667710/towards-sustainable-c-h-functionalization-reactions-the-emerging-role-of-bio-based-reaction-media
#8
Stefano Santoro, Assunta Marrocchi, Daniela Lanari, Lutz Ackermann, Luigi Vaccaro
In the last decade, transition-metal catalyzed C-H functionalization reactions have progressed enourmosly, becoming a useful tool in organic synthesis and a practibable alternative to well-established methodologies. Very recently, research efforts have also been devoted to developing more sustainable C-H functionalization protocols, in order to increase their applicability. One of the most promising approaches in this sense is represented by the substitution of common reaction media with bio-based solvents...
April 18, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29667699/lean-perspectives-a-case-for-implementing-parent-child-relational-problem-screening
#9
Bryson C Okeoma
The purpose of the current study was to make a case for instituting parent-child relational problem (PCRP) screening as a standard of care in pediatric inpatient psychiatric units due to increasing evidence that PCRP may be an underreported problem that affects more adolescents than currently realized. Adolescents who are admitted to the hospital for mood exacerbation, suicidal ideation, self-harm behavior, or behavioral escalation may improve and be discharged. However, these adolescents often are readmitted, which may be associated with parent-child relational factors...
April 17, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29667676/functional-inks-and-printing-of-two-dimensional-materials
#10
REVIEW
Guohua Hu, Joohoon Kang, Leonard W T Ng, Xiaoxi Zhu, Richard C T Howe, Christopher G Jones, Mark C Hersam, Tawfique Hasan
Graphene and related two-dimensional materials provide an ideal platform for next generation disruptive technologies and applications. Exploiting these solution-processed two-dimensional materials in printing can accelerate this development by allowing additive patterning on both rigid and conformable substrates for flexible device design and large-scale, high-speed, cost-effective manufacturing. In this review, we summarise the current progress on ink formulation of two-dimensional materials and the printable applications enabled by them...
April 18, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29667675/pre-programmed-self-assembly-of-polynuclear-clusters
#11
Takuya Shiga, Graham N Newton, Hiroki Oshio
This perspective reviews our recent efforts towards the self-assembly of polynuclear clusters with ditopic and tritopic multidentate ligands HL1 (2-phenyl-4,5-bis{6-(3,5-dimethylpyrazol-1-yl)pyrid-2-yl}-1H-imidazole) and H2L2 (2,6-bis-[5-(2-pyridinyl)-1H-pyrazole-3-yl]pyridine), both of which are planar and rigid molecules. HL1 was found to be an excellent support for tetranuclear [Fe4] complexes, [FeII4(L1)4](BF4)4 ([FeII4]) and [FeIII2FeII2(L1)4](BF4)6 ([FeIII2FeII2]). The homovalent system was found to exhibit multistep spin crossover (SCO), while the mixed-valence [FeIII2FeII2] complex shows wavelength-dependent tuneable light-induced excited spin state trapping (LIESST)...
April 18, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29667656/carbon-based-hybrid-nanogels-a-synergistic-nanoplatform-for-combined-biosensing-bioimaging-and-responsive-drug-delivery
#12
REVIEW
Hui Wang, Qianwang Chen, Shuiqin Zhou
Nanosized crosslinked polymer networks, named as nanogels, are playing an increasingly important role in a diverse range of applications by virtue of their porous structures, large surface area, good biocompatibility and responsiveness to internal and/or external chemico-physical stimuli. Recently, a variety of carbon nanomaterials, such as carbon quantum dots, graphene/graphene oxide nanosheets, fullerenes, carbon nanotubes, and nanodiamonds, have been embedded into responsive polymer nanogels, in order to integrate the unique electro-optical properties of carbon nanomaterials with the merits of nanogels into a single hybrid nanogel system for improvement of their applications in nanomedicine...
April 18, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29667480/the-human-gut-microbiota-metabolism-and-perspective-in-obesity
#13
Aline Corado Gomes, Christian Hoffmann, João Felipe Mota
The gut microbiota has been recognized as an important factor in the development of metabolic diseases such as obesity and is considered an endocrine organ involved in the maintenance of energy homeostasis and host immunity. Dysbiosis can change the functioning of the intestinal barrier and the gut-associated lymphoid tissues (GALT) by allowing the passage of structural components of bacteria, such as lipopolysaccharides (LPS), which activate inflammatory pathways that may contribute to the development of insulin resistance...
April 18, 2018: Gut Microbes
https://www.readbyqxmd.com/read/29667471/cost-effectiveness-analysis-of-suvorexant-for-the-treatment-of-japanese-elderly-patients-with-chronic-insnomnia-in-a-virtual-cohort
#14
Shinichi Nishimura, Mutsuhiro Nakao
AIMS: We assessed the cost effectiveness of the orexin receptor antagonist suvorexant against zolpidem, the most widely used hypnotic benzodiazepine receptor agonist in Japan. To this end, a model was used that factored in insomnia and the risk for hip fractures, which have devastating effects on the elderly. METHODS: Data were derived from published papers. The target population was a virtual cohort of elderly patients (≥65 years) with insomnia residing in Japan...
April 18, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29667464/end-user-evaluation-of-a-kneeling-wheelchair-with-on-the-fly-adjustable-seating-functions
#15
Johanne Mattie, Angie Wong, Danny Leland, Jaimie Borisoff
A "kneeling" ultralight wheelchair prototype has been developed that allows users to adjust seat position "on the fly" for different activities throughout the day. The wheelchair includes independent adjustment functions for rear seat height, front seat height ("kneeling") and backrest angle.  Aim: This work aimed to gather feedback about the wheelchair's functionality and performance through end user evaluation trials.  Methods: Eight manual wheelchair users evaluated the prototype Kneeling Wheelchair for a range of activities...
April 18, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29667459/asthma-management-in-new-york-city-schools-a-physical-education-teacher-perspective
#16
Qi Ying Li McClelland, Maria Ivanna Avalos, Marina Reznik
OBJECTIVE: Physical education (PE) teachers may be the first to assist students with asthma attacks during PE class. This study explores the PE teachers' perspectives on in-school asthma management and barriers to physical activity (PA) in children with asthma attending urban elementary schools. METHODS: We conducted qualitative semi-structured interviews with 16 PE teachers from 10 Bronx, NY elementary schools. Interviews were recorded, transcribed and independently coded...
April 18, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29667314/the-diary-of-a-nonagenarian-centenarian-woman-with-dementia-memory-loss-life-changes-and-community-care-in-japan
#17
Sayuri Suwa, Saori Otani, Mayuko Tsujimura, Kotoko Nogawa, Yoko Shiya
AIM: This study aimed to explore the experiences and thoughts of a nonagenarian-centenarian woman with dementia living alone, through detailed analysis of her unsolicited diary. DATA SOURCE: After receiving consent from Aki (a pseudonym), her family and caregivers, copies of her diaries, hand-written in Japanese, were provided for analysis. METHODS: The content of the diaries was broadly organized into themes and qualitative content analysis carried out for each theme along a sequential timeline...
April 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29667308/diagnosis-and-management-of-giant-cell-arteritis-an-asia-pacific-perspective
#18
Jem V Ninan, Susan Lester, Catherine L Hill
No abstract text is available yet for this article.
April 17, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29667255/nonvolatile-memory-materials-for-neuromorphic-intelligent-machines
#19
REVIEW
Doo Seok Jeong, Cheol Seong Hwang
Recent progress in deep learning extends the capability of artificial intelligence to various practical tasks, making the deep neural network (DNN) an extremely versatile hypothesis. While such DNN is virtually built on contemporary data centers of the von Neumann architecture, physical (in part) DNN of non-von Neumann architecture, also known as neuromorphic computing, can remarkably improve learning and inference efficiency. Particularly, resistance-based nonvolatile random access memory (NVRAM) highlights its handy and efficient application to the multiply-accumulate (MAC) operation in an analog manner...
April 18, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29667210/pastoral-power-and-the-promotion-of-self-care
#20
Lorelei Jones
In many countries government policy is becoming increasingly reliant on citizens taking greater responsibility for their health and wellbeing and limiting their consumption of public services. In this paper I develop Foucauldian perspectives on the work required to create and maintain responsibilised subjects, focusing on the role of 'pastors' - specialists, experts and therapists who promote desirable subjectivities (Waring and Latif ). Drawing from ethnographic research, I consider how government policies for the promotion of self-care within the English healthcare system not only place increased emphasis on patients taking responsibility for their own health and wellbeing, but also seek to constitute new pastoral subjectivities as responsible for conducting the conduct of patients...
April 17, 2018: Sociology of Health & Illness
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