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iugr and perinatal outcome

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https://www.readbyqxmd.com/read/29436080/fetoscopic-laser-photocoagulation-for-twin-twin-transfusion-syndrome
#1
Haruhiko Sago, Keisuke Ishii, Rika Sugibayashi, Katsusuke Ozawa, Masahiro Sumie, Seiji Wada
The aim of this study was to review fetoscopic laser photocoagulation (FLP), which ablates placental vascular anastomoses to treat twin-twin transfusion syndrome (TTTS). A review of studies reporting on the procedures, outcomes, complications and nonconventional applications of FLP for TTTS was conducted. FLP has been established as the primary treatment for monochorionic twin pregnancy associated with TTTS at 16-26 weeks. FLP is the only therapy that directly addresses the underlying pathophysiology. The recent technique modification of FLP, referred to as the 'Solomon technique', induces selective coagulation to connect the anastomoses ablation sites and has been introduced to reduce residual anastomoses...
February 13, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29413487/maternal-protein-restriction-during-lactation-induces-early-and-lasting-plasma-metabolomic-and-hepatic-lipidomic-signatures-of-the-offspring-in-a-rodent-programming-model
#2
Aurore Martin Agnoux, Angélina El Ghaziri, Thomas Moyon, Anthony Pagniez, Agnès David, Gilles Simard, Patricia Parnet, El Mostafa Qannari, Dominique Darmaun, Jean-Philippe Antignac, Marie-Cécile Alexandre-Gouabau
Perinatal undernutrition affects not only fetal and neonatal growth but also adult health outcome, as suggested by the metabolic imprinting concept. However, the exact mechanisms underlying offspring metabolic adaptations are not yet fully understood. Specifically, it remains unclear whether the gestation or the lactation is the more vulnerable period to modify offspring metabolic flexibility. We investigated in a rodent model of intrauterine growth restriction (IUGR) induced by maternal protein restriction (R) during gestation which time window of maternal undernutrition (gestation, lactation or gestation-lactation) has more impact on the male offspring metabolomics phenotype...
December 10, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29411344/maternal-and-perinatal-outcomes-of-dichorionic-diamniotic-twin-pregnancies-diagnosed-with-vanishing-twin-syndrome-a-retrospective-analysis-from-a-single-clinical-center
#3
Hakan Timur, Rifat Taner Aksoy, Aytekin Tokmak, Burcu Timur, Bugra Coskun, Dilek Uygur, Nuri Danisman
OBJECTIVES: Multiple pregnancies are known to be associated with adverse maternal and perinatal complications. How-ever, data regarding the outcomes of spontaneously reduced twin pregnancies are limited. In the current study we aimed to evaluate the consequences of the vanishing twin syndrome (VTS) in dichorionic diamniotic twin pregnancies for both mother and baby in our perinatal center. MATERIAL AND METHODS: A total of 711 pregnancies were included into the study...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29400413/pregnancy-and-delivery-outcomes-from-patients-with-repaired-anomalous-origin-of-the-left-coronary-artery-from-the-pulmonary-artery
#4
Miki Kanoh, Kei Inai, Tokuko Shinohara, Eriko Shimada, Mikiko Shimizu, Hirofumi Tomimatsu, Masaki Ogawa, Toshio Nakanishi
AIM: We investigated the clinical courses before and during pregnancy and after delivery in patients with repaired anomalous origin of the left coronary artery from the pulmonary artery to determine the impact of the hemodynamic changes and cardiac function on the selection of the appropriate mode of delivery. METHODS: Six patients who underwent coronary artery reimplantation delivered 10 infants. We scrutinized the patients' hemodynamic changes on echocardiographs and the plasma brain natriuretic peptide levels before and during pregnancy and after delivery, the perinatal outcomes and maternal and fetal events...
February 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29304392/aspirin-non-responsiveness-in-pregnant-women-at-high-risk-of-pre-eclampsia
#5
Kate Navaratnam, Ana Alfirevic, Andrea Jorgensen, Zarko Alfirevic
OBJECTIVES: Low-dose aspirin is recommended for prevention of pre-eclampsia in high-risk pregnant women. Current doses provide a conservative risk reduction and some individuals demonstrate 'aspirin non-responsiveness', with insufficient antiplatelet effects. We aimed to determine if aspirin non-responsiveness could be identified in women at high risk of pre-eclampsia and assess for potential associations with placentally-mediated adverse outcomes. STUDY DESIGN: Prospective cohort study...
February 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29286910/selective-iugr-in-dichorionic-twins-what-can-doppler-assessment-and-growth-discordancy-say-about-neonatal-outcomes
#6
Paola Algeri, Matteo Frigerio, Maria Lamanna, Petya Vitanova Petrova, Sabrina Cozzolino, Maddalena Incerti, Salvatore Andrea Mastrolia, Nadia Roncaglia, Patrizia Vergani
OBJECTIVE: The aim of the present study was to assess, in a population of dichorionic twin pregnancies with selective growth restriction, the effect of inter-twin differences by use of Doppler velocimetry and fetal growth discordancy on perinatal outcomes. METHODS: This was a retrospective study including dichorionic twin pregnancies from January 2008 to December 2015 at the Department of Obstetrics and Gynecology of Fondazione MBBM. Only dichorionic twin pregnancies affected by selective intrauterine growth restriction (IUGR) delivering at ≥24 weeks were included in the study...
December 29, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29274932/adverse-perinatal-conditions-associated-with-prenatally-detected-fetal-echogenic-bowel-in-nova-scotia
#7
Rachelle Findley, Victoria M Allen, Jo-Ann K Brock
OBJECTIVE: This study sought to estimate the association of adverse perinatal outcomes with pregnancies complicated by fetal echogenic bowel. METHODS: Data for pregnancies complicated with echogenic bowel identified in the second trimester were derived from the tertiary referral IWK Health Centre (Halifax, NS) Viewpoint Ultrasound Database augmented by medical chart review. The study was undertaken between 2003 and 2014. Rates of positive cytomegalovirus and toxoplasmosis infection were determined using maternal serology and amniocentesis results...
December 21, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29216559/pregnancy-outcomes-and-ethanol-cook-stove-intervention-a-randomized-controlled-trial-in-ibadan-nigeria
#8
Donee A Alexander, Amanda Northcross, Theodore Karrison, Oludare Morhasson-Bello, Nathaniel Wilson, Omolola M Atalabi, Anindita Dutta, Damilola Adu, Tope Ibigbami, John Olamijulo, Dayo Adepoju, Oladosu Ojengbede, Christopher O Olopade
BACKGROUND: Household air pollution (HAP) exposure has been linked to adverse pregnancy outcomes. OBJECTIVES: A randomized controlled trial was undertaken in Ibadan, Nigeria to determine the impact of cooking with ethanol on pregnancy outcomes. METHODS: Three-hundred-twenty-four pregnant women were randomized to either the control (continued cooking using kerosene/firewood stove, n=162) or intervention group (received ethanol stove, n=162)...
December 4, 2017: Environment International
https://www.readbyqxmd.com/read/29190628/cord-blood-biomarkers-of-cardiac-dysfunction-and-damage-in-term-growth-restricted-fetuses-classified-by-severity-criteria
#9
Míriam Perez-Cruz, Fàtima Crispi, María Teresa Fernández, Johanna Alexandra Parra, Anna Valls, María Dolores Gomez Roig, Eduard Gratacós
OBJECTIVE: To assess cardiovascular function and damage in term small-for-gestational-age (SGA) and intrauterine growth-restricted (IUGR) fetuses by echocardiography and biomarkers in cord blood. METHODS: This was a cohort study including 60 normal fetuses and 47 term small fetuses subclassified as small for gestational age (SGA) with estimated fetal weight (EFW) between the 3rd and 9th centiles and normal fetoplacental Doppler (n = 14) or intrauterine growth restriction (IUGR, n = 33) if EFW <3rd centile or EFW <10th centile together with cerebroplacental ratio <5th and/or mean uterine artery pulsatility index >95th centile...
November 30, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29183092/-methamphetamine-consumption-during-pregnancy-and-its-effects-on-neonates
#10
Alina Pflügner, Ulrich Thome, Matthias K Bernhard, Mandy Vogel, Annett Bläser, Petra Nickel, Wieland Kiess
Objective Methamphetamine (MA) has become one of the most commonly used illegal drugs during pregnancy. We sought to determine how MA abuse modifies pregnancy outcomes and the health of the newborn infants. Patients 102 newborns from mothers with antenatal MA consumption were admitted to the University Hospital Leipzig from 2004-2015. Methods The effects of MA abuse on pregnancy outcomes and neonates were researched in a retrospective controlled study. We analysed the date of pregnancy detection, number of antenatal preventive examinations, body measurements of the neonates, duration of hospitalization, rate of preterm infants, congenital malformations and symptoms of neonatal abstinence syndrome...
November 28, 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29157196/perinatal-outcomes-of-hypertensive-disorders-in-pregnancy-at-a-tertiary-hospital-in-ghana
#11
Kwame Adu-Bonsaffoh, Michael Y Ntumy, Samuel A Obed, Joseph D Seffah
BACKGROUND: Hypertensive disorders in pregnancy remain a major global health issue not only because of the associated high adverse maternal outcomes but there is a close accompaniment of significant perinatal morbidity and mortality especially in Sub-Saharan Africa (SSA). However, the perinatal burden of HDP in Ghana has not been explored. We conducted this study to determine the perinatal outcomes of HDP at a tertiary hospital in Ghana. METHODS: A cross-sectional study conducted between January to February 2013 at Korle Bu Teaching Hospital (KBTH) in Accra, Ghana...
November 21, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29149538/psychologic-intimate-partner-violence-and-the-risk-of-intrauterine-growth-restriction-in-rio-de-janeiro
#12
Gustavo Lobato, Michael E Reichenheim, Claudia L Moraes, Fernando M Peixoto-Filho, Lívia S Migowski
OBJECTIVE: To evaluate whether psychologic intimate partner violence (IPV) during pregnancy is a risk factor for intrauterine growth restriction (IUGR). METHODS: The cross-sectional study enrolled 810 randomly selected mothers of infants younger than 5 months attending basic health services in Rio de Janeiro, Brazil, from January to July 2007. Psychologic and physical IPV were evaluated by the Revised Conflict Tactics Scale; IUGR was defined as below the 10th percentile of the Alexander curve...
November 17, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29082792/evaluation-of-late-adolescent-pregnancies-is-late-adolescence-a-risk-factor-for-preterm-labor
#13
Sunullah Soysal, Abdullah Sarioz, Gokce Anik Ilhan, Ali Kocagoz, Aylin Dizi, Ilhan Gursoy, Ipek Celik, Damla Ozmen
STUDY OBJECTIVE: We evaluated effect of late adolescence during pregnancy and its confounding factors on neonatal and maternal results. OBJECTIVE: The aim of the present study is to evaluate the effect of late adolescence on maternal, perinatal outcomes and preterm labor. METHODS: This retrospective study was carried out on 172 late adolescents and 160 adult women who delivered in a tertiary center. The demographic features, obstetrical and neonatal properties of the patients were analyzed...
October 29, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29076132/moderate-to-late-preterm-intrauterine-growth-restriction-a-restrospective-observational-study-of-the-indications-for-delivery-and-outcomes-in-an-australian-perinatal-centre
#14
Bridie Stewart, Amalia Karahalios, Rosalynn Pszczola, Joanne Said
BACKGROUND: The management of preterm intrauterine growth restriction is limited to fetal surveillance and timely delivery. Despite the existence of evidence-based guidelines, uncertainty regarding the optimal timing of delivery is common, and management remains individualised for each patient. AIMS: To provide recent Australian data on the indications for delivery of moderate to late preterm growth restricted infants and the outcomes of these deliveries. MATERIALS AND METHODS: Retrospective study of singleton live births delivered between 32 + 0 and 36 + 6 weeks gestation over a three-year period (2012-2014) at a Melbourne Metropolitan Hospital...
October 27, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29072954/fetal-vascular-malperfusion
#15
REVIEW
Amer Heider
CONTEXT: - Fetal vascular malperfusion, also known as fetal thrombotic vasculopathy, remains an underrecognized pathologic finding and should be noted during placental evaluation. OBJECTIVE: - To review histologic findings, gain familiarity with the updated terminology, and to recognize important clinical associations with this entity. DATA SOURCES: - University of Michigan cases, PubMed search, multiple review articles including recent placental workshop group consensus statement, and selected book chapters...
November 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29063901/eclampsia-in-rural-nigeria-the-unmitigating-catastrophe
#16
Chidi Ochu Uzoma Esike, Ukaegbe Ikechi Chukwuemeka, Okechukwu Bonaventure Anozie, Justus Ndulue Eze, Obioma Christian Aluka, Deirdre Eilleen Twomey
INTRODUCTION: Eclampsia is one of the most dreaded causes of adverse outcomes of pregnancy worldwide. It is one of the greatest causes of maternal and perinatal morbidity and mortality world over. We do not know the prevalence, management outcome, and the devastation caused by this dreaded disease in our center hence the need for this work. MATERIALS AND METHODS: This is a 7-year retrospective review of all cases of eclampsia managed in Mater Misericordiae Hospital Afikpo, a rural secondary cum referral Catholic Mission Hospital in Afikpo, Ebonyi State in Southeastern Nigeria...
October 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/29055052/pregnancy-before-recurrent-pregnancy-loss-more-often-complicated-by-post-term-birth-and-perinatal-death
#17
Marise M Wagner, Jantien Visser, Harjo Verburg, Chantal W P M Hukkelhoven, Jan M M Van Lith, Kitty W M Bloemenkamp
INTRODUCTION: The cause of recurrent pregnancy loss often remains unknown. Possibly, pathophysiological pathways are shared with other pregnancy complications. MATERIAL AND METHODS: All women with secondary recurrent pregnancy loss (SRPL) visiting Leiden University Medical Center (January 2000-2015) were included in this retrospective cohort to assess whether women with SRPL have a more complicated first pregnancy compared with control women. SRPL was defined as three or more consecutive pregnancy losses before 22 weeks of gestation, with a previous birth...
January 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29050752/maternal-substance-use-disorders-and-infant-outcomes-in-the-first-year-of-life-among-massachusetts-singletons-2003-2010
#18
Sunah S Hwang, Hafsatou Diop, Chia-Ling Liu, Qi Yu, Hermik Babakhanlou-Chase, Xiaohui Cui, Milton Kotelchuck
OBJECTIVE: To determine the association of maternal substance use disorders (SUDs) during pregnancy with adverse neonatal outcomes and infant hospital re-admissions, observational stays, and emergency department utilization in the first year of life. STUDY DESIGN: We analyzed 2 linked statewide datasets from 2002 to 2010: the Massachusetts Pregnancy to Early Life Longitudinal data system and the Massachusetts Bureau of Substance Abuse Services Management Information System...
October 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29037170/multidisciplinary-consensus-on-screening-for-diagnosis-and-management-of-fetal-growth-restriction-in-the-netherlands
#19
Viki Verfaille, Ank de Jonge, Lidwine Mokkink, Myrte Westerneng, Henriëtte van der Horst, Petra Jellema, Arie Franx
BACKGROUND: Screening for, diagnosis and management of intrauterine growth restriction (IUGR) is often performed in multidisciplinary collaboration. However, variation in screening methods, diagnosis and management of IUGR may lead to confusion. In the Netherlands two monodisciplinary guidelines on IUGR do not fully align. To facilitate effective collaboration between different professionals in perinatal care, we undertook a Delphi study with uniform recommendations as our primary result, focusing on issues that are not aligned or for which specifications are lacking in the current guidelines...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29016584/morbidities-and-outcome-of-a-neonatal-intensive-care-in-western-nepal
#20
Sudhir Adhikari, Kalipatanam Seshagiri Rao, Ganesh B K, Namraj Bahadur
BACKGROUND: Neonatal mortality rate of developing countries is declining over decades. In the recent years increasing number of preterm and high risk neonates have facilities for tertiary care treatment. The aim of the study was to assess the morbidities and outcome of neonatal intensive care admissions. METHODS: It was a retrospective observational study carried out in neonatal intensive care unit of the Manipal Teaching Hospital, Pokhara, Nepal from January 2014 to December 2015...
September 8, 2017: Journal of Nepal Health Research Council
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