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iugr and perinatal outcome

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https://www.readbyqxmd.com/read/29050752/maternal-substance-use-disorders-and-infant-outcomes-in-the-first-year-of-life-among-massachusetts-singletons-2003-2010
#1
Sunah S Hwang, Hafsatou Diop, Chia-Ling Liu, Qi Yu, Hermik Babakhanlou-Chase, Xiaohui Cui, Milton Kotelchuck
OBJECTIVE: To determine the association of maternal substance use disorders (SUDs) during pregnancy with adverse neonatal outcomes and infant hospital re-admissions, observational stays, and emergency department utilization in the first year of life. STUDY DESIGN: We analyzed 2 linked statewide datasets from 2002 to 2010: the Massachusetts Pregnancy to Early Life Longitudinal data system and the Massachusetts Bureau of Substance Abuse Services Management Information System...
October 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29037170/multidisciplinary-consensus-on-screening-for-diagnosis-and-management-of-fetal-growth-restriction-in-the-netherlands
#2
Viki Verfaille, Ank de Jonge, Lidwine Mokkink, Myrte Westerneng, Henriëtte van der Horst, Petra Jellema, Arie Franx
BACKGROUND: Screening for, diagnosis and management of intrauterine growth restriction (IUGR) is often performed in multidisciplinary collaboration. However, variation in screening methods, diagnosis and management of IUGR may lead to confusion. In the Netherlands two monodisciplinary guidelines on IUGR do not fully align. To facilitate effective collaboration between different professionals in perinatal care, we undertook a Delphi study with uniform recommendations as our primary result, focusing on issues that are not aligned or for which specifications are lacking in the current guidelines...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29016584/morbidities-and-outcome-of-a-neonatal-intensive-care-in-western-nepal
#3
Sudhir Adhikari, Kalipatanam Seshagiri Rao, Ganesh B K, Namraj Bahadur
BACKGROUND: Neonatal mortality rate of developing countries is declining over decades. In the recent years increasing number of preterm and high risk neonates have facilities for tertiary care treatment. The aim of the study was to assess the morbidities and outcome of neonatal intensive care admissions. METHODS: It was a retrospective observational study carried out in neonatal intensive care unit of the Manipal Teaching Hospital, Pokhara, Nepal from January 2014 to December 2015...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28978515/late-gestation-maternal-dietary-methyl-donor-and-cofactor-supplementation-in-sheep-partially-reverses-protection-against-allergic-sensitization-by-iugr
#4
Amy L Wooldridge, Robert J Bischof, Hong Liu, Gary K Heinemann, Damien S Hunter, Lynne C Giles, Rebecca A Simmons, Yu-Chin Lien, Wenyun Lu, Joshua D Rabinowitz, Karen L Kind, Julie A Owens, Vicki L Clifton, Kathryn L Gatford
Perinatal exposures are associated with altered risks of childhood allergy. Human studies and our previous work suggest restricted growth in utero (IUGR) is protective against allergic disease. The mechanisms are not clearly defined but reduced fetal abundance and altered metabolism of methyl donors are hypothesized as possible underlying mechanisms. We therefore examined whether late gestation maternal dietary methyl donor and co-factor supplementation of the placentally-restricted (PR) sheep pregnancy would reverse allergic protection in progeny...
October 4, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28965437/midtrimester-isolated-oligohydramnios-in-monochorionic-diamniotic-multiple-gestations
#5
Andrew H Chon, Lisa M Korst, Ryan D Assaf, Arlyn Llanes, Joseph G Ouzounian, Ramen H Chmait
OBJECTIVE: To describe the natural history and perinatal outcomes of monochorionic diamniotic twins with midtrimester isolated oligohydramnios (iOligo). MATERIALS AND METHODS: We performed a retrospective study of iOligo patients who were initially referred for the management of evolving twin-twin transfusion syndrome (TTTS) or selective intrauterine growth restriction (sIUGR). iOligo was defined as a maximum vertical pocket of amniotic fluid of ≤ 2 cm in the iOligo twin's sac and normal fluid level (> 2 and < 8 cm) in the co-twin's sac...
October 1, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28964834/combined-use-of-serum-gamma-glutamyl-transferase-level-and-ultrasonography-improves-prediction-of-perinatal-outcomes-associated-with-preeclamptic-pregnancy
#6
Juan Wu, Wei Zhou, Quanhua Li, Rui Yuan, Hezhou Li, Shihong Cui
INTRODUCTION: Serum gamma glutamyl transferase (GGT), produced and released mostly from the liver and bile duct, is an enzyme involved in response to oxidative stress, and has been used as a maker for prediction of cardiovascular events. Umbilical artery blood flow resistance index, e.g., the systolic/diastolic ratio (S/D ratio) as determined by ultrasound, has been used to assess the fetal intrauterine conditions. While changes of GGT and S/D ratio in preeclampsia are found to be associated with the risk for adverse perinatal outcome, the potential value of combined use of the two measurements for the prediction of adverse perinatal outcome has not been determined...
September 27, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28927391/grand-multiparity-and-the-possible-risk-of-adverse-maternal-and-neonatal-outcomes-a-dilemma-to-be-deciphered
#7
Ghadeer K Al-Shaikh, Gehan H Ibrahim, Amel A Fayed, Hazem Al-Mandeel
BACKGROUND: The relation between grand multiparity (GMP) and the possible adverse pregnancy outcomes is not well identified. GMP (parity ≥5 births) frequently occurs in the Arab nations; therefore, this study aimed to identify the correlation between GMP and the different adverse maternal and neonatal outcomes in the Saudi population. METHOD: This cohort study was conducted on a total of 3327 women from the labour ward in King Khaled University Hospital, Riyadh, Saudi Arabia...
September 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28832400/predicting-adverse-neonatal-outcome-especially-when-gestational-age-is-uncertain-utility-of-sonographic-measurement-of-fetal-abdominal-wall-thickness
#8
Lei Wu, Michael L Richardson, Theodore Dubinsky
Early and accurate prenatal diagnosis of intrauterine growth restriction is important. Commonly used biometric parameters have limited specificity and require accurate dating. Fetal abdominal wall thickness (AWT) could be a useful supplemental parameter. We performed a retrospective study of 100 third trimester ultrasound exams and compared the sensitivity and specificity of AWT to those of weight percentile (WP) in predicting adverse perinatal outcome.There is a statistically significant difference between the AWT of patients with normal perinatal outcome and that of patients with adverse outcome (P < 0...
September 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/28831553/efficacy-and-safety-of-misoprostol-dinoprostone-and-cook-s-balloon-for-labour-induction-in-women-with-foetal-growth-restriction-at-term
#9
Jorge Duro-Gómez, María Fernanda Garrido-Oyarzún, Ana Belén Rodríguez-Marín, Antonio Jesús de la Torre González, José Eduardo Arjona-Berral, Camil Castelo-Branco
BACKGROUND AND OBJECTIVES: To compare effectiveness and safety of dinoprostone, misoprostol and Cook's balloon as labour-inducing agents in women with intrauterine growth restriction (IUGR) at term. METHODS: Retrospective cohort chart review of women diagnosed with foetal growth restriction at term in Reina Sofia Hospital, Cordoba, Spain from January 2014 to December 2015. Registration of baseline characteristics and method of induction was made. The main outcome was time from induction to delivery...
August 22, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28826263/the-association-between-m%C3%A3-llerian-anomalies-and-perinatal-outcome
#10
Adva Cahen-Peretz, Eyal Sheiner, Michael Friger, Asnat Walfisch
INTRODUCTION: Deviation in the development of the female reproductive organs from the normal anatomy has been shown to have an impact on obstetrical outcomes and neonatal morbidity. MATERIAL AND METHODS: In this retrospective population-based cohort study, short-term neonatal morbidity and mortality were compared in pregnancies of women with and without uterine anomalies. The analysis included deliveries that occurred between the years 1991 and 2013 in a tertiary medical center...
August 21, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28698953/what-can-we-do-to-reduce-the-associated-costs-in-induction-of-labour-of-intrauterine-growth-restriction-foetuses-at-term-a-cost-analysis-study
#11
Jorge Duro-Gómez, María Fernanda Garrido-Oyarzún, Ana Belén Rodríguez-Marín, Antonio Jesús de la Torre González, José Eduardo Arjona-Berral, Camil Castelo-Branco
OBJECTIVE: To evaluate the costs associated with induction of labour in intrauterine growth restriction fetuses comparing different procedures. STUDY DESIGN: 150 pregnancies at term diagnosed with intrauterine growth restriction and indication for induction of labour were included. 24 were ripened with misoprostol 25 μg tablets, 24 with dinoprostone 10 mg vaginal insert, and 77 with Cook(®) cervical ripening balloon. To determine the costs of induction of labour, method of induction, intrapartum medication, epidural analgesia, type of delivery, and maternal and neonatal admissions were considered...
July 11, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28691603/dichorionic-twins-discordant-for-massive-perivillous-fibrinoid-deposition-report-of-a-case-and-review-of-the-literature
#12
Ona Faye-Petersen, Adrienne Sauder, Ydamis Estrella, Debra S Heller
Massive perivillous fibrinoid deposition (MFD) and maternal floor infarction (MFI) are lesions of unknown etiology associated with poor perinatal outcomes, including fetal intrauterine growth restriction and neurodevelopmental injury, high risks of pregnancy loss, and recurrence in subsequent gestations. MFI comprises massive intervillous fibrinoid deposition concentrated at the maternal floor. MFD is a similar lesion but is diffuse within the parenchyma. MFD/MFI lesions represent a spectrum of severity of cloak-like perivillous fibrinoid deposition, and there is mounting evidence that, often, they represent sequelae of immune-mediated phenomena and/or an imbalance in factors that normally maintain the fluidity of blood in the maternal space...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28651459/-examination-of-placental-three-dimensional-power-doppler-indices-and-perinatal-outcome-in-pregnancies-complicated-by-intrauterine-growth-restriction
#13
András Molnár, Andrea Surányi, Mária Jakó, Tibor Nyári, Gábor Németh
INTRODUCTION: Development of intrauterine growth restriction (IUGR) can be traced back to maternal or fetal factors, but in many cases we find placental factors (reduced placental circulation) in the background. AIM: Our aim was to examine whether the reduced placental bloodperfusion and vascularity show any correlation with cesarean section frequency and the clinical outcome in IUGR pregnancies. The aim of the present study was also to use a properly calibrated and reproducible method for evaluating placental blood flow, that can later be incorporated into the routine examination...
July 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28606451/peak-serum-estradiol-level-during-controlled-ovarian-stimulation-is-not-associated-with-lower-levels-of-pregnancy-associated-plasma-protein-a-or-small-for-gestational-age-infants-a-cohort-study
#14
Caitlin Dunne, Kristy Cho, Angel Shan, Jennifer Hutcheon, Ursula Smith Durland, Ken Seethram, Jon C Havelock
OBJECTIVE: During controlled ovarian stimulation in IVF, supraphysiologic levels of estradiol (E2) have been associated with poor placentation and adverse pregnancy outcomes. This study aimed to investigate whether high peak E2 on the day of human chorionic gonadotropin trigger is associated with low pregnancy-associated plasma protein-A (PAPP-A) and adverse perinatal outcomes. METHODS: We performed a retrospective cohort study at a private, university-affiliated fertility centre in Vancouver, BC...
June 9, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28600043/placenta-associated-pregnancy-complications-in-pregnancies-complicated-with-placenta-previa
#15
Yael Baumfeld, Reli Herskovitz, Zehavi Bar Niv, Salvatore Andrea Mastrolia, Adi Y Weintraub
OBJECTIVES: The purpose of our study was to examine the hypothesis that pregnancies complicated with placenta previa have an increased risk of placental insufficiency associated pregnancy complications (IUGR, preeclampsia, placental abruption and perinatal mortality). MATERIALS AND METHODS: Our study included all deliveries that occurred at Soroka University Medical Center (Beer Sheva, Israel) between January 1998 and December 2013. Of them 1,249 were complicated by placenta previa and represented our study group...
June 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28549983/the-effect-of-omega-3-supplementation-on-pregnancy-outcomes-by-smoking-status
#16
RANDOMIZED CONTROLLED TRIAL
Spencer G Kuper, Adi R Abramovici, Victoria C Jauk, Lorie M Harper, Joseph R Biggio, Alan T Tita
BACKGROUND: Smoking during pregnancy is associated with adverse maternal and neonatal outcomes such as preterm delivery, intrauterine growth restriction, stillbirth, and low birth weight. Because smoking causes oxidative stress, some have suggested using antioxidants to counteract the effects of oxidative stress. Smokers have lower serum levels of omega-3 fatty acids, an important antioxidant, and thus, investigating whether omega-3 supplementation in smokers reduces adverse maternal and neonatal outcomes represents an important area of research...
October 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28547098/obstetrical-and-perinatal-morbidity-and-mortality-among-in-vitro-fertilization-pregnancies-a-population-based-study
#17
Hussein Sabban, Andrew Zakhari, Valerie Patenaude, Togas Tulandi, Haim A Abenhaim
PURPOSE: To compare patient characteristics and obstetrical/neonatal outcomes of in-vitro fertilization (IVF) and spontaneously conceived pregnancies. METHODS: Using the Nationwide Inpatient Sample, we conducted a retrospective cohort study from 2008 to 2011 comparing IVF conceptions to spontaneous ones. Patient characteristics were descriptively compared, and after adjusting for baseline characteristics with logistic regression, obstetrical/neonatal outcomes were also compared...
July 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28544517/fetoscopic-laser-photocoagulation-for-amniotic-fluid-discordance-bordering-on-twin-twin-transfusion-syndrome-feasibility-perinatal-and-long-term-outcomes
#18
Katsusuke Ozawa, Rika Sugibayashi, Seiji Wada, Masahiro Sumie, Keisuke Ishii, Masahiko Nakata, Takeshi Murakoshi, Yushi Ito, Haruhiko Sago
AIM: This study investigated the feasibility and safety of fetoscopic laser photocoagulation (FLP) for amniotic fluid discordance (AFD) bordering on twin-twin transfusion syndrome (TTTS) with an absent or reverse end-diastolic velocity (AREDV) in the umbilical artery (UA), and evaluated the perinatal and long-term outcomes. METHODS: A prospective intervention study was performed between 20 + 0 and 25 + 6 weeks of gestation (UMIN000004165). AFD bordering on TTTS was defined as maximum vertical pocket (MVP) of amniotic fluid in one twin's sac ≤3 cm and amniotic fluid MVP in the other twin's sac ≥7 cm excluding TTTS...
May 19, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28528221/bronchopulmonary-dysplasia-and-perinatal-characteristics-predict-1-year-respiratory-outcomes-in-newborns-born-at-extremely-low-gestational-age-a-prospective-cohort-study
#19
MULTICENTER STUDY
Roberta L Keller, Rui Feng, Sara B DeMauro, Thomas Ferkol, William Hardie, Elizabeth E Rogers, Timothy P Stevens, Judith A Voynow, Scarlett L Bellamy, Pamela A Shaw, Paul E Moore
OBJECTIVE: To assess the utility of clinical predictors of persistent respiratory morbidity in extremely low gestational age newborns (ELGANs). STUDY DESIGN: We enrolled ELGANs (<29 weeks' gestation) at ≤7 postnatal days and collected antenatal and neonatal clinical data through 36 weeks' postmenstrual age. We surveyed caregivers at 3, 6, 9, and 12 months' corrected age to identify postdischarge respiratory morbidity, defined as hospitalization, home support (oxygen, tracheostomy, ventilation), medications, or symptoms (cough/wheeze)...
August 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28514879/growth-restriction-identifying-fetuses-at-risk
#20
Heidi K Leftwich, Bethany Stetson, Bethany Sabol, Katherine Leung, Judith U Hibbard, Isabelle Wilkins
PURPOSE: Examine risks of intrauterine growth restriction (IUGR) and composite perinatal outcomes with estimated fetal weights (EFW) 10-20(th)%, and compare outcomes using umbilical artery Doppler (UAD). MATERIALS AND METHODS: Retrospective, cohort evaluating ultrasound (US) EFW 10th-20(th)%, between 2002-2012. Cases were identified with EFW % 10-20. Controls, EFW >20(th)% were obtained for each case, matched by gestational age and US date. Unadjusted and adjusted logistic regression was used for outcomes...
May 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
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