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https://www.readbyqxmd.com/read/29029324/cadmium-exposure-impairs-cognition-and-olfactory-memory-in-male-c57bl-6-mice
#1
Hao Wang, Liang Zhang, Glen M Abel, Daniel R Storm, Zhengui Xia
Cadmium (Cd) is a heavy metal of high interest to the Superfund Initiative. Recent epidemiology studies have suggested a possible association between Cd exposure and cognitive as well as olfactory impairments in humans. However, studies in animal models are needed to establish a direct causal relationship between Cd exposure and impairments in cognition and olfaction. This study aims to investigate the toxic effect of Cd on cognition and olfactory function in mice. One group of 8-week old C57BL/6 male mice was exposed to 3 mg/L Cd (in the form of CdCl2) through drinking water for 20 weeks for behavior tests and final blood Cd concentration analysis...
September 25, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29029208/dust-storms-heart-attacks-and-protecting-those-at-risk
#2
Mary B Rice, Murray A Mittleman
No abstract text is available yet for this article.
September 23, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29029188/an-analysis-of-the-epidemic-of-kpc-producing-klebsiella-pneumoniae-convergence-of-two-evolutionary-mechanisms-creates-the-perfect-storm
#3
Laura J Rojas, George M Weinstock, Elsa De La Cadena, Lorena Diaz, Rafael Rios, Blake M Hanson, Joseph S Brown, Purva Vats, Daniel S Phillips, Hoan Nguyen, Kristine M Hujer, Adriana Correa, Mark D Adams, Federico Perez, Erica Sodergren, Apurva Narechania, Paul J Planet, Maria V Villegas, Robert A Bonomo, Cesar A Arias
Background: Carbapenem resistance is a critical health care challenge worldwide. Particularly concerning is the widespread dissemination of Klebsiella pneumoniae carbapenemase (KPC). K. pneumoniae harboring blaKPC (KPC-Kpn) is endemic in many areas including United States, where the epidemic was primarily mediated by the clonal dissemination of Kpn ST258. We postulated that the spread of blaKPC in other regions occurs by different and more complex mechanisms. To test this, we investigated the evolution and dynamics of spread of KPC-Kpn in Colombia, where KPC became rapidly endemic after emerging in 2005...
September 27, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29028638/malignant-hyperthermia-versus-thyroid-storm-in-a-patient-with-symptomatic-graves-disease-a-case-report
#4
Sara M Strowd, Michael B Majewski, Jennifer Asteris
Malignant hyperthermia and thyroid storm are intraoperative emergencies with overlapping symptoms but different treatment protocols. We faced this diagnostic dilemma in a 25-year-old patient with symptomatic hyperthyroidism, elevated free T3 and free T4, and low thyroid-stimulating hormone from Graves disease despite treatment with propranolol 80 mg daily and methimazole 40 mg every 8 hours. During thyroidectomy, he developed hyperthermia and hypercarbia without tachycardia. When the rate of rise of PaCO2 and temperature accelerated, we treated the patient for malignant hyperthermia, a diagnosis subsequently confirmed by genetic testing...
October 12, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29027996/aquatic-urban-ecology-at-the-scale-of-a-capital-community-structure-and-interactions-in-street-gutters
#5
Vincent Hervé, Boris Leroy, Albert Da Silva Pires, Pascal Jean Lopez
In most cities, streets are designed for collecting and transporting dirt, litter, debris, storm water and other wastes as a municipal sanitation system. Microbial mats can develop on street surfaces and form microbial communities that have never been described. Here, we performed the first molecular inventory of the street gutter-associated eukaryotes across the entire French capital of Paris and the non-potable waters sources. We found that the 5782 OTUs (operational taxonomic units) present in the street gutters which are dominated by diatoms (photoautotrophs), fungi (heterotrophs), Alveolata and Rhizaria, includes parasites, consumers of phototrophs and epibionts that may regulate the dynamics of gutter mat microbial communities...
October 13, 2017: ISME Journal
https://www.readbyqxmd.com/read/29026879/tsunamis-in-the-geological-record-making-waves-with-a-cautionary-tale-from-the-mediterranean
#6
Nick Marriner, David Kaniewski, Christophe Morhange, Clément Flaux, Matthieu Giaime, Matteo Vacchi, James Goff
From 2000 to 2015, tsunamis and storms killed more than 430,000 people worldwide and affected a further >530 million, with total damages exceeding US$970 billion. These alarming trends, underscored by the tragic events of the 2004 Indian Ocean catastrophe, have fueled increased worldwide demands for assessments of past, present, and future coastal risks. Nonetheless, despite its importance for hazard mitigation, discriminating between storm and tsunami deposits in the geological record is one of the most challenging and hotly contended topics in coastal geoscience...
October 2017: Science Advances
https://www.readbyqxmd.com/read/29025556/patients-with-brugada-syndrome-and-implanted-cardioverter-defibrillators-long-term-follow-up
#7
Jaime Hernandez-Ojeda, Elena Arbelo, Roger Borras, Paola Berne, Jose M Tolosana, Andrea Gomez-Juanatey, Antonio Berruezo, Oscar Campuzano, Georgia Sarquella-Brugada, Lluis Mont, Ramon Brugada, Josep Brugada
BACKGROUND: Implantable cardioverter-defibrillator (ICD) indications for primary prevention in Brugada syndrome (BrS) are still debated. OBJECTIVES: The authors investigated the long-term outcome after ICD implantation in a large cohort of BrS patients. METHODS: Of a total of 370 patients with BrS in follow-up (age 43 ± 14 years; 74% male), 104 patients (28.1%) were treated with ICDs. The authors analyzed the long-term incidence of shocks and complications...
October 17, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29024705/management-of-a-circumferential-duodenal-polyp
#8
Andrew C Storm, Mark D Topazian
No abstract text is available yet for this article.
October 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29022167/stochastic-evaluation-of-annual-micropollutant-loads-and-their-uncertainties-in-separate-storm-sewers
#9
Ali Hannouche, Ghassan Chebbo, Claude Joannis, Johnny Gasperi, Marie-Christine Gromaire, Régis Moilleron, Sylvie Barraud, Véronique Ruban
This article describes a stochastic method to calculate the annual pollutant loads and its application over several years at the outlet of three catchments drained by separate storm sewers. A stochastic methodology using Monte Carlo simulations is proposed for assessing annual pollutant load, as well as the associated uncertainties, from a few event sampling campaigns and/or continuous turbidity measurements (representative of the total suspended solids concentration (TSS)). Indeed, in the latter case, the proposed method takes into account the correlation between pollutants and TSS...
October 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29021859/the-electrical-circuit-of-a-hemodynamically-unstable-and-recurrent-ventricular-tachycardia-diagnosed-in-35%C3%A2-s-with-the-rhythmia-mapping-system
#10
Masateru Takigawa, Antonio Frontera, Nathaniel Thompson, Stefano Capellino, Pierre Jais, Frederic Sacher
Herein, we report a 47-year-old woman with ischemic cardiomyopathy who underwent ablation therapy due to an electrical storm without any triggers. The voltage mapping in sinus rhythm with the Rhythmia system and Orion catheter displayed several LAVAs in and around the anteroapical scar area. Although the patient did not tolerate the induced clinical ventricular tachycardia, which was reproductively induced, 35-second-mapping in the scar zone with the Orion catheter demonstrated the VT circuit with the critical isthmus...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29021858/landiolol-suppression-of-electrical-storm-of-torsades-de-pointes-in-patients-with-congenital-long-qt-syndrome-type-2-and-myocardial-ischemia
#11
Ryota Kitajima, Takeshi Aiba, Tsukasa Kamakura, Kohei Ishibashi, Mitsuru Wada, Yuko Inoue, Koji Miyamoto, Hideo Okamura, Takashi Noda, Satoshi Nagase, Yu Kataoka, Yasuhide Asaumi, Teruo Noguchi, Satoshi Yasuda, Kengo Kusano
A 76-year-old man who had been diagnosed with long-QT syndrome type 2 had frequent syncopal attacks. The electrocardiogram was monitored, and frequent torsades de pointes (TdP) was detected despite administration of conventional medications: oral propranolol, verapamil, intravenous magnesium sulfate, verapamil, and lidocaine. In contrast, 2 μg/kg/min landiolol could completely suppress TdP. Subsequently, an implantable cardioverter defibrillator was placed, and he was diagnosed with silent myocardial ischemia using myocardial perfusion scintigraphy and coronary angiography...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29021632/arctic-cryosphere-and-milankovitch-forcing-of-great-basin-paleoclimate
#12
Matthew Lachniet, Yemane Asmerom, Victor Polyak, Rhawn Denniston
Although Great Basin paleoclimate history has been examined for more than a century, the orbital-scale paleoclimate forcings remain poorly understood. Here we show - by a detailed phasing analysis of a well-dated stalagmite δ(18)O time series - that Great Basin paleoclimate is linearly related to, but lagged, the 23,000 yr precession cycle in northern hemisphere summer insolation by an average of 3240 years (-900 to 6600 yr range) over the last two glacial cycles. We interpret these lags as indicating that Great Basin climate is sensitive to and indirectly forced by changes in the cryosphere, as evidenced by fast and strong linkages to global ice volume and Arctic paleoclimate indicators...
October 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29019953/assessment-of-ionospheric-gradient-impacts-on-ground-based-augmentation-system-gbas-data-in-guangdong-province-china
#13
Zhipeng Wang, Shujing Wang, Yanbo Zhu, Pumin Xin
Ionospheric delay is one of the largest and most variable sources of error for Ground-Based Augmentation System (GBAS) users because inospheric activity is unpredictable. Under normal conditions, GBAS eliminates ionospheric delays, but during extreme ionospheric storms, GBAS users and GBAS ground facilities may experience different ionospheric delays, leading to considerable differential errors and threatening the safety of users. Therefore, ionospheric monitoring and assessment are important parts of GBAS integrity monitoring...
October 11, 2017: Sensors
https://www.readbyqxmd.com/read/29018522/ventricular-arrhythmia-after-acute-myocardial-infarction-the-perfect-storm
#14
Justine Bhar-Amato, William Davies, Sharad Agarwal
Ventricular tachyarrhythmias (VAs) commonly occur early in ischaemia, and remain a common cause of sudden death in acute MI. The thrombolysis and primary percutaneous coronary intervention era has resulted in the modification of the natural history of an infarct and subsequent VA. Presence of VA could independently influence mortality in patients recovering from MI. Appropriate risk assessment and subsequent treatment is warranted in these patients. The prevention and treatment of haemodynamically significant VA in the post-infarct period and of sudden cardiac death remote from the event remain areas of ongoing study...
August 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/28994718/efficient-usage-of-dense-gnss-networks-in-central-europe-for-the-visualization-and-investigation-of-ionospheric-tec-variations
#15
Grzegorz Nykiel, Yevgen M Zanimonskiy, Yuri M Yampolski, Mariusz Figurski
The technique of the orthogonal projection of ionosphere electronic content variations for mapping total electron content (TEC) allows us to visualize ionospheric irregularities. For the reconstruction of global ionospheric characteristics, numerous global navigation satellite system (GNSS) receivers located in different regions of the Earth are used as sensors. We used dense GNSS networks in central Europe to detect and investigate a special type of plasma inhomogeneities, called travelling ionospheric disturbances (TID)...
October 10, 2017: Sensors
https://www.readbyqxmd.com/read/28993926/effects-of-dust-on-forest-tree-health-in-zagros-oak-forests
#16
A Moradi, K Taheri Abkenar, M Afshar Mohammadian, N Shabanian
Dust is one of the most devastating factors for the environment threatening all animal and plant species. In many regions, the ecological and economic impact of microdust on scarce species is critical. In the western region of Iran, the Zagros forests have been exposed to dust storms for many years. In this study, the effect of dust on oak trees, the most important trees of Zagros forests, is investigated. For this purpose, 3-year-old seedlings of three species of oak trees under natural conditions were exposed to dust during spring and summer months...
October 10, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28992561/bridging-the-gap-between-the-randomised-clinical-trial-world-and-the-real-world-by-combination-of-population-based-registry-and-electronic-health-record-data-a-case-study-in-haemato-oncology
#17
REVIEW
R E Kibbelaar, B E Oortgiesen, A M van der Wal-Oost, K Boslooper, J W Coebergh, N J G M Veeger, P Joosten, H Storm, E N van Roon, M Hoogendoorn
Randomised clinical trials (RCTs) are considered the basis of evidence-based medicine. It is recognised more and more that application of RCT results in daily practice of clinical decision-making is limited because the RCT world does not correspond with the clinical real world. Recent strategies aiming at substitution of RCT databases by improved population-based registries (PBRs) or by improved electronic health record (EHR) systems to provide significant data for clinical science are discussed. A novel approach exemplified by the HemoBase haemato-oncology project is presented...
October 6, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28991989/impact-of-roadway-stormwater-runoff-on-microbial-contamination-in-the-receiving-stream
#18
Kristen N Wyckoff, Si Chen, Andrew J Steinman, Qiang He
Stormwater runoff from roadways has increasingly become a regulatory concern for water pollution control. Recent work has suggested roadway stormwater runoff as a potential source of microbial pollutants. The objective of this study was to determine the impact of roadway runoff on the microbiological quality of receiving streams. Microbiological quality of roadway stormwater runoff and the receiving stream was monitored during storm events with both cultivation-dependent fecal bacteria enumeration and cultivation-independent high-throughput sequencing techniques...
September 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28991987/predictors-of-phosphorus-leaching-from-bioretention-soil-media
#19
Julia G Jay, Sally L Brown, Kate Kurtz, Fritz Grothkopp
The phosphorus saturation index (PSI) and P saturation ratio (PSR) were tested across a wide range of bioretention soil mixtures (BSMs) for their relationship to total and dissolved P in column leachate. The BSMs tested were made using different feedstocks including sand alone, food and yard waste compost, biosolids and yard compost, and high Fe biosolids. The PSI of the mixtures ranged from 0.23 ± 0.03 (biosolids and yard waste compost 15%, oyster shells 5%) to 1.26 ± 0.02 (biosolids and yard waste compost 80%)...
September 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28991291/s%C3%A3-ndrome-antifosfol%C3%A3-pidos-catastr%C3%A3-fico-reporte-de-caso-y-revisi%C3%A3-n-bibliogr%C3%A3-fica
#20
Luis Del Carpio Orantes, Chantall Citlally Anaya Martínez, Elías Bonilla Casas
other: Se reporta un caso de una condición clínica sumamente rara, la cual cursa con falla multiorgánica aguda posterior a una tormenta trombótica relacionada con anticuerpos antifosfolípidos, el denominado síndrome antifosfolípidos (SAF) catastrófico, el cual comenzó como un cuadro recurrente de trombosis mesentérica, con antecedentes de insuficiencia venosa y úlceras distales probablemente asociadas a un SAF no identificado, ameritando manejo en terapia intensiva y la consulta por el experto mundial Dr...
2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
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