Siegfried K Wagner, Praveen J Patel, Josef Huemer, Hagar Khalid, Kelsey V Stuart, Colin J Chu, Dominic J Williamson, Robbert R Struyven, David Romero-Bascones, Paul J Foster, Anthony P Khawaja, Axel Petzold, Konstantinos Balaskas, Mario Cortina-Borja, Iain Chapple, Thomas Dietrich, Jugnoo S Rahi, Alastair K Denniston, Pearse A Keane
PURPOSE: Periodontitis, a ubiquitous severe gum disease affecting the teeth and surrounding alveolar bone, can heighten systemic inflammation. We investigated the association between very severe periodontitis and early biomarkers of age-related macular degeneration (AMD), in individuals with no eye disease. DESIGN: Cross-sectional analysis of the prospective community-based cohort United Kingdom (UK) Biobank. PARTICIPANTS: Sixty-seven thousand three hundred eleven UK residents aged 40 to 70 years recruited between 2006 and 2010 underwent retinal imaging...
2024: Ophthalmol Sci