keyword
MENU ▼
Read by QxMD icon Read
search

Intensif care

keyword
https://www.readbyqxmd.com/read/29672887/young-age-is-associated-with-increased-rates-of-residual-recurrent-pediatric-differentiated-thyroid-carcinoma
#1
Sarah Hampson, Derek Stephens, Jonathan D Wasserman
OBJECTIVE: Differentiated thyroid carcinoma is rare in young children. There are conflicting data as to whether disease in this age group differs from that in adolescents and specifically, if it is more aggressive. Current practice guidelines do not differentiate treatment between these groups, but speculate that differences may exist. We sought to compare clinical features, treatment and outcomes between children (<12 years) and adolescents (12-18 years) with thyroid nodules and thyroid malignancy over a 20 year period...
April 19, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29615967/therapeutic-inertia-in-the-new-landscape-of-multiple-sclerosis-care
#2
Gustavo Saposnik, Xavier Montalban
The landscape of multiple sclerosis (MS) treatment is constantly changing. Significant heterogeneity exists in the efficacy and risks associated with these therapies. Therefore, clinicians have the challenge to tailor treatment based on several factors (disease activity level, risk of progression, individual patient preferences and characteristics, personal expertise, etc.), to identify the optimal balance between safety and efficacy. However, most clinicians have limited education in decision-making and formal training in risk management...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29579770/acute-cellular-rejection-is-it-still-relevant
#3
Angela Koutsokera, Liran Levy, Prodipto Pal, Ani Orchanian-Cheff, Tereza Martinu
Despite significant progress in the field of transplant immunology, acute cellular rejection (ACR) remains a very frequent complication after lung transplantation (LTx), with almost 30% of LTx recipients experiencing at least one episode of treated ACR during the first year of follow-up. Most episodes respond to the first-line immunosuppressive treatment and are rarely a direct cause of death. However, the association of ACR with later adverse outcomes, such as chronic lung allograft dysfunction, bronchial stricture, and infectious complications associated with the intensification of immunosuppression, negatively impacts long-term survival...
April 2018: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29569380/modeling-missed-care-implications-for-evidence-based-practice
#4
Ian Blackman, Che Yee Lye, I Gusti Ngurah Darmawan, Julie Henderson, Tracey Giles, Eileen Willis, Luisa Toffoli, Lily Xiao, Claire Verrall
BACKGROUND: There is a growing nursing literature that views missed care as an inevitable consequence of work intensification associated with the rationing of nursing and material resources available to deliver care. Global studies recognize that missed care is now ubiquitous, although studies tend to be conducted in one region, rather than nationwide. This study seeks to understand the Australian context of missed care. AIMS: To explore self-reported reasons for missed care and to identify the main factors for predicting missed care within a sample of Australian nurses and midwives working in public and private hospitals in New South Wales, Victoria, Tasmania, and South Australia...
March 23, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29535235/patient-centered-guidelines-for-geriatric-diabetes-care-potential-missed-opportunities-to-avoid-harm
#5
Ellen M McCreedy, Robert L Kane, Sarah E Gollust, Nathan D Shippee, Kirby D Clark
BACKGROUND: Clinicians strive to deliver individualized, patient-centered care. However, these intentions are understudied. This research explores how patient characteristics associated with an high risk-to-benefit ratio with hypoglycemia medications affect decision making by primary care clinicians. METHODS: Using a vignette-based survey, we queried primary care clinicians on their intended management of geriatric patients with diabetes. The patients' ages, disease durations, and comorbidities were systematically varied...
March 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29530905/feasibility-of-a-blended-group-treatment-bgt-for-major-depression-uncontrolled-interventional-study-in-a-university-setting
#6
Raphael Schuster, Isabelle Fichtenbauer, Verena Maria Sparr, Thomas Berger, Anton-Rupert Laireiter
OBJECTIVE: This study investigated the feasibility of a novel blended (face-to-face and computer-based) group intervention for the reduction of depressive symptoms in major depression. DESIGN: Patient-centred uncontrolled interventional study. SETTING: University setting in a general community sample. A multimodal recruitment strategy (public health centres and public areas) was applied. PARTICIPANTS: Based on independent interviews, 26 participants, diagnosed with major depressive disorder (81% female; 23% comorbidity >1 and 23% comorbidity >2), entered treatment...
March 12, 2018: BMJ Open
https://www.readbyqxmd.com/read/29522072/association-of-survival-with-shorter-time-to-radiation-therapy-after-surgery-for-us-patients-with-head-and-neck-cancer
#7
Jeremy P Harris, Michelle M Chen, Ryan K Orosco, Davud Sirjani, Vasu Divi, Wendy Hara
Importance: Shortening the time from surgery to the start of radiation (TS-RT) is a consideration for physicians and patients. Although the National Comprehensive Cancer Network recommends radiation to start within 6 weeks, a survival benefit with this metric remains controversial. Objective: To determine the association of delayed TS-RT with overall survival (OS) using a large cancer registry. Design, Setting, and Participants: In this observational cohort study, 25 216 patients with nonmetastatic stages III to IV head and neck cancer were identified from the National Cancer Database (NCDB)...
March 8, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29512797/epidemiological-clinical-and-pronostic-aspects-of-multiple-myeloma-eligible-for-therapeutic-intensification-followed-by-autologous-hematopoietic-stem-cell-in-the-algerian-west-report-of-147-cases
#8
Latifa Mohammadi, Noria Harir, Mohamed Brahimi, Soraya Moulessehoul, Mohamed Amine Bekadja
BACKGROUND: Multiple Myeloma (MM) represent about 1 to 2% of cancers and 15% of all hematological malignancies. It is characterized by malignant proliferation of plasmocytes in bone marrow and an excess of secreted monoclonal immunoglobulins (Ig) Objective: Describe the epidemiological, clinical, biological and prognosis of patients with MM treated with autologous peripheral hematopoietic stem cell transplantation (APHSCT) in the Algerian West. METHODS: It is a retrospective descriptive study covering all MM patients treated with APHSCT over a period of 7 years (2008-2015) at service of Haematology and Cell Therapy of the EHU "1er November 1954 of Oran, Algeria...
June 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29512219/treatment-as-prevention-for-hepatitis-c-trap-hep-c-a-nationwide-elimination-programme-in-iceland-using-direct-acting-antiviral-agents
#9
S Olafsson, T Tyrfingsson, V Runarsdottir, O M Bergmann, I Hansdottir, E S Björnsson, B Johannsson, B Sigurdardottir, R H Fridriksdottir, A Löve, M Hellard, T J Löve, T Gudnason, M Heimisdottir, M Gottfredsson
A nationwide programme for the treatment of all patients infected with hepatitis C virus (HCV) was launched in Iceland in January 2016. By providing universal access to direct-acting antiviral agents to the entire patient population, the two key aims of the project were to (i) offer a cure to patients and thus reduce the long-term sequelae of chronic hepatitis C, and (ii) to reduce domestic incidence of HCV in the population by 80% prior to the WHO goal of HCV elimination by the year 2030. An important part of the programme is that vast majority of cases will be treated within 36 months from the launch of the project, during 2016-2018...
March 7, 2018: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29479760/what-nurses-and-midwives-want-findings-from-the-national-survey-on-workplace-climate-and-well-being
#10
Peter J Holland, Tse Leng Tham, Fenella J Gill
AIM: A discussion of the findings from a nationwide study of workplace and well-being issues of Australian nurses and midwives. BACKGROUND: Current discourse only provides a fragmented understanding of a multifaceted nature of working conditions and well-being, necessitating a more holistic investigation to identify critical workplace issues within these professions. DESIGN: Discussion paper. DATA SOURCES: A national survey conducted in July 2016 involving Australian Nursing and Midwifery Federation members...
February 26, 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29468559/15-years-of-experience-with-biphasic-insulin-aspart-30-in-type-2-diabetes
#11
REVIEW
Andreas Liebl, Viswanathan Mohan, Wenying Yang, Krzysztof Strojek, Sultan Linjawi
Since clinical experience with biphasic insulin aspart 30 (BIAsp 30) in type 2 diabetes mellitus (T2DM) was reviewed in 2012 after 10 years of use worldwide, additional studies have been published that highlight new aspects, including use in real-world populations. Evidence from 35 new studies confirms and builds upon previous work indicating that BIAsp 30 continues to have pharmacodynamic and clinical advantages over biphasic human insulin (BHI 30), including in real-world practice with unselected populations of patients...
February 21, 2018: Drugs in R&D
https://www.readbyqxmd.com/read/29466263/work-intensification-and-quality-assurance-missed-nursing-care
#12
Eileen Willis, Clare Harvey, Shona Thompson, Maria Pearson, Alannah Meyer
This article examines nurses' commentaries from a survey conducted in New Zealand that studied contradictions between quality assurance and work intensification in nursing care. Nurse managers were blamed for either avoiding or not recognizing work intensification affecting quality care delivery. However, the data illustrate key structural issues resulting in missed care that impact on patient safety, rather than a problem directly attributable to managers. Until these structural issues are addressed, missed care and adverse events will continue to affect the quality of care...
April 2018: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/29402869/treatment-of-hypertension-in-renal-transplant-recipients-in-four-independent-cross-sectional-analyses
#13
Izabella Kuźmiuk-Glembin, Dorota Adrych, Leszek Tylicki, Zbigniew Heleniak, Hanna Garnier, Jakub Wiśniewski, Przemysław Rutkowski, Bolesław Rutkowski, Alicja Dębska-Ślizień
BACKGROUND/AIMS: This retrospective study analysed hypertension management and adherence to blood pressure (BP) targets among renal transplant recipients (RTRs) under specialized care in the Outpatient Transplantation Unit in the Department of Nephrology, Transplantology and Internal Medicine at Gdansk University Hospital. METHODS: Medical records of 101, 316, 639 and 818 RTRs diagnosed with hypertension, who received outpatient care in 2001, 2006, 2011 and 2014, respectively were analysed in four independent cross-sectional surveys...
January 24, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29385955/psychiatric-case-review-and-treatment-intensification-in-collaborative-care-management-for-depression-in-primary-care
#14
Nathaniel A Sowa, Philip Jeng, Amy M Bauer, Joseph M Cerimele, Jürgen Unützer, Yuhua Bao, Lydia Chwastiak
OBJECTIVE: This study examined whether psychiatric case review was associated with depression medication modification in a large implementation program of collaborative care for depression in safety-net primary care clinics. METHODS: Registry data were examined from an implementation of the collaborative care model in Washington State. A total of 14,960 adults from 178 primary care clinics who initiated care between January 1, 2008, and September 30, 2014, and who had a baseline Patient Health Questionnaire-9 (PHQ-9) score of 10 or higher were included...
February 1, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29361094/a-mobile-infliximab-dosing-calculator-for-therapy-optimization-in-inflammatory-bowel-disease
#15
Travis Piester, Adam Frymoyer, Megan Christofferson, Helen Yu, Dorsey Bass, K T Park
Background: Inadequate infliximab (IFX) drug exposure remains a clinical challenge and leads to high loss of response rates and therapy failure in inflammatory bowel disease (IBD). We aimed to determine the feasibility and pilot effectiveness of a novel, web-based, mobile IFX dosing calculator (mIDC) for therapy optimization. Methods: We developed an mIDC leveraging the known clinical variables of C-reative protein (CRP), albumin, patient's weight, disease activity indices, calprotectin, drug trough levels, and antibodies to IFX that significantly affect pharmacokinetics and/or outcomes...
January 18, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29358503/beyond-concurrent-chemoradiation-the-emerging-role-of-pd-1-pd-l1-inhibitors-in-stage-iii-lung-cancer
#16
Neal S McCall, Adam P Dicker, Bo Lu
Concurrent chemoradiation (cCRT) with platinum-based chemotherapy is standard-of-care therapy for patients with stage III unresectable non-small cell lung cancer (NSCLC). Although cCRT is potentially curative, 5-year overall survival has hovered around 20%, despite extensive efforts to improve outcomes with increasing doses of conformal radiation and intensification of systemic therapy with either induction or consolidation chemotherapy. PD-1/PD-L1 immune checkpoint inhibitors have demonstrated unprecedented efficacy in patients with stage IV NSCLC...
March 15, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29341850/clinical-inertia-in-a-randomized-trial-of-telemedicine-based-chronic-disease-management-lessons-learned
#17
Anna Beth Barton, Daniel E Okorodudu, Hayden B Bosworth, Matthew J Crowley
BACKGROUND: Treatment nonadherence and clinical inertia perpetuate poor cardiovascular disease (CVD) risk factor control. Telemedicine interventions may counter both treatment nonadherence and clinical inertia. INTRODUCTION: We explored why a telemedicine intervention designed to reduce treatment nonadherence and clinical inertia did not improve CVD risk factor control, despite enhancing treatment adherence versus usual care. METHODS: In this analysis of a randomized trial, we studied recipients of the 12-month telemedicine intervention...
January 17, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29316149/measure-accurately-act-rapidly-and-partner-with-patients-map-improves-hypertension-control-in-medically-underserved-patients-care-coordination-institute-and-american-medical-association-hypertension-control-project-pilot-study-results
#18
Robert B Hanlin, Irfan M Asif, Gregory Wozniak, Susan E Sutherland, Bijal Shah, Jianing Yang, Robert A Davis, Sean T Bryan, Michael Rakotz, Brent M Egan
Measure Accurately, Act Rapidly, and Partner With Patients (MAP) is an evidence-based protocol implemented to improve hypertension control in a clinic for underserved patients (49.9% Medicaid and 50.2% black). Patients with hypertension seen during the year before intervention and with at least one visit during the 6-month intervention (N = 714) were included. If initial attended blood pressure (BP; standard aneroid manometer) was ≥140/≥90 mm Hg, unattended automated office BP was measured in triplicate and averaged (Measure Accurately) using an Omron HEM-907XL...
January 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29230931/temporal-changes-in-glycaemic-thresholds-for-treatment-intensification-in-type-2-diabetes-in-an-urban-australian-setting-the-fremantle-diabetes-study
#19
Timothy M E Davis, Stephen A P Chubb, Bradley H Curtis, Helen Barraclough, Wendy A Davis
BACKGROUND: Pharmacotherapy and supportive care for diabetes in Australia are improving, with potential beneficial effects on therapeutic procrastination. AIMS: To determine whether glycaemic thresholds for therapeutic intensification in type 2 diabetes changed over the 15 years between Phases of the community-based Fremantle Diabetes Study (FDS). METHODS: We studied 531 Phase 1 participants (mean age 62.4 years, 54.2% males, median diabetes duration 3...
December 12, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29222268/tailoring-front-line-therapy-in-diffuse-large-b-cell-lymphoma-who-should-we-treat-differently
#20
REVIEW
Andrew Davies
Although there have been significant insights into the biology of diffuse large B-cell lymphoma (DLBCL) over recent years, progress in our therapeutic approach has been disappointing over the same timeframe. This is not for want of trying. In 2017, R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) remains the "gold standard," despite all of our insights into cell-of-origin and other subgroups. We have traditionally used clinical risk factors to tailor our therapies and have tested intensification of chemotherapy with little success...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
keyword
keyword
42512
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"