keyword
MENU ▼
Read by QxMD icon Read
search

Meta analysis

keyword
https://www.readbyqxmd.com/read/28092847/repetitive-transcranial-magnetic-stimulation-for-the-treatment-of-post-stroke-depression-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#1
REVIEW
XinYi Shen, MingYi Liu, Yu Cheng, Cui Jia, XinYue Pan, QingYun Gou, XinLian Liu, Hui Cao, LuShun Zhang
BACKGROUND: Every year, more than fifteen million people worldwide experience a stroke, nearly 30% of stroke survivors are likely to experience post-stroke depression (PSD). Repetitive transcranial magnetic stimulation (rTMS) is one of the emerging techniques which assist in targeting rehabilitation after stroke. Although deterioration of PSD greatly affects the recovery and quality of life of stroke sufferers, the effect of rTMS therapy has not been systematically studied. OBJECTIVE: A systematic review and meta-analysis was conducted to determine the effect of rTMS on PSD...
January 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28092788/patient-level-meta-analysis-of-efficacy-and-hypoglycaemia-in-people-with-type-2-diabetes-initiating-insulin-glargine-100u-ml-or-neutral-protamine-hagedorn-insulin-analysed-according-to-concomitant-oral-antidiabetes-therapy
#2
David R Owens, Louise Traylor, Peter Mullins, Wolfgang Landgraf
AIMS: Evaluate efficacy and hypoglycaemia according to concomitant oral antidiabetes drug (OAD) in people with type 2 diabetes initiating insulin glargine 100U/mL (Gla-100) or neutral protamine Hagedorn (NPH) insulin once daily. METHODS: Four studies (target fasting plasma glucose [FPG] ⩽100mg/dL [⩽5.6mmol/L]; duration ⩾24weeks) were included. Standardised data from 2091 subjects (Gla-100, n=1024; NPH insulin, n=1067) were analysed. Endpoints included glycated haemoglobin (HbA1c) and FPG change, glycaemic target achievement, hypoglycaemia, weight change, and insulin dose...
November 9, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28092683/case-control-association-mapping-by-proxy-using-family-history-of-disease
#3
Jimmy Z Liu, Yaniv Erlich, Joseph K Pickrell
Collecting cases for case-control genetic association studies can be time-consuming and expensive. In some situations (such as studies of late-onset or rapidly lethal diseases), it may be more practical to identify family members of cases. In randomly ascertained cohorts, replacing cases with their first-degree relatives enables studies of diseases that are absent (or nearly absent) in the cohort. We refer to this approach as genome-wide association study by proxy (GWAX) and apply it to 12 common diseases in 116,196 individuals from the UK Biobank...
January 16, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28092576/multiple-instance-learning-for-medical-image-and-video-analysis
#4
Gwenole Quellec, Guy Cazuguel, Beatrice Cochener, Mathieu Lamard
Multiple-Instance Learning (MIL) is a recent machine learning paradigm that is particularly well suited to Medical Image and Video Analysis (MIVA) tasks. Based solely on class labels assigned globally to images or videos, MIL algorithms learn to detect relevant patterns locally in images or videos. These patterns are then used for classification at a global level. Because supervision relies on global labels, manual segmentations are not needed to train MIL algorithms, unlike traditional Single-Instance Learning (SIL) algorithms...
January 10, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28092497/polymyxin-b-hemoperfusion-for-sepsis-and-septic-shock-a-systematic-review-and-meta-analysis
#5
Takero Terayama, Kazuma Yamakawa, Yutaka Umemura, Morio Aihara, Satoshi Fujimi
BACKGROUND: To evaluate the efficacy and safety of direct hemoperfusion with polymyxin B-immobilized fiber (PMX-DHP) therapy in patients with sepsis. DESIGN: A systematic review and meta-analysis of four major databases: Cochrane Central Register of Controlled Trials, MEDLINE, Scopus, and Science Citation Index Expanded. STUDY SELECTION: Randomized controlled trials comparing PMX-DHP with conventional therapy on the outcome of mortality in patients with severe sepsis/septic shock...
January 16, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28092289/the-impact-of-obesity-on-heart-failure
#6
Alexander B Zhai, Haissam Haddad
PURPOSE OF REVIEW: Obesity, a growing global health problem, contributes to the development of heart failure. However, increased BMI seems protective for those with established disease, a phenomenon known as the 'obesity paradox'. In this review, we outline the mechanism through which obesity can contribute to the development of heart failure, explore the concept of obesity paradox, and highlight the challenges that obesity presents for advanced heart failure therapy. RECENT FINDINGS: Although the mechanism underlying the obesity paradox is complex, meta-analysis shows that intentional weight loss through bariatric surgery can indeed improve cardiac structure and function...
January 13, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28092087/retraction-note-to-the-impact-of-survivin-on-prognosis-and-clinicopathology-of-glioma-patients-a-systematic-meta-analysis
#7
Shunzeng Lv, Congxin Dai, Yuting Liu, Ranran Shi, Zhenyu Tang, Mingzhi Han, Ruixiang Bian, Bowen Sun, Renzhi Wang
No abstract text is available yet for this article.
January 16, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28091976/effectiveness-of-various-innovative-learning-methods-in-health-science-classrooms-a-meta-analysis
#8
Sema A Kalaian, Rafa M Kasim
This study reports the results of a meta-analysis of the available literature on the effectiveness of various forms of innovative small-group learning methods on student achievement in undergraduate college health science classrooms. The results of the analysis revealed that most of the primary studies supported the effectiveness of the small-group learning methods in improving students' academic achievement with an overall weighted average effect-size of 0.59 in standard deviation units favoring small-group learning methods...
January 13, 2017: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/28091808/occupational-and-environmental-scleroderma-systematic-review-and-meta-analysis
#9
Manuel Rubio-Rivas, Rafael Moreno, Xavier Corbella
The etiology of systemic sclerosis (SSc) remains unknown; however, several occupational and environmental factors have been implicated. Our objective was to perform a meta-analysis of all studies published on SSc associated with occupational and environmental exposure. The review was undertaken by means of MEDLINE and SCOPUS from 1960 to 2014 and using the terms: "systemic," "scleroderma," or "systemic sclerosis/chemically induced" [MesH]. The Newcastle-Ottawa Scale was used for the qualifying assessment. The inverse variance-weighted method was performed...
January 14, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28091622/clinical-variations-in-parkinson-s-disease-patients-with-or-without-rem-sleep-behaviour-disorder-a-meta-analysis
#10
Ruo-Lin Zhu, Cheng-Juan Xie, Pan-Pan Hu, Kai Wang
This study aimed to evaluate the clinical variations in patients with Parkinson's disease (PD) with (PDRBD) or without REM sleep behaviour disorder (RBD) (Non-RBD), and PDRBD patients were classified into Confirmed-RBD (definite diagnosis with polysomnography, PSG) and Probable-RBD (without PSG re-confirmation). The clinical difference between the groups of patients was measured as an odds ratio (OR) or standardized mean difference (SMD, Cohen d). A total of 31 articles with data from 5,785 participants were obtained for our analysis...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28091563/androgen-receptor-gene-polymorphisms-and-risk-of-prostate-cancer-a-meta-analysis
#11
Hong Weng, Sheng Li, Jing-Yu Huang, Zi-Qi He, Xiang-Yu Meng, Yue Cao, Cheng Fang, Xian-Tao Zeng
Although the association between CAG and GGN repeats in the androgen receptor gene and prostate cancer risk has been widely studied, it remains controversial from previous meta-analyses and narrative reviews. Therefore, we performed this meta-analysis to provide more precise estimates with sufficient power. A total of 51 publications with 61 studies for CAG repeats and 14 publications with 16 studies for GGN repeats were identified in the meta-analysis. The results showed that short CAG repeats (<22 repeats) carriers presented an elevated risk of prostate cancer than long CAG repeats (≥22) carriers (OR = 1...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28091359/phyto-oestrogens-and-colorectal-cancer-risk-a-systematic-review-and-dose-response-meta-analysis-of-observational-studies
#12
Ruijingfang Jiang, Akke Botma, Anja Rudolph, Anika Hüsing, Jenny Chang-Claude
Epidemiological studies suggest that soya consumption as a source of phyto-oestrogens and isoflavones may be associated with a reduced risk of colorectal cancer. However, findings have not yet been synthesised for all groups of phyto-oestrogens. A meta-analysis was conducted to quantify the association between phyto-oestrogens and colorectal cancer risk. Relevant observational studies published up to June 2016 were identified by searching MEDLINE, EMBASE and Cochrane Library databases. Study-specific relative risks (RR) were pooled in both categorical and dose-response meta-analyses...
January 16, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28091355/a-systematic-review-evaluating-the-impact-of-paid-home-carer-training-supervision-and-other-interventions-on-the-health-and-well-being-of-older-home-care-clients
#13
Claudia Cooper, Blerta Cenko, Briony Dow, Penny Rapaport
BACKGROUND: Interventions to support and skill paid home carers and managers could potentially improve health and well-being of older home care clients. This is the first systematic review of interventions to improve how home carers and home care agencies deliver care to older people, with regard to clients' health and well-being and paid carers' well-being, job satisfaction, and retention. METHODS: We reviewed 10/731 papers found in the electronic search (to January 2016) fitting predetermined criteria, assessed quality using a checklist, and synthesized data using quantitative and qualitative techniques...
January 16, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28091344/a-comprehensive-systematic-review-and-meta-analysis-of-pharmacological-and-dietary-supplement-interventions-in-paediatric-autism-moderators-of-treatment-response-and-recommendations-for-future-research
#14
A Masi, A Lampit, M M DeMayo, N Glozier, I B Hickie, A J Guastella
BACKGROUND: Autism spectrum disorders (ASDs) are pervasive and multifactorial neurodevelopmental conditions, characterized by impairments in social communication and interaction, and restricted, repetitive patterns of behaviour, interests or activities. Treatment options to ameliorate symptoms of ASDs are limited. Heterogeneity complicates the quest for personalized medicine in this population. Our aim was to investigate if there are baseline characteristics of patients that moderate response or trial design features that impede the identification of efficacious interventions for ASDs...
January 16, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28090819/toxoplasmic-encephalitis-relapse-rates-with-pyrimethamine-based-therapy-systematic-review-and-meta-analysis
#15
Mark P Connolly, Elizabeth Goodwin, Carina Schey, Jacqueline Zummo
Toxoplasmic encephalitis (TE) is caused by Toxoplasma gondii infection and can be a life-threatening disease in immunocompromised patients. This study evaluated the rate of relapse associated with pyrimethamine-based maintenance therapy (i.e. secondary prophylaxis) in patients with human immunodeficiency virus (HIV) or AIDs treated prior to and after the common use (i.e. 1996) of highly active antiretroviral therapy (HAART) (pre-HAART and post-HAART, respectively). PubMed, Google Scholar, and Cochrane databases were searched to 6 June 2016 using search terms: pyrimethamine, Daraprim, Fansidar, Metakelfin, Fansimef, 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine, encephalitis, cerebral, toxoplasmosis, toxoplasmic, and gondii...
January 16, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28090814/personalized-dynamic-prediction-of-death-according-to-tumour-progression-and-high-dimensional-genetic-factors-meta-analysis-with-a-joint-model
#16
Takeshi Emura, Masahiro Nakatochi, Shigeyuki Matsui, Hirofumi Michimae, Virginie Rondeau
Developing a personalized risk prediction model of death is fundamental for improving patient care and touches on the realm of personalized medicine. The increasing availability of genomic information and large-scale meta-analytic data sets for clinicians has motivated the extension of traditional survival prediction based on the Cox proportional hazards model. The aim of our paper is to develop a personalized risk prediction formula for death according to genetic factors and dynamic tumour progression status based on meta-analytic data...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/28090807/neurocognitive-function-in-pediatric-obsessive-compulsive-disorder
#17
Daniel A Geller, Amitai Abramovitch, Andrew Mittelman, Abigail Stark, Kesley Ramsey, Allison Cooperman, Lee Baer, S Evelyn Stewart
OBJECTIVES: The small body of neuropsychological research in pediatric OCD yields inconsistent results. A recent meta-analysis found small effect sizes, concluding that pediatric OCD may not be associated with cognitive impairments, stressing the need for more research. We investigated neuropsychological performance in a large sample of OCD youth, while assessing potential moderators. METHODS: Participants with OCD (n = 102), and matched controls (n = 161) were thoroughly screened and blindly evaluated for comorbidities, and completed a neuropsychological battery assessing processing-speed, visuospatial abilities (VSA), working memory (WM), nonverbal memory (NVM), and executive functions (EF)...
January 16, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28090760/expression-patterns-of-cardiac-aging-in-drosophila
#18
Leah Cannon, Alexander C Zambon, Anthony Cammarato, Zhi Zhang, Georg Vogler, Matthew Munoz, Erika Taylor, Jérôme Cartry, Sanford I Bernstein, Simon Melov, Rolf Bodmer
Aging causes cardiac dysfunction, often leading to heart failure and death. The molecular basis of age-associated changes in cardiac structure and function is largely unknown. The fruit fly, Drosophila melanogaster, is well-suited to investigate the genetics of cardiac aging. Flies age rapidly over the course of weeks, benefit from many tools to easily manipulate their genome, and their heart has significant genetic and phenotypic similarities to the human heart. Here, we performed a cardiac-specific gene expression study on aging Drosophila and carried out a comparative meta-analysis with published rodent data...
February 2017: Aging Cell
https://www.readbyqxmd.com/read/28090724/efficacy-of-topical-insulin-in-wound-healing-a-preliminary-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
Kannan Sridharan, Gowri Sivaramakrishnan
Topical insulin has been shown to promote wound healing in various studies. Considering the absence of a systematic review and quantitative synthesis on the same, the present study was carried out. Using an appropriate search strategy, electronic databases were searched for randomized controlled trials that have compared topical application of insulin in wounds with normal saline. Standardize mean differences were calculated for the following outcome measures: healing rate of ulcers/wound, percent granulation tissue growth, micro vessel density, time to heal, wound area and ulcer severity score...
January 16, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28090704/effectiveness-of-telephone-based-interventions-on-health-related-quality-of-life-and-prognostic-outcomes-in-breast-cancer-patients-and-survivors-a-meta-analysis
#20
REVIEW
Q Zhang, L Zhang, R Yin, T Fu, H Chen, B Shen
The aim of this meta-analysis was to evaluate the effect of telephone-based interventions on prognostic outcomes and health-related quality of life (HRQoL) in breast cancer patients and survivors. A systematic search of the Cochrane Library, Web of science, Medline, EMBASE, CNKI and CBM database was carried out. Randomised, controlled trials (RCTs) examining the effects of telephone-based intervention versus a control group receiving no telephone intervention, on prognostic outcomes and HRQoL with breast cancer were included...
January 16, 2017: European Journal of Cancer Care
keyword
keyword
4250
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"