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PET-CT endocarditis

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https://www.readbyqxmd.com/read/28807509/-18-f-fdg-pet-ct-angiography-in-the-diagnosis-of-infective-endocarditis-and-cardiac-device-infection-in-adult-patients-with-congenital-heart-disease-and-prosthetic-material
#1
María N Pizzi, L Dos-Subirà, Albert Roque, Nuria Fernández-Hidalgo, Hug Cuéllar-Calabria, Antonia Pijuan Domènech, María T Gonzàlez-Alujas, M T Subirana-Domènech, B Miranda-Barrio, Ignacio Ferreira-González, Juan J González-López, Albert Igual, Olga Maisterra-Santos, David García-Dorado, Joan Castell-Conesa, Benito Almirante, Manuel Escobar Amores, Pilar Tornos, Santiago Aguadé-Bruix
OBJECTIVES: Infective endocarditis (IE) and cardiac device infection (CDI) are a major complication in the growing number of patients with congenital heart disease (CHD) reaching adulthood. We aimed to evaluate the added value of (18)F-FDG-PET/CT angiography (PET/CTA) in the diagnosis of IE-CDI in adults with CHD and intravascular or intracardiac prosthetic material, in whom echocardiography (ECHO) and modified Duke Criteria (DC) have limitations because of the patients' complex anatomy...
August 9, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28672417/-infections-as-a-cause-of-unexplained-fever
#2
REVIEW
Bernd Salzberger, Gabriele Birkenfeld, Michael Iberer, Florian Hitzenbichler
Fever of unexplained (or unknown) origin (FUO) remains a relevant clinical problem even with modern diagnostic methods. In addition to the classical definition, new categories of FUO describe different clinical situations: nosocomial FUO, FUO in neutropenic/immundeficient patients and FUO in patients with HIV-infection. The new categories are defined by much shorter duration of fever, i. e. mostly three days. Each category of FUO shows a different spectrum of infectious diseases. Often, subacute bacterial endocarditis is very difficult to verify...
July 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28585029/another-potential-step-to-improve-prosthetic-heart-valve-endocarditis-imaging-with-18-f-fdg-pet-ct
#3
EDITORIAL
Thomas H Schindler
No abstract text is available yet for this article.
June 5, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28585026/standardized-uptake-values-in-fdg-pet-ct-for-prosthetic-heart-valve-endocarditis-a-call-for-standardization
#4
Asbjørn M Scholtens, Laurens E Swart, Henryk J Te Kolste, Ricardo P J Budde, Marnix G E H Lam, Hein J Verberne
BACKGROUND: The significance of and threshold values for the standardized uptake value (SUV) in FDG PET/CT to diagnose prosthetic heart valve (PHV) endocarditis (PVE) are unclear at present. METHODS: A literature search was performed in the PubMed and EMBASE medical databases, comprising the following terms: (FDG OR *fluorode* OR *fluoro-de*) AND (endocarditis OR prosthetic heart valve OR valve replacement). Studies reporting SUVs correlated to the diagnosis of PVE were selected for analysis...
June 5, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28560560/fdg-pet-ct-in-prosthetic-heart-valve-endocarditis-there-is-no-need-to-wait
#5
EDITORIAL
A M Scholtens, R P J Budde, M G E H Lam, H J Verberne
No abstract text is available yet for this article.
May 30, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28549959/pet-scan-and-duplex-ultrasound-for-the-detection-of-arterial-complications-of-bacterial-endocarditis
#6
Carine Boulon, Noëlle Bernard, Fabrice Bonnet, Joël Constans
18F-FDG-PET may be useful to diagnose complications of endocarditis in difficult cases. We report the case of a young patient who had endocarditis and a painful leg. FDG PET/CT showed hypermetabolism in the leg and duplex ultrasound suggested an inflammatory aneurysm at the site of the hypermetabolism. The combination of FDG-PET/CT and duplex ultrasound is useful to diagnose mycotic aneurysm in the setting of bacterial endocarditis.
May 23, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28546336/the-value-of-18-f-fdg-pet-ct-in-diagnosis-and-during-follow-up-in-273-patients-with-chronic-q-fever
#7
Ilse Kouijzer, Linda Kampschreur, Peter Wever, Corneline Hoekstra, Marjo van Kasteren, Monique de Jager-Leclercq, Marrigje Nabuurs-Franssen, Marjolijn Wegdam-Blans, Heidi Ammerlaan, Jacqueline Buijs, Lioe-Fee de Geus-Oei, Wim Oyen, Chantal Bleeker-Rovers
In 1-5% of all acute Q fever infections, chronic Q fever develops, mostly manifesting as endocarditis, infected aneurysms, or infected vascular prostheses. In this study, we investigated the diagnostic value of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG-PET/CT) in chronic Q fever at diagnosis and during follow-up. Methods: All Dutch adult patients suspected of chronic Q fever who were diagnosed since 2007 were retrospectively included until March 2015 when at least one (18)F-FDG-PET/CT was performed...
May 25, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28491879/listeria-endocarditis-a-diagnostic-challenge
#8
Wilhelmina J A R M Valckx, Suzanne P M Lutgens, Hortence E Haerkens-Arends, Peter C Barneveld, Jaap J Beutler, Ellen K Hoogeveen
A 74-year-old hemodialysis patient with a history of an atrial septum defect closure, coronary bypass surgery, and a St. Jude aortic prosthetic valve was diagnosed with pneumonia and volume overload. Blood cultures were positive for Listeria monocytogenes, and amoxicillin was given for 2 weeks. Immediately after discontinuation of amoxicillin, fever relapsed. Transthoracic and transesophageal echocardiography showed no sign of endocarditis. Given the fever relapse and 3 positive minor Duke criteria, an (18)F-FDG PET-CT scan ((18)F-fluorodeoxyglucose-positron emission tomography-computed tomography) scan was performed...
April 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28474192/dual-time-point-fdg-pet-ct-imaging-in-prosthetic-heart-valve-endocarditis
#9
A M Scholtens, L E Swart, H J Verberne, R P J Budde, M G E H Lam
PURPOSE: FDG PET/CT has been of increasing interest in the diagnostic workup of prosthetic heart valve endocarditis (PVE). Some reports advocate later imaging time points to improve the diagnostic accuracy for PVE. In this study, we compared standard and late FDG PET/CT images in patients with a clinical suspicion of PVE. MATERIALS AND METHODS: Fourteen scans in 13 patients referred for FDG PET/CT for suspicion of PVE performed at standard (60 min post injection) and late (150 min post injection) time points were scored based on visual interpretation and semi-quantitatively with SUVmax and target-to-background ratio (TBR, defined as [SUVmax valve/SUVmean blood pool])...
May 4, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28330738/graft-infection-after-a-bentall-procedure-a-case-series-and-systematic-review-of-the-literature
#10
I Machelart, C Greib, G Wirth, F Camou, N Issa, J F Viallard, J L Pellegrin, E Lazaro
INTRODUCTION: The Bentall procedure is a cardiac surgery involving graft replacement of the aortic valve, aortic root and ascending aorta. Graft infection after Bentall's procedure (BGI) is infrequent but severe, and often difficult to diagnose and treat. PATIENTS AND METHODS: A retrospective cohort study was performed using the Bordeaux endocarditis database of adult patients admitted to the Bordeaux University Medical Hospital for BGI between 2008 and 2014. Published case reports were identified in the literature...
March 7, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28326754/supporting-imaging-modalities-for-improving-diagnosis-of-prosthesis-endocarditis-preliminary-results-of-a-single-center-experience-with-18f-fdg-pet-ct
#11
Anna Kokalova, Angelo M Dell'aquila, Nemanja Avramovic, Sven Martens, Christian Wenning, Jürgen R Sindermann
BACKGROUND: The aim of the current study was to evaluate the role of PET-CT in the diagnosis of prosthetic valve endocarditis (PVE). METHODS: This is a single-center study including 13 PET/CT examinations performed between February 2009 and March 2016 in 13 patients (76.9% men, mean age 68.1 years, IQR 11.1) because of suspect of PVE. Median interval time between first operation and PET/CT examination was 19.02 months (IQR 85.5). Final diagnosis was made according to pathological criteria (histological and microbiological) of the Duke classification...
August 2017: Minerva Medica
https://www.readbyqxmd.com/read/28298285/characterization-of-18-f-fluorodeoxyglucose-uptake-pattern-in-noninfected-prosthetic-heart-valves
#12
Cédric Mathieu, Nidaa Mikaïl, Khadija Benali, Bernard Iung, Xavier Duval, Patrick Nataf, Guillaume Jondeau, Fabien Hyafil, Dominique Le Guludec, François Rouzet
BACKGROUND: (18)F-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has been recently acknowledged as a diagnostic tool for prosthetic valve endocarditis, but its specificity is limited by uptake on noninfected valves. The objective of this study was to outline the main features of FDG uptake on PET/CT in patients with noninfected prosthetic heart valve (PHV). METHODS AND RESULTS: Our institution's PET/CT database was reviewed to identify patients with PHV, excluding those suspected of infection or who had received antibiotic treatment...
March 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28298163/pet-ct-added-to-duke-criteria-facilitates-diagnosis-and-monitoring-of-long-term-suppressive-therapy-of-prosthetic-endocarditis
#13
Pedro Puerta-Alcalde, Guillermo Cuervo, Antonella F Simonetti, Laura Gracia-Sánchez, Daniel Ortiz, Carolina Garcia-Vidal
No abstract text is available yet for this article.
March 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28250859/-18-f-fdg-pet-ct-for-the-diagnosis-of-malignant-and-infectious-complications-after-solid-organ-transplantation
#14
Nastassja Muller, Romain Kessler, Sophie Caillard, Eric Epailly, Fabrice Hubelé, Céline Heimburger, Izzie-Jacques Namer, Raoul Herbrecht, Cyrille Blondet, Alessio Imperiale
PURPOSE: Infection and malignancy represent two common complications after solid organ transplantation, which are often characterized by poorly specific clinical symptomatology. Herein, we have evaluated the role of (18)F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT) in this clinical setting. METHODS: Fifty-eight consecutive patients who underwent FDG PET/CT after kidney, lung or heart transplantation were included in this retrospective analysis...
March 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28185172/-18-f-fdg-pet-ct-angiography-for-the-diagnosis-of-infective-endocarditis
#15
REVIEW
A Roque, M N Pizzi, H Cuéllar-Calàbria, S Aguadé-Bruix
PURPOSE OF REVIEW: This article reviews the current imaging role of (18)F-fluordeoxyglucose positron emission computed tomography ((18)F-FDG-PET/CT) combined with cardiac CT angiography (CTA) in infective endocarditis and discusses the strengths and limitations of this technique. RECENT FINDINGS: The diagnosis of infective endocarditis affecting prosthetic valves and intracardiac devices is challenging because echocardiography and, therefore, the modified Duke criteria have well-recognized limitations in this clinical scenario...
February 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28050751/clinical-utility-of-18-f-fdg-positron-emission-tomography-computed-tomography-scan-vs-99m-tc-hmpao-white-blood-cell-single-photon-emission-computed-tomography-in-extra-cardiac-work-up-of-infective-endocarditis
#16
Trine K Lauridsen, Kasper K Iversen, Nikolaj Ihlemann, Philip Hasbak, Annika Loft, Anne K Berthelsen, Anders Dahl, Danijela Dejanovic, Elisabeth Albrecht-Beste, Jann Mortensen, Andreas Kjær, Henning Bundgaard, Niels Eske Bruun
The extra-cardiac work-up in infective endocarditis (IE) comprises a search for primary and secondary infective foci. Whether (18)FDG-PET/CT or WBC-SPECT/CT is superior in detection of clinically relevant extra-cardiac manifestations in IE is unexplored. The objectives of this study were to identify the numbers of positive findings detected by each imaging modality, to evaluate the clinical relevance of these findings and to define the reproducibility for extra-cardiac foci in patients with definite IE. Each modality was evaluated for numbers and location of positive extra-cardiac foci in patients with definite IE...
January 3, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27997426/subacute-cortical-infarct-showing-uptake-on-68ga-psma-pet-ct
#17
Mico Chan, Edward Hsiao
Ga prostate-specific membrane antigen (PSMA) PET/CT is increasingly used to evaluate extent of disease in prostate carcinoma. We present a case of subacute cortical cerebral infarct showing focal uptake on PSMA PET/CT. It is an important potential cause of false-positive uptake in this imaging cohort. The patient is an 85-year-old man with a background of nonbacterial thrombotic endocarditis and previous cerebrovascular events. He was referred for PSMA PET/CT for staging of high-risk prostate cancer.
February 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27822623/-esc-and-aha-guidelines-2015-on-endocarditis-in-competition-or-synchrony
#18
COMPARATIVE STUDY
Bernhard Maisch
In the 2015 guidelines of the European Society of Cardiology (ESC) and the American Heart Association (AHA) on infective endocarditis, the diagnostics are based on the modified Duke criteria. The diagnosis can be confirmed by a combination of micro-organisms demonstrated in culture or in situ, with the detection of valvular lesions or abscess formation by an imaging modality using echocardiography, positron emission tomography computed tomography (PET/CT), cardio-CT or nuclear medical methods. The management should be further improved by an interdisciplinary endocarditis team in a specifically designated reference center...
December 2016: Herz
https://www.readbyqxmd.com/read/27761883/cross-sectional-imaging-of-aortic-infections
#19
REVIEW
D J Murphy, A R Keraliya, M D Agrawal, A Aghayev, M L Steigner
Aortic infections are uncommon clinical entities, but are associated with high rates of morbidity and mortality. In this review, we focus on the cross-sectional imaging appearance of aortic infections, including aortic valve endocarditis, pyogenic aortitis, mycotic aneurysm and aortic graft infections, with an emphasis on CT, MRI and PET/CT appearance. Teaching Points • Aortic infections are associated with high morbidity and mortality. • CT, MRI and FDG PET/CT play complementary roles in aortic infection imaging...
December 2016: Insights Into Imaging
https://www.readbyqxmd.com/read/27746163/diagnostic-value-of-imaging-in-infective-endocarditis-a-systematic-review
#20
REVIEW
Anna Gomes, Andor W J M Glaudemans, Daan J Touw, Joost P van Melle, Tineke P Willems, Alexander H Maass, Ehsan Natour, Niek H J Prakken, Ronald J H Borra, Peter Paul van Geel, Riemer H J A Slart, Sander van Assen, Bhanu Sinha
Sensitivity and specificity of the modified Duke criteria for native valve endocarditis are both suboptimal, at approximately 80%. Diagnostic accuracy for intracardiac prosthetic material-related infection is even lower. Non-invasive imaging modalities could potentially improve diagnosis of infective endocarditis; however, their diagnostic value is unclear. We did a systematic literature review to critically appraise the evidence for the diagnostic performance of these imaging modalities, according to PRISMA and GRADE criteria...
January 2017: Lancet Infectious Diseases
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